|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
10-319 |
4.28e-116 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 338.39 E-value: 4.28e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 10 PWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLYGpELYKSRVLELNASDDRGINV 89
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG-EDWRENFLELNASDERGIDV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 90 VRTKIKDFA-AVAVGSArkggypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKF 168
Cdd:PRK00440 85 IRNKIKEFArTAPVGGA--------PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 169 RFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLfGSSISSTDLISVSG-AIPEDvVKSL 247
Cdd:PRK00440 157 RFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAAT-GKEVTEEAVYKITGtARPEE-IREM 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 248 LASCKSGEFDVANKEVNNIIADgYPVS--QLISQFLDVIVNAdDIPDEQKARICKKLGEADKCLVDGADEYLQL 319
Cdd:PRK00440 235 IELALNGDFTEAREKLRDLMID-YGLSgeDIIKQIHREVWSL-DIPEELKVELIDAIGEADFRITEGANERIQL 306
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
10-320 |
1.67e-85 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 260.82 E-value: 1.67e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 10 PWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLYGPeLYKSRVLELNASDDRGINV 89
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGP-NYKEAVLELNASDDRGIDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 90 VRTKIKDFAAvavgsaRKGGYPCPPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFR 169
Cdd:PLN03025 81 VRNKIKMFAQ------KKVTLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 170 FKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGsSISSTDLISVSGAIPEDVVKSLLA 249
Cdd:PLN03025 155 FSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFG-FVNQENVFKVCDQPHPLHVKNIVR 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 250 SCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIVNAdDIPDEQKARICKKLGEADKCLVDGADEYLQLL 320
Cdd:PLN03025 234 NCLKGKFDDACDGLKQLYDLGYSPTDIITTLFRVVKNY-DMPEFLKLEYLREIGFAHMRICDGVGSLLQLS 303
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
1-319 |
3.37e-71 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 224.48 E-value: 3.37e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 1 MAPLvpssqpWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLYGpELYKSRVLELN 80
Cdd:PRK12402 1 DAPL------WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYG-DPWENNFTEFN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 81 ASD--DRG------------------------INVVRTKIKDFAAVAVGSArkggypcpPYKIIILDEADSMTEDAQNAL 134
Cdd:PRK12402 74 VADffDQGkkylvedprfahflgtdkrirsskIDNFKHVLKEYASYRPLSA--------DYKTILLDNAEALREDAQQAL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 135 RRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK12402 146 RRIMEQYSRTCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAIL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 215 YLQSAArLFGSSISSTDLISVSGAIP-EDVVKSLLASCKSGEFDVANKEVNN-IIADGYPVSQLISQFLDVIVNADDipD 292
Cdd:PRK12402 226 TLQTAA-LAAGEITMEAAYEALGDVGtDEVIESLLDAAEAGDFTDARKTLDDlLIDEGLSGGEVLEELLRVARSRYR--G 302
|
330 340
....*....|....*....|....*..
gi 2547841212 293 EQKARICKKLGEADKCLVDGADEYLQL 319
Cdd:PRK12402 303 DNLARLHRLAADADARLTDGANDRIQL 329
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
56-319 |
3.91e-62 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 212.01 E-value: 3.91e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 56 TTTALAIAYQLYGpELYKSRVLELNASDDRGINVVRTKIKDFAAVA-VGSArkggypcpPYKIIILDEADSMTEDAQNAL 134
Cdd:PRK04132 580 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFARTKpIGGA--------SFKIIFLDEADALTQDAQQAL 650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 135 RRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK04132 651 RRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAIN 730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 215 YLQSAARLfGSSISSTDLISV-SGAIPEDVVKSLLASCKsGEFDVANKEVNNIIAD-GYPVSQLISQFLDVIVNAdDIPD 292
Cdd:PRK04132 731 ILQAAAAL-DDKITDENVFLVaSRARPEDIREMMLLALK-GNFLKAREKLREILLKqGLSGEDVLVQMHREVFNL-PIDE 807
|
250 260
....*....|....*....|....*..
gi 2547841212 293 EQKARICKKLGEADKCLVDGADEYLQL 319
Cdd:PRK04132 808 PKKVELADKIGEYNFRLVEGANEMIQL 834
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
26-325 |
1.58e-55 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 182.87 E-value: 1.58e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 26 QEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYG-------------PELYKSR----VLELNA---SDD 84
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCenpeggkacgqchSRLMAAGnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 85 RGINVVRtKIKDFAAVavgSARKGGYpcppyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASR 164
Cdd:COG0470 81 IGIDQIR-ELGEFLSL---TPLEGGR-----KVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 165 CAKFRFKPLSEEVMSNRIlhicNEEGlsLDAQALATLSTISNGDLRRAITYLQSAarlfgssisstdlisvsgAIPEDVV 244
Cdd:COG0470 152 CQVIRFRPPSEEEALAWL----REEG--VDEDALEAILRLAGGDPRAAINLLQAL------------------AGRKELL 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 245 KSLLASCKSGEFDVANKEVNNIIADGYpVSQLISQFLDVIvnADDIPDEQKARICKKLGEADKCLVDGADEYLQLLDVAS 324
Cdd:COG0470 208 EDLAALLSRDRALELLDALLKAEALEL-LDWLLKWLLDNL--PLEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLA 284
|
.
gi 2547841212 325 E 325
Cdd:COG0470 285 K 285
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
1-292 |
8.64e-45 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 155.53 E-value: 8.64e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 1 MAPLVPSSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGP-PGTGKTTTALAIAYQLygpelyKSRVLEL 79
Cdd:PHA02544 1 MITVNPNEFMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEV------GAEVLFV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 80 NASDDRgINVVRTKIKDFAAvavGSARKGGYpcppyKIIILDEAD-SMTEDAQNALRRTMETYSKVTRFFFICNYISRII 158
Cdd:PHA02544 75 NGSDCR-IDFVRNRLTRFAS---TVSLTGGG-----KVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGII 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 159 EPLASRCAKFRF-KPLSEEV------MSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARlfGSSISSTD 231
Cdd:PHA02544 146 EPLRSRCRVIDFgVPTKEEQiemmkqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYAS--TGKIDAGI 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 232 LISVSGAIPEDVVKSLlascKSGEFDVANKEVNNIIADGypvSQLISQFLDV---IVNADDIPD 292
Cdd:PHA02544 224 LSEVTNSDIDDVVEAL----KAKDFKAVRALAPNYANDY---ASFVGKLYDElypQVTPPSIIR 280
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
10-287 |
1.23e-37 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 140.34 E-value: 1.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 10 PWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTA--LAIAYQLYGPELYKS------------ 74
Cdd:PRK14953 5 PFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAyIFAGPRGTGKTTIAriLAKVLNCLNPQEGEPcgkcencveidk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 ----RVLELNASDDRGINVVRTkIKDfaavAVGSARKGGypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFI 150
Cdd:PRK14953 85 gsfpDLIEIDAASNRGIDDIRA-LRD----AVSYTPIKG----KYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILC 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 151 CNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISST 230
Cdd:PRK14953 156 TTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIK 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2547841212 231 DLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIVNA 287
Cdd:PRK14953 236 VVEEFLGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNI 292
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
17-330 |
2.00e-33 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 126.07 E-value: 2.00e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 17 PRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAyqlygpelyKS-------------------RV 76
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILA---------KAlncengptgepcgecescrAI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 77 LELNASD----D-----RGINVVRTkIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTME---TYSKv 144
Cdd:COG2812 77 AAGSHPDvieiDaeasnIGVDDIRE-LIEKVSYAPVEGR--------YKVYIIDEAHMLTTEAFNALLKTLEeppPHVV- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 145 trFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAArLFG 224
Cdd:COG2812 147 --FILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAI-AFG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 225 SSISSTDLISVSGAIPEDVVKSLLASCKsgEFDVANKEVNNIIADgypvsqLISQFLDVIV------NADDIPDEQKARI 298
Cdd:COG2812 224 LLDRRELLLDLLEALLAGDVAALLALAE--ELAKRGRDLKRFLDD------LLSLLRDLLLlklgpdAELLVNEDERERL 295
|
330 340 350
....*....|....*....|....*....|..
