|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
30-446 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 727.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELL 109
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKFK 189
Cdd:pfam00709 81 ELEERGID-VPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFREKLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLFPSIN---VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 266
Cdd:pfam00709 159 ALLELKNKLLEKLYgepLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 267 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 346
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 347 YTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVRFLE 426
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYEL-DGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 308191525 427 SELSVPVRWVGVGKGRESII 446
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
28-446 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 653.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDE 107
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 108 LLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKggksLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDK 187
Cdd:smart00788 81 IEELEAKGVD-VKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVLREK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 188 FKSIVATHVRLFPSIN----VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:smart00788 155 LEELLDYKNFLLKKLYgaepVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:smart00788 235 SNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKL-DGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIE 393
|
410 420
....*....|....*....|...
gi 308191525 424 FLESELSVPVRWVGVGKGRESII 446
Cdd:smart00788 394 RIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
25-449 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 634.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 25 KSKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSL 104
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 105 FDELLKNQAKGlSHLENRLIISDRAHLVFDFHQHVDGMQEAE--KGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFN 182
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQAIDGIQESEkgKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NFE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 183 LFSDKFKSIVATHVRLFPSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 262
Cdd:PTZ00350 169 TFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 263 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 342
Cdd:PTZ00350 249 SSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 343 LVNGYTCICITKLDILDTMAEIKVAVGYKrSNGEKL--DHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQN 420
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYK-NKGTGLeiGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420
....*....|....*....|....*....
gi 308191525 421 YVRFLESELSVPVRWVGVGKGRESIINVH 449
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
28-449 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDE 107
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 108 LLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDK 187
Cdd:COG0104 81 IDGLEARGVD-VRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVLREK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 188 FKSIVATHVRLFPSIN----VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:COG0104 159 LEELLEYKNFLLEKLYgaepLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:COG0104 239 SNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKrSNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYE-LDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVE 397
|
410 420
....*....|....*....|....*.
gi 308191525 424 FLESELSVPVRWVGVGKGRESIINVH 449
Cdd:COG0104 398 RIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
27-446 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 524.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 27 KVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFD 106
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 107 ELLKNQAKGLSHLEnRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGEllgdfnlfsd 186
Cdd:cd03108 81 EIEELEKKGIDVKG-RLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD---------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 187 kfksivathvrlfpsinvdvdaelarykdyaekvrPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 266
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 267 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 346
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 347 YTCICITKLDIldtmaeikvavgykrsngekldhfpgtiaelgsieveyanlpgwqtstehirnfkelpeNAQNYVRFLE 426
Cdd:cd03108 275 LTELALTKLDV-----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|
gi 308191525 427 SELSVPVRWVGVGKGRESII 446
Cdd:cd03108 296 ELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
30-449 |
3.21e-180 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 509.78 E-value: 3.21e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELl 109
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEM- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLSHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDfNLFSDKFK 189
Cdd:TIGR00184 80 EYLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAFAEKAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLF----PSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 265
Cdd:TIGR00184 159 NILEYLNEQLvkyyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 266 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 345
Cdd:TIGR00184 239 TTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 346 GYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVRFL 425
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERI 397
|
410 420
....*....|....*....|....
gi 308191525 426 ESELSVPVRWVGVGKGRESIINVH 449
Cdd:TIGR00184 398 EELTGVPVTIISTGPEREQTIDLR 421
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
28-346 |
3.03e-31 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 121.32 E-value: 3.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLA--SEVDIVCRCqGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCISV-IGNGVVIHLPS 103
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 104 LFDELLKNQAKGLShLENRLIISDRAHLVfDFHQHVDgmQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 183
Cdd:NF038379 80 LREEIEELEDAGHD-VGKRLLIHEQATVI-ELHKHVE--EEAGPMTK-IGSTKKGIGAARAAKIRRNPSTLGDAEGDFGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 184 FSDKFksivathvrlfpsINVDVDAELARYKDYaekvrpyvkdticflHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:NF038379 155 GAVRD-------------QPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQ--TIGEVIGVVKAYTTRVGD-----GPFPTE----QLnevgdllqtrGFEVGVT--TKRKRRC 330
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEttweEL----------GLPEELTtvTKKVRRV 276
|
330
....*....|....*.
