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Conserved domains on  [gi|937909293|dbj|BAS84213|]
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Os03g0352800 [Oryza sativa Japonica Group]

Protein Classification

acyl carrier protein( domain architecture ID 516)

acyl carrier protein may function as a carrier of the growing fatty acid chain in fatty acid biosynthesis or as the carrier of activated (amino) acid groups in polyketide synthases and non-ribosomal peptide synthases

Gene Ontology:  GO:0006633
PubMed:  30543875

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PP-binding super family cl09936
Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached ...
 44-135 8.26e-30

Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.


The actual alignment was detected with superfamily member PTZ00171:

Pssm-ID: 447865  Cd Length: 148  Bit Score: 105.17  E-value: 8.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937909293  44 SSEEAKGSFLDKAEVTERIVKVVRNFQKIDDpAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKV 123
Cdd:PTZ00171  57 RSSKSKQYLLSKEDVLTRVKKVVKNFEKVDA-SKITPESNFVKDLGADSLDVVELLIAIEQEFNLTIPDHDAEKIKTVQD 135

                         90
                 ....*....|..
gi 937909293 124 AVDFIASHPQAK 135
Cdd:PTZ00171 136 AIDYIEQNNMAK 147
 
Name Accession Description Interval E-value
PTZ00171 PTZ00171
acyl carrier protein; Provisional
 44-135 8.26e-30

acyl carrier protein; Provisional


Pssm-ID: 240304  Cd Length: 148  Bit Score: 105.17  E-value: 8.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937909293  44 SSEEAKGSFLDKAEVTERIVKVVRNFQKIDDpAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKV 123
Cdd:PTZ00171  57 RSSKSKQYLLSKEDVLTRVKKVVKNFEKVDA-SKITPESNFVKDLGADSLDVVELLIAIEQEFNLTIPDHDAEKIKTVQD 135

                         90
                 ....*....|..
gi 937909293 124 AVDFIASHPQAK 135
Cdd:PTZ00171 136 AIDYIEQNNMAK 147
acyl_carrier TIGR00517
acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser ...
 55-132 1.90e-24

acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser residue. It acts as a carrier of the growing fatty acid chain, which is bound to the prosthetic group, during fatty acid biosynthesis. Homologous phosphopantetheine-binding domains are found in longer proteins. Acyl carrier proteins scoring above the noise cutoff but below the trusted cutoff may be specialized versions. These include those involved in mycolic acid biosynthesis in the Mycobacteria, lipid A biosynthesis in Rhizobium, actinorhodin polyketide synthesis in Streptomyces coelicolor, etc. This protein is not found in the Archaea.Gene name acpP.S (Ser) at position 37 in the seed alignment, in the motif DSLD, is the phosphopantetheine attachment site. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 213536 [Multi-domain]  Cd Length: 77  Bit Score: 88.99  E-value: 1.90e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293   55 KAEVTERIVKVVRNfQKIDDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASHP 132
Cdd:TIGR00517   1 MQEIFEKVKAIIKE-QLNVDEDQITTDARFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKIATVGDAVNYIEENQ 77
AcpP COG0236
Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the ...
 54-131 2.37e-19

Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440006 [Multi-domain]  Cd Length: 80  Bit Score: 76.05  E-value: 2.37e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293  54 DKAEVTERIVKVVRNFQKIDdPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASH 131
Cdd:COG0236    2 PREELEERLAEIIAEVLGVD-PEEITPDDSFFEDLGLDSLDAVELIAALEEEFGIELPDTELFEYPTVADLADYLEEK 78
PP-binding pfam00550
Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached ...
 60-122 2.99e-08

Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.


Pssm-ID: 425746 [Multi-domain]  Cd Length: 62  Bit Score: 47.17  E-value: 2.99e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 937909293   60 ERIVKVVRNFQKIDDPAkVTPDAHFKnDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIK 122
Cdd:pfam00550   1 ERLRELLAEVLGVPAEE-IDPDTDLF-DLGLDSLLAVELIARLEEEFGVEIPPSDLFEHPTLA 61
PKS_PP smart00823
Phosphopantetheine attachment site; Phosphopantetheine (or pantetheine 4' phosphate) is the ...
 56-111 9.40e-07

Phosphopantetheine attachment site; Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.


Pssm-ID: 214834 [Multi-domain]  Cd Length: 86  Bit Score: 43.78  E-value: 9.40e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 937909293    56 AEVTERIVKVVRNFQKIDDPAKVTPDAHFKnDLGLDSLDAVEVVMALEEEFGFEIP 111
Cdd:smart00823  11 RLLLDLVREQVAAVLGHAAAEAIDPDRPFR-DLGLDSLMAVELRNRLEAATGLRLP 65
 
Name Accession Description Interval E-value
PTZ00171 PTZ00171
acyl carrier protein; Provisional
 44-135 8.26e-30

acyl carrier protein; Provisional


Pssm-ID: 240304  Cd Length: 148  Bit Score: 105.17  E-value: 8.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937909293  44 SSEEAKGSFLDKAEVTERIVKVVRNFQKIDDpAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKV 123
Cdd:PTZ00171  57 RSSKSKQYLLSKEDVLTRVKKVVKNFEKVDA-SKITPESNFVKDLGADSLDVVELLIAIEQEFNLTIPDHDAEKIKTVQD 135

                         90
                 ....*....|..
gi 937909293 124 AVDFIASHPQAK 135
Cdd:PTZ00171 136 AIDYIEQNNMAK 147
acyl_carrier TIGR00517
acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser ...
 55-132 1.90e-24

acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser residue. It acts as a carrier of the growing fatty acid chain, which is bound to the prosthetic group, during fatty acid biosynthesis. Homologous phosphopantetheine-binding domains are found in longer proteins. Acyl carrier proteins scoring above the noise cutoff but below the trusted cutoff may be specialized versions. These include those involved in mycolic acid biosynthesis in the Mycobacteria, lipid A biosynthesis in Rhizobium, actinorhodin polyketide synthesis in Streptomyces coelicolor, etc. This protein is not found in the Archaea.Gene name acpP.S (Ser) at position 37 in the seed alignment, in the motif DSLD, is the phosphopantetheine attachment site. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 213536 [Multi-domain]  Cd Length: 77  Bit Score: 88.99  E-value: 1.90e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293   55 KAEVTERIVKVVRNfQKIDDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASHP 132
Cdd:TIGR00517   1 MQEIFEKVKAIIKE-QLNVDEDQITTDARFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKIATVGDAVNYIEENQ 77
acpP PRK00982
acyl carrier protein; Provisional
 55-131 6.60e-23

acyl carrier protein; Provisional


Pssm-ID: 179197 [Multi-domain]  Cd Length: 78  Bit Score: 85.22  E-value: 6.60e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293  55 KAEVTERIVK-VVRNFQKidDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASH 131
Cdd:PRK00982   1 MSEIFEKVKKiIVEQLGV--DEEEVTPEASFVDDLGADSLDTVELVMALEEEFGIEIPDEDAEKIKTVGDAVDYIEKH 76
acpP CHL00124
acyl carrier protein; Validated
 54-135 5.48e-20

acyl carrier protein; Validated


Pssm-ID: 177047 [Multi-domain]  Cd Length: 82  Bit Score: 77.75  E-value: 5.48e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937909293  54 DKAEVTERIVKVVRNfQKIDDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASHPQ 133
Cdd:CHL00124   2 TKNDIFEKVQSIVAE-QLGIEKSEVTLDANFTRDLGADSLDVVELVMAIEEKFDIEIPDEDAEKISTLQEAVDFISQKIN 80


                 ..
gi 937909293 134 AK 135
Cdd:CHL00124  81 KK 82
AcpP COG0236
Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the ...
 54-131 2.37e-19

Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440006 [Multi-domain]  Cd Length: 80  Bit Score: 76.05  E-value: 2.37e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293  54 DKAEVTERIVKVVRNFQKIDdPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASH 131
Cdd:COG0236    2 PREELEERLAEIIAEVLGVD-PEEITPDDSFFEDLGLDSLDAVELIAALEEEFGIELPDTELFEYPTVADLADYLEEK 78
PRK12449 PRK12449
acyl carrier protein; Provisional
 55-131 4.39e-10

acyl carrier protein; Provisional


Pssm-ID: 183533 [Multi-domain]  Cd Length: 80  Bit Score: 52.40  E-value: 4.39e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 937909293  55 KAEVTERIVKVVRNfQKIDDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIKVAVDFIASH 131
Cdd:PRK12449   3 REEIFERLINLIQK-QRSYLSLAITEQTHLKDDLAVDSIELVEFIINVEDEFHIAIPDEDVEDMVSMGDLLDYLVQR 78
PP-binding pfam00550
Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached ...
 60-122 2.99e-08

Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.


Pssm-ID: 425746 [Multi-domain]  Cd Length: 62  Bit Score: 47.17  E-value: 2.99e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 937909293   60 ERIVKVVRNFQKIDDPAkVTPDAHFKnDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSIK 122
Cdd:pfam00550   1 ERLRELLAEVLGVPAEE-IDPDTDLF-DLGLDSLLAVELIARLEEEFGVEIPPSDLFEHPTLA 61
PKS_PP smart00823
Phosphopantetheine attachment site; Phosphopantetheine (or pantetheine 4' phosphate) is the ...
 56-111 9.40e-07

Phosphopantetheine attachment site; Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.


Pssm-ID: 214834 [Multi-domain]  Cd Length: 86  Bit Score: 43.78  E-value: 9.40e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 937909293    56 AEVTERIVKVVRNFQKIDDPAKVTPDAHFKnDLGLDSLDAVEVVMALEEEFGFEIP 111
Cdd:smart00823  11 RLLLDLVREQVAAVLGHAAAEAIDPDRPFR-DLGLDSLMAVELRNRLEAATGLRLP 65
PRK06508 PRK06508
acyl carrier protein; Provisional
 74-111 9.68e-07

acyl carrier protein; Provisional


Pssm-ID: 180597  Cd Length: 93  Bit Score: 44.04  E-value: 9.68e-07
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 937909293  74 DPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIP 111
Cdd:PRK06508  19 PRDTITPESHTIDDLGIDSLDFLDIVFAIDKAFGIKLP 56
PRK07081 PRK07081
acyl carrier protein; Provisional
 87-128 3.46e-05

acyl carrier protein; Provisional


Pssm-ID: 180828  Cd Length: 83  Bit Score: 39.56  E-value: 3.46e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 937909293  87 DLGLDSLDAVEVVMALEEEFGFEIPDNEADK-----IDSIKVAVDFI 128
Cdd:PRK07081  30 EAGLSSLATVQLMLAIEDAFDIEIPDEMLNRklfasIDALAGAVTQL 76
PRK05350 PRK05350
acyl carrier protein; Provisional
 53-110 4.30e-05

acyl carrier protein; Provisional


Pssm-ID: 180033  Cd Length: 82  Bit Score: 39.59  E-value: 4.30e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 937909293  53 LDKAEVTERIVKVVRNFQKIDdPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEI 110
Cdd:PRK05350   2 MTREEILERLRAILVELFEID-PEDITPEANLYEDLDLDSIDAVDLVVHLQKLTGKKI 58
PRK09184 PRK09184
acyl carrier protein; Provisional
 74-131 1.46e-04

acyl carrier protein; Provisional


Pssm-ID: 181682  Cd Length: 89  Bit Score: 38.11  E-value: 1.46e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 937909293  74 DPAKVTPDAHFKND-LGLDSLDAVEVVMALEEEFGFEI----PDNEadKI-DSIKVAVDFIASH 131
Cdd:PRK09184  25 QPESIDADAPLYGEgLGLDSIDILEIALVISKRYGFQLrsdnPDNQ--RIfASLRALAAYVAAH 86
PRK08172 PRK08172
acyl carrier protein;
60-121 9.78e-04

acyl carrier protein;


Pssm-ID: 181266  Cd Length: 82  Bit Score: 36.02  E-value: 9.78e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 937909293  60 ERIVKVVRNFQKIDDPAKVTPDAHFKNDLGLDSLDAVEVVMALEEEFGFEIPDNEADKIDSI 121
Cdd:PRK08172   6 EARVKKVITSCIAVDVDSINGQTHLVEDLYADSLDLIDIVFGLSEEFDISCNENDLPDMTTF 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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