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Conserved domains on  [gi|575003694|gb|ETW64103|]
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hypothetical protein PFMC_00127 [Plasmodium falciparum CAMP/Malaysia]

Protein Classification

DnaJ and DnaJ-X domain-containing protein( domain architecture ID 10446315)

DnaJ and DnaJ-X domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ-X super family cl14778
X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a ...
 420-701 2.30e-159

X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a three-domain structure. The x-domain lies between the N-terminal DnaJ and the C-terminal Z domains. The exact function is not known.


The actual alignment was detected with superfamily member PTZ00475:

Pssm-ID: 449354  Cd Length: 282  Bit Score: 461.03  E-value: 2.30e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 420 MIIIDPLIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEKVAELLKDRLDLYID 499
Cdd:PTZ00475   1 MIIIVPFIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEEVAELLKDRLDLYID 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 500 NEDEWKKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEEKANSGKNKKDIYLKEANERMIRNSIVLRQCKSRFISI 579
Cdd:PTZ00475  81 NEDEWEKLMENEISMLLKSSFSNFILESIGWTYENVSNIFLEEKANSGINKKDIYLKEANERMIRNSIVLRQCKSRFISI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 580 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 659
Cdd:PTZ00475 161 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 575003694 660 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 701
Cdd:PTZ00475 241 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 282
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 347-410 3.36e-15

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 70.19  E-value: 3.36e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 575003694  347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVmNQKFENISEAYQILGYENRRKLYD 410
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEA-EEKFKEINEAYEVLSDPEKRAIYD 63
 
Name Accession Description Interval E-value
PTZ00475 PTZ00475
RESA-like protein; Provisional
 420-701 2.30e-159

RESA-like protein; Provisional


Pssm-ID: 185654  Cd Length: 282  Bit Score: 461.03  E-value: 2.30e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 420 MIIIDPLIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEKVAELLKDRLDLYID 499
Cdd:PTZ00475   1 MIIIVPFIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEEVAELLKDRLDLYID 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 500 NEDEWKKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEEKANSGKNKKDIYLKEANERMIRNSIVLRQCKSRFISI 579
Cdd:PTZ00475  81 NEDEWEKLMENEISMLLKSSFSNFILESIGWTYENVSNIFLEEKANSGINKKDIYLKEANERMIRNSIVLRQCKSRFISI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 580 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 659
Cdd:PTZ00475 161 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 575003694 660 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 701
Cdd:PTZ00475 241 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 282
DnaJ-X pfam14308
X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a ...
 479-700 1.09e-16

X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a three-domain structure. The x-domain lies between the N-terminal DnaJ and the C-terminal Z domains. The exact function is not known.


Pssm-ID: 433858  Cd Length: 205  Bit Score: 79.11  E-value: 1.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  479 QNIREEKVAELLKDRLDLYI------DNEDEWKKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEekansgknkkd 552
Cdd:pfam14308   1 QKEREEELAEKLRDRLSPYVeadkpgDVLDEFEEKLEEEAEDLKLESFGVEILHTIGWVYENKAKSFLK----------- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  553 iylkeanermirnsivlrqcKSRFISIITNYYPFKEQNNpFIKQAQYVSSSNYvldDIINnidySIDNIHRAIDNLYYEH 632
Cdd:pfam14308  70 --------------------SQKFLGVGGFFSSVKEKGR-TVKNTWNTLSSAL---DAQS----TMEEMAKEEEKGGEEL 121

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 575003694  633 ILNLLEEEKNEILEEILRNILKIILCDVETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKmILQKV 700
Cdd:pfam14308 122 TEEELAKLEELLTGKILAAAWAGSKFEIESTLREVCDKVLKDKSVPKKTRIKRAEALLILGK-IFQKA 188
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 347-410 3.36e-15

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 70.19  E-value: 3.36e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 575003694  347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVmNQKFENISEAYQILGYENRRKLYD 410
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEA-EEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
346-405 1.01e-12

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 63.41  E-value: 1.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694   346 RSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVMNQKFENISEAYQILGYENR 405
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 344-410 1.47e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 69.80  E-value: 1.47e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPE--AEEKFKEINEAYQVLSDPEKRKLYD 65
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 347-410 8.53e-12

