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Conserved domains on  [gi|1238789372|ref|NP_001341919|]
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interleukin-4 isoform 3 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IL4 super family cl11518
Interleukin 4;
1-77 6.60e-18

Interleukin 4;


The actual alignment was detected with superfamily member smart00190:

Pssm-ID: 472207  Cd Length: 138  Bit Score: 74.41  E-value: 6.60e-18
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238789372    1 MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKT-LCTELTVTDIFAASKQhaclptSRHTGTICR 77
Cdd:smart00190   1 MGLTPQLVPALLCLLGCTGNGPHGHSCDITLREIIETLNNVTQKGTnLCTEMMVPDVLAATKN------TTEKELFCR 72
 
Name Accession Description Interval E-value
IL4_13 smart00190
Interleukins 4 and 13; Interleukins-4 and -13 are cytokines involved in inflammatory and ...
 1-77 6.60e-18

Interleukins 4 and 13; Interleukins-4 and -13 are cytokines involved in inflammatory and immune responses. IL-4 stimulates B and T cells.


Pssm-ID: 197564  Cd Length: 138  Bit Score: 74.41  E-value: 6.60e-18
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238789372    1 MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKT-LCTELTVTDIFAASKQhaclptSRHTGTICR 77
Cdd:smart00190   1 MGLTPQLVPALLCLLGCTGNGPHGHSCDITLREIIETLNNVTQKGTnLCTEMMVPDVLAATKN------TTEKELFCR 72
IL4 pfam00727
Interleukin 4;
26-61 4.73e-16

Interleukin 4;


Pssm-ID: 459916  Cd Length: 116  Bit Score: 69.06  E-value: 4.73e-16
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1238789372  26 KCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASK 61
Cdd:pfam00727   1 KCDITLQEIIKTLNILTERKTPCTELTVADVFAAPK 36
 
Name Accession Description Interval E-value
IL4_13 smart00190
Interleukins 4 and 13; Interleukins-4 and -13 are cytokines involved in inflammatory and ...
 1-77 6.60e-18

Interleukins 4 and 13; Interleukins-4 and -13 are cytokines involved in inflammatory and immune responses. IL-4 stimulates B and T cells.


Pssm-ID: 197564  Cd Length: 138  Bit Score: 74.41  E-value: 6.60e-18
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1238789372    1 MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKT-LCTELTVTDIFAASKQhaclptSRHTGTICR 77
Cdd:smart00190   1 MGLTPQLVPALLCLLGCTGNGPHGHSCDITLREIIETLNNVTQKGTnLCTEMMVPDVLAATKN------TTEKELFCR 72
IL4 pfam00727
Interleukin 4;
26-61 4.73e-16

Interleukin 4;


Pssm-ID: 459916  Cd Length: 116  Bit Score: 69.06  E-value: 4.73e-16
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1238789372  26 KCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASK 61
Cdd:pfam00727   1 KCDITLQEIIKTLNILTERKTPCTELTVADVFAAPK 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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