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Conserved domains on  [gi|21361370|ref|NP_002853|]
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glycogen phosphorylase, brain form [Homo sapiens]

Protein Classification

glycogen/starch/alpha-glucan phosphorylase( domain architecture ID 10136827)

glycogen/starch/alpha-glucan phosphorylase uses phosphate to catalyze the cleavage of alpha 1,4-linkages between pairs of glucose residues at the end of glucose polymers or oligomers, releasing alpha-D-glucose 1-phosphate

CATH:  3.40.50.2000
CAZY:  GT35
EC:  2.4.1.1
PubMed:  11340058|11949930
SCOP:  4000830

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GT35_Glycogen_Phosphorylase cd04300
glycogen phosphorylase and similar proteins; This is a family of oligosaccharide ...
29-828 0e+00

glycogen phosphorylase and similar proteins; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


:

Pssm-ID: 340853 [Multi-domain]  Cd Length: 795  Bit Score: 1484.32  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  29 RKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNA 108
Cdd:cd04300   1 KKSFVRHLEYTLGKDREEATPQDLYQALAYSVRDRLIERWNETQQYYYEKDPKRVYYLSLEFLMGRLLGNNLLNLGLYDE 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 109 CDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGN 188
Cdd:cd04300  81 VREALAELGLDLEDLEEEEPDAALGNGGLGRLAACFLDSMATLGLPAWGYGIRYEYGLFKQKIVDGYQVELPDYWLRYGN 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 189 PWEKARPEYMLPVHFYGRVEHTPDG----VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYI 264
Cdd:cd04300 161 PWEIRRPEVSVPVRFGGRVEEVPDGgrlrVRWVDGETVLAVPYDTPIPGYGTNTVNTLRLWSAKASDEFDLEAFNEGDYI 240
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 265 EAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDpvrtcfetFPDKVAIQLNDTHPA 344
Cdd:cd04300 241 RAVEQKNRAENISRVLYPNDSTYEGKELRLKQQYFFVSASLQDIIRRFKKSHGPLSE--------FPDKVAIQLNDTHPA 312
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 345 LSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVD 424
Cdd:cd04300 313 LAIPELMRILVDEEGLSWDEAWDITTKTFAYTNHTVLPEALEKWPVELFEKLLPRHLQIIYEINRRFLDEVRAKYPGDVD 392
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 425 RLRRMSVIEEGdcKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTI 504
Cdd:cd04300 393 RIRRMSIIEEG--KQVRMAHLAIVGSHSVNGVAALHTEILKTTVLKDFYELYPEKFNNKTNGITPRRWLLQANPGLAALI 470
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 505 VEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHV 584
Cdd:cd04300 471 TETIGDDWVTDLDQLKKLEPFADDPEFLEEWAAIKQANKARLAAYIKETTGVEVNPNSIFDVQVKRIHEYKRQLLNILHI 550
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 585 VTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLS 664
Cdd:cd04300 551 IYLYLRIKEGPPADFVPRTVIFGGKAAPGYYLAKLIIKLINAVADVVNNDPDVGDKLKVVFLPNYNVSLAEKIIPAADLS 630
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 665 QQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVD 744
Cdd:cd04300 631 EQISTAGKEASGTGNMKFMLNGALTIGTLDGANVEIAEEVGEENIFIFGLTAEEVEALRKNGYYPADYYENDPRLKRVLD 710
                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 745 QISSGFFSPKEPDCFKDIVNMLM-HHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:cd04300 711 QIISGTFSPGDPDEFRPLVDSLLnGNDEYLVLADFESYVDAQEKVDALYRDQEEWARKSILNIARSGKFSSDRTIREYAK 790

                ....*
gi 21361370 824 EIWGV 828
Cdd:cd04300 791 DIWNV 795
 
Name Accession Description Interval E-value
GT35_Glycogen_Phosphorylase cd04300
glycogen phosphorylase and similar proteins; This is a family of oligosaccharide ...
29-828 0e+00

glycogen phosphorylase and similar proteins; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340853 [Multi-domain]  Cd Length: 795  Bit Score: 1484.32  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  29 RKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNA 108
Cdd:cd04300   1 KKSFVRHLEYTLGKDREEATPQDLYQALAYSVRDRLIERWNETQQYYYEKDPKRVYYLSLEFLMGRLLGNNLLNLGLYDE 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 109 CDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGN 188
Cdd:cd04300  81 VREALAELGLDLEDLEEEEPDAALGNGGLGRLAACFLDSMATLGLPAWGYGIRYEYGLFKQKIVDGYQVELPDYWLRYGN 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 189 PWEKARPEYMLPVHFYGRVEHTPDG----VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYI 264
Cdd:cd04300 161 PWEIRRPEVSVPVRFGGRVEEVPDGgrlrVRWVDGETVLAVPYDTPIPGYGTNTVNTLRLWSAKASDEFDLEAFNEGDYI 240
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 265 EAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDpvrtcfetFPDKVAIQLNDTHPA 344
Cdd:cd04300 241 RAVEQKNRAENISRVLYPNDSTYEGKELRLKQQYFFVSASLQDIIRRFKKSHGPLSE--------FPDKVAIQLNDTHPA 312
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 345 LSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVD 424
Cdd:cd04300 313 LAIPELMRILVDEEGLSWDEAWDITTKTFAYTNHTVLPEALEKWPVELFEKLLPRHLQIIYEINRRFLDEVRAKYPGDVD 392
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 425 RLRRMSVIEEGdcKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTI 504
Cdd:cd04300 393 RIRRMSIIEEG--KQVRMAHLAIVGSHSVNGVAALHTEILKTTVLKDFYELYPEKFNNKTNGITPRRWLLQANPGLAALI 470
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 505 VEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHV 584
Cdd:cd04300 471 TETIGDDWVTDLDQLKKLEPFADDPEFLEEWAAIKQANKARLAAYIKETTGVEVNPNSIFDVQVKRIHEYKRQLLNILHI 550
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 585 VTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLS 664
Cdd:cd04300 551 IYLYLRIKEGPPADFVPRTVIFGGKAAPGYYLAKLIIKLINAVADVVNNDPDVGDKLKVVFLPNYNVSLAEKIIPAADLS 630
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 665 QQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVD 744
Cdd:cd04300 631 EQISTAGKEASGTGNMKFMLNGALTIGTLDGANVEIAEEVGEENIFIFGLTAEEVEALRKNGYYPADYYENDPRLKRVLD 710
                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 745 QISSGFFSPKEPDCFKDIVNMLM-HHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:cd04300 711 QIISGTFSPGDPDEFRPLVDSLLnGNDEYLVLADFESYVDAQEKVDALYRDQEEWARKSILNIARSGKFSSDRTIREYAK 790

                ....*
gi 21361370 824 EIWGV 828
Cdd:cd04300 791 DIWNV 795
Phosphorylase pfam00343
Carbohydrate phosphorylase; The members of this family catalyze the formation of glucose ...
141-828 0e+00

Carbohydrate phosphorylase; The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin.


Pssm-ID: 459770  Cd Length: 713  Bit Score: 1402.46  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   141 AACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG----VKW 216
Cdd:pfam00343  29 AACFLDSLATLGLPAYGYGIRYEYGLFKQKIVDGWQVELPDNWLRFGNPWEIRRPEVAVEVKFGGRVEEYTDGgrlrVRW 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   217 LDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQ 296
Cdd:pfam00343 109 VPGETVLAVPYDTPIPGYGTNTVNTLRLWSAEASEEFDLDAFNAGDYIRAVEEKNRAENISKVLYPNDSTEEGKELRLKQ 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   297 EYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYT 376
Cdd:pfam00343 189 QYFFVSASLQDIIRRFKK--------GGGDLDELPDKVAIQLNDTHPALAIPELMRILVDEEGLGWDEAWDITTKTFAYT 260
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   377 NHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGV 456
Cdd:pfam00343 261 NHTLLPEALEKWPVDLFERLLPRHLEIIYEINRRFLEEVRAKFPGDEDRLRRMSIIEEGGDKQVRMAHLAIVGSHSVNGV 340
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   457 ARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVA 536
Cdd:pfam00343 341 AALHTELLKETVFKDFYELYPEKFNNKTNGITPRRWLLLANPELAALITETIGDGWITDLDQLKKLEPFADDPAFLERWR 420
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   537 KVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHM 616
Cdd:pfam00343 421 AIKQANKQRLAAYIKKTTGIEVDPDSIFDVQVKRIHEYKRQLLNALHIITLYNRIKENPNADIVPRTFIFGGKAAPGYYM 500
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   617 AKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGA 696
Cdd:pfam00343 501 AKLIIKLINSVAEVVNNDPDVNDKLKVVFLPNYNVSLAEKIIPAADLSEQISTAGKEASGTGNMKFMLNGALTIGTLDGA 580
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   697 NVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLM-HHDRFKVF 775
Cdd:pfam00343 581 NVEIREEVGEENIFIFGLTAEEVEALRAKGYNPRDYYESNPELKRVLDQIASGTFSPGDPGLFRPLVDSLLnGGDPYLVL 660
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 21361370   776 ADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGV 828
Cdd:pfam00343 661 ADFESYVDAQERVDAAYRDREEWTRMSILNIARSGKFSSDRTIREYAEDIWKV 713
P_ylase TIGR02093
glycogen/starch/alpha-glucan phosphorylases; This family consists of phosphorylases. Members ...
32-828 0e+00

glycogen/starch/alpha-glucan phosphorylases; This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources. [Energy metabolism, Biosynthesis and degradation of polysaccharides]


