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Conserved domains on  [gi|2451822004|ref|NP_001404410|]
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fructose-1,6-bisphosphatase, chloroplastic [Oryza sativa Japonica Group]

Protein Classification

class 1 fructose-bisphosphatase( domain architecture ID 10791396)

class 1 chloroplastic fructose-bisphosphatase catalyzes the conversion of D-fructose 1,6-bisphosphate to D-fructose 6-phosphate in gluconeogenesis and the Calvin cycle, which are both anabolic pathways

EC:  3.1.3.11
Gene Ontology:  GO:0042132|GO:0000287
SCOP:  4002766

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02542 PLN02542
fructose-1,6-bisphosphatase
3-406 0e+00

fructose-1,6-bisphosphatase


:

Pssm-ID: 215298 [Multi-domain]  Cd Length: 412  Bit Score: 787.53  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004   3 AAATTSSHLLLLSRQQAAASLQCGL---------SFRRQPGRlAGGSSAPSVRCMAAVDTASAPAATEASKKSSYEITTL 73
Cdd:PLN02542    1 AATTTSSHLLLSSSRSVAPASQCQLssfdsltlnSFPRSPGS-KKHHSAAGVRCAAAAAAAAATASPAATKKSGYEIQTL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  74 TTWLLKQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGV 153
Cdd:PLN02542   80 TTWLLKQEQAGVIDAELTIVLSSISMACKQIASLVQRAGISNLTGVQGAVNIQGEDQKKLDVISNEVFSNCLRSSGRTGI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 154 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADDQNLDQVEQRCIVSVCQPGSNL 233
Cdd:PLN02542  160 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIGDDSTLDSVEQRCIVNVCQPGSNL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 234 LAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEPGPSGKP 313
Cdd:PLN02542  240 LAAGYCMYSSSVIFVLTIGTGVFSFTLDPMYGEFVLTQENIQIPKAGKIYSFNEGNYQLWDDKLKKYIDDLKDPGPSGKP 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 314 YSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIG 393
Cdd:PLN02542  320 YSARYIGSLVGDFHRTLLYGGIYGYPRDKKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQRVPLYIG 399
                         410
                  ....*....|...
gi 2451822004 394 SVEEVEKVEKFLA 406
Cdd:PLN02542  400 SVEEVEKLEKYLA 412
 
Name Accession Description Interval E-value
PLN02542 PLN02542
fructose-1,6-bisphosphatase
3-406 0e+00

fructose-1,6-bisphosphatase


Pssm-ID: 215298 [Multi-domain]  Cd Length: 412  Bit Score: 787.53  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004   3 AAATTSSHLLLLSRQQAAASLQCGL---------SFRRQPGRlAGGSSAPSVRCMAAVDTASAPAATEASKKSSYEITTL 73
Cdd:PLN02542    1 AATTTSSHLLLSSSRSVAPASQCQLssfdsltlnSFPRSPGS-KKHHSAAGVRCAAAAAAAAATASPAATKKSGYEIQTL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  74 TTWLLKQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGV 153
Cdd:PLN02542   80 TTWLLKQEQAGVIDAELTIVLSSISMACKQIASLVQRAGISNLTGVQGAVNIQGEDQKKLDVISNEVFSNCLRSSGRTGI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 154 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADDQNLDQVEQRCIVSVCQPGSNL 233
Cdd:PLN02542  160 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIGDDSTLDSVEQRCIVNVCQPGSNL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 234 LAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEPGPSGKP 313
Cdd:PLN02542  240 LAAGYCMYSSSVIFVLTIGTGVFSFTLDPMYGEFVLTQENIQIPKAGKIYSFNEGNYQLWDDKLKKYIDDLKDPGPSGKP 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 314 YSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIG 393
Cdd:PLN02542  320 YSARYIGSLVGDFHRTLLYGGIYGYPRDKKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQRVPLYIG 399
                         410
                  ....*....|...
gi 2451822004 394 SVEEVEKVEKFLA 406
Cdd:PLN02542  400 SVEEVEKLEKYLA 412
FBPase cd00354
Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1, ...
77-405 0e+00

Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1,7-biphosphatases that play a role in pentose phosphate pathway (Calvin cycle).


Pssm-ID: 238214 [Multi-domain]  Cd Length: 315  Bit Score: 518.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  77 LLKQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIAS 156
Cdd:cd00354     1 LLEQLRKGAATGDLTDLLSSLALACKEISRAVRRAGLAGLLGLAGSVNVQGDEQKKLDVLANDIFIEALKSSGVVAVLAS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 157 EEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADdqnldqveqrcivsVCQPGSNLLAA 236
Cdd:cd00354    81 EEEEEPVPVEESKDGKYLVAFDPLDGSSNIDANVSVGTIFSIYPGPSGADATEKD--------------FLQPGRNQVAA 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 237 GYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEPGPSGKPYSA 316
Cdd:cd00354   147 GYALYGPSTMLVLTLGQGVHGFTLDPSLGEFILTHPNVKIPKKGKIYSINEGNYRYWDEPVKKYIDDCKAGEDGGKPYNL 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 317 RYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIGSVE 396
Cdd:cd00354   227 RYIGSMVADVHRILVRGGIFLYPADKKSPKGKLRLLYEANPMAFLVEQAGGKATDGKERILDIVPTSLHQRVPVILGSKE 306

                  ....*....
gi 2451822004 397 EVEKVEKFL 405
Cdd:cd00354   307 EVERVEEYL 315
Fbp COG0158
Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1, ...
71-406 2.94e-169

Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1,6-bisphosphatase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 439928 [Multi-domain]  Cd Length: 338  Bit Score: 476.91  E-value: 2.94e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  71 TTLTTWLL-KQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSG 149
Cdd:COG0158     5 TTLTQFLIeQQRRFPGATGELSALLNAIALAAKIISREVNKGGLAGILGAAGSENVQGETQKKLDVIANEIFIEALEWGG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 150 RTGVIASEEEDVPVAVEESY-SGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADDqnldqveqrcivsVCQ 228
Cdd:COG0158    85 HVAAMASEEMDDPIPIPEQYpRGKYLVLFDPLDGSSNIDVNVSVGTIFSILRRPSGGGPVTEED-------------FLQ 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 229 PGSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKE-- 306
Cdd:COG0158   152 PGSEQVAAGYVLYGPSTMLVLTTGNGVHGFTLDPSIGEFLLTHPNMRIPEDTKEYAINESNYRHWEPPVRRYIDECLAgk 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 307 PGPSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQK--SKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEI 384
Cdd:COG0158   232 EGPRGRDFNMRWIGSLVADVHRILLRGGIFLYPADSRdgYPPGKLRLLYEANPMAFLVEQAGGAATDGRQRILDIVPTSL 311
                         330       340
                  ....*....|....*....|..
gi 2451822004 385 HQRVPLYIGSVEEVEKVEKFLA 406
Cdd:COG0158   312 HQRVPLILGSKEEVERVERYHA 333
FBPase_C pfam18913
Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of ...
280-406 4.17e-64

Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of Fructose-1-6-bisphosphatase enzymes. According to ECOD this domain has a Rossmann-like fold.


Pssm-ID: 436826 [Multi-domain]  Cd Length: 125  Bit Score: 201.31  E-value: 4.17e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 280 GKIYAFNEGNYALWDDKLKSYMDSLKepgpSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMS 359
Cdd:pfam18913   3 GKIYAINEGNARFWNAPYRAYIDDLV----SGKGYTLRYIGSMVADVHRILLKGGIFLYPADRRSPYGKLRLLYECAPLA 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2451822004 360 FIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIGSVEEVEKVEKFLA 406
Cdd:pfam18913  79 FLIEQAGGKASDGTQRILDIVPDSLHQRTPIFLGSRDEVARVEAYLK 125
 
Name Accession Description Interval E-value
PLN02542 PLN02542
fructose-1,6-bisphosphatase
3-406 0e+00

