NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17978218|emb|CAC86464|]
View 

2a protein [Tomato aspermy virus]

Protein Classification

Bromoviridae_RdRp domain-containing protein( domain architecture ID 10469888)

Bromoviridae_RdRp domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
RdRP_2 pfam00978
RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The ...
313-749 0e+00

RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The family also contains the following proteins: 2A protein from bromoviruses putative RNA dependent RNA polymerase from tobamoviruses Non structural polyprotein from togaviruses


:

Pssm-ID: 395779  Cd Length: 440  Bit Score: 554.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   313 NADYSVDIDRVRLKQSDLLAK-VIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFM 391
Cdd:pfam00978   1 TSDISLDLDDCRLDPSKSKPKpKDKEPYLVPVLRTAAPSPRQNTLKEVLLALKKRNFNVPELQESVDLDDTAERVAERFK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   392 LSFMNGDKLCSSNFINI----VSDFHAYMSKW-QSVLSYDDLPDLNAENLQFYEHMVKSDVKPSVTDTLNIDRPLPATIT 466
Cdd:pfam00978  81 KSFLDKEKLDKLDPIINttenVSRWLDKQSGKkAAQLKLDDLVPLHEVDLDRYKHMIKSDVKPKLDLSPQSERPALQTIT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   467 FHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLNK--FCLEIDLSKFDKSQGELHLMIQEGILNRL 544
Cdd:pfam00978 161 YHDKGVTAYFSPIFRELFERLLYVLKPKIVFPTGMTSSLIAEHFEFLDAseDFLEIDFSKFDKSQGELHLLVQLEILKLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   545 GCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAP 624
Cdd:pfam00978 241 GLDPELADLWFKFHRQSYIKDRKNGVGFSVDYQRKSGDANTYLGNTLVTMAMLASVYDLEKIDCAAFSGDDSLIFSPKPI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   625 VGDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNtFSVPDPLREIQRLGSKKIPldEDDRSLHAHFMSFVDRLK-FL 703
Cdd:pfam00978 321 EDPASRFATLFNMEAKVFDPSVPYFCSKFLLEVDGGA-FFVPDPLKLLQKLGKKKIP--DDEQHLDEIFTSLCDLTKsFN 397
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 17978218   704 NHMNQTSMTQLSLFYEMKYRKSGDDillVLGAFNKYTANFNAYKEL 749
Cdd:pfam00978 398 DDCVVLELLDLAVARYYKYAPEGYA---ALCALHKALSSFTLFFSL 440
 
Name Accession Description Interval E-value
RdRP_2 pfam00978
RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The ...
313-749 0e+00

RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The family also contains the following proteins: 2A protein from bromoviruses putative RNA dependent RNA polymerase from tobamoviruses Non structural polyprotein from togaviruses


Pssm-ID: 395779  Cd Length: 440  Bit Score: 554.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   313 NADYSVDIDRVRLKQSDLLAK-VIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFM 391
Cdd:pfam00978   1 TSDISLDLDDCRLDPSKSKPKpKDKEPYLVPVLRTAAPSPRQNTLKEVLLALKKRNFNVPELQESVDLDDTAERVAERFK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   392 LSFMNGDKLCSSNFINI----VSDFHAYMSKW-QSVLSYDDLPDLNAENLQFYEHMVKSDVKPSVTDTLNIDRPLPATIT 466
Cdd:pfam00978  81 KSFLDKEKLDKLDPIINttenVSRWLDKQSGKkAAQLKLDDLVPLHEVDLDRYKHMIKSDVKPKLDLSPQSERPALQTIT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   467 FHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLNK--FCLEIDLSKFDKSQGELHLMIQEGILNRL 544
Cdd:pfam00978 161 YHDKGVTAYFSPIFRELFERLLYVLKPKIVFPTGMTSSLIAEHFEFLDAseDFLEIDFSKFDKSQGELHLLVQLEILKLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   545 GCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAP 624
Cdd:pfam00978 241 GLDPELADLWFKFHRQSYIKDRKNGVGFSVDYQRKSGDANTYLGNTLVTMAMLASVYDLEKIDCAAFSGDDSLIFSPKPI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   625 VGDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNtFSVPDPLREIQRLGSKKIPldEDDRSLHAHFMSFVDRLK-FL 703
Cdd:pfam00978 321 EDPASRFATLFNMEAKVFDPSVPYFCSKFLLEVDGGA-FFVPDPLKLLQKLGKKKIP--DDEQHLDEIFTSLCDLTKsFN 397
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 17978218   704 NHMNQTSMTQLSLFYEMKYRKSGDDillVLGAFNKYTANFNAYKEL 749
Cdd:pfam00978 398 DDCVVLELLDLAVARYYKYAPEGYA---ALCALHKALSSFTLFFSL 440
Bromoviridae_RdRp cd23252
RNA-dependent RNA polymerase (RdRp) in the family Bromoviridae of positive-sense ...
315-676 0e+00

