NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1012519614|ref|NP_001308780|]
View 

thyroid receptor-interacting protein 11 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1234 2.04e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  393 LSDAENEIMR-LSSLNQDNSLAEDNLKLKMRIEvlEKEKSLLSQEKEELQMSLLKLN---NEYEVIKSTATRDIS-LDSE 467
Cdd:TIGR02168  191 LEDILNELERqLKSLERQAEKAERYKELKAELR--ELELALLVLRLEELREELEELQeelKEAEEELEELTAELQeLEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  468 LHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMilikDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLED 547
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL----ANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  548 DKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELM 627
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  628 QSLNQDSNSNFKDT---------LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKL---VLACEDVRHQLE-- 693
Cdd:TIGR02168  425 ELLKKLEEAELKELqaeleeleeELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarLDSLERLQENLEgf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  694 -----ECLAGNNQLSLEKNTIVETLKMEKG---EIEAELCWAKKRLL-EEANKYEKTIEELSNARNLNTSALQLEHEHLI 764
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELISVDEGyeaAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  765 KLnQKKDMEIAELKKNIEQMDTDHKETKDVLS-------------SSLEEQKQLTQLINKKEIFI----EKLKERSSKLQ 827
Cdd:TIGR02168  585 EI-QGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGYRIVtldgDLVRPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  828 EELDKYSQAL-RKNEI--LRQTIEEKDRSLGSMKEENNhlqeelerlreeqsrtapvadpKTLDSVTELASEVSQLNTIK 904
Cdd:TIGR02168  664 GSAKTNSSILeRRREIeeLEEKIEELEEKIAELEKALA----------------------ELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  905 EHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDE---EIKSLQKTIEQIKTQLHEE 981
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  982 RQDIqTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLvkgIKERELEIKLLNEKNISLTKQIDQLskdevgkltqiiq 1061
Cdd:TIGR02168  802 REAL-DELRAELTLLNEEAANLRERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEEL------------- 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1062 qkDLEIQALHARIssTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKK 1141
Cdd:TIGR02168  865 --EELIEELESEL--EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1142 LSTRFESSGQDMFRETIQNLSriirekdiEIDALSQKCQTLLAVLQTSStgNEAGGVNSN---QFEELLQERDKLKQQVK 1218
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALEN--------KIEDDEEEARRRLKRLENKI--KELGPVNLAaieEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*.
gi 1012519614 1219 KMEEWKQQVMTTVQNM 1234
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEI 1026
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 907-1751 7.70e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 7.70e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  907 LEEEIKHHQKII-----EDQNQSKMQLLQSLQEQKKEMDEFRyqhEQMNATHTQL------FLEKDEEIKSLQKTIEQIK 975
Cdd:TIGR02168  218 LKAELRELELALlvlrlEELREELEELQEELKEAEEELEELT---AELQELEEKLeelrleVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  976 TQLHEERQDIQ-TDNSDIFQETKVQSLN--IENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDE 1052
Cdd:TIGR02168  295 NEISRLEQQKQiLRERLANLERQLEELEaqLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1053 VGKLTQIIQQKDLEIQALHARissTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMdiVAAKEAAL 1132
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQI---ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1133 IKLQDENKKLSTRFESSgqdmfRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDK 1212
Cdd:TIGR02168  450 EELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1213 LKQQVKKMEEWKQQVmttvqnmqheSAQLQEELhqlqaQVLVDSDNNSKLQvdytgLIQSYEQNETKLKNF-------GQ 1285
Cdd:TIGR02168  525 LSELISVDEGYEAAI----------EAALGGRL-----QAVVVENLNAAKK-----AIAFLKQNELGRVTFlpldsikGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1286 ELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSAslLTPQSAECLRASksevlsesselLQQELEELRKSLQEKdATIRTL 1365
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA--LSYLLGGVLVVD-----------DLDNALELAKKLRPG-YRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1366 QENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTN 1445
Cdd:TIGR02168  651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1446 LKERILILEMDIGKLkgenekivetyrgkETEYQALQETNMKfsmmLREKEFECHSMKEKALAFEQLLKEKEQGKTGELN 1525
Cdd:TIGR02168  731 LRKDLARLEAEVEQL--------------EERIAQLSKELTE----LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1526 QLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRnhllESEDSYTREALAAEDRE 1605
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS----EDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1606 AKLRKKVTVLEEKLvsssNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQE 1685
Cdd:TIGR02168  869 EELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1686 EKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEAN----AALDSASRLTEQLDVKEEQIEELKR 1751
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvnlAAIEEYEELKERYDFLTAQKEDLTE 1014
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
170-544 1.30e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  170 QQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRsQEIDDHQHEMSVLQNAHQQKLTEI 249
Cdd:COG4717    108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELE-EELEELEAELAELQEELEELLEQL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  250 SRRHREELSDYEERIEELENLLQQggsgvIETDLSKIYEMQKTIQVlQIEKVESTKKMEQLEDKIKD------------- 316
Cdd:COG4717    187 SLATEEELQDLAEELEELQQRLAE-----LEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEarlllliaaalla 260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  317 --------------------------------INKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLecsklqpsav 364
Cdd:COG4717    261 llglggsllsliltiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGL---------- 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  365 kqsDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSL-----AEDNLKLKMRIEVLEKEKSLLsQEKEE 439
Cdd:COG4717    331 ---PPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlaeagVEDEEELRAALEQAEEYQELK-EELEE 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  440 LQMSLLKLNNEYEVIKSTATRDiSLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQ-EATKHMILIKDQLS 518
Cdd:COG4717    407 LEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAEL 485

                          410       420
                   ....*....|....*....|....*.
gi 1012519614  519 KQQNEGDSIISKLKQDLNDEKKRVHQ 544
Cdd:COG4717    486 RELAEEWAALKLALELLEEAREEYRE 511
GRAB super family cl11041
GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type ...
 1773-1818 8.19e-04

GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type proteins. This domain is related to the GRIP domain, but the conserved tyrosine residue found at position 4 in all GRIP domains is replaced by a leucine residue. The Arf small GTPase is localized to the cis-Golgi where it recruits proteins via their GRAB domain, as part of the transport of cargo from the endoplasmic reticulum to the plasma membrane.


The actual alignment was detected with superfamily member pfam10375:

Pssm-ID: 431241  Cd Length: 49  Bit Score: 39.13  E-value: 8.19e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1012519614 1773 SSEGKVDKVLMRNLFIGHFHTPK--NQRHEVLRLMGSILGVRREEMEQ 1818
Cdd:pfam10375    1 SSEDTVDRQLVTNLLLSFLSIPRgdTKKFEILQLIANLLEWDDEQREQ 48
bHLH_SF super family cl00081
basic Helix Loop Helix (bHLH) domain superfamily; bHLH proteins are transcriptional regulators ...
 63-122 6.71e-03

basic Helix Loop Helix (bHLH) domain superfamily; bHLH proteins are transcriptional regulators that are found in organisms from yeast to humans. Members of the bHLH superfamily have two highly conserved and functionally distinct regions. The basic part is at the amino end of the bHLH that may bind DNA to a consensus hexanucleotide sequence known as the E box (CANNTG). Different families of bHLH proteins recognize different E-box consensus sequences. At the carboxyl-terminal end of the region is the HLH region that interacts with other proteins to form homo- and heterodimers. bHLH proteins function as a diverse set of regulatory factors because they recognize different DNA sequences and dimerize with different proteins. The bHLH proteins can be divided to cell-type specific and widely expressed proteins. The cell-type specific members of bHLH superfamily are involved in cell-fate determination and act in neurogenesis, cardiogenesis, myogenesis, and hematopoiesis.


The actual alignment was detected with superfamily member cd11400:

Pssm-ID: 469605 [Multi-domain]  Cd Length: 80  Bit Score: 37.53  E-value: 6.71e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   63 LRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLK 122
Cdd:cd11400     16 LKNSFEKLRDLVPELADNEKASKVVILKKATEYIKQLQQEEKKLEKEKDKLKARNEQLRK 75
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1234 2.04e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  393 LSDAENEIMR-LSSLNQDNSLAEDNLKLKMRIEvlEKEKSLLSQEKEELQMSLLKLN---NEYEVIKSTATRDIS-LDSE 467
Cdd:TIGR02168  191 LEDILNELERqLKSLERQAEKAERYKELKAELR--ELELALLVLRLEELREELEELQeelKEAEEELEELTAELQeLEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  468 LHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMilikDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLED 547
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL----ANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  548 DKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELM 627
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  628 QSLNQDSNSNFKDT---------LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKL---VLACEDVRHQLE-- 693
Cdd:TIGR02168  425 ELLKKLEEAELKELqaeleeleeELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarLDSLERLQENLEgf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  694 -----ECLAGNNQLSLEKNTIVETLKMEKG---EIEAELCWAKKRLL-EEANKYEKTIEELSNARNLNTSALQLEHEHLI 764
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELISVDEGyeaAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  765 KLnQKKDMEIAELKKNIEQMDTDHKETKDVLS-------------SSLEEQKQLTQLINKKEIFI----EKLKERSSKLQ 827
Cdd:TIGR02168  585 EI-QGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGYRIVtldgDLVRPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  828 EELDKYSQAL-RKNEI--LRQTIEEKDRSLGSMKEENNhlqeelerlreeqsrtapvadpKTLDSVTELASEVSQLNTIK 904
Cdd:TIGR02168  664 GSAKTNSSILeRRREIeeLEEKIEELEEKIAELEKALA----------------------ELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  905 EHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDE---EIKSLQKTIEQIKTQLHEE 981
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  982 RQDIqTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLvkgIKERELEIKLLNEKNISLTKQIDQLskdevgkltqiiq 1061
Cdd:TIGR02168  802 REAL-DELRAELTLLNEEAANLRERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEEL------------- 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1062 qkDLEIQALHARIssTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKK 1141
Cdd:TIGR02168  865 --EELIEELESEL--EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1142 LSTRFESSGQDMFRETIQNLSriirekdiEIDALSQKCQTLLAVLQTSStgNEAGGVNSN---QFEELLQERDKLKQQVK 1218
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALEN--------KIEDDEEEARRRLKRLENKI--KELGPVNLAaieEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*.
gi 1012519614 1219 KMEEWKQQVMTTVQNM 1234
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEI 1026
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 297-1146 2.27e-15

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 82.71  E-value: 2.27e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  297 QIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERI 376
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  377 LAQSasveevFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKlKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKS 456
Cdd:pfam02463  249 EQEE------IESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ-EEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  457 TATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLN 536
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  537 DEKKRV---HQLEDDKMDITKELDVQKEKL---IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKE 610
Cdd:pfam02463  402 EEEKEAqllLELARQLEDLLKEEKKEELEIleeEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  611 HIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRH 690
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  691 QLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKK 770
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  771 DMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQaLRKNEILRQTIEEK 850
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ-REKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  851 DRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQ 930
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  931 -SLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEK 1009
Cdd:pfam02463  801 eELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1010 HDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQ-----QKDLEIQALHARISSTSHTQDVV 1084
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKyeeepEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614 1085 YLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRF 1146
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 422-978 5.28e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 5.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  422 RIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRdisLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDR 501
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEE---LRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  502 QNQEATKHmiliKDQLSKQQNEgdsiiskLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLE 581
Cdd:COG1196    310 RRRELEER----LEELEEELAE-------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  582 DKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDsnsnfkDTLLKEREAEVRNLKQNLSELE 661
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL------AELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  662 QLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKT 741
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  742 IEELSNArnLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKE 821
Cdd:COG1196    533 EAAYEAA--LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  822 RSSK-------LQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQS--RTAPVADPKTLDSVTE 892
Cdd:COG1196    611 ADARyyvlgdtLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAalLEAEAELEELAERLAE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  893 LASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIE 972
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770


                   ....*.
gi 1012519614  973 QIKTQL 978
Cdd:COG1196    771 RLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 907-1751 7.70e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 7.70e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  907 LEEEIKHHQKII-----EDQNQSKMQLLQSLQEQKKEMDEFRyqhEQMNATHTQL------FLEKDEEIKSLQKTIEQIK 975
Cdd:TIGR02168  218 LKAELRELELALlvlrlEELREELEELQEELKEAEEELEELT---AELQELEEKLeelrleVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  976 TQLHEERQDIQ-TDNSDIFQETKVQSLN--IENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDE 1052
Cdd:TIGR02168  295 NEISRLEQQKQiLRERLANLERQLEELEaqLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1053 VGKLTQIIQQKDLEIQALHARissTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMdiVAAKEAAL 1132
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQI---ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1133 IKLQDENKKLSTRFESSgqdmfRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDK 1212
Cdd:TIGR02168  450 EELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1213 LKQQVKKMEEWKQQVmttvqnmqheSAQLQEELhqlqaQVLVDSDNNSKLQvdytgLIQSYEQNETKLKNF-------GQ 1285
Cdd:TIGR02168  525 LSELISVDEGYEAAI----------EAALGGRL-----QAVVVENLNAAKK-----AIAFLKQNELGRVTFlpldsikGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1286 ELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSAslLTPQSAECLRASksevlsesselLQQELEELRKSLQEKdATIRTL 1365
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA--LSYLLGGVLVVD-----------DLDNALELAKKLRPG-YRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1366 QENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTN 1445
Cdd:TIGR02168  651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1446 LKERILILEMDIGKLkgenekivetyrgkETEYQALQETNMKfsmmLREKEFECHSMKEKALAFEQLLKEKEQGKTGELN 1525
Cdd:TIGR02168  731 LRKDLARLEAEVEQL--------------EERIAQLSKELTE----LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1526 QLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRnhllESEDSYTREALAAEDRE 1605
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS----EDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1606 AKLRKKVTVLEEKLvsssNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQE 1685
Cdd:TIGR02168  869 EELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1686 EKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEAN----AALDSASRLTEQLDVKEEQIEELKR 1751
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvnlAAIEEYEELKERYDFLTAQKEDLTE 1014
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
212-829 1.95e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 1.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  212 KLQNIIKELKQNRSQEIDDHQHEMSV--LQNAHQQKLTEISRRHREELSDYEERIEELENLlqqggsgviETDLSKIYEM 289
Cdd:PRK03918   166 NLGEVIKEIKRRIERLEKFIKRTENIeeLIKEKEKELEEVLREINEISSELPELREELEKL---------EKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  290 QKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSsaendrdilrreqeqlnvEKRQIMEECENLKLECSKLQPSAVKQSDT 369
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIE------------------ELKKEIEELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 MTEKERILAQSASVEEvfRLQQALSDAENEIMRLSSLNQDNSLAEdnlKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 449
Cdd:PRK03918   299 SEFYEEYLDELREIEK--RLSRLEEEINGIEERIKELEEKEERLE---ELKKKLKELEKRLEELEERHELYEEAKAKKEE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  450 EYEVIKSTATRDIS-LDSELHDL---RLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGd 525
Cdd:PRK03918   374 LERLKKRLTGLTPEkLEKELEELekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKE- 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  526 sIISKLKQDLNDEKKRVHQLEDDKMDITKELdVQKEKLIQSEVALNDLHltkqKLEDKVENLVDQLNKSQESNVSIQKEN 605
Cdd:PRK03918   453 -LLEEYTAELKRIEKELKEIEEKERKLRKEL-RELEKVLKKESELIKLK----ELAEQLKELEEKLKKYNLEELEKKAEE 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  606 LE-LKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSEL-----EQLNENLKKVAfdvKMENE 679
Cdd:PRK03918   527 YEkLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesvEELEERLKELE---PFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  680 KLVLacEDVRHQLEECLagnNQLSLEKNTIVETLKmEKGEIEAELCWAKKRLLEEANKYEKtiEELSNARNLNTSalqLE 759
Cdd:PRK03918   604 YLEL--KDAEKELEREE---KELKKLEEELDKAFE-ELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLE---LS 672

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614  760 HEHLIKLNQKKDME--IAELKKNIEQMdtdhKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEE 829
Cdd:PRK03918   673 RELAGLRAELEELEkrREEIKKTLEKL----KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1352-1680 1.63e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1352 RKSLQEKDATIRTLQENNHRLSDSIAATSELERKEhEQTDSEIKQLKEKQDV----LQKLLKEKDLLIKAKSdQLLSSNE 1427
Cdd:pfam15921  478 RKVVEELTAKKMTLESSERTVSDLTASLQEKERAI-EATNAEITKLRSRVDLklqeLQHLKNEGDHLRNVQT-ECEALKL 555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1428 NFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKE-----FECHSM 1502
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsdLELEKV 635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1503 KEKALAFEQLLKEKEQGKtgELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMEntaLQNEVQRLRDKEFRSNQELER 1582
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQ--ERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEE---METTTNKLKMQLKSAQSELEQ 710

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1583 LRNHL--LESEDSYT-REALAAEDREAKLRKKVTVLEEKLVSSSNAMENAS---HQASVQVESLQEQLNVVSKQRDETAL 1656
Cdd:pfam15921  711 TRNTLksMEGSDGHAmKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANkekHFLKEEKNKLSQELSTVATEKNKMAG 790

                          330       340
                   ....*....|....*....|....
gi 1012519614 1657 QLSVSQEQVKQYALSLANLQMVLE 1680
Cdd:pfam15921  791 ELEVLRSQERRLKEKVANMEVALD 814
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1502-1764 1.45e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1502 MKEKALAFEQLLKEKEQgKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1581
Cdd:COG1196    248 LEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1582 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVS 1661
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1662 QEQVKQYALSLANLQMVLEHFQQEEKAmySAELEKQKQLIAEWKKNAENLEGKVISLQECLDEanaALDSASRLTEQLDV 1741
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAEL--EEEEEEEEEALEEAAEEEAELEEEEEALLELLAE---LLEEAALLEAALAE 481

                          250       260
                   ....*....|....*....|...
gi 1012519614 1742 KEEQIEELKRQNELRQEMLDDVQ 1764
Cdd:COG1196    482 LLEELAEAAARLLLLLEAEADYE 504
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1362-1770 1.19e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1362 IRTLQENNHRLSDSIAATSELERKEHEQTDS---EIKQLKEKQDVLQKLLKEKDLLIKAKSDqLLSSNENFTNKVNENEL 1438
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKEleeVLREINEISSELPELREELEKLEKEVKE-LEELKEEIEELEKELES 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1439 LRQAVTNLKERILILEMDIGKLKG------ENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQL 1512
Cdd:PRK03918   250 LEGSKRKLEEKIRELEERIEELKKeieeleEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1513 LKEKEQgKTGELNQLLNAVKSMQEKTVVFQqERDQVMLALKQKQMENTALQNEVQRLR-DKEFRSNQELERLRNHLLESE 1591
Cdd:PRK03918   330 IKELEE-KEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1592 DSYTREALAAEDREAKLRKKVTVLEE-KLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYAL 1670
Cdd:PRK03918   408 SKITARIGELKKEIKELKKAIEELKKaKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1671 SLANLQMV---------LEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDV 1741
Cdd:PRK03918   488 VLKKESELiklkelaeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDE 567

                          410       420       430
                   ....*....|....*....|....*....|
gi 1012519614 1742 KEEQIEELKRQ-NELRQEMLDDVQKKLMSL 1770
Cdd:PRK03918   568 LEEELAELLKElEELGFESVEELEERLKEL 597
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
170-544 1.30e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  170 QQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRsQEIDDHQHEMSVLQNAHQQKLTEI 249
Cdd:COG4717    108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELE-EELEELEAELAELQEELEELLEQL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  250 SRRHREELSDYEERIEELENLLQQggsgvIETDLSKIYEMQKTIQVlQIEKVESTKKMEQLEDKIKD------------- 316
Cdd:COG4717    187 SLATEEELQDLAEELEELQQRLAE-----LEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEarlllliaaalla 260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  317 --------------------------------INKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLecsklqpsav 364
Cdd:COG4717    261 llglggsllsliltiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGL---------- 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  365 kqsDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSL-----AEDNLKLKMRIEVLEKEKSLLsQEKEE 439
Cdd:COG4717    331 ---PPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlaeagVEDEEELRAALEQAEEYQELK-EELEE 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  440 LQMSLLKLNNEYEVIKSTATRDiSLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQ-EATKHMILIKDQLS 518
Cdd:COG4717    407 LEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAEL 485

                          410       420
                   ....*....|....*....|....*.
gi 1012519614  519 KQQNEGDSIISKLKQDLNDEKKRVHQ 544
Cdd:COG4717    486 RELAEEWAALKLALELLEEAREEYRE 511
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 204-441 1.39e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  204 NSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDL 283
Cdd:pfam12128  660 DEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIA 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  284 SKIYEMQKTIQVLQIEKVESTKK-------MEQLEDKIKDINKKLSSAENDRDILRR----EQEQLNVEKRQIMEECENL 352
Cdd:pfam12128  740 ARRSGAKAELKALETWYKRDLASlgvdpdvIAKLKREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNI 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  353 KLECSKLQPS-AVKQSDTMTEKERILAQS-ASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEK 430
Cdd:pfam12128  820 ERAISELQQQlARLIADTKLRRAKLEMERkASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLK 899

                          250
                   ....*....|.
gi 1012519614  431 SLLSQEKEELQ 441
Cdd:pfam12128  900 LKRDYLSESVK 910
GRAB pfam10375
GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type ...
 1773-1818 8.19e-04

GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type proteins. This domain is related to the GRIP domain, but the conserved tyrosine residue found at position 4 in all GRIP domains is replaced by a leucine residue. The Arf small GTPase is localized to the cis-Golgi where it recruits proteins via their GRAB domain, as part of the transport of cargo from the endoplasmic reticulum to the plasma membrane.


Pssm-ID: 431241  Cd Length: 49  Bit Score: 39.13  E-value: 8.19e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1012519614 1773 SSEGKVDKVLMRNLFIGHFHTPK--NQRHEVLRLMGSILGVRREEMEQ 1818
Cdd:pfam10375    1 SSEDTVDRQLVTNLLLSFLSIPRgdTKKFEILQLIANLLEWDDEQREQ 48
bHLHzip_Myc cd11400
basic Helix-Loop-Helix-zipper (bHLHzip) domain found in the Myc family; The Myc family is a ...
 63-122 6.71e-03

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in the Myc family; The Myc family is a member of the bHLHzip family of transcription factors that play important roles in the control of normal cell proliferation, growth, survival and differentiation. All Myc isoforms contain two independently functioning polypeptide chain regions: N-terminal transactivating residues and a C-terminal bHLHzip segment. The bHLHzip family of bHLH transcription factors are characterized by a highly conserved N-terminal basic region that may bind DNA at a consensus hexanucleotide sequence known as the E-box (CANNTG) followed by HLH and leucine zipper motifs that may interact with other proteins to form homo- and heterodimers. Myc heterodimerizes with Max enabling specific binding to E-box DNA sequences in the promoters of target genes. The Myc proto-oncoprotein family includes at least five different functional members: c-, N-, L-, S- and B-Myc (which is lacking the bHLH domain).


Pssm-ID: 381406 [Multi-domain]  Cd Length: 80  Bit Score: 37.53  E-value: 6.71e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   63 LRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLK 122
Cdd:cd11400     16 LKNSFEKLRDLVPELADNEKASKVVILKKATEYIKQLQQEEKKLEKEKDKLKARNEQLRK 75
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1234 2.04e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  393 LSDAENEIMR-LSSLNQDNSLAEDNLKLKMRIEvlEKEKSLLSQEKEELQMSLLKLN---NEYEVIKSTATRDIS-LDSE 467
Cdd:TIGR02168  191 LEDILNELERqLKSLERQAEKAERYKELKAELR--ELELALLVLRLEELREELEELQeelKEAEEELEELTAELQeLEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  468 LHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMilikDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLED 547
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL----ANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  548 DKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELM 627
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  628 QSLNQDSNSNFKDT---------LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKL---VLACEDVRHQLE-- 693
Cdd:TIGR02168  425 ELLKKLEEAELKELqaeleeleeELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarLDSLERLQENLEgf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  694 -----ECLAGNNQLSLEKNTIVETLKMEKG---EIEAELCWAKKRLL-EEANKYEKTIEELSNARNLNTSALQLEHEHLI 764
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELISVDEGyeaAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  765 KLnQKKDMEIAELKKNIEQMDTDHKETKDVLS-------------SSLEEQKQLTQLINKKEIFI----EKLKERSSKLQ 827
Cdd:TIGR02168  585 EI-QGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGYRIVtldgDLVRPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  828 EELDKYSQAL-RKNEI--LRQTIEEKDRSLGSMKEENNhlqeelerlreeqsrtapvadpKTLDSVTELASEVSQLNTIK 904
Cdd:TIGR02168  664 GSAKTNSSILeRRREIeeLEEKIEELEEKIAELEKALA----------------------ELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  905 EHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDE---EIKSLQKTIEQIKTQLHEE 981
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  982 RQDIqTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLvkgIKERELEIKLLNEKNISLTKQIDQLskdevgkltqiiq 1061
Cdd:TIGR02168  802 REAL-DELRAELTLLNEEAANLRERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEEL------------- 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1062 qkDLEIQALHARIssTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKK 1141
Cdd:TIGR02168  865 --EELIEELESEL--EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1142 LSTRFESSGQDMFRETIQNLSriirekdiEIDALSQKCQTLLAVLQTSStgNEAGGVNSN---QFEELLQERDKLKQQVK 1218
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALEN--------KIEDDEEEARRRLKRLENKI--KELGPVNLAaieEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*.
gi 1012519614 1219 KMEEWKQQVMTTVQNM 1234
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 243-1067 9.28e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.28e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  243 QQKLTEISRRHREELS---------DYEERIEELENLLQQggsgvIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDK 313
Cdd:TIGR02168  208 QAEKAERYKELKAELRelelallvlRLEELREELEELQEE-----LKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  314 IKDINKKLSSaendrdiLRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFR----- 388
Cdd:TIGR02168  283 IEELQKELYA-------LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKeeles 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  389 LQQALSDAENEIMRLSSLNQD-----NSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEvikstATRDIS 463
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEEleeqlETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE-----ELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  464 LDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISkLKQDLNDEKKRVH 543
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-LQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  544 QLEDDKMDITKELDVQKEKL---IQSEVALNDLhltkqkLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRqneeELS 620
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELIsvdEGYEAAIEAA------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFL----PLD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  621 RIRNELMQSLNQDSNSNFKDTL-----LKEREAEVRNLKQNL-------SELEQLNENLKKVAFDVKM------------ 676
Cdd:TIGR02168  580 SIKGTEIQGNDREILKNIEGFLgvakdLVKFDPKLRKALSYLlggvlvvDDLDNALELAKKLRPGYRIvtldgdlvrpgg 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  677 -------ENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEeankyektIEELSNAR 749
Cdd:TIGR02168  660 vitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE--------LSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  750 NLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEE 829
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  830 L----DKYSQALRKNEILRQTIEEKDRSLGSMKEENNhlqeelerlreeqsrtapvadpKTLDSVTELASEVSQLNTIKE 905
Cdd:TIGR02168  812 LtllnEEAANLRERLESLERRIAATERRLEDLEEQIE----------------------ELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  906 HLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQheqmnathtqlFLEKDEEIKSLQKTIEQIKTQLHEERQDI 985
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESK-----------RSELRRELEELREKLAQLELRLEGLEVRI 938

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  986 QTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKER-----------ELEIKLLNEKNISLTKQIDQLSKdEVG 1054
Cdd:TIGR02168  939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKikelgpvnlaaIEEYEELKERYDFLTAQKEDLTE-AKE 1017

                          890
                   ....*....|...
gi 1012519614 1055 KLTQIIQQKDLEI 1067
Cdd:TIGR02168 1018 TLEEAIEEIDREA 1030
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 297-1146 2.27e-15

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 82.71  E-value: 2.27e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  297 QIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERI 376
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  377 LAQSasveevFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKlKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKS 456
Cdd:pfam02463  249 EQEE------IESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ-EEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  457 TATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLN 536
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  537 DEKKRV---HQLEDDKMDITKELDVQKEKL---IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKE 610
Cdd:pfam02463  402 EEEKEAqllLELARQLEDLLKEEKKEELEIleeEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  611 HIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRH 690
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  691 QLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKK 770
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  771 DMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQaLRKNEILRQTIEEK 850
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ-REKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  851 DRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQ 930
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  931 -SLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEK 1009
Cdd:pfam02463  801 eELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1010 HDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQ-----QKDLEIQALHARISSTSHTQDVV 1084
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKyeeepEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614 1085 YLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRF 1146
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 225-985 1.92e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 1.92e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  225 SQEIDDHQHEMSVLQ-NAHQQKLteisRRHREELSDYEERIEELENLLQQGGSGVIETDLsKIYEMQKTIQVLQ------ 297
Cdd:TIGR02168  219 KAELRELELALLVLRlEELREEL----EELQEELKEAEEELEELTAELQELEEKLEELRL-EVSELEEEIEELQkelyal 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  298 ---IEKVESTK-----KMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDT 369
Cdd:TIGR02168  294 aneISRLEQQKqilreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 MTEKERILAQSASveEVFRLQQALSDAENEIMRLSSlnQDNSLAEDNLKLKMRIEVLEKEksLLSQEKEELQMSLLKLNn 449
Cdd:TIGR02168  374 LEELEEQLETLRS--KVAQLELQIASLNNEIERLEA--RLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELE- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  450 eyEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKdQLSKQQNEGDSIIS 529
Cdd:TIGR02168  447 --EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-ALLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  530 KLKQDLNDEKK-----------RVHQLEDDKMDITK-----------------ELDVQKEKLIQSE------------VA 569
Cdd:TIGR02168  524 VLSELISVDEGyeaaieaalggRLQAVVVENLNAAKkaiaflkqnelgrvtflPLDSIKGTEIQGNdreilkniegflGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  570 LNDLHLTKQKLEDKVENLVDQLN--KSQESNVSIQKENLELKEHIRQNEEELSR-------IRNELMQSLNQDSNSNFKD 640
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLvvDDLDNALELAKKLRPGYRIVTLDGDLVRPggvitggSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  641 TLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEI 720
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  721 E------AELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQkkdmEIAELKKNIEQMDTDHKETKDV 794
Cdd:TIGR02168  764 EeleerlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE----EAANLRERLESLERRIAATERR 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  795 LSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLgsMKEENNHLQEELERLREE 874
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL--SEELRELESKRSELRREL 917

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  875 QSRTAPVAdpktlDSVTELASEVSQLNTIKEHL-------EEEIKHHQKIIEDQNQSKMQLLQSLQEQKKE--------M 939
Cdd:TIGR02168  918 EELREKLA-----QLELRLEGLEVRIDNLQERLseeysltLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaI 992

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1012519614  940 DEFRYQHEQMNathtqlFLEK-----DEEIKSLQKTIEQIKTQLHEERQDI 985
Cdd:TIGR02168  993 EEYEELKERYD------FLTAqkedlTEAKETLEEAIEEIDREARERFKDT 1037
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 422-978 5.28e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 5.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  422 RIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRdisLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDR 501
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEE---LRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  502 QNQEATKHmiliKDQLSKQQNEgdsiiskLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLE 581
Cdd:COG1196    310 RRRELEER----LEELEEELAE-------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  582 DKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDsnsnfkDTLLKEREAEVRNLKQNLSELE 661
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL------AELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  662 QLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKT 741
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  742 IEELSNArnLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKE 821
Cdd:COG1196    533 EAAYEAA--LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  822 RSSK-------LQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQS--RTAPVADPKTLDSVTE 892
Cdd:COG1196    611 ADARyyvlgdtLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAalLEAEAELEELAERLAE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  893 LASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIE 972
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770


                   ....*.
gi 1012519614  973 QIKTQL 978
Cdd:COG1196    771 RLEREI 776
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 481-1032 6.74e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 73.90  E-value: 6.74e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  481 ELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSI---ISKLKQDLNDEKKRVHQLEDDKMDITKELD 557
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLnnkYNDLKKQKEELENELNLLEKEKLNIQKNID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  558 VQKEKLIQSEVALNDLHLTKQK---LEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDS 634
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKnksLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  635 NSNFK----DTLLKEREAEVRNLKQNLSELEQLNEN--LKKVAFDVKMENEKLVlacedvrhQLEECLAGNNQLSLEKNT 708
Cdd:TIGR04523  271 EKQKEleqnNKKIKELEKQLNQLKSEISDLNNQKEQdwNKELKSELKNQEKKLE--------EIQNQISQNNKIISQLNE 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  709 IVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEE----LSNARNLNT--SALQLEHEHLIKLNQKKDMEIAELKKNIE 782
Cdd:TIGR04523  343 QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKEnqsyKQEIKNLESqiNDLESKIQNQEKLNQQKDEQIKKLQQEKE 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  783 QMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKN----EILRQTIEEKDRSLGSMK 858
Cdd:TIGR04523  423 LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIkqnlEQKQKELKSKEKELKKLN 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  859 EENNHLQEELERLREEQSrtapvadpKTLDSVTELASEVSQLNTIKEHLEEEIKHhqkiiEDQNQSKMQLLQSLQEQKKE 938
Cdd:TIGR04523  503 EEKKELEEKVKDLTKKIS--------SLKEKIEKLESEKKEKESKISDLEDELNK-----DDFELKKENLEKEIDEKNKE 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  939 MDEFRYQHEQMNATHTqlflEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIfQETKVQSLNIENGSEKHDLSKAETE 1018
Cdd:TIGR04523  570 IEELKQTQKSLKKKQE----EKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL-EKAKKENEKLSSIIKNIKSKKNKLK 644

                          570
                   ....*....|....
gi 1012519614 1019 RLVKGIKERELEIK 1032
Cdd:TIGR04523  645 QEVKQIKETIKEIR 658
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 411-724 1.04e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  411 SLAEDNLKLKMRIEVLEKEKSLLSQEKEELQmsllKLNNEYEVIKSTATRDISldsELHDLRLNLEAKEQELNQSISEKE 490
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIE----NRLDELSQELSDASRKIG---EIEKEIEQLEQEEEKLKERLEELE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  491 TLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEkkRVHQLEDDKMDITKELDVQKEKLIQSEVAL 570
Cdd:TIGR02169  744 EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  571 NDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQdsnsnfkdtlLKEREAEV 650
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR----------LGDLKKER 891

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1012519614  651 RNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQL--SLEKNTIVETLKMEKGEIEAEL 724
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDeeIPEEELSLEDVQAELQRVEEEI 967
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 212-852 1.85e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 1.85e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  212 KLQNIIKELKQN-RSQEIDDHQHEMSVLQNAHQQKLTEIsRRHREELSDYEERIEELEnllqqggsgvietdlSKIYEMQ 290
Cdd:COG1196    217 ELKEELKELEAElLLLKLRELEAELEELEAELEELEAEL-EELEAELAELEAELEELR---------------LELEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  291 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTM 370
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  371 TEKERILAQSASVEEvfRLQQALSDAENEIMRLssLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNE 450
Cdd:COG1196    361 AEAEEALLEAEAELA--EAEEELEELAEELLEA--LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  451 YEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELdrQNQEATKHMILIKDQLSKQQNEGDSIISK 530
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE--LAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  531 LKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENL----VDQLNKSQESNVSIQKENL 606
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratFLPLDKIRARAALAAALAR 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  607 ELKEHIRQNEEELSRIRNELMQslnqdsnsNFKDTLLkEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACE 686
Cdd:COG1196    595 GAIGAAVDLVASDLREADARYY--------VLGDTLL-GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  687 DVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELcwakKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKL 766
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEE----EEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  767 NQKKDMEIAELKKNIEQMDtdhketkdvlssSLEEQKQLTQLINKKeifIEKL--------------KERSSKLQEELDK 832
Cdd:COG1196    742 LEEEELLEEEALEELPEPP------------DLEELERELERLERE---IEALgpvnllaieeyeelEERYDFLSEQRED 806

                          650       660
                   ....*....|....*....|
gi 1012519614  833 YSQALRKneiLRQTIEEKDR 852
Cdd:COG1196    807 LEEARET---LEEAIEEIDR 823
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 907-1751 7.70e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 7.70e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  907 LEEEIKHHQKII-----EDQNQSKMQLLQSLQEQKKEMDEFRyqhEQMNATHTQL------FLEKDEEIKSLQKTIEQIK 975
Cdd:TIGR02168  218 LKAELRELELALlvlrlEELREELEELQEELKEAEEELEELT---AELQELEEKLeelrleVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  976 TQLHEERQDIQ-TDNSDIFQETKVQSLN--IENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDE 1052
Cdd:TIGR02168  295 NEISRLEQQKQiLRERLANLERQLEELEaqLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1053 VGKLTQIIQQKDLEIQALHARissTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMdiVAAKEAAL 1132
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQI---ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1133 IKLQDENKKLSTRFESSgqdmfRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDK 1212
Cdd:TIGR02168  450 EELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1213 LKQQVKKMEEWKQQVmttvqnmqheSAQLQEELhqlqaQVLVDSDNNSKLQvdytgLIQSYEQNETKLKNF-------GQ 1285
Cdd:TIGR02168  525 LSELISVDEGYEAAI----------EAALGGRL-----QAVVVENLNAAKK-----AIAFLKQNELGRVTFlpldsikGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1286 ELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSAslLTPQSAECLRASksevlsesselLQQELEELRKSLQEKdATIRTL 1365
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA--LSYLLGGVLVVD-----------DLDNALELAKKLRPG-YRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1366 QENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTN 1445
Cdd:TIGR02168  651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1446 LKERILILEMDIGKLkgenekivetyrgkETEYQALQETNMKfsmmLREKEFECHSMKEKALAFEQLLKEKEQGKTGELN 1525
Cdd:TIGR02168  731 LRKDLARLEAEVEQL--------------EERIAQLSKELTE----LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1526 QLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRnhllESEDSYTREALAAEDRE 1605
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS----EDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1606 AKLRKKVTVLEEKLvsssNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQE 1685
Cdd:TIGR02168  869 EELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1686 EKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEAN----AALDSASRLTEQLDVKEEQIEELKR 1751
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvnlAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 475-1252 9.12e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 9.12e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  475 LEAKEQELNQSISEKETliaEIEELDRQnqeatkhmiliKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITK 554
Cdd:TIGR02168  237 LREELEELQEELKEAEE---ELEELTAE-----------LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  555 ELDVQKEKL----IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR--NELMQ 628
Cdd:TIGR02168  303 QKQILRERLanleRQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEelEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  629 SLNQDSNsnfkdtLLKEREAEVRN-LKQNLSELEQLNENLKkvafdvKMENEKLVLACEDVRHQLEECLAGNNqlslEKN 707
Cdd:TIGR02168  383 TLRSKVA------QLELQIASLNNeIERLEARLERLEDRRE------RLQQEIEELLKKLEEAELKELQAELE----ELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  708 TIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHliklnQKKDMEIAELKKNIEQMDTD 787
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-----EGFSEGVKALLKNQSGLSGI 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  788 HketkDVLSSSLEEQKQLTQLINKkeifieKLKERSSKL----QEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNH 863
Cdd:TIGR02168  522 L----GVLSELISVDEGYEAAIEA------ALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  864 LQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLE--EEIKHHQKIIEDQ----------NQSKMQLLQS 931
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElaKKLRPGYRIVTLDgdlvrpggviTGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  932 LQEQKKEMDEFRYQHEQMnathTQLFLEKDEEIKSLQKTIEQIKTQLHEER---QDIQTDNSDIFQETKVQSLNIENGSE 1008
Cdd:TIGR02168  672 ILERRREIEELEEKIEEL----EEKIAELEKALAELRKELEELEEELEQLRkelEELSRQISALRKDLARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1009 KHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLsKDEVGKLTQIIQQKDLEIQALHARISSTS-HTQDVVYLQ 1087
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL-EAQIEQLKEELKALREALDELRAELTLLNeEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1088 QQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMdivAAKEAALIKLQDENKKLSTRFESSGQDM--FRETIQNLSRII 1165
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEI---EELEELIEELESELEALLNERASLEEALalLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1166 REKDIEIDALSQKCQTLlavlqtsstgNEAGGVNSNQFEELLQERDKLKQQVkkMEEWK---QQVMTTVQNMQHESAQLQ 1242
Cdd:TIGR02168  904 RELESKRSELRRELEEL----------REKLAQLELRLEGLEVRIDNLQERL--SEEYSltlEEAEALENKIEDDEEEAR 971