gi 308191525 331 GWLDIPLLKYTSLVNG 346
Cdd:NF038379 277 GTFSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
30-446 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 727.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELL 109
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKFK 189
Cdd:pfam00709 81 ELEERGID-VPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFREKLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLFPSIN---VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 266
Cdd:pfam00709 159 ALLELKNKLLEKLYgepLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 267 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 346
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 347 YTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVRFLE 426
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYEL-DGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 308191525 427 SELSVPVRWVGVGKGRESII 446
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
28-446 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 653.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDE 107
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 108 LLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKggksLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDK 187
Cdd:smart00788 81 IEELEAKGVD-VKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLF-DEEVLREK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 188 FKSIVATHVRLFPSIN----VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:smart00788 155 LEELLDYKNFLLKKLYgaepVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:smart00788 235 SNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKL-DGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIE 393
|
410 420
....*....|....*....|...
gi 308191525 424 FLESELSVPVRWVGVGKGRESII 446
Cdd:smart00788 394 RIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
25-449 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 634.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 25 KSKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSL 104
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 105 FDELLKNQAKGlSHLENRLIISDRAHLVFDFHQHVDGMQEAE--KGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFN 182
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQAIDGIQESEkgKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-NFE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 183 LFSDKFKSIVATHVRLFPSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 262
Cdd:PTZ00350 169 TFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 263 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 342
Cdd:PTZ00350 249 SSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 343 LVNGYTCICITKLDILDTMAEIKVAVGYKrSNGEKL--DHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQN 420
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYK-NKGTGLeiGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420
....*....|....*....|....*....
gi 308191525 421 YVRFLESELSVPVRWVGVGKGRESIINVH 449
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
28-449 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 627.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDE 107
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 108 LLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDK 187
Cdd:COG0104 81 IDGLEARGVD-VRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEVLREK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 188 FKSIVATHVRLFPSIN----VDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:COG0104 159 LEELLEYKNFLLEKLYgaepLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:COG0104 239 SNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKrSNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYE-LDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVE 397
|
410 420
....*....|....*....|....*.
gi 308191525 424 FLESELSVPVRWVGVGKGRESIINVH 449
Cdd:COG0104 398 RIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
26-446 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 613.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 26 SKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSL 104
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 105 FDELLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLF 184
Cdd:PLN02513 82 FEEIDGLESNGVS-CEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLR-HMDTF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 185 SDKFKSIVATHVRLFPSINVD---VDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 261
Cdd:PLN02513 160 AEKLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 262 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYT 341
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 342 SLVNGYTCICITKLDILDTMAEIKVAVGYKRSNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNY 421
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*
gi 308191525 422 VRFLESELSVPVRWVGVGKGRESII 446
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDALI 424
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
27-449 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 605.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 27 KVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFD 106
Cdd:PRK01117 2 KNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 107 ELLKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSD 186
Cdd:PRK01117 82 EIDELEARGVD-VRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 187 KFKSIVATH----VRLFPSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVT 262
Cdd:PRK01117 160 KLEENLEYKnfllTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 263 SSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTS 342
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 343 LVNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYV 422
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYI 398
|
410 420
....*....|....*....|....*..
gi 308191525 423 RFLESELSVPVRWVGVGKGRESIINVH 449
Cdd:PRK01117 399 KRIEELTGVPISIISTGPDRDQTIILR 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
27-446 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 524.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 27 KVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFD 106
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 107 ELLKNQAKGLSHLEnRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGEllgdfnlfsd 186
Cdd:cd03108 81 EIEELEKKGIDVKG-RLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD---------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 187 kfksivathvrlfpsinvdvdaelarykdyaekvrPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNC 266
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 267 SIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNG 346
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 347 YTCICITKLDIldtmaeikvavgykrsngekldhfpgtiaelgsieveyanlpgwqtstehirnfkelpeNAQNYVRFLE 426
Cdd:cd03108 275 LTELALTKLDV-----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|
gi 308191525 427 SELSVPVRWVGVGKGRESII 446
Cdd:cd03108 296 ELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
30-449 |
3.21e-180 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 509.78 E-value: 3.21e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELl 109
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEM- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLSHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDfNLFSDKFK 189
Cdd:TIGR00184 80 EYLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAFAEKAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLF----PSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 265
Cdd:TIGR00184 159 NILEYLNEQLvkyyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 266 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 345
Cdd:TIGR00184 239 TTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 346 GYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVRFL 425
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERI 397
|
410 420
....*....|....*....|....
gi 308191525 426 ESELSVPVRWVGVGKGRESIINVH 449
Cdd:TIGR00184 398 EELTGVPVTIISTGPEREQTIDLR 421
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
29-446 |
2.06e-126 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 373.13 E-value: 2.06e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 29 DVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDEL 108
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEEC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 109 LKNQAKGLShLENRLIISDRAHLVFDFHQHVDGMQEAEKGG-KSLGTTKKGIGPAYSSKATRNGIRVGELLGdfNLFSDK 187
Cdd:PRK13787 84 DRLQKEGFP-VKDKLLLSDACHLLFPYHSQIDSARETTSSQeHKIGTTKKGIGICYADKMMRTGLRVGDLLD--KSYKRR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 188 FKSIVATH----VRLFPSINVDVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:PRK13787 161 LKHLVDEKnrelDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:PRK13787 241 SNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAElgSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:PRK13787 321 INGITSIALTKIDILSDYDTIPVAVGYKL-NGKTLDCFPSQGLE--KVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|...
gi 308191525 424 FLESELSVPVRWVGVGKGRESII 446
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDTI 420
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
31-443 |
1.67e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 357.19 E-value: 1.67e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 31 VLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHlPSLFDELLK 110
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVID-PFRFAEERE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 111 NQAKGlsHLENRLIISDRAHLVFDFHQHVDGmqeaekGGKSLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKFKS 190
Cdd:PRK13788 85 NLRAG--GLNPKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLL-DEAVLRERVER 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 191 IVATHvrlfPSINVD-----VDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 265
Cdd:PRK13788 156 LLEAK----PNSTREagwdtVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSSH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 266 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRG----FEVGVTTKRKRRCGWLDIPLLKYT 341
Cdd:PRK13788 232 PTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKYA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 342 SLVNGYTCICITKLDILDTMAEIKVAVGYkRSNGekldhfpgtiaelgsiEVEYANLPGWQTsTEHIRNFKELPENAQNY 421
Cdd:PRK13788 312 CEVNGFDGLVLTKLDVLSGLEKVKVCVEY-DDDG----------------QPVYKELPGWGD-LDGVKSREALPKEAQAY 373
|
410 420
....*....|....*....|..
