|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0303 |
TIGR00906 |
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ... |
585-1187 |
0e+00 |
|
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273330 [Multi-domain] Cd Length: 557 Bit Score: 930.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 585 RAVLTFARCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGL 664
Cdd:TIGR00906 1 RAVLTFARCLIRRKIVDLDSREESKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVARNDSGPAIVLSFLISGLAAVLSGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 665 CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEY 744
Cdd:TIGR00906 81 CYAEFGARVPKAGSAYLYSYVTVGELWAFITGWNLILEYVIGTAAVARSWSAYFDELLNKQIGQFRRTYFKLNYDGLAEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 745 PDFFAVCLILLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEflknisagareppsengtsiY 824
Cdd:TIGR00906 161 PDFFAVCLILLLAVLLSFGVKESAWVNKIFTAINILVLLFVIIAGFTKADVANWSITEE--------------------K 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 825 GAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSP 904
Cdd:TIGR00906 221 GAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPDAP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 905 LPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARV-SKRQSPVAATLTAGVIAAVMAFL 983
Cdd:TIGR00906 301 FPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQInSKTKTPINATVVSGAIAALMAFL 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 984 FDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYIPEKEILESCTSATSKSESqvtmlQGRGFSLRNLFNPsa 1063
Cdd:TIGR00906 381 FDLKALVDLLSIGTLLAYSLVAACVLILRYQPGLVYDQAKDTDEKDTLDSWVPFTSKSES-----QSEGFSLRTLFSG-- 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 1064 lptrqsaslvsflvgflafLILGMSILTTYGVQAIARlEAWSLALLTLFLILCTAVILTIWRQPQNQQKVAFMVPFLPFL 1143
Cdd:TIGR00906 454 -------------------LILGLSILTTYGRAAIAE-EAWSIALLTLFLVLFLLVVLTIWRQPQNKQKVAFKVPLVPFL 513
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 344243823 1144 PAFSILVNIYLMVQLSADTWVRFSIWMGLGFLIYFAYGIRHSLE 1187
Cdd:TIGR00906 514 PALSILINIFLMVQLDADTWVRFAIWMAIGFLIYFLYGIRHSLE 557
|
|
| PotE |
COG0531 |
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism]; |
603-1185 |
2.83e-90 |
|
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain] Cd Length: 438 Bit Score: 298.73 E-value: 2.83e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 603 DSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAkADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLY 682
Cdd:COG0531 2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAA-GLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 683 TYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNkqigqffktyfkmnytglAEYPDFFAVCLILLLAGLLSF 762
Cdd:COG0531 81 ARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFP------------------AGGSVLIALVLILLLTLLNLR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 763 GVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKiseeflknisagareppsengtsiygagGFMPY--GFTGTLAG 840
Cdd:COG0531 143 GVKESAKVNNILTVLKLLVLLLFIVVGLFAFDPANFT----------------------------PFLPAggGLSGVLAA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 841 AATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY-YLLDEKSPLPVAFEYVGWGPAKY 919
Cdd:COG0531 195 LALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYdELAASGAPLADAAEAVFGPWGAI 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 920 VVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATLTAGVIAAVMAFLF--DLKALVDMMSIG 996
Cdd:COG0531 275 LIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRfGTPVNAILLTGVIALLLLLLGaaSFTALASLASVG 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 997 TLMAYSLVAACVLILRyqpglcyeqpkyipekeilesctsatsksesqvtmlqgrgfslrnlfnpsalptrqsaslvsfl 1076
Cdd:COG0531 355 VLLAYLLVALAVIVLR---------------------------------------------------------------- 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 1077 vgflaflilgmsilttygvqaiarleawslalltlflilctaviltiWRQPQNQQkvAFMVPFlPFLPAFSILVNIYLMV 1156
Cdd:COG0531 371 -----------------------------------------------RRRPDLPR--PFRVPL-PLIPILGILLCLFLLY 400
|
570 580
....*....|....*....|....*....
gi 344243823 1157 QLSADTWVRFSIWMGLGFLIYFAYGIRHS 1185
Cdd:COG0531 401 LLGPGALLIGLVLLAIGLLLYLLYRRRHP 429
|
|
| ZnMc_adamalysin_II_like |
cd04269 |
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom ... |
153-340 |
4.41e-63 |
|
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
Pssm-ID: 239797 [Multi-domain] Cd Length: 194 Bit Score: 212.86 E-value: 4.41e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGNLSHVLREILIIVHVINEVYRPLDVEVVLLGVEMWNKKNQVAVTT-IEDLLDGFCYWKTLS 231
Cdd:cd04269 1 KYVELVVVVDNSLYKKYGSNLSKVRQRVIEIVNIVDSIYRPLNIRVVLVGLEIWTDKDKISVSGdAGETLNRFLDWKRSN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 232 LNNRIQNDIAHLFVKHDF-GMYLGLAYVGSVCVPFVNCGVDRLIGRNLVHFGHITAHEMGHNLGMMHDEETCTCGKQACL 310
Cdd:cd04269 81 LLPRKPHDNAQLLTGRDFdGNTVGLAYVGGMCSPKYSGGVVQDHSRNLLLFAVTMAHELGHNLGMEHDDGGCTCGRSTCI 160
|
170 180 190
....*....|....*....|....*....|...
gi 344243823 311 MAPTDNA-SRKFSNCSYASFLR--TYAIAKCLH 340
Cdd:cd04269 161 MAPSPSSlTDAFSNCSYEDYQKflSRGGGQCLL 193
|
|
| ACR |
smart00608 |
ADAM Cysteine-Rich Domain; |
436-572 |
2.01e-60 |
|
ADAM Cysteine-Rich Domain;
Pssm-ID: 214743 Cd Length: 137 Bit Score: 202.98 E-value: 2.01e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 436 LDGSSCKDG-GYCFEKRCNSRDEQCQQIFGKEARSAAQSCYREINTQGDRFGNCGIFRSTYLRCKDSDILCGRVQCENVK 514
Cdd:smart00608 1 QDGTPCDNGqGYCYNGRCPTRDNQCQALFGPGAKVAPDSCYEELNTKGDRFGNCGRENGTYIPCAPEDVKCGKLQCTNVS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 344243823 515 AIPTLEGHSTVHWIHLNGVTCWGTDYHFGMTiPDIGHVKDGTDCGPEHVCIDRKCVNK 572
Cdd:smart00608 81 ELPLLGEHATVIYSNIGGLVCWSLDYHLGTD-PDIGMVKDGTKCGPGKVCINGQCVDV 137
|
|
| ADAM_CR |
pfam08516 |
ADAM cysteine-rich; ADAMs are membrane-anchored proteases that proteolytically modify cell ... |
437-540 |
7.72e-52 |
|
ADAM cysteine-rich; ADAMs are membrane-anchored proteases that proteolytically modify cell surface and extracellular matrix (ECM) in order to alter cell behaviour. It has been shown that the cysteine-rich domain of ADAM13 regulates the protein's metalloprotease activity.
Pssm-ID: 462504 Cd Length: 105 Bit Score: 177.04 E-value: 7.72e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 437 DGSSCKDG-GYCFEKRCNSRDEQCQQIFGKEARSAAQSCYREINTQGDRFGNCGIFRSTYLRCKDSDILCGRVQCENVKA 515
Cdd:pfam08516 1 DGTPCNNGqAYCYNGRCRDRDQQCQELFGKGAKSAPDACYEEVNSKGDRFGNCGRTNGGYVKCEKRDVLCGKLQCTNVKE 80
|
90 100
....*....|....*....|....*
gi 344243823 516 IPTLEGHSTVHWIHLNGVTCWGTDY 540
Cdd:pfam08516 81 LPLLGEHATVIYTNINGVTCWGTDY 105
|
|
| Reprolysin |
pfam01421 |
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that ... |
153-340 |
7.18e-43 |
|
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Members of this family are also known as adamalysins. Most members of this family are snake venom endopeptidases, but there are also some mammalian proteins such as Swiss:P78325, and fertilin. Fertilin and closely related proteins appear to not have some active site residues and may not be active enzymes.
Pssm-ID: 426256 [Multi-domain] Cd Length: 200 Bit Score: 155.15 E-value: 7.18e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGNLSHVLREILIIVHVINEVYRPLDVEVVLLGVEMWNKKNQVAVTT-IEDLLDGFCYWKTLS 231
Cdd:pfam01421 1 KYIELFIVVDKQLFQKMGSDTTVVRQRVFQVVNLVNSIYKELNIRVVLVGLEIWTDEDKIDVSGdANDTLRNFLKWRQEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 232 LNNRIQNDIAHLFVKHDF-GMYLGLAYVGSVCVPFVNCGVDRLIGRNLVHFGHITAHEMGHNLGMMHDEET--CTCGKQA 308
Cdd:pfam01421 81 LKKRKPHDVAQLLSGVEFgGTTVGAAYVGGMCSLEYSGGVNEDHSKNLESFAVTMAHELGHNLGMQHDDFNggCKCPPGG 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 344243823 309 -CLMAPTDNAS--RKFSNCS---YASFLRTYAiAKCLH 340
Cdd:pfam01421 161 gCIMNPSAGSSfpRKFSNCSqedFEQFLTKQK-GACLF 197
|
|
| AA_permease_2 |
pfam13520 |
Amino acid permease; |
614-1026 |
8.25e-41 |
|
Amino acid permease;
Pssm-ID: 404414 [Multi-domain] Cd Length: 427 Bit Score: 156.70 E-value: 8.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 614 LTTMDLIALGVGSTLGAGVYVlAGEVAKAdsGPSIVVSFLIAALASVMAG-LCYAEFGARVPKTGSAYLYTYVTVGELWA 692
Cdd:pfam13520 1 LGLLSAFALVIGSVIGSGIFV-APLVASG--GPALIVWGWIAAIIFSLAVgLVYAELSSALPRSGGIYVYLENAFGKFVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 693 FITGWNLILSYVIGTSSVArawSGTFDELLNkqigQFFKTYFKMNYTGLaeypdFFAVCLILLLAGLLSFGVKESAWVNK 772
Cdd:pfam13520 78 FLAGWSNWFAYVLGLASSA---SVAASYLLS----ALGPDLVPTTWLTY-----GIAIAILIIFAIINIRGVRESAKIQN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 773 FFTAINILVLLFVMV-AGFVKGNvanwkiseeflknisAGAREPPSENGTSiygaggFMPYGFTGTLAGAATCFYAFVGF 851
Cdd:pfam13520 146 ILGILKLLLPLILIIiLGLVTAD---------------GGGFNLLSGEWHT------FFPDGWPGVFAGFLGVLWSFTGF 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 852 DCIATTGEEVRNpqKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLP----VAFEYVGWGPAKYVVAAGSLC 927
Cdd:pfam13520 205 ESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLGqvaaLLFQAVGGKWGAIIVVILLAL 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 928 ALSTSLLGSMFPLPRILFAMARDGLL--FRFLARVSKRQSPVAATLTAGVIAAVMAFLF-----DLKALVDMMSIGTLMA 1000
Cdd:pfam13520 283 SLLGAVNTAIVGASRLLYALARDGVLpfSRFFAKVNKFGSPIRAIILTAILSLILLLLFllspaAYNALLSLSAYGYLLS 362
|
410 420
....*....|....*....|....*.
gi 344243823 1001 YSLVAACVLILRYQPGLCYEQPKYIP 1026
Cdd:pfam13520 363 YLLPIIGLLILRKKRPDLGRIPGRWP 388
|
|
| Disintegrin |
pfam00200 |
Disintegrin; |
360-432 |
1.32e-37 |
|
Disintegrin;
Pssm-ID: 459709 Cd Length: 74 Bit Score: 135.45 E-value: 1.32e-37
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344243823 360 DDGEQCDCGSSEMCTKDSCCR-NDCTFKYGSACAFGLCCKDCKIMPLGTMCREPANECDLPEWCDGHSHECPND 432
Cdd:pfam00200 1 EEGEECDCGSLEECTNDPCCDaKTCKLKPGAQCSSGPCCTNCQFKPAGTVCRPSKDECDLPEYCNGTSAECPPD 74
|
|
| DISIN |
smart00050 |
Homologues of snake disintegrins; Snake disintegrins inhibit the binding of ligands to ... |
360-434 |
6.03e-32 |
|
Homologues of snake disintegrins; Snake disintegrins inhibit the binding of ligands to integrin receptors. They contain a 'RGD' sequence, identical to the recognition site of many adhesion proteins. Molecules containing both disintegrin and metalloprotease domains are known as ADAMs.
Pssm-ID: 214490 Cd Length: 75 Bit Score: 119.33 E-value: 6.03e-32
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 360 DDGEQCDCGSSEMCTkDSCCR-NDCTFKYGSACAFGLCCKDCKIMPLGTMCREPANECDLPEWCDGHSHECPNDVY 434
Cdd:smart00050 1 EEGEECDCGSPKECT-DPCCDpATCKLKPGAQCASGPCCDNCKFKPAGTLCRPSVDECDLPEYCNGTSADCPPDPY 75
|
|
| frlA |
PRK11357 |
amino acid permease; |
620-1015 |
3.21e-23 |
|
amino acid permease;
Pssm-ID: 183096 [Multi-domain] Cd Length: 445 Bit Score: 104.55 E-value: 3.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 620 IALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGW- 697
Cdd:PRK11357 16 LAIAVGTTVGSGIFVSVGEVAKAAGTPWLtVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWa 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 698 NLILSYVIGTSSVARAWSGTFDEL--LNKQIGQFFKTYFKMNYTGLAeypdffaVCLilllagllsfgVKESAWVNKFFT 775
Cdd:PRK11357 96 SFWANDAPSLSIMALAIVSNLGFLtpIDPLLGKFIAAGLIIAFMLLH-------LRS-----------VEGGAAFQTLIT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 776 AINILVLLFVMVAG--FVKGNvanwkiseeflkNISAGAReppsengTSIYGAGGFMpygftGTLAGAATCFYAFVGFDC 853
Cdd:PRK11357 158 IAKIIPFTIVIGLGifWFKAE------------NFAAPTT-------TAIGATGSFM-----ALLAGISATSWSYTGMAS 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 854 IATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY-YLLDEKSPLPVAFEYVG--WGPAKYVVAAGSLCALS 930
Cdd:PRK11357 214 ICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFdKLANSETPISDALTWIPalGSTAGIFVAITAMIVIL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 931 TSLLGSMFPLPRILFAMARDGLLFRFLARVS-KRQSPVAATLTAGVIAAVMAFLFDLKALVDMMSIGTLMAYSLVAACVL 1009
Cdd:PRK11357 294 GSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHpKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSII 373
|
410
....*....|
gi 344243823 1010 ILR----YQP 1015
Cdd:PRK11357 374 WCRkrddYKP 383
|
|
| Pep_M12B_propep |
pfam01562 |
Reprolysin family propeptide; This region is the propeptide for members of peptidase family ... |
7-105 |
2.19e-22 |
|
Reprolysin family propeptide; This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
Pssm-ID: 460254 Cd Length: 128 Bit Score: 93.92 E-value: 2.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 7 LTYSLHFGGQRHVIYMKANKFFMSRHLSVFTYTEQGALHKEQPFVQKDCYYNGYMDGDPESMVALTTClGGFHGMLQINE 86
Cdd:pfam01562 27 LSYRLAAFGKKFHLHLTPNRLLLAPGFTVTYYLDGGTGVESPPVQTDHCYYQGHVEGHPDSSVALSTC-SGLRGFIRTEN 105
|
90 100
....*....|....*....|...
gi 344243823 87 TVYEIKP----KNLSSIFEHLVY 105
Cdd:pfam01562 106 EEYLIEPlekySREEGGHPHVVY 128
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0303 |
TIGR00906 |
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ... |
585-1187 |
0e+00 |
|
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273330 [Multi-domain] Cd Length: 557 Bit Score: 930.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 585 RAVLTFARCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGL 664
Cdd:TIGR00906 1 RAVLTFARCLIRRKIVDLDSREESKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVARNDSGPAIVLSFLISGLAAVLSGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 665 CYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEY 744
Cdd:TIGR00906 81 CYAEFGARVPKAGSAYLYSYVTVGELWAFITGWNLILEYVIGTAAVARSWSAYFDELLNKQIGQFRRTYFKLNYDGLAEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 745 PDFFAVCLILLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEflknisagareppsengtsiY 824
Cdd:TIGR00906 161 PDFFAVCLILLLAVLLSFGVKESAWVNKIFTAINILVLLFVIIAGFTKADVANWSITEE--------------------K 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 825 GAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSP 904
Cdd:TIGR00906 221 GAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPDAP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 905 LPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARV-SKRQSPVAATLTAGVIAAVMAFL 983
Cdd:TIGR00906 301 FPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQInSKTKTPINATVVSGAIAALMAFL 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 984 FDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYIPEKEILESCTSATSKSESqvtmlQGRGFSLRNLFNPsa 1063
Cdd:TIGR00906 381 FDLKALVDLLSIGTLLAYSLVAACVLILRYQPGLVYDQAKDTDEKDTLDSWVPFTSKSES-----QSEGFSLRTLFSG-- 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 1064 lptrqsaslvsflvgflafLILGMSILTTYGVQAIARlEAWSLALLTLFLILCTAVILTIWRQPQNQQKVAFMVPFLPFL 1143
Cdd:TIGR00906 454 -------------------LILGLSILTTYGRAAIAE-EAWSIALLTLFLVLFLLVVLTIWRQPQNKQKVAFKVPLVPFL 513
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 344243823 1144 PAFSILVNIYLMVQLSADTWVRFSIWMGLGFLIYFAYGIRHSLE 1187
Cdd:TIGR00906 514 PALSILINIFLMVQLDADTWVRFAIWMAIGFLIYFLYGIRHSLE 557
|
|
| PotE |
COG0531 |
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism]; |
603-1185 |
2.83e-90 |
|
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain] Cd Length: 438 Bit Score: 298.73 E-value: 2.83e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 603 DSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAkADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLY 682
Cdd:COG0531 2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAA-GLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 683 TYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNkqigqffktyfkmnytglAEYPDFFAVCLILLLAGLLSF 762
Cdd:COG0531 81 ARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFP------------------AGGSVLIALVLILLLTLLNLR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 763 GVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKiseeflknisagareppsengtsiygagGFMPY--GFTGTLAG 840
Cdd:COG0531 143 GVKESAKVNNILTVLKLLVLLLFIVVGLFAFDPANFT----------------------------PFLPAggGLSGVLAA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 841 AATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY-YLLDEKSPLPVAFEYVGWGPAKY 919
Cdd:COG0531 195 LALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYdELAASGAPLADAAEAVFGPWGAI 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 920 VVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATLTAGVIAAVMAFLF--DLKALVDMMSIG 996
Cdd:COG0531 275 LIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRfGTPVNAILLTGVIALLLLLLGaaSFTALASLASVG 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 997 TLMAYSLVAACVLILRyqpglcyeqpkyipekeilesctsatsksesqvtmlqgrgfslrnlfnpsalptrqsaslvsfl 1076
Cdd:COG0531 355 VLLAYLLVALAVIVLR---------------------------------------------------------------- 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 1077 vgflaflilgmsilttygvqaiarleawslalltlflilctaviltiWRQPQNQQkvAFMVPFlPFLPAFSILVNIYLMV 1156
Cdd:COG0531 371 -----------------------------------------------RRRPDLPR--PFRVPL-PLIPILGILLCLFLLY 400
|
570 580
....*....|....*....|....*....
gi 344243823 1157 QLSADTWVRFSIWMGLGFLIYFAYGIRHS 1185
Cdd:COG0531 401 LLGPGALLIGLVLLAIGLLLYLLYRRRHP 429
|
|
| 2A0306 |
TIGR00909 |
amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines] |
610-1012 |
4.86e-73 |
|
amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 129987 [Multi-domain] Cd Length: 429 Bit Score: 250.05 E-value: 4.86e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 610 LCRCLTTMDLIALGVGSTLGAGVYVLAGEVAkADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGE 689
Cdd:TIGR00909 1 LSRELGLFDLTMLGIGAMIGTGIFVVTGIAA-GKAGPAVILSFVLAGLTALFIALVYAELAAMLPVAGSPYTYAYEAMGE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 690 LWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKqIGQFFKTYF--KMNYTGLAEYPDFFAVCLILLLAGLlsfGVKES 767
Cdd:TIGR00909 80 LTAFIIGWSLWLEYGVAVAAVAVGWGGYLQEFLPG-VGLDLPAVLtaKPGNGGVFNLPALLIVLFLTYILYL---GAKES 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 768 AWVNKFFTAINILVLLFVMVAGFVKGNVANWkiseeflknisagarEPpsengtsiygaggFMPYGFTGTLAGAATCFYA 847
Cdd:TIGR00909 156 GKVNDILVVLKVAALLLFAALGAIHFASNNY---------------TP-------------FMPMGFGGVGAATALVFFA 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 848 FVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYY-LLDEKSPLPVAFEYVGWGPAKYVVAAGSL 926
Cdd:TIGR00909 208 FIGFEAISTAAEEVKNPERDIPKAIILSLIVVTLLYVLVAAVILGAVPWRqLAGSTAPLSLVGYDLGQGIGGLILTAGAV 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 927 CALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATLTAGVIAAVMAFLFDLKALVDMMSIGTLMAYSLVA 1005
Cdd:TIGR00909 288 FSIASVMLAGIYGTSRVLFAMSRDGLLPGSLSKVHPKtGTPHMSIIIFSLTAALLASLVPLEGLAELTSIGTLIAFAAVN 367
|
....*..
gi 344243823 1006 ACVLILR 1012
Cdd:TIGR00909 368 VAVIILR 374
|
|
| ZnMc_adamalysin_II_like |
cd04269 |
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom ... |
153-340 |
4.41e-63 |
|
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
Pssm-ID: 239797 [Multi-domain] Cd Length: 194 Bit Score: 212.86 E-value: 4.41e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGNLSHVLREILIIVHVINEVYRPLDVEVVLLGVEMWNKKNQVAVTT-IEDLLDGFCYWKTLS 231
Cdd:cd04269 1 KYVELVVVVDNSLYKKYGSNLSKVRQRVIEIVNIVDSIYRPLNIRVVLVGLEIWTDKDKISVSGdAGETLNRFLDWKRSN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 232 LNNRIQNDIAHLFVKHDF-GMYLGLAYVGSVCVPFVNCGVDRLIGRNLVHFGHITAHEMGHNLGMMHDEETCTCGKQACL 310
Cdd:cd04269 81 LLPRKPHDNAQLLTGRDFdGNTVGLAYVGGMCSPKYSGGVVQDHSRNLLLFAVTMAHELGHNLGMEHDDGGCTCGRSTCI 160
|
170 180 190
....*....|....*....|....*....|...
gi 344243823 311 MAPTDNA-SRKFSNCSYASFLR--TYAIAKCLH 340
Cdd:cd04269 161 MAPSPSSlTDAFSNCSYEDYQKflSRGGGQCLL 193
|
|
| ACR |
smart00608 |
ADAM Cysteine-Rich Domain; |
436-572 |
2.01e-60 |
|
ADAM Cysteine-Rich Domain;
Pssm-ID: 214743 Cd Length: 137 Bit Score: 202.98 E-value: 2.01e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 436 LDGSSCKDG-GYCFEKRCNSRDEQCQQIFGKEARSAAQSCYREINTQGDRFGNCGIFRSTYLRCKDSDILCGRVQCENVK 514
Cdd:smart00608 1 QDGTPCDNGqGYCYNGRCPTRDNQCQALFGPGAKVAPDSCYEELNTKGDRFGNCGRENGTYIPCAPEDVKCGKLQCTNVS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 344243823 515 AIPTLEGHSTVHWIHLNGVTCWGTDYHFGMTiPDIGHVKDGTDCGPEHVCIDRKCVNK 572
Cdd:smart00608 81 ELPLLGEHATVIYSNIGGLVCWSLDYHLGTD-PDIGMVKDGTKCGPGKVCINGQCVDV 137
|
|
| ADAM_CR |
pfam08516 |
ADAM cysteine-rich; ADAMs are membrane-anchored proteases that proteolytically modify cell ... |
437-540 |
7.72e-52 |
|
ADAM cysteine-rich; ADAMs are membrane-anchored proteases that proteolytically modify cell surface and extracellular matrix (ECM) in order to alter cell behaviour. It has been shown that the cysteine-rich domain of ADAM13 regulates the protein's metalloprotease activity.
Pssm-ID: 462504 Cd Length: 105 Bit Score: 177.04 E-value: 7.72e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 437 DGSSCKDG-GYCFEKRCNSRDEQCQQIFGKEARSAAQSCYREINTQGDRFGNCGIFRSTYLRCKDSDILCGRVQCENVKA 515
Cdd:pfam08516 1 DGTPCNNGqAYCYNGRCRDRDQQCQELFGKGAKSAPDACYEEVNSKGDRFGNCGRTNGGYVKCEKRDVLCGKLQCTNVKE 80
|
90 100
....*....|....*....|....*
gi 344243823 516 IPTLEGHSTVHWIHLNGVTCWGTDY 540
Cdd:pfam08516 81 LPLLGEHATVIYTNINGVTCWGTDY 105
|
|
| Reprolysin |
pfam01421 |
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that ... |
153-340 |
7.18e-43 |
|
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Members of this family are also known as adamalysins. Most members of this family are snake venom endopeptidases, but there are also some mammalian proteins such as Swiss:P78325, and fertilin. Fertilin and closely related proteins appear to not have some active site residues and may not be active enzymes.
Pssm-ID: 426256 [Multi-domain] Cd Length: 200 Bit Score: 155.15 E-value: 7.18e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGNLSHVLREILIIVHVINEVYRPLDVEVVLLGVEMWNKKNQVAVTT-IEDLLDGFCYWKTLS 231
Cdd:pfam01421 1 KYIELFIVVDKQLFQKMGSDTTVVRQRVFQVVNLVNSIYKELNIRVVLVGLEIWTDEDKIDVSGdANDTLRNFLKWRQEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 232 LNNRIQNDIAHLFVKHDF-GMYLGLAYVGSVCVPFVNCGVDRLIGRNLVHFGHITAHEMGHNLGMMHDEET--CTCGKQA 308
Cdd:pfam01421 81 LKKRKPHDVAQLLSGVEFgGTTVGAAYVGGMCSLEYSGGVNEDHSKNLESFAVTMAHELGHNLGMQHDDFNggCKCPPGG 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 344243823 309 -CLMAPTDNAS--RKFSNCS---YASFLRTYAiAKCLH 340
Cdd:pfam01421 161 gCIMNPSAGSSfpRKFSNCSqedFEQFLTKQK-GACLF 197
|
|
| AA_permease_2 |
pfam13520 |
Amino acid permease; |
614-1026 |
8.25e-41 |
|
Amino acid permease;
Pssm-ID: 404414 [Multi-domain] Cd Length: 427 Bit Score: 156.70 E-value: 8.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 614 LTTMDLIALGVGSTLGAGVYVlAGEVAKAdsGPSIVVSFLIAALASVMAG-LCYAEFGARVPKTGSAYLYTYVTVGELWA 692
Cdd:pfam13520 1 LGLLSAFALVIGSVIGSGIFV-APLVASG--GPALIVWGWIAAIIFSLAVgLVYAELSSALPRSGGIYVYLENAFGKFVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 693 FITGWNLILSYVIGTSSVArawSGTFDELLNkqigQFFKTYFKMNYTGLaeypdFFAVCLILLLAGLLSFGVKESAWVNK 772
Cdd:pfam13520 78 FLAGWSNWFAYVLGLASSA---SVAASYLLS----ALGPDLVPTTWLTY-----GIAIAILIIFAIINIRGVRESAKIQN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 773 FFTAINILVLLFVMV-AGFVKGNvanwkiseeflknisAGAREPPSENGTSiygaggFMPYGFTGTLAGAATCFYAFVGF 851
Cdd:pfam13520 146 ILGILKLLLPLILIIiLGLVTAD---------------GGGFNLLSGEWHT------FFPDGWPGVFAGFLGVLWSFTGF 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 852 DCIATTGEEVRNpqKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLP----VAFEYVGWGPAKYVVAAGSLC 927
Cdd:pfam13520 205 ESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLGqvaaLLFQAVGGKWGAIIVVILLAL 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 928 ALSTSLLGSMFPLPRILFAMARDGLL--FRFLARVSKRQSPVAATLTAGVIAAVMAFLF-----DLKALVDMMSIGTLMA 1000
Cdd:pfam13520 283 SLLGAVNTAIVGASRLLYALARDGVLpfSRFFAKVNKFGSPIRAIILTAILSLILLLLFllspaAYNALLSLSAYGYLLS 362
|
410 420
....*....|....*....|....*.
gi 344243823 1001 YSLVAACVLILRYQPGLCYEQPKYIP 1026
Cdd:pfam13520 363 YLLPIIGLLILRKKRPDLGRIPGRWP 388
|
|
| Disintegrin |
pfam00200 |
Disintegrin; |
360-432 |
1.32e-37 |
|
Disintegrin;
Pssm-ID: 459709 Cd Length: 74 Bit Score: 135.45 E-value: 1.32e-37
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344243823 360 DDGEQCDCGSSEMCTKDSCCR-NDCTFKYGSACAFGLCCKDCKIMPLGTMCREPANECDLPEWCDGHSHECPND 432
Cdd:pfam00200 1 EEGEECDCGSLEECTNDPCCDaKTCKLKPGAQCSSGPCCTNCQFKPAGTVCRPSKDECDLPEYCNGTSAECPPD 74
|
|
| AA_permease |
pfam00324 |
Amino acid permease; |
618-1012 |
1.28e-33 |
|
Amino acid permease;
Pssm-ID: 366028 [Multi-domain] Cd Length: 467 Bit Score: 136.30 E-value: 1.28e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 618 DLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGW 697
Cdd:pfam00324 1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 698 NLILSYVIGTSSVARAWSGTFdellnkQIGQFFKTYFKMNYTGLAEYPDFFAVCLilllagllsFGVKESA----WVN-- 771
Cdd:pfam00324 81 NYWLSWITVLALELTAASILI------QFWELVPDIPYLWVWGAVFLVLLTIINL---------VGVKWYGeaefWFAli 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 772 KFFTAINILVLLFVMVAGFvkgnvanwkiseeflknisAGAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGF 851
Cdd:pfam00324 146 KIIAIIGFIIVGIILLSGG-------------------NPNDGAIFRYLGDNGGKNNFPPGFGKGFISVFVIAFFAFTGI 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 852 DCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY-------YLLDEKSPLPVAFEYVGWGPAKYVVAAG 924
Cdd:pfam00324 207 ELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpgllnDSASAASPFVIFFKFLGISGLAPLINAV 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 925 SLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAA---TLTAGVIAAVMAFLFDLKA---LVDMMSIGTL 998
Cdd:pfam00324 287 ILTAALSAANSSLYSGSRMLYSLARDGLAPKFLKKVDKRGVPLRAilvSMVISLLALLLASLNPAIVfnfLLAISGLSGL 366
|
410
....*....|....
gi 344243823 999 MAYSLVAACVLILR 1012
Cdd:pfam00324 367 IVWGLISLSHLRFR 380
|
|
| DISIN |
smart00050 |
Homologues of snake disintegrins; Snake disintegrins inhibit the binding of ligands to ... |
360-434 |
6.03e-32 |
|
Homologues of snake disintegrins; Snake disintegrins inhibit the binding of ligands to integrin receptors. They contain a 'RGD' sequence, identical to the recognition site of many adhesion proteins. Molecules containing both disintegrin and metalloprotease domains are known as ADAMs.
Pssm-ID: 214490 Cd Length: 75 Bit Score: 119.33 E-value: 6.03e-32
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 360 DDGEQCDCGSSEMCTkDSCCR-NDCTFKYGSACAFGLCCKDCKIMPLGTMCREPANECDLPEWCDGHSHECPNDVY 434
Cdd:smart00050 1 EEGEECDCGSPKECT-DPCCDpATCKLKPGAQCASGPCCDNCKFKPAGTLCRPSVDECDLPEYCNGTSADCPPDPY 75
|
|
| AnsP |
COG1113 |
L-asparagine transporter or related permease [Amino acid transport and metabolism]; |
606-1012 |
1.44e-30 |
|
L-asparagine transporter or related permease [Amino acid transport and metabolism];
Pssm-ID: 440730 [Multi-domain] Cd Length: 458 Bit Score: 126.77 E-value: 1.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 606 EDSKLCRCLTT--MDLIALGvgSTLGAGVYVLAGEVAKAdSGPSIVVSFLIAALAS--VMAGLcyAEFGARVPKTGSAYL 681
Cdd:COG1113 9 EEEGLKRGLKNrhIQMIALG--GAIGTGLFLGSGKAIAL-AGPAVLLSYLIAGLIVflVMRAL--GEMAVANPVSGSFSD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 682 YTYVTVGELWAFITGWNLILSYVIGTSSVARAwsgtfdellnkqIGQFFKTYFkmnytglaeyPDF----FAVCLILLLA 757
Cdd:COG1113 84 YAREYLGPWAGFVTGWLYWFFWVLVGMAEATA------------VGIYLQFWF----------PDVpqwvWALVFLVLLT 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 758 GLLSFGVK-----ESaWvnkfFTAINIL-VLLFVMVAGFVkgnvanwkiseeflknISAGAREPPSEN-GTS-IYGAGGF 829
Cdd:COG1113 142 AINLLSVKlfgefEF-W----FALIKVVaIVAFIVVGLLL----------------IFFGFGLPGGPPaGLSnLWDHGGF 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 830 MPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPI---GIVTSLLVcFmaYFGVSAALTLMMPYYLLD-EKSPL 905
Cdd:COG1113 201 FPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKainSVIWRILL-F--YVGSLFVILALVPWNQIGaGGSPF 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 906 PVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLT---AGVIAAVMAF 982
Cdd:COG1113 278 VTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAERGDAPKFFGKLSKRGVPVRAILLsavVLLIGVVLNY 357
|
410 420 430
....*....|....*....|....*....|...
gi 344243823 983 LFDLKALVDMMSI---GTLMAYSLVAACVLILR 1012
Cdd:COG1113 358 LLPEKAFTFLLSIsgfGALFVWLMILVSQLKFR 390
|
|
| 2A0308 |
TIGR00911 |
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ... |
601-1014 |
5.88e-29 |
|
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273332 [Multi-domain] Cd Length: 501 Bit Score: 122.55 E-value: 5.88e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 601 TLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYV-------LAGEVakadsGPSIVVsFLIAALASVMAGLCYAEFGARV 673
Cdd:TIGR00911 31 TVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVspkgvlkNAGSV-----GLALIM-WAVCGIFSIVGALVYAELGTTI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 674 PKTGSAYLYTYVTVGELWAFITGWnlILSYVIGTSSVArawsgtfdellnkQIGQFFKTYFKMNYTGLAEYPDF----FA 749
Cdd:TIGR00911 105 PKSGGEYNYILEVFGPLLAFLRLW--IELLVIRPGSQA-------------VNALNFAIYILTPVFPDCEVPEWairlVA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 750 VCLILLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFV---KGNVANWKISEEFlknisagareppSENGTSIYGA 826
Cdd:TIGR00911 170 VLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVqlgKGGVESLNPKNAF------------EGTETSAGGI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 827 GGFMPYGftgtlagaatcFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSL-LVCFMAYFGVSAALTLMMPYYLLdEKSPL 905
Cdd:TIGR00911 238 VLAFYSG-----------IWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMpIVTFIYVLTNIAYFTVLSPEELL-ASLAV 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 906 PVAFEYVGWGPAKYVVAAgsLCALST--SLLGSMFPLPRILFAMARDGLLFRFLARVS-KRQSPVAATLTAGVIAAVMAF 982
Cdd:TIGR00911 306 AVDFGERLLGVMSWAMPA--LVGLSCfgSVNGSLFSSSRLFFVGGREGHLPSLLSMIHvKRLTPLPSLLIVCTLTLLMLF 383
|
410 420 430
....*....|....*....|....*....|..
gi 344243823 983 LFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 1014
Cdd:TIGR00911 384 SGDIYSLINLISFANWLFNALAVAGLLWLRYK 415
|
|
| ZnMc_ADAM_like |
cd04267 |
Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ... |
153-328 |
2.00e-27 |
|
Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ADAM family of metalloproteases contains proteolytic domains from snake venoms, proteases from the mammalian reproductive tract, and the tumor necrosis factor alpha convertase, TACE. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
Pssm-ID: 239795 Cd Length: 192 Bit Score: 110.59 E-value: 2.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGNLSHVLREILIIVHVINEVYRPLD----VEVVLLGVEMWNkkNQVAVTTIE----DLLDGF 224
Cdd:cd04267 1 REIELVVVADHRMVSYFNSDENILQAYITELINIANSIYRSTNlrlgIRISLEGLQILK--GEQFAPPIDsdasNTLNSF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 225 CYWKTlslNNRIQNDIAHLFVKHDF--GMYLGLAYVGSVCVPFVNCGVDRLIGRNLVHfGHITAHEMGHNLGMMHDEETC 302
Cdd:cd04267 79 SFWRA---EGPIRHDNAVLLTAQDFieGDILGLAYVGSMCNPYSSVGVVEDTGFTLLT-ALTMAHELGHNLGAEHDGGDE 154
|
170 180 190
....*....|....*....|....*....|..
gi 344243823 303 TC----GKQACLMAPTDNA--SRKFSNCSYAS 328
Cdd:cd04267 155 LAfecdGGGNYIMAPVDSGlnSYRFSQCSIGS 186
|
|
| AA_permease_C |
pfam13906 |
C-terminus of AA_permease; This is the C-terminus of AA-permease enzymes that is not captured ... |
1135-1185 |
1.27e-25 |
|
C-terminus of AA_permease; This is the C-terminus of AA-permease enzymes that is not captured by the models pfam00324 and pfam13520.
Pssm-ID: 464034 Cd Length: 51 Bit Score: 100.35 E-value: 1.27e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 344243823 1135 FMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMGLGFLIYFAYGIRHS 1185
Cdd:pfam13906 1 FKVPLVPFLPALSILVNIYLMVQLDSLTWIRFGIWMLIGLLIYFGYGIRHS 51
|
|
| ZnMc_ADAMTS_like |
cd04273 |
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) ... |
153-340 |
1.75e-24 |
|
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that combine ADAM-like metalloproteinases with thrombospondin type-1 repeats. ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteinases are inhibited by TIMPs (tissue inhibitors of metalloproteinases), and they play roles in coagulation, angiogenesis, development and progression of arthritis. They hydrolyze the von Willebrand factor precursor and various components of the extracellular matrix.
Pssm-ID: 239801 Cd Length: 207 Bit Score: 102.70 E-value: 1.75e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLNGnlSHVLREILIIVHVINEVYR------PLDVEVVLLgvEMW-NKKNQVAVTT-IEDLLDGF 224
Cdd:cd04273 1 RYVETLVVADSKMVEFHHG--EDLEHYILTLMNIVASLYKdpslgnSINIVVVRL--IVLeDEESGLLISGnAQKSLKSF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 225 CYWKTlSLNNRIQNDIAH-----LFVKHDFGMY------LGLAYVGSVCVPFVNCGVDRLIGRNLvhfGHITAHEMGHNL 293
Cdd:cd04273 77 CRWQK-KLNPPNDSDPEHhdhaiLLTRQDICRSngncdtLGLAPVGGMCSPSRSCSINEDTGLSS---AFTIAHELGHVL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 294 GMMHDEETCTCGKQA---CLMAPT-DNASRKF--SNCS---YASFLRTYaIAKCLH 340
Cdd:cd04273 153 GMPHDGDGNSCGPEGkdgHIMSPTlGANTGPFtwSKCSrryLTSFLDTG-DGNCLL 207
|
|
| frlA |
PRK11357 |
amino acid permease; |
620-1015 |
3.21e-23 |
|
amino acid permease;
Pssm-ID: 183096 [Multi-domain] Cd Length: 445 Bit Score: 104.55 E-value: 3.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 620 IALGVGSTLGAGVYVLAGEVAKADSGPSI-VVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGW- 697
Cdd:PRK11357 16 LAIAVGTTVGSGIFVSVGEVAKAAGTPWLtVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWa 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 698 NLILSYVIGTSSVARAWSGTFDEL--LNKQIGQFFKTYFKMNYTGLAeypdffaVCLilllagllsfgVKESAWVNKFFT 775
Cdd:PRK11357 96 SFWANDAPSLSIMALAIVSNLGFLtpIDPLLGKFIAAGLIIAFMLLH-------LRS-----------VEGGAAFQTLIT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 776 AINILVLLFVMVAG--FVKGNvanwkiseeflkNISAGAReppsengTSIYGAGGFMpygftGTLAGAATCFYAFVGFDC 853
Cdd:PRK11357 158 IAKIIPFTIVIGLGifWFKAE------------NFAAPTT-------TAIGATGSFM-----ALLAGISATSWSYTGMAS 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 854 IATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY-YLLDEKSPLPVAFEYVG--WGPAKYVVAAGSLCALS 930
Cdd:PRK11357 214 ICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFdKLANSETPISDALTWIPalGSTAGIFVAITAMIVIL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 931 TSLLGSMFPLPRILFAMARDGLLFRFLARVS-KRQSPVAATLTAGVIAAVMAFLFDLKALVDMMSIGTLMAYSLVAACVL 1009
Cdd:PRK11357 294 GSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHpKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSII 373
|
410
....*....|
gi 344243823 1010 ILR----YQP 1015
Cdd:PRK11357 374 WCRkrddYKP 383
|
|
| Pep_M12B_propep |
pfam01562 |
Reprolysin family propeptide; This region is the propeptide for members of peptidase family ... |
7-105 |
2.19e-22 |
|
Reprolysin family propeptide; This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
Pssm-ID: 460254 Cd Length: 128 Bit Score: 93.92 E-value: 2.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 7 LTYSLHFGGQRHVIYMKANKFFMSRHLSVFTYTEQGALHKEQPFVQKDCYYNGYMDGDPESMVALTTClGGFHGMLQINE 86
Cdd:pfam01562 27 LSYRLAAFGKKFHLHLTPNRLLLAPGFTVTYYLDGGTGVESPPVQTDHCYYQGHVEGHPDSSVALSTC-SGLRGFIRTEN 105
|
90 100
....*....|....*....|...
gi 344243823 87 TVYEIKP----KNLSSIFEHLVY 105
Cdd:pfam01562 106 EEYLIEPlekySREEGGHPHVVY 128
|
|
| PRK10238 |
PRK10238 |
aromatic amino acid transporter AroP; |
617-1010 |
7.77e-19 |
|
aromatic amino acid transporter AroP;
Pssm-ID: 182324 [Multi-domain] Cd Length: 456 Bit Score: 91.17 E-value: 7.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 617 MDLIALGvgSTLGAGVYVLAGEVAKAdSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITG 696
Cdd:PRK10238 19 IQLIALG--GAIGTGLFLGSASVIQS-AGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 697 WNLILSYVIgtssVARAwsgtfdELlnKQIGQFFKTYFKMNYTgLAEYPDFFAVCLILLLAGLLSFGVKEsAWvnkfFTA 776
Cdd:PRK10238 96 WNYWVLYVL----VAMA------EL--TAVGKYIQFWYPEIPT-WVSAAVFFVVINAINLTNVKVFGEME-FW----FAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 777 INILVLLFVMVAGfvkgnvaNWkiseeFLKNISAGarepPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIAT 856
Cdd:PRK10238 158 IKVIAVVAMIIFG-------GW-----LLFSGNGG----PQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGI 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 857 TGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYY-LLDEKSPLPVAFEYVGwgpAKYVVAAGSLCALSTSLL- 934
Cdd:PRK10238 222 TAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTrVTADTSPFVLIFHELG---DTFVANALNIVVLTAALSv 298
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344243823 935 --GSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFlfdLKALVDMMSIGTLMAysLVAACVLI 1010
Cdd:PRK10238 299 ynSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVL---INYLAPESAFGLLMA--LVVSALVI 371
|
|
| PRK15049 |
PRK15049 |
L-asparagine permease; |
622-1012 |
1.33e-16 |
|
L-asparagine permease;
Pssm-ID: 185009 Cd Length: 499 Bit Score: 84.29 E-value: 1.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 622 LGVGSTLGAGVYVLAGEVAKAdSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLIL 701
Cdd:PRK15049 38 IAIGGAIGTGLFLGAGARLQM-AGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 702 SYvigtssvarAWSGTFDellnkqigqFFKTYFKMNYTG-LAEYPDF-FAVCLILLLAGLLSFGVKESAWVNKFFTAINI 779
Cdd:PRK15049 117 NW---------AMTGIVD---------ITAVALYMHYWGaFGGVPQWvFALAALTIVGTMNMIGVKWFAEMEFWFALIKV 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 780 LVLLFVMVAGFVkgnvanwkiseeFLknisaGAREPPSENGTS---IYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIAT 856
Cdd:PRK15049 179 LAIVTFLVVGTV------------FL-----GSGQPLDGNTTGfhlITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 857 TGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE-KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLG 935
Cdd:PRK15049 242 AAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVMLLPWSAYQAgQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNS 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 936 SMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFLFDL------KALVDMMSIGTLMAYSLVAACVL 1009
Cdd:PRK15049 322 GLYCTGRILRSMAMGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLvpsrvfEIVLNFASLGIIASWAFIIVCQM 401
|
...
gi 344243823 1010 ILR 1012
Cdd:PRK15049 402 RLR 404
|
|
| PRK10249 |
PRK10249 |
phenylalanine transporter; Provisional |
617-1010 |
3.00e-16 |
|
phenylalanine transporter; Provisional
Pssm-ID: 236667 Cd Length: 458 Bit Score: 83.11 E-value: 3.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 617 MDLIALGvgSTLGAGVYVLAGEVAKAdSGPSIVVSFliaALASVMAGLCYAEFGARV---PKTGSAYLYTYVTVGELWAF 693
Cdd:PRK10249 28 IQLIALG--GAIGTGLFLGIGPAIQM-AGPAVLLGY---GVAGIIAFLIMRQLGEMVveePVSGSFAHFAYKYWGPFAGF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 694 ITGWNLILSYV-IGTSSVARAwsgtfdellnkqiGQFFKTYFkmnytglaeyPDffavclilllagllsfgVKESAWVNK 772
Cdd:PRK10249 102 LSGWNYWVMFVlVGMAELTAA-------------GIYMQYWF----------PD-----------------VPTWIWAAA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 773 FFTAINILVLLFVMVAGFVKGNVANWKISEeFLKNISAGAREPPSENGTS------IYGAGGFMPYGFTGTLAGAATCFY 846
Cdd:PRK10249 142 FFIIINAVNLVNVRLYGETEFWFALIKVLA-IIGMIGFGLWLLFSGHGGEkasidnLWRYGGFFATGWNGLILSLAVIMF 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 847 AFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYY-LLDEKSPLPVAFEYVGwgpAKYVVAAGS 925
Cdd:PRK10249 221 SFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVeVKSNSSPFVMIFHNLD---SNVVASALN 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 926 LCALSTSLL---GSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFlfdLKALVDMMSIGTLMAys 1002
Cdd:PRK10249 298 FVILVASLSvynSGVYSNSRMLFGLSVQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVL---INYLLPQKAFGLLMA-- 372
|
....*...
gi 344243823 1003 LVAACVLI 1010
Cdd:PRK10249 373 LVVATLLL 380
|
|
| LysP |
COG0833 |
Amino acid permease [Amino acid transport and metabolism]; |
606-983 |
1.80e-15 |
|
Amino acid permease [Amino acid transport and metabolism];
Pssm-ID: 440595 [Multi-domain] Cd Length: 467 Bit Score: 80.60 E-value: 1.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 606 EDSKLCRCLTT--MDLIALGvgSTLGAGVYVLAGEVAkADSGP-SIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLY 682
Cdd:COG0833 6 KQNKLKRGLKSrhLSMIALG--GVIGTGLFLASGYTI-SQAGPgGALLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQTY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 683 TYVTVGELWAFITGWNLILSYVIGTSS--VARA--------------WSGTFDELLnkqigqffktyFKMNYT-----GL 741
Cdd:COG0833 83 ATRFIDPAFGFAVGWNYWLNWAITVAAelTAAGiimqywfpdvpvwiWSLLFLALI-----------FLLNALsvkafGE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 742 AEYpdFFAVClilllagllsfgvkesawvnKFFTAINILVLLFVMVAGFVKGNVAnwkiseeFLKNISAGareppsengt 821
Cdd:COG0833 152 SEF--WFSLI--------------------KVITVIAFIIVGLLMIFGIIGGHAP-------GFSNFTTG---------- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 822 siygaGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTS---LLVCFMAYFGVSAALtlmMPYYL 898
Cdd:COG0833 193 -----DGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKAIRQVfwrILLFYILAIFVIAAL---IPYTD 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 899 LD-EKSPLPVAFEYVGWGPAKYVVAAGSLCA-LSTSLLGsMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVI 976
Cdd:COG0833 265 AGvAESPFTLVFERAGIPYAADIMNAVILTAvLSAGNSG-LYASTRMLWSLAKEGMAPKIFAKLNKRGVPLNALLATMAV 343
|
....*..
gi 344243823 977 AAvMAFL 983
Cdd:COG0833 344 GL-LALL 349
|
|
| Reprolysin_5 |
pfam13688 |
Metallo-peptidase family M12; |
150-322 |
7.26e-15 |
|
Metallo-peptidase family M12;
Pssm-ID: 372673 Cd Length: 191 Bit Score: 74.38 E-value: 7.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 150 THKRFlDLVLVVDHERIRYLNGNLSHvLREILIIVHVINEVYRPLDVEVVLLGVEMWNKKNQVA-----VTTIEDLLDGF 224
Cdd:pfam13688 1 STRTV-ALLVAADCSYVAAFGGDAAQ-ANIINMVNTASNVYERDFNISLGLVNLTISDSTCPYTppacsTGDSSDRLSEF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 225 CYWKtlSLNNRIQNDIAHLFVKHDFGmYLGLAYVGSVCVPFVNCGVDRLIGRNLVHFG-----HITAHEMGHNLGMMHD- 298
Cdd:pfam13688 79 QDFS--AWRGTQNDDLAYLFLMTNCS-GGGLAWLGQLCNSGSAGSVSTRVSGNNVVVStatewQVFAHEIGHNFGAVHDc 155
|
170 180 190
....*....|....*....|....*....|....*.
gi 344243823 299 -----EETC-----TCGKQA-CLMAPT-DNASRKFS 322
Cdd:pfam13688 156 dsstsSQCCppsnsTCPAGGrYIMNPSsSPNSTDFS 191
|
|
| Reprolysin_3 |
pfam13582 |
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the ... |
183-298 |
1.48e-13 |
|
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the characteriztic binding motif HExxGHxxGxxH of Reprolysin-like peptidases of family M12B.
Pssm-ID: 463926 [Multi-domain] Cd Length: 122 Bit Score: 68.55 E-value: 1.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 183 IVHVINEVY-RPLDVEVVLLGVEMWNKKNQVAVTT-IEDLLDGFCYWKTLSLNNRiQNDIAHLFVKHDFGMYLGLAYVGS 260
Cdd:pfam13582 6 LVNRANTIYeRDLGIRLQLAAIIITTSADTPYTSSdALEILDELQEVNDTRIGQY-GYDLGHLFTGRDGGGGGGIAYVGG 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 344243823 261 VCVpfvncgVDRLIGRNLVH-----FGHIT-AHEMGHNLGMMHD 298
Cdd:pfam13582 85 VCN------SGSKFGVNSGSgpvgdTGADTfAHEIGHNFGLNHT 122
|
|
| proY |
PRK10580 |
putative proline-specific permease; Provisional |
606-1014 |
1.88e-11 |
|
putative proline-specific permease; Provisional
Pssm-ID: 182566 [Multi-domain] Cd Length: 457 Bit Score: 67.92 E-value: 1.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 606 EDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKAdSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYV 685
Cdd:PRK10580 3 SKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKM-AGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 686 TVGELWAFITGWNLILSYVIgtssVARAWSGTFdellnkqiGQFFKTYFkmnytglAEYPDFFAVCLILLLAGLLSF-GV 764
Cdd:PRK10580 82 NLGPLAGYITGWTYCFEILI----VAIADVTAF--------GIYMGVWF-------PTVPHWIWVLSVVLIICAVNLmSV 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 765 KESAWVNKFFTAINILVLLFVMVAGFvkgNVANWKISEeflknisaGAREPPSENgtsIYGAGGFMPYGFTGTLAGAATC 844
Cdd:PRK10580 143 KVFGELEFWFSFFKVATIIIMIVAGI---GIIIWGIGN--------GGQPTGIHN---LWSNGGFFSNGWLGMVMSLQMV 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 845 FYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGvsaALTLMMPYYLLDE----KSPLPVAFEYVGWGPA--- 917
Cdd:PRK10580 209 MFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVG---TLFVIMSIYPWNQvgtnGSPFVLTFQHMGITFAasi 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 918 -KYVVAAGSLCALSTSLLGsmfpLPRILFAMARDGLLFRFLARVSKRQSP---VAATLTAGVIAAVMAFLFDLKALvdmM 993
Cdd:PRK10580 286 lNFVVLTASLSAINSDVFG----VGRMLHGMAEQGSAPKIFSKTSRRGIPwvtVLVMTTALLFAVYLNYIMPENVF---L 358
|
410 420
....*....|....*....|.
gi 344243823 994 SIGTLMAYSLVAACVLILRYQ 1014
Cdd:PRK10580 359 VIASLATFATVWVWIMILLSQ 379
|
|
| ZnMc |
cd00203 |
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
178-333 |
2.04e-11 |
|
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease.
Pssm-ID: 238124 [Multi-domain] Cd Length: 167 Bit Score: 63.70 E-value: 2.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 178 REILIIVHVINEVYRPLD-----VEVVLLGVEMWNKKNQVavttiedlldGFcywkTLSLNNRIQNDIAHLFVKHDFGMY 252
Cdd:cd00203 1 KVIPYVVVADDRDVEEENlsaqiQSLILIAMQIWRDYLNI----------RF----VLVGVEIDKADIAILVTRQDFDGG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 253 -LGLAYVGSVCVPFVNCGVDRLIGRNLVHFGHITAHEMGHNLGMMHDEETCTCGKQA--------------CLMAPTDNA 317
Cdd:cd00203 67 tGGWAYLGRVCDSLRGVGVLQDNQSGTKEGAQTIAHELGHALGFYHDHDRKDRDDYPtiddtlnaedddyySVMSYTKGS 146
|
170 180
....*....|....*....|.
gi 344243823 318 -----SRKFSNCSYASFLRTY 333
Cdd:cd00203 147 fsdgqRKDFSQCDIDQINKLY 167
|
|
| PRK11387 |
PRK11387 |
S-methylmethionine permease; |
606-983 |
4.00e-11 |
|
S-methylmethionine permease;
Pssm-ID: 236904 Cd Length: 471 Bit Score: 66.80 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 606 EDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYV 685
Cdd:PRK11387 8 QAGQFKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVYLVMQCLGELSVAMPETGAFHVYAAR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 686 TVGELWAFITGWNLILSYVIGTSSvarawsgtfdellnkqigQFFKTYFKMNYTgLAEYPDF-----FAVCLILLLAGLL 760
Cdd:PRK11387 88 YLGPATGYTVAWLYWLTWTVALGS------------------SLTAAGFCMQYW-FPQVPVWpwcllFCALIFGLNVVST 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 761 SFGVKESAWVN--KFFTAINILVLLFVMVAGFVKgnvanwkiseeflknISAGAREPPSENGTsiygAGGFMPYGFTGTL 838
Cdd:PRK11387 149 RFFAEGEFWFSliKVVTILAFIVLGGAAIFGFIP---------------MQDGSPAPGLRNLT----AEGWFPHGGLPIL 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 839 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLD-EKSPLPVAFEYVGWGPA 917
Cdd:PRK11387 210 MTMVAVNFAFSGTELIGIAAGETENPAKVIPVAIRTTIARLVIFFVGTVLVLAALIPMQQAGvEKSPFVLVFEKVGIPYA 289
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 918 KYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAAtLTAGVIAAVMAFL 983
Cdd:PRK11387 290 ADIFNFVILTAILSAANSGLYASGRMLWSLSNEGTLPACFARLTKRGIPLTA-LSVSMLGGLLALF 354
|
|
| 2A0304 |
TIGR00907 |
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ... |
646-1016 |
8.67e-11 |
|
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273331 [Multi-domain] Cd Length: 482 Bit Score: 65.92 E-value: 8.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 646 PSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELW----AFITGWNLILSYVIGTSSVAraWSGTFDEL 721
Cdd:TIGR00907 47 MSIVWGWIIAGAGSICIALSLAELSSAYPTSGGQYFWSAKLAPPRQmpfaSWMTGWFNLAGQVAGTASTD--LSVAQLIL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 722 LNKQIGQFFKTYFKMNY--TGLAEYPDFFAvclilllAGLLSFGVKESAWVNKFFTAINILVLLFVMV------------ 787
Cdd:TIGR00907 125 GIVSLTTPGREYIPTRWhiFGIMIGIHLIH-------ALINSLPTKWLPRITSSAAYWSLLGFLTICItllackspkfnd 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 788 AGFVKGNVANwkiseeflknisagareppsengtsiyGAGGFMPYGFT---GTLAGAatcfYAFVGFDCIATTGEEVRNP 864
Cdd:TIGR00907 198 GKFVFTNFNN---------------------------STGGWKPGGFAfllGLLNPA----WSMTGYDGTAHMAEEIENP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 865 QKAIPIGIVTSLLVCFMAYFGVSAALTLMM--PYYLLDEKSPLPVA-FEYVGWGPAKYVVAAGSLCALSTSLLG--SMFP 939
Cdd:TIGR00907 247 EVVGPRAIIGAVAIGIVTGFCFNIVLFFSMgdIDSLISSTTGQPIAqIFYNALGNKAGAIFLLCLILVTSFFCAitCMTA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 940 LPRILFAMARDGLL--FRFLARVSKR-QSPVAATLTAGVIAAVMAFLF-----DLKALVDMMSIGTLMAYSLVAACVLIL 1011
Cdd:TIGR00907 327 NSRMIYAFSRDGGLpfSPLWSRVNPRtQVPLNAVWLSAVWIILIGLLGlgsstAFQAIFSVCTVALDVSYVIPIICKLAK 406
|
....*...