RNA-dependent RNA polymerase (RdRp) in the family Bromoviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Bromoviridae, order Martellivirales. The Bromoviridae family of plant viruses contains tri-segmented, (+)ssRNA viruses with a total genome size of about 8 kb. There are six genera in this family: Alfamovirus, Anulavirus, Bromovirus, Cucumovirus, Ilarvirus, and Oleavirus. Bromoviridae virions are variable in morphology (spherical or bacilliform) and are transmitted mechanically, in/on the pollen and non-persistently by insect vectors. Members of the family cause major disease epidemics in fruit, vegetable and fodder crops such as tomato, cucurbits, bananas, and alfalfa. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438102  Cd Length: 332  Bit Score: 531.42  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 315 DYSVDIDRVRLKQSDLLAKVIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFMLSF 394
Cdd:cd23252   1 DISLDVDHCRLDQSDFNDWTKPDGYLEPVLNTGSGSKRVGTQREALLAIKKRNANVPELGDSVDLDRVSNAVANRFLTTV 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 395 MNGDKLcssnfinivsdfhaymskwqsvlsyddlpdlnaenlQFYEHMVKSDVKPSVTDTLNIDRPLPATITFHRKQLTS 474
Cdd:cd23252  81 IDVDRL------------------------------------DKYMHMIKSDLKPVEDDSLHVERPVPATITYHKKGIVM 124
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 475 QFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLN--KFCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISK 552
Cdd:cd23252 125 QFSPLFLAAFERLLRCLRSKIVIPSGKIHQLFMIDPSVLNasKHFKEIDFSKFDKSQGELHHEIQEHILNALGCPAPFTK 204
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 553 WWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTS--QFDKLIFSGDDSLGFSIKAPVG-DPS 629
Cdd:cd23252 205 WWFDFHRRSYISDRRAGVGFSVDFQRRTGDAFTYLGNTLVTLAELAYVYDLDdpNFDFVVASGDDSLIGSVEPLPRdDED 284
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*....
gi 17978218 630 LFTSLFNMEAKVMEpSVPYICSKFLLTDDFG--NTFSVPDPLREIQRLG 676
Cdd:cd23252 285 LFTTLFNFEAKFPH-NQPFICSKFLLSDEFGdeNVFSVPDPLKLLQRLG 332
 
Name Accession Description Interval E-value
RdRP_2 pfam00978
RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The ...
313-749 0e+00

RNA dependent RNA polymerase; This family may represent an RNA dependent RNA polymerase. The family also contains the following proteins: 2A protein from bromoviruses putative RNA dependent RNA polymerase from tobamoviruses Non structural polyprotein from togaviruses


