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Conserved domains on  [gi|2778098833|ref|NP_001418998|]
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IQ domain-containing protein E isoform 9 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cast super family cl37807
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 31-374 8.89e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


The actual alignment was detected with superfamily member pfam10174:

Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 55.60  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDlmrTKLRRLEEENSRKDRQIEQLLDPGRGPDfvRTLAEKKPDTGWVITGLKQRIF 110
Cdd:pfam10174 411 RDKDKQLAGLKERVKSLQTDSSNTD---TALTTLEEALSEKERIIERLKEQRERED--RERLEELESLKKENKDLKEKVS 485

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 111 RLEQQCKEKDSTINKLQTDM---------KTTNLEEMRIAMETYYEEIHRLQTLLasseatgkKPILEKKMGVKRQKKMS 181
Cdd:pfam10174 486 ALQPELTEKESSLIDLKEHAsslassglkKDSKLKSLEIAVEQKKEECSKLENQL--------KKAHNAEEAVRTNPEIN 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 182 SALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDwskprllRRIAELEKKVSSSESPKNSASELVKPNPVVP 261
Cdd:pfam10174 558 DRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD-------KKIAELESLTLRQMKEQNKKVANIKHGQQEM 630

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 262 SPSNISvqkQLKGDQSKEDQPKVDPSEDQ-EHLQGTVKTLREELSALQEQLLgkdlEMKQMLQSK--------IDLEKEL 332
Cdd:pfam10174 631 KKKGAQ---LLEEARRREDNLADNSQQLQlEELMGALEKTRQELDATKARLS----STQQSLAEKdghltnlrAERRKQL 703

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 333 ETAREGEKE------------------SQEREQALREEVEALTKKCQELEEAKRQETQER 374
Cdd:pfam10174 704 EEILEMKQEallaaisekdaniallelSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
IQ smart00015
Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln ...
 451-471 2.49e-03

Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln residues.


:

Pssm-ID: 197470 [Multi-domain]  Cd Length: 23  Bit Score: 35.76  E-value: 2.49e-03
                           10        20
                   ....*....|....*....|.
gi 2778098833  451 LDEAATVLQAAFRGHLARSKL 471
Cdd:smart00015   2 LTRAAIIIQAAWRGYLARKRY 22
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 31-374 8.89e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 55.60  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDlmrTKLRRLEEENSRKDRQIEQLLDPGRGPDfvRTLAEKKPDTGWVITGLKQRIF 110
Cdd:pfam10174 411 RDKDKQLAGLKERVKSLQTDSSNTD---TALTTLEEALSEKERIIERLKEQRERED--RERLEELESLKKENKDLKEKVS 485

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 111 RLEQQCKEKDSTINKLQTDM---------KTTNLEEMRIAMETYYEEIHRLQTLLasseatgkKPILEKKMGVKRQKKMS 181
Cdd:pfam10174 486 ALQPELTEKESSLIDLKEHAsslassglkKDSKLKSLEIAVEQKKEECSKLENQL--------KKAHNAEEAVRTNPEIN 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 182 SALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDwskprllRRIAELEKKVSSSESPKNSASELVKPNPVVP 261
Cdd:pfam10174 558 DRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD-------KKIAELESLTLRQMKEQNKKVANIKHGQQEM 630

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 262 SPSNISvqkQLKGDQSKEDQPKVDPSEDQ-EHLQGTVKTLREELSALQEQLLgkdlEMKQMLQSK--------IDLEKEL 332
Cdd:pfam10174 631 KKKGAQ---LLEEARRREDNLADNSQQLQlEELMGALEKTRQELDATKARLS----STQQSLAEKdghltnlrAERRKQL 703

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 333 ETAREGEKE------------------SQEREQALREEVEALTKKCQELEEAKRQETQER 374
Cdd:pfam10174 704 EEILEMKQEallaaisekdaniallelSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 105-376 9.62e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 9.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 105 LKQRIFRLEQQCKEKDSTINKLQTDM--KTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPILEKKMGVKRQKKMSS 182
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELaeLEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 183 ALLNLTRSVQELTEENQSLKEDLDRMLSnsptvskikgyvdwSKPRLLRRIAELEKKVSSSESPKNSASELVKpnpvvps 262
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEE--------------ELEEAEEELEEAEAELAEAEEALLEAEAELA------- 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 263 pSNISVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKES 342
Cdd:COG1196   376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2778098833 343 QEREQALREEVEALTKKCQELEEAKRQETQERQD 376
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 84-392 3.43e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 3.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   84 GPDFVRTLAEKKPDTGwvITGLKQRIFRLEQQCKEKDSTINKLQTdmkttNLEEMRIAMETYYEEIHRLQTLLASSEATG 163
Cdd:TIGR02168  656 RPGGVITGGSAKTNSS--ILERRREIEELEEKIEELEEKIAELEK-----ALAELRKELEELEEELEQLRKELEELSRQI 728

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  164 KKPILEKKMGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDWSKPRLLRRIAELEKKVSSS 243
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  244 ESPKNSASELV--KPNPVVPSPSNISVQKQLKGDQSKEdqpKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQM 321
Cdd:TIGR02168  809 RAELTLLNEEAanLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2778098833  322 LQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELE------EAKRQETQERQDSFIAMTHEAHPEVHAP 392
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrleglEVRIDNLQERLSEEYSLTLEEAEALENK 962
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
105-366 2.47e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 105 LKQRIFRLEQQCKEKDSTINKL-----QTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEatGKKPILEKKMG--VKRQ 177
Cdd:PRK03918  191 IEELIKEKEKELEEVLREINEIsselpELREELEKLEKEVKELEELKEEIEELEKELESLE--GSKRKLEEKIRelEERI 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 178 KKMSSALLNLTRSVQELTE------ENQSLKEDLDRMLSNSPTVSKIKGyvdwskpRLLRRIAELEKKVSSSESPKNSAS 251
Cdd:PRK03918  269 EELKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLS-------RLEEEINGIEERIKELEEKEERLE 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 252 ELVKpnpvvpspsnisvqkqlkgdQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEmkqmlqskiDLEKE 331
Cdd:PRK03918  342 ELKK--------------------KLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE---------KLEKE 392

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2778098833 332 LETAREGEKESQEREQALREEVEALTKKCQELEEA 366
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427
IQ smart00015
Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln ...
 451-471 2.49e-03

Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln residues.


Pssm-ID: 197470 [Multi-domain]  Cd Length: 23  Bit Score: 35.76  E-value: 2.49e-03
                           10        20
                   ....*....|....*....|.
gi 2778098833  451 LDEAATVLQAAFRGHLARSKL 471
Cdd:smart00015   2 LTRAAIIIQAAWRGYLARKRY 22
IQ pfam00612
IQ calmodulin-binding motif; Calmodulin-binding motif.
 453-471 4.75e-03

IQ calmodulin-binding motif; Calmodulin-binding motif.


Pssm-ID: 459869  Cd Length: 21  Bit Score: 34.99  E-value: 4.75e-03
                          10
                  ....*....|....*....
gi 2778098833 453 EAATVLQAAFRGHLARSKL 471
Cdd:pfam00612   2 KAAIKIQAAWRGYLARKRY 20
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 31-374 8.89e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 55.60  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDlmrTKLRRLEEENSRKDRQIEQLLDPGRGPDfvRTLAEKKPDTGWVITGLKQRIF 110
Cdd:pfam10174 411 RDKDKQLAGLKERVKSLQTDSSNTD---TALTTLEEALSEKERIIERLKEQRERED--RERLEELESLKKENKDLKEKVS 485

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 111 RLEQQCKEKDSTINKLQTDM---------KTTNLEEMRIAMETYYEEIHRLQTLLasseatgkKPILEKKMGVKRQKKMS 181
Cdd:pfam10174 486 ALQPELTEKESSLIDLKEHAsslassglkKDSKLKSLEIAVEQKKEECSKLENQL--------KKAHNAEEAVRTNPEIN 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 182 SALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDwskprllRRIAELEKKVSSSESPKNSASELVKPNPVVP 261
Cdd:pfam10174 558 DRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD-------KKIAELESLTLRQMKEQNKKVANIKHGQQEM 630

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 262 SPSNISvqkQLKGDQSKEDQPKVDPSEDQ-EHLQGTVKTLREELSALQEQLLgkdlEMKQMLQSK--------IDLEKEL 332
Cdd:pfam10174 631 KKKGAQ---LLEEARRREDNLADNSQQLQlEELMGALEKTRQELDATKARLS----STQQSLAEKdghltnlrAERRKQL 703

