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Conserved domains on  [gi|1898670300|emb|CAD1807835|]
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late protein L1 [human papillomavirus 73]

Protein Classification

major capsid protein L1( domain architecture ID 10010233)

major capsid protein L1 forms an icosahedral capsid with a 50 nm diameter; the capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-502 0e+00

major capsid L1 protein; Provisional


:

Pssm-ID: 222928  Cd Length: 503  Bit Score: 997.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300   1 MWRPTDAKVYLPPVSVSKVVSTDEYVTRTNIYYYAGSTRLLAVGHPYFPIKDSQKRKTIVPKVSGLQYRVFRLRLPDPNK 80
Cdd:PHA02778    3 LWLPSSGKLYLPPTPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNKVTVPKVSGNQYRVFRVKLPDPNK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300  81 FGFPDASFYNPDKERLVWACSGVEVGRGQPLGIGTSGNPFMNKLDDTENAPKYIAGQNTDGRECMSVDYKQTQLCILGCR 160
Cdd:PHA02778   83 FALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGCT 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 161 PPLGEHWGPGTPCTSQTVNTGDCPPLELKNTPIQDGDMIDVGFGAMDFKALQANKSDVPIDISNTTCKYPDYLGMAADPY 240
Cdd:PHA02778  163 PALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDPY 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 241 GDSMWFYLRREQMFVRHLFNRAGDTGDKIPDELMIKGTGNTA-TPSSCVFYPTPSGSMVSSDAQLFNKPYWLQKAQGQNN 319
Cdd:PHA02778  243 GDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAqTLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHNN 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 320 GICWHNQLFLTVVDTTRSTNFSVCVGTQAsSSTTTYANSNFKEYLRHAEEYDLQFVFQLCKISLTTEVMTYIHSMNSTIL 399
Cdd:PHA02778  323 GICWNNQLFVTVVDNTRNTNFTISVKTDE-TPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 400 EEWNFGLTPPPSGTLEETYRYVTSQAISCQRPQPPKETDDPYAKLSFWDVDLKEKFSAELDQFPLGRKFLLQLGMRARPK 479
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|...
gi 1898670300 480 LQASKRSASaTTSATPKKKRAKR 502
Cdd:PHA02778  482 RRKRKSTSS-SSSRSTKRRRRKR 503
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-502 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 997.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300   1 MWRPTDAKVYLPPVSVSKVVSTDEYVTRTNIYYYAGSTRLLAVGHPYFPIKDSQKRKTIVPKVSGLQYRVFRLRLPDPNK 80
Cdd:PHA02778    3 LWLPSSGKLYLPPTPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNKVTVPKVSGNQYRVFRVKLPDPNK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300  81 FGFPDASFYNPDKERLVWACSGVEVGRGQPLGIGTSGNPFMNKLDDTENAPKYIAGQNTDGRECMSVDYKQTQLCILGCR 160
Cdd:PHA02778   83 FALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGCT 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 161 PPLGEHWGPGTPCTSQTVNTGDCPPLELKNTPIQDGDMIDVGFGAMDFKALQANKSDVPIDISNTTCKYPDYLGMAADPY 240
Cdd:PHA02778  163 PALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDPY 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 241 GDSMWFYLRREQMFVRHLFNRAGDTGDKIPDELMIKGTGNTA-TPSSCVFYPTPSGSMVSSDAQLFNKPYWLQKAQGQNN 319
Cdd:PHA02778  243 GDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAqTLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHNN 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 320 GICWHNQLFLTVVDTTRSTNFSVCVGTQAsSSTTTYANSNFKEYLRHAEEYDLQFVFQLCKISLTTEVMTYIHSMNSTIL 399
Cdd:PHA02778  323 GICWNNQLFVTVVDNTRNTNFTISVKTDE-TPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 400 EEWNFGLTPPPSGTLEETYRYVTSQAISCQRPQPPKETDDPYAKLSFWDVDLKEKFSAELDQFPLGRKFLLQLGMRARPK 479
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|...
gi 1898670300 480 LQASKRSASaTTSATPKKKRAKR 502
Cdd:PHA02778  482 RRKRKSTSS-SSSRSTKRRRRKR 503
Late_protein_L1 pfam00500
L1 (late) protein;
2-501 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 866.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300   2 WRPTDAKVYLPPVSVSKVVSTDEYVTRTNIYYYAGSTRLLAVGHPYFPIKDSqKRKTIVPKVSGLQYRVFRLRLPDPNKF 81
Cdd:pfam00500   1 WLPSQQKLYLPPQPVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKGR-NDKVLVPKVSGNQYRVFRLKLPDPNRF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300  82 GFPDASFYNPDKERLVWACSGVEVGRGQPLGIGTSGNPFMNKLDDTENAPKYIAGQNTDGRECMSVDYKQTQLCILGCRP 161
Cdd:pfam00500  80 ALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQGGDNRQNMAFDPKQTQMFIVGCTP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 162 PLGEHWGPGTPCTSQTVNTGDCPPLELKNTPIQDGDMIDVGFGAMDFKALQANKSDVPIDISNTTCKYPDYLGMAADPYG 241
Cdd:pfam00500 160 AIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAEDPYG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 242 DSMWFYLRREQMFVRHLFNRAGDTGDKIPDELMIKG-TGNTATPSSCVFYPTPSGSMVSSDAQLFNKPYWLQKAQGQNNG 320
Cdd:pfam00500 240 DSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKGaGEEQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQGHNNG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 321 ICWHNQLFLTVVDTTRSTNFSVCVGTQASSStTTYANSNFKEYLRHAEEYDLQFVFQLCKISLTTEVMTYIHSMNSTILE 400
Cdd:pfam00500 320 ICWNNQLFVTVVDNTRGTNFTISVKADENDE-TTYDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHTMNPSILE 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 401 EWNFGLTPPPSGTLEETYRYVTSQAISCQRPQPPKETDDPYAKLSFWDVDLKEKFSAELDQFPLGRKFLLQLGMRARPKl 480
Cdd:pfam00500 399 DWNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSGLTQSSS- 477