Pssm-ID: 395779  Cd Length: 440  Bit Score: 554.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   313 NADYSVDIDRVRLKQSDLLAK-VIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFM 391
Cdd:pfam00978   1 TSDISLDLDDCRLDPSKSKPKpKDKEPYLVPVLRTAAPSPRQNTLKEVLLALKKRNFNVPELQESVDLDDTAERVAERFK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   392 LSFMNGDKLCSSNFINI----VSDFHAYMSKW-QSVLSYDDLPDLNAENLQFYEHMVKSDVKPSVTDTLNIDRPLPATIT 466
Cdd:pfam00978  81 KSFLDKEKLDKLDPIINttenVSRWLDKQSGKkAAQLKLDDLVPLHEVDLDRYKHMIKSDVKPKLDLSPQSERPALQTIT 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   467 FHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLNK--FCLEIDLSKFDKSQGELHLMIQEGILNRL 544
Cdd:pfam00978 161 YHDKGVTAYFSPIFRELFERLLYVLKPKIVFPTGMTSSLIAEHFEFLDAseDFLEIDFSKFDKSQGELHLLVQLEILKLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   545 GCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAP 624
Cdd:pfam00978 241 GLDPELADLWFKFHRQSYIKDRKNGVGFSVDYQRKSGDANTYLGNTLVTMAMLASVYDLEKIDCAAFSGDDSLIFSPKPI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218   625 VGDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNtFSVPDPLREIQRLGSKKIPldEDDRSLHAHFMSFVDRLK-FL 703
Cdd:pfam00978 321 EDPASRFATLFNMEAKVFDPSVPYFCSKFLLEVDGGA-FFVPDPLKLLQKLGKKKIP--DDEQHLDEIFTSLCDLTKsFN 397
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 17978218   704 NHMNQTSMTQLSLFYEMKYRKSGDDillVLGAFNKYTANFNAYKEL 749
Cdd:pfam00978 398 DDCVVLELLDLAVARYYKYAPEGYA---ALCALHKALSSFTLFFSL 440
Bromoviridae_RdRp cd23252
RNA-dependent RNA polymerase (RdRp) in the family Bromoviridae of positive-sense ...
315-676 0e+00

RNA-dependent RNA polymerase (RdRp) in the family Bromoviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Bromoviridae, order Martellivirales. The Bromoviridae family of plant viruses contains tri-segmented, (+)ssRNA viruses with a total genome size of about 8 kb. There are six genera in this family: Alfamovirus, Anulavirus, Bromovirus, Cucumovirus, Ilarvirus, and Oleavirus. Bromoviridae virions are variable in morphology (spherical or bacilliform) and are transmitted mechanically, in/on the pollen and non-persistently by insect vectors. Members of the family cause major disease epidemics in fruit, vegetable and fodder crops such as tomato, cucurbits, bananas, and alfalfa. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438102  Cd Length: 332  Bit Score: 531.42  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 315 DYSVDIDRVRLKQSDLLAKVIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFMLSF 394
Cdd:cd23252   1 DISLDVDHCRLDQSDFNDWTKPDGYLEPVLNTGSGSKRVGTQREALLAIKKRNANVPELGDSVDLDRVSNAVANRFLTTV 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 395 MNGDKLcssnfinivsdfhaymskwqsvlsyddlpdlnaenlQFYEHMVKSDVKPSVTDTLNIDRPLPATITFHRKQLTS 474
Cdd:cd23252  81 IDVDRL------------------------------------DKYMHMIKSDLKPVEDDSLHVERPVPATITYHKKGIVM 124
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 475 QFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLN--KFCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISK 552
Cdd:cd23252 125 QFSPLFLAAFERLLRCLRSKIVIPSGKIHQLFMIDPSVLNasKHFKEIDFSKFDKSQGELHHEIQEHILNALGCPAPFTK 204
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 553 WWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTS--QFDKLIFSGDDSLGFSIKAPVG-DPS 629
Cdd:cd23252 205 WWFDFHRRSYISDRRAGVGFSVDFQRRTGDAFTYLGNTLVTLAELAYVYDLDdpNFDFVVASGDDSLIGSVEPLPRdDED 284
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*....
gi 17978218 630 LFTSLFNMEAKVMEpSVPYICSKFLLTDDFG--NTFSVPDPLREIQRLG 676
Cdd:cd23252 285 LFTTLFNFEAKFPH-NQPFICSKFLLSDEFGdeNVFSVPDPLKLLQRLG 332
ps-ssRNAv_Martellivirales_RdRp cd23208
catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the order Martellivirales of ...
437-620 3.52e-75

catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the order Martellivirales of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the catalytic core domain of RdRp of RNA viruses belonging to the order Martellivirales, class Alsuviricetes. The order Martellivirales consists of seven families: Bromoviridae, Closteroviridae, Endornaviridae, Kitaviridae, Mayoviridae, Togaviridae, and Virgaviridae. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438058 [Multi-domain]  Cd Length: 190  Bit Score: 242.66  E-value: 3.52e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 437 QFYEHMVKSDVKPSVTDTLNIDRPLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVL--- 513
Cdd:cd23208   1 DKYEMMIKSDVKPKLDLTAQQEYPKLQTIVYHDKNITAIFCPIFKELFERLLSCLKKKVVIYTGMMTSAELNDFISAlhl 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 514 --NKFCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTL 591
Cdd:cd23208  81 esGYYVLEIDFSKFDKSQGALHLLTELLILRRLGVDEPLLVLWEFAHTQSTTRDINNGISFETAYQRKSGDAFTYFGNTL 160
                       170       180
                ....*....|....*....|....*....
gi 17978218 592 VTMSMFAWCYDTSQFDKLIFSGDDSLGFS 620
Cdd:cd23208 161 VTMAALLDVLDLEKIVCIAFGGDDSLIFS 189
Mayoviridae_RdRp cd23256
RNA-dependent RNA polymerase (RdRp) in the family Mayoviridae of positive-sense ...
426-725 2.23e-65

RNA-dependent RNA polymerase (RdRp) in the family Mayoviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Mayoviridae, order Martellivirales. The Mayoviridae family consists of two genera, Idaeovirus and Pteridovirus. The genus Idaeovirus contains Raspberry bushy dwarf virus (RBDV), named after the host with which it was first associated (red raspberry, Rubus idaeu) and the disease which is characterized by bushiness (stunting and proliferation of canes); RBDV has recently been found causing an infection in grapevines. RBDV occurs in all tissues of the plant, including seed and pollen, and is transmitted in association with pollen, both vertically to the seed and horizontally to the pollinated plant; this is the only known method of natural spread of RBDV. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438106  Cd Length: 329  Bit Score: 221.54  E-value: 2.23e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 426 DDLPDLNAENLQFYEHMVKSDVKPSVTDTLNIDRPLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGK---I 502
Cdd:cd23256  22 NDPVVLALTSLNKYSHMIKRDRKPVLTTAVQSEYTKAATITYHDKDITQVATPIFRQFKTRLLACKKSNLCIPLDHdhdI 101
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 503 SSLEIKDF--SVLNKFcLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRT 580
Cdd:cd23256 102 SGWLTNRHlgSENGTF-TEIDFSKFDKSQGELHQLIQDLILLRFGCDPEFVSLWSTAHRSSSIKDQNVGISFKTDFQRRT 180
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 581 GDAFTYFGNTLVTMSMFAWCYDTSQFDKLIF---SGDDSLGFSIKAPVGDPSLFTSLFNMEAKVMEPSVPYICSKFLLtd 657
Cdd:cd23256 181 GDAFTFLGNSLVTAVMLAYVLSFEDEKKIRYmlvGGDDSLICSYGPISVPLEPLSTIFNMSCKLIQPSCPYFASRYII-- 258
                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17978218 658 DFGNTF-SVPDPLREIQRLGSKKIPLDEDdrSLHAHFMSFVDRLKFLnhMNQTSMTQLSLFYEMKYRKS 725
Cdd:cd23256 259 RVGDEIlCVPDPYKLLVKMGRKDIPDNEA--SLEEVRTGLADSAKPL--FDDEVKQKLSILVQIRYNKS 323
Closteroviridae_RdRp cd23253
RNA-dependent RNA polymerase (RdRp) in the family Closteroviridae of positive-sense ...
442-698 4.10e-54