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 333 ETAREGEKE------------------SQEREQALREEVEALTKKCQELEEAKRQETQER 374
Cdd:pfam10174 704 EEILEMKQEallaaisekdaniallelSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 105-376 9.62e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 9.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 105 LKQRIFRLEQQCKEKDSTINKLQTDM--KTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPILEKKMGVKRQKKMSS 182
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELaeLEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 183 ALLNLTRSVQELTEENQSLKEDLDRMLSnsptvskikgyvdwSKPRLLRRIAELEKKVSSSESPKNSASELVKpnpvvps 262
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEE--------------ELEEAEEELEEAEAELAEAEEALLEAEAELA------- 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 263 pSNISVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKES 342
Cdd:COG1196   376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2778098833 343 QEREQALREEVEALTKKCQELEEAKRQETQERQD 376
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 84-392 3.43e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 3.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   84 GPDFVRTLAEKKPDTGwvITGLKQRIFRLEQQCKEKDSTINKLQTdmkttNLEEMRIAMETYYEEIHRLQTLLASSEATG 163
Cdd:TIGR02168  656 RPGGVITGGSAKTNSS--ILERRREIEELEEKIEELEEKIAELEK-----ALAELRKELEELEEELEQLRKELEELSRQI 728

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  164 KKPILEKKMGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDWSKPRLLRRIAELEKKVSSS 243
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  244 ESPKNSASELV--KPNPVVPSPSNISVQKQLKGDQSKEdqpKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQM 321
Cdd:TIGR02168  809 RAELTLLNEEAanLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2778098833  322 LQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELE------EAKRQETQERQDSFIAMTHEAHPEVHAP 392
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrleglEVRIDNLQERLSEEYSLTLEEAEALENK 962
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 28-375 3.56e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   28 SVYREKEDMY-DEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPGRGPDFVRTLAEKKPDTGW-VITGL 105
Cdd:pfam15921  331 SELREAKRMYeDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWdRDTGN 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  106 KQRIFRLEQQCKEKDSTINKLQTDMKTT------NLEEMRIAMETYYEEIHRLQTLLASSEATgkKPILEKKMGVKRQKK 179
Cdd:pfam15921  411 SITIDHLRRELDDRNMEVQRLEALLKAMksecqgQMERQMAAIQGKNESLEKVSSLTAQLEST--KEMLRKVVEELTAKK 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  180 MSsaLLNLTRSVQELTeenQSLKEDLDRMLSNSPTVSKIKGYVDWskprllrRIAELEKKVSSSESPKNSASE------- 252
Cdd:pfam15921  489 MT--LESSERTVSDLT---ASLQEKERAIEATNAEITKLRSRVDL-------KLQELQHLKNEGDHLRNVQTEcealklq 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  253 LVKPNPVVPS-PSNISVQKQLKGDQSKEDQPKvdpSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKE 331
Cdd:pfam15921  557 MAEKDKVIEIlRQQIENMTQLVGQHGRTAGAM---QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELE 633

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2778098833  332 --------LETAREGEKESQEREQAL------REEVEALTKKCQELEEAKRQETQERQ 375
Cdd:pfam15921  634 kvklvnagSERLRAVKDIKQERDQLLnevktsRNELNSLSEDYEVLKRNFRNKSEEME 691
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 24-380 4.90e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 4.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   24 VSGTSVY-REKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEEN---------SRKDRQIEQLLDPGRgpdfVRTLAE 93
Cdd:TIGR02169  162 IAGVAEFdRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERekaeryqalLKEKREYEGYELLKE----KEALER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   94 KKPDTGWVITGLKQRIFRLEQQCKEKDSTINKLQTDMKTTNLEEMRIAMETYY---EEIHRLQTLLASSEATGKKPILEK 170
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLrvkEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  171 KMGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDrmlsnsptvsKIKGYVDWSKPR---LLRRIAELEKKvsSSESPK 247
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD----------KLTEEYAELKEEledLRAELEEVDKE--FAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  248 NSASELVKPNPVvpspsnISVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQmlqskid 327
Cdd:TIGR02169  386 ELKDYREKLEKL------KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK------- 452

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2778098833  328 LEKELETAREGEKESQEREQALREEVEALTKKCQELE------EAKRQETQERQDSFIA 380
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQrelaeaEAQARASEERVRGGRA 511
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-388 1.05e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAregEKESQEREQALREEVEALTKKCQELEEAK 367
Cdd:COG1196   309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEELEELA 385

                          90       100
                  ....*....|....*....|.
gi 2778098833 368 RQETQERQDSFIAMTHEAHPE 388
Cdd:COG1196   386 EELLEALRAAAELAAQLEELE 406
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 287-378 1.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 287 SEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKcQELEEA 366
Cdd:COG1196   294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA-LLEAEA 372

                          90
                  ....*....|..
gi 2778098833 367 KRQETQERQDSF 378
Cdd:COG1196   373 ELAEAEEELEEL 384
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 37-369 2.07e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 2.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   37 YDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDpgrgpdFVRTLAEKKPDTGWVITGLKQRIFRLEQQC 116
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL------EVSELEEEIEELQKELYALANEISRLEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  117 KEKDSTINKLQTDMKTTN--LEEMRIAMETYYEEIHRLQTLLASSEAtgkkpilEKKMGVKRQKKMSSALLNLTRSVQEL 194
Cdd:TIGR02168  305 QILRERLANLERQLEELEaqLEELESKLDELAEELAELEEKLEELKE-------ELESLEAELEELEAELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  195 TEENQSLKEDLDRmlsnsptvskikgyvdwskprLLRRIAELEKKVSSSESPKNSASElvkpnpvvpspsniSVQKQlkg 274
Cdd:TIGR02168  378 EEQLETLRSKVAQ---------------------LELQIASLNNEIERLEARLERLED--------------RRERL--- 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  275 DQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLlgkdlemkqmlqskIDLEKELETAREGEKESQEREQALREEVE 354
Cdd:TIGR02168  420 QQEIEELLKKLEEAELKELQAELEELEEELEELQEEL--------------ERLEEALEELREELEEAEQALDAAERELA 485

                          330
                   ....*....|....*
gi 2778098833  355 ALTKKCQELEEAKRQ 369
Cdd:TIGR02168  486 QLQARLDSLERLQEN 500
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 102-375 2.24e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 102 ITGLKQRIFRLEQQCKEKDSTINKLQTDMKTTNLEEmriamETYYEEIHRLQTLLASSEATGKKPILEKKMGVKRQKKMS 181
Cdd:TIGR04523  77 IKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI-----KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKE 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 182 SALLNLTRSVQELTEENQSLKEDLDRMLSNsptVSKIKGYVDWSKPRLLR---RIAELEKKVSSSESPKNSASELVKPNp 258
Cdd:TIGR04523 152 KELEKLNNKYNDLKKQKEELENELNLLEKE---KLNIQKNIDKIKNKLLKlelLLSNLKKKIQKNKSLESQISELKKQN- 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 259 vvpspSNISVQKQLKGDQSKEDQPKVDPSEDQehlqgtVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAR-E 337
Cdd:TIGR04523 228 -----NQLKDNIEKKQQEINEKTTEISNTQTQ------LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKsE 296

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2778098833 338 GEKESQEREQALREEV-EALTKKCQELEEAKRQETQERQ 375
Cdd:TIGR04523 297 ISDLNNQKEQDWNKELkSELKNQEKKLEEIQNQISQNNK 335
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 31-376 3.92e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 3.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   31 REKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQI-EQLLDPGRGPDFVRTLAEKkpdtgwvITGLKQRI 109
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIsALRKDLARLEAEVEQLEER-------IAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  110 FRLEQQCKEKDSTINKLQtdmktTNLEEMRIAMETYYEEIHRLQTLLASSEatgkkpilekkmgvkrqkkmsSALLNLTR 189
Cdd:TIGR02168  757 TELEAEIEELEERLEEAE-----EELAEAEAEIEELEAQIEQLKEELKALR---------------------EALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  190 SVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDWSKPRLLRRIAELEKKVSSSESPKNSASELVKpnpvvpSPSNISVQ 269
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE------ALLNERAS 884

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  270 KQLKGDQSKEDQPKVdpSEDQEHLQGTVKTLREELSALQEQL--LGKDLE-MKQMLQSKID-----LEKELETAREGEKE 341
Cdd:TIGR02168  885 LEEALALLRSELEEL--SEELRELESKRSELRRELEELREKLaqLELRLEgLEVRIDNLQErlseeYSLTLEEAEALENK 962

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2778098833  342 SQEREQALREEVEALTKKCQEL--------EEAkrQETQERQD 376
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELgpvnlaaiEEY--EELKERYD 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 107-385 4.23e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 4.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  107 QRIFRLEQQCKEKDSTINKLQTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEAtgKKPILEKKMGVKRQKKMS--SAL 184
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE--KLEELRLEVSELEEEIEElqKEL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  185 LNLTRSVQELTEENQSLKEDLDRmlsnsptvskikgyVDWSKPRLLRRIAELEKKvsssespKNSASElvkpnpvvpsps 264
Cdd:TIGR02168  291 YALANEISRLEQQKQILRERLAN--------------LERQLEELEAQLEELESK-------LDELAE------------ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  265 nisvQKQLKGDQSKEDQPKVDP-SEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQ 343
Cdd:TIGR02168  338 ----ELAELEEKLEELKEELESlEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2778098833  344 EREQALREEVEALTKKcqeLEEAKRQETQERQDSFIAMTHEA 385
Cdd:TIGR02168  414 DRRERLQQEIEELLKK---LEEAELKELQAELEELEEELEEL 452
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 32-378 7.49e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 7.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833   32 EKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPGRGPDFVRTLAEKKPDTGWV-ITGLKQRIF 110
Cdd:TIGR02168  713 ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAeIEELEAQIE 792

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  111 RLEQQCKEKDSTINKLQTDMKTTNleemriametyyEEIHRLQTLLASSEATGKKPILEKKMGVKRQKKMSSALLNLTRS 190
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLN------------EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  191 VQELTEENQSLKEDLDRmlsnsptVSKIKGYVDWSKPRLLRRIAELEKKVSSSESpknsaselvkpnpvvpspsnisVQK 270
Cdd:TIGR02168  861 IEELEELIEELESELEA-------LLNERASLEEALALLRSELEELSEELRELES----------------------KRS 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  271 QLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSK--------IDLEKELE-------TA 335
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDeeearrrlKRLENKIKelgpvnlAA 991

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2778098833  336 REGEKESQEREQALREEVEALTKKCQELEEAKRQ---ETQER-QDSF 378
Cdd:TIGR02168  992 IEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEidrEARERfKDTF 1038
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 32-375 9.24e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.25  E-value: 9.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  32 EKEDMYDEIIELKKSLhmQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDpgrgpdfvrTLAE--KKPDTGWVITGLKQRI 109
Cdd:COG5185   250 QTSDKLEKLVEQNTDL--RLEKLGENAESSKRLNENANNLIKQFENTKE---------KIAEytKSIDIKKATESLEEQL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 110 FRLEqqcKEKDSTINKLQTDMKTTNLEemriametyyEEIHRLQTLLASSEATGKKPILEKKMGV---KRQKKMSSALLN 186
Cdd:COG5185   319 AAAE---AEQELEESKRETETGIQNLT----------AEIEQGQESLTENLEAIKEEIENIVGEVelsKSSEELDSFKDT 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 187 LTRSVQELTEENQSLKEDLDRMLSnspTVSKIKGYVDWSKPRLLRRIAELEKKVS-SSESPKNSASELVKPNPVVPSPSN 265
Cdd:COG5185   386 IESTKESLDEIPQNQRGYAQEILA---TLEDTLKAADRQIEELQRQIEQATSSNEeVSKLLNELISELNKVMREADEESQ 462

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 266 ISVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELsalqEQLLGKDLEMKQMLQSKIDLEKELETAREGEkESQER 345
Cdd:COG5185   463 SRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATL----EKLRAKLERQLEGVRSKLDQVAESLKDFMRA-RGYAH 537

                         330       340       350
                  ....*....|....*....|....*....|
gi 2778098833 346 EQALREEVEALTKKCQELEEAKRQETQERQ 375
Cdd:COG5185   538 ILALENLIPASELIQASNAKTDGQAANLRT 567
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 31-365 9.50e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 9.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPgrgpdfVRTLAEKKPDTGWVITGLKQRIF 110
Cdd:TIGR04523 321 KKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNE------IEKLKKENQSYKQEIKNLESQIN 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 111 RLEQQCKEKDSTINKLQTDMKTTNLEEmriamETYYEEIHRLQTLLASSEATGKKpiLEKKMGVKRQKkmssallnltrs 190
Cdd:TIGR04523 395 DLESKIQNQEKLNQQKDEQIKKLQQEK-----ELLEKEIERLKETIIKNNSEIKD--LTNQDSVKELI------------ 455

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 191 VQELTEENQSLKEDLDrMLSNSptVSKIKGYVDWSKPRLLRRIAELEKKVSSSESPKNSASELVKPNPvvpspSNISVQK 270
Cdd:TIGR04523 456 IKNLDNTRESLETQLK-VLSRS--INKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS-----SLKEKIE 527

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 271 QLKGDQSKEDQpKVDPSEDQehlqgtVKTLREEL--SALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQA 348
Cdd:TIGR04523 528 KLESEKKEKES-KISDLEDE------LNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                         330
                  ....*....|....*..
gi 2778098833 349 LREEVEALTKKCQELEE 365
Cdd:TIGR04523 601 LIKEIEEKEKKISSLEK 617
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 31-379 1.00e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQlldpgrgpdfVRTLAEKkpdtgwvITGLKQRIF 110
Cdd:TIGR04523 166 KQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQK----------NKSLESQ-------ISELKKQNN 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 111 RLEQQCKEKDSTINKLQTDMKTTNlEEMRIAMETYYEEIHRLQTLLASSEATGKKpILEKKMGVKRQKKMSSALLN---- 186
Cdd:TIGR04523 229 QLKDNIEKKQQEINEKTTEISNTQ-TQLNQLKDEQNKIKKQLSEKQKELEQNNKK-IKELEKQLNQLKSEISDLNNqkeq 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 187 -LTRSVQELTEENQSLKEDLDRMLSNS--------PTVSKIKGYVDWSKPRLLRRIAELEKKVSSSESPKNSASELVKPN 257
Cdd:TIGR04523 307 dWNKELKSELKNQEKKLEEIQNQISQNnkiisqlnEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEI 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 258 PVVPSPSNI---SVQKQLKGDQSKEDQPKVDPSE------DQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDL 328
Cdd:TIGR04523 387 KNLESQINDlesKIQNQEKLNQQKDEQIKKLQQEkellekEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL 466

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2778098833 329 EKELET-AREGEKESQEREQALRE------EVEALTKKCQELEEaKRQETQERQDSFI 379
Cdd:TIGR04523 467 ETQLKVlSRSINKIKQNLEQKQKElkskekELKKLNEEKKELEE-KVKDLTKKISSLK 523
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
288-374 1.08e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQL-LGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEA 366
Cdd:COG4717   163 EELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242


                  ....*...
gi 2778098833 367 KRQETQER 374
Cdd:COG4717   243 ERLKEARL 250
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 298-376 1.14e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 1.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2778098833 298 KTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAKRQETQERQD 376
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 186-384 1.14e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  186 NLTRSVQELTEENQSLKEDLDrmlsnspTVSKIKGYVDWSKPRLLRRIAELEKKVSSSESPKNSASE-LVKPNPVVPSPS 264
Cdd:pfam01576  374 NLEKAKQALESENAELQAELR-------TLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEkLSKLQSELESVS 446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  265 NISVQKQLKGDQSKEDQPKVDPS--EDQEHLQ----------GTVKTLREELSALQEQL---------LGKDLEM--KQM 321
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQlqDTQELLQeetrqklnlsTRLRQLEDERNSLQEQLeeeeeakrnVERQLSTlqAQL 526

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2778098833  322 LQSKIDLEKE---LETAREGEKESQEREQALREEVEALTKKCQELEEAKRQETQERQDSFIAMTHE 384
Cdd:pfam01576  527 SDMKKKLEEDagtLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ 592
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 102-376 1.28e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 102 ITGLKQRIFRLEQQCKEKDSTINKLQTDM--KTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPILEKKMGVKRQKK 179
Cdd:TIGR04523 337 ISQLNEQISQLKKELTNSESENSEKQRELeeKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKK 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 180 MSSALLNLTRSVQELTEENQSLKEDLDRmLSNSPTVSKIKgyvdwsKPRLLRRIAELEKKVSS-SESPKNSASELVKpnp 258
Cdd:TIGR04523 417 LQQEKELLEKEIERLKETIIKNNSEIKD-LTNQDSVKELI------IKNLDNTRESLETQLKVlSRSINKIKQNLEQ--- 486