gi 308191525 422 VRFLESELSVPVRWVGVGKGRE 443
Cdd:PRK13788 374 LELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
30-443 |
3.52e-115 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 344.48 E-value: 3.52e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCIsVIGNGVVIHLPSLFDELL 109
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLSHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKFK 189
Cdd:PRK13786 83 MLEKHGVKVDAEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLV-DKERLMRRLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLF------PSINVDvDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:PRK13786 161 ELAPQKEKEIkelggdPSIVRD-EALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSL 343
Cdd:PRK13786 240 SSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 344 VNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLPGWQTSTEHIRNFKELPENAQNYVR 423
Cdd:PRK13786 320 LNGYTEIALTKLDVLTGLDPIKICVGYEL-DGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVE 398
|
410 420
....*....|....*....|
gi 308191525 424 FLESELSVPVRWVGVGKGRE 443
Cdd:PRK13786 399 RLEELMGVPIKYISVGPGRE 418
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
31-446 |
2.76e-113 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 340.58 E-value: 2.76e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 31 VLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKcISVIGNGVVIHLPSLFDELLK 110
Cdd:PRK13785 5 IVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGK-IGVLGNGCVVNPETLFDEIDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 111 NQAKGlshLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSL--GTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKF 188
Cdd:PRK13785 84 LRERG---LDPDVRVAERAHVILPYHRVLDGIEEEAKSDSDLevGTTGRGIGPTYEDKAGRRGVRVGDLL-DPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 189 KSIVATHVRLFPSI----------NVDVDAELARYKDYAEKVRPYVKDTIC--FLHTALRNGKTILVEGANAAMLDIDFG 256
Cdd:PRK13785 160 EYVVPQKRALAEDVygldasetpeAFDVDALFEEYREYGERLAEEDMTVNAgdFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 257 TYPYVTSSNCSIGGVLTGLGLPPQTI--GEVIGVVKAYTTRVGDGPFPTE---------------QLNEVGDLLQTRGFE 319
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVgqGEVVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 320 VGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICITKLDILDTMAEIKVAVGYKRsNGEKLDHFPGTIAELGSIEVEYANLP 399
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYEL-DGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 308191525 400 GWQT---STEHIRNFKELPENAQNYVRFLESELSVPVRWVGVGKGRESII 446
Cdd:PRK13785 399 GWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETV 448
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
30-448 |
3.01e-113 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 338.62 E-value: 3.01e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVvaNGTEFDF--HLLPSGVVNEKCISVIGNGVVIHLPSLFDE 107
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTV--NYGDFKVvhHLLPSADFKKNVGAAIGNGVVLDLEVLVEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 108 L--LKNQAKGLShleNRLIISDRAHLVFDFHQHVDGMQEAEKGgKSLGTTKKGIGPAYSSKATRNGIRVGELlGDFNLFS 185
Cdd:PRK13783 82 LeeLKEKFPDYS---GRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADL-FDEEKLR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 186 DKFKSIVATHVRLFpSINVDVDAELARYKDYAEKVRPYVKDTIcFLHTALRNgKTILVEGANAAMLDIDFGTYPYVTSSN 265
Cdd:PRK13783 157 EFLEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKIKDLVVSPV-EIKRILEE-KSVLFEGTQGVLLDLDVGTYPYVTSSN 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 266 CSIGGVLTGLGLPPQtIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 345
Cdd:PRK13783 234 CSTTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVS 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 346 GYTCICITKLDILDTMAEIKVAVGYKrSNGEKLDHfPGTIAELGSIEVEYANLPGWQTSTEhiRNFKElpenaqnYVRFL 425
Cdd:PRK13783 313 GVDSLVMTKADVLNGFEKIKVCVRYE-IGGKEVRD-PSSLRDLEKAEPVYEEFDGWKSLED--KNFLK-------FVDFI 381
|
410 420
....*....|....*....|...
gi 308191525 426 ESELSVPVRWVGVGKGRESIINV 448
Cdd:PRK13783 382 ERETGRKIAYISTGPKIEEIVEV 404
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
30-446 |
7.41e-100 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 305.41 E-value: 7.41e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 30 VVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDELL 109
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 110 KNQAKGLSHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLgDFNLFSDKFK 189
Cdd:PRK13784 85 RLQAKGIAISAENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLF-DKDLLRSRLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 190 SIVATHVRLFPSINV----DVDAELARYKDYAEKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSN 265
Cdd:PRK13784 163 ISLAEKETLFRDLYKveypTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTSSN 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 266 CSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVN 345
Cdd:PRK13784 243 TSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAKCS 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 346 GYTCICITKLDILDTMAEIKVAVGYKRSNGEKLDHFPGTiaELGSIEVEYANLPGWqtSTEHIRNFKELPENAQNYVRFL 425
Cdd:PRK13784 323 NLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPGI--DLYKVEPILVEMEPF--SIDETVTKDNMPAALKTYLKTI 398
|
410 420
....*....|....*....|.