RNA-dependent RNA polymerase (RdRp) in the family Closteroviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Closteroviridae, order Martellivirales. Viruses in the family Closteroviridae have a mono-, bi- or tripartite (+)ssRNA genome of 13-19 kb, and non-enveloped, filamentous particles 650-2200 nm long and 12 nm in diameter. They infect plants, mainly dicots, many of which are fruit crops. Members of the family are classified into four genera: Ampelovirus, Closterovirus, Crinivirus and Velarivirus. Their genetic diversity is primarily influenced by strong negative selection and recombination. Closteroviridae viruses are mostly phloem-restricted and induce specific cytoplasmic aggregates of virus particles intermingled with membranous vesicles derived from the endoplasmic reticulum and possibly mitochondria. Their transmission is by aphids, whiteflies, pseudococcid mealybugs or soft scale insects in a semi-persistent manner. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438103  Cd Length: 266  Bit Score: 188.15  E-value: 4.10e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 442 MVKSDVKPSVTDTLNIDRPLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILpvgkISSLEIKDFSVLNK------ 515
Cdd:cd23253   6 MVKGDMKPKLDSSSLSKYPPGQNIVYHERAINAFFSPIFLEVFDRIKYCLSDKIIL----YSGMNLEELASLIRsklgdp 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 516 ----FCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWW--CDFHRMSYIKDKraGVSMPISFQRRTGDAFTYFGN 589
Cdd:cd23253  82 ldeyKTVEIDFSKFDKSQGVLFKVYEELVYKFFGFSEELYDNWkcSEYFSCRATSDS--GVSLELGAQRRTGSPNTWLGN 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 590 TLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAPVGDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDfGNTFSVPDPL 669
Cdd:cd23253 160 TLVTLGILSSSYDLDDIDLLLVSGDDSLIFSKKPLPNKANEINLDFGFEAKFIENSVPYFCSKFIIEDR-GKIKVVPDPV 238
                       250       260
                ....*....|....*....|....*....
gi 17978218 670 REIQRLGsKKIPLDEDDrSLHAHFMSFVD 698
Cdd:cd23253 239 KLFEKLS-VPIRLEDET-LLKERFTSFKD 265
Virgaviridae_RdRp cd23251
RNA-dependent RNA polymerase (RdRp) in the family Virgaviridae of positive-sense ...
315-704 4.12e-53

RNA-dependent RNA polymerase (RdRp) in the family Virgaviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Virgaviridae, order Martellivirales. The Virgaviridae is a family of plant viruses with rod-shaped virions, a (+)ssRNA genome with a 3'-terminal tRNA-like structure and a replication protein similar to those of the alpha-like supergroup. Plants serve as natural hosts. The name of the family is derived from the Latin word virga (rod), as all viruses in this family are rod-shaped. There are currently 59 species in this family, divided among seven genera: Goravirus, Furovirus, Hordeivirus, Pecluvirus, Pomovirus, Tobamovirus, and Tobravirus. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438101  Cd Length: 427  Bit Score: 190.52  E-value: 4.12e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 315 DYSVDIDRVRLKQSDLLAKVIDEGHLKPVLNTGSGQKRIGTTREVLCAIKKRNADVPELCGSVNLKRLSDDVAECFMLSF 394
Cdd:cd23251  20 DINLNVEDCTLDPSKSVKVWQEKEGLKPVLRTAMPEKRQNGLLESLLALIKRNMAAPKLQGAVNEFETIERVIKKAKDVF 99
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 395 MNGDKLcSSNFINIVSDFHAYMSKwQSV------LSYD---DLPDLNAenlqfYEHMVKSDVKPSVTDTLNIDRPLPATI 465
Cdd:cd23251 100 FDEDLI-DRSPLSTRESFLRWWDK-QSTtaraqlLADDrvlDEIDVCT-----YNFMIKNDVKPKLDLSPQSEYAALQTV 172
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 466 TFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSlEIKDF-----SVLNKFCLEIDLSKFDKSQGELHLMIQEGI 540
Cdd:cd23251 173 VYPDKIVNALFGPIFKEINERILSALDPHVVFNTRMTAE-ELNETvefldPDEEYDALEIDFSKFDKSKTSLHIRAVIEL 251
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 541 LNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFS 620
Cdd:cd23251 252 YKLFGLDGMLAFLWEKSQCQTTVKDRQNGIKAYLLYQQKSGNCDTYGSNTWSAALALLSMLPLEKAIFMIFGGDDSLILF 331
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 621 IKA-PVGDP-SLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNTFsVPDPLREIQRLGSKKIpldEDDRSLHAHFMSFVD 698
Cdd:cd23251 332 PKGlVIPDPcRRLASLWNFECKLFKFKYGYFCGKFLLKHGDGYIF-YPDPLKLITKLGRKDI---KDGEHLSEIFVSICD 407

