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transportin-3 isoform 9 [Homo sapiens]
exportin/importin beta family protein( domain architecture ID 10658450)
exportin/importin beta family protein such as human exportin-T, which mediates the nuclear export of aminoacylated tRNAs or transportin-3 (importin), which transports target proteins into the nucleus
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Xpo1 | pfam08389 | Exportin 1-like protein; The sequences featured in this family are similar to a region close ... |
121-249 | 1.48e-20 | |||
Exportin 1-like protein; The sequences featured in this family are similar to a region close to the N-terminus of yeast exportin 1 (Xpo1, Crm1). This region is found just C-terminal to an importin-beta N-terminal domain (pfam03810) in many members of this family. Exportin 1 is a nuclear export receptor that interacts with leucine-rich nuclear export signal (NES) sequences, and Ran-GTP, and is involved in translocation of proteins out of the nucleus. : Pssm-ID: 462459 Cd Length: 147 Bit Score: 88.82 E-value: 1.48e-20
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IBN_N | smart00913 | Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ... |
33-96 | 3.60e-08 | |||
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport. : Pssm-ID: 197981 [Multi-domain] Cd Length: 67 Bit Score: 50.70 E-value: 3.60e-08
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Name | Accession | Description | Interval | E-value | |||
Xpo1 | pfam08389 | Exportin 1-like protein; The sequences featured in this family are similar to a region close ... |
121-249 | 1.48e-20 | |||
Exportin 1-like protein; The sequences featured in this family are similar to a region close to the N-terminus of yeast exportin 1 (Xpo1, Crm1). This region is found just C-terminal to an importin-beta N-terminal domain (pfam03810) in many members of this family. Exportin 1 is a nuclear export receptor that interacts with leucine-rich nuclear export signal (NES) sequences, and Ran-GTP, and is involved in translocation of proteins out of the nucleus. Pssm-ID: 462459 Cd Length: 147 Bit Score: 88.82 E-value: 1.48e-20
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IBN_N | smart00913 | Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ... |
33-96 | 3.60e-08 | |||
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport. Pssm-ID: 197981 [Multi-domain] Cd Length: 67 Bit Score: 50.70 E-value: 3.60e-08
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Name | Accession | Description | Interval | E-value | |||
Xpo1 | pfam08389 | Exportin 1-like protein; The sequences featured in this family are similar to a region close ... |
121-249 | 1.48e-20 | |||
Exportin 1-like protein; The sequences featured in this family are similar to a region close to the N-terminus of yeast exportin 1 (Xpo1, Crm1). This region is found just C-terminal to an importin-beta N-terminal domain (pfam03810) in many members of this family. Exportin 1 is a nuclear export receptor that interacts with leucine-rich nuclear export signal (NES) sequences, and Ran-GTP, and is involved in translocation of proteins out of the nucleus. Pssm-ID: 462459 Cd Length: 147 Bit Score: 88.82 E-value: 1.48e-20
|
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IBN_N | smart00913 | Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ... |
33-96 | 3.60e-08 | |||
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport. Pssm-ID: 197981 [Multi-domain] Cd Length: 67 Bit Score: 50.70 E-value: 3.60e-08
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Blast search parameters | ||||
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