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Conserved domains on  [gi|119605639|gb|EAW85233|]
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family with sequence similarity 86, member A, isoform CRA_e [Homo sapiens]

Protein Classification

protein-lysine N-methyltransferase EEF2KMT family protein( domain architecture ID 11237061)

protein-lysine N-methyltransferase EEF2KMT family protein is a class I SAM-dependent methyltransferase, similar to EEF2KMT that catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM86 pfam14904
Family of unknown function; Function of this protein family is not known.
 6-98 7.73e-55

Family of unknown function; Function of this protein family is not known.


:

Pssm-ID: 464362  Cd Length: 94  Bit Score: 168.68  E-value: 7.73e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119605639    6 NAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVH 85
Cdd:pfam14904   1 SAETERVLREFQRRFLAMRRLRSFPWQSLEEELQNSSSSELLLDILQKTVLHPLCVKFPPSVKYRRCFLSELIKKHEAAG 80

                          90
                  ....*....|...
gi 119605639   86 TEPLDELYEALAE 98
Cdd:pfam14904  81 AEPLDELYEALAE 93
 
Name Accession Description Interval E-value
FAM86 pfam14904
Family of unknown function; Function of this protein family is not known.
 6-98 7.73e-55

Family of unknown function; Function of this protein family is not known.


Pssm-ID: 464362  Cd Length: 94  Bit Score: 168.68  E-value: 7.73e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119605639    6 NAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVH 85
Cdd:pfam14904   1 SAETERVLREFQRRFLAMRRLRSFPWQSLEEELQNSSSSELLLDILQKTVLHPLCVKFPPSVKYRRCFLSELIKKHEAAG 80

                          90
                  ....*....|...
gi 119605639   86 TEPLDELYEALAE 98
Cdd:pfam14904  81 AEPLDELYEALAE 93
 
Name Accession Description Interval E-value
FAM86 pfam14904
Family of unknown function; Function of this protein family is not known.
 6-98 7.73e-55

Family of unknown function; Function of this protein family is not known.


Pssm-ID: 464362  Cd Length: 94  Bit Score: 168.68  E-value: 7.73e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119605639    6 NAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVH 85
Cdd:pfam14904   1 SAETERVLREFQRRFLAMRRLRSFPWQSLEEELQNSSSSELLLDILQKTVLHPLCVKFPPSVKYRRCFLSELIKKHEAAG 80

                          90
                  ....*....|...
gi 119605639   86 TEPLDELYEALAE 98
Cdd:pfam14904  81 AEPLDELYEALAE 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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