NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1525818752|dbj|BAU59238|]
View 

CR1-alpha/23.3 kDa protein [Human adenovirus 4p]

Protein Classification

adenoE3CR1rpt and Adeno_E3 domain-containing protein( domain architecture ID 10024904)

adenoE3CR1rpt and Adeno_E3 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Adeno_E3 super family cl05534
Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein ...
76-209 3.62e-59

Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein does not seem to be essential for virus replication in cultured cells suggesting that the protein may function in virus-host interactions.


The actual alignment was detected with superfamily member pfam06040:

Pssm-ID: 253527  Cd Length: 126  Bit Score: 182.01  E-value: 3.62e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  76 LNGPANLTFStrrskLLLFRPFLPGIYQCVSGpcHHTFHLIPNTTSSPAPLLTNN-QTNHHQRYRRDLVESNTT-HTGGE 153
Cdd:pfam06040   1 IKTELRLSYG-----LPLLQPGLYNTYQCVQK--HHTFPLIPNTTNSTFPLPTNKlQTNLHHRFSRSLFESNTTtKTGGE 73
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1525818752 154 LRGPQLSGiyygPWEVVGLIALGLVAGGL-LALCYLYLPCFSYLVVLCCWFKKWGRS 209
Cdd:pfam06040  74 LRGLPTSG----PWVVAGLVTLGLVAGGLvLILCYLYTPCFSYLVVLCCWFKKWGPY 126
adenoE3CR1rpt TIGR04241
mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 ...
34-116 3.42e-24

mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 protein. It may occur once, twice, or three times.


:

Pssm-ID: 211964  Cd Length: 81  Bit Score: 91.29  E-value: 3.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  34 LTFTGNETELHLQCKPHKKYLTWLHQGSPIAvvnHCNDDGVLLNGPANLTFSTRRSKLLLFRPFLPGIYQCVSGPCHHTF 113
Cdd:TIGR04241   2 LYFTNSTTNITLNCSCFSTYILWTFNNSSCA---TYDNDGVLLPNNLSLTFSASSQKLTLFPPFVPGTYTCQAGPCQHTF 78

                  ...
gi 1525818752 114 HLI 116
Cdd:TIGR04241  79 KLV 81
 
Name Accession Description Interval E-value
Adeno_E3 pfam06040
Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein ...
76-209 3.62e-59

Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein does not seem to be essential for virus replication in cultured cells suggesting that the protein may function in virus-host interactions.


Pssm-ID: 253527  Cd Length: 126  Bit Score: 182.01  E-value: 3.62e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  76 LNGPANLTFStrrskLLLFRPFLPGIYQCVSGpcHHTFHLIPNTTSSPAPLLTNN-QTNHHQRYRRDLVESNTT-HTGGE 153
Cdd:pfam06040   1 IKTELRLSYG-----LPLLQPGLYNTYQCVQK--HHTFPLIPNTTNSTFPLPTNKlQTNLHHRFSRSLFESNTTtKTGGE 73
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1525818752 154 LRGPQLSGiyygPWEVVGLIALGLVAGGL-LALCYLYLPCFSYLVVLCCWFKKWGRS 209
Cdd:pfam06040  74 LRGLPTSG----PWVVAGLVTLGLVAGGLvLILCYLYTPCFSYLVVLCCWFKKWGPY 126
adenoE3CR1rpt TIGR04241
mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 ...
34-116 3.42e-24

mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 protein. It may occur once, twice, or three times.


Pssm-ID: 211964  Cd Length: 81  Bit Score: 91.29  E-value: 3.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  34 LTFTGNETELHLQCKPHKKYLTWLHQGSPIAvvnHCNDDGVLLNGPANLTFSTRRSKLLLFRPFLPGIYQCVSGPCHHTF 113
Cdd:TIGR04241   2 LYFTNSTTNITLNCSCFSTYILWTFNNSSCA---TYDNDGVLLPNNLSLTFSASSQKLTLFPPFVPGTYTCQAGPCQHTF 78

                  ...
gi 1525818752 114 HLI 116
Cdd:TIGR04241  79 KLV 81
 
Name Accession Description Interval E-value
Adeno_E3 pfam06040
Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein ...
76-209 3.62e-59

Adenovirus E3 protein; This family consists of several Adenovirus E3 proteins. The E3 protein does not seem to be essential for virus replication in cultured cells suggesting that the protein may function in virus-host interactions.


Pssm-ID: 253527  Cd Length: 126  Bit Score: 182.01  E-value: 3.62e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  76 LNGPANLTFStrrskLLLFRPFLPGIYQCVSGpcHHTFHLIPNTTSSPAPLLTNN-QTNHHQRYRRDLVESNTT-HTGGE 153
Cdd:pfam06040   1 IKTELRLSYG-----LPLLQPGLYNTYQCVQK--HHTFPLIPNTTNSTFPLPTNKlQTNLHHRFSRSLFESNTTtKTGGE 73
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1525818752 154 LRGPQLSGiyygPWEVVGLIALGLVAGGL-LALCYLYLPCFSYLVVLCCWFKKWGRS 209
Cdd:pfam06040  74 LRGLPTSG----PWVVAGLVTLGLVAGGLvLILCYLYTPCFSYLVVLCCWFKKWGPY 126
adenoE3CR1rpt TIGR04241
mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 ...
34-116 3.42e-24

mastadenovirus E3 CR1-alpha-1; This domain occurs only in the adenovirus E3 region CR1-alpha-1 protein. It may occur once, twice, or three times.


Pssm-ID: 211964  Cd Length: 81  Bit Score: 91.29  E-value: 3.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1525818752  34 LTFTGNETELHLQCKPHKKYLTWLHQGSPIAvvnHCNDDGVLLNGPANLTFSTRRSKLLLFRPFLPGIYQCVSGPCHHTF 113
Cdd:TIGR04241   2 LYFTNSTTNITLNCSCFSTYILWTFNNSSCA---TYDNDGVLLPNNLSLTFSASSQKLTLFPPFVPGTYTCQAGPCQHTF 78

                  ...
gi 1525818752 114 HLI 116
Cdd:TIGR04241  79 KLV 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH