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Conserved domains on  [gi|343429938|emb|CBQ73510|]
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conserved hypothetical protein [Sporisorium reilianum SRZ2]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-228 1.11e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  63 EQVAIAAIELAR-------FDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIA 135
Cdd:COG2956   73 PDRAEALLELAQdylkaglLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 136 AIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAY 215
Cdd:COG2956  153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEAL 232

                        170
                 ....*....|...
gi 343429938 216 KAYLRVLELCQSD 228
Cdd:COG2956  233 ELLRKALELDPSD 245
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-228 1.11e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  63 EQVAIAAIELAR-------FDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIA 135
Cdd:COG2956   73 PDRAEALLELAQdylkaglLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 136 AIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAY 215
Cdd:COG2956  153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEAL 232

                        170
                 ....*....|...
gi 343429938 216 KAYLRVLELCQSD 228
Cdd:COG2956  233 ELLRKALELDPSD 245
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 68-224 5.43e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 5.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938   68 AAIELARFDLAELCISRLTSRF-------PNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKST 140
Cdd:TIGR02917 501 AAANLARIDIQEGNPDDAIQRFekvltidPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  141 GDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:TIGR02917 581 GQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660


                  ....
gi 343429938  221 VLEL 224
Cdd:TIGR02917 661 ALEL 664
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-228 1.11e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  63 EQVAIAAIELAR-------FDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIA 135
Cdd:COG2956   73 PDRAEALLELAQdylkaglLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 136 AIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAY 215
Cdd:COG2956  153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEAL 232

                        170
                 ....*....|...
gi 343429938 216 KAYLRVLELCQSD 228
Cdd:COG2956  233 ELLRKALELDPSD 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-251 3.21e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 59.64  E-value: 3.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  66 AIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKR 145
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 146 TLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLELC 225
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAA 174

                        170       180
                 ....*....|....*....|....*.
gi 343429938 226 QSDRGATDQLTNSKQNAAQGPWLRAL 251
Cdd:COG0457  175 LAALLAAALGEAALALAAAEVLLALL 200
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 100-235 3.25e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 3.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 100 GMLLEGQGKLEQAIELYDDALAKEQTSLiFSRRRIAAI-KSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYA 178
Cdd:COG2956   49 GNLYRRRGEYDRAIRIHQKLLERDPDRA-EALLELAQDyLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWE 127

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 343429938 179 QSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLELCQSDRGATDQL 235
Cdd:COG2956  128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLL 184
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 61-251 4.21e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.78  E-value: 4.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  61 ILEQVAIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEqtslifsrrriaaikst 140
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN----------------- 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 141 gdtkrtldalnahldtfYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:COG3914  143 -----------------PDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRR 205

                        170       180       190
                 ....*....|....*....|....*....|.
gi 343429938 221 VLELCQSDRGATDQLTNSKQNAAQGPWLRAL 251
Cdd:COG3914  206 ALELDPDNADAHSNLLFALRQACDWEVYDRF 236
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 64-194 1.22e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 1.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  64 QVAIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDT 143
Cdd:COG4783    9 ALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 343429938 144 KRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQN 194
Cdd:COG4783   89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 147-224 1.32e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 1.32e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 343429938 147 LDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG4235    3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-224 1.50e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.74  E-value: 1.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  74 RFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKRTLDALNAH 153
Cdd:COG2956   57 EYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL 136

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 343429938 154 LDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG2956  137 LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ 207
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 99-224 1.90e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.50  E-value: 1.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  99 QGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYA 178
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 343429938 179 QSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG4783   90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
90-224 2.07e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 2.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  90 PNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAE 169
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 343429938 170 VYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 60-223 1.40e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.04  E-value: 1.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  60 SILEQVAIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKS 139
Cdd:COG2956  111 EALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLE 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 140 TGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNgFFHLKYAETLYTNGDVAKAYKAYL 219
Cdd:COG2956  191 QGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLE 269


                 ....
gi 343429938 220 RVLE 223
Cdd:COG2956  270 RQLR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 141-252 1.50e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 1.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 141 GDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:COG4783   18 GDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEK 97

                         90       100       110
                 ....*....|....*....|....*....|..
gi 343429938 221 VLELCQSDRGATDQLTNSKQNAAQGPWLRALW 252
Cdd:COG4783   98 ALKLDPEHPEAYLRLARAYRALGRPDEAIAAL 129
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-190 4.49e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 4.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  64 QVAIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDT 143
Cdd:COG2956  149 ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDP 228

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 343429938 144 KRTLDALNAHLDTfYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQ 190
Cdd:COG2956  229 EEALELLRKALEL-DPSDDLLLALADLLERKEGLEAALALLERQLRR 274
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 68-224 5.43e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 5.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938   68 AAIELARFDLAELCISRLTSRF-------PNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKST 140
Cdd:TIGR02917 501 AAANLARIDIQEGNPDDAIQRFekvltidPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  141 GDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:TIGR02917 581 GQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660


                  ....
gi 343429938  221 VLEL 224
Cdd:TIGR02917 661 ALEL 664
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 141-223 6.35e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.52  E-value: 6.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 141 GDTKRTLDALNAHLDTFYND---PEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFF---HLKYAETLYTNGDVAKA 214
Cdd:COG1729    7 GDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKA 86


                 ....*....
gi 343429938 215 YKAYLRVLE 223
Cdd:COG1729   87 RATLEELIK 95
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
141-224 1.06e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.54  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 141 GDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQsAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE-AIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                 ....
gi 343429938 221 VLEL 224
Cdd:COG3063   85 ALEL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 159-224 1.47e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 1.47e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343429938 159 NDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG4235   49 DNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 109-224 4.87e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 4.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 109 LEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVL 188
Cdd:COG5010   36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 343429938 189 LQVPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:COG5010  116 ALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 66-224 6.25e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 6.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938   66 AIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGM-----------------------------LLEG-----QGKLEQ 111
Cdd:TIGR02917 234 ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALvdfqkknyedaretlqdalksapeylpalLLAGaseyqLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  112 AIELYDDALaKEQTSLIFSRRRIAAIK-STGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQ 190
Cdd:TIGR02917 314 AYQYLNQIL-KYAPNSHQARRLLASIQlRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATEL 392

                         170       180       190
                  ....*....|....*....|....*....|....
gi 343429938  191 VPQNGFFHLKYAETLYTNGDVAKAYKAYLRVLEL 224
Cdd:TIGR02917 393 DPENAAARTQLGISKLSQGDPSEAIADLETAAQL 426
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 141-235 2.57e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 2.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 141 GDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVPQNGFFHLKYAETLYTNGDVAKAYKAYLR 220
Cdd:COG2956   22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                         90
                 ....*....|....*
gi 343429938 221 VLELCQSDRGATDQL 235
Cdd:COG2956  102 LLELDPDDAEALRLL 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 90-194 3.70e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.91  E-value: 3.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  90 PNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIAAIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAE 169
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100
                 ....*....|....*....|....*
gi 343429938 170 VYAHQGLYAQSAFALEEVLLQVPQN 194
Cdd:COG4235   94 AAFQQGDYAEAIAAWQKLLALLPAD 118
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
100-218 3.94e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 38.32  E-value: 3.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938 100 GMLLEGQGKLEQAIELYDDALAKEqtslifsrrriaaikstgdtkrtldalnahldtFYNDPEAWQELAEVYAHQGLYAQ 179
Cdd:COG4700   96 ADALLELGRYDEAIELYEEALTGI---------------------------------FADDPHILLGLAQALFELGRYAE 142

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 343429938 180 SAFALEEVLLQVPQ--NGFFHLKYAETLYTNGDVAKAYKAY 218
Cdd:COG4700  143 ALETLEKLIAKNPDfkSSDAHLLYARALEALGDLEAAEAEL 183
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 56-192 4.54e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.25  E-value: 4.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343429938  56 QDLWSILEQVAIAAIELARFDLAELCISRLTSRFPNSQRVTSLQGMLLEGQGKLEQAIELYDDALAKEQTSLIFSRRRIA 135
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 343429938 136 AIKSTGDTKRTLDALNAHLDTFYNDPEAWQELAEVYAHQGLYAQSAFALEEVLLQVP 192
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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