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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform 2 [Homo sapiens]
LYR motif-containing protein( domain architecture ID 1563021)
LYR motif-containing protein may play a key role in the assembly and function of complexes I, II, and III; LYR motifs are molecular signatures of specific recipient Fe-S proteins or accessory factors that assist Fe-S cluster delivery; similar to Caenorhabditis elegans protein FMC1 homolog
List of domain hits
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Name | Accession | Description | Interval | E-value | ||
Complex1_LYR_SF super family | cl40429 | LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily; The ... |
1-32 | 1.10e-11 | ||
LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily; The Complex1_LYR-like superfamily consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. The human genome has at least ten LYR proteins that were predominantly identified as mitochondrial proteins. Some family members were also found in the cytosol or nucleus. LYR motif-containing protein 4 (LYRM4) represents the only LYR protein that is directly involved in the first steps of Fe-S cluster generation. Other LYR proteins have been identified as accessory subunits or assembly factors of mitochondrial OXPHOS (oxidative phosphorylation) complexes I, II, III and V, and they play specific roles in acetate metabolism. The actual alignment was detected with superfamily member cd20263: Pssm-ID: 477356 Cd Length: 77 Bit Score: 56.03 E-value: 1.10e-11
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Name | Accession | Description | Interval | E-value | ||
Complex1_LYR_NDUFB9_LYRM3 | cd20263 | LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta ... |
1-32 | 1.10e-11 | ||
LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins; NDUFB9, also called LYR motif-containing protein 3 (LYRM3), or Complex I-B22 (CI-B22), or NADH-ubiquinone oxidoreductase B22 subunit (UQOR22), is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I), and is believed to be not involved in catalysis. In general, accessory subunits are integral for assembly and function of Complex I, which functions in the transfer of electrons from NADH to the respiratory chain. NDUFB9 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380758 Cd Length: 77 Bit Score: 56.03 E-value: 1.10e-11
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Name | Accession | Description | Interval | E-value | ||
Complex1_LYR_NDUFB9_LYRM3 | cd20263 | LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta ... |
1-32 | 1.10e-11 | ||
LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins; NDUFB9, also called LYR motif-containing protein 3 (LYRM3), or Complex I-B22 (CI-B22), or NADH-ubiquinone oxidoreductase B22 subunit (UQOR22), is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I), and is believed to be not involved in catalysis. In general, accessory subunits are integral for assembly and function of Complex I, which functions in the transfer of electrons from NADH to the respiratory chain. NDUFB9 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380758 Cd Length: 77 Bit Score: 56.03 E-value: 1.10e-11
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Blast search parameters | ||||
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