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 259 vvpspsnisVQKQLKgdqSKEDQPKVDPSEDQEhLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREG 338
Cdd:TIGR04523 487 ---------KQKELK---SKEKELKKLNEEKKE-LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE 553

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2778098833 339 ------EKESQEREQ---ALREEVEALTKKCQELEEAKRQETQERQD 376
Cdd:TIGR04523 554 lkkenlEKEIDEKNKeieELKQTQKSLKKKQEEKQELIDQKEKEKKD 600
Leu_zip pfam15294
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 ...
 181-334 1.56e-03

Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 (LZTFL1) and Leucine zipper protein 2 (LUZP2).


Pssm-ID: 464620 [Multi-domain]  Cd Length: 276  Bit Score: 40.84  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 181 SSALLNLtrSVQELTEENQSLKEDLdRMLSnsptvSKIKGYVDwSKPRLLRRIAELEKKVSSSESPKNSASELVKpnpvv 260
Cdd:pfam15294 127 GSALLHM--EIERLKEENEKLKERL-KTLE-----SQATQALD-EKSKLEKALKDLQKEQGAKKDVKSNLKEISD----- 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 261 pspsnisVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQL--LGKDLE-----------MKQMLQSKID 327
Cdd:pfam15294 193 -------LEEKMAALKSDLEKTLNASTALQKSLEEDLASTKHELLKVQEQLemAEKELEkkfqqtaayrnMKEMLTKKNE 265


                  ....*..
gi 2778098833 328 LEKELET 334
Cdd:pfam15294 266 QIKELRK 272
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
288-376 2.25e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAK 367
Cdd:COG4372    45 EELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKER 124


                  ....*....
gi 2778098833 368 RQETQERQD 376
Cdd:COG4372   125 QDLEQQRKQ 133
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
105-366 2.47e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 105 LKQRIFRLEQQCKEKDSTINKL-----QTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEatGKKPILEKKMG--VKRQ 177
Cdd:PRK03918  191 IEELIKEKEKELEEVLREINEIsselpELREELEKLEKEVKELEELKEEIEELEKELESLE--GSKRKLEEKIRelEERI 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 178 KKMSSALLNLTRSVQELTE------ENQSLKEDLDRMLSNSPTVSKIKGyvdwskpRLLRRIAELEKKVSSSESPKNSAS 251
Cdd:PRK03918  269 EELKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLS-------RLEEEINGIEERIKELEEKEERLE 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 252 ELVKpnpvvpspsnisvqkqlkgdQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEmkqmlqskiDLEKE 331
Cdd:PRK03918  342 ELKK--------------------KLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE---------KLEKE 392

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2778098833 332 LETAREGEKESQEREQALREEVEALTKKCQELEEA 366
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427
IQ smart00015
Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln ...
 451-471 2.49e-03

Calmodulin-binding motif; Short calmodulin-binding motif containing conserved Ile and Gln residues.


Pssm-ID: 197470 [Multi-domain]  Cd Length: 23  Bit Score: 35.76  E-value: 2.49e-03
                           10        20
                   ....*....|....*....|.
gi 2778098833  451 LDEAATVLQAAFRGHLARSKL 471
Cdd:smart00015   2 LTRAAIIIQAAWRGYLARKRY 22
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
297-468 3.32e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  297 VKTLREELSALQEQLlgkdlemKQMLQSKIDLEkELETAREgekESQEREQALREEVEALTKKCQELEEaKRQETQERQD 376
Cdd:COG4913    663 VASAEREIAELEAEL-------ERLDASSDDLA-ALEEQLE---ELEAELEELEEELDELKGEIGRLEK-ELEQAEEELD 730

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  377 SFIAMTHEAhpevhapspcsrhsepdsdnnadnnagEDGGSQPPALCSEERREAAI-----RTLQAQWKAHRcKKRKAAL 451
Cdd:COG4913    731 ELQDRLEAA---------------------------EDLARLELRALLEERFAAALgdaveRELRENLEERI-DALRARL 782