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 67.24  E-value: 8.53e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 575003694  347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKE--AEEKFKEINEAYEVLSDPEKRAQYD 62
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 348-401 2.37e-11

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 59.10  E-value: 2.37e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 575003694 348 YYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILG 401
Cdd:cd06257    2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPD-DPEAEEKFKEINEAYEVLS 54
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 347-418 5.74e-11

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 60.87  E-value: 5.74e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 575003694 347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYDLGEYDETN 418
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPG-DPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAEL 71
 
Name Accession Description Interval E-value
PTZ00475 PTZ00475
RESA-like protein; Provisional
 420-701 2.30e-159

RESA-like protein; Provisional


Pssm-ID: 185654  Cd Length: 282  Bit Score: 461.03  E-value: 2.30e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 420 MIIIDPLIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEKVAELLKDRLDLYID 499
Cdd:PTZ00475   1 MIIIVPFIFFNLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEEVAELLKDRLDLYID 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 500 NEDEWKKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEEKANSGKNKKDIYLKEANERMIRNSIVLRQCKSRFISI 579
Cdd:PTZ00475  81 NEDEWEKLMENEISMLLKSSFSNFILESIGWTYENVSNIFLEEKANSGINKKDIYLKEANERMIRNSIVLRQCKSRFISI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 580 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 659
Cdd:PTZ00475 161 ITNYYPFKEQNNPFIKQAQYVSSSNYVLDDIINNIDYSIDNIHRAIDNLYYEHILNLLEEEKNEILEEILRNILKIILCD 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 575003694 660 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 701
Cdd:PTZ00475 241 VETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKMILQKVN 282
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 348-696 3.39e-31

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 131.06  E-value: 3.39e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  348 YYDILDVKEDSDINEIKRKFYNLSLKYYPKmNKDKNLVMnQKFENISEAYQILGYENRRKLYDLGEYDETNKMIIIDPLI 427
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPP-KRSGNEGF-HKFKKINEAYQILGDIDKKKMYNKFGYDGIKGVNFIHPSI 652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  428 FFnLIFTSDMMYEYIENTKVPIFVKLFFGKSIFIEDIFYYVGMIMKEMMEGQNIREEKVAELLKDRLDLYIDNEDEWKKL 507
Cdd:PTZ00341  653 FY-LLASLEKFADFTGSPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKEREAHISENLINILQPCIAGDRKWDVP 731

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  508 MENEISMLLKSSFSSFILESIGWTYENVSnifleeKANSGKNKKDIylKEANERMIRNSIVLRQCKSRFISIITNYYPFK 587
Cdd:PTZ00341  732 IIDKIEELKGSPFDIAIIDSIGWIFKHVA------KSHLKKPKKAA--KKLEQRSKANKEELANENNKLMNILKEYFGNN 803

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  588 EQnnpfikqaqyvsssnyvlddiINNIDYSIDNIHRAIDNLY-YEHILNLLEEEKNEILEEILRNILKIILCDVETTVRR 666
Cdd:PTZ00341  804 EQ---------------------INSITYNFENINLNEDNENgSKKILDLNHKDQKEIFEEIISYIVDISLSDIENTAKN 862

                         330       340       350
                  ....*....|....*....|....*....|
gi 575003694  667 SAQKVLQNAEGDTNLMLKRAKGLQSLGKMI 696
Cdd:PTZ00341  863 AAEQILSDEGLDEKKLKKRAESLKKLANAI 892
DnaJ-X pfam14308
X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a ...
 479-700 1.09e-16

X-domain of DnaJ-containing; IN certain plant and yeast proteins, the DnaJ-1 proteins have a three-domain structure. The x-domain lies between the N-terminal DnaJ and the C-terminal Z domains. The exact function is not known.


Pssm-ID: 433858  Cd Length: 205  Bit Score: 79.11  E-value: 1.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  479 QNIREEKVAELLKDRLDLYI------DNEDEWKKLMENEISMLLKSSFSSFILESIGWTYENVSNIFLEekansgknkkd 552
Cdd:pfam14308   1 QKEREEELAEKLRDRLSPYVeadkpgDVLDEFEEKLEEEAEDLKLESFGVEILHTIGWVYENKAKSFLK----------- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694  553 iylkeanermirnsivlrqcKSRFISIITNYYPFKEQNNpFIKQAQYVSSSNYvldDIINnidySIDNIHRAIDNLYYEH 632
Cdd:pfam14308  70 --------------------SQKFLGVGGFFSSVKEKGR-TVKNTWNTLSSAL---DAQS----TMEEMAKEEEKGGEEL 121

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 575003694  633 ILNLLEEEKNEILEEILRNILKIILCDVETTVRRSAQKVLQNAEGDTNLMLKRAKGLQSLGKmILQKV 700
Cdd:pfam14308 122 TEEELAKLEELLTGKILAAAWAGSKFEIESTLREVCDKVLKDKSVPKKTRIKRAEALLILGK-IFQKA 188
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 347-410 3.36e-15

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 70.19  E-value: 3.36e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 575003694  347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVmNQKFENISEAYQILGYENRRKLYD 410
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEA-EEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
346-405 1.01e-12

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 63.41  E-value: 1.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694   346 RSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVMNQKFENISEAYQILGYENR 405
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 344-410 1.47e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 69.80  E-value: 1.47e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPE--AEEKFKEINEAYQVLSDPEKRKLYD 65
PRK14280 PRK14280
molecular chaperone DnaJ;
345-410 5.28e-12

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 68.21  E-value: 5.28e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14280   3 KRDYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEEG--ADEKFKEISEAYEVLSDDQKRAQYD 66
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 345-410 8.02e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 67.57  E-value: 8.02e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14298   4 TRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKEPD--AEEKFKEISEAYAVLSDAEKRAQYD 67
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 347-410 8.53e-12

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 67.24  E-value: 8.53e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 575003694  347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKE--AEEKFKEINEAYEVLSDPEKRAQYD 62
PRK14295 PRK14295
molecular chaperone DnaJ;
339-410 2.20e-11

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 66.41  E-value: 2.20e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 575003694 339 NTRNNMKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14295   2 STKDYIEKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKG-DAKAEERFKEISEAYDVLSDEKKRKEYD 72
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 348-401 2.37e-11

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 59.10  E-value: 2.37e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 575003694 348 YYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILG 401
Cdd:cd06257    2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPD-DPEAEEKFKEINEAYEVLS 54
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 347-418 5.74e-11

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 60.87  E-value: 5.74e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 575003694 347 SYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYDLGEYDETN 418
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPG-DPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAEL 71
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 344-410 5.76e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 64.83  E-value: 5.76e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14281   1 MKRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPD-NKEAEEHFKEVNEAYEVLSNDDKRRRYD 66
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 345-410 2.40e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 62.92  E-value: 2.40e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14283   4 KRDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEEEG--AEEKFKEISEAYAVLSDDEKRQRYD 67
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 344-410 3.48e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 62.51  E-value: 3.48e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14277   3 AKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPG-DKEAEQKFKEINEAYEILSDPQKRAQYD 68
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 345-410 4.44e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 62.03  E-value: 4.44e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14276   3 NTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKEPG--AEEKYKEVQEAYETLSDPQKRAAYD 66
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 344-410 1.11e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 60.93  E-value: 1.11e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNK-DKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPgDKE--AEEKFKEIKEAYEVLSDPQKRAAYD 67
PRK14293 PRK14293
molecular chaperone DnaJ;
344-413 1.20e-09

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 60.77  E-value: 1.20e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD-LGE 413
Cdd:PRK14293   1 MAADYYEILGVSRDADKDELKRAYRRLARKYHPDVNKEPG--AEDRFKEINRAYEVLSDPETRARYDqFGE 69
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 345-410 1.93e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 59.57  E-value: 1.93e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14299   3 YKDYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKSPG--AEEKFKEINEAYTVLSDPEKRRIYD 66
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 342-433 3.53e-09

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 59.45  E-value: 3.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575003694 342 NNMKrsYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKnlvmnQKFENISEAYQILGYENRRKLYDlgEYDE---TN 418
Cdd:PTZ00037  26 DNEK--LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP-----EKFKEISRAYEVLSDPEKRKIYD--EYGEeglEG 96

                         90
                 ....*....|....*
gi 575003694 419 KMIIIDPLIFFNLIF 433
Cdd:PTZ00037  97 GEQPADASDLFDLIF 111
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 344-410 3.92e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 59.17  E-value: 3.92e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14290   1 MAKDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYD 67
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 344-410 7.20e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 58.21  E-value: 7.20e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14301   2 SQRDYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPD-NPEAEQKFKEAAEAYEVLRDAEKRARYD 67
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 344-412 7.74e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 58.14  E-value: 7.74e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYDLG 412
Cdd:PRK14278   1 MARDYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPDEE--AQEKFKEISVAYEVLSDPEKRRIVDLG 67
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 346-410 1.14e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 57.69  E-value: 1.14e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 575003694 346 RSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14286   4 RSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKG-NKESEEKFKEATEAYEILRDPKKRQAYD 67
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 345-410 2.29e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 56.70  E-value: 2.29e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNK-DKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14294   3 KRDYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPgDKE--AEELFKEAAEAYEVLSDPKKRGIYD 67
PRK10266 PRK10266
curved DNA-binding protein;
346-410 6.00e-08

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 54.83  E-value: 6.00e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 575003694 346 RSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPD--AEARFKEVAEAWEVLSDEQRRAEYD 66
PRK14288 PRK14288
molecular chaperone DnaJ;
344-410 7.49e-08

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 55.08  E-value: 7.49e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNK-DKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14288   1 MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAgDKE--AEEKFKLINEAYGVLSDEKKRALYD 66
PRK14297 PRK14297
molecular chaperone DnaJ;
345-410 7.58e-08

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 55.17  E-value: 7.58e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14297   3 SKDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKG-NKEAEEKFKEINEAYQVLSDPQKKAQYD 67
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 348-410 8.82e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 54.85  E-value: 8.82e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 348 YYDILDVKEDSDINEIKRKFYNLSLKYYPkmnkDKN---LVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14284   3 YYTILGVSKTASPEEIKKAYRKLAVKYHP----DKNpgdAEAEKRFKEVSEAYEVLSDAQKRESYD 64
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 344-410 1.08e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 54.61  E-value: 1.08e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDkNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14285   1 MKRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKG-NKEAESIFKEATEAYEVLIDDNKRAQYD 66
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
344-412 1.16e-07

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 50.10  E-value: 1.16e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVMNQKFENISEAYQILGYENRRKLYDLG 412
Cdd:COG2214    3 DLKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKALAEELFQRLNEAYEVLSDPERRAEYDRE 71
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 348-410 1.48e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 54.12  E-value: 1.48e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 575003694 348 YYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14292   4 YYELLGVSRTASADEIKSAYRKLALKYHPDRNKEKG--AAEKFAQINEAYAVLSDAEKRAHYD 64
PRK14289 PRK14289
molecular chaperone DnaJ;
345-410 2.03e-07

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 53.68  E-value: 2.03e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNK-DKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14289   4 KRDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPgDKE--AEEKFKEAAEAYDVLSDPDKRSRYD 68
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 345-410 4.60e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 52.49  E-value: 4.60e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNLVMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14282   3 KKDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEQKFKEIQEAYEVLSDPQKRAMYD 68
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 345-410 4.80e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 52.70  E-value: 4.80e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14287   3 KRDYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKAPD--AEDKFKEVKEAYDTLSDPQKKAHYD 66
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 345-410 4.09e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 46.48  E-value: 4.09e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575003694 345 KRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14296   3 KKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSPD--AHDKMVEINEAADVLLDKDKRKQYD 66
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 344-410 4.94e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 46.16  E-value: 4.94e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575003694 344 MKRSYYDILDVKEDSDINEIKRKFYNLSLKYYPKMNKDKNlvMNQKFENISEAYQILGYENRRKLYD 410
Cdd:PRK14300   1 MSQDYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKD--AEKKFKEINAAYDVLKDEQKRAAYD 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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