                          810
                   ....*....|
gi 1012519614 1243 EELHQLQAQV 1252
Cdd:TIGR02168  972 RRLKRLENKI 981
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 306-626 1.06e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  306 KMEQLEDKIKDINKKLSSAENDRDILRREQEQLnvEKRQIMEEcenlKLECSKLQPSAVKQSDTMTEKERILAQSASVEE 385
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKA--ERYQALLK----EKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  386 VF---------------RLQQALSDAENEIMRLSSlNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNE 450
Cdd:TIGR02169  252 ELeklteeiselekrleEIEQLLEELNKKIKDLGE-EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  451 YEVIKSTATrdiSLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISK 530
Cdd:TIGR02169  331 IDKLLAEIE---ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  531 LKQDLNDEKKRVHQLEDDKMDITkeldVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKsqesnvsIQKENLELKE 610
Cdd:TIGR02169  408 LDRLQEELQRLSEELADLNAAIA----GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK-------YEQELYDLKE 476

                          330
                   ....*....|....*.
gi 1012519614  611 HIRQNEEELSRIRNEL 626
Cdd:TIGR02169  477 EYDRVEKELSKLQREL 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 68-852 1.24e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   68 ERLKKLCTDLEEKHEASeiqIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLKLQSAaqsvpsgagvpattasssfay 147
Cdd:TIGR02168  213 ERYKELKAELRELELAL---LVLRLEELREELEELQEELKEAEEELEELTAELQELEEK--------------------- 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  148 gISHHPSAFHDDDMDFGDIissQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQE 227
Cdd:TIGR02168  269 -LEELRLEVSELEEEIEEL---QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  228 iddhqhEMSVLQNAHQQKLTEISRRhREELSDYEERIEELENLLQQGGSGVIETdLSKIYEMQKTIQVLQIEKVESTKKM 307
Cdd:TIGR02168  345 ------KLEELKEELESLEAELEEL-EAELEELESRLEELEEQLETLRSKVAQL-ELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  308 EQLEDKIKDINKKLSsaENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSAS-VEEV 386
Cdd:TIGR02168  417 ERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArLDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  387 FRLQQALSDAENEIMRLssLNQDNSLAEDNLKLKMRIEVLEK-EKSLLSQEKEELQMSLLKLNNEYEVIKSTATR----- 460
Cdd:TIGR02168  495 ERLQENLEGFSEGVKAL--LKNQSGLSGILGVLSELISVDEGyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQnelgr 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  461 ------DISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEE------------------LDRQNQEATKHMILIKD- 515
Cdd:TIGR02168  573 vtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddldnaLELAKKLRPGYRIVTLDg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  516 -------------------QLSKQQN--EGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLH 574
Cdd:TIGR02168  653 dlvrpggvitggsaktnssILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  575 LTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRI---RNELMQSLNQDSNSNFKDTL-LKEREAEV 650
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAeaeIEELEAQIEQLKEELKALREaLDELRAEL 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  651 RNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKmEKGEIEAELCWAKKR 730
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE-ALLNERASLEEALAL 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  731 LLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKD---MEIAELKKNIEQ-----MDTDHKETKDVLSSSLEEQ 802
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEgleVRIDNLQERLSEeysltLEEAEALENKIEDDEEEAR 971

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  803 KQLTQLINKKEIF----------IEKLKERSSKLQEELDKYSQALRKneiLRQTIEEKDR 852
Cdd:TIGR02168  972 RRLKRLENKIKELgpvnlaaieeYEELKERYDFLTAQKEDLTEAKET---LEEAIEEIDR 1028
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 195-645 2.98e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.43  E-value: 2.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  195 QTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNaHQQKLTEISRRHREELSDYEERIEELENLLQQG 274
Cdd:TIGR04523  226 QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSE-KQKELEQNNKKIKELEKQLNQLKSEISDLNNQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  275 GSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKL 354
Cdd:TIGR04523  305 EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQ 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  355 ECSKLQPSAVKQSDTMTEKERILAQSAsvEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKmrIEVLEKEKSLLS 434
Cdd:TIGR04523  385 EIKNLESQINDLESKIQNQEKLNQQKD--EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ--DSVKELIIKNLD 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  435 QEKEELQMSLLKLNNEYEVIKStatrdisldselhdlrlNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK 514
Cdd:TIGR04523  461 NTRESLETQLKVLSRSINKIKQ-----------------NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  515 ---DQLSKQQNEGDSIISKLKQDLNDEK----------------KRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHL 575
Cdd:TIGR04523  524 ekiEKLESEKKEKESKISDLEDELNKDDfelkkenlekeideknKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK 603

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  576 TKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKE 645
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKT 673
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
212-829 1.95e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 1.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  212 KLQNIIKELKQNRSQEIDDHQHEMSV--LQNAHQQKLTEISRRHREELSDYEERIEELENLlqqggsgviETDLSKIYEM 289
Cdd:PRK03918   166 NLGEVIKEIKRRIERLEKFIKRTENIeeLIKEKEKELEEVLREINEISSELPELREELEKL---------EKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  290 QKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSsaendrdilrreqeqlnvEKRQIMEECENLKLECSKLQPSAVKQSDT 369
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIE------------------ELKKEIEELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 MTEKERILAQSASVEEvfRLQQALSDAENEIMRLSSLNQDNSLAEdnlKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 449
Cdd:PRK03918   299 SEFYEEYLDELREIEK--RLSRLEEEINGIEERIKELEEKEERLE---ELKKKLKELEKRLEELEERHELYEEAKAKKEE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  450 EYEVIKSTATRDIS-LDSELHDL---RLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGd 525
Cdd:PRK03918   374 LERLKKRLTGLTPEkLEKELEELekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKE- 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  526 sIISKLKQDLNDEKKRVHQLEDDKMDITKELdVQKEKLIQSEVALNDLHltkqKLEDKVENLVDQLNKSQESNVSIQKEN 605
Cdd:PRK03918   453 -LLEEYTAELKRIEKELKEIEEKERKLRKEL-RELEKVLKKESELIKLK----ELAEQLKELEEKLKKYNLEELEKKAEE 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  606 LE-LKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSEL-----EQLNENLKKVAfdvKMENE 679
Cdd:PRK03918   527 YEkLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesvEELEERLKELE---PFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  680 KLVLacEDVRHQLEECLagnNQLSLEKNTIVETLKmEKGEIEAELCWAKKRLLEEANKYEKtiEELSNARNLNTSalqLE 759
Cdd:PRK03918   604 YLEL--KDAEKELEREE---KELKKLEEELDKAFE-ELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLE---LS 672

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614  760 HEHLIKLNQKKDME--IAELKKNIEQMdtdhKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEE 829
Cdd:PRK03918   673 RELAGLRAELEELEkrREEIKKTLEKL----KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 241-980 2.43e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 2.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  241 AHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKK 320
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  321 LSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAvkQSDTMTEKERILAQSASVEEVFRLQQALSDAENEI 400
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAEL--EEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  401 MRLSSLNQdnSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEyevIKSTATRDISLDSELHDLRLNLEAKEQ 480
Cdd:TIGR02169  409 DRLQEELQ--RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK---LEQLAADLSKYEQELYDLKEEYDRVEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  481 ELNQSISEKETLIAEIEELDRQNQEATKHMILIKD----------QLSKQQNE---------GDSIISKLKQDLNDEKKR 541
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAsiqgvhgtvaQLGSVGERyataievaaGNRLNNVVVEDDAVAKEA 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  542 VHQLEDDK------MDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLV--------------------------- 588
Cdd:TIGR02169  564 IELLKRRKagratfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFkyvfgdtlvvedieaarrlmgkyrmvt 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  589 ---DQLNKS---------QESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLN-QDSNSNFKDTLLKEREAEVRNLKQ 655
Cdd:TIGR02169  644 legELFEKSgamtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRrIENRLDELSQELSDASRKIGEIEK 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  656 NLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEA 735
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKL 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  736 NKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEqmdtDHKETKDVLSSSLEEqkqLTQLINKKEIF 815
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEE---LEEELEELEAA 876

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  816 IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKdrslgsMKEENNHLQEELERLREEQSRTAPVADPKTLDsvtelaS 895
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQ------IEKKRKRLSELKAKLEALEEELSEIEDPKGED------E 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  896 EVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMnathtqlflekDEEIKSLQKTIEQIK 975
Cdd:TIGR02169  945 EIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKL-----------EEERKAILERIEEYE 1013


                   ....*
gi 1012519614  976 TQLHE 980
Cdd:TIGR02169 1014 KKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 372-974 2.50e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 2.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  372 EKERILAQSASVEEVFRLQQALSDAENEImrlsslnqdNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEY 451
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAEL---------EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  452 EVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISE----KETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEgdsi 527
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAEleeeLEELEEELEELEEELEEAEEELEEAEAELAEAEEA---- 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  528 ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLE 607
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  608 LKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNE-NLKKVAFDVKMENEKLVLACE 686
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  687 DVRHQLEECL---AGNNQLSLEKNTIVETLKMEKGEIEaelcWAKKRLLEEANKYEKT-IEELSNARNLNTSALQLEHEH 762
Cdd:COG1196    527 AVLIGVEAAYeaaLEAALAAALQNIVVEDDEVAAAAIE----YLKAAKAGRATFLPLDkIRARAALAAALARGAIGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  763 LIKLNQKKDMEIAELKKNI---EQMDTDHKETKDVLSSSLEEQKQLTQLinKKEIFIEKLKERSSKLQEELDKYSQALRK 839
Cdd:COG1196    603 LVASDLREADARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTL--EGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  840 NEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIE 919
Cdd:COG1196    681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1012519614  920 DQNQSKmQLLQSLQEQKKEM--------DEFRYQHEQMNATHTQLfleKD--EEIKSLQKTIEQI 974
Cdd:COG1196    761 DLEELE-RELERLEREIEALgpvnllaiEEYEELEERYDFLSEQR---EDleEARETLEEAIEEI 821
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 610-1435 3.33e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 3.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  610 EHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLS--ELEQLNENLKKVAFDVKMENEKlvlaCED 687
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLvlRLEELREELEELQEELKEAEEE----LEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  688 VRHQLEECLAGNNQLSLEKNTivetLKMEKGEIEAELcwakKRLLEEANKYEKTIEELSNAR-NLNTSALQLEhEHLIKL 766
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSE----LEEEIEELQKEL----YALANEISRLEQQKQILRERLaNLERQLEELE-AQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  767 NQKKDM---EIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALrknEIL 843
Cdd:TIGR02168  329 ESKLDElaeELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI---ERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  844 RQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDsvtELASEVSQLNTIKEHLEEEIKHHQKIIeDQNQ 923
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQAL-DAAE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  924 SKMQLLQSLQEQKKEMDEfryQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQ----------LHEERQDIQTDNSDIF 993
Cdd:TIGR02168  482 RELAQLQARLDSLERLQE---NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  994 QETkVQSLniengsEKHDLSKAeTERLVKGIKERELEIKLLNEKN---------ISLTKQIDQLSKDEVGKLTQIIQQKD 1064
Cdd:TIGR02168  559 KKA-IAFL------KQNELGRV-TFLPLDSIKGTEIQGNDREILKniegflgvaKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1065 LEiQALHARiSSTSHTQDVVYLQQQL----QAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENK 1140
Cdd:TIGR02168  631 LD-NALELA-KKLRPGYRIVTLDGDLvrpgGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1141 KLSTRFESsgqdmFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTsstgneaggvNSNQFEELLQERDKLKQQVKKM 1220
Cdd:TIGR02168  709 ELEEELEQ-----LRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----------LSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1221 EEWKQQVMTtvqnmqhESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNT 1300
Cdd:TIGR02168  774 EEELAEAEA-------EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1301 KDLLLGKLDIISPQLSSASLLTPQSAECL------RASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSD 1374
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELeallneRASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1012519614 1375 SIAATSELERKEHEQtdseIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNE 1435
Cdd:TIGR02168  927 LELRLEGLEVRIDNL----QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 254-1001 7.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  254 REELSDYE--ERIEELENLLQQggsgvIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDI- 330
Cdd:TIGR02169  217 LKEKREYEgyELLKEKEALERQ-----KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLr 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  331 LRREQEQLNVEKRQIMEECENLKLEcskLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRlsslnqdn 410
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERE---LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA-------- 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  411 SLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDIS----LDSELHDLRLNLEAKEQELNQSI 486
Cdd:TIGR02169  361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEelqrLSEELADLNAAIAGIEAKINELE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  487 SEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSI---ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKL 563
Cdd:TIGR02169  441 EEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQRELAEAEAQARASEERVRGGRAVEEVLKASI 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  564 IQSEVALNDLHLTKQKLEDKVEN-LVDQLNKSQESNVSIQKENLE-LKEH------------IRQNEEELSRIRNE---- 625
Cdd:TIGR02169  521 QGVHGTVAQLGSVGERYATAIEVaAGNRLNNVVVEDDAVAKEAIElLKRRkagratflplnkMRDERRDLSILSEDgvig 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  626 -LMQSLNQDSNSN------FKDTLLKEREAEVRNLkqnlseleqlnenLKKVAFdVKMENEKLVLACEDVRHQLEECLAG 698
Cdd:TIGR02169  601 fAVDLVEFDPKYEpafkyvFGDTLVVEDIEAARRL-------------MGKYRM-VTLEGELFEKSGAMTGGSRAPRGGI 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  699 NNQLSLEKNtiVETLKMEKGEIEAELcwakKRLLEEANKYEKTIEELSNARnlntSALQLEHEHLIKLNQKKDMEIAELK 778
Cdd:TIGR02169  667 LFSRSEPAE--LQRLRERLEGLKREL----SSLQSELRRIENRLDELSQEL----SDASRKIGEIEKEIEQLEQEEEKLK 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  779 KNIEQMDTDHKETKDVLSSSLEEQKQLtqlinkkEIFIEKLKERSSKLQEELDKYSQALRkneilRQTIEEKDRSLGSMK 858
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVKSELKEL-------EARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLE 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  859 EENNHLQEelerlreeqsrtapvadpktldSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKE 938
Cdd:TIGR02169  805 EEVSRIEA----------------------RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  939 MDEFRYQHEQMNATHTQLflekDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSL 1001
Cdd:TIGR02169  863 KEELEEELEELEAALRDL----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE 921
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 551-1098 1.65e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  551 DITKELDVQKEKL-IQSEVA---------------------LNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLEL 608
Cdd:COG1196    193 DILGELERQLEPLeRQAEKAeryrelkeelkeleaellllkLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  609 KEHIRQNEEELSRIRNELMQSLNQdsnsnfKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDV 688
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAE------LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  689 RHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAElcwakKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQ 768
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-----EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  769 KKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIE 848
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  849 EKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDsvTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQL 928
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  929 LQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIE---QIKTQLHEERQDIQTDNSDIFQETKVQSLNIEN 1005
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1006 GSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEvgKLTQIIQQKDLEIQALHARISSTSHTQDVVY 1085
Cdd:COG1196    660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE--RELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570
                   ....*....|...
gi 1012519614 1086 LQQQLQAYAMERE 1098
Cdd:COG1196    738 LEELLEEEELLEE 750
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 212-1129 4.27e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.52  E-value: 4.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  212 KLQNIIKELKQNRSQEIDDHQHEMSVLQNaHQQKLTEI-----SRRHREELS-----DYEERIEELENLLQQggsgvIET 281
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKQ-YKEKACEIrdqitSKEAQLESSreivkSYENELDPLKNRLKE-----IEH 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  282 DLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDI---------------NKKLSSAENDRDILRREQEQLNVEKRQIM 346
Cdd:TIGR00606  260 NLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtdeqlndlyhnhQRTVREKERELVDCQRELEKLNKERRLLN 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  347 EECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQAlSDAENEIMRLSSL------------NQDNSLAE 414
Cdd:TIGR00606  340 QEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERG-PFSERQIKNFHTLvierqedeaktaAQLCADLQ 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  415 DNLKLKMR------------IEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRL-----NLEA 477
Cdd:TIGR00606  419 SKERLKQEqadeirdekkglGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKaeknsLTET 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  478 KEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK--DQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKE 555
Cdd:TIGR00606  499 LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTqmEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDW 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  556 LDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLnKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSN 635
Cdd:TIGR00606  579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNEL-ESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAM 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  636 SNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKM 715
Cdd:TIGR00606  658 LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQS 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  716 EKGEIEAELcwakKRLLEEANKYEKTIEELSNARNlntsalqlEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVl 795
Cdd:TIGR00606  738 IIDLKEKEI----PELRNKLQKVNRDIQRLKNDIE--------EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDV- 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  796 SSSLEEQKQLTQLINKKEIFIEKLKERSSKlQEELDKYSQalrKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQ 875
Cdd:TIGR00606  805 ERKIAQQAAKLQGSDLDRTVQQVNQEKQEK-QHELDTVVS---KIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNL 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  876 SRTAPVAdpktlDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEM--------DEFRYQHE 947
Cdd:TIGR00606  881 QRRQQFE-----EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAqdkvndikEKVKNIHG 955

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  948 QMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIfqetKVQSLNIENGSEKHDLSKAETERLVkgikeR 1027
Cdd:TIGR00606  956 YMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDM----RLMRQDIDTQKIQERWLQDNLTLRK-----R 1026

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1028 ELEIKLLNEKNISLTKQIDQLskdevgkltQIIQQKDlEIQALHARISSTSHTQDVVYLQQQlqayAMEREKVFAVLNEK 1107
Cdd:TIGR00606 1027 ENELKEVEEELKQHLKEMGQM---------QVLQMKQ-EHQKLEENIDLIKRNHVLALGRQK----GYEKEIKHFKKELR 1092

                          970       980
                   ....*....|....*....|..
gi 1012519614 1108 TRENSHLKTEYHKMMDIVAAKE 1129
Cdd:TIGR00606 1093 EPQFRDAEEKYREMMIVMRTTE 1114
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 283-653 4.73e-08