gi 344243823 1012 ---RYQPG 1016
Cdd:TIGR00907 407 grnTIAPG 414
|
|
| PRK10836 |
PRK10836 |
lysine transporter; Provisional |
603-983 |
2.54e-09 |
|
lysine transporter; Provisional
Pssm-ID: 182767 Cd Length: 489 Bit Score: 61.37 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 603 DSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAG-EVAKADSGPSIVVSFLIAALAS-VMAGLcyAEFGARVPKTGSAY 680
Cdd:PRK10836 6 KTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGaTISQAGPGGALLSYMLIGLMVYfLMTSL--GELAAYMPVSGSFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 681 LYTYVTVGELWAFITGWNLILSY--VIGTSSVArawsgtfdellnkqiGQFFKTYFKMNYTGLAEYPDFFAVCLILLLAG 758
Cdd:PRK10836 84 TYGQNYVEEGFGFALGWNYWYNWavTIAVDLVA---------------AQLVMSWWFPDTPGWIWSALFLGVIFLLNYIS 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 759 LLSFGVKESaWVN--KFFTAINILVLLFVMVAGFVKGNVA----NWKIseeflknisagareppsengtsiygagGFMPY 832
Cdd:PRK10836 149 VRGFGEAEY-WFSliKVTTVIVFIIVGVLMIIGIFKGAEPagwsNWTI---------------------------GDAPF 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 833 --GFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPY---YLL--DEK--- 902
Cdd:PRK10836 201 agGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYtdpSLLrnDVKdis 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 903 -SPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAAtLTAGVIAAVMA 981
Cdd:PRK10836 281 vSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPRIFAKLSRGGVPRNA-LYATTVIAGLC 359
|
..
gi 344243823 982 FL 983
Cdd:PRK10836 360 FL 361
|
|
| PRK11021 |
PRK11021 |
putative transporter; Provisional |
834-984 |
2.69e-08 |
|
putative transporter; Provisional
Pssm-ID: 236823 [Multi-domain] Cd Length: 410 Bit Score: 57.61 E-value: 2.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 834 FTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALtLMMPYYLLDEKS--PLPVAFEY 911
Cdd:PRK11021 176 WSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGLVYWACTVVV-LHFPAYGDKQAAaaSLPGIFVQ 254
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 912 VGWGPAKYVVAA-GSLCALSTS--LLGSmfpLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFLF 984
Cdd:PRK11021 255 LFGGYALWVICViGYLACFASVniYTQS---FARLVWSQAREGRPPSYLARLSARGVPVNALNAVLGCCAVSILLI 327
|
|
| PRK11049 |
PRK11049 |
D-alanine/D-serine/glycine permease; Provisional |
821-966 |
3.43e-08 |
|
D-alanine/D-serine/glycine permease; Provisional
Pssm-ID: 236830 Cd Length: 469 Bit Score: 57.44 E-value: 3.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 821 TSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQK-------AIPIGIVTsllvcfmayFGVSAALTLM 893
Cdd:PRK11049 197 AHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKslprainSIPIRIIM---------FYVFALIVIM 267
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344243823 894 --MPYY-LLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSP 966
Cdd:PRK11049 268 svTPWSsVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKLSKRAVP 343
|
|
| 2A0310 |
TIGR00913 |
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines] |
619-977 |
4.00e-08 |
|
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273334 Cd Length: 478 Bit Score: 57.29 E-value: 4.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 619 LIALGvgSTLGAGVYVLAGEvAKADSGP-SIVVSFLIAA--LASVMAGLcyAEFGARVPKTGSAYlYTYVT--VGELWAF 693
Cdd:TIGR00913 11 MIALG--GTIGTGLLVGSGT-ALATGGPaGLLIGYAIMGsiIYCVMQSL--GEMATFYPVVSGSF-ATYASrfVDPAFGF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 694 ITGWNLILSYVIGTSSVARAWSGTfdellnkqigqffktyfkMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESA----W 769
Cdd:TIGR00913 85 AVGWNYWLQWLIVLPLELVTASMT------------------IQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGeaefW 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 770 VN--KFFTAINILVLLFVMVAGfvkGNVANWKISEEFLKNisAGAREPPSENGTsiygaggfmpygFTGTLAGAATCFYA 847
Cdd:TIGR00913 147 FSsiKILAIIGFIILSIILNCG---GGPNHGYIGFRYWHD--PGAFAGGTIGGR------------FKGVCSVFVTAAFS 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 848 FVGFDCIATTGEEVRNPQKAIP------------IGIVTSLLVCFMAYFG---VSAALTLMMPYylldeKSPLPVAFEYV 912
Cdd:TIGR00913 210 FGGTELVALTAGEAANPRKSIPraakrtfwrilvFYILTLFLIGFLVPYNdprLLSSSSSSDSA-----ASPFVIAIQNH 284
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344243823 913 GWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSP---VAATLTAGVIA 977
Cdd:TIGR00913 285 GIKVLPHIFNAVILISVLSAANSSLYASSRTLYALAHQGLAPKIFAYVDRRGVPyvaVIVSSLFGLLA 352
|
|
| Reprolysin_2 |
pfam13574 |
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the ... |
176-347 |
4.49e-08 |
|
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the characteriztic binding motif HExxGHxxGxxH of Reprolysin-like peptidases of family M12B.
Pssm-ID: 372637 Cd Length: 193 Bit Score: 54.56 E-value: 4.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 176 VLREILIIVHVINEVYRPLDVEVvllGVEMWNKKNQVAVTTIEDLLDGFCYWKTLSLNNRI---------QNDIAHLFVK 246
Cdd:pfam13574 3 VTENLVNVVNRVNQIYEPDDINI---NGGLVNPGEIPATTSASDSGNNYCNSPTTIVRRLNflsqwrgeqDYCLAHLVTM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 247 HDF-GMYLGLAYVGSVCV-----PFVNCGVDRLI--GRNLVHFGHI--TAHEMGHNLGMMHDeetCTCGKQACLMAPTDN 316
Cdd:pfam13574 80 GTFsGGELGLAYVGQICQkgassPKTNTGLSTTTnyGSFNYPTQEWdvVAHEVGHNFGATHD---CDGSQYASSGCERNA 156
|
170 180 190
....*....|....*....|....*....|.
gi 344243823 317 ASRKFSNCSYasFLRTYAiAKCLHKEKKPVS 347
Cdd:pfam13574 157 ATSVCSANGS--FIMNPA-SKSNNDLFSPCS 184
|
|
| PRK10197 |
PRK10197 |
GABA permease; |
622-1012 |
3.16e-07 |
|
GABA permease;
Pssm-ID: 182297 Cd Length: 446 Bit Score: 54.24 E-value: 3.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 622 LGVGSTLGAGVYVlAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLIL 701
Cdd:PRK10197 2 LSIAGVIGASLFV-GSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 702 SYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTG--------LAEYPDFFAVClilllagllsfgvkesawvnKF 773
Cdd:PRK10197 81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGsnllsvknYGEFEFWLALC--------------------KV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 774 FTAINILVLLFVMVAGFVKgnvanwkiseefLKNISAGAReppsengtsIYGAGGFMPYGFTGTLAGAATCFYAFVGFDC 853
Cdd:PRK10197 141 IAILAFIFLGAVAISGFYP------------YAEVSGISR---------LWDSGGFMPNGFGAVLSAMLITMFSFMGAEI 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 854 IATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL--LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALST 931
Cdd:PRK10197 200 VTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMpgLKAVGSYRSVLELLNIPHAKLIMDCVILLSVTS 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 932 SLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSP-VAATLTAG-----VIAAVMAFLFDLKALVDMMSIGTLMAYSLVA 1005
Cdd:PRK10197 280 CLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPyVAVLLSTGaafltVVVNYYAPAKVFKFLIDSSGAIALLVYLVIA 359
|
....*..
gi 344243823 1006 ACVLILR 1012
Cdd:PRK10197 360 VSQLRMR 366
|
|
| Reprolysin_4 |
pfam13583 |
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the ... |
153-325 |
3.33e-07 |
|
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the characteriztic binding motif HExxGHxxGxxH of Reprolysin-like peptidases of family M12B.