Pssm-ID: 273967  Cd Length: 794  Bit Score: 1386.99  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370    32 FNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDE 111
Cdd:TIGR02093   1 ILYHLEYTYGKTIDDATPRDLYTALAKAVRDRLVDRWLETQEKYRDNNQKQVYYLSAEFLMGRLLGNNLLNLGLYDEVKE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   112 AIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWE 191
Cdd:TIGR02093  81 ALRELGLDLEEILEIENDAGLGNGGLGRLAACFLDSLATLGLPATGYGIRYEYGLFKQKIVDGWQVELPDDWLRYGNPWE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   192 KARPEYMLPVHFYGRVEHTPDG----VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAV 267
Cdd:TIGR02093 161 IRRPDRSYEVRFGGRVELQPDSdrlrPRWVPAETVLAIPYDVPVPGYRTDTVNTLRLWSAEAPEEFDLDAFNAGDYYEAV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   268 LDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPALSI 347
Cdd:TIGR02093 241 EEKNRAENISRVLYPNDSTYEGKELRLKQQYFFVSASLQDIIRRHLE--------THPDLSDFPKKVAIQLNDTHPALAI 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   348 PELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLR 427
Cdd:TIGR02093 313 PELMRLLIDEEGMDWDEAWDITTKTFAYTNHTLLPEALEKWPVDLFQKLLPRHLEIIYEINRRFLAELAAKGPGDEAKIR 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   428 RMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEK 507
Cdd:TIGR02093 393 RMSIIEEGQSKRVRMANLAIVGSHSVNGVAALHTELLKEDLLKDFYELYPEKFNNKTNGITPRRWLRLANPGLSALLTET 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   508 IGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTL 587
Cdd:TIGR02093 473 IGDDWLTDLDLLKKLEPYADDSEFLEEFRQVKQANKQRLAAYIKEHTGVEVDPNSIFDVQVKRLHEYKRQLLNVLHVIYL 552
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   588 YNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQI 667
Cdd:TIGR02093 553 YNRIKEDPPKDIVPRTVIFGGKAAPGYHMAKLIIKLINSVAEVVNNDPAVGDKLKVVFVPNYNVSLAELIIPAADLSEQI 632
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   668 STAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQIS 747
Cdd:TIGR02093 633 STAGKEASGTGNMKFMLNGALTIGTLDGANVEIREEVGAENIFIFGLTVEEVEALREKGYNPREYYEADPELKRVLDLIS 712
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   748 SGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIW 826
Cdd:TIGR02093 713 SGTFSPGDPGLFRPLYDSLLNHgDPFFVLADFAAYVDAQERVDALYRDQLEWTKKSILNIANSGKFSSDRTIREYAKEIW 792

                  ..
gi 21361370   827 GV 828
Cdd:TIGR02093 793 HV 794
GlgP COG0058
Glucan phosphorylase [Carbohydrate transport and metabolism];
24-828 0e+00

Glucan phosphorylase [Carbohydrate transport and metabolism];


Pssm-ID: 439828 [Multi-domain]  Cd Length: 795  Bit Score: 1256.97  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  24 DVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNL 103
Cdd:COG0058   4 NAEELFRAIDPELWETLGKRLEEAAADDWFLALAAAVRDYLSPRWFQTNRAYPDQKAKRVAYFSAEFLLGRSLGNNLLNL 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 104 GLQNACDEAIYQLGLDLEELEEIEEDAglgngglgrlAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDW 183
Cdd:COG0058  84 GLYDEVREALAELGLDLEDLLEQEPDLplgngglgrlAADFLKSASDLGLPAVGYGLRYEYGYFRQRIDDGWQVERPDNW 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 184 LRYGNPWEKARPEYMLPVHFYGrvehtPDGvkwlDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDY 263
Cdd:COG0058 164 LRYGDPWELPRPEPAVEVKFGD-----EDG----RTEDVLAVPYDVPIPGYRNNTVNTLRLWKAEASEEVGLYLFDAGDY 234
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 264 IEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKfgcrdpvrTCFETFPDKVAIQLNDTHP 343
Cdd:COG0058 235 TDAVENKPEDRNITKVLYPGDSEEAGKELRLRQEYFLGSGGVRDLRRLHLKTG--------GDLDGLPEPVVIHLNDTHP 306
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 344 ALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALfPGDV 423
Cdd:COG0058 307 AFAILELMRLLVDEHGLSWDEAWEITRATFVFTNHTPVPEALERWPVDLFERLLPRHLEIIGEINRRFLEEVRAR-PGDR 385
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 424 DRLRRMSVIEEGdckRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADT 503
Cdd:COG0058 386 ERLLRLGIIDEG---QFRMAHLALRGSHSVNGVSALHGEVLRETMFADFYPLWPVPFTNVTNGVHPRRWLLLANPELAEL 462
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 504 IVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLH 583
Cdd:COG0058 463 ITEYIGDGWITDLELLEKLEPIADDPAFQEELWEVKQANKERLAAYIRERTGIVLDPDALFDGFAKRFHEYKRQLLNLLH 542
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 584 VVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADL 663
Cdd:COG0058 543 DIERYNRILNNPNLDERPRQFIFAGKAAPGDEMGKLIIKLINAVARVPNNDPRVEFRLKVVFLENYDVSLAEKLVPGADV 622
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 664 SQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALdRKGYNAREYYDHLPELKQAV 743
Cdd:COG0058 623 WEQIPTAGKEASGTSGMKFALNGALTLGTLDGANVEIYEEVGDENGFAFGLTAEEVEAL-RAKYNPRDYYEADPELRRVL 701
                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 744 DQISSGFFSPkEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:COG0058 702 DQLASGYFSP-DPEEFRALYDLLLGGDPYLVLADFASYVDAEEEVDPLYRRPERWVRMMILNIARLGKFSSDRMIREYAE 780

                ....*
gi 21361370 824 EIWGV 828
Cdd:COG0058 781 RIWKL 785
PRK14986 PRK14986
glycogen phosphorylase; Provisional
25-833 0e+00

glycogen phosphorylase; Provisional


Pssm-ID: 184948 [Multi-domain]  Cd Length: 815  Bit Score: 941.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   25 VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLG 104
Cdd:PRK14986  14 VEALKHSIAYKLMFTIGKDPVIANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNALLSLG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  105 LQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWL 184
Cdd:PRK14986  94 IYDDVQGALEAMGLDLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGRQKESPDYWL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  185 RYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYI 264
Cdd:PRK14986 174 EYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILAVAYDQIIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYF 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  265 EAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPA 344
Cdd:PRK14986 254 AAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQDILSRHYQ--------LHKTYDNLADKIAIHLNDTHPV 325
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  345 LSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVD 424
Cdd:PRK14986 326 LSIPELMRLLIDEHKFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTD 405
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  425 RLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTI 504
Cdd:PRK14986 406 LLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFCNVTNGVTPRRWLALANPSLSAVL 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  505 VEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHV 584
Cdd:PRK14986 486 DEHIGRTWRTDLSQLSELKQHCDYPMVNHAVRQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHV 565
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  585 VTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLS 664
Cdd:PRK14986 566 ITRYNRIKADPDAKWVPRVNIFAGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLS 645
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  665 QQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVD 744
Cdd:PRK14986 646 EQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLEHVGEENIFIFGNTAEEVEALRRQGYKPREYYEKDEELHQVLT 725
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  745 QISSGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:PRK14986 726 QIGSGVFSPEEPGRYRDLVDSLINFgDHYQVLADYRSYVDCQDKVDELYRNQEEWTRKAMLNIANMGYFSSDRTIKEYAD 805
                        810
                 ....*....|
gi 21361370  824 EIWGVEPSDL 833
Cdd:PRK14986 806 EIWHIDPVRL 815
 
Name Accession Description Interval E-value
GT35_Glycogen_Phosphorylase cd04300
glycogen phosphorylase and similar proteins; This is a family of oligosaccharide ...
29-828 0e+00

glycogen phosphorylase and similar proteins; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340853 [Multi-domain]  Cd Length: 795  Bit Score: 1484.32  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  29 RKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNA 108
Cdd:cd04300   1 KKSFVRHLEYTLGKDREEATPQDLYQALAYSVRDRLIERWNETQQYYYEKDPKRVYYLSLEFLMGRLLGNNLLNLGLYDE 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 109 CDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGN 188
Cdd:cd04300  81 VREALAELGLDLEDLEEEEPDAALGNGGLGRLAACFLDSMATLGLPAWGYGIRYEYGLFKQKIVDGYQVELPDYWLRYGN 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 189 PWEKARPEYMLPVHFYGRVEHTPDG----VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYI 264
Cdd:cd04300 161 PWEIRRPEVSVPVRFGGRVEEVPDGgrlrVRWVDGETVLAVPYDTPIPGYGTNTVNTLRLWSAKASDEFDLEAFNEGDYI 240
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 265 EAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDpvrtcfetFPDKVAIQLNDTHPA 344
Cdd:cd04300 241 RAVEQKNRAENISRVLYPNDSTYEGKELRLKQQYFFVSASLQDIIRRFKKSHGPLSE--------FPDKVAIQLNDTHPA 312
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 345 LSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVD 424
Cdd:cd04300 313 LAIPELMRILVDEEGLSWDEAWDITTKTFAYTNHTVLPEALEKWPVELFEKLLPRHLQIIYEINRRFLDEVRAKYPGDVD 392
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 425 RLRRMSVIEEGdcKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTI 504
Cdd:cd04300 393 RIRRMSIIEEG--KQVRMAHLAIVGSHSVNGVAALHTEILKTTVLKDFYELYPEKFNNKTNGITPRRWLLQANPGLAALI 470
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 505 VEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHV 584
Cdd:cd04300 471 TETIGDDWVTDLDQLKKLEPFADDPEFLEEWAAIKQANKARLAAYIKETTGVEVNPNSIFDVQVKRIHEYKRQLLNILHI 550
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 585 VTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLS 664
Cdd:cd04300 551 IYLYLRIKEGPPADFVPRTVIFGGKAAPGYYLAKLIIKLINAVADVVNNDPDVGDKLKVVFLPNYNVSLAEKIIPAADLS 630
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 665 QQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVD 744
Cdd:cd04300 631 EQISTAGKEASGTGNMKFMLNGALTIGTLDGANVEIAEEVGEENIFIFGLTAEEVEALRKNGYYPADYYENDPRLKRVLD 710
                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 745 QISSGFFSPKEPDCFKDIVNMLM-HHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:cd04300 711 QIISGTFSPGDPDEFRPLVDSLLnGNDEYLVLADFESYVDAQEKVDALYRDQEEWARKSILNIARSGKFSSDRTIREYAK 790

                ....*
gi 21361370 824 EIWGV 828
Cdd:cd04300 791 DIWNV 795
Phosphorylase pfam00343
Carbohydrate phosphorylase; The members of this family catalyze the formation of glucose ...
141-828 0e+00

Carbohydrate phosphorylase; The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin.


Pssm-ID: 459770  Cd Length: 713  Bit Score: 1402.46  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   141 AACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG----VKW 216
Cdd:pfam00343  29 AACFLDSLATLGLPAYGYGIRYEYGLFKQKIVDGWQVELPDNWLRFGNPWEIRRPEVAVEVKFGGRVEEYTDGgrlrVRW 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   217 LDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQ 296
Cdd:pfam00343 109 VPGETVLAVPYDTPIPGYGTNTVNTLRLWSAEASEEFDLDAFNAGDYIRAVEEKNRAENISKVLYPNDSTEEGKELRLKQ 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   297 EYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYT 376
Cdd:pfam00343 189 QYFFVSASLQDIIRRFKK--------GGGDLDELPDKVAIQLNDTHPALAIPELMRILVDEEGLGWDEAWDITTKTFAYT 260
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   377 NHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGV 456
Cdd:pfam00343 261 NHTLLPEALEKWPVDLFERLLPRHLEIIYEINRRFLEEVRAKFPGDEDRLRRMSIIEEGGDKQVRMAHLAIVGSHSVNGV 340
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   457 ARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVA 536
Cdd:pfam00343 341 AALHTELLKETVFKDFYELYPEKFNNKTNGITPRRWLLLANPELAALITETIGDGWITDLDQLKKLEPFADDPAFLERWR 420
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   537 KVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHM 616
Cdd:pfam00343 421 AIKQANKQRLAAYIKKTTGIEVDPDSIFDVQVKRIHEYKRQLLNALHIITLYNRIKENPNADIVPRTFIFGGKAAPGYYM 500
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   617 AKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGA 696
Cdd:pfam00343 501 AKLIIKLINSVAEVVNNDPDVNDKLKVVFLPNYNVSLAEKIIPAADLSEQISTAGKEASGTGNMKFMLNGALTIGTLDGA 580
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   697 NVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLM-HHDRFKVF 775
Cdd:pfam00343 581 NVEIREEVGEENIFIFGLTAEEVEALRAKGYNPRDYYESNPELKRVLDQIASGTFSPGDPGLFRPLVDSLLnGGDPYLVL 660
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 21361370   776 ADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGV 828
Cdd:pfam00343 661 ADFESYVDAQERVDAAYRDREEWTRMSILNIARSGKFSSDRTIREYAEDIWKV 713
P_ylase TIGR02093
glycogen/starch/alpha-glucan phosphorylases; This family consists of phosphorylases. Members ...
32-828 0e+00

glycogen/starch/alpha-glucan phosphorylases; This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources. [Energy metabolism, Biosynthesis and degradation of polysaccharides]


