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Conserved domains on  [gi|41872567|ref|NP_957719|]
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neuropilin-2 isoform 5 precursor [Homo sapiens]

Protein Classification

CUB domain-containing protein( domain architecture ID 11504395)

CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
280-426 7.88e-55

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


:

Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 186.40  E-value: 7.88e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 280 PLGMESGRiANEQISASSTYSDGrWTPQQSRLHGDdNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRetQNGYYVK 359
Cdd:cd00057   2 PLGMESGL-ADDQITASSSYSSG-WEASRARLNSD-NAWTPAVNDPPQWLQVDLGKTRRVTGIQTQGRKGG--GSSEWVT 76
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41872567 360 SYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFG 426
Cdd:cd00057  77 SYKVQYSLDGETWTTYKDKGEEKVFTGNSDGSTPVTNDFPPPIVARYIRILPTTWNGNISLRLELYG 143
MAM smart00137
Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an ...
641-794 1.25e-47

Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an adhesive function. Mutations in the meprin MAM domain affect noncovalent associations within meprin oligomers. In receptor tyrosine phosphatase mu-like molecules the MAM domain is important for homophilic cell-cell interactions.


:

Pssm-ID: 214533 [Multi-domain]  Cd Length: 161  Bit Score: 166.75  E-value: 1.25e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    641 PSGFNCNFDFlEEPCGWMYDHAKWLRTTWASS----SSPNDRTFPDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCM 716
Cdd:smart00137   1 TSPGNCDFEE-GSTCGWHQDSNDDGHWERVSSatgiPGPNRDHTTGNGHFMFFETSSGAEGQTARLLSPPLYENRSTHCL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    717 EFQYQATGGRGVALQV-VRE-ASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRISTD 794
Cdd:smart00137  80 TFWYYMYGSGSGTLNVyVREnNGSQDTLLWSRSGTQGGQWLQAEVALSSWPQPFQVVFEGTRGKGHSGYIALDDILLSNG 159
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
28-141 3.10e-41

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 146.79  E-value: 3.10e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567  28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFNpHFEIEKH-DCKYDFIEIRDGDSESADLLGKHCG 106
Cdd:cd00041   1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAP-PGYRIRLTFE-DFDLESSpNCSYDYLEIYDGPSTSSPLLGRFCG 78
                        90       100       110
                ....*....|....*....|....*....|....*
gi 41872567 107 NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Cdd:cd00041  79 STLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
149-265 6.50e-36

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 131.38  E-value: 6.50e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 149 CSKNFTSP-NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIG 227
Cdd:cd00041   1 CGGTLTAStSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSP------NCSYDYLEIYDGPSTSSPLLG 74
                        90       100       110
                ....*....|....*....|....*....|....*...
gi 41872567 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Cdd:cd00041  75 RFCGSTLPPPIISSGNSLTVRFRSDSSVTGRGFKATYS 112
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
438-591 8.95e-34

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


:

Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 126.70  E-value: 8.95e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 438 LGMLSGLiADSQISASSTQEYLWSPSAARLvSSRSGWFPRIPQAqpgEEWLQVDLGTPKTVKGVIIQGARGGDSItavea 517
Cdd:cd00057   3 LGMESGL-ADDQITASSSYSSGWEASRARL-NSDNAWTPAVNDP---PQWLQVDLGKTRRVTGIQTQGRKGGGSS----- 72
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41872567 518 rAFVRKFKVSYSLNGKDWEYIQDPRTqqPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPaGIGMRLEVLG 591
Cdd:cd00057  73 -EWVTSYKVQYSLDGETWTTYKDKGE--EKVFTGNSDGSTPVTNDFPpPIVARYIRILPTTWNG-NISLRLELYG 143
 
Name Accession Description Interval E-value
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
280-426 7.88e-55