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 58.53  E-value: 4.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  283 LSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRrEQEQLNVEKRQIMEEcenlklecsklQPS 362
Cdd:PRK10929    64 LERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMSTDALEQEILQ-VSSQLLEKSRQAQQE-----------QDR 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  363 AVKQSDTMTEkeriLAQSASveEVFRlqqALSDAENEIMRLSSLNqdNSLAEDNLKLkmrievLEKEKSLLSQEKEELQM 442
Cdd:PRK10929   132 AREISDSLSQ----LPQQQT--EARR---QLNEIERRLQTLGTPN--TPLAQAQLTA------LQAESAALKALVDELEL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  443 SLLKLNNEYEVIKSTA----TRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAE--------IEELDRQNQE----- 505
Cdd:PRK10929   195 AQLSANNRQELARLRSelakKRSQQLDAYLQALRNQLNSQRQREAERALESTELLAEqsgdlpksIVAQFKINRElsqal 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  506 --ATKHMilikDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKM-------DITKELDVQKEKLIQSEVAlnDLHLT 576
Cdd:PRK10929   275 nqQAQRM----DLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNAlgealraQVARLPEMPKPQQLDTEMA--QLRVQ 348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  577 KQKLEDkvenlvdQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQD-------------SNSNFKDTLL 643
Cdd:PRK10929   349 RLRYED-------LLNKQPQLRQIRQADGQPLTAEQNRILDAQLRTQRELLNSLLSGgdtlileltklkvANSQLEDALK 421

                          410
                   ....*....|
gi 1012519614  644 KEREAEVRNL 653
Cdd:PRK10929   422 EVNEATHRYL 431
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 493-1416 5.00e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  493 IAEIEELDRQNQEATKHMilikDQLSKQQNEGDSIISKLKQdlndekkRVHQLEDDKMDITKELDVQKEKliqSEVALND 572
Cdd:TIGR02169  162 IAGVAEFDRKKEKALEEL----EEVEENIERLDLIIDEKRQ-------QLERLRREREKAERYQALLKEK---REYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  573 LHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIrNELMQSLNQDSNSNFKDTLLkEREAEVRN 652
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL-NKKIKDLGEEEQLRVKEKIG-ELEAEIAS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  653 LKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLE---KNTIVETLKMEKGEIEAELcwakK 729
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEyaeLKEELEDLRAELEEVDKEF----A 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  730 RLLEEANKYEKTIEELSNARNlntsALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLI 809
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREIN----ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  810 NKKEIFIEKLKERSSKLQEELDKYSQALRKNEilRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDS 889
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQ--RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  890 VTELASEVS---QLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLqSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKS 966
Cdd:TIGR02169  536 RYATAIEVAagnRLNNVVVEDDAVAKEAIELLKRRKAGRATFL-PLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEP 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  967 ----------LQKTIEQIKTQLHEERqdIQTDNSDIFQETKVQ---SLNIENGSEKHDLSKAETERLVKGIKERELEIKL 1033
Cdd:TIGR02169  615 afkyvfgdtlVVEDIEAARRLMGKYR--MVTLEGELFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1034 LNEKNISLTKQIDQLSkDEVGKLTQIIQQKDLEIQALharisstshtqdvvylQQQLQAYAMEREKVFAVLNEKTRENSH 1113
Cdd:TIGR02169  693 LQSELRRIENRLDELS-QELSDASRKIGEIEKEIEQL----------------EQEEEKLKERLEELEEDLSSLEQEIEN 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1114 LKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLqtsstgn 1193
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK------- 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1194 eaggvnsnqfEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSY 1273
Cdd:TIGR02169  829 ----------EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1274 EQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSAslltpqsaeclrasksevlsessellqqeleelrK 1353
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED----------------------------------E 944

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1012519614 1354 SLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIK 1416
Cdd:TIGR02169  945 EIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1126-1770 1.46e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 1.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1126 AAKEAALIKLQDENKKLSTRFESsgQDMFRETIQNLSRIIREKDIEIDAL---SQKCQTLLAVLQTS--STGNEAGGVNS 1200
Cdd:TIGR02168  225 LELALLVLRLEELREELEELQEE--LKEAEEELEELTAELQELEEKLEELrleVSELEEEIEELQKElyALANEISRLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1201 nQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKL 1280
Cdd:TIGR02168  303 -QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1281 KNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASlltpQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDA 1360
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQ----QEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1361 TIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSD-----QLLSSNENFTNK--- 1432
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilGVLSELISVDEGyea 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1433 --------------VNENELLRQAVTNLKE----RILILEMDI---GKLKGENEKIVETYRGKETEYQALQETNMKFSMM 1491
Cdd:TIGR02168  538 aieaalggrlqavvVENLNAAKKAIAFLKQnelgRVTFLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1492 LREKEFECHSMKEKALAFEQLLKEKEQG----KTGEL---------------NQLL---NAVKSMQEKTVVFQQERDQVM 1549
Cdd:TIGR02168  618 LSYLLGGVLVVDDLDNALELAKKLRPGYrivtLDGDLvrpggvitggsaktnSSILerrREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1550 LALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEdsytREALAAEDREAKLRKKVTVLEEKLVSSSNAMENA 1629
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1630 S---HQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQeEKAMYSAELEKQKQLIAEWKK 1706
Cdd:TIGR02168  774 EeelAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER-RIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1012519614 1707 NAENLEGKVISLQECLDEANAALDSasrLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSL 1770
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEA---LLNERASLEEALALLRSELEELSEELRELESKRSEL 913
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1352-1680 1.63e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1352 RKSLQEKDATIRTLQENNHRLSDSIAATSELERKEhEQTDSEIKQLKEKQDV----LQKLLKEKDLLIKAKSdQLLSSNE 1427
Cdd:pfam15921  478 RKVVEELTAKKMTLESSERTVSDLTASLQEKERAI-EATNAEITKLRSRVDLklqeLQHLKNEGDHLRNVQT-ECEALKL 555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1428 NFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKE-----FECHSM 1502
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsdLELEKV 635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1503 KEKALAFEQLLKEKEQGKtgELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMEntaLQNEVQRLRDKEFRSNQELER 1582
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQ--ERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEE---METTTNKLKMQLKSAQSELEQ 710

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1583 LRNHL--LESEDSYT-REALAAEDREAKLRKKVTVLEEKLVSSSNAMENAS---HQASVQVESLQEQLNVVSKQRDETAL 1656
Cdd:pfam15921  711 TRNTLksMEGSDGHAmKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANkekHFLKEEKNKLSQELSTVATEKNKMAG 790

                          330       340
                   ....*....|....*....|....
gi 1012519614 1657 QLSVSQEQVKQYALSLANLQMVLE 1680
Cdd:pfam15921  791 ELEVLRSQERRLKEKVANMEVALD 814
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 640-1314 1.86e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  640 DTLLKEREAEVRNLKQNLSELEQLNE-----------NLKKVAFDVKMENEKLV-------LACEDVRHQLEECLagnNQ 701
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEkqkfylrqsviDLQTKLQEMQMERDAMAdirrresQSQEDLRNQLQNTV---HE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  702 LSLEKNTIVETLKMEKGEIEA--ELCWAKKRLLEEANKYEKTIEELSNAR-----NLNTSALQLEHEHLIKLNQKKDMEI 774
Cdd:pfam15921  154 LEAAKCLKEDMLEDSNTQIEQlrKMMLSHEGVLQEIRSILVDFEEASGKKiyehdSMSTMHFRSLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  775 AELKKNI----EQMDTDHKETKDVLSSSLEE-QKQLTQLINKKEIFIEKLKERSSKLQEELDKYS--------QALRKNE 841
Cdd:pfam15921  234 SYLKGRIfpveDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQsqleiiqeQARNQNS 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  842 ILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKtldsVTELASEVSQLNTIKEHLEEEIkhhQKIIEDQ 921
Cdd:pfam15921  314 MYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSE----LTEARTERDQFSQESGNLDDQL---QKLLADL 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  922 NQSKMQLLQSLQEQKKEMDefRYQHEQMNATHTQLFL-EKDEEIKSLQKTIEQIKT----QLHEERQDIQTDNSDIfqeT 996
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWD--RDTGNSITIDHLRRELdDRNMEVQRLEALLKAMKSecqgQMERQMAAIQGKNESL---E 461

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  997 KVQSLNIENGSEKHDLSKAETERLVKGIKERELEiKLLNEKNISLTKQiDQLSKDEVGKLTQIIQQKDLEIQALHARISS 1076
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSE-RTVSDLTASLQEK-ERAIEATNAEITKLRSRVDLKLQELQHLKNE 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1077 TSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIK--------------LQDENKKL 1142
Cdd:pfam15921  540 GDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKeindrrlelqefkiLKDKKDAK 619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1143 STRFESSGQDMFRETIQNLS------RIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVN-SNQFEELLQERDKLKQ 1215
Cdd:pfam15921  620 IRELEARVSDLELEKVKLVNagserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNfRNKSEEMETTTNKLKM 699

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1216 QVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTgLIQSYEQNETKLKNF-GQELAQVQHSI 1294
Cdd:pfam15921  700 QLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ-FLEEAMTNANKEKHFlKEEKNKLSQEL 778

                          730       740
                   ....*....|....*....|
gi 1012519614 1295 GQLCNTKDLLLGKLDIISPQ 1314
Cdd:pfam15921  779 STVATEKNKMAGELEVLRSQ 798
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 424-1228 2.29e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 2.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  424 EVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQN 503
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  504 QEATKHMILIKDQLSKQQNEgdsiISKLKQDLNDEKKRVHQLEDDKMD-ITKELDVQKEKLIQSEVALNDLHLTKQKLED 582
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEE----KLAQVLKENKEEEKEKKLQEEELKlLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  583 KVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQ 662
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  663 LNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTI 742
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  743 EELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELK--KNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLK 820
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKdgVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  821 ERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEV--- 897
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKesa 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  898 ----SQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQ 973
Cdd:pfam02463  642 kakeSGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  974 IKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEV 1053
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1054 GKLTQIIQQKDLEI----------QALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKM-- 1121
Cdd:pfam02463  802 ELRALEEELKEEAElleeeqllieQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELee 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1122 MDIVAAKEAALIKLQDENKKLSTRFESSGQDMFREtIQNLSRIIREKDIEIDALSQKcqtllavlqTSSTGNEAGGVNSN 1201
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKE-NEIEERIKEEAEILLKYEEEP---------EELLLEEADEKEKE 951

                          810       820
                   ....*....|....*....|....*..
gi 1012519614 1202 QFEELLQERDKLKQQVKKMEEWKQQVM 1228
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAKEELGKVNLM 978
PTZ00121 PTZ00121
MAEBL; Provisional
 643-1134 2.35e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 2.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  643 LKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVR--HQLEECLAGNNQLSLEKNTIVETLKMEKGEI 720
Cdd:PTZ00121  1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKkaDELKKAAAAKKKADEAKKKAEEKKKADEAKK 1438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  721 EAElcwaKKRLLEEAnkyEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMdtdhKETKDVLSSSLE 800
Cdd:PTZ00121  1439 KAE----EAKKADEA---KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA----KKKADEAKKAAE 1507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  801 EQKQLTQLINKKEIF-IEKLKERSSKLQEELDKYSQALRKNEILRQTiEEKDRSLGSMKEENNHLQEELERLREEQSRTA 879
Cdd:PTZ00121  1508 AKKKADEAKKAEEAKkADEAKKAEEAKKADEAKKAEEKKKADELKKA-EELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  880 PVADPKTLDSVTELASEVSQLNT--IKEHLEEEIKHHQ-KIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQL 956
Cdd:PTZ00121  1587 KKAEEARIEEVMKLYEEEKKMKAeeAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  957 FLEKDEEikslQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNE 1036
Cdd:PTZ00121  1667 AKKAEED----KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1037 KNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENShLKT 1116
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGN-LVI 1821

                          490
                   ....*....|....*...
gi 1012519614 1117 EYHKMMDIVAAKEAALIK 1134
Cdd:PTZ00121  1822 NDSKEMEDSAIKEVADSK 1839
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 200-830 2.45e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.80  E-value: 2.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  200 QGTDNSDQSEICKLQNIIKELKQNRSQEIDdhqhemsvlqnahqqklteisrrhreELSDYEERIEELENllqqggsgvi 279
Cdd:TIGR04523   60 DKNLNKDEEKINNSNNKIKILEQQIKDLND--------------------------KLKKNKDKINKLNS---------- 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  280 etDLSKIYEMQKT-IQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILrreqEQLNVEKRQIMEECENLKLECSK 358
Cdd:TIGR04523  104 --DLSKINSEIKNdKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKEL----EKLNNKYNDLKKQKEELENELNL 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  359 LqpsavkqSDTMTEKERILAQSASveEVFRLQQALSDAENEImrlsslnqdnslaEDNLKLKMRIEVLEKEKSLLSQEKE 438
Cdd:TIGR04523  178 L-------EKEKLNIQKNIDKIKN--KLLKLELLLSNLKKKI-------------QKNKSLESQISELKKQNNQLKDNIE 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  439 ELQMSLLKLNNEyevIKSTATRDISLDSELHDLRLNLEAKEQELNQS---ISEKETLIAEI--EELDRQNQEATKHMILI 513
Cdd:TIGR04523  236 KKQQEINEKTTE---ISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNnkkIKELEKQLNQLksEISDLNNQKEQDWNKEL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  514 KDQLSKQQN----------EGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDK 583
Cdd:TIGR04523  313 KSELKNQEKkleeiqnqisQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  584 VENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLL----KEREAEVRNLKQNLSE 659
Cdd:TIGR04523  393 INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKeliiKNLDNTRESLETQLKV 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  660 LEQLNENLKKVAFDVKME---NEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLE-EA 735
Cdd:TIGR04523  473 LSRSINKIKQNLEQKQKElksKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKdDF 552

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  736 NKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMdTDHKETKDVLSSSLEEQKQLTQLINKK-EI 814
Cdd:TIGR04523  553 ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDL-IKEIEEKEKKISSLEKELEKAKKENEKlSS 631

                          650
                   ....*....|....*.
gi 1012519614  815 FIEKLKERSSKLQEEL 830
Cdd:TIGR04523  632 IIKNIKSKKNKLKQEV 647
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 285-508 3.45e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  285 KIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAV 364
Cdd:COG4942     35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALY 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  365 KQSDtmTEKERILAQSASVEEVFRLQQALSDAeneimrlssLNQDNSLAEDnlkLKMRIEVLEKEKSLLSQEKEELQMSL 444
Cdd:COG4942    115 RLGR--QPPLALLLSPEDFLDAVRRLQYLKYL---------APARREQAEE---LRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1012519614  445 LKLNNEYEVIKSTATRdisLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATK 508
Cdd:COG4942    181 AELEEERAALEALKAE---RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK01156 PRK01156
chromosome segregation protein; Provisional
 306-849 3.70e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 55.29  E-value: 3.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  306 KMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQpsavKQSDTMTEKErilaqsasvEE 385
Cdd:PRK01156   191 KLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELS----SLEDMKNRYE---------SE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  386 VFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLE--KEKSLLSQEKEELQMSLLKLNNEYEVIKSTAtrDIS 463
Cdd:PRK01156   258 IKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDyfKYKNDIENKKQILSNIDAEINKYHAIIKKLS--VLQ 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  464 LDselHDLRLNLEAKEQELNQSISEKET-------LIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLN 536
Cdd:PRK01156   336 KD---YNDYIKKKSRYDDLNNQILELEGyemdynsYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELN 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  537 DEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDL-----------HLTKQKLEDKVENLVDQLNKSQESNVSIQKEN 605
Cdd:PRK01156   413 EINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgtTLGEEKSNHIINHYNEKKSRLEEKIREIEIEV 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  606 LELKEHIRQNEEELSRIRNELMQSLNQDSNsnfkdtLLKEREAEVRNLKQNLSELEQlnENLKKVAFDVKMENEKLvlac 685
Cdd:PRK01156   493 KDIDEKIVDLKKRKEYLESEEINKSINEYN------KIESARADLEDIKIKINELKD--KHDKYEEIKNRYKSLKL---- 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  686 EDVRHQLEECLAGNNQLSlekNTIVETLKMEKGEIEAELCWAKKRLLEeankyekTIEELSNARNLNTSALQLEHEHLIK 765
Cdd:PRK01156   561 EDLDSKRTSWLNALAVIS---LIDIETNRSRSNEIKKQLNDLESRLQE-------IEIGFPDDKSYIDKSIREIENEANN 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  766 LNQKKDmEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQ 845
Cdd:PRK01156   631 LNNKYN-EIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRT 709


                   ....
gi 1012519614  846 TIEE 849
Cdd:PRK01156   710 RINE 713
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
388-860 5.49e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 5.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  388 RLQQALSDAENEIMRLSSLNQDNSLAEDNLK-LKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDS 466
Cdd:PRK03918   166 NLGEVIKEIKRRIERLEKFIKRTENIEELIKeKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  467 ELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQE-------ATKHMILIK--DQLSKQQNEGDSIISKLKQDLND 537
Cdd:PRK03918   246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkelkekAEEYIKLSEfyEEYLDELREIEKRLSRLEEEING 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  538 EKKRVHQLEDDKMDItKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLvdQLNKSQESNVSIQKENLELKEHIRQNEE 617
Cdd:PRK03918   326 IEERIKELEEKEERL-EELKKKLKELEKRLEELEERHELYEEAKAKKEEL--ERLKKRLTGLTPEKLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  618 -------------ELSRIRNELMQSLNQ-------------DSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVA 671
Cdd:PRK03918   403 ieeeiskitarigELKKEIKELKKAIEElkkakgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  672 FDVKME--NEKLVLACEDVRHQL---EECLAGNNQLSLEKNT-IVETLKMEKGEIEAELCWAKKRlLEEANKYEKTIEEL 745
Cdd:PRK03918   483 RELEKVlkKESELIKLKELAEQLkelEEKLKKYNLEELEKKAeEYEKLKEKLIKLKGEIKSLKKE-LEKLEELKKKLAEL 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  746 SNA-RNLNTSALQLEHEhlikLNQKKDMEIAELKKNIEQMDTDHKE------TKDVLSSSLEEQKQLTQLINKKEIFIEK 818
Cdd:PRK03918   562 EKKlDELEEELAELLKE----LEELGFESVEELEERLKELEPFYNEylelkdAEKELEREEKELKKLEEELDKAFEELAE 637

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1012519614  819 LKERSSKLQEELD----KYSQalRKNEILRQTIEEKDRSLGSMKEE 860
Cdd:PRK03918   638 TEKRLEELRKELEelekKYSE--EEYEELREEYLELSRELAGLRAE 681
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 165-1083 6.07e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 6.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  165 DIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDdhqhemsvlqnahqq 244
Cdd:TIGR01612  573 DSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNISDKNEYIKKAIDLKKIIENNNAYID--------------- 637

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  245 kltEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIY-EMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSS 323
Cdd:TIGR01612  638 ---ELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYnELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  324 AENdrdilrreqeqlnvekrqimeecENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEevfrLQQALSDAENEIMRL 403
Cdd:TIGR01612  715 MET-----------------------ATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD----LNKILEDFKNKEKEL 767

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  404 SSLNQDNSLAEDNL-KLKMRIEVLE---KEKSLLSQEKEELQMSLLKLNNEYevikstaTRDISLdselhdlrlnleaKE 479
Cdd:TIGR01612  768 SNKINDYAKEKDELnKYKSKISEIKnhyNDQINIDNIKDEDAKQNYDKSKEY-------IKTISI-------------KE 827

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  480 QELNQSISEKETLIAEI-EELDRQNQEATKHmiliKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLE-DDKMDITKELD 557
Cdd:TIGR01612  828 DEIFKIINEMKFMKDDFlNKVDKFINFENNC----KEKIDSEHEQFAELTNKIKAEISDDKLNDYEKKfNDSKSLINEIN 903

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  558 VQKEKLIQSEVALNDLH-------LTKQKLEdKVENLVDQLNKSQESNVSIQKE-NLELKEHIRQNEEELSRIRNELMQS 629
Cdd:TIGR01612  904 KSIEEEYQNINTLKKVDeyikiceNTKESIE-KFHNKQNILKEILNKNIDTIKEsNLIEKSYKDKFDNTLIDKINELDKA 982

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  630 lnqdsnsnFKDTLLKEREAEVRNLKQNLSEL-EQLNENLKKVAFDVKMENEKlvlACEDVRHQLEECLAGNNQLSLEKNT 708
Cdd:TIGR01612  983 --------FKDASLNDYEAKNNELIKYFNDLkANLGKNKENMLYHQFDEKEK---ATNDIEQKIEDANKNIPNIEIAIHT 1051

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  709 IVETLKME-KGEIEAELCWAKKRLLEEANkyektieelSNARNLNTSALQLEHEHLIKL----NQKKDMEIAELKKNIEQ 783
Cdd:TIGR01612 1052 SIYNIIDEiEKEIGKNIELLNKEILEEAE---------INITNFNEIKEKLKHYNFDDFgkeeNIKYADEINKIKDDIKN 1122

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  784 MdtDHKETKDVlsssleeqKQLTQLINKKEIFIEKLKERSSKLQEELDK--YSQALRKNEILRQTIEEKDRSLGSMKEEN 861
Cdd:TIGR01612 1123 L--DQKIDHHI--------KALEEIKKKSENYIDEIKAQINDLEDVADKaiSNDDPEEIEKKIENIVTKIDKKKNIYDEI 1192

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  862 NHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIED------QNQSKMQLLQSLQEQ 935
Cdd:TIGR01612 1193 KKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDldeikeKSPEIENEMGIEMDI 1272

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  936 KKEMDEFRYQHEQMNATHTqLFLEKDEEI-----KSLQKT--------IEQIKTQLHEERQDIQTDNSDIFQETKvQSLN 1002
Cdd:TIGR01612 1273 KAEMETFNISHDDDKDHHI-ISKKHDENIsdireKSLKIIedfseesdINDIKKELQKNLLDAQKHNSDINLYLN-EIAN 1350

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1003 IENgsekhDLSKAETERLVKGIKERELEIKLLNeKNISltkqiDQLSKDEvgKLTQIIQQkDLEIQALHARISSTSHTQD 1082
Cdd:TIGR01612 1351 IYN-----ILKLNKIKKIIDEVKEYTKEIEENN-KNIK-----DELDKSE--KLIKKIKD-DINLEECKSKIESTLDDKD 1416


                   .
gi 1012519614 1083 V 1083
Cdd:TIGR01612 1417 I 1417
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1502-1764 1.45e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1502 MKEKALAFEQLLKEKEQgKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1581
Cdd:COG1196    248 LEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1582 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVS 1661
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1662 QEQVKQYALSLANLQMVLEHFQQEEKAmySAELEKQKQLIAEWKKNAENLEGKVISLQECLDEanaALDSASRLTEQLDV 1741
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAEL--EEEEEEEEEALEEAAEEEAELEEEEEALLELLAE---LLEEAALLEAALAE 481

                          250       260
                   ....*....|....*....|...
gi 1012519614 1742 KEEQIEELKRQNELRQEMLDDVQ 1764
Cdd:COG1196    482 LLEELAEAAARLLLLLEAEADYE 504
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 504-1144 2.12e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  504 QEATKHMILIKDQLSKQQNEgdsiISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDK 583
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNKEKE----LKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  584 VENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFK----DTLLKEREAEVRNLKQNLSE 659
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQkeelENELNLLEKEKLNIQKNIDK 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  660 LEQLNENLKKVAFDVKMENEKLVLacedVRHQLEECLAGNNQLslekNTIVETLKMEKGEIEAELCWAKKRLLEEANKYE 739
Cdd:TIGR04523  192 IKNKLLKLELLLSNLKKKIQKNKS----LESQISELKKQNNQL----KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  740 KTIEELSNARNLNTSALQLEHEHLIKLNQKKdMEIAELKKNIEQmdTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKL 819
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELEKQLNQLK-SEISDLNNQKEQ--DWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  820 KERSSKLQEELDKYSQalrKNEILRQTIEEKDRSLGSMKEENNhlqeelerlreeqsrtapvadpKTLDSVTELASEVSQ 899
Cdd:TIGR04523  341 NEQISQLKKELTNSES---ENSEKQRELEEKQNEIEKLKKENQ----------------------SYKQEIKNLESQIND 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  900 LNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTqlflEKDEEIKSLQKTIEQIKTQLH 979
Cdd:TIGR04523  396 LESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDS----VKELIIKNLDNTRESLETQLK 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  980 EERQDIQTDNSDIFQETKvqslNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKdEVGKLTQI 1059
Cdd:TIGR04523  472 VLSRSINKIKQNLEQKQK----ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES-KISDLEDE 546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1060 IQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDEN 1139
Cdd:TIGR04523  547 LNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626


                   ....*
gi 1012519614 1140 KKLST 1144
Cdd:TIGR04523  627 EKLSS 631
PTZ00121 PTZ00121
MAEBL; Provisional
 239-1055 2.98e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  239 QNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVietDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIK-DI 317
Cdd:PTZ00121  1146 RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE---EVRKAEELRKAEDARKAEAARKAEEERKAEEARKaED 1222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  318 NKKLSSAENDRDILRREQEQLNVEKRQIMEECEnlKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQAlsDAE 397
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIR--KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA--KKA 1298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  398 NEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQmsllklnNEYEVIKSTAtrdisldselhdlrlnlEA 477
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK-------KAAEAAKAEA-----------------EA 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  478 KEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK--DQLSKQQNEGDSIISKLKQDlNDEKKRVHQLEDDKMDITKE 555
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKkaDEAKKKAEEDKKKADELKKA-AAAKKKADEAKKKAEEKKKA 1433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  556 LDVQKEKliqSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQK-ENLELKEHIRQNEEELSRIRNELMQSLNQDS 634
Cdd:PTZ00121  1434 DEAKKKA---EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKaEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  635 NSN-FKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEklVLACEDVRhQLEECLAGNNQLSLEKNTIVETL 713
Cdd:PTZ00121  1511 KADeAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEE--LKKAEEKK-KAEEAKKAEEDKNMALRKAEEAK 1587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  714 KMEKGEIEAELCW---AKKRLLEEANKYEKT---IEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTD 787
Cdd:PTZ00121  1588 KAEEARIEEVMKLyeeEKKMKAEEAKKAEEAkikAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA 1667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  788 HKETKDvlSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEE 867
Cdd:PTZ00121  1668 KKAEED--KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  868 LERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHE 947
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSK 1825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  948 QMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHdlskaETERLVKGIKER 1027
Cdd:PTZ00121  1826 EMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD-----EIEKIDKDDIER 1900

                          810       820
                   ....*....|....*....|....*...
gi 1012519614 1028 ELEIKLLNEKNISLTKqiDQLSKDEVGK 1055
Cdd:PTZ00121  1901 EIPNNNMAGKNNDIID--DKLDKDEYIK 1926
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 610-1284 9.68e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 9.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  610 EHIRQNEEELSRIRNELMQSLnqdsnsnfkDTLlkEREAEV----RNLKQNLSELEQlnenlkkvafdvkmenEKLVLAC 685
Cdd:COG1196    182 EATEENLERLEDILGELERQL---------EPL--ERQAEKaeryRELKEELKELEA----------------ELLLLKL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  686 EDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAelcwAKKRLLEEANKYEKTIEELSNARNlNTSALQLEHEHLIK 765
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEE----LRLELEELELELEEAQAEEYELLA-ELARLEQDIARLEE 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  766 LNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDkysqalrknEILRQ 845
Cdd:COG1196    310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA---------EAEEE 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  846 TIEEKDRSLGSMKEENNHLQEELERLREEQSRtapvadpktLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSK 925
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEAL---------LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  926 MQLLQSLQEQKKEMDEFRYQHEQMNATHTQLfLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIEN 1005
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAEL-LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1006 GSEKHDLSKAETERLVkgikereLEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVY 1085
Cdd:COG1196    531 GVEAAYEAALEAALAA-------ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1086 LQQQLQAYAMEREKVFAVLNEKTRENSHLKTeyhkmmdivAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRII 1165
Cdd:COG1196    604 VASDLREADARYYVLGDTLLGRTLVAARLEA---------ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1166 REKDIEIDALSQKCQTLLAVLQTsstgneaggvnsnQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEEL 1245
Cdd:COG1196    675 LEAEAELEELAERLAEEELELEE-------------ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1012519614 1246 HQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFG 1284
Cdd:COG1196    742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1542-1777 9.74e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 9.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1542 QQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESE---DSYTREALAAEDREAKLRKKVTVLEEK 1618
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArriRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1619 LVSssnamenashqasvQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYS--AELEK 1696
Cdd:COG4942     99 LEA--------------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAdlAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1697 QKQLIAEWKKNAENLEGKVISLQECLDEANAALDSA-SRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSE 1775
Cdd:COG4942    165 LRAELEAERAELEALLAELEEERAALEALKAERQKLlARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244


                   ..
gi 1012519614 1776 GK 1777
Cdd:COG4942    245 AA 246
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1362-1770 1.19e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1362 IRTLQENNHRLSDSIAATSELERKEHEQTDS---EIKQLKEKQDVLQKLLKEKDLLIKAKSDqLLSSNENFTNKVNENEL 1438
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKEleeVLREINEISSELPELREELEKLEKEVKE-LEELKEEIEELEKELES 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1439 LRQAVTNLKERILILEMDIGKLKG------ENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQL 1512
Cdd:PRK03918   250 LEGSKRKLEEKIRELEERIEELKKeieeleEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1513 LKEKEQgKTGELNQLLNAVKSMQEKTVVFQqERDQVMLALKQKQMENTALQNEVQRLR-DKEFRSNQELERLRNHLLESE 1591
Cdd:PRK03918   330 IKELEE-KEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1592 DSYTREALAAEDREAKLRKKVTVLEE-KLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYAL 1670
Cdd:PRK03918   408 SKITARIGELKKEIKELKKAIEELKKaKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1671 SLANLQMV---------LEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDV 1741
Cdd:PRK03918   488 VLKKESELiklkelaeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDE 567

                          410       420       430
                   ....*....|....*....|....*....|
gi 1012519614 1742 KEEQIEELKRQ-NELRQEMLDDVQKKLMSL 1770
Cdd:PRK03918   568 LEEELAELLKElEELGFESVEELEERLKEL 597
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
170-544 1.30e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  170 QQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRsQEIDDHQHEMSVLQNAHQQKLTEI 249
Cdd:COG4717    108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELE-EELEELEAELAELQEELEELLEQL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  250 SRRHREELSDYEERIEELENLLQQggsgvIETDLSKIYEMQKTIQVlQIEKVESTKKMEQLEDKIKD------------- 316
Cdd:COG4717    187 SLATEEELQDLAEELEELQQRLAE-----LEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEarlllliaaalla 260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  317 --------------------------------INKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLecsklqpsav 364
Cdd:COG4717    261 llglggsllsliltiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGL---------- 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  365 kqsDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSL-----AEDNLKLKMRIEVLEKEKSLLsQEKEE 439
Cdd:COG4717    331 ---PPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlaeagVEDEEELRAALEQAEEYQELK-EELEE 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  440 LQMSLLKLNNEYEVIKSTATRDiSLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQ-EATKHMILIKDQLS 518
Cdd:COG4717    407 LEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAEL 485

                          410       420
                   ....*....|....*....|....*.
gi 1012519614  519 KQQNEGDSIISKLKQDLNDEKKRVHQ 544
Cdd:COG4717    486 RELAEEWAALKLALELLEEAREEYRE 511
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-671 1.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  463 SLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEgdsiISKLKQDLNDEKKRV 542
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE----LAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  543 HQLEDD---------KMDITKELDV--QKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEH 611
Cdd:COG4942    100 EAQKEElaellralyRLGRQPPLALllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1012519614  612 IRQNEEELSRI------RNELMQSLNQDsnsnfkdtlLKEREAEVRNLKQNLSELEQLNENLKKVA 671
Cdd:COG4942    180 LAELEEERAALealkaeRQKLLARLEKE---------LAELAAELAELQQEAEELEALIARLEAEA 236
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 482-1229 1.95e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 1.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  482 LNQSISEKETLIAEIEELDRQNQEATKhmilikdQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDkmdITKELDVQKE 561
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDET-------LIASRQEERQETSAELNQLLRTLDDQWKEKRDE---LNGELSAADA 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  562 KLiqsevalndlhltkQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQdsnsnfkdt 641
Cdd:pfam12128  316 AV--------------AKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQD--------- 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  642 llKEREAEVRNLK---QNLSELEQLNENLKKVafdvKMENEKLVLACEDVRHQLEeclagnNQLSLEKNTIVETLKMEKG 718
Cdd:pfam12128  373 --VTAKYNRRRSKikeQNNRDIAGIKDKLAKI----REARDRQLAVAEDDLQALE------SELREQLEAGKLEFNEEEY 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  719 EIEAELCWAKKRLleeaNKYEKTIEELSNARNlNTSALQLEHEHLIKLNQKKD---MEIAELKKNIEQMDTDHKETKDVL 795
Cdd:pfam12128  441 RLKSRLGELKLRL----NQATATPELLLQLEN-FDERIERAREEQEAANAEVErlqSELRQARKRRDQASEALRQASRRL 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  796 SSSLEEQKQL-TQLINKKEIFIEKLKERSSKLQEELDKysqaLRKNEILRQTIEEKDRSLGSMKEENNHLQEELerlree 874
Cdd:pfam12128  516 EERQSALDELeLQLFPQAGTLLHFLRKEAPDWEQSIGK----VISPELLHRTDLDPEVWDGSVGGELNLYGVKL------ 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  875 qsRTAPVADPKTLDSVTELASEVSQLntikehlEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHT 954
Cdd:pfam12128  586 --DLKRIDVPEWAASEEELRERLDKA-------EEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLR 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  955 QLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKEREL----- 1029
Cdd:pfam12128  657 RLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLallka 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1030 EIKLLNEKNISLTKQIDQLSKDEVGKL---TQIIQQKDLEIQALHARISSTSHTQDVV--YLQQQLQAYAMEREKVFAVL 1104
Cdd:pfam12128  737 AIAARRSGAKAELKALETWYKRDLASLgvdPDVIAKLKREIRTLERKIERIAVRRQEVlrYFDWYQETWLQRRPRLATQL 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1105 NEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRfessgqdmfretiqnLSRIIREKDIEIDALSQkcqtlLA 1184
Cdd:pfam12128  817 SNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVR---------------LSENLRGLRCEMSKLAT-----LK 876

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1012519614 1185 VLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMT 1229
Cdd:pfam12128  877 EDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIA 921
COG5022 COG5022
Myosin heavy chain [General function prediction only];
388-670 2.02e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 50.08  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  388 RLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLS-QEKEELQMSLLKLNNEYE-------VIKSTAT 459
Cdd:COG5022    758 RYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSlLGSRKEYRSYLACIIKLQktikrekKLRETEE 837

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  460 RDISLDSE--LHDLRLNLEAKEQ---ELNQSISEKETliAEIEELDRQNQEaTKHMILIKDQLSKQQNEGDSIISKLKQD 534
Cdd:COG5022    838 VEFSLKAEvlIQKFGRSLKAKKRfslLKKETIYLQSA--QRVELAERQLQE-LKIDVKSISSLKLVNLELESEIIELKKS 914

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  535 LNDE--KKRVHQLEDD----KMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLEL 608
Cdd:COG5022    915 LSSDliENLEFKTELIarlkKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSEL 994

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1012519614  609 KEHIR------------QNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLS-ELEQLNENLKKV 670
Cdd:COG5022    995 KNFKKelaelskqygalQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLlENNQLQARYKAL 1069
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 170-801 2.14e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  170 QQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEI 249
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  250 SRRHREELSDYEERIEELENllqqggsgvietdlskiyemqktiqvlqiEKVESTKKMEQLEDKIKDINKKLSSAENDRD 329
Cdd:COG1196    325 LAELEEELEELEEELEELEE-----------------------------ELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  330 ILRREQEQLNVEKRQIMEECENLKlecSKLQPSAVKQSDTMTEKERILAQsasveevfRLQQALSDAENEIMRLSSLNQD 409
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELA---AQLEELEEAEEALLERLERLEEE--------LEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  410 NSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEK 489
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  490 ETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLndeKKRVHQLEDDKMDITKELDVQKEKLIQSEVA 569
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK---AGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  570 LNDlhltkqKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQ--DSNSNFKDTLLKERE 647
Cdd:COG1196    602 DLV------ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAggSLTGGSRRELLAALL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  648 AEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCwA 727
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL-E 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  728 KKRLLEEANKYEKTIEELSNARNL----NTSALQlEHEHLIK-----LNQKKDME--IAELKKNIEQMDtdhKETKDVLS 796
Cdd:COG1196    755 ELPEPPDLEELERELERLEREIEAlgpvNLLAIE-EYEELEErydflSEQREDLEeaRETLEEAIEEID---RETRERFL 830


                   ....*
gi 1012519614  797 SSLEE 801
Cdd:COG1196    831 ETFDA 835
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1384-1651 2.81e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.35  E-value: 2.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1384 RKEHEQTDSEI---KQLKEKQDVLQKLLkEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERIlilEMDIGKL 1460
Cdd:pfam17380  302 RQEKEEKAREVerrRKLEEAEKARQAEM-DRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEI---AMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1461 KGENEKIVETYRGKETEYQALqETNMKFSMMLREKEfecHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVV 1540
Cdd:pfam17380  378 RELERLQMERQQKNERVRQEL-EAARKVKILEEERQ---RKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRL 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1541 FQQERDQVMLALKQKQMEntalQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLV 1620
Cdd:pfam17380  454 EEQERQQQVERLRQQEEE----RKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAI 529

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1012519614 1621 SSSNAMENASHQASVQVE-----SLQEQLNVVSKQR 1651
Cdd:pfam17380  530 YEEERRREAEEERRKQQEmeerrRIQEQMRKATEER 565
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1504-1767 4.43e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 4.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1504 EKALAFEQLlkeKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERL 1583
Cdd:COG1196    210 EKAERYREL---KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1584 RNHLLEsedsytrealaAEDREAKLRKKVTVLEEKLvsssnamenashqasvqvESLQEQLNVVSKQRDETALQLSVSQE 1663
Cdd:COG1196    287 QAEEYE-----------LLAELARLEQDIARLEERR------------------RELEERLEELEEELAELEEELEELEE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1664 QVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEwkknAENLEGKVISLQECLDEANAALDSASRLTEQLDVKE 1743
Cdd:COG1196    338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA----EEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          250       260
                   ....*....|....*....|....
gi 1012519614 1744 EQIEELKRQNELRQEMLDDVQKKL 1767
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEE 437
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 264-1033 4.47e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  264 IEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQ--IEKVESTKK-MEQLEDKIKDINKKLSSAENDRDILRREQEQLNV 340
Cdd:TIGR01612 1623 LKETESIEKKISSFSIDSQDTELKENGDNLNSLQefLESLKDQKKnIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGII 1702

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  341 EKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQD-------NSLA 413
Cdd:TIGR01612 1703 EKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskEPIT 1782

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  414 EDNLK---------LKMRIEVLEKEKSLLSQ-EKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDlrlnleakeqELN 483
Cdd:TIGR01612 1783 YDEIKntrinaqneFLKIIEIEKKSKSYLDDiEAKEFDRIINHFKKKLDHVNDKFTKEYSKINEGFD----------DIS 1852

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  484 QSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSI---ISKLKQDLNDEKKR---VHQLEDDKMDITKELD 557
Cdd:TIGR01612 1853 KSIENVKNSTDENLLFDILNKTKDAYAGIIGKKYYSYKDEAEKIfinISKLANSINIQIQNnsgIDLFDNINIAILSSLD 1932

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  558 VQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQ------ESNVSIQKENLELKEHIRQNEE----------ELSR 621
Cdd:TIGR01612 1933 SEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQdlhkkeQDTLNIIFENQQLYEKIQASNElkdtlsdlkyKKEK 2012

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  622 IRNEL------MQSLNQDS-NSNFKDTLLKEREAEvrNLKQNLSELEQLNENLKkVAFDVKMENEKL---VLACEDVRHQ 691
Cdd:TIGR01612 2013 ILNDVklllhkFDELNKLScDSQNYDTILELSKQD--KIKEKIDNYEKEKEKFG-IDFDVKAMEEKFdndIKDIEKFENN 2089

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  692 LEECLAGNNQLSLEKNTIVETLK--------------------MEKGEIEAELCWAKKRLL------------------- 732
Cdd:TIGR01612 2090 YKHSEKDNHDFSEEKDNIIQSKKklkelteafnteikiiedkiIEKNDLIDKLIEMRKECLlfsyatlvetlkskvinhs 2169

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  733 ---EEANKYEKT----IEELSNARNLNTSALQLEH------EHLIKLNQ----------KKDMEIAELKKNIEQMDTDHK 789
Cdd:TIGR01612 2170 efiTSAAKFSKDffefIEDISDSLNDDIDALQIKYnlnqtkKHMISILAdatkdhnnliEKEKEATKIINNLTELFTIDF 2249

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  790 ETKDV----------------LSSSLEEQKQLTQ-----------LINKKEIFIEK-----LKERSSKLQEELDKYSQ-- 835
Cdd:TIGR01612 2250 NNADAdilhnnkiqiiyfnseLHKSIESIKKLYKkinafkllnisHINEKYFDISKefdniIQLQKHKLTENLNDLKEid 2329

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  836 ---ALRKNEILRQTIEEKDRSLGSMKE--ENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQL---------- 900
Cdd:TIGR01612 2330 qyiSDKKNIFLHALNENTNFNFNALKEiyDDIINRENKADEIENINNKENENIMQYIDTITKLTEKIQDIlifvttyend 2409

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  901 -NTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNA-------------THTQLFLEKDEEIKS 966
Cdd:TIGR01612 2410 nNIIKQHIQDNDENDVSKIKDNLKKTIQSFQEILNKIDEIKAQFYGGNNINNiiitisqnandvkNHFSKDLTIENELIQ 2489

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614  967 LQKTIEQIKTQLHEER--QDIQTDNSdIFQETKVQSLNIENGSEKHDLSKA-ETERLVKGIK--ERELEIKL 1033
Cdd:TIGR01612 2490 IQKRLEDIKNAAHEIRseQITKYTNA-IHNHIEEQFKKIENNSNKDEVYKInEIDNIIEKIInyNKEPEVKL 2560
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1202-1752 5.62e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 5.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1202 QFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLK 1281
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1282 NFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDAT 1361
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1362 IRTLQENNHRLSDSIAATSELERKEhEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQ 1441
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLE-RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1442 AVTNLKERILILEmDIGKLKGENEKIVETYRGKETEYQALQETNMKFSmmLREKEFECHSMKEKALAFEQLLKEKEQGKT 1521
Cdd:COG1196    472 AALLEAALAELLE-ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG--LRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1522 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAA 1601
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1602 EDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLnvvSKQRDETALQLSVSQEQVKQYALSLANLQMVLEH 1681
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL---AALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1012519614 1682 FQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQEcLDEANAALDSASRLTEQLDVKEEQIEELKRQ 1752
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE-EELLEEEALEELPEPPDLEELERELERLERE 775
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 207-928 1.06e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  207 QSEICKLQNIIKELKQNRSQEIDDHQHEMSV---LQNAHQQKLTEI--SRRHREE-LSDYEERIEEL-------ENLLQQ 273
Cdd:pfam15921  109 RQSVIDLQTKLQEMQMERDAMADIRRRESQSqedLRNQLQNTVHELeaAKCLKEDmLEDSNTQIEQLrkmmlshEGVLQE 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  274 GGSGVI---ETDLSKIYEmQKTIQVLQIEKVES--TKKMEQLEDKIKDINKKLSSAENDRDILRRE-QEQLNVEKRQIME 347
Cdd:pfam15921  189 IRSILVdfeEASGKKIYE-HDSMSTMHFRSLGSaiSKILRELDTEISYLKGRIFPVEDQLEALKSEsQNKIELLLQQHQD 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  348 ECENLKLE-------CSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQaLSDAENEIMRL-SSLNQDNSLAEDnlkl 419
Cdd:pfam15921  268 RIEQLISEheveitgLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ-LSDLESTVSQLrSELREAKRMYED---- 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  420 kmRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEvikstatrdiSLDSELHDLRLNLEAKEQEL------NQSISEKE--- 490
Cdd:pfam15921  343 --KIEELEKQLVLANSELTEARTERDQFSQESG----------NLDDQLQKLLADLHKREKELslekeqNKRLWDRDtgn 410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  491 --TLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLkQDLNDEKKRVHQLeddkmdiTKELDVQKEKLIQSEV 568
Cdd:pfam15921  411 siTIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI-QGKNESLEKVSSL-------TAQLESTKEMLRKVVE 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  569 ALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREA 648
Cdd:pfam15921  483 ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  649 EVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEEClagnNQLSLEKNTIVETLKMEKGEIEAElcwaK 728
Cdd:pfam15921  563 VIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEF----KILKDKKDAKIRELEARVSDLELE----K 634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  729 KRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQ---- 804
Cdd:pfam15921  635 VKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQtrnt 714

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  805 -----------------LTQLINKKEIFIEKLKERSSKLQEELdkySQALRKNEILRQTIEEKDRSLGSMKEENNHLQEE 867
Cdd:pfam15921  715 lksmegsdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAM---TNANKEKHFLKEEKNKLSQELSTVATEKNKMAGE 791

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1012519614  868 LERLREEQSRtapvadpktldsvteLASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQL 928
Cdd:pfam15921  792 LEVLRSQERR---------------LKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 418-640 1.09e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  418 KLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEyevIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIE 497
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERR---IAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  498 ELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTK 577
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  578 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKD 640
Cdd:COG4942    188 AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
PTZ00121 PTZ00121
MAEBL; Provisional
 221-666 1.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  221 KQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEK 300
Cdd:PTZ00121  1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA 1492

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  301 VESTKKMEQLEDKIKDINK--KLSSAENDR--DILRREQEQLNVEKRQIMEEC----ENLKLECSKLQPSAVKQSDTMTE 372
Cdd:PTZ00121  1493 EEAKKKADEAKKAAEAKKKadEAKKAEEAKkaDEAKKAEEAKKADEAKKAEEKkkadELKKAEELKKAEEKKKAEEAKKA 1572

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  373 KERILAQSASVEEVFRLQQALSD------AENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMS--L 444
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEevmklyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAeeL 1652

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  445 LKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK---------- 514
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKkaeeenkika 1732

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  515 DQLSKQQNEGDSIISKLKQDlNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHL------TKQKLEDKVENLV 588
Cdd:PTZ00121  1733 EEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRrmevdkKIKDIFDNFANII 1811

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  589 D-------QLNKSQESNVSIQKENLELKEHIRQNEEELSR----IRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNl 657
Cdd:PTZ00121  1812 EggkegnlVINDSKEMEDSAIKEVADSKNMQLEEADAFEKhkfnKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEI- 1890


                   ....*....
gi 1012519614  658 selEQLNEN 666
Cdd:PTZ00121  1891 ---EKIDKD 1896
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 436-941 1.28e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  436 EKEELQMSLLKLNNEYEVIkSTATRDISLDSELHDLRLNLEAKE---------QELNQSISEKET----LIAEIEELDRQ 502
Cdd:pfam05483  177 EREETRQVYMDLNNNIEKM-ILAFEELRVQAENARLEMHFKLKEdhekiqhleEEYKKEINDKEKqvslLLIQITEKENK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  503 NQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLED 582
Cdd:pfam05483  256 MKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  583 KVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNEL----MQSLNQDSNSNFKDTLLKEREAEVRNLKQNLS 658
Cdd:pfam05483  336 QMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLkiitMELQKKSSELEEMTKFKNNKEVELEELKKILA 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  659 ELEQL---NENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEaelcwakkrlleea 735
Cdd:pfam05483  416 EDEKLldeKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE-------------- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  736 NKYEKTIEELSNarnlnTSALQLEHEhliKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIF 815
Cdd:pfam05483  482 KEKLKNIELTAH-----CDKLLLENK---ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  816 IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSM------KEENNHLQEELERLREEQSRTAPVADPKTLDS 889
Cdd:pfam05483  554 REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKcnnlkkQIENKNKNIEELHQENKALKKKGSAENKQLNA 633

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  890 VTELASEVS-QLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDE 941
Cdd:pfam05483  634 YEIKVNKLElELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADE 686
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 204-441 1.39e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  204 NSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDL 283
Cdd:pfam12128  660 DEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIA 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  284 SKIYEMQKTIQVLQIEKVESTKK-------MEQLEDKIKDINKKLSSAENDRDILRR----EQEQLNVEKRQIMEECENL 352
Cdd:pfam12128  740 ARRSGAKAELKALETWYKRDLASlgvdpdvIAKLKREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNI 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  353 KLECSKLQPS-AVKQSDTMTEKERILAQS-ASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEK 430
Cdd:pfam12128  820 ERAISELQQQlARLIADTKLRRAKLEMERkASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLK 899

                          250
                   ....*....|.
gi 1012519614  431 SLLSQEKEELQ 441
Cdd:pfam12128  900 LKRDYLSESVK 910
PRK01156 PRK01156
chromosome segregation protein; Provisional
 410-986 1.58e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  410 NSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEK 489
Cdd:PRK01156   162 NSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSAL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  490 ETLIAEIEELDRQNQEATK---------------------HMILIKDQLSKQQNEGDSIIsKLKQDLNDEKKrvhQLEDD 548
Cdd:PRK01156   242 NELSSLEDMKNRYESEIKTaesdlsmeleknnyykeleerHMKIINDPVYKNRNYINDYF-KYKNDIENKKQ---ILSNI 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  549 KMDITKELDVQKeKLIQSEVALNDlHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQ 628
Cdd:PRK01156   318 DAEINKYHAIIK-KLSVLQKDYND-YIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  629 SLN-QDSNSNFKDTLLKEREAEVRNLKQNLSELEQ----LNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLS 703
Cdd:PRK01156   396 ILKiQEIDPDAIKKELNEINVKLQDISSKVSSLNQriraLRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYN 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  704 LEKNTIVEtlKMEKGEIEAELCWAKKRLLEEANKY--EKTIEELSNARNLNTSAlqlehEHLIKLNQKKDMEIAELKKNI 781
Cdd:PRK01156   476 EKKSRLEE--KIREIEIEVKDIDEKIVDLKKRKEYleSEEINKSINEYNKIESA-----RADLEDIKIKINELKDKHDKY 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  782 EQMDTDHKETK-DVLSSSLEEQKQLTQLINKkeIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEE-KDRSLGSMKE 859
Cdd:PRK01156   549 EEIKNRYKSLKlEDLDSKRTSWLNALAVISL--IDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSyIDKSIREIEN 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  860 ENNHLQEELERlreeqsrtapvadpktldsVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSlqeqkkeM 939
Cdd:PRK01156   627 EANNLNNKYNE-------------------IQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI-------E 680

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1012519614  940 DEFRYQHEQMNATHTQLFlEKDEEIKSLQKTIEQIKTQLHEERQDIQ 986
Cdd:PRK01156   681 DNLKKSRKALDDAKANRA-RLESTIEILRTRINELSDRINDINETLE 726
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1510-1759 1.61e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1510 EQLLKEKEQGK-------TGELNQLLNAVKS-MQEKTVVFQQERDQV------MLALKQKQMENTALQNEVQRLRDKEFR 1575
Cdd:PRK10929    86 QQLNNERDEPRsvppnmsTDALEQEILQVSSqLLEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQLNEIERRLQTLGT 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1576 SNQELERLRNHLLESEdsytrealaaedrEAKLRKKVTVLEEKLVSSSNAMENA----------SHQASVQVESLQEQLN 1645
Cdd:PRK10929   166 PNTPLAQAQLTALQAE-------------SAALKALVDELELAQLSANNRQELArlrselakkrSQQLDAYLQALRNQLN 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1646 VVSKQRDETALqlsvsqEQVKQYALSLANL-QMVLEHFQQEEkaMYSAELEKQKQ---LIAEWKKNAENLEGKVISLQEC 1721
Cdd:PRK10929   233 SQRQREAERAL------ESTELLAEQSGDLpKSIVAQFKINR--ELSQALNQQAQrmdLIASQQRQAASQTLQVRQALNT 304

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1012519614 1722 LDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEM 1759
Cdd:PRK10929   305 LREQSQWLGVSNALGEALRAQVARLPEMPKPQQLDTEM 342
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 38-841 1.68e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.89  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   38 LMEGTEEVEELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQ 117
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSK 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  118 DQLLKLQSAAQSVpsgagvpattassSFAYGISHHPSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTS 197
Cdd:pfam02463  258 QEIEKEEEKLAQV-------------LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  198 KAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQhEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSG 277
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEE-ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  278 VIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRqimEECENLKLECS 357
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK---SEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  358 KLQPSAVKQSDTMTEKERILAQSASVE------------EVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEV 425
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSglkvllalikdgVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  426 LEKEK-------SLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEE 498
Cdd:pfam02463  561 EERQKlvralteLPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  499 LDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQ 578
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  579 KLEDKVENLVDQLNKSqesnvsIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSnsnfkdtLLKEREAEVRNLKQNLS 658
Cdd:pfam02463  721 ELLADRVQEAQDKINE------ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS-------LKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  659 ELEQLNENLKKVAFDVKMENEKLVLACEdvrhQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKY 738
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAE----LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  739 EKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLIN-----KKE 813
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEepeelLLE 943

                          810       820
                   ....*....|....*....|....*...
gi 1012519614  814 IFIEKLKERSSKLQEELDKYSQALRKNE 841
Cdd:pfam02463  944 EADEKEKEENNKEEEEERNKRLLLAKEE 971
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1523-1752 2.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1523 ELNQLLNAVKSMQEktvvfQQERDQVMLALKQKQMENTALQNEVQRLRDK--EFRSNQELERLRNHLLESEDSYTReala 1600
Cdd:COG4913    236 DLERAHEALEDARE-----QIELLEPIRELAERYAAARERLAELEYLRAAlrLWFAQRRLELLEAELEELRAELAR---- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1601 AEDREAKLRKKVTVLEEKLVSSSNAMENASHQasvQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQmvle 1680
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGD---RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA---- 379

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012519614 1681 hfqqeekamysAELEKQKQLIAEWKKNAENLEgkvislQECLDEANAALDSASRLTEQLDVKEEQIEELKRQ 1752
Cdd:COG4913    380 -----------EEFAALRAEAAALLEALEEEL------EALEEALAEAEAALRDLRRELRELEAEIASLERR 434
PRK09039 PRK09039
peptidoglycan -binding protein;
1634-1766 3.35e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.96  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1634 SVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLehfqqeekAMYSAELEKQKQLIAEWKKNAENLEG 1713
Cdd:PRK09039    45 SREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASL--------SAAEAERSRLQALLAELAGAGAAAEG 116

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1012519614 1714 KVISLQECLDEANAALDSASRlteQLDVKEEQIEELKRQNELRQEMLDDVQKK 1766
Cdd:PRK09039   117 RAGELAQELDSEKQVSARALA---QVELLNQQIAALRRQLAALEAALDASEKR 166
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
640-1227 3.97e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  640 DTLLKEREAEVRNLKQ--NLSELEQLNENLKKV--AFDVKMEN-EKLVLACEDVRHQLEEclagNNQLSLEKNTIVETLK 714
Cdd:PRK03918   138 DAILESDESREKVVRQilGLDDYENAYKNLGEVikEIKRRIERlEKFIKRTENIEELIKE----KEKELEEVLREINEIS 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  715 MEKGEIEAELCWAKKRLLEeankYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMeIAELKKNIEQMDTDHKEtkdv 794
Cdd:PRK03918   214 SELPELREELEKLEKEVKE----LEELKEEIEELEKELESLEGSKRKLEEKIRELEER-IEELKKEIEELEEKVKE---- 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  795 lsssLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELER---- 870
Cdd:PRK03918   285 ----LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEleer 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  871 ------LREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRY 944
Cdd:PRK03918   361 helyeeAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPV 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  945 QHEQMNATHTQLFLEK-DEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSL--------NIENGSEKHDLSKA 1015
Cdd:PRK03918   441 CGRELTEEHRKELLEEyTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLkelaeqlkELEEKLKKYNLEEL 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1016 ETerlvkgiKERELEikLLNEKNISLTKQIDQLsKDEVGKLTQIIQQKDLEIQALHARISSTSHtqdvvyLQQQLQAYAM 1095
Cdd:PRK03918   521 EK-------KAEEYE--KLKEKLIKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAE------LLKELEELGF 584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1096 EREKvfaVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFE-----SSGQDMFRETIQNLSRIIREKDI 1170
Cdd:PRK03918   585 ESVE---ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEelaetEKRLEELRKELEELEKKYSEEEY 661

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1012519614 1171 E-IDALSQKCQTLLAVLQTSSTGNEaggvnsNQFEELLQERDKLKQQVKKMEEWKQQV 1227
Cdd:PRK03918   662 EeLREEYLELSRELAGLRAELEELE------KRREEIKKTLEKLKEELEEREKAKKEL 713
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 773-986 4.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  773 EIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKdr 852
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE-- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  853 slgsmKEENNHLQEELERLREEQSRTAPVA------DPKTLDSVTELASEVS-----QLNTIKEHLEEeIKHHQKIIEDQ 921
Cdd:COG4942     99 -----LEAQKEELAELLRALYRLGRQPPLAlllspeDFLDAVRRLQYLKYLAparreQAEELRADLAE-LAALRAELEAE 172

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1012519614  922 NQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQ 986
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1009-1619 5.45e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 5.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1009 KHDLSKAETERLVKGIKERELEIK-LLNEknisLTKQIDQLSKD-----EVGKLTQIIQQKDLEIQALHARisstshtqd 1082
Cdd:COG1196    169 KYKERKEEAERKLEATEENLERLEdILGE----LERQLEPLERQaekaeRYRELKEELKELEAELLLLKLR--------- 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1083 vvYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFES--SGQDMFRETIQN 1160
Cdd:COG1196    236 --ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQDIARLEERRRE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1161 LSRIIREKDIEIDALSQKCQTLLAVLQTSstgNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQ 1240
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEELEEL---EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1241 LQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASL 1320
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1321 LTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELErKEHEQTDSEIKQLKEK 1400
Cdd:COG1196    471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE-AAYEAALEAALAAALQ 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1401 QDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILI------LEMDIGKLKGENEKIVETYRGK 1474
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvasdLREADARYYVLGDTLLGRTLVA 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1475 ETEYQALqETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQ 1554
Cdd:COG1196    630 ARLEAAL-RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1012519614 1555 KQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDRE---AKLRKKVTVLEEKL 1619
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREI 776
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 255-990 6.20e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 6.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  255 EELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKtiQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDIL--R 332
Cdd:TIGR00618  212 CMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK--REAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERInrA 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  333 REQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEI--------MRLS 404
Cdd:TIGR00618  290 RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIrdahevatSIRE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  405 SLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQmsllklnneyevikSTATRDISLDSELHDLRLNLEAKEQELnq 484
Cdd:TIGR00618  370 ISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQ--------------REQATIDTRTSAFRDLQGQLAHAKKQQ-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  485 sisEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQ-KEKL 563
Cdd:TIGR00618  434 ---ELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlCGSC 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  564 IQSEVALNDLHLTkQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELmQSLNQdsnsnfKDTLL 643
Cdd:TIGR00618  511 IHPNPARQDIDNP-GPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSF-SILTQ------CDNRS 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  644 KEREAEVRNLKQNLSELEQLNENLKKvafdvkmeneklVLACEDVRHQLEECLAGNNQ-LSLEKNTIVETLKMEKGEIEA 722
Cdd:TIGR00618  583 KEDIPNLQNITVRLQDLTEKLSEAED------------MLACEQHALLRKLQPEQDLQdVRLHLQQCSQELALKLTALHA 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  723 ELCWAKKRLLEEANKYEKTIEELSNARNLNtsalqlehehLIKLNQKKDMEIAELKKNIEQMDTDHKEtkdVLSSSLEEQ 802
Cdd:TIGR00618  651 LQLTLTQERVREHALSIRVLPKELLASRQL----------ALQKMQSEKEQLTYWKEMLAQCQTLLRE---LETHIEEYD 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  803 KQLTQLINKKEIFIEKLKERSSKLQEELDKYsQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRtapva 882
Cdd:TIGR00618  718 REFNEIENASSSLGSDLAAREDALNQSLKEL-MHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN----- 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  883 dpktldsvTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMnathtqlfLEKDE 962
Cdd:TIGR00618  792 --------RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQ--------LLKYE 855

                          730       740
                   ....*....|....*....|....*...
gi 1012519614  963 EIKSLQKTIEQIKTQLHEERQDIQTDNS 990
Cdd:TIGR00618  856 ECSKQLAQLTQEQAKIIQLSDKLNGINQ 883
PTZ00121 PTZ00121
MAEBL; Provisional
 665-1400 6.98e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  665 ENLKKVAFDVKMENEKLVLA---CEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAkkrllEEANKYE-- 739
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAvkkAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-----EEARKADel 1283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  740 KTIEELSNARNLNTSALQLEHEHLIKLNQKKDmEIAELKKNIEQMdtdhKETKDVLSSSLEEQKQLTQLINKK-EIFIEK 818
Cdd:PTZ00121  1284 KKAEEKKKADEAKKAEEKKKADEAKKKAEEAK-KADEAKKKAEEA----KKKADAAKKKAEEAKKAAEAAKAEaEAAADE 1358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  819 LKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSlgsmkEENNHLQEELERLREEQSRTApvADPKTLDSVTELASEVS 898
Cdd:PTZ00121  1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKADELKKAA--AAKKKADEAKKKAEEKK 1431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  899 QLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQmnATHTQLFLEKDEEIKslqKTIEQIKTQL 978
Cdd:PTZ00121  1432 KADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--AKKADEAKKKAEEAK---KKADEAKKAA 1506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  979 HEERQDIQTDNSDifQETKVQSL-NIENGSEKHDLSKAETERLVKGIKERElEIKLLNEKnisltKQIDQLSKDEVGKLT 1057
Cdd:PTZ00121  1507 EAKKKADEAKKAE--EAKKADEAkKAEEAKKADEAKKAEEKKKADELKKAE-ELKKAEEK-----KKAEEAKKAEEDKNM 1578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1058 QIIQQKDLEiQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHlKTEYHKMMDIVAAKEAALIKLQD 1137
Cdd:PTZ00121  1579 ALRKAEEAK-KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK-KVEQLKKKEAEEKKKAEELKKAE 1656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1138 ENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNE----------AGGVNSNQFEELL 1207
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEekkkaeelkkAEEENKIKAEEAK 1736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1208 QERDKLK---QQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYT--------GLIQSYEQN 1276
Cdd:PTZ00121  1737 KEAEEDKkkaEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKikdifdnfANIIEGGKE 1816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1277 ETKLKNFGQELAQvqHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQ 1356
Cdd:PTZ00121  1817 GNLVINDSKEMED--SAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKID 1894

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1012519614 1357 ----EKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEK 1400
Cdd:PTZ00121  1895 kddiEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIKISKK 1942
PLN02939 PLN02939
transferase, transferring glycosyl groups
 979-1282 7.46e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 7.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  979 HEERQDIQTDNSDIFQETKVQslniENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEvGKLTQ 1058
Cdd:PLN02939    96 DHNRASMQRDEAIAAIDNEQQ----TNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEK-EALQG 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1059 IIQQKDLEIQALHARISSTSHTQ-DVVYLQQQLQAY----AMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALI 1133
Cdd:PLN02939   171 KINILEMRLSETDARIKLAAQEKiHVEILEEQLEKLrnelLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELI 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1134 KLQDENKKLSTR------FESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELL 1207
Cdd:PLN02939   251 EVAETEERVFKLekerslLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLR 330

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1012519614 1208 QERDKLKQQVKKMEEWKQQvMTTVQNMQHESAQLQEELHQlqaqvlVDSDNNSKLQVdYTGLIQSYEQNETKLKN 1282
Cdd:PLN02939   331 DKVDKLEASLKEANVSKFS-SYKVELLQQKLKLLEERLQA------SDHEIHSYIQL-YQESIKEFQDTLSKLKE 397
GRAB pfam10375
GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type ...
 1773-1818 8.19e-04

GRAB domain; The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type proteins. This domain is related to the GRIP domain, but the conserved tyrosine residue found at position 4 in all GRIP domains is replaced by a leucine residue. The Arf small GTPase is localized to the cis-Golgi where it recruits proteins via their GRAB domain, as part of the transport of cargo from the endoplasmic reticulum to the plasma membrane.


Pssm-ID: 431241  Cd Length: 49  Bit Score: 39.13  E-value: 8.19e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1012519614 1773 SSEGKVDKVLMRNLFIGHFHTPK--NQRHEVLRLMGSILGVRREEMEQ 1818
Cdd:pfam10375    1 SSEDTVDRQLVTNLLLSFLSIPRgdTKKFEILQLIANLLEWDDEQREQ 48
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 480-860 9.57e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.43  E-value: 9.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  480 QELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQ-------QNEGDSIISKL---KQDLNDEKKRVHQLEDDK 549
Cdd:pfam10174  296 QELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKeqraailQTEVDALRLRLeekESFLNKKTKQLQDLTEEK 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  550 MDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQ-------------KENLELKEHI---- 612
Cdd:pfam10174  376 STLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQtdssntdtalttlEEALSEKERIierl 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  613 RQNEEELSRIRNELMQSLNQDsNSNFKDTL------LKEREAEVRNLKQNLSELEQlnENLKKVAFDVKMENEklvlace 686
Cdd:pfam10174  456 KEQREREDRERLEELESLKKE-NKDLKEKVsalqpeLTEKESSLIDLKEHASSLAS--SGLKKDSKLKSLEIA------- 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  687 dVRHQLEECLAGNNQLSLEKNT-IVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNA---------------RN 750
Cdd:pfam10174  526 -VEQKKEECSKLENQLKKAHNAeEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGIlrevenekndkdkkiAE 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  751 LNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQkqltqlinkkeifIEKLKERSSKLQEEL 830
Cdd:pfam10174  605 LESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQ-------------LEELMGALEKTRQEL 671

                          410       420       430
                   ....*....|....*....|....*....|
gi 1012519614  831 DKYSQALRKNEilrQTIEEKDRSLGSMKEE 860
Cdd:pfam10174  672 DATKARLSSTQ---QSLAEKDGHLTNLRAE 698
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
297-724 1.04e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  297 QIEKVEST---KKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNV---EKRQIMEECENLKLECSKLQpsavkQSDTM 370
Cdd:PRK02224   195 QIEEKEEKdlhERLNGLESELAELDEEIERYEEQREQARETRDEADEvleEHEERREELETLEAEIEDLR-----ETIAE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  371 TEKERilaqSASVEEVFRLQQALSDAENEIM-RLSSLNQDNSLAEDnlkLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 449
Cdd:PRK02224   270 TERER----EELAEEVRDLRERLEELEEERDdLLAEAGLDDADAEA---VEARREELEDRDEELRDRLEECRVAAQAHNE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  450 EYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMIL-------IKDQLSKQQN 522
Cdd:PRK02224   343 EAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgnaedFLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  523 EGDSIISKLKQDLNDEKKRVHQ----LEDDK-------------MDITKELDVQKEKLiqsEVALNDLHLTKQKLEDKVE 585
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEaealLEAGKcpecgqpvegsphVETIEEDRERVEEL---EAELEDLEEEVEEVEERLE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  586 NLVDQlnKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREA------------EVRNL 653
Cdd:PRK02224   500 RAEDL--VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAaeaeeeaeeareEVAEL 577

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1012519614  654 KQNLSELEQLNENLKKVAfdvkmENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAEL 724
Cdd:PRK02224   578 NSKLAELKERIESLERIR-----TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1514-1777 1.15e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1514 KEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQEL-----ERLRNHLL 1588
Cdd:PLN02939   120 KDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIklaaqEKIHVEIL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1589 ESEDSYTREALAAE-----DREAKLRKKVTVLEEKLVSSSNAMEnASHQASVQVESLQEQLNVVSKQRD--ETALQ---- 1657
Cdd:PLN02939   200 EEQLEKLRNELLIRgategLCVHSLSKELDVLKEENMLLKDDIQ-FLKAELIEVAETEERVFKLEKERSllDASLReles 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1658 -LSVSQEQV-KQYALSLANLQMVLEHFQqeekAMYSAELEKQKQLIAEWKKNaENLEGKVISLQECLDEANAALDSASR- 1734
Cdd:PLN02939   279 kFIVAQEDVsKLSPLQYDCWWEKVENLQ----DLLDRATNQVEKAALVLDQN-QDLRDKVDKLEASLKEANVSKFSSYKv 353

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1012519614 1735 --LTEQLDVKEEQI----EELKRQNELRQEMLDDVQKKLMSLANSSEGK 1777
Cdd:PLN02939   354 elLQQKLKLLEERLqasdHEIHSYIQLYQESIKEFQDTLSKLKEESKKR 402
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 528-745 1.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  528 ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKsqesnvsIQKENLE 607
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE-------LEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  608 LKEHIRQNEEELSRIRNELMQSLNQD------SNSNFKDT---------LLKEREAEVRNLKQNLSELEQLNENLKKvaf 672
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPplalllSPEDFLDAvrrlqylkyLAPARREQAEELRADLAELAALRAELEA--- 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  673 dvkmENEKLvlacEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELcwakKRLLEEANKYEKTIEEL 745
Cdd:COG4942    172 ----ERAEL----EALLAELEEERAALEALKAERQKLLARLEKELAELAAEL----AELQQEAEELEALIARL 232
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
255-749 1.37e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.88  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  255 EELSDYEERIEELENLLQQggsgvIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRRE 334
Cdd:PRK02224   241 EVLEEHEERREELETLEAE-----IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEAR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  335 QEQLNVEKrqimEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASveevfRLQQALSDAENEImrlsslnqdNSLAE 414
Cdd:PRK02224   316 REELEDRD----EELRDRLEECRVAAQAHNEEAESLREDADDLEERAE-----ELREEAAELESEL---------EEARE 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  415 DNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTAtrdisldSELHDLRLNLEAKEQELNQSISEKETLIA 494
Cdd:PRK02224   378 AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER-------DELREREAELEATLRTARERVEEAEALLE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  495 E---------------IEELDRQNQEATKHMILIkDQLSKQQNEGDSIISKLKqDLNDEKKRVHQLEDDKMDITKELDVQ 559
Cdd:PRK02224   451 AgkcpecgqpvegsphVETIEEDRERVEELEAEL-EDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  560 KEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNelmqslnqdsnsnfk 639
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------------- 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  640 dtlLKEREAEVRNLKQnlsELEQLNENLKKVAFDVKMENEKLVLACEDVRhQLEECLAGNN--QLSLEKNTIVETLKMEK 717
Cdd:PRK02224   594 ---IRTLLAAIADAED---EIERLREKREALAELNDERRERLAEKRERKR-ELEAEFDEARieEAREDKERAEEYLEQVE 666

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1012519614  718 GEIEaELCWAKKRLLEEANKYEKTIEELSNAR 749
Cdd:PRK02224   667 EKLD-ELREERDDLQAEIGAVENELEELEELR 697
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 214-839 1.39e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.67  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  214 QNIIKELKQNRSQEIDDHQHEMSVLQNAHqqklteisrrhreELSDYEERIEELENLLQ--QGGSGVIETDLSKIYEMQK 291
Cdd:pfam12128  213 PPKSRLNRQQVEHWIRDIQAIAGIMKIRP-------------EFTKLQQEFNTLESAELrlSHLHFGYKSDETLIASRQE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  292 TIQVLQIEKVESTKKME-QLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEE-CENLKLECSKLqPSAVKQSDT 369
Cdd:pfam12128  280 ERQETSAELNQLLRTLDdQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAdIETAAADQEQL-PSWQSELEN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 MTEKERILAQSA-SVEEVFRLQQALSDAEN--EIMRLSSlNQDNSLAEDNLKLKMRIEVLEKeksLLSQEKEELQMSLLK 446
Cdd:pfam12128  359 LEERLKALTGKHqDVTAKYNRRRSKIKEQNnrDIAGIKD-KLAKIREARDRQLAVAEDDLQA---LESELREQLEAGKLE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  447 LNNEYEVIKS------------TATRDISLDSELHDLRLnlEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK 514
Cdd:pfam12128  435 FNEEEYRLKSrlgelklrlnqaTATPELLLQLENFDERI--ERAREEQEAANAEVERLQSELRQARKRRDQASEALRQAS 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  515 DQLSKQQNEGD-----------SIISKLKQDLNDEKKRVHQL-------------EDDKMDITKELDVQKEKLIQSEVAL 570
Cdd:pfam12128  513 RRLEERQSALDelelqlfpqagTLLHFLRKEAPDWEQSIGKVispellhrtdldpEVWDGSVGGELNLYGVKLDLKRIDV 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  571 NDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQS-LNQDSNSNfkdtllkEREAE 649
Cdd:pfam12128  593 PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNArLDLRRLFD-------EKQSE 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  650 VRNLKQNL-SELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEEclagnnqLSLEKNTIVETLKMEKGEIEAELCWAK 728
Cdd:pfam12128  666 KDKKNKALaERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKRE-------ARTEKQAYWQVVEGALDAQLALLKAAI 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  729 KRLLEEANKYEKTIEElSNARNLntSALQLEHEHLIKLNQkkdmEIAELKKNIEQMDTDHKET----------------- 791
Cdd:pfam12128  739 AARRSGAKAELKALET-WYKRDL--ASLGVDPDVIAKLKR----EIRTLERKIERIAVRRQEVlryfdwyqetwlqrrpr 811

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  792 -----KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRK 839
Cdd:pfam12128  812 latqlSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRG 864
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 773-989 1.64e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  773 EIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKneiLRQTIEEKDR 852
Cdd:COG4942     35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA---QKEELAELLR 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  853 SLGSMKEENNHLQEELERLREEQSRTAPVAD---PKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLL 929
Cdd:COG4942    112 ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKylaPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  930 QSLQEQKKEMDEFRyqhEQMNATHTQLfLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDN 989
Cdd:COG4942    192 ALKAERQKLLARLE---KELAELAAEL-AELQQEAEELEALIARLEAEAAAAAERTPAAG 247
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
885-1303 1.64e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  885 KTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIE--DQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLfLEKDE 962
Cdd:COG4717     85 EKEEEYAELQEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPERLEELEERLEEL-RELEE 163

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  963 EIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETkvqslniengsekhdlsKAETERLVKGIKERELEIKLLNEKNISLT 1042
Cdd:COG4717    164 ELEELEAELAELQEELEELLEQLSLATEEELQDL-----------------AEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1043 KQIDQLSKD-EVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTE---- 1117
Cdd:COG4717    227 EELEQLENElEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKeaee 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1118 ---YHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIR-EKDIEIDALSQKCQTLLAvlqtsstgn 1193
Cdd:COG4717    307 lqaLPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEElEEELQLEELEQEIAALLA--------- 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1194 EAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESA-----QLQEELHQLQAQVlvdsdnnsklqvdytg 1268
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEaldeeELEEELEELEEEL---------------- 441

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1012519614 1269 liqsyEQNETKLKNFGQELAQVQHSIGQLCNTKDL 1303
Cdd:COG4717    442 -----EELEEELEELREELAELEAELEQLEEDGEL 471
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 477-669 1.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  477 AKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSI---ISKLKQDLNDEKKRVHQLEDDKMDIT 553
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALarrIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  554 KELDVQKEKLIQSEVAlndlhLTKQKLEDKVENLV-----DQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQ 628
Cdd:COG4942     97 AELEAQKEELAELLRA-----LYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1012519614  629 SLNQdsnsnfKDTLLKEREAEVRNLKQNLSELEQLNENLKK 669
Cdd:COG4942    172 ERAE------LEALLAELEEERAALEALKAERQKLLARLEK 206
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1352-1667 1.92e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1352 RKSLQEKDATIRTLQENNHRLSDS---------------------IAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKE 1410
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRRErekaeryqallkekreyegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1411 KDLLIKAKSDQLLSSNENFtNKVNENELLRqavtnlkeriliLEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSM 1490
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKI-KDLGEEEQLR------------VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1491 MLREKEFECHSMkEKALAFEQLLKEKEQGKTGELNQLLNAVKS-MQEKTVVFQQERDQVMLALKQKQM---ENTALQNEV 1566
Cdd:TIGR02169  330 EIDKLLAEIEEL-EREIEEERKRRDKLTEEYAELKEELEDLRAeLEEVDKEFAETRDELKDYREKLEKlkrEINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1567 QRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKvtvlEEKLVSSSNAMENASHqasvQVESLQEQLNV 1646
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ----EWKLEQLAADLSKYEQ----ELYDLKEEYDR 480