gi 2547841212 299 CKklgEADKClvdGADEYLQLLDVASETIRAL 330
Cdd:COG2812 296 QE---LARRL---SPERLLRAIQILLEARREL 321
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
10-220 |
2.47e-33 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 128.50 E-value: 2.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 10 PWVEKYRPRQVKDVAHQEEVVRVLTTTLQT--ADLPH--MLFYGPPGTGKTTTALAIAYQlYGPElyksrVLELNASDDR 85
Cdd:PRK04195 3 PWVEKYRPKTLSDVVGNEKAKEQLREWIESwlKGKPKkaLLLYGPPGVGKTSLAHALAND-YGWE-----VIELNASDQR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 86 GinvvRTKIKDFAAVAVGSARKGGYpcpPYKIIILDEADSM--TEDA--QNALRRTMetysKVTRFFFIC---NYISRII 158
Cdd:PRK04195 77 T----ADVIERVAGEAATSGSLFGA---RRKLILLDEVDGIhgNEDRggARAILELI----KKAKQPIILtanDPYDPSL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 159 EPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAA 220
Cdd:PRK04195 146 RELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIA 207
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
14-285 |
8.14e-32 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 124.11 E-value: 8.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTA--LAIAYQLYGPELYKS---------------- 74
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVAriLAKSLNCENRKGVEPcnecracrsidegtfm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 RVLELNASDDRGINVVRtKIKDfaavAVGSARKGGypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14962 87 DVIELDAASNRGIDEIR-KIRD----AVGYRPMEG----KYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:PRK14962 158 EKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHE 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 235 VSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIV 285
Cdd:PRK14962 238 ALGLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLV 288
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
26-165 |
7.80e-26 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 100.68 E-value: 7.80e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 26 QEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLygpELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSA 105
Cdd:cd00009 3 QEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANEL---FRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFEL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2547841212 106 RKGGYPCppykIIILDEADSMTEDAQNALRRTMETYSKVT------RFFFICNYIS--RIIEPLASRC 165
Cdd:cd00009 80 AEKAKPG----VLFIDEIDSLSRGAQNALLRVLETLNDLRidrenvRVIGATNRPLlgDLDRALYDRL 143
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
13-222 |
8.05e-25 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 103.63 E-value: 8.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 13 EKYRPRQVKDVAHQEEVV---RVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLygpelyKSRVLELNASDDrGINV 89
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT------DAPFEALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 90 VRTKIKDfAAVAVGSARKggypcppyKIIILDEADSMTEDAQNALRRTMETYsKVTrffFIC----N-YISrIIEPLASR 164
Cdd:PRK13342 77 LREVIEE-ARQRRSAGRR--------TILFIDEIHRFNKAQQDALLPHVEDG-TIT---LIGatteNpSFE-VNPALLSR 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 165 CAKFRFKPLSEEVMS---NRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARL 222
Cdd:PRK13342 143 AQVFELKPLSEEDIEqllKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAALG 203
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
14-270 |
9.89e-24 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 101.00 E-value: 9.89e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQLYGPELYKSR----------------- 75
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHAyLFSGIRGTGKTTLARIFAKALNCQNPTEDQepcnqcasckeissgts 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 --VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNY 153
Cdd:PRK06305 90 ldVLEIDGASHRGIEDIR-QINETVLFTPSKSR--------YKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 154 ISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLI 233
Cdd:PRK06305 161 IHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVA 240
|
250 260 270
....*....|....*....|....*....|....*..
gi 2547841212 234 SVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADG 270
Cdd:PRK06305 241 KALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSG 277
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
14-281 |
4.77e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 99.25 E-value: 4.77e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL--YGP-------------ELYK---S 74
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHAyIFFGPRGVGKTTIARILAKRLncENPignepcnectsclEITKgisS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 RVLELNASDDRGINVVRtKIKDfaavAVGSARKGGypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14956 91 DVLEIDAASNRGIENIR-ELRD----NVKFAPMGG----KYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:PRK14956 162 HKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRK 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2547841212 235 VSGAIPEDVVKSLLASCksgeFDVAN-KEVNNIIADGYPVSQLISQFL 281
Cdd:PRK14956 242 MIGYHGIEFLTSFIKSL----IDPDNhSKSLEILESLYQEGQDIYKFL 285
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
14-285 |
1.70e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 98.28 E-value: 1.70e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQL---YGP------------ELYKSR-- 75
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALnceQGLtaepcnvcppcvEITEGRsv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 -VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14965 89 dVFEIDGASNTGVDDIR-ELRENVKYLPSRSR--------YKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:PRK14965 160 HKVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAE 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 235 VSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQ----LISQFLDVIV 285
Cdd:PRK14965 240 LLGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQfcqeLIDHLRNLVV 294
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
11-286 |
3.25e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 97.58 E-value: 3.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 11 WVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQL---YGPELYKS------------ 74
Cdd:PRK07133 8 LYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVAKIFANALncsHKTDLLEPcqecienvnnsl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 RVLELNASDDRGINVVRTKIKDFAAVAVGSarkggypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK07133 88 DIIEMDAASNNGVDEIRELIENVKNLPTQS---------KYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:PRK07133 159 HKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEE 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 235 VSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIVN 286
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKE 290
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
13-283 |
2.23e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 94.52 E-value: 2.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 13 EKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTA--LAIAYQLYGP---------------ELYKS 74
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHAyLFSGPRGVGKTTTArlIAMAVNCSGEdpkpcgecesclavrRGAHP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 RVLELNASDDRGINVVRtkikDFAAVAVGSARKGGYpcppyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14963 86 DVLEIDAASNNSVEDVR----DLREKVLLAPLRGGR-----KVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQsaaRLFGSSISSTdLIS 234
Cdd:PRK14963 157 EKMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLE---RLLALGTPVT-RKQ 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 235 VSGAI---PEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDV 283
Cdd:PRK14963 233 VEEALglpPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGLLEA 284
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
239-324 |
3.73e-21 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 85.99 E-value: 3.73e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 239 IPEDVVKSLLASCKSGEFDVANKEVNN-IIADGYPVSQLISQFLDVIVNaDDIPDEQKARICKKLGEADKCLVDGADEYL 317
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVRElLVEKGYSLQDIITQLHRVVKS-LDLPEEVKLELLEKLGEIEYRLSEGASEKL 79
|
....*..
gi 2547841212 318 QLLDVAS 324
Cdd:pfam08542 80 QLSALLA 86
|
|
| holB |
TIGR00678 |
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ... |
31-212 |
4.40e-21 |
|
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273213 [Multi-domain] Cd Length: 188 Bit Score: 89.22 E-value: 4.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 31 RVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPELY--------KSRVLELNAS-----------DDRGINVV 90
Cdd:TIGR00678 2 QQLKRALEKGRLAHaYLFTGPEGVGKELLALALAKALLCEQRGggepcgecHSCRLIEAGNhpdlhrlepegQSIKVDQV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 91 RTKIKDFAAVAVGSarkggypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRF 170
Cdd:TIGR00678 82 RELVEFLSRTPQES---------GRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPF 152
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2547841212 171 KPLSEEVMSNRIlhicNEEGLS-LDAQALATLstiSNGDLRRA 212
Cdd:TIGR00678 153 PPLSEEALLQWL----IRQGISeEAAELLLAL---AGGSPGRA 188
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
7-295 |
1.89e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 92.12 E-value: 1.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL-------YGP--------E 70
Cdd:PRK14969 2 SYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAyLFTGTRGVGKTTLARILAKSLncetgvtATPcgvcsaclE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 71 LYKSR---VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRF 147
Cdd:PRK14969 82 IDSGRfvdLIEVDAASNTQVDAMR-ELLDNAQYAPTRGR--------FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 148 FFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSI 227
Cdd:PRK14969 153 ILATTDPQKIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTV 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 228 SSTDLISVSGAIPEDVV------------KSLLASCKSGE-----FDVANKEVNNIIADgYPVSQLISQFLDvivnaDDI 290
Cdd:PRK14969 233 NESEVRAMLGAIDQDYLfalleallaqdgAALLAIADAMEerslsFDAALQDLAALLHR-LAIAQTVPDSIA-----DDL 306
|
....*
gi 2547841212 291 PDEQK 295
Cdd:PRK14969 307 PERDR 311
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
7-278 |
3.61e-20 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 91.37 E-value: 3.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL---YGP------ELYKSR- 75
Cdd:PRK06647 2 SYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAyIFSGPRGVGKTSSARAFARCLncvNGPtpmpcgECSSCKs 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 --------VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRF 147
Cdd:PRK06647 82 idndnsldVIEIDGASNTSVQDVR-QIKEEIMFPPASSR--------YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 148 FFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSI 227
Cdd:PRK06647 153 IFATTEVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDI 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 228 SSTDLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLIS 278
Cdd:PRK06647 233 TLEQIRSKMGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLL 283
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
7-284 |
4.47e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 91.02 E-value: 4.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTA--LAIAYQLYGPE------------- 70
Cdd:PRK14950 2 TVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAyLFTGPRGVGKTSTAriLAKAVNCTTNDpkgrpcgtcemcr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 71 -LYKSR---VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTR 146
Cdd:PRK14950 82 aIAEGSavdVIEMDAASHTSVDDAR-EIIERVQFRPALAR--------YKVYIIDEVHMLSTAAFNALLKTLEEPPPHAI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 147 FFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSS 226
Cdd:PRK14950 153 FILATTEVHKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGE 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2547841212 227 ISSTDLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVI 284
Cdd:PRK14950 233 ISLSQVQSLLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYL 290
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
7-248 |
5.20e-20 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 90.92 E-value: 5.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL------YGP---------E 70
Cdd:PRK08691 2 AYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAyLLTGTRGVGKTTIARILAKSLncenaqHGEpcgvcqsctQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 71 LYKSR---VLELNASDDRGINVVRTKIKDfAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRF 147
Cdd:PRK08691 82 IDAGRyvdLLEIDAASNTGIDNIREVLEN-AQYAPTAGK--------YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 148 FFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSI 227
Cdd:PRK08691 153 ILATTDPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKV 232
|
250 260
....*....|....*....|.
gi 2547841212 228 SSTDLISVSGAIPEDVVKSLL 248
Cdd:PRK08691 233 AENDVRQMIGAVDKQYLYELL 253
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
13-286 |
2.97e-19 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 88.75 E-value: 2.97e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 13 EKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTA--LAIAYQLYGP------------ELYKSR-- 75
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAkiFAKAINCLNPkdgdccnscsvcESINTNqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 --VLELNASDDRGINVVRtKIKD--FAAVAVGSarkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFIC 151
Cdd:PRK05896 88 vdIVELDAASNNGVDEIR-NIIDniNYLPTTFK----------YKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 152 NYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTD 231
Cdd:PRK05896 157 TEFQKIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIED 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 232 LISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLDVIVN 286
Cdd:PRK05896 237 INKTFGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLID 291
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
45-173 |
3.41e-19 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 82.26 E-value: 3.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQLYGPelyksrVLELNASD--DRGINVVRTKIKDFAAVAVGSArkggyPCppykIIILDE 122
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAP------FIEISGSElvSKYVGESEKRLRELFEAAKKLA-----PC----VIFIDE 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 123 ADSM-----------TEDAQNALRRTMETYSKVT-RFFFIC--NYISRIIEPLASRCAKFRFKPL 173
Cdd:pfam00004 66 IDALagsrgsggdseSRRVVNQLLTELDGFTSSNsKVIVIAatNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
14-282 |
1.93e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 86.08 E-value: 1.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVvrvlTTTLQTADLPH-----MLFYGPPGTGKTTTA--LAIAYQ-LYGP--------ELYKS--- 74
Cdd:PRK05563 9 KWRPQTFEDVVGQEHI----TKTLKNAIKQGkishaYLFSGPRGTGKTSAAkiFAKAVNcLNPPdgepcnecEICKAitn 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 ----RVLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMEtyskvtrfffi 150
Cdd:PRK05563 85 gslmDVIEIDAASNNGVDEIR-DIRDKVKYAPSEAK--------YKVYIIDEVHMLSTGAFNALLKTLE----------- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 151 cnyisriiEP-------LA------------SRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRR 211
Cdd:PRK05563 145 --------EPpahvifiLAttephkipatilSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRD 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 212 AITYLQSAARLFGSSISSTDLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGYPVSQLISQFLD 282
Cdd:PRK05563 217 ALSILDQAISFGDGKVTYEDALEVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIY 287
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
14-270 |
4.82e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 84.84 E-value: 4.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQL---YGP---------------ELYKS 74
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCARIISLCLncsNGPtsdpcgtchncisikNSNHP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 RVLELNASDDRGINVVRTKIKDFAAVAVGSArkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14964 86 DVIEIDAASNTSVDDIKVILENSCYLPISSK---------FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTD--- 231
Cdd:PRK14964 157 KKIPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSvrd 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2547841212 232 -LISVSGAIPEDVVKSLLASCKSGEFDVANKEVNN----IIADG 270
Cdd:PRK14964 237 lLGCVDKHILEDLVEAILLGDAQSALNVFRELCNTsnpvIILEG 280
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
14-242 |
1.09e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 82.94 E-value: 1.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL-------YGP--------ELYKSRVL 77
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLncqngitSNPcrkciickEIEKGLCL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 78 ELNASDdrgiNVVRTKIKDFAAVAvgsarKGGYPCPPY---KIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK14961 89 DLIEID----AASRTKVEEMREIL-----DNIYYSPSKsrfKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:PRK14961 160 EKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTD 239
|
....*...
gi 2547841212 235 VSGAIPED 242
Cdd:PRK14961 240 MLGLLNEK 247
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
7-228 |
2.86e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 82.81 E-value: 2.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADL-PHMLFYGPPGTGKTTTALAIAYQLYGPELYKSR---------- 75
Cdd:PRK14959 2 SHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEpcntceqcrk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 --------VLELNASDDRGINVVRtKIKDfaavAVGSARKGGYpcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRF 147
Cdd:PRK14959 82 vtqgmhvdVVEIDGASNRGIDDAK-RLKE----AIGYAPMEGR----YKVFIIDEAHMLTREAFNALLKTLEEPPARVTF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 148 FFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSI 227
Cdd:PRK14959 153 VLATTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRL 232
|
.
gi 2547841212 228 S 228
Cdd:PRK14959 233 T 233
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
10-234 |
5.86e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 81.44 E-value: 5.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 10 PWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPELY---------------- 72
Cdd:PRK06645 10 PFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVNCSALItenttiktceqctnci 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 73 ------KSRVLELNASDDRGINVVRTKIKDFAAVAVGSArkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTR 146
Cdd:PRK06645 90 sfnnhnHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGK---------HKIFIIDEVHMLSKGAFNALLKTLEEPPPHII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 147 FFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLfgsS 226
Cdd:PRK06645 161 FIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASM---S 237
|
....*...
gi 2547841212 227 ISSTDLIS 234
Cdd:PRK06645 238 AKSDNIIS 245
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
9-283 |
1.69e-16 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 80.48 E-value: 1.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 9 QPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQLYGPELYKSRVLELNAS----- 82
Cdd:PRK14960 3 QVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAyLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATckavn 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 83 DDRGINVV------RTKIKDFAAVAvgsarkGGYPCPP----YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICN 152
Cdd:PRK14960 83 EGRFIDLIeidaasRTKVEDTRELL------DNVPYAPtqgrFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 153 YISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDL 232
Cdd:PRK14960 157 DPQKLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDV 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 233 ISVSGAIPEDVVKSLLASCKSGEFDvankevnniiadgyPVSQLISQF----LDV 283
Cdd:PRK14960 237 KEMLGLIDRTIIYDLILAVHQNQRE--------------KVSQLLLQFryqaLDV 277
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
14-219 |
2.38e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 79.69 E-value: 2.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQLY---GPelyKSR-------------- 75
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHAyLFSGLRGSGKTSSARIFARALVceqGP---SSTpcdtciqcqsalen 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 ----VLELNASDDRGINVVR-----TKIKDfaavavGSARkggypcppYKIIILDEADSMTEDAQNALRRTME---TYSK 143
Cdd:PRK08451 84 rhidIIEMDAASNRGIDDIRelieqTKYKP------SMAR--------FKIFIIDEVHMLTKEAFNALLKTLEeppSYVK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 144 vtrffficnYISRIIEPLA------SRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQ 217
Cdd:PRK08451 150 ---------FILATTDPLKlpatilSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLD 220
|
..
gi 2547841212 218 SA 219
Cdd:PRK08451 221 QA 222
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
6-222 |
3.10e-16 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 78.94 E-value: 3.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 6 PSSQPWVEKYRPRQVKDVAHQEEVV---RVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQLygpelyKSRVLELNAs 82
Cdd:COG2256 10 AANAPLAERMRPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANAT------DAEFVALSA- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 83 ddrginvVRTKIKDFAAVaVGSARK---GGYPCppykIIILDEADSMTEDAQNAL-----RRTmetyskVTrffFIC--- 151
Cdd:COG2256 83 -------VTSGVKDIREV-IEEARErraYGRRT----ILFVDEIHRFNKAQQDALlphveDGT------IT---LIGatt 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 152 -N-YISrIIEPLASRCAKFRFKPLSEEVMS---NRILH----ICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARL 222
Cdd:COG2256 142 eNpSFE-VNSALLSRCRVFVLKPLSEEDLEqllERALAdderGLGGYKLELDDEALEALARLADGDARRALNALELAVLS 220
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
7-292 |
6.77e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 78.01 E-value: 6.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPELYKS----------- 74
Cdd:PRK14955 2 SYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqevtepc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 ---------------RVLELNASDDRGINVVRTKIKDfaaVAVGSaRKGgypcpPYKIIILDEADSMTEDAQNALRRTME 139
Cdd:PRK14955 82 gecescrdfdagtslNISEFDAASNNSVDDIRLLREN---VRYGP-QKG-----RYRVYIIDEVHMLSIAAFNAFLKTLE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 140 TYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQsa 219
Cdd:PRK14955 153 EPPPHAIFIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILD-- 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 220 aRLFGSSISSTDlisvSGAIPEDVVKSLLASCKSGEFdvanKEVNNIIADGYPVSQL-ISQFldVIVNADDIPD 292
Cdd:PRK14955 231 -QVIAFSVESEG----EGSIRYDKVAELLNYIDDEHF----FAVTDAVADGDAVAMLdVAQF--VIRNGYDEQD 293
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
14-214 |
1.02e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 77.22 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGP------ELYKSRVLELNASDDRG 86
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPgyddpnEDFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 87 INVVRTKIKDFAAvavgsarkggypcPP----YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLA 162
Cdd:PRK14970 90 VDDIRNLIDQVRI-------------PPqtgkYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 163 SRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK14970 157 SRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALS 208
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
7-214 |
8.25e-15 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 75.30 E-value: 8.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTA--LAIAYQLYGP-------------- 69
Cdd:PRK12323 2 SYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAyLFTGTRGVGKTTLSriLAKSLNCTGAdgeggitaqpcgqc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 70 ----ELYKSRV---LELNASDDRGINVVrTKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYS 142
Cdd:PRK12323 82 ractEIDAGRFvdyIEMDAASNRGVDEM-AQLLDKAVYAPTAGR--------FKVYMIDEVHMLTNHAFNAMLKTLEEPP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 143 KVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK12323 153 EHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALS 224
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
14-285 |
8.95e-15 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 74.92 E-value: 8.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL---YGP------------ELYKS--- 74
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHAyLFSGPRGCGKTSSARILARSLncaQGPtatpcgvcescvALAPNgpg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 --RVLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICN 152
Cdd:PRK14952 86 siDVVELDAASHGGVDDTR-ELRDRAFYAPAQSR--------YRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 153 YISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYL-QSAARLFGSSISSTD 231
Cdd:PRK14952 157 EPEKVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLdQLLAGAADTHVTYQR 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2547841212 232 LISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADGY-PV---SQLISQFLDVIV 285
Cdd:PRK14952 237 ALGLLGATDVALIDDAVDALAADDAAALFGAIESVIDAGHdPRrfaTDLLERFRDLIV 294
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
7-248 |
1.75e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 74.35 E-value: 1.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQLYGPELYKSR---------- 75
Cdd:PRK14957 2 SYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAyLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEpcnkcencva 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 76 --------VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRF 147
Cdd:PRK14957 82 innnsfidLIEIDAASRTGVEETK-EILDNIQYMPSQGR--------YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 148 FFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSI 227
Cdd:PRK14957 153 ILATTDYHKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGEL 232
|
250 260
....*....|....*....|.
gi 2547841212 228 SSTDLISVSGAIPEDVVKSLL 248
Cdd:PRK14957 233 KQAQIKQMLGIIDSEEVYSII 253
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
26-174 |
3.52e-14 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 69.16 E-value: 3.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 26 QEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLY----GPELYKS------RVLELN-------ASDDRGI 87
Cdd:pfam13177 2 QPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFceepGDDLPCGqcrscrRIESGNhpdlviiEPEGQSI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 88 NV--VRTKIKDFAAVAVGSarkggypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRC 165
Cdd:pfam13177 82 KIdqIRELQKEFSKSPYEG---------KKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRC 152
|
....*....
gi 2547841212 166 AKFRFKPLS 174
Cdd:pfam13177 153 QIIRFKPLS 161
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
173-232 |
4.28e-14 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 66.01 E-value: 4.28e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 173 LSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGsSISSTDL 232
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGG-VITEEDV 59
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
7-216 |
8.51e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 72.28 E-value: 8.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPEL-----YKSRVLE-- 78
Cdd:PRK14954 2 SYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKAVNCQRMiddpvYLQEVTEpc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 79 --------------LNASD-DRGINVVRTKIKDFAAVAVGSARKGgypcpPYKIIILDEADSMTEDAQNALRRTMETYSK 143
Cdd:PRK14954 82 gecescrdfdagtsLNISEfDAASNNSVDDIRQLRENVRYGPQKG-----RYRVYIIDEVHMLSTAAFNAFLKTLEEPPP 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2547841212 144 VTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYL 216
Cdd:PRK14954 157 HAIFIFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSIL 229
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
27-213 |
4.37e-13 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 69.30 E-value: 4.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 27 EEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLY---GPELYKSRVL--ELNASDDRGI------NV----- 89
Cdd:PRK09112 29 EEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILshpDPAEAPETLAdpDPASPVWRQIaqgahpNLlhitr 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 90 -VRTKIKDF-AAVAVGSARKGGY------PCPPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPL 161
Cdd:PRK09112 109 pFDEKTGKFkTAITVDEIRRVGHflsqtsGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTI 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 162 ASRCAKFRFKPLSEEVMSNRILHIcnEEGLSLDAQALATLSTISNGDLRRAI 213
Cdd:PRK09112 189 RSRCQPISLKPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKAL 238
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
14-250 |
1.36e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 68.59 E-value: 1.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTA--LAIAYQLYGP------------------ELY 72
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHAyLFTGTRGVGKTTVSriLAKSLNCQGPdgqggitatpcgvcqacrDID 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 73 KSRVL---ELNASDDRGINVVrTKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFF 149
Cdd:PRK14951 89 SGRFVdytELDAASNRGVDEV-QQLLEQAVYKPVQGR--------FKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 150 ICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITyLQSAARLFGssiss 229
Cdd:PRK14951 160 ATTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALS-LTDQAIAFG----- 233
|
250 260
....*....|....*....|.
gi 2547841212 230 tdlisvSGAIPEDVVKSLLAS 250
Cdd:PRK14951 234 ------SGQLQEAAVRQMLGS 248
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
27-207 |
1.46e-12 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 67.36 E-value: 1.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 27 EEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQLYGPELYKSRVlelnasddrgiNVVRTKIKDFAAVAVGSA 105
Cdd:PRK05564 10 ENIKNRIKNSIIKNRFSHAhIIVGEDGIGKSLLAKEIALKILGKSQQREYV-----------DIIEFKPINKKSIGVDDI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 106 R-------KGGYPCPPyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVM 178
Cdd:PRK05564 79 RniieevnKKPYEGDK-KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEI 157
|
170 180
....*....|....*....|....*....
gi 2547841212 179 SNRIlhicNEEGLSLDAQALATLSTISNG 207
Cdd:PRK05564 158 EKFI----SYKYNDIKEEEKKSAIAFSDG 182
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
44-170 |
1.49e-12 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 64.32 E-value: 1.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALAIAYQLYGPElykSRVLELNASDDRGINVVRTKIKDFAAVAVGS------------ARKggyp 111
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPG---GGVIYIDGEDILEEVLDQLLLIIVGGKKASGsgelrlrlalalARK---- 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2547841212 112 cPPYKIIILDEADSMTEDAQNALRRTMETYSKV--------TRFFFICNYISRIIEPLASRCAKFRF 170
Cdd:smart00382 77 -LKPDVLILDEITSLLDAEQEALLLLLEELRLLlllkseknLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
14-199 |
2.69e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 67.62 E-value: 2.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPH--MLfYGPPGTGKTTTALAIAYQL--------YGPEL------------ 71
Cdd:PRK09111 17 KYRPQTFDDLIGQEAMVRTLTNAFETGRIAQafML-TGVRGVGKTTTARILARALnyegpdgdGGPTIdlcgvgehcqai 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 72 YKSR---VLELNASDDRGINVVRtKIKD---FAAVavgSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVT 145
Cdd:PRK09111 96 MEGRhvdVLEMDAASHTGVDDIR-EIIEsvrYRPV---SAR--------YKVYIIDEVHMLSTAAFNALLKTLEEPPPHV 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 146 RFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALA 199
Cdd:PRK09111 164 KFIFATTEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALA 217
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
9-58 |
4.18e-12 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 67.17 E-value: 4.18e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2547841212 9 QPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHMLFYGPPGTGKTTT 58
Cdd:PRK04132 7 KPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT 56
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
14-214 |
6.11e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 66.34 E-value: 6.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEvvrvLTTTL----QTADLPH-MLFYGPPGTGKTTTA--LA---------------------IAYQ 65
Cdd:PRK14971 10 KYRPSTFESVVGQEA----LTTTLknaiATNKLAHaYLFCGPRGVGKTTCAriFAktincqnltadgeacnecescVAFN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 66 lygpELYKSRVLELNASDDRGINVVRTKIKdfaavavgSARkggYPcPP---YKIIILDEADSMTEDAQNALRRTMETYS 142
Cdd:PRK14971 86 ----EQRSYNIHELDAASNNSVDDIRNLIE--------QVR---IP-PQigkYKIYIIDEVHMLSQAAFNAFLKTLEEPP 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 143 KVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK14971 150 SYAIFILATTEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALS 221
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
26-218 |
3.17e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 63.38 E-value: 3.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 26 QEEVVRVLTTTLQTADL-PHMLFYGPPGTGKTTTAL----AIAYQLYGPELYKSRVLELNASDDRGIN---VVRTK-IKD 96
Cdd:PRK07399 9 QPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALcfieGLLSQGSPSKNIRRRLEEGNHPDLLWVEptyQHQGKlITA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 97 FAAVAVGSARKGgypcPPY----------------------KIIILDEADSMTEDAQNALRRTMETYSKVTrFFFICNYI 154
Cdd:PRK07399 89 SEAEEAGLKRKA----PPQirleqireikrflsrppleaprKVVVIEDAETMNEAAANALLKTLEEPGNGT-LILIAPSP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMsNRILHIC-NEEGLSLDAQALATLSTISNGDLRRAITYLQS 218
Cdd:PRK07399 164 ESLLPTIVSRCQIIPFYRLSDEQL-EQVLKRLgDEEILNINFPELLALAQGSPGAAIANIEQLQS 227
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
44-233 |
3.71e-11 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 63.78 E-value: 3.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALAIAYQLygpelyksrvlelnasddrGINVVRTKIKDFAAVAVG-SARK---------GGYPCp 113
Cdd:COG0464 193 GLLLYGPPGTGKTLLARALAGEL-------------------GLPLIEVDLSDLVSKYVGeTEKNlrevfdkarGLAPC- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 114 pykIIILDEADSM----TEDAQNALRRT-------METYSKvtRFFFIC--NYISRIIEPLASRCA-KFRFKPLSEEVMS 179
Cdd:COG0464 253 ---VLFIDEADALagkrGEVGDGVGRRVvntllteMEELRS--DVVVIAatNRPDLLDPALLRRFDeIIFFPLPDAEERL 327
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2547841212 180 nRIL-HICNEEGLS--LDAQALATLST-ISNGDLRRAITY-LQSAARLFGSSISSTDLI 233
Cdd:COG0464 328 -EIFrIHLRKRPLDedVDLEELAEATEgLSGADIRNVVRRaALQALRLGREPVTTEDLL 385
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
16-214 |
4.64e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 63.12 E-value: 4.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 16 RPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL--YGPELYKSRV-----LELNASD---- 83
Cdd:PRK07471 14 HPRETTALFGHAAAEAALLDAYRSGRLHHAwLIGGPQGIGKATLAYRMARFLlaTPPPGGDGAVppptsLAIDPDHpvar 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 84 -------------DRGINVVRTKIKDfaAVAVGSARK-----------GGYpcppyKIIILDEADSMTEDAQNALRRTME 139
Cdd:PRK07471 94 riaagahgglltlERSWNEKGKRLRT--VITVDEVRElisffgltaaeGGW-----RVVIVDTADEMNANAANALLKVLE 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 140 TYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSnRILHicnEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK07471 167 EPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVI-DALA---AAGPDLPDDPRAALAALAEGSVGRALR 237
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
7-219 |
1.00e-10 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 62.76 E-value: 1.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVV---RVLTTTLQTADLPHMLFYGPPGTGKTTTALAIAYQlygpelYKSRVLELNAsd 83
Cdd:PRK13341 14 SEAPLADRLRPRTLEEFVGQDHILgegRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANH------TRAHFSSLNA-- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 84 drginvVRTKIKDF-AAVAVGSARKGGYpcPPYKIIILDEADSMTEDAQNAL-----RRTMETYSKVTR--FFficnyis 155
Cdd:PRK13341 86 ------VLAGVKDLrAEVDRAKERLERH--GKRTILFIDEVHRFNKAQQDALlpwveNGTITLIGATTEnpYF------- 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 156 RIIEPLASRCAKFRFKPLSEEVMS---NRILHICnEEG-----LSLDAQALATLSTISNGDLRRAITYLQSA 219
Cdd:PRK13341 151 EVNKALVSRSRLFRLKSLSDEDLHqllKRALQDK-ERGygdrkVDLEPEAEKHLVDVANGDARSLLNALELA 221
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
9-253 |
1.64e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 61.90 E-value: 1.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 9 QPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADL-PHMLFYGPPGTGKTTTALAIAYQLY-----GP--------ELYKS 74
Cdd:PRK14948 4 EPLHHKYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSARILAKSLNclnsdKPtpepcgkcELCRA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 75 -------RVLELNASDDRGINVVRTKIK--DFAAVavgSARkggypcppYKIIILDEADSMTEDAQNALRRTMEtyskvt 145
Cdd:PRK14948 84 iaagnalDVIEIDAASNTGVDNIRELIEraQFAPV---QAR--------WKVYVIDECHMLSTAAFNALLKTLE------ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 146 rffficnyisriiEP-------LA------------SRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISN 206
Cdd:PRK14948 147 -------------EPpprvvfvLAttdpqrvlptiiSRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQ 213
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2547841212 207 GDLRRAITYLQSAARLFGS-----------SISSTDLISVSGAIPEDVVKSLLASCKS 253
Cdd:PRK14948 214 GGLRDAESLLDQLSLLPGPitpeavwdllgAVPEQDLLNLLKALASNDPESLLDSCRQ 271
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
14-214 |
1.92e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 62.17 E-value: 1.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL-------YGP--------ELYKSRVL 77
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHAyLFTGTRGVGKTTLSRIFAKALncetgvtSQPcgvcracrEIDEGRFV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 78 ---ELNASDDRGINVVrTKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYI 154
Cdd:PRK07003 89 dyvEMDAASNRGVDEM-AALLERAVYAPVDAR--------FKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 155 SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAIT 214
Cdd:PRK07003 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALS 219
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
7-219 |
2.05e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 61.67 E-value: 2.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 7 SSQPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL-------YGP--------E 70
Cdd:PRK14958 2 AHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAyLFTGTRGVGKTTISRILAKCLncekgvsANPcndcencrE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 71 LYKSRVLELNASDdrgiNVVRTKIKDFAAVAvgsarkGGYPCPP----YKIIILDEADSMTEDAQNALRRTMETYSKVTR 146
Cdd:PRK14958 82 IDEGRFPDLFEVD----AASRTKVEDTRELL------DNIPYAPtkgrFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVK 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2547841212 147 FFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSA 219
Cdd:PRK14958 152 FILATTDHHKLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQS 224
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
9-266 |
6.12e-10 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 60.36 E-value: 6.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 9 QPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-----MLFYGPPGTGKTTTA------LAIAYQLY-GPELYKSRV 76
Cdd:TIGR00602 72 EPWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIkilskeLGIQVQEWsNPTLPDFQK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 77 LELNASDDRGINVVR--TKIKDFAAVAVGSARKGGYPCPPY----KIIILDEADSMTEDAQNALRRTMET-YSKVTRF-F 148
Cdd:TIGR00602 152 NDHKVTLSLESCFSNfqSQIEVFSEFLLRATNKLQMLGDDLmtdkKIILVEDLPNQFYRDTRALHEILRWkYVSIGRCpL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 149 FICnyISRIIEPLAS--------------------RCAKFRFKPLSEEVMSNRILHICNEEG-------LSLDAQALATL 201
Cdd:TIGR00602 232 VFI--ITESLEGDNNqrrllfpaetimnkeileepRVSNISFNPIAPTIMKKFLNRIVTIEAkkngekiKVPKKTSVELL 309
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 202 STISNGDLRRAITYLQsaarlFGSSISSTDLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNI 266
Cdd:TIGR00602 310 CQGCSGDIRSAINSLQ-----FSSSKSGSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQAL 369
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
28-222 |
4.38e-09 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 56.50 E-value: 4.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 28 EVVRVLTTTLQTA-DLPHM-LFYGPPGTGKTTTALAIAYQLYG------PELYKSRVL--ELnaSDDRGINVVRTKIKDF 97
Cdd:COG2842 34 KNVRRFAEALDEArALPGIgVVYGESGVGKTTAAREYANRNPNviyvtaSPSWTSKELleEL--AEELGIPAPPGTIADL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 98 AAVAVGSARKGGYPcppykiIILDEADSMTEDAQNALRR-------------TMETYSKVTRFfficnyisriiEPLASR 164
Cdd:COG2842 112 RDRILERLAGTGRL------LIIDEADHLKPKALEELRDihdetgvgvvligMERLPAKLKRY-----------EQLYSR 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2547841212 165 CAK-FRFKPLSEEvmsnRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARL 222
Cdd:COG2842 175 IGFwVEFKPLSLE----DVRALAEAWGELTDPDLLELLHRITRGNLRRLDRTLRLAARA 229
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
173-234 |
6.01e-09 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 51.70 E-value: 6.01e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 173 LSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLIS 234
Cdd:cd18133 1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRVY 62
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
44-139 |
6.39e-08 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 52.96 E-value: 6.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALAIAYQLygpelyKSRVLELNASD-------DRGINVVrtKIKDFAAvavgsarkgGYPCppyk 116
Cdd:COG1223 37 KILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLDSligsylgETARNLR--KLFDFAR---------RAPC---- 95
|
90 100
....*....|....*....|...
gi 2547841212 117 IIILDEADSMtedaqnALRRTME 139
Cdd:COG1223 96 VIFFDEFDAI------AKDRGDQ 112
|
|
| PRK08058 |
PRK08058 |
DNA polymerase III subunit delta'; Validated |
26-201 |
7.71e-08 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181214 [Multi-domain] Cd Length: 329 Bit Score: 53.01 E-value: 7.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 26 QEEVVRVLTTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPELYKS----------RVLELN-------ASDDRGI 87
Cdd:PRK08058 11 QPVVVKMLQNSIAKNRLSHaYLFEGAKGTGKKATALWLAKSLFCLERNGVepcgtctnckRIDSGNhpdvhlvAPDGQSI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 88 NV--VRTKIKDFAAVAVGSARKggypcppykIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRC 165
Cdd:PRK08058 91 KKdqIRYLKEEFSKSGVESNKK---------VYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRC 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 2547841212 166 AKFRFKPLSEEVMSNRILhicnEEGLSL-DAQALATL 201
Cdd:PRK08058 162 QVVEFRPLPPESLIQRLQ----EEGISEsLATLLAGL 194
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
45-164 |
8.22e-08 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 51.13 E-value: 8.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQLyGPELYKsrvleLNASD--DRGINVVRTKIKDFAAVAVGSArkggyPCppykIIILDE 122
Cdd:cd19481 29 ILLYGPPGTGKTLLAKALAGEL-GLPLIV-----VKLSSllSKYVGESEKNLRKIFERARRLA-----PC----ILFIDE 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2547841212 123 ADSM------------TEDAQNALRRTMETYSKVTRFFFIC--NYISRIIEPLASR 164
Cdd:cd19481 94 IDAIgrkrdssgesgeLRRVLNQLLTELDGVNSRSKVLVIAatNRPDLLDPALLRP 149
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
16-63 |
9.57e-08 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 50.96 E-value: 9.57e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2547841212 16 RPRQVKDVAHQEEVVRVLTTTLQTAD-----LPHMLFYGPPGTGKTTTALAIA 63
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHVLLYGPPGLGKTTLANIIA 54
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
115-263 |
1.12e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 52.50 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 115 YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRIlhicNEEGLSLD 194
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAMQWL----KGQGITVP 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 195 AQAL--------ATLSTISNGDLRRAitylQSAARLFGSSISST--DLISVSGAIPEDVVKSL------LASCKSGEFDV 258
Cdd:PRK06090 185 AYALklnmgsplKTLAMMKEGGLEKY----HKLERQLVDALSGPvsDQLKCASLIAADPLTHLswlwllLTDAQKVHFGV 260
|
....*
gi 2547841212 259 ANKEV 263
Cdd:PRK06090 261 QNEYY 265
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
25-222 |
1.22e-07 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 52.93 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 25 HQEEVVRVLTTTLQTA---DLPHMLF-YGPPGTGKTTTALAIAyqlygpelyksRVLElNASDDRGINV----VRTKIKD 96
Cdd:COG1474 30 HREEEIEELASALRPAlrgERPSNVLiYGPTGTGKTAVAKYVL-----------EELE-EEAEERGVDVrvvyVNCRQAS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 97 --FAAVA-VGSARKGGYPCPP--------YK-------------IIILDEADSMTEDAQN----ALRRTMETY--SKVTr 146
Cdd:COG1474 98 trYRVLSrILEELGSGEDIPStglstdelFDrlyealderdgvlVVVLDEIDYLVDDEGDdllyQLLRANEELegARVG- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 147 FFFICNYISrIIEPLASR------CAKFRFKPLS----EEVMSNRIlhicnEEGL---SLDAQAL---ATLSTISNGDLR 210
Cdd:COG1474 177 VIGISNDLE-FLENLDPRvksslgEEEIVFPPYDadelRDILEDRA-----ELAFydgVLSDEVIpliAALAAQEHGDAR 250
|
250
....*....|..