                ....*.
gi 17978218 699 RLKFLN 704
Cdd:cd23251 408 NYKSYR 413
Kitaviridae_RdRp cd23254
catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the family Kitaviridae of ...
439-676 6.04e-48

catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the family Kitaviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the catalytic core domain of RdRp of RNA viruses belonging to the family Kitaviridae, order Martellivirales. The family Kitaviridae is composed of five recognized species among the three genera: Blueberry necrotic ring blotch virus and Tea plant necrotic ring blotch virus (genus Blunervirus); Citrus leprosis virus C and Citrus leprosis virus C2 (genus Cilevirus); and Hibiscus green spot virus 2 (genus Higrevirus). Although related, there are considerable physical and genetic distinctions between members of the different genera. For example, cile- and higreviruses are associated with a bacilliform virion, whereas a spherical virion has been observed for the lone blunervirus for which microscopy has been reported. Moreover, the replication-associated polyproteins are encoded by a single genomic RNA for cile- and higreviruses, but are split between two genomic RNAs for blunerviruses. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438104  Cd Length: 267  Bit Score: 171.18  E-value: 6.04e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 439 YEHMVKSDVKPSVTDTlNIDR-PLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILpvgkISSLEIKDF-SVLN-- 514
Cdd:cd23254   3 YSFMIKRNPKPNLTVD-AAYKyPALQTIAYHDKDINAIFCPIFRELKKRLLAVLKPNFVI----FTDMSPEDFeELLNrr 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 515 ---------KFCLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFT 585
Cdd:cd23254  78 fppevlsklLHKLEIDISKYDKSQGELALLFECKLMRRFGVPEELVELWFNAHVLTTLYDRTNKLKALVEYQRKSGDAST 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 586 YFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSLGFSIKAPV-GDPSLFTSLFNMEAKVMEPSVPYICSKFLLTDDFGNTFs 664
Cdd:cd23254 158 FFGNTLFLMAVLADLFDLSDLELALFSGDDSLLFGRNLLDyDDSQHFALKFNLESKFLNYKYPYFCSKFLLPVGGRWYF- 236
                       250
                ....*....|..
gi 17978218 665 VPDPLREIQRLG 676
Cdd:cd23254 237 VPDPVKLLTKLG 248
ps-ssRNAv_Alsuviricetes_RdRp cd23182
catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the class Alsuviricetes of ...
439-617 8.04e-17

catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the class Alsuviricetes of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the catalytic core domain of RdRp of RNA viruses belonging to the class Alsuviricetes, phylum: Kitrinoviricota. Alsuviricetes is a class of [(+)ssRNA] viruses which infect eukaryotes. The name of the group is a syllabic abbreviation of "alpha supergroup" with the suffix -viricetes indicating a virus class. The class Alsuviricetes includes three orders: Hepelivirales, Martellivirales, and Tymovirales. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438032 [Multi-domain]  Cd Length: 187  Bit Score: 79.18  E-value: 8.04e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 439 YEHMVKSDVKPSVTDTLNIDRPLpATITFHRKQLTSQFSPLFtalfqRFQRCLTKRVILPVGKISSLEIKDFSVLNKFC- 517
Cdd:cd23182   3 IDFLIKTQQKVSPKTPFNTGKAG-QTIAAHSKSINFVLGPWI-----RYLEERLRDGSRTHRYSNGLMDEEEAMLSQWKi 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 518 --------LEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKWWCDFHRMSYIKDKRAGVSMPISFQRRTGDAFTYFGN 589
Cdd:cd23182  77 nhvphatfVSNDYTAFDKSHNGESLLLEAAIMRRIGTPAAAPNLFIELHGKRTLRAKVLGGSGELDGMRDSGAAWTYCRN 156
                       170       180       190
                ....*....|....*....|....*....|..
gi 17978218 590 TLVTMsmfawCYDTSQFDKLI----FSGDDSL 617
Cdd:cd23182 157 TDYNL-----AVMLSLYRLKVkpaaFSGDDSL 183
ps-ssRNAv_Hepelivirales_RdRp cd23209
catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the order Hepelivirales of ...
465-617 7.98e-09

catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the order Hepelivirales of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the catalytic core domain of RdRp of RNA viruses belonging to the order Hepelivirales, class Alsuviricetes. This Hepelivirales order consists of four families: Alphatetraviridae, Benyviridae, Hepeviridae, and Matonaviridae. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438059 [Multi-domain]  Cd Length: 183  Bit Score: 55.96  E-value: 7.98e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 465 ITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEI-KDFSVLNKFCLEIDLSKFDKSQGELHLMIQEGILNR 543
Cdd:cd23209  28 ISAWSKELCFVFGPWFRALEKILRRALKPNVLYANGHEAEPFVdKINQAHSAVFIENDFTEFDSTQNLFSLLVELEILEA 107
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17978218 544 LGCPVHISKWWCDFhRMSYIKDKRaGVSMPISFQRRTGDAFTYFGNTLVTMSMFAWCYDTSQFDKLIFSGDDSL 617
Cdd:cd23209 108 CGMPPALAELYRAL-RAKWTLQAR-EGSLEGTCKKTSGEPGTLLHNTIWNMAVMMHMVRGGVRKAAAFKGDDSV 179
Gammaflexiviridae_RdRp cd23249
RNA-dependent RNA polymerase (RdRp) in the family Gammaflexiviridae of positive-sense ...
441-617 1.48e-08

RNA-dependent RNA polymerase (RdRp) in the family Gammaflexiviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses, in the order Tymovirales; This group contains the RdRp of RNA viruses belonging to the family Gammaflexiviridae, order Tymovirales. Virions within the Gammaflexiviridae family are flexuous filaments of 720 nm modal length and about 13 nm in diameter. Members of the Tymovirales order are mainly plant pathogens that are characterized by similarities in their replication-associated polyproteins, which account for the majority of their genomic coding capacity. They are considered to form a group, phylogenetically, referred to as flexiviruses, with filamentous virions. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438099  Cd Length: 354  Bit Score: 57.61  E-value: 1.48e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 441 HMVKSDVK-PSVT--DTLNIDRPLPATITFHRKQLTSQFSPLFTALFQRFQRCLTKRVILPVGKISSLEIKDFSVLNKF- 516
Cdd:cd23249  71 HMIELFIKgQTVTklGKMGSDATAGQSIASFRAQVLLAWGPLARYLDRRIRALLPPHIYIHSGRTNEDFERFVAAHWDFt 150
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 517 --CLEIDLSKFDKSQGELHLMIQEGILNRLGCPVHISKwwcdfhrmSYIKDKRAGVSM--PISFQRRTGDAFTYFGNTLV 592
Cdd:cd23249 151 reSTEGDYTAFDASQDADFLNFETLLMRALGVPLDLIE--------AYLEMKASITSHlgPLAIMRFSGEVWTYLFNTLG 222
                       170       180
                ....*....|....*....|....*
gi 17978218 593 TMSMFAWCYDTSQFDKLIFSGDDSL 617
Cdd:cd23249 223 NMAYTAAKYEVPPPVPRVYGGDDKS 247
Endornaviridae_RdRp cd23255
catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the family Endornaviridae of ...
465-620 3.19e-07

catalytic core domain of RNA-dependent RNA polymerase (RdRp) in the family Endornaviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the catalytic core domain of RdRp of RNA viruses belonging to the family Endornaviridae, order Martellivirales. The family Endornaviridae includes viruses with linear (+)ssRNA genomes that range from 9.7 to 17.6 kb. The family consists of two genera, Alphaendornavirus and Betaendornavirus. Alphaendornavirus includes species whose members infect plants, fungi and oomycetes, while the genus Betaendornavirus includes species whose members infect ascomycete fungi. Plant endornaviruses are transmitted only through the gametes. A conserved RNA-dependent RNA polymerase domain located in the C-terminal region of the polyprotein is a feature common to all endornaviruses. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438105  Cd Length: 237  Bit Score: 52.15  E-value: 3.19e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 465 ITFHRKQLTSQFSPLFTALFQRFQRCLTKRVI----LPVGKISSLeIKDFSVlNKFCLEIDLSKFDKsQGELHLM-IQEG 539
Cdd:cd23255  61 IVWQRKGICAIFSPIFNEAKKRLKSLLKPKVVyadgLTPDELSAR-LRLVKN-VKYFFEDDLSKQDR-QTDKPIIdVEME 137
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 540 ILNRLG-CPVHISKW-WCDFH---RMSYIKdkraGVSmpiSFQRRTGDAFTYFGNTLVTMSMFAWCYDT--SQFDKLIFS 612
Cdd:cd23255 138 LYKLLGvDPNVIELWrEVHENwrfKGKGVR----GVG---DAMRLTGQATTALGNVITNLLVHSRLVKRngSNLKLMLVL 210

                ....*...
gi 17978218 613 GDDSLGFS 620
Cdd:cd23255 211 GDDNLILT 218
Togaviridae_RdRp cd23250
RNA-dependent RNA polymerase (RdRp) in the family Togaviridae of positive-sense ...
518-750 1.93e-04

RNA-dependent RNA polymerase (RdRp) in the family Togaviridae of positive-sense single-stranded RNA [(+)ssRNA] viruses; This group contains the RdRp of RNA viruses belonging to the family Togaviridae, order Martellivirales. Togaviridae is a family of small, enveloped viruses with [(+)ssRNA] genomes of 10-12 kb, and contains a single genus, Alphavirus. Alphavirus includes a large number of species that are mostly mosquito-borne and pathogenic in their vertebrate hosts. Many are important human and veterinary pathogens (e.g., chikungunya virus, eastern equine encephalitis virus). The genus Alphavirus mainly consists of mosquito-borne viruses although other hematophagous insects, including ticks, lice, and cliff swallow bugs, have been implicated in transmission. Vertebrate hosts include humans, non-human primates, equids, birds, amphibians, reptiles, rodents, and pigs. There are two aquatic alphaviruses, southern elephant seal virus and salmon pancreas disease virus, infecting sea mammals and fish respectively. Interestingly, Eilat virus (EILV) has been shown to only infect insect cells and is incapable of replicating in vertebrate cells. The RdRp domain displays a right hand with three functional subdomains, called fingers, palm, and thumb. All RdRps contain conserved polymerase motifs (A-G), located in the palm (A-E motifs) and finger (F-G) subdomains. All these motifs have been implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides.


Pssm-ID: 438100  Cd Length: 458  Bit Score: 44.76  E-value: 1.93e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 518 LEIDLSKFDKSQGE----LHLMIQE--GILNRLGCPVHISkwwcdFHRMSYIKdKRAGVSMPISFQRRTGDAFTYFGNTL 591
Cdd:cd23250 218 LETDIASFDKSQDDamalTALMILEdlGVDQELLDLIEAA-----FGEITSVH-LPTGTRFKFGAMMKSGMFLTLFVNTV 291
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 592 VTMSMFAWCYDTSQFDK--LIFSGDDSLgfsIKAPVGDPSLF---TSLFNMEAKVMEPSV----PYICSKFLLTDDFGNT 662
Cdd:cd23250 292 LNIVIASRVLRERLTNSrcAAFIGDDNI---VHGVVSDKLMAdrcATWLNMEVKIIDAVIgekpPYFCGGFILYDSVTGT 368
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17978218 663 FS-VPDPLREIQRLGsKKIPLDEDD-----RSLHahfmsfvDRLKFLNHMNQTSMTQLSLfyEMKYRKSG-DDILLVLGA 735
Cdd:cd23250 369 ACrVADPLKRLFKLG-KPLPADDEQdedrrRALH-------DEVKRWFRVGITSELEVAV--ESRYEVNGlSNILLAMAT 438
                       250
                ....*....|....*....
gi 17978218 736 FNKYTANFNA----YKELY 750
Cdd:cd23250 439 LAQSVKNFKAlrgpPIHLY 457
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH