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titin-cap (telethonin), isoform CRA_a [Homo sapiens]
Telethonin domain-containing protein( domain architecture ID 10559676)
Telethonin domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Telethonin | pfam09470 | Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle ... |
17-167 | 1.98e-72 | |||
Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle protein, titin. The very N-terminus of titin, composed of two immunoglobulin-like (Ig) domains, referred to as Z1 and Z2, interacts with the N-terminal region (residues 1-53) of telethonin, mediating the antiparallel assembly of two Z1Z2 domains. The C-terminus of the telethonin appears to induce dimerization of this 2:1 titin/telethonin structure which thus forms a complex necessary for myofibril assembly and maintenance of the intact Z-disk of skeletal and cardiac muscles. : Pssm-ID: 462811 Cd Length: 150 Bit Score: 214.65 E-value: 1.98e-72
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Name | Accession | Description | Interval | E-value | |||
Telethonin | pfam09470 | Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle ... |
17-167 | 1.98e-72 | |||
Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle protein, titin. The very N-terminus of titin, composed of two immunoglobulin-like (Ig) domains, referred to as Z1 and Z2, interacts with the N-terminal region (residues 1-53) of telethonin, mediating the antiparallel assembly of two Z1Z2 domains. The C-terminus of the telethonin appears to induce dimerization of this 2:1 titin/telethonin structure which thus forms a complex necessary for myofibril assembly and maintenance of the intact Z-disk of skeletal and cardiac muscles. Pssm-ID: 462811 Cd Length: 150 Bit Score: 214.65 E-value: 1.98e-72
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Name | Accession | Description | Interval | E-value | |||
Telethonin | pfam09470 | Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle ... |
17-167 | 1.98e-72 | |||
Telethonin protein; Telethonin is a 167-residue protein which complexes with the large muscle protein, titin. The very N-terminus of titin, composed of two immunoglobulin-like (Ig) domains, referred to as Z1 and Z2, interacts with the N-terminal region (residues 1-53) of telethonin, mediating the antiparallel assembly of two Z1Z2 domains. The C-terminus of the telethonin appears to induce dimerization of this 2:1 titin/telethonin structure which thus forms a complex necessary for myofibril assembly and maintenance of the intact Z-disk of skeletal and cardiac muscles. Pssm-ID: 462811 Cd Length: 150 Bit Score: 214.65 E-value: 1.98e-72
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Blast search parameters | ||||
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