                         490       500
                  ....*....|....*....|.
gi 1898670300 481 qASKRSASATTSATPKKKRAK 501
Cdd:pfam00500 478 -STKRKAPASVAVSRSSKRKR 497
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-502 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 997.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300   1 MWRPTDAKVYLPPVSVSKVVSTDEYVTRTNIYYYAGSTRLLAVGHPYFPIKDSQKRKTIVPKVSGLQYRVFRLRLPDPNK 80
Cdd:PHA02778    3 LWLPSSGKLYLPPTPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNKVTVPKVSGNQYRVFRVKLPDPNK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300  81 FGFPDASFYNPDKERLVWACSGVEVGRGQPLGIGTSGNPFMNKLDDTENAPKYIAGQNTDGRECMSVDYKQTQLCILGCR 160
Cdd:PHA02778   83 FALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGCT 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 161 PPLGEHWGPGTPCTSQTVNTGDCPPLELKNTPIQDGDMIDVGFGAMDFKALQANKSDVPIDISNTTCKYPDYLGMAADPY 240
Cdd:PHA02778  163 PALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDPY 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 241 GDSMWFYLRREQMFVRHLFNRAGDTGDKIPDELMIKGTGNTA-TPSSCVFYPTPSGSMVSSDAQLFNKPYWLQKAQGQNN 319
Cdd:PHA02778  243 GDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAqTLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHNN 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 320 GICWHNQLFLTVVDTTRSTNFSVCVGTQAsSSTTTYANSNFKEYLRHAEEYDLQFVFQLCKISLTTEVMTYIHSMNSTIL 399
Cdd:PHA02778  323 GICWNNQLFVTVVDNTRNTNFTISVKTDE-TPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 400 EEWNFGLTPPPSGTLEETYRYVTSQAISCQRPQPPKETDDPYAKLSFWDVDLKEKFSAELDQFPLGRKFLLQLGMRARPK 479
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|...
gi 1898670300 480 LQASKRSASaTTSATPKKKRAKR 502
Cdd:PHA02778  482 RRKRKSTSS-SSSRSTKRRRRKR 503
Late_protein_L1 pfam00500
L1 (late) protein;
2-501 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 866.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300   2 WRPTDAKVYLPPVSVSKVVSTDEYVTRTNIYYYAGSTRLLAVGHPYFPIKDSqKRKTIVPKVSGLQYRVFRLRLPDPNKF 81
Cdd:pfam00500   1 WLPSQQKLYLPPQPVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKGR-NDKVLVPKVSGNQYRVFRLKLPDPNRF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300  82 GFPDASFYNPDKERLVWACSGVEVGRGQPLGIGTSGNPFMNKLDDTENAPKYIAGQNTDGRECMSVDYKQTQLCILGCRP 161
Cdd:pfam00500  80 ALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQGGDNRQNMAFDPKQTQMFIVGCTP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 162 PLGEHWGPGTPCTSQTVNTGDCPPLELKNTPIQDGDMIDVGFGAMDFKALQANKSDVPIDISNTTCKYPDYLGMAADPYG 241
Cdd:pfam00500 160 AIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAEDPYG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 242 DSMWFYLRREQMFVRHLFNRAGDTGDKIPDELMIKG-TGNTATPSSCVFYPTPSGSMVSSDAQLFNKPYWLQKAQGQNNG 320
Cdd:pfam00500 240 DSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKGaGEEQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQGHNNG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 321 ICWHNQLFLTVVDTTRSTNFSVCVGTQASSStTTYANSNFKEYLRHAEEYDLQFVFQLCKISLTTEVMTYIHSMNSTILE 400
Cdd:pfam00500 320 ICWNNQLFVTVVDNTRGTNFTISVKADENDE-TTYDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHTMNPSILE 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1898670300 401 EWNFGLTPPPSGTLEETYRYVTSQAISCQRPQPPKETDDPYAKLSFWDVDLKEKFSAELDQFPLGRKFLLQLGMRARPKl 480
Cdd:pfam00500 399 DWNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSGLTQSSS- 477

                         490       500
                  ....*....|....*....|.
gi 1898670300 481 qASKRSASATTSATPKKKRAK 501
Cdd:pfam00500 478 -STKRKAPASVAVSRSSKRKR 497
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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