NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2002325642|emb|CAF7697739|]
View 

unnamed protein product, partial [Gephyrocapsa muellerae]

Protein Classification

MON2 family protein( domain architecture ID 10579716)

MON2 family protein may play a role in regulating membrane trafficking of cargo proteins, and may not have guanine nucleotide exchange (GEF) activity

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Sec7_N pfam12783
Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 ...
 24-183 1.17e-20

Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 functions proximally in the secretory pathway as a protein binding scaffold for the coat protein complexes COPII-COPI. The COPII-COPI-protein switch is necessary for maturation of the vesicular-tubular cluster, VTC, intermediate compartments for Golgi compartment biogenesis. This N-terminal domain however does not appear to be binding either of the COP or the ARF.


:

Pssm-ID: 463703  Cd Length: 154  Bit Score: 88.71  E-value: 1.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642  24 AARCAYLAVVDLCDLASGEP-AQWLTGLSSPVPTVFALEVVQRTLASHATLFLGQPDFRHLLHEHVCPLALKCMQHTVQH 102
Cdd:pfam12783   1 AAKDAFLVFRDLCKLSNGKPlSKSDPKSHAERSKLFSLELIESILENHGDVFLKHPELLQLLKQYLCPSLLRNLSSSSFP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642 103 QAVtdwehalRACHLTATLLLSYARAVRTEAEILLVTLGKMLEAEGTPIWQRALVLETFRLLSSDAPLLTAIFTAYDLSP 182
Cdd:pfam12783  81 VFV-------RSLRIFLLLLRRFRSHLKLEIEVFLSLLILPLLESDSSLWQKALVLEVLRRLCSDPQLLVEIYLNYDCDL 153


                  .
gi 2002325642 183 S 183
Cdd:pfam12783 154 G 154
 
Name Accession Description Interval E-value
Sec7_N pfam12783
Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 ...
 24-183 1.17e-20

Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 functions proximally in the secretory pathway as a protein binding scaffold for the coat protein complexes COPII-COPI. The COPII-COPI-protein switch is necessary for maturation of the vesicular-tubular cluster, VTC, intermediate compartments for Golgi compartment biogenesis. This N-terminal domain however does not appear to be binding either of the COP or the ARF.


Pssm-ID: 463703  Cd Length: 154  Bit Score: 88.71  E-value: 1.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642  24 AARCAYLAVVDLCDLASGEP-AQWLTGLSSPVPTVFALEVVQRTLASHATLFLGQPDFRHLLHEHVCPLALKCMQHTVQH 102
Cdd:pfam12783   1 AAKDAFLVFRDLCKLSNGKPlSKSDPKSHAERSKLFSLELIESILENHGDVFLKHPELLQLLKQYLCPSLLRNLSSSSFP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642 103 QAVtdwehalRACHLTATLLLSYARAVRTEAEILLVTLGKMLEAEGTPIWQRALVLETFRLLSSDAPLLTAIFTAYDLSP 182
Cdd:pfam12783  81 VFV-------RSLRIFLLLLRRFRSHLKLEIEVFLSLLILPLLESDSSLWQKALVLEVLRRLCSDPQLLVEIYLNYDCDL 153


                  .
gi 2002325642 183 S 183
Cdd:pfam12783 154 G 154
 
Name Accession Description Interval E-value
Sec7_N pfam12783
Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 ...
 24-183 1.17e-20

Guanine nucleotide exchange factor in Golgi transport N-terminal; The full-length Sec7 functions proximally in the secretory pathway as a protein binding scaffold for the coat protein complexes COPII-COPI. The COPII-COPI-protein switch is necessary for maturation of the vesicular-tubular cluster, VTC, intermediate compartments for Golgi compartment biogenesis. This N-terminal domain however does not appear to be binding either of the COP or the ARF.


Pssm-ID: 463703  Cd Length: 154  Bit Score: 88.71  E-value: 1.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642  24 AARCAYLAVVDLCDLASGEP-AQWLTGLSSPVPTVFALEVVQRTLASHATLFLGQPDFRHLLHEHVCPLALKCMQHTVQH 102
Cdd:pfam12783   1 AAKDAFLVFRDLCKLSNGKPlSKSDPKSHAERSKLFSLELIESILENHGDVFLKHPELLQLLKQYLCPSLLRNLSSSSFP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2002325642 103 QAVtdwehalRACHLTATLLLSYARAVRTEAEILLVTLGKMLEAEGTPIWQRALVLETFRLLSSDAPLLTAIFTAYDLSP 182
Cdd:pfam12783  81 VFV-------RSLRIFLLLLRRFRSHLKLEIEVFLSLLILPLLESDSSLWQKALVLEVLRRLCSDPQLLVEIYLNYDCDL 153


                  .
gi 2002325642 183 S 183
Cdd:pfam12783 154 G 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH