|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
501-681 |
4.52e-36 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 138.16 E-value: 4.52e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 501 KAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVES 580
Cdd:COG0666 96 RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEA 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 581 GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLK 660
Cdd:COG0666 176 GADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTA 255
|
170 180
....*....|....*....|.
gi 311641325 661 GKTPPILKTEGPEIKKEEELL 681
Cdd:COG0666 256 LLLAAAAGAALIVKLLLLALL 276
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
496-646 |
4.20e-30 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 120.83 E-value: 4.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 496 INIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVE 575
Cdd:COG0666 58 LLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVK 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 311641325 576 LLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEK 646
Cdd:COG0666 138 LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEA 208
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
28-320 |
1.77e-29 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 118.90 E-value: 1.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 28 IEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADM 107
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 108 TIVDNEGKGVLFYCIlpTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHdvKDVCLTFLEKGANPNAINSStGRT 187
Cdd:COG0666 81 NAKDDGGNTLLHAAA--RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGN--LEIVKLLLEAGADVNAQDND-GNT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 188 ALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCC 267
Cdd:COG0666 156 PLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 311641325 268 KYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKN 320
Cdd:COG0666 236 KLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTL 288
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
513-660 |
2.91e-29 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 118.13 E-value: 2.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 513 ESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNS 592
Cdd:COG0666 141 EAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGK 220
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 593 TPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLK 660
Cdd:COG0666 221 TALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTL 288
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
25-286 |
8.12e-29 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 116.98 E-value: 8.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 25 KKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAK 104
Cdd:COG0666 31 LLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 105 ADMTIVDNEGKGVLFYCILptKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHdvKDVCLTFLEKGANPNAINSSt 184
Cdd:COG0666 111 ADVNARDKDGETPLHLAAY--NGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN--LEIVKLLLEAGADVNARDND- 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 185 GRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFA 264
Cdd:COG0666 186 GETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAA 265
|
250 260
....*....|....*....|..
gi 311641325 265 DCCKYIAQRGCDLKWKNLDHKT 286
Cdd:COG0666 266 LIVKLLLLALLLLAAALLDLLT 287
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
67-351 |
1.46e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 113.51 E-value: 1.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 67 LLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNST 146
Cdd:COG0666 5 LLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 147 YEGKPIFLRACEDAHdvKDVCLTFLEKGANPNAINSStGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAA 226
Cdd:COG0666 85 DGGNTLLHAAARNGD--LEIVKLLLEAGADVNARDKD-GETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 227 KGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRA 306
Cdd:COG0666 162 ANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 311641325 307 ERIANKLARPGaKNPNPLWALRLHDWSVEREAFLREAFAVLDRGD 351
Cdd:COG0666 242 GADLNAKDKDG-LTALLLAAAAGAALIVKLLLLALLLLAAALLDL 285
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
28-255 |
1.74e-27 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 113.13 E-value: 1.74e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 28 IEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADM 107
Cdd:COG0666 67 LLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADV 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 108 TIVDNEGKGVLFYCILptKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHdvKDVCLTFLEKGANPNAINSStGRT 187
Cdd:COG0666 147 NAQDNDGNTPLHLAAA--NGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH--LEIVKLLLEAGADVNAKDND-GKT 221
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 188 ALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPL 255
Cdd:COG0666 222 ALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
529-621 |
2.76e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.63 E-value: 2.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 529 LMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALidAASINNSTPLNRAIESCRLDTVK 608
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV--NLKDNGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 311641325 609 YLLDIGAKFQLEN 621
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
501-628 |
8.84e-20 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 90.40 E-value: 8.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 501 KAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVES 580
Cdd:COG0666 162 ANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 311641325 581 GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAM 628
Cdd:COG0666 242 GADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
501-586 |
1.41e-17 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 78.23 E-value: 1.41e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 501 KAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKgANVNATDNfLWTPLHFACHAGQQDIVELLVES 580
Cdd:pfam12796 6 KNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEK 83
|
....*.
gi 311641325 581 GALIDA 586
Cdd:pfam12796 84 GADINV 89
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
486-642 |
1.83e-16 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 80.77 E-value: 1.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 486 IDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFA 565
Cdd:COG0666 15 LLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAA 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 311641325 566 CHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDL 642
Cdd:COG0666 95 ARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKL 171
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
189-277 |
1.53e-15 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 72.46 E-value: 1.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 189 LMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAY-NGDVGLisiNGNTPLHYAAMGGFADCC 267
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHaDVNLKD---NGRTALHYAARSGHLEIV 77
|
90
....*....|
gi 311641325 268 KYIAQRGCDL 277
Cdd:pfam12796 78 KLLLEKGADI 87
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
501-685 |
4.33e-15 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 78.47 E-value: 4.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 501 KAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVES 580
Cdd:PHA02874 133 KKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDH 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 581 GA--------------------------LIDAASINN-----STPLNRAIE-SCRLDTVKYLLDIGAKFQLENRKGHSAM 628
Cdd:PHA02874 213 GNhimnkckngftplhnaiihnrsaielLINNASINDqdidgSTPLHHAINpPCDIDIIDILLYHKADISIKDNKGENPI 292
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 311641325 629 DVAKAYADYriIDLIKEKLDNLPKPAENQKLKGKTppILktEGPEIKKEEELLSSIY 685
Cdd:PHA02874 293 DTAFKYINK--DPVIKDIIANAVLIKEADKLKDSD--FL--EHIEIKDNKEFSDFIK 343
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
505-642 |
2.85e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 75.86 E-value: 2.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 505 LASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQ-----QDIVELLVE 579
Cdd:PHA03100 15 VKNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLE 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 311641325 580 SGALIDAASINNSTPLNRAI--ESCRLDTVKYLLDIGAKFQLENRKGHSAMdvaKAYADYRIIDL 642
Cdd:PHA03100 95 YGANVNAPDNNGITPLLYAIskKSNSYSIVEYLLDNGANVNIKNSDGENLL---HLYLESNKIDL 156
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
495-596 |
6.11e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 74.70 E-value: 6.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 495 NINIITKagdlasLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIV 574
Cdd:PHA03100 168 DINAKNR------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIF 241
|
90 100
....*....|....*....|....*.
gi 311641325 575 ELLVESGALIDA----ASINNSTPLN 596
Cdd:PHA03100 242 KLLLNNGPSIKTiietLLYFKDKDLN 267
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
507-664 |
6.72e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 74.61 E-value: 6.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 507 SLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586
Cdd:PHA02874 106 MIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANV 185
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 587 ASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNlpkpaeNQKLKGKTP 664
Cdd:PHA02874 186 KDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRSAIELLINNASIN------DQDIDGSTP 257
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
14-259 |
2.84e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 72.39 E-value: 2.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 14 YKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINglsALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGH 93
Cdd:PHA03100 4 YIVLTKSRIIKVKNIKYIIMEDDLNDYSYKKPVL---PLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 94 ELS-----MEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCL 168
Cdd:PHA03100 81 NLTdvkeiVKLLLEYGANVNAPDNNGITPLLYAISKKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIDLKILK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 169 TFLEKGANPNAINSstgrtalmeasregvVEIvrgILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLIS 248
Cdd:PHA03100 161 LLIDKGVDINAKNR---------------VNY---LLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVN 222
|
250
....*....|.
gi 311641325 249 INGNTPLHYAA 259
Cdd:PHA03100 223 KYGDTPLHIAI 233
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
40-323 |
2.86e-13 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 72.75 E-value: 2.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 40 INYTEPInGLSALHL---ASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELS-MEILAKAKADMTIVDNEGK 115
Cdd:PHA03095 40 VNFRGEY-GKTPLHLylhYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDvIKLLIKAGADVNAKDKVGR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 116 GVLFYCiLPTKR-HYRCALIALEHGADVNNS-TYEGKP--IFLRAcedahdvKDVCL----TFLEKGANPNAiNSSTGRT 187
Cdd:PHA03095 119 TPLHVY-LSGFNiNPKVIRLLLRKGADVNALdLYGMTPlaVLLKS-------RNANVellrLLIDAGADVYA-VDDRFRS 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 188 AL---MEASREGvVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLF--AYNGDVGLISINGNTPLHYAAMGG 262
Cdd:PHA03095 190 LLhhhLQSFKPR-ARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPllIAGISINARNRYGQTPLHYAAVFN 268
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 311641325 263 FADCCKYIAQRGCDLkwknldhktprAVAKEGGFKAASKEIRRAERIANKLARPgaKNPNP 323
Cdd:PHA03095 269 NPRACRRLIALGADI-----------NAVSSDGNTPLSLMVRNNNGRAVRAALA--KNPSA 316
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
527-578 |
6.43e-13 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 63.83 E-value: 6.43e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 311641325 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLV 578
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
496-651 |
1.61e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 70.08 E-value: 1.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 496 INIITKAGDLASLKKAFESGIPVDMKDNYYKTPL--MTACASGNIDVVKFLLEKGANVNATDNflwtplhfachagqqdi 573
Cdd:PHA03100 112 YAISKKSNSYSIVEYLLDNGANVNIKNSDGENLLhlYLESNKIDLKILKLLIDKGVDINAKNR----------------- 174
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 574 VELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAkayADYRIIDLIKEKLDNLP 651
Cdd:PHA03100 175 VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIA---ILNNNKEIFKLLLNNGP 249
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
513-616 |
1.61e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 67.36 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 513 ESGIPVDMKDNYYKTPLMT-ACASGNIDVVKFLLEKGANVNATDNFLWTPLHfACHAGQQ---DIVELLVESGALIDAAS 588
Cdd:PHA03095 71 EAGADVNAPERCGFTPLHLyLYNATTLDVIKLLIKAGADVNAKDKVGRTPLH-VYLSGFNinpKVIRLLLRKGADVNALD 149
|
90 100 110
....*....|....*....|....*....|
gi 311641325 589 INNSTPLNRAIES--CRLDTVKYLLDIGAK 616
Cdd:PHA03095 150 LYGMTPLAVLLKSrnANVELLRLLIDAGAD 179
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
52-143 |
6.17e-11 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 59.36 E-value: 6.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 52 LHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGH-ELSMEILAKAKADMtivDNEGKGVLFYCILptKRHYR 130
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHlEIVKLLLEHADVNL---KDNGRTALHYAAR--SGHLE 75
|
90
....*....|...
gi 311641325 131 CALIALEHGADVN 143
Cdd:pfam12796 76 IVKLLLEKGADIN 88
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
518-664 |
1.22e-10 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 64.66 E-value: 1.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 518 VDMKDNYYKTPLMTACASGNID--VVKFLLEKGANVNATDNFLWTPLH--FACHAGQQDIVELLVESGALIDAASINNST 593
Cdd:PHA03095 110 VNAKDKVGRTPLHVYLSGFNINpkVIRLLLRKGADVNALDLYGMTPLAvlLKSRNANVELLRLLIDAGADVYAVDDRFRS 189
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 311641325 594 PLNRAIESCRLDT--VKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENqkLKGKTP 664
Cdd:PHA03095 190 LLHHHLQSFKPRAriVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPLLIAGISINARN--RYGQTP 260
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
512-615 |
1.35e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 64.52 E-value: 1.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 512 FESGIPVDMKD-NYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASIN 590
Cdd:PHA02878 154 LSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKC 233
|
90 100
....*....|....*....|....*.
gi 311641325 591 NSTPLNRAIESCR-LDTVKYLLDIGA 615
Cdd:PHA02878 234 GNTPLHISVGYCKdYDILKLLLEHGV 259
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
136-287 |
1.64e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 63.83 E-value: 1.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 136 LEHGADVNN-STYEGKPIFLRACEDAHDV--------------------KDVCLTFLEKGANPNAINSSTgRTALMEASR 194
Cdd:PHA02874 55 IKHGADINHiNTKIPHPLLTAIKIGAHDIikllidngvdtsilpipcieKDMIKTILDCGIDVNIKDAEL-KTFLHYAIK 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 195 EGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRG 274
Cdd:PHA02874 134 KGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHG 213
|
170
....*....|...
gi 311641325 275 CDLKWKNLDHKTP 287
Cdd:PHA02874 214 NHIMNKCKNGFTP 226
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
512-634 |
3.88e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 63.16 E-value: 3.88e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 512 FESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFA-CHAGQQDIVELLVESGALIDAASIN 590
Cdd:PHA02876 362 LELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKD 441
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 311641325 591 NSTPLNRAIE-SCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAY 634
Cdd:PHA02876 442 LSTPLHYACKkNCKLDVIEMLLDNGADVNAINIQNQYPLLIALEY 486
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
538-615 |
5.86e-10 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 62.35 E-value: 5.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 538 IDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQ---DIVELLVESGALIDAASINNSTPLNRAIES-CRLDTVKYLLDI 613
Cdd:PHA03095 27 VEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEkvkDIVRLLLEAGADVNAPERCGFTPLHLYLYNaTTLDVIKLLIKA 106
|
..
gi 311641325 614 GA 615
Cdd:PHA03095 107 GA 108
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
537-664 |
7.60e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 61.90 E-value: 7.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 537 NIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAK 616
Cdd:PHA02874 103 EKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAY 182
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 311641325 617 FQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENqklkGKTP 664
Cdd:PHA02874 183 ANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKN----GFTP 226
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
539-646 |
1.64e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 61.05 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 539 DVVKFLLEKGANVNATD-NFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKF 617
Cdd:PHA02878 148 EITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
90 100 110
....*....|....*....|....*....|
gi 311641325 618 QLENRKGHSAMDVAKAYA-DYRIIDLIKEK 646
Cdd:PHA02878 228 DARDKCGNTPLHISVGYCkDYDILKLLLEH 257
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
159-618 |
1.93e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 61.23 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 159 DAHDVKDVCLTFLEKGANPNAI--NSSTGRTALMEASREGVVE----IVRGILERGGEVNAFDNDRHHAAHFAAKGGFFD 232
Cdd:PHA02876 113 NKHKLDEACIHILKEAISGNDIhyDKINESIEYMKLIKERIQQdellIAEMLLEGGADVNAKDIYCITPIHYAAERGNAK 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 233 ILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLdhktpravakeggfkAASKEIRRAERIANK 312
Cdd:PHA02876 193 MVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDL---------------SLLKAIRNEDLETSL 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 313 LARPGAKNPNPLWALR---LHdWSVEREAFLREAFAVLDRGDGSISKN---DFVMVLEERQDYASSEQLAAIahlhekTR 386
Cdd:PHA02876 258 LLYDAGFSVNSIDDCKntpLH-HASQAPSLSRLVPKLLERGADVNAKNikgETPLYLMAKNGYDTENIRTLI------ML 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 387 GGGVNINEFFKGTRyLNKSFVLGSYGPKkkekgmgkkgkkgkfvlplpicVIPeyafprrqdggppyyMIETYKNVTdss 466
Cdd:PHA02876 331 GADVNAADRLYITP-LHQASTLDRNKDI----------------------VIT---------------LLELGANVN--- 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 467 rfNRDHPPEHPIQddsvwyiddSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKT-PLMTacasgnidvVKFLL 545
Cdd:PHA02876 370 --ARDYCDKTPIH---------YAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTnPYMS---------VKTLI 429
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 311641325 546 EKGANVNATDNFLWTPLHFACHAG-QQDIVELLVESGALIDAASINNSTPLNRAIESCRLdtVKYLLDIGAKFQ 618
Cdd:PHA02876 430 DRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAINIQNQYPLLIALEYHGI--VNILLHYGAELR 501
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
46-287 |
7.00e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 59.31 E-value: 7.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 46 INGLSALHLASVSNDIDMVSFLLDLGAHPDVQDrMGCTPTMRAAELGHELsmeILAKAKADMTIVDNEGKGVLFYCIlPT 125
Cdd:PHA02876 209 LDDLSVLECAVDSKNIDTIKAIIDNRSNINKND-LSLLKAIRNEDLETSL---LLYDAGFSVNSIDDCKNTPLHHAS-QA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 126 KRHYRCALIALEHGADVNNSTYEGK-PIFLRAcEDAHDVKDVcLTFLEKGANPNAINSSTgRTALMEASR-EGVVEIVRG 203
Cdd:PHA02876 284 PSLSRLVPKLLERGADVNAKNIKGEtPLYLMA-KNGYDTENI-RTLIMLGADVNAADRLY-ITPLHQASTlDRNKDIVIT 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 204 ILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFA-DCCKYIAQRGCDLKWKNL 282
Cdd:PHA02876 361 LLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPyMSVKTLIDRGANVNSKNK 440
|
....*
gi 311641325 283 DHKTP 287
Cdd:PHA02876 441 DLSTP 445
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
559-611 |
1.38e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.51 E-value: 1.38e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 311641325 559 WTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLL 611
Cdd:pfam13637 2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
481-634 |
1.64e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 57.69 E-value: 1.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 481 DSVWYIDDS--EKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFL 558
Cdd:PHA02875 89 DLGKFADDVfyKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCG 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 559 WTPLHFACHAGQQDIVELLVESGALIDAASINNS-TPLNRAIESCRLDTVKYLLDIGAK----FQLENRKgHSAMDVAKA 633
Cdd:PHA02875 169 CTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCvAALCYAIENNKIDIVRLFIKRGADcnimFMIEGEE-CTILDMICN 247
|
.
gi 311641325 634 Y 634
Cdd:PHA02875 248 M 248
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
18-111 |
3.17e-08 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 51.66 E-value: 3.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 18 QCVRNKDKKQIEKLTKLGYPelINYTEPiNGLSALHLASVSNDIDMVSFLLDlgaHPDVQDRM-GCTPTMRAAELGHELS 96
Cdd:pfam12796 3 LAAKNGNLELVKLLLENGAD--ANLQDK-NGRTALHLAAKNGHLEIVKLLLE---HADVNLKDnGRTALHYAARSGHLEI 76
|
90
....*....|....*
gi 311641325 97 MEILAKAKADMTIVD 111
Cdd:pfam12796 77 VKLLLEKGADINVKD 91
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
510-631 |
4.39e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 56.61 E-value: 4.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 510 KAFESGIPVDMKDNYYKTPLMTACASG-NIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQ-QDIVELLVESGALIDAA 587
Cdd:PHA02876 292 KLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYITPLHQASTLDRnKDIVITLLELGANVNAR 371
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 311641325 588 SINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVA 631
Cdd:PHA02876 372 DYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFA 415
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
505-646 |
6.44e-08 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 54.96 E-value: 6.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 505 LASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALI 584
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 311641325 585 DAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEK 646
Cdd:COG0666 81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEA 142
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
503-624 |
6.87e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 55.38 E-value: 6.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 503 GDLASLKKAFESGIPVDmkDNYYK---TPLMTACASGNIDVVKFLLEKGAN--VNATDNFlwTPLHFACHAGQQDIVELL 577
Cdd:PHA02875 79 GDVKAVEELLDLGKFAD--DVFYKdgmTPLHLATILKKLDIMKLLIARGADpdIPNTDKF--SPLHLAVMMGDIKGIELL 154
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 311641325 578 VESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKG 624
Cdd:PHA02875 155 IDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNG 201
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
516-565 |
1.27e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 48.88 E-value: 1.27e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 311641325 516 IPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFA 565
Cdd:pfam13857 7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
502-577 |
1.48e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 54.90 E-value: 1.48e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 311641325 502 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELL 577
Cdd:PTZ00322 92 SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
527-646 |
1.53e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 54.58 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESG---ALIDAASINN------------ 591
Cdd:PHA02874 37 TPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGvdtSILPIPCIEKdmiktildcgid 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 311641325 592 --------STPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEK 646
Cdd:PHA02874 117 vnikdaelKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEK 179
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
508-599 |
2.08e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 54.12 E-value: 2.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 508 LKKAFESGIPVDMKDNYYKTPLMTACAS-GNIDVVKFLLEKGANVNATDNFL-WTPLHFACHAgqQDIVELLVESGALID 585
Cdd:PHA02878 217 VHILLENGASTDARDKCGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSYILgLTALHSSIKS--ERKLKLLLEYGADIN 294
|
90
....*....|....
gi 311641325 586 AASINNSTPLNRAI 599
Cdd:PHA02878 295 SLNSYKLTPLSSAV 308
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
165-246 |
2.44e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 48.96 E-value: 2.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 165 DVCLTFLEKGANPNaINSSTGRTALMEASREGVVEIVRgILERGGEVNAFDNDRHhAAHFAAKGGFFDILKLLFAYNGDV 244
Cdd:pfam12796 11 ELVKLLLENGADAN-LQDKNGRTALHLAAKNGHLEIVK-LLLEHADVNLKDNGRT-ALHYAARSGHLEIVKLLLEKGADI 87
|
..
gi 311641325 245 GL 246
Cdd:pfam12796 88 NV 89
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
516-555 |
2.49e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 48.96 E-value: 2.49e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 311641325 516 IPVDMKDNYYkTPLMTACASGNIDVVKFLLEKGANVNATD 555
Cdd:pfam12796 53 ADVNLKDNGR-TALHYAARSGHLEIVKLLLEKGADINVKD 91
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
218-269 |
3.94e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 47.27 E-value: 3.94e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 311641325 218 RHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKY 269
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKL 52
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
534-611 |
5.99e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 52.98 E-value: 5.99e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 534 ASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLL 611
Cdd:PTZ00322 91 ASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLS 168
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
544-598 |
9.63e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.19 E-value: 9.63e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 311641325 544 LLEKG-ANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRA 598
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
493-639 |
1.20e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 51.53 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 493 FSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNatDNFL---WTPLHFACHAG 569
Cdd:PHA02875 36 ISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFAD--DVFYkdgMTPLHLATILK 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 570 QQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRI 639
Cdd:PHA02875 114 KLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAI 183
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
20-212 |
1.22e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 51.53 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 20 VRNKDKKQIEKLTKLG-YPELINYTEpinGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSME 98
Cdd:PHA02875 76 VEEGDVKAVEELLDLGkFADDVFYKD---GMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 99 ILAKAKADMTIVDNEGkgvlfycilptkrhYRCALIALEHGAdvnnstyegkpiflracedahdvKDVCLTFLEKGANPN 178
Cdd:PHA02875 153 LLIDHKACLDIEDCCG--------------CTPLIIAMAKGD-----------------------IAICKMLLDSGANID 195
|
170 180 190
....*....|....*....|....*....|....
gi 311641325 179 AINSSTGRTALMEASREGVVEIVRGILERGGEVN 212
Cdd:PHA02875 196 YFGKNGCVAALCYAIENNKIDIVRLFIKRGADCN 229
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
527-556 |
1.45e-06 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 45.36 E-value: 1.45e-06
10 20 30
....*....|....*....|....*....|.
gi 311641325 527 TPLMTACAS-GNIDVVKFLLEKGANVNATDN 556
Cdd:pfam00023 4 TPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
524-553 |
2.85e-06 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 44.17 E-value: 2.85e-06
10 20 30
....*....|....*....|....*....|
gi 311641325 524 YYKTPLMTACASGNIDVVKFLLEKGANVNA 553
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
524-553 |
3.11e-06 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 44.12 E-value: 3.11e-06
10 20 30
....*....|....*....|....*....|
gi 311641325 524 YYKTPLMTACASGNIDVVKFLLEKGANVNA 553
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
204-258 |
3.80e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 44.64 E-value: 3.80e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 311641325 204 ILERGGE-VNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYA 258
Cdd:pfam13857 1 LLEHGPIdLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
505-636 |
5.77e-06 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 50.08 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 505 LASLKKAFESGIPVDM-----KDNYYK--TPLMTACASGNIDVVKFLLEKGANVNAT---DNFLWT-----------PLH 563
Cdd:TIGR00870 101 LLHLLAAFRKSGPLELandqyTSEFTPgiTALHLAAHRQNYEIVKLLLERGASVPARacgDFFVKSqgvdsfyhgesPLN 180
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 311641325 564 FACHAGQQDIVELLVESGALIDAA-SINNstplnraiescrldTVKYLLDIGAKFQLENRK-GHSAMDVAKAYAD 636
Cdd:TIGR00870 181 AAACLGSPSIVALLSEDPADILTAdSLGN--------------TLLHLLVMENEFKAEYEElSCQMYNFALSLLD 241
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
105-286 |
6.40e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 49.49 E-value: 6.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 105 ADMTIVD-NEGKGVLFYciLPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEdaHDVKDVCLTFLEKGANPNAINSs 183
Cdd:PHA02878 158 ADINMKDrHKGNTALHY--ATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVK--HYNKPIVHILLENGASTDARDK- 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 184 TGRTAL-MEASREGVVEIVRGILERGGEVNAFDNDRHHAA-HFAAKGGffDILKLLFAYNGDVGLISINGNTPLHYAAMG 261
Cdd:PHA02878 233 CGNTPLhISVGYCKDYDILKLLLEHGVDVNAKSYILGLTAlHSSIKSE--RKLKLLLEYGADINSLNSYKLTPLSSAVKQ 310
|
170 180
....*....|....*....|....*.
gi 311641325 262 GFA-DCCKYIAQRGCDLKWKNLDHKT 286
Cdd:PHA02878 311 YLCiNIGRILISNICLLKRIKPDIKN 336
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
34-258 |
6.74e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 49.49 E-value: 6.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 34 LGYPELINYTEP-INGLSA-----LHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADM 107
Cdd:PHA02878 17 LKYIEYIDHTENySTSASLipfipLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSINKC 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 108 TIVDNEGKgvlfyciLPTKRHYRCALIA---LEHGADvNNSTYEGKPIFLRACEDAHDVKDVCLtFLEKGANPNAINSST 184
Cdd:PHA02878 97 SVFYTLVA-------IKDAFNNRNVEIFkiiLTNRYK-NIQTIDLVYIDKKSKDDIIEAEITKL-LLSYGADINMKDRHK 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 311641325 185 GRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYA 258
Cdd:PHA02878 168 GNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHIS 241
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
88-244 |
8.12e-06 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 49.48 E-value: 8.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 88 AAELGHELSMEILAKAKADMTIVDNEGKGVLFycILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVC 167
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLH--IAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRI 609
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 311641325 168 LTFLEKGANPNainssTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDV 244
Cdd:PLN03192 610 LYHFASISDPH-----AAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADV 681
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
508-611 |
9.47e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 48.87 E-value: 9.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 508 LKKAFESGIPVDMKDNYYKTPL--MTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALID 585
Cdd:PHA03095 205 VRELIRAGCDPAATDMLGNTPLhsMATGSSCKRSLVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADIN 284
|
90 100
....*....|....*....|....*.
gi 311641325 586 AASINNSTPLNRAIESCRLDTVKYLL 611
Cdd:PHA03095 285 AVSSDGNTPLSLMVRNNNGRAVRAAL 310
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
538-648 |
1.20e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 48.68 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 538 IDVVKFLLEKGANVNATDNFLWTPL-----HFACHAGQQDIVELLVESGALIDAASINNSTPL-----NRAIEScrLDTV 607
Cdd:PHA02798 51 TDIVKLFINLGANVNGLDNEYSTPLctilsNIKDYKHMLDIVKILIENGADINKKNSDGETPLycllsNGYINN--LEIL 128
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 311641325 608 KYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLD 648
Cdd:PHA02798 129 LFMIENGADTTLLDKDGFTMLQVYLQSNHHIDIEIIKLLLE 169
|
|
| PHA02716 |
PHA02716 |
CPXV016; CPX019; EVM010; Provisional |
504-652 |
1.23e-05 |
|
CPXV016; CPX019; EVM010; Provisional
Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 48.75 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 504 DLASLKKAFESGIPVDMKDNYYKTPLMTACASGNI--DVVKFLLEKGANVNATDNFLWTPLHfaCHAGQQDIVELLvesg 581
Cdd:PHA02716 296 DISVVYSFLQPGVKLHYKDSAGRTCLHQYILRHNIstDIIKLLHEYGNDLNEPDNIGNTVLH--TYLSMLSVVNIL---- 369
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 311641325 582 alidAASINNSTplnraiescRLDTVKYLLDIGAKFQLENRKGHSAMD----VAKAYADYRIID-LIKEKLDNLPK 652
Cdd:PHA02716 370 ----DPETDNDI---------RLDVIQCLISLGADITAVNCLGYTPLTsyicTAQNYMYYDIIDcLISDKVLNMVK 432
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
487-659 |
1.33e-05 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 48.71 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 487 DDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFAC 566
Cdd:PLN03192 520 HDDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAI 599
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 567 HAGQQDIVELLVESGALIDAASINNStpLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKA-----YADYRII- 640
Cdd:PLN03192 600 SAKHHKIFRILYHFASISDPHAAGDL--LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAedhvdMVRLLIMn 677
|
170 180
....*....|....*....|.
gi 311641325 641 --DLIKEKLDNLPKPAENQKL 659
Cdd:PLN03192 678 gaDVDKANTDDDFSPTELREL 698
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
136-258 |
1.44e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 48.42 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 136 LEHGADVNNSTYEGKpIFLRACEDAHDVkDVCLTFLEKGANPNaINSSTGRTALMEASREGVVEIVRGILERGGEVNAFD 215
Cdd:PHA02874 111 LDCGIDVNIKDAELK-TFLHYAIKKGDL-ESIKMLFEYGADVN-IEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKD 187
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 311641325 216 NDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYA 258
Cdd:PHA02874 188 NNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNA 230
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
48-94 |
1.67e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.65 E-value: 1.67e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 311641325 48 GLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHE 94
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNV 47
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
515-649 |
2.35e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 47.52 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 515 GIPVDMKDNYYKTPLMTACAS-----GNIDVVKFLLEKGANVNATDNFLWTPLHFACHAG---QQDIVELLVESGALIDA 586
Cdd:PHA02798 61 GANVNGLDNEYSTPLCTILSNikdykHMLDIVKILIENGADINKKNSDGETPLYCLLSNGyinNLEILLFMIENGADTTL 140
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 587 ASINNSTPLNRAIES---CRLDTVKYLLDIGAKF-QLENRKGHSAMDVAKAYADYRI-IDLIKEKLDN 649
Cdd:PHA02798 141 LDKDGFTMLQVYLQSnhhIDIEIIKLLLEKGVDInTHNNKEKYDTLHCYFKYNIDRIdADILKLFVDN 208
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
526-595 |
2.40e-05 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 47.70 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 526 KTPLMTACASGNIDVVKFLLEKGANVN---AT--------DNFLW---TPLHFACHAGQQDIVELLVESGALIDAASINN 591
Cdd:cd22192 90 ETALHIAVVNQNLNLVRELIARGADVVsprATgtffrpgpKNLIYygeHPLSFAACVGNEEIVRLLIEHGADIRAQDSLG 169
|
....
gi 311641325 592 STPL 595
Cdd:cd22192 170 NTVL 173
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
501-545 |
2.66e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.26 E-value: 2.66e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 311641325 501 KAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLL 545
Cdd:pfam13637 10 ASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
185-237 |
4.89e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.49 E-value: 4.89e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 311641325 185 GRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLL 237
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
529-600 |
1.13e-04 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 45.63 E-value: 1.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 311641325 529 LMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINN---STPLNRAIE 600
Cdd:PLN03192 626 LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKANTDDdfsPTELRELLQ 700
|
|
| PHA02884 |
PHA02884 |
ankyrin repeat protein; Provisional |
506-602 |
1.42e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 44.59 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 506 ASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFL-WTPLHFACHAGQQDIVELLVESGALI 584
Cdd:PHA02884 51 AILKLGADPEAPFPLSENSKTNPLIYAIDCDNDDAAKLLIRYGADVNRYAEEAkITPLYISVLHGCLKCLEILLSYGADI 130
|
90
....*....|....*...
gi 311641325 585 DAASINNSTPLNRAIESC 602
Cdd:PHA02884 131 NIQTNDMVTPIELALMIC 148
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
528-579 |
1.51e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 44.87 E-value: 1.51e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 311641325 528 PLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFAC-HAGQQDIVELLVE 579
Cdd:PHA02878 40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICkEPNKLGMKEMIRS 92
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
20-112 |
2.13e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 44.27 E-value: 2.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 20 VRNKDKkqIEKLTKLGYPelINYTEpINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEI 99
Cdd:PHA03100 169 INAKNR--VNYLLSYGVP--INIKD-VYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKL 243
|
90
....*....|...
gi 311641325 100 LAKAKADMTIVDN 112
Cdd:PHA03100 244 LLNNGPSIKTIIE 256
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
559-586 |
2.68e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.81 E-value: 2.68e-04
10 20
....*....|....*....|....*....
gi 311641325 559 WTPLHFAC-HAGQQDIVELLVESGALIDA 586
Cdd:pfam00023 3 NTPLHLAAgRRGNLEIVKLLLSKGADVNA 31
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
47-79 |
3.05e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.81 E-value: 3.05e-04
10 20 30
....*....|....*....|....*....|....
gi 311641325 47 NGLSALHLASVS-NDIDMVSFLLDLGAHPDVQDR 79
Cdd:pfam00023 1 DGNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
250-277 |
3.84e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.34 E-value: 3.84e-04
10 20
....*....|....*....|....*...
gi 311641325 250 NGNTPLHYAAMGGFADCCKYIAQRGCDL 277
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
50-286 |
4.40e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 43.90 E-value: 4.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 50 SALHLASVSNDID-MVSFLLDLGAHPDVQDRMGCTPTMRAAELGHEL-SMEILAKAKADMTIVDNEGKGVLfYCILPTKR 127
Cdd:PHA02876 275 TPLHHASQAPSLSrLVPKLLERGADVNAKNIKGETPLYLMAKNGYDTeNIRTLIMLGADVNAADRLYITPL-HQASTLDR 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 128 HYRCALIALEHGADVNNSTY-EGKPIFLRACEDAHDVKDvclTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILE 206
Cdd:PHA02876 354 NKDIVITLLELGANVNARDYcDKTPIHYAAVRNNVVIIN---TLLDYGADIEALSQKIGTALHFALCGTNPYMSVKTLID 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 207 RGGEVNAFDNDRHHAAHFAAKGGF-FDILKLLFAYNGDVGLISINGNTPLHYAAmgGFADCCKYIAQRGCDLKWKNLDHK 285
Cdd:PHA02876 431 RGANVNSKNKDLSTPLHYACKKNCkLDVIEMLLDNGADVNAINIQNQYPLLIAL--EYHGIVNILLHYGAELRDSRVLHK 508
|
.
gi 311641325 286 T 286
Cdd:PHA02876 509 S 509
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
520-658 |
4.58e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 43.72 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 520 MKDNYYK--TPLMTACASGNIDVVKFLLEKGANVNATDN-------------FLWTPLHFACHAGQQDIVELLVESGALI 584
Cdd:cd21882 66 CTDEFYQgqTALHIAIENRNLNLVRLLVENGADVSARATgrffrkspgnlfyFGELPLSLAACTNQEEIVRLLLENGAQP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 585 DAASINNS---TPL-------NRAIESCRLDTVKY--LLDIGAKF----QLE---NRKGHSAMDVAKAYADYRIIDLIKE 645
Cdd:cd21882 146 AALEAQDSlgnTVLhalvlqaDNTPENSAFVCQMYnlLLSYGAHLdptqQLEeipNHQGLTPLKLAAVEGKIVMFQHILQ 225
|
170
....*....|...
gi 311641325 646 KLDNLPKPAENQK 658
Cdd:cd21882 226 REFSGPYQPLSRK 238
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
527-643 |
6.75e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 42.67 E-value: 6.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALI-DAASINNSTPLNRAIESCRLD 605
Cdd:PHA02875 37 SPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFAdDVFYKDGMTPLHLATILKKLD 116
|
90 100 110
....*....|....*....|....*....|....*...
gi 311641325 606 TVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLI 643
Cdd:PHA02875 117 IMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELL 154
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
20-149 |
1.13e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 42.26 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 20 VRNKDKKQIEKLTKLGYPELInytEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEI 99
Cdd:PHA02874 132 IKKGDLESIKMLFEYGADVNI---EDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKL 208
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 311641325 100 LAKAKADMTIVDNEGKGVLFYCILptkrHYRCALIALEHGADVNNSTYEG 149
Cdd:PHA02874 209 LIDHGNHIMNKCKNGFTPLHNAII----HNRSAIELLINNASINDQDIDG 254
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
171-240 |
1.16e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 42.19 E-value: 1.16e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 171 LEKGANPNAINSStGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAY 240
Cdd:PTZ00322 102 LTGGADPNCRDYD-GRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
199-287 |
1.57e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 41.79 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 199 EIVRGILERGGEVNAFDNDRHHAA-HFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDL 277
Cdd:PHA02878 148 EITKLLLSYGADINMKDRHKGNTAlHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
90
....*....|
gi 311641325 278 KWKNLDHKTP 287
Cdd:PHA02878 228 DARDKCGNTP 237
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
250-281 |
1.92e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 1.92e-03
10 20 30
....*....|....*....|....*....|...
gi 311641325 250 NGNTPLHYAA-MGGFADCCKYIAQRGCDLKWKN 281
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
250-277 |
1.93e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 36.47 E-value: 1.93e-03
10 20
....*....|....*....|....*...
gi 311641325 250 NGNTPLHYAAMGGFADCCKYIAQRGCDL 277
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADI 28
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
55-275 |
2.21e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 41.13 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 55 ASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKakadmtivdnegkgvlfycilptkrhyrcali 134
Cdd:PHA02875 9 AILFGELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMK-------------------------------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 135 aleHGAdVNNSTYEGKPIFLRACEDAHDVKDVCLtFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAF 214
Cdd:PHA02875 57 ---HGA-IPDVKYPDIESELHDAVEEGDVKAVEE-LLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIP 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 311641325 215 DNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCK----------YIAQRGC 275
Cdd:PHA02875 132 NTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKmlldsganidYFGKNGC 202
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
10-130 |
2.51e-03 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 41.19 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 10 NLQIYKVLQCVRNKDKKQIEKLTKLGYPEliNYTEPiNGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAA 89
Cdd:PHA02946 37 NYHILHAYCGIKGLDERFVEELLHRGYSP--NETDD-DGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLS 113
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 311641325 90 ----ELGHELSMEILAKAKADMTiVDNEGKGVLFYCILPTKRHYR 130
Cdd:PHA02946 114 gtddEVIERINLLVQYGAKINNS-VDEEGCGPLLACTDPSERVFK 157
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
47-76 |
2.94e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 35.70 E-value: 2.94e-03
10 20 30
....*....|....*....|....*....|
gi 311641325 47 NGLSALHLASVSNDIDMVSFLLDLGAHPDV 76
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
47-76 |
3.31e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 35.64 E-value: 3.31e-03
10 20 30
....*....|....*....|....*....|
gi 311641325 47 NGLSALHLASVSNDIDMVSFLLDLGAHPDV 76
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
559-586 |
4.23e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 35.26 E-value: 4.23e-03
10 20
....*....|....*....|....*...
gi 311641325 559 WTPLHFACHAGQQDIVELLVESGALIDA 586
Cdd:smart00248 3 RTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PHA02989 |
PHA02989 |
ankyrin repeat protein; Provisional |
538-664 |
4.31e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 40.49 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 538 IDVVKFLLEKGANVNATdNFLWTPL-------HFACHAGQQdIVELLVESGALIDAASINNSTPL-----NRAIESCrlD 605
Cdd:PHA02989 50 IKIVKLLIDNGADVNYK-GYIETPLcavlrnrEITSNKIKK-IVKLLLKFGADINLKTFNGVSPIvcfiyNSNINNC--D 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 311641325 606 TVKYLLDIGAkfQLENRKGHSAMDVAKAYADYRII--DLIKEKLDNLPKPAENQKLKGKTP 664
Cdd:PHA02989 126 MLRFLLSKGI--NVNDVKNSRGYNLLHMYLESFSVkkDVIKILLSFGVNLFEKTSLYGLTP 184
|
|
| PHA02989 |
PHA02989 |
ankyrin repeat protein; Provisional |
508-629 |
5.54e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 40.11 E-value: 5.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 508 LKKAFESGIPVDMKDNYYKTPLMTACASGNI---DVVKFLLEKGANVNATDNFL-WTPLH--FACHAGQQDIVELLVESG 581
Cdd:PHA02989 91 VKLLLKFGADINLKTFNGVSPIVCFIYNSNInncDMLRFLLSKGINVNDVKNSRgYNLLHmyLESFSVKKDVIKILLSFG 170
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 311641325 582 A-LIDAASINNSTPLN----RAIESCRLDTVKYLLDIGAKFQLENRKGHSAMD 629
Cdd:PHA02989 171 VnLFEKTSLYGLTPMNiylrNDIDVISIKVIKYLIKKGVNIETNNNGSESVLE 223
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
492-623 |
6.14e-03 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 39.82 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 492 VFSNINIITKAGDLASLkkAFESGIPVDMKDNYYKTPLMTACASG---NIDVVKFLLEKGANVNATDNFLWTPLHFACHA 568
Cdd:PHA02798 78 ILSNIKDYKHMLDIVKI--LIENGADINKKNSDGETPLYCLLSNGyinNLEILLFMIENGADTTLLDKDGFTMLQVYLQS 155
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311641325 569 G---QQDIVELLVESGalIDAASINNSTPLN-------RAIESCRLDTVKYLLDIG---AKFQLENRK 623
Cdd:PHA02798 156 NhhiDIEIIKLLLEKG--VDINTHNNKEKYDtlhcyfkYNIDRIDADILKLFVDNGfiiNKENKSHKK 221
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
529-614 |
6.94e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 39.56 E-value: 6.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 529 LMTACASGNIDVVKFLLEKGAN-VNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTV 607
Cdd:PHA02874 5 LRMCIYSGDIEAIEKIIKNKGNcINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDII 84
|
....*..
gi 311641325 608 KYLLDIG 614
Cdd:PHA02874 85 KLLIDNG 91
|
|
| PHA02741 |
PHA02741 |
hypothetical protein; Provisional |
182-291 |
7.43e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 165108 [Multi-domain] Cd Length: 169 Bit Score: 38.10 E-value: 7.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311641325 182 SSTGRTALMEASREGVVEIVRGILE--RGGEV----NAFDNDRHHAAHFAA----KGGFFDILKLLFAYNGDV-GLISIN 250
Cdd:PHA02741 18 NSEGENFFHEAARCGCFDIIARFTPfiRGDCHaaalNATDDAGQMCIHIAAekheAQLAAEIIDHLIELGADInAQEMLE 97
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 311641325 251 GNTPLHYAAMGGFADCCKYIA-QRGCDLKWKNLDHKTPRAVA 291
Cdd:PHA02741 98 GDTALHLAAHRRDHDLAEWLCcQPGIDLHFCNADNKSPFELA 139
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
37-84 |
8.10e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 35.40 E-value: 8.10e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 311641325 37 PELINYTEPiNGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTP 84
Cdd:pfam13857 6 PIDLNRLDG-EGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTA 52
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
255-296 |
8.11e-03 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 36.25 E-value: 8.11e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 311641325 255 LHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGF 296
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGH 42
|
|
| |
