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Conserved domains on  [gi|154426302|ref|NP_059143|]
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protein EURL homolog isoform 2 [Homo sapiens]

Protein Classification

EURL domain-containing protein( domain architecture ID 10536525)

EURL domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
EURL pfam06937
EURL protein; This family consists of several animal EURL proteins. EURL is preferentially ...
1-290 0e+00

EURL protein; This family consists of several animal EURL proteins. EURL is preferentially expressed in chick retinal precursor cells as well as in the anterior epithelial cells of the lens at early stages of development. EURL transcripts are found primarily in the peripheral dorsal retina, i.e., the most undifferentiated part of the dorsal retina. EURL transcripts are also detected in the lens at stage 18 and remain abundant in the proliferating epithelial cells of the lens until at least day 11. The distribution pattern of EURL in the developing retina and lens suggest a role before the events leading to cell determination and differentiation.


:

Pssm-ID: 284377  Cd Length: 283  Bit Score: 517.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302    1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSK 80
Cdd:pfam06937   1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHVCFELNIEGIPKSDLLHTKSLRGHRDCFEKYHLIANQDCSRSKLSK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302   81 STYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQR 160
Cdd:pfam06937  81 STYEGVKTILSKKINWIIQYAQNKDLDSDSECSKTSQHPLLNFRHQPDRKLLPQFDSQVPRYSAKWIEGNAGSISNYGQS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302  161 ILEQRENTDFGLSMLQDSGAtlcrnsvLWPhSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQ 240
Cdd:pfam06937 161 MLEQHENTDFGLGMLQDTGA-------LWP-SHSRAQKTEKTDSGPETSPQRRHPHYSREELNSMTLGELKQLNEKLLQQ 232
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 154426302  241 IQ-VFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKS 290
Cdd:pfam06937 233 IQeVFEELTHQVQEKDSLASELHVRHIAIEQLLKNCSKLPCLQMGRAGVKS 283
 
Name Accession Description Interval E-value
EURL pfam06937
EURL protein; This family consists of several animal EURL proteins. EURL is preferentially ...
1-290 0e+00

EURL protein; This family consists of several animal EURL proteins. EURL is preferentially expressed in chick retinal precursor cells as well as in the anterior epithelial cells of the lens at early stages of development. EURL transcripts are found primarily in the peripheral dorsal retina, i.e., the most undifferentiated part of the dorsal retina. EURL transcripts are also detected in the lens at stage 18 and remain abundant in the proliferating epithelial cells of the lens until at least day 11. The distribution pattern of EURL in the developing retina and lens suggest a role before the events leading to cell determination and differentiation.


Pssm-ID: 284377  Cd Length: 283  Bit Score: 517.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302    1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSK 80
Cdd:pfam06937   1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHVCFELNIEGIPKSDLLHTKSLRGHRDCFEKYHLIANQDCSRSKLSK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302   81 STYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQR 160
Cdd:pfam06937  81 STYEGVKTILSKKINWIIQYAQNKDLDSDSECSKTSQHPLLNFRHQPDRKLLPQFDSQVPRYSAKWIEGNAGSISNYGQS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302  161 ILEQRENTDFGLSMLQDSGAtlcrnsvLWPhSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQ 240
Cdd:pfam06937 161 MLEQHENTDFGLGMLQDTGA-------LWP-SHSRAQKTEKTDSGPETSPQRRHPHYSREELNSMTLGELKQLNEKLLQQ 232
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 154426302  241 IQ-VFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKS 290
Cdd:pfam06937 233 IQeVFEELTHQVQEKDSLASELHVRHIAIEQLLKNCSKLPCLQMGRAGVKS 283
 
Name Accession Description Interval E-value
EURL pfam06937
EURL protein; This family consists of several animal EURL proteins. EURL is preferentially ...
1-290 0e+00

EURL protein; This family consists of several animal EURL proteins. EURL is preferentially expressed in chick retinal precursor cells as well as in the anterior epithelial cells of the lens at early stages of development. EURL transcripts are found primarily in the peripheral dorsal retina, i.e., the most undifferentiated part of the dorsal retina. EURL transcripts are also detected in the lens at stage 18 and remain abundant in the proliferating epithelial cells of the lens until at least day 11. The distribution pattern of EURL in the developing retina and lens suggest a role before the events leading to cell determination and differentiation.


Pssm-ID: 284377  Cd Length: 283  Bit Score: 517.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302    1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSK 80
Cdd:pfam06937   1 MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHVCFELNIEGIPKSDLLHTKSLRGHRDCFEKYHLIANQDCSRSKLSK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302   81 STYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQR 160
Cdd:pfam06937  81 STYEGVKTILSKKINWIIQYAQNKDLDSDSECSKTSQHPLLNFRHQPDRKLLPQFDSQVPRYSAKWIEGNAGSISNYGQS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154426302  161 ILEQRENTDFGLSMLQDSGAtlcrnsvLWPhSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQ 240
Cdd:pfam06937 161 MLEQHENTDFGLGMLQDTGA-------LWP-SHSRAQKTEKTDSGPETSPQRRHPHYSREELNSMTLGELKQLNEKLLQQ 232
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 154426302  241 IQ-VFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKS 290
Cdd:pfam06937 233 IQeVFEELTHQVQEKDSLASELHVRHIAIEQLLKNCSKLPCLQMGRAGVKS 283
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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