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rhomboid-related protein 4 [Homo sapiens]
rhomboid family intramembrane serine protease( domain architecture ID 10002186)
rhomboid family intramembrane serine protease is a membrane-bound protein that catalyzes regulated intramembrane proteolysis, resulting in the release of functional polypeptides from their membrane anchor
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
26-206 | 1.17e-15 | ||||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; : Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 73.74 E-value: 1.17e-15
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Name | Accession | Description | Interval | E-value | ||||
GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
26-206 | 1.17e-15 | ||||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 73.74 E-value: 1.17e-15
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Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
65-206 | 6.03e-15 | ||||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 70.71 E-value: 6.03e-15
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rhom_GG_sort | TIGR03902 | rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like ... |
64-150 | 2.12e-03 | ||||
rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like intramembrane serine protease. Its species distribution closely matches model TIGR03501, GlyGly-CTERM, which describes a protein targeting domain analogous to LPXTG and PEP-CTERM. In a number of species (Ralstonia eutropha ,R. metallidurans, R. solanacearum, Marinobacter aquaeolei, etc) with just one GlyGly-CTERM protein (i.e., a dedicated system), the rhombosortase and GlyGly-CTERM genes are adjacent. Pssm-ID: 274845 Cd Length: 154 Bit Score: 37.94 E-value: 2.12e-03
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Name | Accession | Description | Interval | E-value | ||||
GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
26-206 | 1.17e-15 | ||||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 73.74 E-value: 1.17e-15
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Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
65-206 | 6.03e-15 | ||||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 70.71 E-value: 6.03e-15
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rhom_GG_sort | TIGR03902 | rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like ... |
64-150 | 2.12e-03 | ||||
rhomboid family GlyGly-CTERM serine protease; This model describes a rhomboid-like intramembrane serine protease. Its species distribution closely matches model TIGR03501, GlyGly-CTERM, which describes a protein targeting domain analogous to LPXTG and PEP-CTERM. In a number of species (Ralstonia eutropha ,R. metallidurans, R. solanacearum, Marinobacter aquaeolei, etc) with just one GlyGly-CTERM protein (i.e., a dedicated system), the rhombosortase and GlyGly-CTERM genes are adjacent. Pssm-ID: 274845 Cd Length: 154 Bit Score: 37.94 E-value: 2.12e-03
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Blast search parameters | ||||
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