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Conserved domains on  [gi|2078106353|gb|KAG8557340|]
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hypothetical protein GDO81_018419 [Engystomops pustulosus]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 333-382 3.06e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 80.88  E-value: 3.06e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 333 CANCQTTTTTLWRRNAN-GDPVCNACGLYFKLHNVNRPLTMKKEG-IQTRNR 382
Cdd:cd00202     2 CSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNR 53
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 278-328 1.24e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.24e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 278 ECVNCGATATPLWRRDG-TGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARR 328
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRN 52
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 333-382 3.06e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 80.88  E-value: 3.06e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 333 CANCQTTTTTLWRRNAN-GDPVCNACGLYFKLHNVNRPLTMKKEG-IQTRNR 382
Cdd:cd00202     2 CSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNR 53
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 278-328 1.24e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.24e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 278 ECVNCGATATPLWRRDG-TGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARR 328
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRN 52
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
328-377 2.66e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 75.53  E-value: 2.66e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353  328 RAGTCCANCQTTTTTLWRRNANGD-PVCNACGLYFKLHNV-NRPLTMKKEGI 377
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
275-322 2.83e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 67.06  E-value: 2.83e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2078106353  275 EGRECVNCGATATPLWRRDGTGH-YLCNACGLYHKMNGQ-NRPLIKPKRR 322
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 333-367 6.91e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 62.72  E-value: 6.91e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2078106353 333 CANCQTTTTTLWRRNANGDP-VCNACGLYFKLHNVN 367
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 279-313 2.12e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 61.18  E-value: 2.12e-12
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2078106353 279 CVNCGATATPLWRRDGTGHY-LCNACGLYHKMNGQN 313
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
281-382 9.85e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 54.11  E-value: 9.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2078106353 281 NCGATATPLWRR-DGTGHYLCNACGLYHKMNGQNRPLikPKRRLSAARRAGTCCANCQTTTTTLWRRNANGdpvCNACGL 359
Cdd:COG5641   303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPL--LPKPDPNSKRSNATCMNCSSTPTNKILSPPTT---SNSPGA 377

                          90       100
                  ....*....|....*....|...
gi 2078106353 360 YFKLHNVNRPLTMKKEGIQTRNR 382
Cdd:COG5641   378 QVKLPNQTRSTGATKKKITRRRM 400
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
279-362 9.66e-06

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 47.94  E-value: 9.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2078106353 279 CVNCGATATPLWRRD-----GTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTT-TTLWRRNANGDP 352
Cdd:COG5641   161 CSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISLKSDSIKSRSSRSSHNNNDSNGeNANTESIGNSSA 240

                          90
                  ....*....|
gi 2078106353 353 VCNACGLYFK 362
Cdd:COG5641   241 SKLTKSWEER 250
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 333-382 3.06e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 80.88  E-value: 3.06e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 333 CANCQTTTTTLWRRNAN-GDPVCNACGLYFKLHNVNRPLTMKKEG-IQTRNR 382
Cdd:cd00202     2 CSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDqIKRRNR 53
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 278-328 1.24e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.24e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353 278 ECVNCGATATPLWRRDG-TGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARR 328
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRN 52
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
328-377 2.66e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 75.53  E-value: 2.66e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2078106353  328 RAGTCCANCQTTTTTLWRRNANGD-PVCNACGLYFKLHNV-NRPLTMKKEGI 377
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
275-322 2.83e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 67.06  E-value: 2.83e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2078106353  275 EGRECVNCGATATPLWRRDGTGH-YLCNACGLYHKMNGQ-NRPLIKPKRR 322
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 333-367 6.91e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 62.72  E-value: 6.91e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2078106353 333 CANCQTTTTTLWRRNANGDP-VCNACGLYFKLHNVN 367
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 279-313 2.12e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 61.18  E-value: 2.12e-12
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2078106353 279 CVNCGATATPLWRRDGTGHY-LCNACGLYHKMNGQN 313
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
281-382 9.85e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 54.11  E-value: 9.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2078106353 281 NCGATATPLWRR-DGTGHYLCNACGLYHKMNGQNRPLikPKRRLSAARRAGTCCANCQTTTTTLWRRNANGdpvCNACGL 359
Cdd:COG5641   303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPL--LPKPDPNSKRSNATCMNCSSTPTNKILSPPTT---SNSPGA 377

                          90       100
                  ....*....|....*....|...
gi 2078106353 360 YFKLHNVNRPLTMKKEGIQTRNR 382
Cdd:COG5641   378 QVKLPNQTRSTGATKKKITRRRM 400
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
333-382 1.69e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 53.34  E-value: 1.69e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2078106353 333 CANCQTTTTTLWRR-----NANGDPVCNACGLYFKLHNVNR-PLTMKKEGIQTRNR 382
Cdd:COG5641   161 CSNCKTTSTPLWRRassesSLPGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRSS 216
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
279-362 9.66e-06

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 47.94  E-value: 9.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2078106353 279 CVNCGATATPLWRRD-----GTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTT-TTLWRRNANGDP 352
Cdd:COG5641   161 CSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISLKSDSIKSRSSRSSHNNNDSNGeNANTESIGNSSA 240

                          90
                  ....*....|
gi 2078106353 353 VCNACGLYFK 362
Cdd:COG5641   241 SKLTKSWEER 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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