|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
5-311 |
5.88e-42 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 150.06 E-value: 5.88e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 5 LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETG 84
Cdd:COG2319 115 TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATG 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 85 KQLALLK-TNSAVRTCGFDFGGNIIMF-STDKQmgyqcfVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGECVI 162
Cdd:COG2319 195 KLLRTLTgHTGAVRSVAFSPDGKLLASgSADGT------VRLWDLATGKLLRT------LTGHSGSVRSVAFSPDGRLLA 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 163 AGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFR-TERPVNSAALSPNY 241
Cdd:COG2319 263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDG 342
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 242 DHVVLGGGQEAmdvtttstrigkfeARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:COG2319 343 KTLASGSDDGT--------------VRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
6-311 |
1.89e-35 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 129.76 E-value: 1.89e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 6 LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGK 85
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 86 QLALLKT-NSAVRTCgfdfggniiMFSTDKQM----GYQCFVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGEC 160
Cdd:cd00200 85 CVRTLTGhTSYVSSV---------AFSPDGRIlsssSRDKTIKVWDVETGKCLTT------LRGHTDWVNSVAFSPDGTF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 161 VIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSP 239
Cdd:cd00200 150 VASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSP 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9055370 240 NYDHVVLGggqeAMDVTTtstrigkfeaRFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:cd00200 230 DGYLLASG----SEDGTI----------RVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRI 287
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
42-80 |
3.05e-08 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 48.88 E-value: 3.05e-08
10 20 30
....*....|....*....|....*....|....*....
gi 9055370 42 GERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
41-80 |
3.58e-08 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 48.85 E-value: 3.58e-08
10 20 30 40
....*....|....*....|....*....|....*....|
gi 9055370 41 NGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
31-216 |
7.57e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 44.31 E-value: 7.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 31 DPIVNVWySVNGERLGTYMG-HTGAVWCVD-ADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGF--DFGGN 106
Cdd:PLN00181 554 EGVVQVW-DVARSQLVTEMKeHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFpsESGRS 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 107 IIMFSTDKQmgyqcfVSFFDLRDPsqidsnepymKIPCndskitsavwgplgeCVIAGhesgelnqysaksgevlvnvke 186
Cdd:PLN00181 633 LAFGSADHK------VYYYDLRNP----------KLPL---------------CTMIG---------------------- 659
|
170 180 190
....*....|....*....|....*....|
gi 9055370 187 HSRQINDIQLSrDMTMFVTASKDNTAKLFD 216
Cdd:PLN00181 660 HSKTVSYVRFV-DSSTLVSSSTDNTLKLWD 688
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
5-311 |
5.88e-42 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 150.06 E-value: 5.88e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 5 LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETG 84
Cdd:COG2319 115 TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATG 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 85 KQLALLK-TNSAVRTCGFDFGGNIIMF-STDKQmgyqcfVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGECVI 162
Cdd:COG2319 195 KLLRTLTgHTGAVRSVAFSPDGKLLASgSADGT------VRLWDLATGKLLRT------LTGHSGSVRSVAFSPDGRLLA 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 163 AGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFR-TERPVNSAALSPNY 241
Cdd:COG2319 263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDG 342
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 242 DHVVLGGGQEAmdvtttstrigkfeARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:COG2319 343 KTLASGSDDGT--------------VRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
6-311 |
8.73e-39 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 141.59 E-value: 8.73e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 6 LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGK 85
Cdd:COG2319 74 LLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGK 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 86 QLALLKTNSAVRTCgfdfggniIMFSTDKQM----GYQCFVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGECV 161
Cdd:COG2319 154 LLRTLTGHSGAVTS--------VAFSPDGKLlasgSDDGTVRLWDLATGKLLRT------LTGHTGAVRSVAFSPDGKLL 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 162 IAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSPN 240
Cdd:COG2319 220 ASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGhSGGVNSVAFSPD 299
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 9055370 241 YDHVVLGGGqeamDVTttstrigkfeARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:COG2319 300 GKLLASGSD----DGT----------VRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRL 356
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
5-311 |
1.69e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 132.73 E-value: 1.69e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 5 LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETG 84
Cdd:COG2319 31 LLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 85 KQLALLK-TNSAVRTCGFDFGGNIIMF-STDKQmgyqcfVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGECVI 162
Cdd:COG2319 111 LLLRTLTgHTGAVRSVAFSPDGKTLASgSADGT------VRLWDLATGKLLRT------LTGHSGAVTSVAFSPDGKLLA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 163 AGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSPNY 241
Cdd:COG2319 179 SGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDG 258
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 242 DHVVLGGGqeamDVTttstrigkfeARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:COG2319 259 RLLASGSA----DGT----------VRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
6-311 |
1.89e-35 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 129.76 E-value: 1.89e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 6 LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGK 85
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 86 QLALLKT-NSAVRTCgfdfggniiMFSTDKQM----GYQCFVSFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGEC 160
Cdd:cd00200 85 CVRTLTGhTSYVSSV---------AFSPDGRIlsssSRDKTIKVWDVETGKCLTT------LRGHTDWVNSVAFSPDGTF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 161 VIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSP 239
Cdd:cd00200 150 VASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSP 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9055370 240 NYDHVVLGggqeAMDVTTtstrigkfeaRFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:cd00200 230 DGYLLASG----SEDGTI----------RVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRI 287
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
45-311 |
2.53e-30 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 116.28 E-value: 2.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 45 LGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNS-AVRTCGF-DFGGNIIMFSTDKQmgyqcfV 122
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTgPVRDVAAsADGTYLASGSSDKT------I 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 123 SFFDLRDPSQIDSnepymkIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTM 202
Cdd:cd00200 76 RLWDLETGECVRT------LTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 203 FVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSPNYDHVVLGGGqeamDVTttstrigkfeARFFHLAFEEEFGRV 281
Cdd:cd00200 150 VASSSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSPDGEKLLSSSS----DGT----------IKLWDLSTGKCLGTL 215
|
250 260 270
....*....|....*....|....*....|
gi 9055370 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:cd00200 216 RGHENGVNSVAFSPDGYLLASGSEDGTIRV 245
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
6-219 |
9.96e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 105.76 E-value: 9.96e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 6 LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDadW--DTKHVLTGSADNSCRLWDCET 83
Cdd:COG2319 200 LTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVA--FspDGRLLASGSADGTVRLWDLAT 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 84 GKQLALLKT-NSAVRTCGFDFGGNIIMFSTDKQMgyqcfVSFFDLRDPSQIDSNEPYmkipcnDSKITSAVWGPLGECVI 162
Cdd:COG2319 278 GELLRTLTGhSGGVNSVAFSPDGKLLASGSDDGT-----VRLWDLATGKLLRTLTGH------TGAVRSVAFSPDGKTLA 346
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 9055370 163 AGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTT 219
Cdd:COG2319 347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
6-216 |
5.11e-24 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 99.33 E-value: 5.11e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 6 LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGK 85
Cdd:cd00200 47 LKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGK 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 86 QLALLKT-NSAVRTCGFDFGGNIIM-FSTDKQM-----------------------------GYQCFVS-------FFDL 127
Cdd:cd00200 127 CLTTLRGhTDWVNSVAFSPDGTFVAsSSQDGTIklwdlrtgkcvatltghtgevnsvafspdGEKLLSSssdgtikLWDL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 128 RDPSQIDSnepymkIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTAS 207
Cdd:cd00200 207 STGKCLGT------LRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGS 280
|
....*....
gi 9055370 208 KDNTAKLFD 216
Cdd:cd00200 281 ADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
5-80 |
1.19e-12 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 66.97 E-value: 1.19e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 9055370 5 LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
Cdd:cd00200 214 TLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
184-312 |
5.79e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 62.35 E-value: 5.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 184 VKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRT-ERPVNSAALSPNYDHVVLGGgqeaMDVTttstri 262
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGhTGPVRDVAASADGTYLASGS----SDKT------ 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 9055370 263 gkfeARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIH 312
Cdd:cd00200 75 ----IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVW 120
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
42-80 |
3.05e-08 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 48.88 E-value: 3.05e-08
10 20 30
....*....|....*....|....*....|....*....
gi 9055370 42 GERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
41-80 |
3.58e-08 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 48.85 E-value: 3.58e-08
10 20 30 40
....*....|....*....|....*....|....*....|
gi 9055370 41 NGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
282-311 |
1.60e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 41.18 E-value: 1.60e-05
10 20 30
....*....|....*....|....*....|
gi 9055370 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Cdd:pfam00400 8 EGHTGSVTSLAFSPDGKLLASGSDDGTVKV 37
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
282-312 |
3.08e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.37 E-value: 3.08e-05
10 20 30
....*....|....*....|....*....|.
gi 9055370 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVRIH 312
Cdd:smart00320 9 KGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
31-216 |
7.57e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 44.31 E-value: 7.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 31 DPIVNVWySVNGERLGTYMG-HTGAVWCVD-ADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGF--DFGGN 106
Cdd:PLN00181 554 EGVVQVW-DVARSQLVTEMKeHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFpsESGRS 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9055370 107 IIMFSTDKQmgyqcfVSFFDLRDPsqidsnepymKIPCndskitsavwgplgeCVIAGhesgelnqysaksgevlvnvke 186
Cdd:PLN00181 633 LAFGSADHK------VYYYDLRNP----------KLPL---------------CTMIG---------------------- 659
|
170 180 190
....*....|....*....|....*....|
gi 9055370 187 HSRQINDIQLSrDMTMFVTASKDNTAKLFD 216
Cdd:PLN00181 660 HSKTVSYVRFV-DSSTLVSSSTDNTLKLWD 688
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
177-216 |
2.05e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 38.06 E-value: 2.05e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 9055370 177 SGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFD 216
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
178-216 |
1.02e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.17 E-value: 1.02e-03
10 20 30
....*....|....*....|....*....|....*....
gi 9055370 178 GEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFD 216
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
|