![](files/infoQ.gif)
eukaryotic translation initiation factor 5A-1 [Bos taurus]
eukaryotic translation initiation factor 5A family protein( domain architecture ID 1904013)
eukaryotic translation initiation factor 5A (eIF-5A) family protein is a translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | |||
PLN03107 super family | cl42976 | eukaryotic translation initiation factor 5A; Provisional |
1-150 | 5.60e-73 | |||
eukaryotic translation initiation factor 5A; Provisional The actual alignment was detected with superfamily member PLN03107: Pssm-ID: 215580 Cd Length: 159 Bit Score: 215.73 E-value: 5.60e-73
|
|||||||
Name | Accession | Description | Interval | E-value | |||
PLN03107 | PLN03107 | eukaryotic translation initiation factor 5A; Provisional |
1-150 | 5.60e-73 | |||
eukaryotic translation initiation factor 5A; Provisional Pssm-ID: 215580 Cd Length: 159 Bit Score: 215.73 E-value: 5.60e-73
|
|||||||
eIF_5A | TIGR00037 | translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes ... |
14-150 | 2.04e-50 | |||
translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes and aIF5A in archaea, hypusine-containing proteins, from translation initiation factor to translation elongation factor. [Protein synthesis, Translation factors] Pssm-ID: 272866 [Multi-domain] Cd Length: 130 Bit Score: 157.68 E-value: 2.04e-50
|
|||||||
S1_eIF5A | cd04468 | S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. ... |
84-152 | 1.76e-35 | |||
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential for eIF5A function and is a post-translationally modified lysine. eIF5A interacts with components of the 80S ribosome and translation elongation factors 2 (eEF2) in a hypusine-dependent manner. This C-terminal S1 domain resembles the oligonucleotides-binding fold (OB fold) which binds RNA. Moreover, eIF5A prefers binding to the actively translating ribosome. This evidence suggests that eIF5A plays a role in translation elongation instead of translation initiation as previously proposed. Pssm-ID: 239914 Cd Length: 69 Bit Score: 117.64 E-value: 1.76e-35
|
|||||||
eIF-5a | pfam01287 | Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold; eIF5A, previously thought to be ... |
83-150 | 6.95e-29 | |||
Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold; eIF5A, previously thought to be an initiation factor, has been shown to be required for peptide chain elongation in yeast. Pssm-ID: 396035 Cd Length: 69 Bit Score: 100.73 E-value: 6.95e-29
|
|||||||
Name | Accession | Description | Interval | E-value | ||||
PLN03107 | PLN03107 | eukaryotic translation initiation factor 5A; Provisional |
1-150 | 5.60e-73 | ||||
eukaryotic translation initiation factor 5A; Provisional Pssm-ID: 215580 Cd Length: 159 Bit Score: 215.73 E-value: 5.60e-73
|
||||||||
PTZ00328 | PTZ00328 | eukaryotic initiation factor 5a; Provisional |
3-154 | 9.60e-52 | ||||
eukaryotic initiation factor 5a; Provisional Pssm-ID: 140349 [Multi-domain] Cd Length: 166 Bit Score: 162.15 E-value: 9.60e-52
|
||||||||
eIF_5A | TIGR00037 | translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes ... |
14-150 | 2.04e-50 | ||||
translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes and aIF5A in archaea, hypusine-containing proteins, from translation initiation factor to translation elongation factor. [Protein synthesis, Translation factors] Pssm-ID: 272866 [Multi-domain] Cd Length: 130 Bit Score: 157.68 E-value: 2.04e-50
|
||||||||
S1_eIF5A | cd04468 | S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. ... |
84-152 | 1.76e-35 | ||||
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential for eIF5A function and is a post-translationally modified lysine. eIF5A interacts with components of the 80S ribosome and translation elongation factors 2 (eEF2) in a hypusine-dependent manner. This C-terminal S1 domain resembles the oligonucleotides-binding fold (OB fold) which binds RNA. Moreover, eIF5A prefers binding to the actively translating ribosome. This evidence suggests that eIF5A plays a role in translation elongation instead of translation initiation as previously proposed. Pssm-ID: 239914 Cd Length: 69 Bit Score: 117.64 E-value: 1.76e-35
|
||||||||
eIF-5a | pfam01287 | Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold; eIF5A, previously thought to be ... |
83-150 | 6.95e-29 | ||||
Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold; eIF5A, previously thought to be an initiation factor, has been shown to be required for peptide chain elongation in yeast. Pssm-ID: 396035 Cd Length: 69 Bit Score: 100.73 E-value: 6.95e-29
|
||||||||
PRK03999 | PRK03999 | translation initiation factor IF-5A; Provisional |
25-94 | 4.20e-19 | ||||
translation initiation factor IF-5A; Provisional Pssm-ID: 235193 [Multi-domain] Cd Length: 129 Bit Score: 77.64 E-value: 4.20e-19
|
||||||||
Blast search parameters | ||||
|