Pssm-ID: 404471 Cd Length: 203 Bit Score: 52.24 E-value: 3.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 153 RFLDLVLVVDHERIRYLnGNLSHVLREILIIVHVINEVY-RPLDVEVVLLGVEMWNKKN-QVAVTTIEDLLDGFCYWKTL 230
Cdd:pfam13583 3 RVYRVAVATDCTYSASF-GSVDELRANINATVTTANEVYgRDFNVSLALISDRDVIYTDsSTDSFNADCSGGDLGNWRLA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 231 SLNNRI---QNDIAHLFvkHDFGMY---LGLAYVGSVCVPFVN---CGVDRLIGRNLvhfgHITAHEMGHNLGMMHDEET 301
Cdd:pfam13583 82 TLTSWRdslNYDLAYLT--LMTGPSgqnVGVAWVGALCSSARQnakASGVARSRDEW----DIFAHEIGHTFGAVHDCSS 155
|
170 180 190
....*....|....*....|....*....|...
gi 344243823 302 CTCG--KQAC------LMAPTDNASRK-FSNCS 325
Cdd:pfam13583 156 QGEGlsSSTEdgsgqtIMSYASTASQTaFSPCT 188
|
|
| ZnMc_TACE_like |
cd04270 |
Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha ... |
157-332 |
3.60e-07 |
|
Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
Pssm-ID: 239798 [Multi-domain] Cd Length: 244 Bit Score: 52.76 E-value: 3.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 157 LVLVVDHERIRYL-NGNLSHVLREILIIVHVINEVYRPLDVEVVL---LGVEMwnkkNQVAVTTIEDLLDG------FCY 226
Cdd:cd04270 5 LLLVADHRFYKYMgRGEEETTINYLISHIDRVDDIYRNTDWDGGGfkgIGFQI----KRIRIHTTPDEVDPgnkfynKSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 227 --W---KTLSLNNRIQND----IAHLFVKHDFGM-YLGLAYVGS--------VCVP--FVNCGVDRLIGRNLV----HFG 282
Cdd:cd04270 81 pnWgveKFLVKLLLEQFSddvcLAHLFTYRDFDMgTLGLAYVGSprdnsaggICEKayYYSNGKKKYLNTGLTttvnYGK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344243823 283 HI--------TAHEMGHNLGMMHD--EETCTCGKQA---CLMAPT-----DNASRKFSNCSYASFLRT 332
Cdd:cd04270 161 RVptkesdlvTAHELGHNFGSPHDpdIAECAPGESQggnYIMYARatsgdKENNKKFSPCSKKSISKV 228
|
|
| PRK10644 |
PRK10644 |
arginine/agmatine antiporter; |
625-1013 |
7.64e-07 |
|
arginine/agmatine antiporter;
Pssm-ID: 182613 [Multi-domain] Cd Length: 445 Bit Score: 53.26 E-value: 7.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 625 GSTLGAGVYVLAGEVAKadSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITgwNLI--LS 702
Cdd:PRK10644 21 GNIMGSGVFLLPANLAS--TGGIAIYGWLVTIIGALGLSMVYAKMSSLDPSPGGSYAYARRCFGPFLGYQT--NVLywLA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 703 YVIGTSSVARAWSGTFdellnkqigqffkTYFkmnYTGLAEyPDFFAVCLIL---LLAGLLSFGVKESAWVNKFFTAINI 779
Cdd:PRK10644 97 CWIGNIAMVVIGVGYL-------------SYF---FPILKD-PLVLTITCVVvlwIFVLLNIVGPKMITRVQAVATVLAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 780 LVLLFVMVAG--FVKGNV--ANWKISeeflknisagareppsenGTSIYGAGGfmpygftgtlAGAATCFYAFVGFDCIA 855
Cdd:PRK10644 160 IPIVGIAVFGwfWFRGETymAAWNVS------------------GLGTFGAIQ----------STLNVTLWSFIGVESAS 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 856 TTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMP-YYLLDEKSPLPVAFEYVGWGPAKYVVaagSLCALS---T 931
Cdd:PRK10644 212 VAAGVVKNPKRNVPIATIGGVLIAAVCYVLSSTAIMGMIPnAALRVSASPFGDAARMALGDTAGAIV---SFCAAAgclG 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 932 SLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFL---------FDLKALVDMmsIGTLMAYS 1002
Cdd:PRK10644 289 SLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLLIVGVLMTIFQLSsispnaskeFGLVSSVSV--IFTLVPYL 366
|
410
....*....|.
gi 344243823 1003 LVAACVLILRY 1013
Cdd:PRK10644 367 YTCAALLLLGH 377
|
|
| 2a30 |
TIGR00930 |
K-Cl cotransporter; [Transport and binding proteins, Other] |
763-1004 |
1.82e-05 |
|
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain] Cd Length: 953 Bit Score: 49.33 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 763 GVKesaWVNKFftAINILVLLFVMVAGFVKGNV--ANWKI--------SEEFLKNISAGAREPPSeNGTSIYGAggFMPy 832
Cdd:TIGR00930 221 GME---WENKA--QVLFLVIVLLSILNIFVGTIipAFDKPakgffglgNEIFSENFIPGIPGPEG-GFFSLFGI--FFP- 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 833 GFTGTLAGAatcfyafvgfdciaTTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSA-----------------ALTLMMP 895
Cdd:TIGR00930 292 SVTGILAGA--------------NISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVlfgacvvrdatgdkndtLVTNCTS 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 896 YYLLDEKSPLPVAFEYV----------GWGPakyVVAAGSLCALSTSLLGSMFPLPRILFAMARDGL--LFRFLAR-VSK 962
Cdd:TIGR00930 358 AACFSECAHNTCSYGLMnnlqvmslvsPFPP---LITAGIFSATLSSALASLVSAPRLFQALCKDNIypFLQFFGKgYGK 434
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 344243823 963 RQSPVAATLTAGVIAAVMAFLFDLKALVDMMSIGTLMAYSLV 1004
Cdd:TIGR00930 435 NGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALI 476
|
|
| potE |
PRK10655 |
putrescine transporter; Provisional |
846-1016 |
2.93e-05 |
|
putrescine transporter; Provisional
Pssm-ID: 182622 Cd Length: 438 Bit Score: 48.10 E-value: 2.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 846 YAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYY-LLDEKSPLPVAFEYVGWGPAKYVVAAG 924
Cdd:PRK10655 200 WAFLGLESACANSDAVENPERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMeLANSTAPFGLAFAQMFNPTVGKIVMAL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 925 SLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVIAAVMAFLF-------DLKALVDMMSIGT 997
Cdd:PRK10655 280 MVMSCCGSLLGWQFTIAQVFKSSADEGYFPKIFSRVTKVDAPVQGMLIIVVIQSLLSLMTispslnsQFNVLVNLAVVTN 359
|
170
....*....|....*....
gi 344243823 998 LMAYSLVAACVLILRYQPG 1016
Cdd:PRK10655 360 IIPYILSMAALVIIQKVAN 378
|
|
| ZnMc_salivary_gland_MPs |
cd04272 |
Zinc-dependent metalloprotease, salivary_gland_MPs. Metalloproteases secreted by the salivary ... |
253-340 |
3.80e-05 |
|
Zinc-dependent metalloprotease, salivary_gland_MPs. Metalloproteases secreted by the salivary glands of arthropods.
Pssm-ID: 239800 Cd Length: 220 Bit Score: 46.19 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 253 LGLAYVGSVCVP-FVNCGVDRligrnlVHF--GHIT-AHEMGHNLGMMHDEETCT------CGKQAC------LMAPTDN 316
Cdd:cd04272 119 GGYAYVGGACTEnRVAMGEDT------PGSyyGVYTmTHELAHLLGAPHDGSPPPswvkghPGSLDCpwddgyIMSYVVN 192
|
90 100
....*....|....*....|....*....
gi 344243823 317 ASR--KFSNCSYAS---FLRTYAiAKCLH 340
Cdd:cd04272 193 GERqyRFSQCSQRQirnVFRRLG-ASCLH 220
|
|
| ZnMc_ADAM_fungal |
cd04271 |
Zinc-dependent metalloprotease, ADAM_fungal subgroup. The adamalysin_like or ADAM (A ... |
215-325 |
1.12e-03 |
|
Zinc-dependent metalloprotease, ADAM_fungal subgroup. The adamalysin_like or ADAM (A Disintegrin And Metalloprotease) family of metalloproteases are integral membrane proteases acting on a variety of extracellular targets. They are involved in shedding soluble peptides or proteins from the cell surface. This subfamily contains fungal ADAMs, whose precise function has yet to be determined.
Pssm-ID: 239799 [Multi-domain] Cd Length: 228 Bit Score: 42.02 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344243823 215 TTIEDLLDGFCYWKtlslNNRIQNDIA--HLFVKHDFGMYLGLAYVGSVCVPfvncgvDRLIGRNLVHFG---------- 282
Cdd:cd04271 76 IDIDDRLSIFSQWR----GQQPDDGNAfwTLMTACPSGSEVGVAWLGQLCRT------GASDQGNETVAGtnvvvrtsne 145
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344243823 283 -HITAHEMGHNLGMMHDEETCTC-----GKQAC--------------LMAP-TDNASRKFSNCS 325
Cdd:cd04271 146 wQVFAHEIGHTFGAVHDCTSGTCsdgsvGSQQCcplststcdangqyIMNPsSSSGITEFSPCT 209
|
|
| |
