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Conserved domains on  [gi|154350213|ref|NP_078817|]
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armadillo-like helical domain-containing protein 3 [Homo sapiens]

Protein Classification

ARMH3 family protein( domain architecture ID 10552642)

ARMH3 family protein is a DUF1741 domain-containing protein; similar to Homo sapiens armadillo-like helical domain-containing protein 3

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ARMH3_C pfam08427
Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain ...
441-669 2.98e-122

Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain of Armadillo-like helical domain- containing protein 3 (ARMH3), the previously uncharacterized peripheral Golgi protein C10orf76. ARMH3 interacts with and is involved in GBF1 recruitment, Golgi maintenance and protein secretion. The function of this domain is unknown.


:

Pssm-ID: 462473  Cd Length: 231  Bit Score: 363.42  E-value: 2.98e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  441 RPLVCAVLDLMVEFIVTHMMKEFPMDLYIRCIQVVHKLLCYQKKCRVRLHYTWRELWSALINLLKFLMSNETVLLAKHNI 520
Cdd:pfam08427   1 RPLAAAILDLMIDFINHNLRKRLDVDLYSLCLGIILRLLSYLKRSRVRLAYHWSELWRSLLSLLRFLTTYASDLKSLPNI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  521 FTLALMIVNLFNMFITYGDTFLPTPSSYDELYYEIIRMHQ---SFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAII 597
Cdd:pfam08427  81 FTLLDQVVNLFNLFISYGDTFLPDPASYDDLFYKLVEMGDvltKFRDLYGLALRYSTPASEYKESANRLTNSLDNLISIS 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 154350213  598 NHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQhKEAAFFKELVRSISTNVRR 669
Cdd:pfam08427 161 NHFKPLIESWSAKNKKKNLTPDQVLEVIKQGYDTLSLKLQEGLDQWEKYREA-DEKTFLKKMARVAVADARK 231
 
Name Accession Description Interval E-value
ARMH3_C pfam08427
Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain ...
441-669 2.98e-122

Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain of Armadillo-like helical domain- containing protein 3 (ARMH3), the previously uncharacterized peripheral Golgi protein C10orf76. ARMH3 interacts with and is involved in GBF1 recruitment, Golgi maintenance and protein secretion. The function of this domain is unknown.


Pssm-ID: 462473  Cd Length: 231  Bit Score: 363.42  E-value: 2.98e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  441 RPLVCAVLDLMVEFIVTHMMKEFPMDLYIRCIQVVHKLLCYQKKCRVRLHYTWRELWSALINLLKFLMSNETVLLAKHNI 520
Cdd:pfam08427   1 RPLAAAILDLMIDFINHNLRKRLDVDLYSLCLGIILRLLSYLKRSRVRLAYHWSELWRSLLSLLRFLTTYASDLKSLPNI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  521 FTLALMIVNLFNMFITYGDTFLPTPSSYDELYYEIIRMHQ---SFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAII 597
Cdd:pfam08427  81 FTLLDQVVNLFNLFISYGDTFLPDPASYDDLFYKLVEMGDvltKFRDLYGLALRYSTPASEYKESANRLTNSLDNLISIS 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 154350213  598 NHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQhKEAAFFKELVRSISTNVRR 669
Cdd:pfam08427 161 NHFKPLIESWSAKNKKKNLTPDQVLEVIKQGYDTLSLKLQEGLDQWEKYREA-DEKTFLKKMARVAVADARK 231
 
Name Accession Description Interval E-value
ARMH3_C pfam08427
Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain ...
441-669 2.98e-122

Armadillo-like helical domain-containing protein 3, C-terminal; This is the C-terminal domain of Armadillo-like helical domain- containing protein 3 (ARMH3), the previously uncharacterized peripheral Golgi protein C10orf76. ARMH3 interacts with and is involved in GBF1 recruitment, Golgi maintenance and protein secretion. The function of this domain is unknown.


Pssm-ID: 462473  Cd Length: 231  Bit Score: 363.42  E-value: 2.98e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  441 RPLVCAVLDLMVEFIVTHMMKEFPMDLYIRCIQVVHKLLCYQKKCRVRLHYTWRELWSALINLLKFLMSNETVLLAKHNI 520
Cdd:pfam08427   1 RPLAAAILDLMIDFINHNLRKRLDVDLYSLCLGIILRLLSYLKRSRVRLAYHWSELWRSLLSLLRFLTTYASDLKSLPNI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154350213  521 FTLALMIVNLFNMFITYGDTFLPTPSSYDELYYEIIRMHQ---SFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAII 597
Cdd:pfam08427  81 FTLLDQVVNLFNLFISYGDTFLPDPASYDDLFYKLVEMGDvltKFRDLYGLALRYSTPASEYKESANRLTNSLDNLISIS 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 154350213  598 NHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQhKEAAFFKELVRSISTNVRR 669
Cdd:pfam08427 161 NHFKPLIESWSAKNKKKNLTPDQVLEVIKQGYDTLSLKLQEGLDQWEKYREA-DEKTFLKKMARVAVADARK 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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