Pssm-ID: 273967  Cd Length: 794  Bit Score: 1386.99  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370    32 FNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDE 111
Cdd:TIGR02093   1 ILYHLEYTYGKTIDDATPRDLYTALAKAVRDRLVDRWLETQEKYRDNNQKQVYYLSAEFLMGRLLGNNLLNLGLYDEVKE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   112 AIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWE 191
Cdd:TIGR02093  81 ALRELGLDLEEILEIENDAGLGNGGLGRLAACFLDSLATLGLPATGYGIRYEYGLFKQKIVDGWQVELPDDWLRYGNPWE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   192 KARPEYMLPVHFYGRVEHTPDG----VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAV 267
Cdd:TIGR02093 161 IRRPDRSYEVRFGGRVELQPDSdrlrPRWVPAETVLAIPYDVPVPGYRTDTVNTLRLWSAEAPEEFDLDAFNAGDYYEAV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   268 LDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPALSI 347
Cdd:TIGR02093 241 EEKNRAENISRVLYPNDSTYEGKELRLKQQYFFVSASLQDIIRRHLE--------THPDLSDFPKKVAIQLNDTHPALAI 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   348 PELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLR 427
Cdd:TIGR02093 313 PELMRLLIDEEGMDWDEAWDITTKTFAYTNHTLLPEALEKWPVDLFQKLLPRHLEIIYEINRRFLAELAAKGPGDEAKIR 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   428 RMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEK 507
Cdd:TIGR02093 393 RMSIIEEGQSKRVRMANLAIVGSHSVNGVAALHTELLKEDLLKDFYELYPEKFNNKTNGITPRRWLRLANPGLSALLTET 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   508 IGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTL 587
Cdd:TIGR02093 473 IGDDWLTDLDLLKKLEPYADDSEFLEEFRQVKQANKQRLAAYIKEHTGVEVDPNSIFDVQVKRLHEYKRQLLNVLHVIYL 552
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   588 YNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQI 667
Cdd:TIGR02093 553 YNRIKEDPPKDIVPRTVIFGGKAAPGYHMAKLIIKLINSVAEVVNNDPAVGDKLKVVFVPNYNVSLAELIIPAADLSEQI 632
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   668 STAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQIS 747
Cdd:TIGR02093 633 STAGKEASGTGNMKFMLNGALTIGTLDGANVEIREEVGAENIFIFGLTVEEVEALREKGYNPREYYEADPELKRVLDLIS 712
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   748 SGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIW 826
Cdd:TIGR02093 713 SGTFSPGDPGLFRPLYDSLLNHgDPFFVLADFAAYVDAQERVDALYRDQLEWTKKSILNIANSGKFSSDRTIREYAKEIW 792

                  ..
gi 21361370   827 GV 828
Cdd:TIGR02093 793 HV 794
GlgP COG0058
Glucan phosphorylase [Carbohydrate transport and metabolism];
24-828 0e+00

Glucan phosphorylase [Carbohydrate transport and metabolism];


Pssm-ID: 439828 [Multi-domain]  Cd Length: 795  Bit Score: 1256.97  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  24 DVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNL 103
Cdd:COG0058   4 NAEELFRAIDPELWETLGKRLEEAAADDWFLALAAAVRDYLSPRWFQTNRAYPDQKAKRVAYFSAEFLLGRSLGNNLLNL 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 104 GLQNACDEAIYQLGLDLEELEEIEEDAglgngglgrlAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDW 183
Cdd:COG0058  84 GLYDEVREALAELGLDLEDLLEQEPDLplgngglgrlAADFLKSASDLGLPAVGYGLRYEYGYFRQRIDDGWQVERPDNW 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 184 LRYGNPWEKARPEYMLPVHFYGrvehtPDGvkwlDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDY 263
Cdd:COG0058 164 LRYGDPWELPRPEPAVEVKFGD-----EDG----RTEDVLAVPYDVPIPGYRNNTVNTLRLWKAEASEEVGLYLFDAGDY 234
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 264 IEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKfgcrdpvrTCFETFPDKVAIQLNDTHP 343
Cdd:COG0058 235 TDAVENKPEDRNITKVLYPGDSEEAGKELRLRQEYFLGSGGVRDLRRLHLKTG--------GDLDGLPEPVVIHLNDTHP 306
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 344 ALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALfPGDV 423
Cdd:COG0058 307 AFAILELMRLLVDEHGLSWDEAWEITRATFVFTNHTPVPEALERWPVDLFERLLPRHLEIIGEINRRFLEEVRAR-PGDR 385
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 424 DRLRRMSVIEEGdckRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADT 503
Cdd:COG0058 386 ERLLRLGIIDEG---QFRMAHLALRGSHSVNGVSALHGEVLRETMFADFYPLWPVPFTNVTNGVHPRRWLLLANPELAEL 462
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 504 IVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLH 583
Cdd:COG0058 463 ITEYIGDGWITDLELLEKLEPIADDPAFQEELWEVKQANKERLAAYIRERTGIVLDPDALFDGFAKRFHEYKRQLLNLLH 542
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 584 VVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADL 663
Cdd:COG0058 543 DIERYNRILNNPNLDERPRQFIFAGKAAPGDEMGKLIIKLINAVARVPNNDPRVEFRLKVVFLENYDVSLAEKLVPGADV 622
                       650       660       670       680       690       700       710       720
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 664 SQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALdRKGYNAREYYDHLPELKQAV 743
Cdd:COG0058 623 WEQIPTAGKEASGTSGMKFALNGALTLGTLDGANVEIYEEVGDENGFAFGLTAEEVEAL-RAKYNPRDYYEADPELRRVL 701
                       730       740       750       760       770       780       790       800
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 744 DQISSGFFSPkEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:COG0058 702 DQLASGYFSP-DPEEFRALYDLLLGGDPYLVLADFASYVDAEEEVDPLYRRPERWVRMMILNIARLGKFSSDRMIREYAE 780