gi 2547841212 211 RAITYLQSAARL 222
Cdd:COG1474 251 KAIDLLRVAGEI 262
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
16-66 |
1.59e-07 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 52.39 E-value: 1.59e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2547841212 16 RPRQVKDVAHQEEVVRVLTTTLQTAD-----LPHMLFYGPPGTGKTTTALAIAYQL 66
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTTLAHIIANEM 78
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
16-66 |
1.78e-07 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 52.06 E-value: 1.78e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2547841212 16 RPRQVKDVAHQEEVVRVLTTTLQTAD-----LPHMLFYGPPGTGKTTTALAIAYQL 66
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTTLANIIANEM 75
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
44-150 |
8.78e-07 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 47.34 E-value: 8.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALAIAYQLygpELYKSRVLELNASDDRGINVVRTKIkdfaAVAVGSARKGGYP------------ 111
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQL---PEVRDSVVFVDLPSGTSPKDLLRAL----LRALGLPLSGRLSkeellaalqqll 79
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2547841212 112 --CPPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFI 150
Cdd:pfam13401 80 laLAVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
40-176 |
3.12e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 48.16 E-value: 3.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 40 ADLPH-MLFYGPPGTGKTTTALAIAYQL--------YG---------------PELYksrVLELNASDdRGINVvrTKIK 95
Cdd:PRK05707 19 GRHPHaYLLHGPAGIGKRALAERLAAALlceapqggGAcgsckgcqllragshPDNF---VLEPEEAD-KTIKV--DQVR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 96 DFAAVAVGSARKGGYpcppyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSE 175
Cdd:PRK05707 93 ELVSFVVQTAQLGGR-----KVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSN 167
|
.
gi 2547841212 176 E 176
Cdd:PRK05707 168 E 168
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
46-145 |
1.40e-05 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 44.58 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 46 LFYGPPGTGKTTTALAIA-------YQLYGPELYKSRVLElnasDDRGINVVRTKIKDFAavavgsarkggyPCppykII 118
Cdd:cd19511 31 LLYGPPGCGKTLLAKALAseaglnfISVKGPELFSKYVGE----SERAVREIFQKARQAA------------PC----II 90
|
90 100
....*....|....*....|....*..
gi 2547841212 119 ILDEADSMtedaqnALRRTMETYSKVT 145
Cdd:cd19511 91 FFDEIDSL------APRRGQSDSSGVT 111
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
9-71 |
2.12e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 44.56 E-value: 2.12e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2547841212 9 QPWVEKYRPRQVKDVAHQEEVVRVLTTTLQTADLPH-----MLFYGPPGTGKTTTALAIAYQLyGPEL 71
Cdd:pfam03215 7 EQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL-GPKY 73
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
115-248 |
2.41e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 46.26 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 115 YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLD 194
Cdd:PRK14949 120 FKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFE 199
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 195 AQALATLSTISNGDLRRAITyLQSAARLFGS-SISSTDLISVSGAIPEDVVKSLL 248
Cdd:PRK14949 200 AEALTLLAKAANGSMRDALS-LTDQAIAFGGgQVMLTQVQTMLGSIDEQHVIALL 253
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
26-77 |
3.89e-05 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 44.15 E-value: 3.89e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 2547841212 26 QEEVVRVLTttlQTADLPHMLFYGPPGTGKTTTALAIAYQLYGpELYKSRVL 77
Cdd:cd18038 7 KLAVRNIVT---GTSRPPPYIIFGPPGTGKTVTLVEAILQVLR-QPPEARIL 54
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
26-66 |
4.20e-05 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 44.60 E-value: 4.20e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2547841212 26 QEEVVRVLTTTLQTAD-----LPHMLFYGPPGTGKTTTALAIAYQL 66
Cdd:TIGR00635 9 QEKVKEQLQLFIEAAKmrqeaLDHLLLYGPPGLGKTTLAHIIANEM 54
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
45-126 |
4.24e-05 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 43.27 E-value: 4.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQ-------LYGPELYKSRVLELNASddrginvvrtkIKDFAAVAVGSArkggyPCppykI 117
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANEcqanfisVKGPELLTMWFGESEAN-----------VRDIFDKARAAA-----PC----V 89
|
....*....
gi 2547841212 118 IILDEADSM 126
Cdd:cd19528 90 LFFDELDSI 98
|
|
| PRK06964 |
PRK06964 |
DNA polymerase III subunit delta'; Validated |
40-168 |
5.52e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 235898 [Multi-domain] Cd Length: 342 Bit Score: 44.37 E-value: 5.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 40 ADLPH-MLFYGPPGTGKTTTALAIA-------------------------------YQLYGPElyksrVLELNAS----- 82
Cdd:PRK06964 18 ARLPHaLLLHGQAGIGKLDFAQHLAqgllcetpqpdgepcgtcaacnwfaqgnhpdYRIVRPE-----ALAAEAPgaade 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 83 ------DDRG-----------INVVRTKIkDFaaVAVGSARKGgypcppYKIIILDEADSMTEDAQNALRRTMETYSKVT 145
Cdd:PRK06964 93 akeadaDEGGkktkapskeikIEQVRALL-DF--CGVGTHRGG------ARVVVLYPAEALNVAAANALLKTLEEPPPGT 163
|
170 180
....*....|....*....|...
gi 2547841212 146 RFFFICNYISRIIEPLASRCAKF 168
Cdd:PRK06964 164 VFLLVSARIDRLLPTILSRCRQF 186
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
44-68 |
6.12e-05 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 44.84 E-value: 6.12e-05
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
173-237 |
6.60e-05 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 40.18 E-value: 6.60e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 173 LSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARLFGSSISSTDLISVSG 237
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
|
|
| PRK07993 |
PRK07993 |
DNA polymerase III subunit delta'; Validated |
105-165 |
6.91e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181190 [Multi-domain] Cd Length: 334 Bit Score: 44.29 E-value: 6.91e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 105 ARKGGYpcppyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRC 165
Cdd:PRK07993 104 ARLGGA-----KVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRC 159
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
44-134 |
9.39e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 41.89 E-value: 9.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALAIAYQLYG-PELYKSRVLELNASDDRGINVVRTKIKDFA-AVAVGSARKGgypcppyKIIILD 121
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNrPVFYVQLTRDTTEEDLFGRRNIDPGGASWVdGPLVRAAREG-------EIAVLD 73
|
90
....*....|...
gi 2547841212 122 EADSMTEDAQNAL 134
Cdd:pfam07728 74 EINRANPDVLNSL 86
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
60-280 |
9.91e-05 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 43.32 E-value: 9.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 60 LAIAYQLYGPELY-----KSRVLELNASDDRGINVVRTKIKDFAAVAVGSARKGgypcPP----YKIIILDEADSMT--E 128
Cdd:COG1466 3 LAPVYLLYGEEPLlideaADALRAAALAEDDGFNRTRLDGAETDWAELLDEAQT----LSlfgeRRLVIVRNAEFLKkpG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 129 DAQNALRRTMETYSKVTRFFFICNYI---SRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTIS 205
Cdd:COG1466 79 EGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 206 NGDLRRAITYLQSAARLFGSS--ISSTDLISVSGAIPE----DVVKSLLAscksGEFDVANKEVNNIIADGYP----VSQ 275
Cdd:COG1466 159 GGDLLALAQELEKLALYAGDGgtITLEDVEALVGDSAEfnvfDLADALLA----GDAARALRILRRLLAEGEEpvliLAA 234
|
....*
gi 2547841212 276 LISQF 280
Cdd:COG1466 235 LARQF 239
|
|
| PRK08699 |
PRK08699 |
DNA polymerase III subunit delta'; Validated |
46-176 |
1.46e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181538 [Multi-domain] Cd Length: 325 Bit Score: 42.94 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 46 LFYGPPGTGKTTTALAIAYQLY------------------------GPELYksRVLELNASDDRGINVVRTKIK------ 95
Cdd:PRK08699 25 LFAGKKGIGKTAFARFAAQALLcetpapghkpcgecmschlfgqgsHPDFY--EITPLSDEPENGRKLLQIKIDavreii 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 96 DFAAVavgSARKGGYpcppyKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSE 175
Cdd:PRK08699 103 DNVYL---TSVRGGL-----RVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSH 174
|
.
gi 2547841212 176 E 176
Cdd:PRK08699 175 E 175
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
27-70 |
2.26e-04 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 42.83 E-value: 2.26e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2547841212 27 EEVVRVLTTTLQTAdlPHMLFYGPPGTGKTTTALAIAYQLYGPE 70
Cdd:COG1401 208 EETLEAFLAALKTK--KNVILAGPPGTGKTYLARRLAEALGGED 249
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
45-139 |
2.38e-04 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 41.24 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQLYGPeLYKSRVLELNAsddrGIN-VVRTKIKDFAAVAVGSArkggyPCppykIIILDEA 123
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGELKVP-FLKISATEIVS----GVSgESEEKIRELFDQAISNA-----PC----IVFIDEI 102
|
90
....*....|....*.
gi 2547841212 124 DSMTEDAQNAlRRTME 139
Cdd:cd19518 103 DAITPKRESA-QREME 117
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
14-134 |
3.02e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.67 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 14 KYRPRQVKDVAHQEEVVRVLTTTLQTADLPHM-LFYGPPGTGKTTTALAIAYQL---YGP------------ELykSR-- 75
Cdd:PRK07764 8 RYRPATFAEVIGQEHVTEPLSTALDSGRINHAyLFSGPRGCGKTSSARILARSLncvEGPtstpcgecdscvAL--APgg 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 76 -----VLELNASDDRGINVVRtKIKDFAAVAVGSARkggypcppYKIIILDEADSMTEDAQNAL 134
Cdd:PRK07764 86 pgsldVTEIDAASHGGVDDAR-ELRERAFFAPAESR--------YKIFIIDEAHMVTPQGFNAL 140
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
49-66 |
3.19e-04 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 39.91 E-value: 3.19e-04
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
46-66 |
3.82e-04 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 41.92 E-value: 3.82e-04
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
188-248 |
4.26e-04 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 38.60 E-value: 4.26e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 188 EEGLSLDAQALATLSTISNGDLRRAITYLQSAArlfgssiSSTDLISVSGAIPEDVVKSLL 248
Cdd:pfam16193 2 GLKIELDDEALEALAELADGDARRALNALELAV-------LSTPPDDGGIHITLEILEEAL 55
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
45-140 |
4.43e-04 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 41.42 E-value: 4.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAY------QLYGPELYKSRVLELNASDDRGinVVRTKIKdfaavAVGSARKGGYPCPPYKII 118
Cdd:COG3598 16 TLLAGPPGTGKSFLALQLAAavaaggPWLGRRVPPGKVLYLAAEDDRG--ELRRRLK-----ALGADLGLPFADLDGRLR 88
|
90 100
....*....|....*....|...
gi 2547841212 119 ILDEADSMTEDA-QNALRRTMET 140
Cdd:COG3598 89 LLSLAGDLDDTDdLEALERAIEE 111
|
|
| DUF2075 |
pfam09848 |
Schlafen group 3, DNA/RNA helicase domain; This domain is found in at the C terminus of group ... |
43-149 |
4.46e-04 |
|
Schlafen group 3, DNA/RNA helicase domain; This domain is found in at the C terminus of group 3 Schlafen proteins from mammals, and represents the DNA/RNA helicase domain. Schlafen proteins are involved in the control of cell proliferation, induction of immune responses, and in the regulation of viral replication. These proteins inhibit DNA replication and promote cell death in response to DNA damage. They play a role in genome surveillance to kill cells with defective replication. This domain is also found in various uncharacterized prokaryotic proteins fused to a DNA helicase, GIY-YIG or PD-(D/E)XK catalytic domain or HsdR-N(terminal) domain, which are similar to AAA DNA helicase, Type III restriction enzyme ATPase, RecD and RuvB helicase.
Pssm-ID: 430875 [Multi-domain] Cd Length: 355 Bit Score: 41.50 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 43 PHMLF-YGPPGTGKTTTALAIAYQLYGPELYKSR-----------VLELNASDDRGINVVRTKIKDFAAVaVGSARKggy 110
Cdd:pfam09848 1 KAVFLvTGGPGTGKTVIGLNLFAELEDSDLGRTAvylsgnhplvlVLYEALAGDLRKKRKKSAFQRPTSF-INNLHK--- 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2547841212 111 PCPPYKIIILDEADSMTEDA--------QNALRRTMETySKVTRFFF 149
Cdd:pfam09848 77 THPHEDVVIFDEAHRLWDKSdpynnfsgPNQLKEIMKR-AKVIVFLV 122
|
|
| PRK08769 |
PRK08769 |
DNA polymerase III subunit delta'; Validated |
37-179 |
5.96e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181551 [Multi-domain] Cd Length: 319 Bit Score: 41.10 E-value: 5.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 37 LQTADLPH-MLFYGPPGTGKTTTALAIAYQLYG--------------------PELYKSRVLELNASDDRGINVVRTKIK 95
Cdd:PRK08769 20 LDAGRLGHgLLICGPEGLGKRAVALALAEHVLAsgpdpaaaqrtrqliaagthPDLQLVSFIPNRTGDKLRTEIVIEQVR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 96 DFAAVAVGSARKGgypcpPYKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFK-PLS 174
Cdd:PRK08769 100 EISQKLALTPQYG-----IAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKlPPA 174
|
....*
gi 2547841212 175 EEVMS 179
Cdd:PRK08769 175 HEALA 179
|
|
| DEXXQc_UPF1 |
cd18039 |
DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of ... |
26-91 |
8.81e-04 |
|
DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of Nonsense Transcripts, or ATP-Dependent Helicase RENT1) is an RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. It is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. It is recruited by release factors to stalled ribosomes together with the SMG1C protein kinase complex to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) located downstream from the termination codon through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Diseases associated with UPF1 include juvenile amyotrophic lateral sclerosis and epidermolysis bullosa, junctional, non-Herlitz type. UPF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350797 [Multi-domain] Cd Length: 234 Bit Score: 40.31 E-value: 8.81e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2547841212 26 QEEVVRvltTTLQTadlPHMLFYGPPGTGKTTTALAIAYQLYgpELYKSRVLELNAS-----------DDRGINVVR 91
Cdd:cd18039 6 QVDAVK---TALQR---PLSLIQGPPGTGKTVTSATIVYHLV--KQGNGPVLVCAPSnvavdqltekiHQTGLKVVR 74
|
|
| DEXXc_HELZ2-C |
cd18040 |
C-terminal DEXX-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known ... |
43-66 |
1.02e-03 |
|
C-terminal DEXX-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known as PPAR-alpha-interacting complex protein 285 or PRIC285 and PPAR-gamma DBD-interacting protein 1 or PDIP1) acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA. It belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350798 [Multi-domain] Cd Length: 271 Bit Score: 40.20 E-value: 1.02e-03
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
45-145 |
1.02e-03 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 39.02 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQ-------LYGPELYKSRVLElnasDDRGINVVRTKIKDFAavavgsarkggyPCppykI 117
Cdd:cd19529 30 ILLYGPPGTGKTLLAKAVATEsnanfisVKGPELLSKWVGE----SEKAIREIFRKARQVA------------PC----V 89
|
90 100
....*....|....*....|....*...
gi 2547841212 118 IILDEADSMtedaqnALRRTMETYSKVT 145
Cdd:cd19529 90 IFFDEIDSI------APRRGTTGDSGVT 111
|
|
| AAA_11 |
pfam13086 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
46-77 |
1.26e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 404072 [Multi-domain] Cd Length: 248 Bit Score: 39.63 E-value: 1.26e-03
10 20 30
....*....|....*....|....*....|....*.
gi 2547841212 46 LFYGPPGTGKTTTALAIAYQLYGPEL----YKSRVL 77
Cdd:pfam13086 17 LIQGPPGTGKTTTIVELIRQLLSYPAtsaaAGPRIL 52
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
45-126 |
1.39e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 38.65 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIA-------YQLYGPELYKSRVLELNASDDRGINVVRtkikdfaavavgSARkggyPCppykI 117
Cdd:cd19527 29 ILLYGPPGTGKTLLAKAIAtecslnfLSVKGPELINMYIGESEANVREVFQKAR------------DAK----PC----V 88
|
....*....
gi 2547841212 118 IILDEADSM 126
Cdd:cd19527 89 IFFDELDSL 97
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
46-78 |
1.43e-03 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 38.81 E-value: 1.43e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 2547841212 46 LFYGPPGTGKTTTALAIA-------YQLYGPELYKSRVLE 78
Cdd:cd19503 38 LLHGPPGTGKTLLARAVAneaganfLSISGPSIVSKYLGE 77
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
186-222 |
1.77e-03 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 36.46 E-value: 1.77e-03
10 20 30
....*....|....*....|....*....|....*..
gi 2547841212 186 CNEEGLSLDAQALATLSTISNGDLRRAITYLQSAARL 222
Cdd:cd18139 20 GGDRKVTIDDEALELLAEAADGDARSALNLLELAVLS 56
|
|
| PRK07132 |
PRK07132 |
DNA polymerase III subunit delta'; Validated |
115-171 |
1.98e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180855 [Multi-domain] Cd Length: 299 Bit Score: 39.32 E-value: 1.98e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2547841212 115 YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFK 171
Cdd:PRK07132 91 KKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVK 147
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
45-136 |
1.99e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 38.85 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALaiayqlygpELYKSRVLELNAS-----DDRGINVV-RTKIKDFAAVAVGSARKGGypcPPYKII 118
Cdd:pfam13479 5 ILIYGPSGIGKTTFAK---------TLPKPLFLDTEKGskaldGDRFPDIViRDSWQDFLDAIDELTAAEL---ADYKTI 72
|
90
....*....|....*...
gi 2547841212 119 ILDEADSMTEDAQNALRR 136
Cdd:pfam13479 73 VIDTVDWLERLCLAYICK 90
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
21-81 |
2.30e-03 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 38.67 E-value: 2.30e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2547841212 21 KDVAHQEEVVRVLTttLQTADLPHMLFYGPPGTGKTTTALAIAYQLygPELYKSRVLELNA 81
Cdd:pfam01078 3 ADVKGQEQAKRALE--IAAAGGHNLLMIGPPGSGKTMLAKRLPGIL--PPLTEAEALEVTA 59
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
24-77 |
2.39e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 39.62 E-value: 2.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 24 AHQEEVVRVLTTTLQTADlPHMLFYGPPGTGKTTTALAIAYQLYGPElyksRVL 77
Cdd:COG1061 83 PYQQEALEALLAALERGG-GRGLVVAPTGTGKTVLALALAAELLRGK----RVL 131
|
|
| DEXXQc_SMUBP2 |
cd18044 |
DEXXQ-box helicase domain of SMUBP2; SMUBP2 (also called immunoglobulin mu-binding protein 2, ... |
26-91 |
2.95e-03 |
|
DEXXQ-box helicase domain of SMUBP2; SMUBP2 (also called immunoglobulin mu-binding protein 2, or IGHMBP2) is a 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. It is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence (5'-GGGCT-3') related to the immunoglobulin mu chain switch region. The IGHMBP2 gene is responsible for Charcot-Marie-Tooth disease (CMT) type 2S and spinal muscular atrophy with respiratory distress type 1 (SMARD1). It is also thought to play a role in frontotemporal dementia (FTD) with amyotrophic lateral sclerosis (ALS) and major depressive disorder (MDD). SMUBP2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350802 [Multi-domain] Cd Length: 191 Bit Score: 38.36 E-value: 2.95e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2547841212 26 QEEVVRvltTTLQTADLphMLFYGPPGTGKTTTALAIAYQLYGPelyKSRVLELNASD-----------DRGINVVR 91
Cdd:cd18044 6 QKEAVK---FALSQKDV--ALIHGPPGTGKTTTVVEIILQAVKR---GEKVLACAPSNiavdnlverlvALKVKVVR 74
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
26-69 |
3.61e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 38.61 E-value: 3.61e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2547841212 26 QEEVVRVLTTTLqTADLpHMLFYGPPGTGKTTTALAIAYQLYGP 69
Cdd:COG0714 17 QEELIELVLIAL-LAGG-HLLLEGVPGVGKTTLAKALARALGLP 58
|
|
| RecA-like_ATAD3-like |
cd19512 |
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ... |
44-63 |
3.85e-03 |
|
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410920 [Multi-domain] Cd Length: 150 Bit Score: 37.51 E-value: 3.85e-03
|
| DEXXQc_Mov10L1 |
cd18078 |
DEXXQ-box helicase domain of Mov10L1; Moloney leukemia virus 10-like protein 1 (Mov10L1) binds ... |
42-107 |
4.23e-03 |
|
DEXXQ-box helicase domain of Mov10L1; Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. Mov10L1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350836 [Multi-domain] Cd Length: 230 Bit Score: 38.12 E-value: 4.23e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2547841212 42 LPHMLFyGPPGTGKTTTALAIAYQLYgPELYKSRVLELNASDDrGINVVRTKIKDFAAVAVGSARK 107
Cdd:cd18078 21 LPYILF-GPPGTGKTVTIIEAILQVV-YNLPRSRILVCAPSNS-AADLVTSRLHESKVLKPGDMVR 83
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
44-229 |
4.34e-03 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 38.81 E-value: 4.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 44 HMLFYGPPGTGKTTTALA-IAYQLygpelyksrvlelnasdDRGINVVRTKIK-DFAAVAVGSARKGGypcppYKIIILD 121
Cdd:COG3505 1 HVLVIGPTGSGKTVGLVIpNLTQL-----------------ARGESVVVTDPKgDLAELTAGFRRRAG-----YDVYVFD 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 122 EADSMTEDAQNALRRtMETYSKVTRFfficnyISRIIEPLASRCAK--FrFKPLSEEVMSNRILHICNEEGLSLD----- 194
Cdd:COG3505 59 PFDPERSHRWNPLDE-IRDPADAQEL------AEALIPALGGGGGGdpF-WREAARALLAALILALAEEGRRTLAdvyrl 130
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2547841212 195 --------AQALATLSTISNGDLRRAIT-YLQSAARLFGSSISS 229
Cdd:COG3505 131 lsepeeelRELLEALPESPHPPVADTLAaFLNAAEKTRSSVLST 174
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
45-140 |
4.45e-03 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 37.54 E-value: 4.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 45 MLFYGPPGTGKTTTALAIAYQLYGPELYKSRVlELNASDDRGiNVVRTKikdFAAVAVGSARKGGYPCP-----PYKIII 119
Cdd:cd19499 44 FLFLGPTGVGKTELAKALAELLFGDEDNLIRI-DMSEYMEKH-SVSRLI---GAPPGYVGYTEGGQLTEavrrkPYSVVL 118
|
90 100
....*....|....*....|.
gi 2547841212 120 LDEADSMTEDAQNALRRTMET 140
Cdd:cd19499 119 LDEIEKAHPDVQNLLLQVLDD 139
|
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
46-174 |
4.94e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 36.80 E-value: 4.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 46 LFYGPPGTGKTTtalaIAYQLYGPELYKSRVLELNASDDRginvvRTKIKDFAAVAVgsARKGGYPCPPYkiIILDEAdS 125
Cdd:pfam13173 6 VITGPRQVGKTT----LLLQLIKELLPPENILYINLDDPR-----LLKLADFELLEL--FLELLYPGKTY--LFLDEI-Q 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2547841212 126 MTEDAQNALRRTMETYSKVtrFFFIC---NYI--SRIIEPLASRCAKFRFKPLS 174
Cdd:pfam13173 72 RVPDWELALKRLYDDGPNG--RVILTgssALLlsKEIAESLAGRVVVIELYPLS 123
|
|
| DEXXQc_SETX |
cd18042 |
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in ... |
49-95 |
4.97e-03 |
|
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in transcription, neurogenesis, and antiviral response. SEXT is an R-loop-associated protein that is thought to function as an RNA/DNA helicase. R-loops consist of RNA/DNA hybrids, formed during transcription when nascent RNA hybridizes to the DNA template strand, displacing the non-template DNA strand. Mutations in SETX are linked to two neurodegenerative disorders: ataxia with oculomotor apraxia type 2 (AOA2) and amyotrophic lateral sclerosis type 4 (ALS4). S. cerevisiae homolog splicing endonuclease 1 (Sen1) is an exclusively nuclear protein, important for nucleolar organization. S. cerevisiae Sen1 and its ortholog, the Schizosaccharomyces pombe Sen1, share conserved domains and belong to the family I class of helicases. Both proteins translocate 5' to 3' and unwind both DNA and RNA duplexes and also RNA/DNA hybrids in vitro. SETX is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438712 [Multi-domain] Cd Length: 218 Bit Score: 37.96 E-value: 4.97e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 2547841212 49 GPPGTGKTTTALAIAYQLYG--PELYKSRVLELNASDDRGINVVRTKIK 95
Cdd:cd18042 24 GPPGTGKTKTIVGILSVLLAgkYRKYYEKVKKKLRKLQRNLNNKKKKNR 72
|
|
| VirB4 |
COG3451 |
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ... |
41-140 |
5.47e-03 |
|
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain] Cd Length: 546 Bit Score: 38.39 E-value: 5.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 41 DLPHMLFYGPPGTGKTTTALAIAYQL--YGPEL--------YKS-------RVLELNASDDRGIN--------VVRTKIK 95
Cdd:COG3451 203 DNGNTLILGPSGSGKSFLLKLLLLQLlrYGARIvifdpggsYEIlvralggTYIDLSPGSPTGLNpfdledteEKRDFLL 282
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2547841212 96 DFAAVAVGSarkGGYPCPPYKIIILDEA-DSMTEDAQNALRRTMET 140
Cdd:COG3451 283 ELLELLLGR---EGEPLTPEERAAIDRAvRALYRRADPEERTTLSD 325
|
|
| COG4889 |
COG4889 |
Predicted helicase [General function prediction only]; |
13-77 |
5.60e-03 |
|
Predicted helicase [General function prediction only];
Pssm-ID: 443917 [Multi-domain] Cd Length: 1571 Bit Score: 38.78 E-value: 5.60e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 13 EKYRPRQvkdvaHQEEVVRVLTTTLQTADLPHMLFygPPGTGKTTTALAIAYQLYGPelyKSRVL 77
Cdd:COG4889 166 AKKTLRP-----HQQEAIEAVLAGFKTHDRGKLIM--ACGTGKTFTSLRIAEELAGK---GGRVL 220
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
27-74 |
5.71e-03 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 38.49 E-value: 5.71e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2547841212 27 EEVVRVL----TTTLQTADLPH-MLFYGPPGTGKTTTALAIAYQLYGPELYKS 74
Cdd:CHL00176 196 EEVVSFLkkpeRFTAVGAKIPKgVLLVGPPGTGKTLLAKAIAGEAEVPFFSIS 248
|
|
| TIP49 |
COG1224 |
DNA helicase TIP49, TBP-interacting protein [Transcription]; |
46-77 |
6.01e-03 |
|
DNA helicase TIP49, TBP-interacting protein [Transcription];
Pssm-ID: 440837 [Multi-domain] Cd Length: 452 Bit Score: 38.41 E-value: 6.01e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2547841212 46 LFYGPPGTGKTTTALAIAYQL--------------YGPELYKSRVL 77
Cdd:COG1224 68 LIVGPPGTGKTALAVAIARELgedtpfvaisgseiYSAELKKTEFL 113
|
|
| cbbX |
CHL00181 |
CbbX; Provisional |
44-67 |
7.43e-03 |
|
CbbX; Provisional
Pssm-ID: 177083 [Multi-domain] Cd Length: 287 Bit Score: 37.77 E-value: 7.43e-03
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
46-134 |
7.82e-03 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 37.45 E-value: 7.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2547841212 46 LFYGPPGTGKTTTALAIAYQL----------YGPELyksrVLELNASddRGINVVRTKIKDFAAvavgsarkggypcppY 115
Cdd:COG1484 103 ILLGPPGTGKTHLAIALGHEAcragyrvrftTAPDL----VNELKEA--RADGRLERLLKRLAK---------------V 161
|
90 100
....*....|....*....|.
gi 2547841212 116 KIIILDE--ADSMTEDAQNAL 134
Cdd:COG1484 162 DLLILDElgYLPLDAEGAELL 182
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
21-63 |
8.70e-03 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 36.44 E-value: 8.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 2547841212 21 KDVAHQEE-------VVRVLTTTLQTADL----PH-MLFYGPPGTGKTTTALAIA 63
Cdd:cd19501 4 KDVAGCEEakeelkeVVEFLKNPEKFTKLgakiPKgVLLVGPPGTGKTLLAKAVA 58
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
46-65 |
9.54e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 37.50 E-value: 9.54e-03
|
| |