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 186.40  E-value: 7.88e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 280 PLGMESGRiANEQISASSTYSDGrWTPQQSRLHGDdNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRetQNGYYVK 359
Cdd:cd00057   2 PLGMESGL-ADDQITASSSYSSG-WEASRARLNSD-NAWTPAVNDPPQWLQVDLGKTRRVTGIQTQGRKGG--GSSEWVT 76
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41872567 360 SYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFG 426
Cdd:cd00057  77 SYKVQYSLDGETWTTYKDKGEEKVFTGNSDGSTPVTNDFPPPIVARYIRILPTTWNGNISLRLELYG 143
MAM smart00137
Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an ...
641-794 1.25e-47

Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an adhesive function. Mutations in the meprin MAM domain affect noncovalent associations within meprin oligomers. In receptor tyrosine phosphatase mu-like molecules the MAM domain is important for homophilic cell-cell interactions.


Pssm-ID: 214533 [Multi-domain]  Cd Length: 161  Bit Score: 166.75  E-value: 1.25e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    641 PSGFNCNFDFlEEPCGWMYDHAKWLRTTWASS----SSPNDRTFPDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCM 716
Cdd:smart00137   1 TSPGNCDFEE-GSTCGWHQDSNDDGHWERVSSatgiPGPNRDHTTGNGHFMFFETSSGAEGQTARLLSPPLYENRSTHCL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    717 EFQYQATGGRGVALQV-VRE-ASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRISTD 794
Cdd:smart00137  80 TFWYYMYGSGSGTLNVyVREnNGSQDTLLWSRSGTQGGQWLQAEVALSSWPQPFQVVFEGTRGKGHSGYIALDDILLSNG 159
MAM pfam00629
MAM domain, meprin/A5/mu; An extracellular domain found in many receptors. The MAM domain ...
646-801 3.96e-43

MAM domain, meprin/A5/mu; An extracellular domain found in many receptors. The MAM domain along with the associated Ig domain in type IIB receptor protein tyrosine phosphatases forms a structural unit (termed MIg) with a seamless interdomain interface. It plays a major role in homodimerization of the phosphatase ectoprotein and in cell adhesion. MAM is a beta-sandwich consisting of two five-stranded antiparallel beta-sheets rotated away from each other by approx 25 degrees, and plays a similar role in meprin metalloproteinases.


Pssm-ID: 459878 [Multi-domain]  Cd Length: 159  Bit Score: 154.06  E-value: 3.96e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   646 CNFDFlEEPCGW---MYDHAKWLRTT--WASSSSPNDRTF-PDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQ 719
Cdd:pfam00629   1 CDFED-GNLCGWtqdSSDDFDWERVSgpSVKTGPSSDHTQgTGSGHFMYVDTSSGAPGQTARLLSPLLPPSRSPQCLRFW 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   720 YQATGGRGVALQV-VREASQES-KLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRIStdvpL 797
Cdd:pfam00629  80 YHMSGSGVGTLRVyVRENGGTLdTLLWSISGDQGPSWKEARVTLSSSTQPFQVVFEGIRGGGSRGGIALDDISLS----S 155

                  ....
gi 41872567   798 ENCM 801
Cdd:pfam00629 156 GPCP 159
MAM cd06263
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular ...
646-793 7.50e-43

Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members include: type IIB receptor protein tyrosine phosphatases (such as RPTPmu), meprins (plasma membrane metalloproteases), neuropilins (receptors of secreted semaphorins), and zonadhesins (sperm-specific membrane proteins which bind to the extracellular matrix of the egg). In meprin A and neuropilin-1 and -2, MAM is involved in homo-oligomerization. In RPTPmu, it has been associated with both homophilic adhesive (trans) interactions and lateral (cis) receptor oligomerization. In a GPI-anchored protein that is expressed in cells in the embryonic chicken spinal chord, MDGA1, the MAM domain has been linked to heterophilic interactions with axon-rich region.