gi 308191525 426 ESELSVPVRWVGVGKGRESII 446
Cdd:PRK13784 399 ENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
28-448 |
5.29e-61 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 201.65 E-value: 5.29e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLA--SEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLF 105
Cdd:PRK04293 3 CTIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 106 DELLKNQAKGlshlenRLIISDRAHLVFDFHQhvdgmqEAEKGG----KSLGTTKKGIGPAYSSKATRNgirvgellgdf 181
Cdd:PRK04293 83 KEVEELNVGG------RVFVDYRCGIIEEKHV------EEDRSDehlsKKIGSTGTGCGPANADRVLRR----------- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 182 nlfsdkfksivathvrlfpsinvdvdAELAryKDYAEkVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 261
Cdd:PRK04293 140 --------------------------LKLA--KDVEE-LEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 262 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEVGdllQTRGF-EVGVTTKRKRRCGWLDIPLLKY 340
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEA---EKLGLvEYGTVTGRRRRVGPFDFELARR 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 341 TSLVNGYTCICITKLDILDtmaeiKVAVGykrsngekldhfpgtiaelgsieveyanlpgwqtstehIRNFKELPENAQN 420
Cdd:PRK04293 268 AARINGATQIAITKLDKLD-----KEAYG--------------------------------------VTEYDKLPPEAKK 304
|
410 420
....*....|....*....|....*...
gi 308191525 421 YVRFLESELSVPVRWVGVGKGRESIINV 448
Cdd:PRK04293 305 FIEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
28-346 |
3.03e-31 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 121.32 E-value: 3.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLA--SEVDIVCRCqGGNNAGHTVV-ANGTEFDFHLLPSGVVNEKCISV-IGNGVVIHLPS 103
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAerAAPDVVVRA-AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 104 LFDELLKNQAKGLShLENRLIISDRAHLVfDFHQHVDgmQEAEKGGKsLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 183
Cdd:NF038379 80 LREEIEELEDAGHD-VGKRLLIHEQATVI-ELHKHVE--EEAGPMTK-IGSTKKGIGAARAAKIRRNPSTLGDAEGDFGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 184 FSDKFksivathvrlfpsINVDVDAELARYKDYaekvrpyvkdticflHTALRNGKTILVEGANAAMLDIDFGTYPYVTS 263
Cdd:NF038379 155 GAVRD-------------QPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCTS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 264 SNCSIGGVLTGLGLPPQ--TIGEVIGVVKAYTTRVGD-----GPFPTE----QLnevgdllqtrGFEVGVT--TKRKRRC 330
Cdd:NF038379 207 RDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAGwsgnsYPDQGEttweEL----------GLPEELTtvTKKVRRV 276
|
330
....*....|....*.
gi 308191525 331 GWLDIPLLKYTSLVNG 346
Cdd:NF038379 277 GTFSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
28-303 |
4.01e-16 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 80.87 E-value: 4.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 28 VDVVLGAQWGDEGKGKVVDMLASEVDIVC--RCQGGNNAGHTVVAN-GTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSL 104
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHPLCTCiaRVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSF 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 105 FD-ELLKNQAKGLSHlENRLIISDRAhLVFDFHQHVDGMqeaekGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNL 183
Cdd:PTZ00351 251 MEkEIIQLIDAGIDY-RDRLFIGNVC-IVTPYHKLLDLL-----GSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNDDET 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308191525 184 FSDKFKSIVATHVRLFPSINVDvDAELARY------------------------------KDYAEKVR-----PYVKDTI 228
Cdd:PTZ00351 324 LRKRLEKDMDTYLGLLKVKNLS-DADVVRLcreensdgvvrvpdyviafaqakdkveflvKLYRDRVRhnpdfPARCDVT 402
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 308191525 229 CFLHTALRNGKTILVEGANAAML-DIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVI-GVVKAY-TTRVGDGPFPT 303
Cdd:PTZ00351 403 YELHAAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGACPS 480
|
|
| |
