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Conserved domains on  [gi|42557814|emb|CAD27775|]
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ccdB [Cloning vector pTarg1]

Protein Classification

type II toxin-antitoxin system toxin CcdB( domain architecture ID 10014360)

type II toxin-antitoxin (TA) system toxin CcdB is the toxic component of a TA system that functions in plasmid maintenance; it is responsible for the post-segregational killing (PSK) of plasmid-free cells and its toxicity is inhibited by labile antitoxin CcdA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
1-84 7.27e-56

type II toxin-antitoxin system toxin CcdB;


:

Pssm-ID: 184264  Cd Length: 101  Bit Score: 167.33  E-value: 7.27e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42557814    1 MDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 80
Cdd:PRK13708  18 VDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESYRLMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 97


                 ....
gi 42557814   81 FWGI 84
Cdd:PRK13708  98 FWGI 101
 
Name Accession Description Interval E-value
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
1-84 7.27e-56

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 167.33  E-value: 7.27e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42557814    1 MDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 80
Cdd:PRK13708  18 VDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESYRLMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 97


                 ....
gi 42557814   81 FWGI 84
Cdd:PRK13708  98 FWGI 101
CcdB pfam01845
CcdB protein;
1-82 4.59e-35

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 114.56  E-value: 4.59e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42557814    1 MDVQSDIIDTPGRRMVIPLASARLLSDKVSReLYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 80
Cdd:pfam01845 19 LDVQSDLLDDLNTRVVIPLLPLSAFPKPPRR-LNPVFEVEGESYVLMTPEMASVPARLLGKPVASLSEHRDEIIAALDFL 97


                 ..
gi 42557814   81 FW 82
Cdd:pfam01845 98 FT 99
 
Name Accession Description Interval E-value
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
1-84 7.27e-56

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 167.33  E-value: 7.27e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42557814    1 MDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 80
Cdd:PRK13708  18 VDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESYRLMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 97


                 ....
gi 42557814   81 FWGI 84
Cdd:PRK13708  98 FWGI 101
CcdB pfam01845
CcdB protein;
1-82 4.59e-35

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 114.56  E-value: 4.59e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42557814    1 MDVQSDIIDTPGRRMVIPLASARLLSDKVSReLYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLM 80
Cdd:pfam01845 19 LDVQSDLLDDLNTRVVIPLLPLSAFPKPPRR-LNPVFEVEGESYVLMTPEMASVPARLLGKPVASLSEHRDEIIAALDFL 97


                 ..
gi 42557814   81 FW 82
Cdd:pfam01845 98 FT 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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