fructose-1,6-bisphosphatase


Pssm-ID: 215298 [Multi-domain]  Cd Length: 412  Bit Score: 787.53  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004   3 AAATTSSHLLLLSRQQAAASLQCGL---------SFRRQPGRlAGGSSAPSVRCMAAVDTASAPAATEASKKSSYEITTL 73
Cdd:PLN02542    1 AATTTSSHLLLSSSRSVAPASQCQLssfdsltlnSFPRSPGS-KKHHSAAGVRCAAAAAAAAATASPAATKKSGYEIQTL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  74 TTWLLKQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGV 153
Cdd:PLN02542   80 TTWLLKQEQAGVIDAELTIVLSSISMACKQIASLVQRAGISNLTGVQGAVNIQGEDQKKLDVISNEVFSNCLRSSGRTGI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 154 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADDQNLDQVEQRCIVSVCQPGSNL 233
Cdd:PLN02542  160 IASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIGDDSTLDSVEQRCIVNVCQPGSNL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 234 LAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEPGPSGKP 313
Cdd:PLN02542  240 LAAGYCMYSSSVIFVLTIGTGVFSFTLDPMYGEFVLTQENIQIPKAGKIYSFNEGNYQLWDDKLKKYIDDLKDPGPSGKP 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 314 YSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIG 393
Cdd:PLN02542  320 YSARYIGSLVGDFHRTLLYGGIYGYPRDKKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQRVPLYIG 399
                         410
                  ....*....|...
gi 2451822004 394 SVEEVEKVEKFLA 406
Cdd:PLN02542  400 SVEEVEKLEKYLA 412
FBPase cd00354
Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1, ...
77-405 0e+00

Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1,7-biphosphatases that play a role in pentose phosphate pathway (Calvin cycle).


Pssm-ID: 238214 [Multi-domain]  Cd Length: 315  Bit Score: 518.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  77 LLKQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIAS 156
Cdd:cd00354     1 LLEQLRKGAATGDLTDLLSSLALACKEISRAVRRAGLAGLLGLAGSVNVQGDEQKKLDVLANDIFIEALKSSGVVAVLAS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 157 EEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADdqnldqveqrcivsVCQPGSNLLAA 236
Cdd:cd00354    81 EEEEEPVPVEESKDGKYLVAFDPLDGSSNIDANVSVGTIFSIYPGPSGADATEKD--------------FLQPGRNQVAA 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 237 GYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEPGPSGKPYSA 316
Cdd:cd00354   147 GYALYGPSTMLVLTLGQGVHGFTLDPSLGEFILTHPNVKIPKKGKIYSINEGNYRYWDEPVKKYIDDCKAGEDGGKPYNL 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 317 RYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIGSVE 396
Cdd:cd00354   227 RYIGSMVADVHRILVRGGIFLYPADKKSPKGKLRLLYEANPMAFLVEQAGGKATDGKERILDIVPTSLHQRVPVILGSKE 306

                  ....*....
gi 2451822004 397 EVEKVEKFL 405
Cdd:cd00354   307 EVERVEEYL 315
Fbp COG0158
Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1, ...
71-406 2.94e-169

Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Fructose-1,6-bisphosphatase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 439928 [Multi-domain]  Cd Length: 338  Bit Score: 476.91  E-value: 2.94e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  71 TTLTTWLL-KQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSG 149
Cdd:COG0158     5 TTLTQFLIeQQRRFPGATGELSALLNAIALAAKIISREVNKGGLAGILGAAGSENVQGETQKKLDVIANEIFIEALEWGG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 150 RTGVIASEEEDVPVAVEESY-SGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADDqnldqveqrcivsVCQ 228
Cdd:COG0158    85 HVAAMASEEMDDPIPIPEQYpRGKYLVLFDPLDGSSNIDVNVSVGTIFSILRRPSGGGPVTEED-------------FLQ 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 229 PGSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKE-- 306
Cdd:COG0158   152 PGSEQVAAGYVLYGPSTMLVLTTGNGVHGFTLDPSIGEFLLTHPNMRIPEDTKEYAINESNYRHWEPPVRRYIDECLAgk 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 307 PGPSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQK--SKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEI 384
Cdd:COG0158   232 EGPRGRDFNMRWIGSLVADVHRILLRGGIFLYPADSRdgYPPGKLRLLYEANPMAFLVEQAGGAATDGRQRILDIVPTSL 311
                         330       340
                  ....*....|....*....|..
gi 2451822004 385 HQRVPLYIGSVEEVEKVEKFLA 406
Cdd:COG0158   312 HQRVPLILGSKEEVERVERYHA 333
PRK09293 PRK09293
class 1 fructose-bisphosphatase;
71-406 5.54e-154

class 1 fructose-bisphosphatase;


Pssm-ID: 236458 [Multi-domain]  Cd Length: 327  Bit Score: 437.74  E-value: 5.54e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  71 TTLTTWLL-KQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSG 149
Cdd:PRK09293    3 KTLGEFLVeQQREFPHATGELTALISAIALAAKIISRAINKGGLADILGAAGTENVQGETQKKLDVFANEILIEALKARG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 150 RTGVIASEEEDVPVAVEESYsGNYIVVFDPLDGSSNIDAAVSTGSIFGIYspndECLADIADDQNLDQveqrcivsvcqP 229
Cdd:PRK09293   83 HVAGLASEEEDEIVPIPENE-GKYLVAYDPLDGSSNIDVNVSVGTIFSIY----RAPVGTPTEEDFLQ-----------P 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 230 GSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKE-PG 308
Cdd:PRK09293  147 GNNQVAAGYVLYGPSTMLVLTTGDGVHGFTLDPSLGEFVLTHENIRIPEDGKEYAINEGNQRHWEPGVKKYIELLAGkDG 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 309 PSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQRV 388
Cdd:PRK09293  227 PRGRPYNMRYIGSMVADVHRILLKGGIFLYPADEPYPNGKLRLLYEANPMAFLVEQAGGAASDGKQRILDIEPESLHQRV 306
                         330
                  ....*....|....*...
gi 2451822004 389 PLYIGSVEEVEKVEKFLA 406
Cdd:PRK09293  307 PLFLGSKEEVERVEEYHA 324
PLN02262 PLN02262
fructose-1,6-bisphosphatase
69-406 1.03e-146

fructose-1,6-bisphosphatase


Pssm-ID: 215147 [Multi-domain]  Cd Length: 340  Bit Score: 419.98  E-value: 1.03e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  69 EITTLTTWLL-KQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKS 147
Cdd:PLN02262   11 DLMTITRFVLnEQSKHPEARGDLTILLSHIVLGCKFVCSAVNKAGLAKLIGLAGETNVQGEEQKKLDVLSNDVFIKALVS 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 148 SGRTGVIASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLADIADdqnldqveqrcivsVC 227
Cdd:PLN02262   91 SGRTNVLVSEEDEEAIFVEPSKRGRYCVVFDPLDGSSNIDCGVSIGTIFGIYMLKDGGEGTVED--------------VL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 228 QPGSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNEGNYALWDDKLKSYMDSLKEP 307
Cdd:PLN02262  157 QPGKEMVAAGYCMYGSSCTLVLSTGGGVNGFTLDPSLGEFILTHPDIKIPKKGKIYSVNEGNAKNWDGPTAKYVEKCKFP 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 308 GPSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIMPTEIHQR 387
Cdd:PLN02262  237 KDGSSPKSLRYIGSMVADVHRTLLYGGIFLYPADKKSPNGKLRVLYEVFPMSFLVEQAGGQAFTGKQRALDLVPTKIHER 316
                         330
                  ....*....|....*....
gi 2451822004 388 VPLYIGSVEEVEKVEKFLA 406
Cdd:PLN02262  317 SPIFLGSYDDVEEIKALYA 335
PLN02628 PLN02628
fructose-1,6-bisphosphatase family protein
54-404 1.67e-110

fructose-1,6-bisphosphatase family protein


Pssm-ID: 215337 [Multi-domain]  Cd Length: 351  Bit Score: 328.29  E-value: 1.67e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  54 ASAPAATEASKKSSYEITTLTtwLLKQEQAGtIDGEMTIVLASISTACKQIASLVQRAPISNLT----GVQGAVNVQGED 129
Cdd:PLN02628    2 ASAPPLYTAARGAEGVCTLME--FLGTEGSN-VGDDLVVLMAHIQAACKRIAALLASPFNSELGktssGASGASGSGRDA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 130 QKKLDVVSNEVFSNCLKSSGRTGVIASEEEDVPVAVEESysGNYIVVFDPLDGSSNIDAAVSTGSIFGIYSPNDEcladi 209
Cdd:PLN02628   79 PKPLDIVSNEIILSSLRNSGKVAVMASEEDDAPIWIGDD--GPYVVVFDPLDGSRNIDASIPTGTIFGIYNRLVE----- 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 210 addqnLDQ--VEQRCIVSVCQPGSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQEKVQIPKAGKIYAFNE 287
Cdd:PLN02628  152 -----ADHlpVEEKAQLNVLQRGSRLVAAGYVLYSSATILCISFGSGTHGFTLDHSTGEFVLTHPDIKIPERGQIYSVND 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 288 GNYALWDDKLKSYMDSLKE-PGPSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQkskngkLRLLYECAPMSFIVEQAG 366
Cdd:PLN02628  227 ARYFDWPEGLRKYIDTVRQgKGQYPKKYSARYICSLVADLHRTILYGGIAMNPRSH------LRLVYEANPLSFLVEQAG 300
                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2451822004 367 GKGSDGHQRILDIMPTEIHQRVPLYIGSVEEVEKVEKF 404
Cdd:PLN02628  301 GRGSDGKRRILSIQPVKLHQRLPLFLGSSEDVLELESY 338
FBPase_C pfam18913
Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of ...
280-406 4.17e-64

Fructose-1-6-bisphosphatase, C-terminal domain; This entry represents the C-terminal domain of Fructose-1-6-bisphosphatase enzymes. According to ECOD this domain has a Rossmann-like fold.


Pssm-ID: 436826 [Multi-domain]  Cd Length: 125  Bit Score: 201.31  E-value: 4.17e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 280 GKIYAFNEGNYALWDDKLKSYMDSLKepgpSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDQKSKNGKLRLLYECAPMS 359
Cdd:pfam18913   3 GKIYAINEGNARFWNAPYRAYIDDLV----SGKGYTLRYIGSMVADVHRILLKGGIFLYPADRRSPYGKLRLLYECAPLA 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2451822004 360 FIVEQAGGKGSDGHQRILDIMPTEIHQRVPLYIGSVEEVEKVEKFLA 406
Cdd:pfam18913  79 FLIEQAGGKASDGTQRILDIVPDSLHQRTPIFLGSRDEVARVEAYLK 125
FBPase pfam00316
Fructose-1-6-bisphosphatase, N-terminal domain; This family represents the N-terminus of this ...
72-272 9.32e-63

Fructose-1-6-bisphosphatase, N-terminal domain; This family represents the N-terminus of this protein family.


Pssm-ID: 425601  Cd Length: 191  Bit Score: 199.99  E-value: 9.32e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  72 TLTTWLL-KQEQAGTIDGEMTIVLASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGR 150
Cdd:pfam00316   2 TLTRFIIeQQHEFPNATGELTTLLSAIQLAAKFISRDIRKAGLVNLLGLAGAENVQGDQQKKLDVLADELLKNALKASGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 151 TGVIASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIY---SPNDEcLADIADdqnldqveqrcivsVC 227
Cdd:pfam00316  82 VKVLVSEEEEELIVFEPPKRGKYVVCFDPLDGSSNIDVNVSVGTIFSIYrrvSPTDS-PTTIED--------------VL 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2451822004 228 QPGSNLLAAGYCMYSSSVIFVLTIGTGVYVFTLDPMYGEFVLTQE 272
Cdd:pfam00316 147 QPGNEQVAAGYAMYGSSTMLVLTTGCGVHGFTLDPSLGEFILTHE 191
PLN02462 PLN02462
sedoheptulose-1,7-bisphosphatase
85-405 5.08e-44

sedoheptulose-1,7-bisphosphatase


Pssm-ID: 215256 [Multi-domain]  Cd Length: 304  Bit Score: 155.27  E-value: 5.08e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  85 TIDGEMTIVLASISTACKQIASLVQRApisnLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIASEEEDVPVA 164
Cdd:PLN02462   10 TPDKKLRRLIMCMGEACRTIAFKVRTA----SCTGTACVNSFGDEQLAVDMLADKLLFEALKYSHVCKYACSEEVPEVQD 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 165 VEESYSGNYIVVFDPLDGSSNIDAAVSTGSIFGIYsPNDECLADIADDQnldqveqrcivsvcqpgsnlLAAGYCMYS-- 242
Cdd:PLN02462   86 MGGPVEGGFSVAFDPLDGSSIVDTNFAVGTIFGVW-PGDKLTGVTGRDQ--------------------VAAAMGIYGpr 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 243 SSVIFVLTIGTGVYVFTLDPmYGEFVLTQEKVQIpKAGKIyaFNEGNY-ALWD----DKLKSYMDSLKepgpsgkpYSAR 317
Cdd:PLN02462  145 TTYVVALKDGPGTHEFLLLD-DGKWQHVKETTEI-GEGKI--FSPGNLrATFDnpgyEKLINYYVSEK--------YTLR 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 318 YIGSLVGD-FHRTLLYGGIYGYPRDQKSKnGKLRLLYECAPMSFIVEQAGGKGSDGHQR--ILDIMPTEIHQRVPLYIGS 394
Cdd:PLN02462  213 YTGGMVPDvYQIIVKEKGVFTNVTSPKSK-AKLRLLFEVAPLGLLVEKAGGKSSDGVQGgsVLDKQINNLDQRTQVAYGS 291
                         330
                  ....*....|.
gi 2451822004 395 VEEVEKVEKFL 405
Cdd:PLN02462  292 KNEVIRFEETL 302
FIG cd01636
FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with ...
94-200 2.43e-10

FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in gluconeogenesis. Inositol-monophosphatases and inositol polyphosphatases play vital roles in eukaryotic signalling, as they participate in metabolizing the messenger molecule Inositol-1,4,5-triphosphate. Many of these enzymes are inhibited by Li+.


Pssm-ID: 238814 [Multi-domain]  Cd Length: 184  Bit Score: 59.33  E-value: 2.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004  94 LASISTACKQIASLVQRAPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIASeEEDVPVAVEESYSGNY 173
Cdd:cd01636     1 LEELCRVAKEAGLAILKAFGRELSGKVKITKSDNDPVTTADVAAETLIRNMLKSSFPDVKIVG-EESGVAEEVMGRRDEY 79
                          90       100
                  ....*....|....*....|....*...
gi 2451822004 174 IVVFDPLDGSSNIDAA-VSTGSIFGIYS 200
Cdd:cd01636    80 TWVIDPIDGTKNFINGlPFVAVVIAVYV 107
Arch_FBPase_2 cd01642
Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. ...
100-185 4.16e-05

Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. These are Mg++ dependent phosphatases. Members in this family may have fructose-1,6-bisphosphatase and/or inositol-monophosphatase activity. Fructose-1,6-bisphosphatase catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway.


Pssm-ID: 238820 [Multi-domain]  Cd Length: 244  Bit Score: 44.75  E-value: 4.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 100 ACKQIASLVQraPISNLTGVQGAVNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIASEEEDVpVAVEesySGNYIVVFDP 179
Cdd:cd01642     8 ITKEIILLLN--EKNRQGLVKLIRGAGGDVTRVADLKAEEIILKLLREEGVFGQIISEESGE-IRKG---SGEYIAVLDP 81

                  ....*.
gi 2451822004 180 LDGSSN 185
Cdd:cd01642    82 LDGSTN 87
Arch_FBPase_1 cd01515
Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family ...
101-185 8.84e-05

Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family (FBPase class IV). These are Mg++ dependent phosphatases. Members in this family may have both fructose-1,6-bisphosphatase and inositol-monophosphatase activity. In hyperthermophilic archaea, inositol monophosphatase is thought to play a role in the biosynthesis of di-myo-inositol-1,1'-phosphate, an osmolyte unique to hyperthermophiles.


Pssm-ID: 238773 [Multi-domain]  Cd Length: 257  Bit Score: 43.91  E-value: 8.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 101 CKQIASLVQRApISNLTGVQGAVNV-----QGEDQKKLDVVSNEVFSNCLKSSGRTGVIaSEEedVPVAVEESYSGnYIV 175
Cdd:cd01515     5 ARNIAKEIEKA-IKPLFGTEDASEVvkigaDGTPTKLIDKVAEDAAIEILKKLGSVNIV-SEE--IGVIDNGDEPE-YTV 79
                          90
                  ....*....|
gi 2451822004 176 VFDPLDGSSN 185
Cdd:cd01515    80 VLDPLDGTYN 89
PRK12676 PRK12676
bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase;
100-185 2.56e-04

bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase;


Pssm-ID: 183673 [Multi-domain]  Cd Length: 263  Bit Score: 42.20  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2451822004 100 ACKQIASLVQRApISNLTGVQGA-----VNVQGEDQKKLDVVSNEVFSNCLKSSGRTGVIASEEEDVPVAVEESYsgnyI 174
Cdd:PRK12676    9 ICDDMAKEVEKA-IMPLFGTPDAgetvgMGADGTPTKLIDKVAEDIILEVLKPLGRCVNIISEELGEIVGNGPEY----T 83
                          90
                  ....*....|.
gi 2451822004 175 VVFDPLDGSSN 185
Cdd:PRK12676   84 VVLDPLDGTYN 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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