Pssm-ID: 99706  Cd Length: 157  Bit Score: 152.92  E-value: 7.50e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 646 CNFDflEEPCGWM---YDHAKWLRTTWASSSS--PNDRTFPDDR-NFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQ 719
Cdd:cd06263   1 CDFE--DGLCGWTqdsTDDFDWTRVSGSTPSPgtPPDHTHGTGSgHYLYVESSSGREGQKARLLSPLLPPPRSSHCLSFW 78
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41872567 720 YQATGGRGVALQV-VRE-ASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRIST 793
Cdd:cd06263  79 YHMYGSGVGTLNVyVREeGGGLGTLLWSASGGQGNQWQEAEVTLSASSKPFQVVFEGVRGSGSRGDIALDDISLSP 154
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
28-141 3.10e-41

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 146.79  E-value: 3.10e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567  28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFNpHFEIEKH-DCKYDFIEIRDGDSESADLLGKHCG 106
Cdd:cd00041   1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAP-PGYRIRLTFE-DFDLESSpNCSYDYLEIYDGPSTSSPLLGRFCG 78
                        90       100       110
                ....*....|....*....|....*....|....*
gi 41872567 107 NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Cdd:cd00041  79 STLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
FA58C smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
277-427 4.13e-40

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 214572  Cd Length: 139  Bit Score: 144.57  E-value: 4.13e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    277 CNVPLGMESgriaNEQISASSTYsdgrWTPQQSRLHGD-DNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNG 355
Cdd:smart00231   2 CNEPLGLES----DSQITASSSY----WAAKIARLNGGsDGGWCPAKNDLPPWIQVDLGRLRTVTGVITGRRHGNGDWVT 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41872567    356 YYvksykLEVSTNGEDWMVYRHGkNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427
Cdd:smart00231  74 YK-----LEYSDDGVNWTTYKDG-NSKVFPGNSDAGTVVLNDFPPPIVARYVRILPTGWNGNIILRVELLGC 139
CUB pfam00431
CUB domain;
28-139 3.39e-37

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 135.12  E-value: 3.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    28 CGGRLNSKDaGYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFnPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCG 106
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAP-PGFRVKLTF-QDFELEDHDeCGYDYVEIRDGPSASSPLLGRFCG 77
                          90       100       110
                  ....*....|....*....|....*....|...
gi 41872567   107 NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Cdd:pfam00431  78 SGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
38-139 9.86e-37

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 133.67  E-value: 9.86e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567     38 GYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFNpHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISS 116
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAP-PGYRIELQFT-DFDLESSDnCEYDYVEIYDGPSASSPLLGRFCGSEAPPPVISS 78
                           90       100
                   ....*....|....*....|....
gi 41872567    117 -GSMLYIKFTSDYARQGAGFSLRY 139
Cdd:smart00042  79 sSNSLTLTFVSDSSVQKRGFSARY 102
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
149-265 6.50e-36

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 131.38  E-value: 6.50e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 149 CSKNFTSP-NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIG 227
Cdd:cd00041   1 CGGTLTAStSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSP------NCSYDYLEIYDGPSTSSPLLG 74
                        90       100       110
                ....*....|....*....|....*....|....*...
gi 41872567 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Cdd:cd00041  75 RFCGSTLPPPIISSGNSLTVRFRSDSSVTGRGFKATYS 112
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
438-591 8.95e-34

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 126.70  E-value: 8.95e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 438 LGMLSGLiADSQISASSTQEYLWSPSAARLvSSRSGWFPRIPQAqpgEEWLQVDLGTPKTVKGVIIQGARGGDSItavea 517
Cdd:cd00057   3 LGMESGL-ADDQITASSSYSSGWEASRARL-NSDNAWTPAVNDP---PQWLQVDLGKTRRVTGIQTQGRKGGGSS----- 72
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41872567 518 rAFVRKFKVSYSLNGKDWEYIQDPRTqqPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPaGIGMRLEVLG 591
Cdd:cd00057  73 -EWVTSYKVQYSLDGETWTTYKDKGE--EKVFTGNSDGSTPVTNDFPpPIVARYIRILPTTWNG-NISLRLELYG 143
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
158-264 2.62e-32

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 120.96  E-value: 2.62e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSE 237
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSD------NCEYDYVEIYDGPSASSPLLGRFCGSEAPPP 74
                           90       100
                   ....*....|....*....|....*...
gi 41872567    238 LRSSTG-ILSLTFHTDMAVAKDGFSARY 264
Cdd:smart00042  75 VISSSSnSLTLTFVSDSSVQKRGFSARY 102
CUB pfam00431
CUB domain;
149-264 9.95e-31

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 116.63  E-value: 9.95e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIGK 228
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHD------ECGYDYVEIRDGPSASSPLLGR 74
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 41872567   229 YCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Cdd:pfam00431  75 FCGSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
F5_F8_type_C pfam00754
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.
292-424 6.32e-29

F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.


Pssm-ID: 459925 [Multi-domain]  Cd Length: 127  Bit Score: 112.16  E-value: 6.32e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   292 QISASSTYSDGrwTPQQSRLHGDDN-GWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRetqNGYYVKSYKLEVSTNGE 370
Cdd:pfam00754   1 QITASSSYSGE--GPAAAALDGDPNtAWSAWSGDDPQWIQVDLGKPKKITGVVTQGRQDG---SNGYVTSYKIEYSLDGE 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 41872567   371 DWMVYRHGKnhkvFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSG--IALRLEL 424
Cdd:pfam00754  76 NWTTVKDEK----IPGNNDNNTPVTNTFDPPIKARYVRIVPTSWNGGngIALRAEL 127
F5_F8_type_C pfam00754
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.
449-589 5.86e-27

F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.


Pssm-ID: 459925 [Multi-domain]  Cd Length: 127  Bit Score: 106.38  E-value: 5.86e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   449 QISASSTQEYLWSPSAARLVSSRSGWfprIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGdsitaveARAFVRKFKVSY 528
Cdd:pfam00754   1 QITASSSYSGEGPAAAALDGDPNTAW---SAWSGDDPQWIQVDLGKPKKITGVVTQGRQDG-------SNGYVTSYKIEY 70
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41872567   529 SLNGKDWEYIQDPRTQqpklfeGNMHYDTPDIRRFD-PIPAQYVRVYPERW-SPAGIGMRLEV 589
Cdd:pfam00754  71 SLDGENWTTVKDEKIP------GNNDNNTPVTNTFDpPIKARYVRIVPTSWnGGNGIALRAEL 127
FA58C smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
433-592 6.08e-21

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 214572  Cd Length: 139  Bit Score: 89.88  E-value: 6.08e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    433 PCSNMLGMLSgliaDSQISASSTQeylWSPSAARL-VSSRSGWFPRIPQAQPgeeWLQVDLGTPKTVKGVIIQGARGGDS 511
Cdd:smart00231   1 PCNEPLGLES----DSQITASSSY---WAAKIARLnGGSDGGWCPAKNDLPP---WIQVDLGRLRTVTGVITGRRHGNGD 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    512 ITavearafvrKFKVSYSLNGKDWEYIQDprtQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWsPAGIGMRLEVL 590
Cdd:smart00231  71 WV---------TYKLEYSDDGVNWTTYKD---GNSKVFPGNSDAGTVVLNDFPpPIVARYVRILPTGW-NGNIILRVELL 137

                   ..
gi 41872567    591 GC 592
Cdd:smart00231 138 GC 139
 
Name Accession Description Interval E-value
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
280-426 7.88e-55

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 186.40  E-value: 7.88e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 280 PLGMESGRiANEQISASSTYSDGrWTPQQSRLHGDdNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRetQNGYYVK 359
Cdd:cd00057   2 PLGMESGL-ADDQITASSSYSSG-WEASRARLNSD-NAWTPAVNDPPQWLQVDLGKTRRVTGIQTQGRKGG--GSSEWVT 76
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41872567 360 SYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFG 426
Cdd:cd00057  77 SYKVQYSLDGETWTTYKDKGEEKVFTGNSDGSTPVTNDFPPPIVARYIRILPTTWNGNISLRLELYG 143
MAM smart00137
Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an ...
641-794 1.25e-47

Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others); Likely to have an adhesive function. Mutations in the meprin MAM domain affect noncovalent associations within meprin oligomers. In receptor tyrosine phosphatase mu-like molecules the MAM domain is important for homophilic cell-cell interactions.


Pssm-ID: 214533 [Multi-domain]  Cd Length: 161  Bit Score: 166.75  E-value: 1.25e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    641 PSGFNCNFDFlEEPCGWMYDHAKWLRTTWASS----SSPNDRTFPDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCM 716
Cdd:smart00137   1 TSPGNCDFEE-GSTCGWHQDSNDDGHWERVSSatgiPGPNRDHTTGNGHFMFFETSSGAEGQTARLLSPPLYENRSTHCL 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    717 EFQYQATGGRGVALQV-VRE-ASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRISTD 794
Cdd:smart00137  80 TFWYYMYGSGSGTLNVyVREnNGSQDTLLWSRSGTQGGQWLQAEVALSSWPQPFQVVFEGTRGKGHSGYIALDDILLSNG 159
MAM pfam00629
MAM domain, meprin/A5/mu; An extracellular domain found in many receptors. The MAM domain ...
646-801 3.96e-43

MAM domain, meprin/A5/mu; An extracellular domain found in many receptors. The MAM domain along with the associated Ig domain in type IIB receptor protein tyrosine phosphatases forms a structural unit (termed MIg) with a seamless interdomain interface. It plays a major role in homodimerization of the phosphatase ectoprotein and in cell adhesion. MAM is a beta-sandwich consisting of two five-stranded antiparallel beta-sheets rotated away from each other by approx 25 degrees, and plays a similar role in meprin metalloproteinases.


Pssm-ID: 459878 [Multi-domain]  Cd Length: 159  Bit Score: 154.06  E-value: 3.96e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   646 CNFDFlEEPCGW---MYDHAKWLRTT--WASSSSPNDRTF-PDDRNFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQ 719
Cdd:pfam00629   1 CDFED-GNLCGWtqdSSDDFDWERVSgpSVKTGPSSDHTQgTGSGHFMYVDTSSGAPGQTARLLSPLLPPSRSPQCLRFW 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   720 YQATGGRGVALQV-VREASQES-KLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRIStdvpL 797
Cdd:pfam00629  80 YHMSGSGVGTLRVyVRENGGTLdTLLWSISGDQGPSWKEARVTLSSSTQPFQVVFEGIRGGGSRGGIALDDISLS----S 155

                  ....
gi 41872567   798 ENCM 801
Cdd:pfam00629 156 GPCP 159
MAM cd06263
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular ...
646-793 7.50e-43

Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members include: type IIB receptor protein tyrosine phosphatases (such as RPTPmu), meprins (plasma membrane metalloproteases), neuropilins (receptors of secreted semaphorins), and zonadhesins (sperm-specific membrane proteins which bind to the extracellular matrix of the egg). In meprin A and neuropilin-1 and -2, MAM is involved in homo-oligomerization. In RPTPmu, it has been associated with both homophilic adhesive (trans) interactions and lateral (cis) receptor oligomerization. In a GPI-anchored protein that is expressed in cells in the embryonic chicken spinal chord, MDGA1, the MAM domain has been linked to heterophilic interactions with axon-rich region.


Pssm-ID: 99706  Cd Length: 157  Bit Score: 152.92  E-value: 7.50e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 646 CNFDflEEPCGWM---YDHAKWLRTTWASSSS--PNDRTFPDDR-NFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQ 719
Cdd:cd06263   1 CDFE--DGLCGWTqdsTDDFDWTRVSGSTPSPgtPPDHTHGTGSgHYLYVESSSGREGQKARLLSPLLPPPRSSHCLSFW 78
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41872567 720 YQATGGRGVALQV-VRE-ASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRIST 793
Cdd:cd06263  79 YHMYGSGVGTLNVyVREeGGGLGTLLWSASGGQGNQWQEAEVTLSASSKPFQVVFEGVRGSGSRGDIALDDISLSP 154
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
28-141 3.10e-41

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 146.79  E-value: 3.10e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567  28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFNpHFEIEKH-DCKYDFIEIRDGDSESADLLGKHCG 106
Cdd:cd00041   1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAP-PGYRIRLTFE-DFDLESSpNCSYDYLEIYDGPSTSSPLLGRFCG 78
                        90       100       110
                ....*....|....*....|....*....|....*
gi 41872567 107 NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
Cdd:cd00041  79 STLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
FA58C smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
277-427 4.13e-40

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 214572  Cd Length: 139  Bit Score: 144.57  E-value: 4.13e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    277 CNVPLGMESgriaNEQISASSTYsdgrWTPQQSRLHGD-DNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNG 355
Cdd:smart00231   2 CNEPLGLES----DSQITASSSY----WAAKIARLNGGsDGGWCPAKNDLPPWIQVDLGRLRTVTGVITGRRHGNGDWVT 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41872567    356 YYvksykLEVSTNGEDWMVYRHGkNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427
Cdd:smart00231  74 YK-----LEYSDDGVNWTTYKDG-NSKVFPGNSDAGTVVLNDFPPPIVARYVRILPTGWNGNIILRVELLGC 139
CUB pfam00431
CUB domain;
28-139 3.39e-37

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 135.12  E-value: 3.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    28 CGGRLNSKDaGYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFnPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCG 106
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAP-PGFRVKLTF-QDFELEDHDeCGYDYVEIRDGPSASSPLLGRFCG 77
                          90       100       110
                  ....*....|....*....|....*....|...
gi 41872567   107 NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Cdd:pfam00431  78 SGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
38-139 9.86e-37

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 133.67  E-value: 9.86e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567     38 GYITSPGYPQDYPSHQNCEWIVYAPePNQKIVLNFNpHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISS 116
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAP-PGYRIELQFT-DFDLESSDnCEYDYVEIYDGPSASSPLLGRFCGSEAPPPVISS 78
                           90       100
                   ....*....|....*....|....
gi 41872567    117 -GSMLYIKFTSDYARQGAGFSLRY 139
Cdd:smart00042  79 sSNSLTLTFVSDSSVQKRGFSARY 102
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
149-265 6.50e-36

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 131.38  E-value: 6.50e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 149 CSKNFTSP-NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIG 227
Cdd:cd00041   1 CGGTLTAStSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSP------NCSYDYLEIYDGPSTSSPLLG 74
                        90       100       110
                ....*....|....*....|....*....|....*...
gi 41872567 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Cdd:cd00041  75 RFCGSTLPPPIISSGNSLTVRFRSDSSVTGRGFKATYS 112
FA58C cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
438-591 8.95e-34

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 238014 [Multi-domain]  Cd Length: 143  Bit Score: 126.70  E-value: 8.95e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567 438 LGMLSGLiADSQISASSTQEYLWSPSAARLvSSRSGWFPRIPQAqpgEEWLQVDLGTPKTVKGVIIQGARGGDSItavea 517
Cdd:cd00057   3 LGMESGL-ADDQITASSSYSSGWEASRARL-NSDNAWTPAVNDP---PQWLQVDLGKTRRVTGIQTQGRKGGGSS----- 72
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41872567 518 rAFVRKFKVSYSLNGKDWEYIQDPRTqqPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPaGIGMRLEVLG 591
Cdd:cd00057  73 -EWVTSYKVQYSLDGETWTTYKDKGE--EKVFTGNSDGSTPVTNDFPpPIVARYIRILPTTWNG-NISLRLELYG 143
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
158-264 2.62e-32

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 120.96  E-value: 2.62e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSE 237
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSD------NCEYDYVEIYDGPSASSPLLGRFCGSEAPPP 74
                           90       100
                   ....*....|....*....|....*...
gi 41872567    238 LRSSTG-ILSLTFHTDMAVAKDGFSARY 264
Cdd:smart00042  75 VISSSSnSLTLTFVSDSSVQKRGFSARY 102
CUB pfam00431
CUB domain;
149-264 9.95e-31

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 116.63  E-value: 9.95e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPlqvgegDCKYDWLDIWDGIPHVGPLIGK 228
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHD------ECGYDYVEIRDGPSASSPLLGR 74
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 41872567   229 YCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Cdd:pfam00431  75 FCGSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
F5_F8_type_C pfam00754
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.
292-424 6.32e-29

F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.


Pssm-ID: 459925 [Multi-domain]  Cd Length: 127  Bit Score: 112.16  E-value: 6.32e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   292 QISASSTYSDGrwTPQQSRLHGDDN-GWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRetqNGYYVKSYKLEVSTNGE 370
Cdd:pfam00754   1 QITASSSYSGE--GPAAAALDGDPNtAWSAWSGDDPQWIQVDLGKPKKITGVVTQGRQDG---SNGYVTSYKIEYSLDGE 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 41872567   371 DWMVYRHGKnhkvFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSG--IALRLEL 424
Cdd:pfam00754  76 NWTTVKDEK----IPGNNDNNTPVTNTFDPPIKARYVRIVPTSWNGGngIALRAEL 127
F5_F8_type_C pfam00754
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.
449-589 5.86e-27

F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.


Pssm-ID: 459925 [Multi-domain]  Cd Length: 127  Bit Score: 106.38  E-value: 5.86e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567   449 QISASSTQEYLWSPSAARLVSSRSGWfprIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGdsitaveARAFVRKFKVSY 528
Cdd:pfam00754   1 QITASSSYSGEGPAAAALDGDPNTAW---SAWSGDDPQWIQVDLGKPKKITGVVTQGRQDG-------SNGYVTSYKIEY 70
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41872567   529 SLNGKDWEYIQDPRTQqpklfeGNMHYDTPDIRRFD-PIPAQYVRVYPERW-SPAGIGMRLEV 589
Cdd:pfam00754  71 SLDGENWTTVKDEKIP------GNNDNNTPVTNTFDpPIKARYVRIVPTSWnGGNGIALRAEL 127
FA58C smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ...
433-592 6.08e-21

Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.


Pssm-ID: 214572  Cd Length: 139  Bit Score: 89.88  E-value: 6.08e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    433 PCSNMLGMLSgliaDSQISASSTQeylWSPSAARL-VSSRSGWFPRIPQAQPgeeWLQVDLGTPKTVKGVIIQGARGGDS 511
Cdd:smart00231   1 PCNEPLGLES----DSQITASSSY---WAAKIARLnGGSDGGWCPAKNDLPP---WIQVDLGRLRTVTGVITGRRHGNGD 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41872567    512 ITavearafvrKFKVSYSLNGKDWEYIQDprtQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWsPAGIGMRLEVL 590
Cdd:smart00231  71 WV---------TYKLEYSDDGVNWTTYKD---GNSKVFPGNSDAGTVVLNDFPpPIVARYVRILPTGW-NGNIILRVELL 137

                   ..
gi 41872567    591 GC 592
Cdd:smart00231 138 GC 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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