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AAA family ATPase Rvb1 [Schizosaccharomyces pombe]
RuvB-like helicase( domain architecture ID 15918217)
RuvB-like helicase is a DNA helicase that plays an essential role in various complexes involved in fundamental processes such as transcription regulation, DNA damage response and apoptosis (via the chromatin remodelling complexes SWR1, INO80 and TIP60), maturation of small nuclear ribonucleoproteins, cellular development, cancer metastasis, and regulation of mitosis
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||||
TIP49 | pfam06068 | TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ... |
15-369 | 0e+00 | ||||||
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. : Pssm-ID: 399217 [Multi-domain] Cd Length: 347 Bit Score: 621.64 E-value: 0e+00
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TIP49_C | pfam17856 | TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and ... |
375-440 | 2.37e-27 | ||||||
TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. : Pssm-ID: 436097 [Multi-domain] Cd Length: 66 Bit Score: 103.88 E-value: 2.37e-27
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Name | Accession | Description | Interval | E-value | |||||||
TIP49 | pfam06068 | TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ... |
15-369 | 0e+00 | |||||||
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. Pssm-ID: 399217 [Multi-domain] Cd Length: 347 Bit Score: 621.64 E-value: 0e+00
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TIP49 | COG1224 | DNA helicase TIP49, TBP-interacting protein [Transcription]; |
1-449 | 0e+00 | |||||||
DNA helicase TIP49, TBP-interacting protein [Transcription]; Pssm-ID: 440837 [Multi-domain] Cd Length: 452 Bit Score: 515.68 E-value: 0e+00
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TIP49_C | pfam17856 | TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and ... |
375-440 | 2.37e-27 | |||||||
TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. Pssm-ID: 436097 [Multi-domain] Cd Length: 66 Bit Score: 103.88 E-value: 2.37e-27
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RecA-like_protease | cd19481 | proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
64-120 | 1.25e-06 | |||||||
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.05 E-value: 1.25e-06
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ftsH | CHL00176 | cell division protein; Validated |
65-101 | 4.61e-05 | |||||||
cell division protein; Validated Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 45.81 E-value: 4.61e-05
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CDC48 | TIGR01243 | AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
65-120 | 1.47e-03 | |||||||
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus. Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 41.05 E-value: 1.47e-03
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AAA | smart00382 | ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
64-91 | 2.42e-03 | |||||||
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment. Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.51 E-value: 2.42e-03
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Name | Accession | Description | Interval | E-value | |||||||
TIP49 | pfam06068 | TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ... |
15-369 | 0e+00 | |||||||
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. Pssm-ID: 399217 [Multi-domain] Cd Length: 347 Bit Score: 621.64 E-value: 0e+00
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TIP49 | COG1224 | DNA helicase TIP49, TBP-interacting protein [Transcription]; |
1-449 | 0e+00 | |||||||
DNA helicase TIP49, TBP-interacting protein [Transcription]; Pssm-ID: 440837 [Multi-domain] Cd Length: 452 Bit Score: 515.68 E-value: 0e+00
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TIP49_C | pfam17856 | TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and ... |
375-440 | 2.37e-27 | |||||||
TIP49 AAA-lid domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases. Pssm-ID: 436097 [Multi-domain] Cd Length: 66 Bit Score: 103.88 E-value: 2.37e-27
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RecA-like_protease | cd19481 | proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
64-120 | 1.25e-06 | |||||||
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.05 E-value: 1.25e-06
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RPT1 | COG1222 | ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
44-120 | 2.34e-06 | |||||||
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 49.23 E-value: 2.34e-06
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RecA-like_FtsH | cd19501 | ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
42-101 | 3.02e-06 | |||||||
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 47.23 E-value: 3.02e-06
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AAA | cd00009 | The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
41-131 | 3.74e-06 | |||||||
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases. Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 46.76 E-value: 3.74e-06
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AAA | pfam00004 | ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
67-120 | 4.20e-06 | |||||||
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 46.05 E-value: 4.20e-06
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SpoVK | COG0464 | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
283-433 | 5.40e-06 | |||||||
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 48.37 E-value: 5.40e-06
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COG1223 | COG1223 | Predicted ATPase, AAA+ superfamily [General function prediction only]; |
41-140 | 6.67e-06 | |||||||
Predicted ATPase, AAA+ superfamily [General function prediction only]; Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 47.19 E-value: 6.67e-06
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SpoVK | COG0464 | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
64-120 | 8.17e-06 | |||||||
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 47.98 E-value: 8.17e-06
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RecA-like_CDC48_NLV2_r1-like | cd19503 | first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
65-120 | 9.00e-06 | |||||||
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 45.75 E-value: 9.00e-06