                          330       340
                   ....*....|....*....|.
gi 1012519614 1647 VSKQRDETALQLSVSQEQVKQ 1667
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1331-1767 2.67e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 2.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1331 ASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAAtselERKEHEQTDSEIKQLKEKQDVLQKLLKE 1410
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----LEQDIARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1411 KDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSM 1490
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1491 MLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLR 1570
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1571 DKEFRSNQELERLRNHLLESEDSYTREALAAEDREAK----LRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNV 1646
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGavavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1647 VSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEAN 1726
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1012519614 1727 AALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKL 1767
Cdd:COG1196    648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
440-852 3.16e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  440 LQMSLLKLNNEYEVI-KSTATRDISLDSELHDLRLNL---EAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKD 515
Cdd:COG4717     44 RAMLLERLEKEADELfKPQGRKPELNLKELKELEEELkeaEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  516 QLSKQQNEGDsiISKLKQDLNDEKKRVHQLEddkmditKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENL----VDQL 591
Cdd:COG4717    124 LLQLLPLYQE--LEALEAELAELPERLEELE-------ERLEELRELEEELEELEAELAELQEELEELLEQLslatEEEL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  592 NKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKER-----EAEVRNLKQNLSELEQLNEN 666
Cdd:COG4717    195 QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlllliAAALLALLGLGGSLLSLILT 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  667 LKKVAFDVK----MENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKmekgEIEAELCWAKKRLLEEANKYEKTI 742
Cdd:COG4717    275 IAGVLFLVLgllaLLFLLLAREKASLGKEAEELQALPALEELEEEELEELLA----ALGLPPDLSPEELLELLDRIEELQ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  743 EELSNARNLNTSALQLEHEHLIK--LNQKKDMEIAELKKNIEQMDTDHKETKDV------LSSSLEEQKQLTQLINKKEI 814
Cdd:COG4717    351 ELLREAEELEEELQLEELEQEIAalLAEAGVEDEEELRAALEQAEEYQELKEELeeleeqLEELLGELEELLEALDEEEL 430

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1012519614  815 F--IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDR 852
Cdd:COG4717    431 EeeLEELEEELEELEEELEELREELAELEAELEQLEEDGE 470
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 527-750 3.47e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  527 IISKLKQDLNDEKKrvhqleddkmdITKELDVQKEKliQSEVALNDLHLTKQKLEDKVENLVDQLNksqesnvsiqkenl 606
Cdd:PRK05771    58 ALDKLRSYLPKLNP-----------LREEKKKVSVK--SLEELIKDVEEELEKIEKEIKELEEEIS-------------- 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  607 ELKEHIRQNEEELSRIR-----NELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKL 681
Cdd:PRK05771   111 ELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVYVVVVVLKELS 190

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1012519614  682 vlacEDVRHQLEECLAGNNQLSLEK--NTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTI----EELSNARN 750
Cdd:PRK05771   191 ----DEVEEELKKLGFERLELEEEGtpSELIREIKEELEEIEKERESLLEELKELAKKYLEELlalyEYLEIELE 261
COG5022 COG5022
Myosin heavy chain [General function prediction only];
219-785 3.58e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  219 ELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDY-------EERIEELENLLQQggsgvIETDLSKIYEMQK 291
Cdd:COG5022    878 ELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLienlefkTELIARLKKLLNN-----IDLEEGPSIEYVK 952

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  292 TIQVLQIEKVESTKKMEQLE-------------------DKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEecenl 352
Cdd:COG5022    953 LPELNKLHEVESKLKETSEEyedllkkstilvregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEVAE----- 1027

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  353 klecsklQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMrlsSLNQDNSLAEDNLKLKMRIeVLEKEKSL 432
Cdd:COG5022   1028 -------LQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKAL---KLRRENSLLDDKQLYQLES-TENLLKTI 1096

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  433 LSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMIL 512
Cdd:COG5022   1097 NVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAA 1176

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  513 IKDQLSKQQNEGDsIISKLKQDLNDEKKRVHQLEDDKmdiTKELDVQKEKLIQSEVALNDLHLTKQKLED---------- 582
Cdd:COG5022   1177 LSEKRLYQSALYD-EKSKLSSSEVNDLKNELIALFSK---IFSGWPRGDKLKKLISEGWVPTEYSTSLKGfnnlnkkfdt 1252

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  583 ----KVENLVDQLNKSQESNVSIQKENLELKEHIRQNE--------EELSRIRNELMQSLNQDSNSNFKDTLLKEREAEV 650
Cdd:COG5022   1253 pasmSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLqyinvglfNALRTKASSLRWKSATEVNYNSEELDDWCREFEI 1332

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  651 RNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKmekgEIEAELCWAKKR 730
Cdd:COG5022   1333 SDVDEELEELIQAVKVLQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPKEILK----KIEALLIKQELQ 1408

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1012519614  731 L--LEEANKYEKTIEELSNARNLntsaLQLEHEHLIKlNQKKDMEIAEL-KKNIEQMD 785
Cdd:COG5022   1409 LslEGKDETEVHLSEIFSEEKSL----ISLDRNSIYK-EEVLSSLSALLtKEKIALLD 1461
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
212-662 4.08e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  212 KLQNIIKELKQNRsQEIDDHQHEMSVLQNAHQ-QKLTEISRRHREELSDYEERIEELENLLQQggsgvIETDLSKIYEMQ 290
Cdd:COG4717     96 ELEELEEELEELE-AELEELREELEKLEKLLQlLPLYQELEALEAELAELPERLEELEERLEE-----LRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  291 KTIQVLQIEKVESTKKM-EQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQsdt 369
Cdd:COG4717    170 AELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK--- 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 mtEKERILAQSASVEEVFRLQQALSDAENEIMRLsslnqdnslaednlkLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 449
Cdd:COG4717    247 --EARLLLLIAAALLALLGLGGSLLSLILTIAGV---------------LFLVLGLLALLFLLLAREKASLGKEAEELQA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  450 EYEvikSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEAtkhmilikdQLSKQQNEGDSIIS 529
Cdd:COG4717    310 LPA---LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL---------QLEELEQEIAALLA 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  530 KLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLiqsevalndlhltkQKLEDKVENLVDQLNKSQesnvsIQKENLELK 609
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQL--------------EELLGELEELLEALDEEE-----LEEELEELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1012519614  610 EHIRQNEEELSRIRNELmQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQ 662
Cdd:COG4717    439 EELEELEEELEELREEL-AELEAELEQLEEDGELAELLQELEELKAELRELAE 490
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1401-1762 4.96e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.80  E-value: 4.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1401 QDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQA 1480
Cdd:pfam07888   33 QNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1481 LQEtnmKFSMMLREKEFECHSMKEKALAFeQLLKEKEQGKTGELNQLLNAVKsmqektvvfqqerdQVMLALKQKQMENT 1560
Cdd:pfam07888  113 LSE---EKDALLAQRAAHEARIRELEEDI-KTLTQRVLERETELERMKERAK--------------KAGAQRKEEEAERK 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1561 ALQNEVQRLRDKEFRSNQELERLRNHLLESEDSytreALAAEDREAKLRKKVTVLEEKLVSSSNAME---------NASH 1631
Cdd:pfam07888  175 QLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ----VLQLQDTITTLTQKLTTAHRKEAENEALLEelrslqerlNASE 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1632 QAsvqVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLE----HFQQEEKAM-------------YSAEL 1694
Cdd:pfam07888  251 RK---VEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALRegraRWAQERETLqqsaeadkdriekLSAEL 327

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1012519614 1695 EKQKQLIAEWKKNAENLEGKVISLQEC-----------LDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDD 1762
Cdd:pfam07888  328 QRLEERLQEERMEREKLEVELGREKDCnrvqlsesrreLQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1204-1762 5.52e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1204 EELLQERDKLKQQVKKMEEWKQqvmttvqnmqhesaqLQEELHQLQAQVLVDSDNNskLQVDYTGLIQSYEQNETKLKNF 1283
Cdd:COG1196    196 GELERQLEPLERQAEKAERYRE---------------LKEELKELEAELLLLKLRE--LEAELEELEAELEELEAELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1284 GQELAQVQHSIGQLcntKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQE--LEELRKSLQEKDAT 1361
Cdd:COG1196    259 EAELAELEAELEEL---RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEelEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1362 IRTLQEnnhrlsdsIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQ 1441
Cdd:COG1196    336 EEELEE--------LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1442 AVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKfsmmLREKEFECHSMKEKALAFEQLLKEKEQGKT 1521
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE----LEEEEEALLELLAELLEEAALLEAALAELL 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1522 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMEntALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAA 1601
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR--GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1602 EDREAKLRKK-------VTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETAL-----------------Q 1657
Cdd:COG1196    562 AIEYLKAAKAgratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLgrtlvaarleaalrravT 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1658 LSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTE 1737
Cdd:COG1196    642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721

                          570       580
                   ....*....|....*....|....*
gi 1012519614 1738 QLDVKEEQIEELKRQNELRQEMLDD 1762
Cdd:COG1196    722 EEEALEEQLEAEREELLEELLEEEE 746
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1058-1767 5.90e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 5.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1058 QIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAME----REKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALI 1133
Cdd:TIGR00606  200 QKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREivksYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1134 KLQDENKKLSTRFESSGQ---DMFRETIQNLSRIIREK--------------DIEIDALSQKCQTLLAVLQTSSTGNEAG 1196
Cdd:TIGR00606  280 QMEKDNSELELKMEKVFQgtdEQLNDLYHNHQRTVREKerelvdcqreleklNKERRLLNQEKTELLVEQGRLQLQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1197 GVNSNQFEELLQ------ERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLI 1270
Cdd:TIGR00606  360 QEHIRARDSLIQslatrlELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1271 QSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQS-AECLRASKSEVLSESSELLQQELE 1349
Cdd:TIGR00606  440 RTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSlTETLKKEVKSLQNEKADLDRKLRK 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1350 ELRKsLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQL------KEKQDVLQKLLKEKDLLIKAKSD--- 1420
Cdd:TIGR00606  520 LDQE-MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpnkKQLEDWLHSKSKEINQTRDRLAKlnk 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1421 QLLSSNENFTNKVNENELLRQAVTNLKERIL------ILEMDIGKLKGENEKivetYRGKETEYQALQETNMKFSMMLRE 1494
Cdd:TIGR00606  599 ELASLEQNKNHINNELESKEEQLSSYEDKLFdvcgsqDEESDLERLKEEIEK----SSKQRAMLAGATAVYSQFITQLTD 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1495 KEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEF 1574
Cdd:TIGR00606  675 ENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQ 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1575 RSNQELERLRNHLLESEDSYtrEALAAEDREAK-LRKKVTVLEEKLVSSSNAMENASHQAS-VQVESLQEQLNVVSKQRD 1652
Cdd:TIGR00606  755 KVNRDIQRLKNDIEEQETLL--GTIMPEEESAKvCLTDVTIMERFQMELKDVERKIAQQAAkLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1653 ETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLiAEWKKNAENLEGKVISLQECL----DEANAA 1728
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNL-QRRQQFEEQLVELSTEVQSLIreikDAKEQD 911

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1012519614 1729 LDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKL 1767
Cdd:TIGR00606  912 SPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKV 950
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 446-629 6.29e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 6.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  446 KLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEI----EELDRQNQEATKHMILIKDQLSKQQ 521
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIdklqAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  522 NEGDSI------------------ISKLKQDLNDEKKRVHQLEDDKmditKELDVQKEKLiqsEVALNDLHLTKQKLEDK 583
Cdd:COG3883     97 RSGGSVsyldvllgsesfsdfldrLSALSKIADADADLLEELKADK----AELEAKKAEL---EAKLAELEALKAELEAA 169

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1012519614  584 VENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQS 629
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
46 PHA02562
endonuclease subunit; Provisional
 412-626 6.40e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 6.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  412 LAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISldsELHDLRLNLEAKEQELNQSISEket 491
Cdd:PHA02562   165 LSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIA---RKQNKYDELVEEAKTIKAEIEE--- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  492 LIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLK------------QDLNDEKKRVHQLEDDKMDITKEL--- 556
Cdd:PHA02562   239 LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKmyekggvcptctQQISEGPDRITKIKDKLKELQHSLekl 318

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  557 DVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNEL 626
Cdd:PHA02562   319 DTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDEL 388
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
47-705 6.48e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   47 ELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTsyrNQLQQKEVEISHLKARQIALQDQLLKLQSA 126
Cdd:COG4913    291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG---DRLEQLEREIERLERELEERERRRARLEAL 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  127 AQSVpsGAGVPATTAsssfaygishhpsafhdddmDFGDIIS-SQQEINRLSNEVSRLESEVghWRHIAQTSKAqgtdns 205
Cdd:COG4913    368 LAAL--GLPLPASAE--------------------EFAALRAeAAALLEALEEELEALEEAL--AEAEAALRDL------ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  206 dQSEICKLQNIIKELKQNRSQeIDDHQHEMsvlqnahqqkLTEIsrrhREELSDYEERIEELENLLQQGGS-----GVIE 280
Cdd:COG4913    418 -RRELRELEAEIASLERRKSN-IPARLLAL----------RDAL----AEALGLDEAELPFVGELIEVRPEeerwrGAIE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  281 T-----------------DLSKIYEMQKTIQVLQIEKVEST-KKMEQLEDKIKDINKKLSSAEND-RDILRRE------- 334
Cdd:COG4913    482 RvlggfaltllvppehyaAALRWVNRLHLRGRLVYERVRTGlPDPERPRLDPDSLAGKLDFKPHPfRAWLEAElgrrfdy 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  335 -----QEQLNVEKRQIMEECEnlklecsklqpsaVKQSDTMTEK--------ERILAQSAsveevfrlQQALSDAENEIm 401
Cdd:COG4913    562 vcvdsPEELRRHPRAITRAGQ-------------VKGNGTRHEKddrrrirsRYVLGFDN--------RAKLAALEAEL- 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  402 rlsslnqdNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMsLLKLNNEYEVIKSTATRDISLDSELHDLRLN---LEAK 478
Cdd:COG4913    620 --------AELEEELAEAEERLEALEAELDALQERREALQR-LAEYSWDEIDVASAEREIAELEAELERLDASsddLAAL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  479 EQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDE-KKRVHQLEDDKmdITKELD 557
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALlEERFAAALGDA--VERELR 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  558 VQKEKLIQSEVALndlhltKQKLEDKVENLVDQLNK---SQESNVSIQKENLE--LKEHIRQNEEELSRIRNELMQSLNQ 632
Cdd:COG4913    769 ENLEERIDALRAR------LNRAEEELERAMRAFNRewpAETADLDADLESLPeyLALLDRLEEDGLPEYEERFKELLNE 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  633 DSNsNFKDTLLKEREAEVRNLKQNlseLEQLNENLKKVAFDvkmENEKLVLACEDVRH--------QLEECLAGNNQLSL 704
Cdd:COG4913    843 NSI-EFVADLLSKLRRAIREIKER---IDPLNDSLKRIPFG---PGRYLRLEARPRPDpevrefrqELRAVTSGASLFDE 915


                   .
gi 1012519614  705 E 705
Cdd:COG4913    916 E 916
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1631-1771 6.70e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 6.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1631 HQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEkAMYSAELEKQKQLIAEWKKNAEN 1710
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1012519614 1711 LEGKVISLQECLDEANAALDsasRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLA 1771
Cdd:COG1196    314 LEERLEELEEELAELEEELE---ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371
bHLHzip_Myc cd11400
basic Helix-Loop-Helix-zipper (bHLHzip) domain found in the Myc family; The Myc family is a ...
 63-122 6.71e-03

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in the Myc family; The Myc family is a member of the bHLHzip family of transcription factors that play important roles in the control of normal cell proliferation, growth, survival and differentiation. All Myc isoforms contain two independently functioning polypeptide chain regions: N-terminal transactivating residues and a C-terminal bHLHzip segment. The bHLHzip family of bHLH transcription factors are characterized by a highly conserved N-terminal basic region that may bind DNA at a consensus hexanucleotide sequence known as the E-box (CANNTG) followed by HLH and leucine zipper motifs that may interact with other proteins to form homo- and heterodimers. Myc heterodimerizes with Max enabling specific binding to E-box DNA sequences in the promoters of target genes. The Myc proto-oncoprotein family includes at least five different functional members: c-, N-, L-, S- and B-Myc (which is lacking the bHLH domain).


Pssm-ID: 381406 [Multi-domain]  Cd Length: 80  Bit Score: 37.53  E-value: 6.71e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614   63 LRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLK 122
Cdd:cd11400     16 LKNSFEKLRDLVPELADNEKASKVVILKKATEYIKQLQQEEKKLEKEKDKLKARNEQLRK 75
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
370-656 6.87e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 6.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  370 MTEKERILAQSASVEEVF----RLQQALSDAENEIMRLSSLNQdnsLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLL 445
Cdd:COG4913    217 MLEEPDTFEAADALVEHFddleRAHEALEDAREQIELLEPIRE---LAERYAAARERLAELEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  446 KlnneyevikstatrdisldSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQnqeatkhmilikdqlsKQQNEGD 525
Cdd:COG4913    294 E-------------------AELEELRAELARLEAELERLEARLDALREELDELEAQ----------------IRGNGGD 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  526 siisklkqdlndekkRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQEsnvsiqken 605
Cdd:COG4913    339 ---------------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE--------- 394

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1012519614  606 lELKEHIRQNEEELSRIRNELMQSLNQdsnsnfkdtlLKEREAEVRNLKQN 656
Cdd:COG4913    395 -ALEEELEALEEALAEAEAALRDLRRE----------LRELEAEIASLERR 434
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1602-1770 7.48e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 7.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1602 EDREAKLRKKVTVLEEKLVS--SSNAMENASHQASV---QVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANL- 1675
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLllqQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1676 -----QMVLEHFQQ------EEKAMYS----------AELEKQKQLI-AEWKKNAENLEGKVISLQECLDEANAALDSAS 1733
Cdd:COG3206    261 qspviQQLRAQLAEleaelaELSARYTpnhpdvialrAQIAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQLE 340

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1012519614 1734 RLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSL 1770
Cdd:COG3206    341 ARLAELPELEAELRRLEREVEVARELYESLLQRLEEA 377
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 719-1281 8.08e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  719 EIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQkkdmEIAELKKNIEQMDTDHKETKDVLSSS 798
Cdd:pfam15921  321 DLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ----ESGNLDDQLQKLLADLHKREKELSLE 396

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  799 LEEQKQLTQLINKKEIFIEKLKErssklqeELDKYSQALRKNEILRQTIeeKDRSLGSMKEEnnhlqeelerlreeqsRT 878
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRR-------ELDDRNMEVQRLEALLKAM--KSECQGQMERQ----------------MA 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  879 APVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNA------T 952
Cdd:pfam15921  452 AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSrvdlklQ 531

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614  953 HTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVqslnIENGSEKHDLSKAETERLVKGIKERELEI- 1031
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQL----VGQHGRTAGAMQVEKAQLEKEINDRRLELq 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1032 --KLLNEKNISLTKQIDQlskdevgkltqiiQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTR 1109
Cdd:pfam15921  608 efKILKDKKDAKIRELEA-------------RVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSE 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1110 ENSHLKTEYH---KMMDIVAAK-----EAALIKLQDENKKLSTRFESSGQDMfrETIQNLSRIIREKDIEIDALSQKCQT 1181
Cdd:pfam15921  675 DYEVLKRNFRnksEEMETTTNKlkmqlKSAQSELEQTRNTLKSMEGSDGHAM--KVAMGMQKQITAKRGQIDALQSKIQF 752

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012519614 1182 LlavlqtsstgnEAGGVNSNQFEELL-QERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQaqvlVDSDNNS 1260
Cdd:pfam15921  753 L-----------EEAMTNANKEKHFLkEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME----VALDKAS 817

                          570       580
                   ....*....|....*....|.
gi 1012519614 1261 KLQVDYTGLIQSYEQNETKLK 1281
Cdd:pfam15921  818 LQFAECQDIIQRQEQESVRLK 838
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH