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Conserved domains on  [gi|575003700|gb|ETW64109|]
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hypothetical protein PFMC_00133 [Plasmodium falciparum CAMP/Malaysia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATS super family cl21266
acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and ...
 57-104 2.90e-11

acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and relatively conserved acidic terminal segment of the Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1). this domain appears to be present in all variants of the highly polymorphic PfEMP1 proteins.


The actual alignment was detected with superfamily member pfam15445:

Pssm-ID: 373851 [Multi-domain]  Cd Length: 446  Bit Score: 58.28  E-value: 2.90e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 575003700   57 VLLEPTKRDTFN-------IPSGDT-HTNKFTDDDSNQLKQDFIYQYLQNIQKDLP 104
Cdd:pfam15445 115 VVLEPSKNNTNTpsdtqndIPSDDIpSTNKITDEEWNTLKHDFISNMLQNTQNDEP 170
 
Name Accession Description Interval E-value
ATS pfam15445
acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and ...
 57-104 2.90e-11

acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and relatively conserved acidic terminal segment of the Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1). this domain appears to be present in all variants of the highly polymorphic PfEMP1 proteins.


Pssm-ID: 373851 [Multi-domain]  Cd Length: 446  Bit Score: 58.28  E-value: 2.90e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 575003700   57 VLLEPTKRDTFN-------IPSGDT-HTNKFTDDDSNQLKQDFIYQYLQNIQKDLP 104
Cdd:pfam15445 115 VVLEPSKNNTNTpsdtqndIPSDDIpSTNKITDEEWNTLKHDFISNMLQNTQNDEP 170
PTZ00176 PTZ00176
erythrocyte membrane protein 1 (PfEMP1); Provisional
 57-102 2.71e-10

erythrocyte membrane protein 1 (PfEMP1); Provisional


Pssm-ID: 140204 [Multi-domain]  Cd Length: 1317  Bit Score: 55.81  E-value: 2.71e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 575003700   57 VLLEPTKRDTFN-IPSGDTHTNKFTDDDSNQLKQDFIYQYLQNIQKD 102
Cdd:PTZ00176 1003 VVLEPSKRDTQNdIPSDNTPSYKLTDEEWNQLKDDFISQYLPNTEPN 1049
 
Name Accession Description Interval E-value
ATS pfam15445
acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and ...
 57-104 2.90e-11

acidic terminal segments, variant surface antigen of PfEMP1; ATS is the intracellular and relatively conserved acidic terminal segment of the Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1). this domain appears to be present in all variants of the highly polymorphic PfEMP1 proteins.


Pssm-ID: 373851 [Multi-domain]  Cd Length: 446  Bit Score: 58.28  E-value: 2.90e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 575003700   57 VLLEPTKRDTFN-------IPSGDT-HTNKFTDDDSNQLKQDFIYQYLQNIQKDLP 104
Cdd:pfam15445 115 VVLEPSKNNTNTpsdtqndIPSDDIpSTNKITDEEWNTLKHDFISNMLQNTQNDEP 170
PTZ00176 PTZ00176
erythrocyte membrane protein 1 (PfEMP1); Provisional
 57-102 2.71e-10

erythrocyte membrane protein 1 (PfEMP1); Provisional


Pssm-ID: 140204 [Multi-domain]  Cd Length: 1317  Bit Score: 55.81  E-value: 2.71e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 575003700   57 VLLEPTKRDTFN-IPSGDTHTNKFTDDDSNQLKQDFIYQYLQNIQKD 102
Cdd:PTZ00176 1003 VVLEPSKRDTQNdIPSDNTPSYKLTDEEWNQLKDDFISQYLPNTEPN 1049
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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