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RuvB_N | pfam05496 | Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
40-89 | 3.48e-05 | |||||||
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein. Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 44.03 E-value: 3.48e-05
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ftsH | CHL00176 | cell division protein; Validated |
65-101 | 4.61e-05 | |||||||
cell division protein; Validated Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 45.81 E-value: 4.61e-05
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hflB | PRK10733 | ATP-dependent zinc metalloprotease FtsH; |
42-101 | 1.05e-04 | |||||||
ATP-dependent zinc metalloprotease FtsH; Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 44.64 E-value: 1.05e-04
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ruvB | PRK00080 | Holliday junction branch migration DNA helicase RuvB; |
40-89 | 1.15e-04 | |||||||
Holliday junction branch migration DNA helicase RuvB; Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 43.97 E-value: 1.15e-04
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RecA-like_CDC48_r2-like | cd19511 | second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
65-120 | 1.74e-04 | |||||||
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 41.89 E-value: 1.74e-04
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PRK04195 | PRK04195 | replication factor C large subunit; Provisional |
41-89 | 1.74e-04 | |||||||
replication factor C large subunit; Provisional Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 43.76 E-value: 1.74e-04
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HolB | COG0470 | DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
43-89 | 2.15e-04 | |||||||
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 43.04 E-value: 2.15e-04
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PRK14957 | PRK14957 | DNA polymerase III subunits gamma and tau; Provisional |
299-411 | 2.87e-04 | |||||||
DNA polymerase III subunits gamma and tau; Provisional Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 43.15 E-value: 2.87e-04
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RecA-like_CDC48_r2-like | cd19528 | second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
58-112 | 5.96e-04 | |||||||
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 40.57 E-value: 5.96e-04
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HflB | COG0465 | ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; |
42-101 | 6.38e-04 | |||||||
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440233 [Multi-domain] Cd Length: 583 Bit Score: 41.95 E-value: 6.38e-04
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RecA-like_VCP_r2 | cd19529 | second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
65-120 | 7.43e-04 | |||||||
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 40.17 E-value: 7.43e-04
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PRK13342 | PRK13342 | recombination factor protein RarA; Reviewed |
40-89 | 8.76e-04 | |||||||
recombination factor protein RarA; Reviewed Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 41.61 E-value: 8.76e-04
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PRK14953 | PRK14953 | DNA polymerase III subunits gamma and tau; Provisional |
299-433 | 1.11e-03 | |||||||
DNA polymerase III subunits gamma and tau; Provisional Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 41.35 E-value: 1.11e-03
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CDC48 | TIGR01243 | AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
65-120 | 1.47e-03 | |||||||
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus. Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 41.05 E-value: 1.47e-03
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PRK03992 | PRK03992 | proteasome-activating nucleotidase; Provisional |
65-101 | 1.76e-03 | |||||||
proteasome-activating nucleotidase; Provisional Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 40.59 E-value: 1.76e-03
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RuvB | COG2255 | Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
40-89 | 2.29e-03 | |||||||
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair]; Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 40.06 E-value: 2.29e-03
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AAA | smart00382 | ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
64-91 | 2.42e-03 | |||||||
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment. Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.51 E-value: 2.42e-03
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rfc | PRK00440 | replication factor C small subunit; Reviewed |
68-88 | 2.53e-03 | |||||||
replication factor C small subunit; Reviewed Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 39.86 E-value: 2.53e-03
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RecA-like_NVL_r1-like | cd19518 | first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
65-123 | 2.62e-03 | |||||||
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion. Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 38.54 E-value: 2.62e-03
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dnaX_nterm | TIGR02397 | DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ... |
302-433 | 3.14e-03 | |||||||
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 274111 [Multi-domain] Cd Length: 355 Bit Score: 39.47 E-value: 3.14e-03
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PRK14962 | PRK14962 | DNA polymerase III subunits gamma and tau; Provisional |
299-433 | 3.98e-03 | |||||||
DNA polymerase III subunits gamma and tau; Provisional Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 39.36 E-value: 3.98e-03
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PRK08451 | PRK08451 | DNA polymerase III subunits gamma and tau; Validated |
302-411 | 5.29e-03 | |||||||
DNA polymerase III subunits gamma and tau; Validated Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 39.25 E-value: 5.29e-03
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PRK07133 | PRK07133 | DNA polymerase III subunits gamma and tau; Validated |
302-433 | 8.18e-03 | |||||||
DNA polymerase III subunits gamma and tau; Validated Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 38.65 E-value: 8.18e-03
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