                ....*
gi 21361370 824 EIWGV 828
Cdd:COG0058 781 RIWKL 785
PRK14986 PRK14986
glycogen phosphorylase; Provisional
25-833 0e+00

glycogen phosphorylase; Provisional


Pssm-ID: 184948 [Multi-domain]  Cd Length: 815  Bit Score: 941.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   25 VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLG 104
Cdd:PRK14986  14 VEALKHSIAYKLMFTIGKDPVIANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNALLSLG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  105 LQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWL 184
Cdd:PRK14986  94 IYDDVQGALEAMGLDLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGRQKESPDYWL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  185 RYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYI 264
Cdd:PRK14986 174 EYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILAVAYDQIIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYF 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  265 EAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSskfgcrdpVRTCFETFPDKVAIQLNDTHPA 344
Cdd:PRK14986 254 AAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQDILSRHYQ--------LHKTYDNLADKIAIHLNDTHPV 325
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  345 LSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVD 424
Cdd:PRK14986 326 LSIPELMRLLIDEHKFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTD 405
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  425 RLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTI 504
Cdd:PRK14986 406 LLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFCNVTNGVTPRRWLALANPSLSAVL 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  505 VEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHV 584
Cdd:PRK14986 486 DEHIGRTWRTDLSQLSELKQHCDYPMVNHAVRQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHV 565
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  585 VTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLS 664
Cdd:PRK14986 566 ITRYNRIKADPDAKWVPRVNIFAGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLS 645
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  665 QQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVD 744
Cdd:PRK14986 646 EQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLEHVGEENIFIFGNTAEEVEALRRQGYKPREYYEKDEELHQVLT 725
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  745 QISSGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAR 823
Cdd:PRK14986 726 QIGSGVFSPEEPGRYRDLVDSLINFgDHYQVLADYRSYVDCQDKVDELYRNQEEWTRKAMLNIANMGYFSSDRTIKEYAD 805
                        810
                 ....*....|
gi 21361370  824 EIWGVEPSDL 833
Cdd:PRK14986 806 EIWHIDPVRL 815
PRK14985 PRK14985
maltodextrin phosphorylase; Provisional
85-826 0e+00

maltodextrin phosphorylase; Provisional


Pssm-ID: 237881 [Multi-domain]  Cd Length: 798  Bit Score: 818.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370   85 YLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEF 164
Cdd:PRK14985  63 YISMEFLIGRLTGNNLLNLGWYDDVQDVLKAYDINLTDLLEEETDPALGNGGLGRLAACFLDSMATVGQPATGYGLNYQY 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  165 GIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRL 244
Cdd:PRK14985 143 GLFRQSFVDGKQVEAPDDWHRDSYPWFRHNEALDVQVGIGGKVTKQDGRERWEPAFTITGEAWDLPVVGYRNGVAQPLRL 222
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  245 WSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKfgcrdpvR 324
Cdd:PRK14985 223 WQATHAHPFDLTKFNDGDFLRAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAG-------R 295
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  325 TcFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEII 404
Cdd:PRK14985 296 K-LHELPDYEVIQLNDTHPTIAIPELLRVLLDEHQLSWDDAWAITSKTFAYTNHTLMPEALECWDEKLVKSLLPRHMQII 374
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  405 YAINQRHLDHVAALFPGDVDRLRRMSVIEEgdcKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKT 484
Cdd:PRK14985 375 KEINTRFKTLVEKTWPGDKKVWAKLAVVHD---KQVRMANLCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVT 451
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  485 NGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMF 564
Cdd:PRK14985 452 NGITPRRWIKQCNPALAALLDKTLKKEWANDLDQLINLEKYADDAAFRQQYREIKQANKVRLAEFVKQRTGIEINPQAIF 531
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  565 DVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVI 644
Cdd:PRK14985 532 DVQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEVINNDPLVGDKLKVV 611
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  645 FLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDR 724
Cdd:PRK14985 612 FLPDYCVSAAELLIPAADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEQVGEENIFIFGHTVEQVKALLA 691
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370  725 KGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFkdivNMLMHH-----DRFKVFADYEAYMQCQAQVDQLYRNPKEWT 799
Cdd:PRK14985 692 KGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAF----DQMLHSlkqggDPYLVLADFAAYVEAQKQVDALYRDQEAWT 767
                        730       740
                 ....*....|....*....|....*..
gi 21361370  800 KKVIRNIACSGKFSSDRTITEYAREIW 826
Cdd:PRK14985 768 RAAILNTARCGMFSSDRSIRDYQARIW 794
GT35_Glycogen_Phosphorylase-like cd04299
proteins similar to glycogen phosphorylase; This family is most closely related to the ...
145-736 6.10e-23

proteins similar to glycogen phosphorylase; This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism.


Pssm-ID: 340852 [Multi-domain]  Cd Length: 776  Bit Score: 104.74  E-value: 6.10e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 145 LDSMATLGLAAYGYGIRYEFGIFNQKI-VNGWQVEEADdwlrYGNPwekarpeYMLPVhfygRVEHTPDGvkwldTQVVL 223
Cdd:cd04299 115 LKSASDLGVPLVGVGLLYRHGYFRQSLdSDGWQQELYP----ELDP-------GQLPL----EPVRDANG-----EPVRV 174
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 224 AMPYDtpvpgykNNTVNtMRLWSAkapndfklqdfNVGDYIEAVLDRNLAEN------ISRVLYPNDnffegKELRLKQE 297
Cdd:cd04299 175 TVELP-------DRRVH-ARVWRA-----------QVGRVPLYLLDTDVEENseddrkITDRLYGGD-----QELRIQQE 230
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 298 YFVVAATlqdiIRRFKSSKfgcrdpvrtcfetfPDKVAIQLNDTHPALSIPELMRILVDvEKVDWDKAWEITKKTCAYTN 377
Cdd:cd04299 231 ILLGIGG----IRALRALG--------------IKPDVFHLNEGHAAFLGLERIRELVA-EGLDFDEALELVRASTLFTT 291
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 378 HTVLPEALERWPVSMFEKLLPRHleiiyainqrhldhvaALFPG-DVDRLRRMSVIEEGDC-KRINMAHLCVIGSHAVNG 455
Cdd:cd04299 292 HTPVPAGIDRFPPDLVDRYLGGY----------------PELLGlSRDEFLALGREDPPDPgEPFNMAVLALRLSQRANG 355
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 456 VARIHSEiVKQSVFKDFY-ELEPEK--FQNKTNGITPRRWLllcNPGLADTIVEKIGEEFlTDLSQLKKLLPLVsDEVFI 532
Cdd:cd04299 356 VSKLHGE-VSREMFSNLWpGYPPEEvpIGHVTNGVHTPTWV---SPEMRELYDRYLGREW-RERPTLEDIWEAV-DQIPD 429
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 533 RDVAKVKQENKLKFSAFLEKEYKV-----------------KINPSSMFDVHVKRIHEYKRQLLNCLHVVTLyNRIKRDP 595
Cdd:cd04299 430 EELWEVRNTLRKRLVEFVRERLREqwlrngagpaeiaeldnALDPNVLTIGFARRFATYKRATLLLRDPERL-ARILNNP 508
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21361370 596 AKafvPRTVMIGGKAAPGYHMAKLIIKLVTSIGDvvnhDPVVGDRLkvIFLENYRVSLAEKVIPAADLSQQISTAGTEAS 675
Cdd:cd04299 509 ER---PVQFVFAGKAHPHDEGGKALIREIVRFSR----EPDFRGRI--IFLEDYDMQLARHLVQGVDVWLNNPRRPLEAS 579
                       570       580       590       600       610       620
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 21361370 676 GTGNMKFMLNGALTIGTMDGANVEMAEEagaENLFIFG-LRV-EDVEALDRKgyNAREYYDHL 736
Cdd:cd04299 580 GTSGMKAALNGGLNLSVLDGWWAEGYDG---KNGWAIGdERVyPDTEAQDAA--EAAALYDLL 637
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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