                          170
                   ....*....|....*..
gi 2778098833  452 DEAATVLQAAFRGHLAR 468
Cdd:COG4913    783 NRAEEELERAMRAFNRE 799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-377 3.42e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 3.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAK 367
Cdd:COG1196   274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353

                          90
                  ....*....|
gi 2778098833 368 RQETQERQDS 377
Cdd:COG1196   354 EEAEAELAEA 363
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
296-369 4.12e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.39  E-value: 4.12e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2778098833 296 TVKTLREELSALQEQLLgkdlemKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAKRQ 369
Cdd:COG3206   292 DVIALRAQIAALRAQLQ------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLERE 359
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
288-376 4.24e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 4.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAK 367
Cdd:COG4372    59 EELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQI 138


                  ....*....
gi 2778098833 368 RQETQERQD 376
Cdd:COG4372   139 AELQSEIAE 147
IQ pfam00612
IQ calmodulin-binding motif; Calmodulin-binding motif.
 453-471 4.75e-03

IQ calmodulin-binding motif; Calmodulin-binding motif.


Pssm-ID: 459869  Cd Length: 21  Bit Score: 34.99  E-value: 4.75e-03
                          10
                  ....*....|....*....
gi 2778098833 453 EAATVLQAAFRGHLARSKL 471
Cdd:pfam00612   2 KAAIKIQAAWRGYLARKRY 20
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 168-370 6.64e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 39.95  E-value: 6.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  168 LEKKMGVK-RQKKMSSALLNLTRSVQELTE------ENQSLKEDLDRMLSNSPTVSKIKGYVDWSKPRLLRRIAELEKKV 240
Cdd:pfam02463  175 LKKLIEETeNLAELIIDLEELKLQELKLKEqakkalEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  241 SSSESPKNSASELVKpnpvvpSPSNISVQKQLKGDQSKEDqpkvDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQ 320
Cdd:pfam02463  255 SSKQEIEKEEEKLAQ------VLKENKEEEKEKKLQEEEL----KLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2778098833  321 MLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAKRQE 370
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE 374
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 288-376 8.10e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 38.37  E-value: 8.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 288 EDQEHLQGTVKTLREELSALQEQLL-GKDLEMKQMLQSKID-LEKELETAREGEKESQEREQALREEVEALTKKCQELEE 365
Cdd:COG1579    59 KEIKRLELEIEEVEARIKKYEEQLGnVRNNKEYEALQKEIEsLKRRISDLEDEILELMERIEELEEELAELEAELAELEA 138

                          90
                  ....*....|.
gi 2778098833 366 AKRQETQERQD 376
Cdd:COG1579   139 ELEEKKAELDE 149
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
31-376 8.74e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.25  E-value: 8.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833  31 REKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDpgRGPDFVRTLAEKKPDTGWV---ITGLKQ 107
Cdd:PRK02224  272 REREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELED--RDEELRDRLEECRVAAQAHneeAESLRE 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 108 RIFRLEQQCKEKDSTINKLQTDmkttnLEEMRIAMETYYEEIHRLQTLLASSEAtgkkpilekkmgvkrqkkmssALLNL 187
Cdd:PRK02224  350 DADDLEERAEELREEAAELESE-----LEEAREAVEDRREEIEELEEEIEELRE---------------------RFGDA 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 188 TRSVQELTEENQSLKEDLDRmlsnsptvskikgyvdwskprLLRRIAELEKKVSSSESPKNSASELVKPNpvvpspsnis 267
Cdd:PRK02224  404 PVDLGNAEDFLEELREERDE---------------------LREREAELEATLRTARERVEEAEALLEAG---------- 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2778098833 268 vqKQLKGDQSKEDQPKVDPSEDQ----EHLQGTVKTLREELSALQEQL-LGKDL-----EMKQMLQSKIDLEKELETARE 337
Cdd:PRK02224  453 --KCPECGQPVEGSPHVETIEEDrervEELEAELEDLEEEVEEVEERLeRAEDLveaedRIERLEERREDLEELIAERRE 530

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 2778098833 338 GEKESQEREQALREEVEALTKKCQELEEAKRQETQERQD 376
Cdd:PRK02224  531 TIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEE 569
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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