NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|27262630|ref|NP_689511|]
View 

nuclear autoantigenic sperm protein isoform 3 [Homo sapiens]

Protein Classification

TPR_12 and SHNi-TPR domain-containing protein( domain architecture ID 12139966)

TPR_12 and SHNi-TPR domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 203-240 2.66e-09

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


:

Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 52.45  E-value: 2.66e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 27262630   203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
TPR_12 pfam13424
Tetratricopeptide repeat;
201-277 3.86e-07

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 3.86e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 27262630   201 YAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 138-340 2.18e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    138 TEGSEEDDKENDKTEEMPNDSVLENKSLqENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQlYAAQAHLKLGEVSVESE 217
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDL-ARLEAEVEQLEERIAQLSKELTELEAEIEELEE-RLEEAEEELAEAEAEIE 785

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGssaeyk 297
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA------ 859

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 27262630    298 kEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
Cdd:TIGR02168  860 -EIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901
 
Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 203-240 2.66e-09

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 52.45  E-value: 2.66e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 27262630   203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
TPR_12 pfam13424
Tetratricopeptide repeat;
201-277 3.86e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 3.86e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 27262630   201 YAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 203-273 3.78e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 3.78e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAhdrllaetHYQLGLAYGYNSQYDEAVAQFSKSIE 273
Cdd:COG3914 146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA--------LNNLGNALQDLGRLEEAIAAYRRALE 208
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
203-319 1.03e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 1.03e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRllaethyqLGLAYGYNSQYDEAVAQFSKSIEVIEN-RMAV 281
Cdd:COG4785 107 AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN--------RGIALYYLGRYELAIADLEKALELDPNdPERA 178

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 27262630 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319
Cdd:COG4785 179 LWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARE 216
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 138-340 2.18e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    138 TEGSEEDDKENDKTEEMPNDSVLENKSLqENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQlYAAQAHLKLGEVSVESE 217
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDL-ARLEAEVEQLEERIAQLSKELTELEAEIEELEE-RLEEAEEELAEAEAEIE 785

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGssaeyk 297
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA------ 859

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 27262630    298 kEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
Cdd:TIGR02168  860 -EIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 185-283 3.17e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.50  E-value: 3.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630  185 LAKIIFK----RQETKEAQLY-----AAQAHlklGEvsvesenYVQAVEEFQSCLNLQEqylEAHDRllAETHYQLGLAY 255
Cdd:PRK02603  18 MADLILKilpiNKKAKEAFVYyrdgmSAQAD---GE-------YAEALENYEEALKLEE---DPNDR--SYILYNMGIIY 82

                         90       100
                 ....*....|....*....|....*...
gi 27262630  256 GYNSQYDEAVAQFSKSIEVIENRMAVLN 283
Cdd:PRK02603  83 ASNGEHDKALEYYHQALELNPKQPSALN 110
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 245-277 6.30e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 6.30e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 27262630    245 AETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 203-240 2.66e-09

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 52.45  E-value: 2.66e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 27262630   203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
TPR_12 pfam13424
Tetratricopeptide repeat;
201-277 3.86e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 3.86e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 27262630   201 YAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 203-273 3.78e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 3.78e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAhdrllaetHYQLGLAYGYNSQYDEAVAQFSKSIE 273
Cdd:COG3914 146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA--------LNNLGNALQDLGRLEEAIAAYRRALE 208
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
203-319 1.03e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 1.03e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRllaethyqLGLAYGYNSQYDEAVAQFSKSIEVIEN-RMAV 281
Cdd:COG4785 107 AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN--------RGIALYYLGRYELAIADLEKALELDPNdPERA 178

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 27262630 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319
Cdd:COG4785 179 LWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARE 216
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
160-273 3.44e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.91  E-value: 3.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 160 LENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYlea 239
Cdd:COG4785  30 LFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDL--- 106

                        90       100       110
                ....*....|....*....|....*....|....
gi 27262630 240 hdrllAETHYQLGLAYGYNSQYDEAVAQFSKSIE 273
Cdd:COG4785 107 -----AEAYNNRGLAYLLLGDYDAALEDFDRALE 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 152-283 3.15e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.06  E-value: 3.15e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 152 EEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEA-QLYA---------AQAHLKLGEVSVESENYVQ 221
Cdd:COG3914  51 LAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEAlALYRralalnpdnAEALFNLGNLLLALGRLEE 130

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 27262630 222 AVEEFQSCLNLQEQYLEAHdrllaethYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLN 283
Cdd:COG3914 131 ALAALRRALALNPDFAEAY--------LNLGEALRRLGRLEEAIAALRRALELDPDNAEALN 184
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 174-307 3.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 3.56e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 174 GNLELAWDMLDLAKIIFkrQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHdRLLAETHYQLGl 253
Cdd:COG2956  49 GNLYRRRGEYDRAIRIH--QKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEAL-RLLAEIYEQEG- 124

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 27262630 254 aygynsQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSaEYKKEIEELKELL 307
Cdd:COG2956 125 ------DWEKAIEVLERLLKLGPENAHAYCELAELYLEQG-DYDEAIEALEKAL 171
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 177-309 3.59e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 3.59e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 177 ELAWDMLDLAKIIFKRQETKEAQLYA----------AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAhdrllae 246
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLekaleldpdnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEA------- 74

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 27262630 247 tHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNE--QVKEAEGSSAEYKKEIEELKELLPE 309
Cdd:COG4783  75 -RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRlaRAYRALGRPDEAIAALEKALELDPD 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
203-273 7.47e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 7.47e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYleahdrllAETHYQLGLAYGYNSQYDEAVAQFSKSIE 273
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDD--------AEALYNLGLAYLRLGRYEEALADYEQALE 70
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 162-307 1.70e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 1.70e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 162 NKSLQENEEEEIGNLELAWD-----MLDLAKIIFKRQETKEAqlYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQY 236
Cdd:COG2956  66 QKLLERDPDRAEALLELAQDylkagLLDRAEELLEKLLELDP--DDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 27262630 237 leahdrllAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNE--QVKEAEGssaEYKKEIEELKELL 307
Cdd:COG2956 144 --------AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLlaELYLEQG---DYEEAIAALERAL 205
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 138-340 2.18e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    138 TEGSEEDDKENDKTEEMPNDSVLENKSLqENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQlYAAQAHLKLGEVSVESE 217
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDL-ARLEAEVEQLEERIAQLSKELTELEAEIEELEE-RLEEAEEELAEAEAEIE 785

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGssaeyk 297
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA------ 859

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 27262630    298 kEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
Cdd:TIGR02168  860 -EIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 203-307 2.45e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 39.71  E-value: 2.45e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHdRLLAETHYQLGLaygynsqYDEAVAQFSKSIEVIENRMAVL 282
Cdd:COG2956  42 VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEAL-LELAQDYLKAGL-------LDRAEELLEKLLELDPDDAEAL 113

                        90       100
                ....*....|....*....|....*..
gi 27262630 283 NEQVK--EAEGssaEYKKEIEELKELL 307
Cdd:COG2956 114 RLLAEiyEQEG---DWEKAIEVLERLL 137
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 185-283 3.17e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.50  E-value: 3.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630  185 LAKIIFK----RQETKEAQLY-----AAQAHlklGEvsvesenYVQAVEEFQSCLNLQEqylEAHDRllAETHYQLGLAY 255
Cdd:PRK02603  18 MADLILKilpiNKKAKEAFVYyrdgmSAQAD---GE-------YAEALENYEEALKLEE---DPNDR--SYILYNMGIIY 82

                         90       100
                 ....*....|....*....|....*...
gi 27262630  256 GYNSQYDEAVAQFSKSIEVIENRMAVLN 283
Cdd:PRK02603  83 ASNGEHDKALEYYHQALELNPKQPSALN 110
TPR_1 pfam00515
Tetratricopeptide repeat;
245-277 4.08e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 4.08e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 27262630   245 AETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 143-335 4.22e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    143 EDDKENDKTEEMPNDSVLENKSLQ-ENEEEEIGNLElawDMLDLAKIifkRQETKEAQlyaaqahlKLGEVSVESENYVQ 221
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDlHKLEEALNDLE---ARLSHSRI---PEIQAELS--------KLEEEVSRIEARLR 815

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630    222 AVEEFQSCLNLQEQYLEAHDRLLAEthyqlglaygYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEY----- 296
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQE----------QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLesrlg 885

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 27262630    297 --KKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATL 335
Cdd:TIGR02169  886 dlKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
203-322 6.05e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.45  E-value: 6.05e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYleahdrllAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVL 282
Cdd:COG0457 110 AEALYNLGLALLELGRYDEAIEAYERALELDPDD--------ADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAA 181

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 27262630 283 NEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322
Cdd:COG0457 182 ALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAE 221
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 245-277 6.30e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 6.30e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 27262630    245 AETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 203-289 6.65e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.91  E-value: 6.65e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 203 AQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAhdrllaetHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN--RMA 280
Cdd:COG4235  51 ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA--------LYLLGLAAFQQGDYAEAIAAWQKLLALLPAdaPAR 122


                ....*....
gi 27262630 281 VLNEQVKEA 289
Cdd:COG4235 123 LLEASIAEA 131
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 201-270 9.43e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 35.74  E-value: 9.43e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27262630 201 YAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQyleahDRLLAETHYQLGLAYGYNSQYDEAVAQFSK 270
Cdd:COG1729  28 LAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPD-----SPKAPDALLKLGLSYLELGDYDKARATLEE 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH