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glutathione peroxidase 1 isoform 2 [Homo sapiens]
thioredoxin domain-containing protein( domain architecture ID 144)
thioredoxin domain-containing protein may function as a thiol disulfide oxidoreductase that catalyzes the oxidation or reduction of protein disulfide bonds using an active site dithiol, present in a CXXC motif
List of domain hits
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Name | Accession | Description | Interval | E-value | ||
Thioredoxin_like super family | cl00388 | Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; The thioredoxin ... |
16-84 | 6.31e-36 | ||
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; The thioredoxin (TRX)-like superfamily is a large, diverse group of proteins containing a TRX fold. Many members contain a classic TRX domain with a redox active CXXC motif. They function as protein disulfide oxidoreductases (PDOs), altering the redox state of target proteins via the reversible oxidation of their active site dithiol. The PDO members of this superfamily include the families of TRX, protein disulfide isomerase (PDI), tlpA, glutaredoxin, NrdH redoxin, and bacterial Dsb proteins (DsbA, DsbC, DsbG, DsbE, DsbDgamma). Members of the superfamily that do not function as PDOs but contain a TRX-fold domain include phosducins, peroxiredoxins, glutathione (GSH) peroxidases, SCO proteins, GSH transferases (GST, N-terminal domain), arsenic reductases, TRX-like ferredoxins and calsequestrin, among others. The actual alignment was detected with superfamily member pfam00255: Pssm-ID: 469754 Cd Length: 108 Bit Score: 117.84 E-value: 6.31e-36
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Name | Accession | Description | Interval | E-value | ||
GSHPx | pfam00255 | Glutathione peroxidase; |
16-84 | 6.31e-36 | ||
Glutathione peroxidase; Pssm-ID: 395197 Cd Length: 108 Bit Score: 117.84 E-value: 6.31e-36
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GSH_Peroxidase | cd00340 | Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a ... |
15-84 | 3.13e-34 | ||
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes. Pssm-ID: 238207 [Multi-domain] Cd Length: 152 Bit Score: 114.92 E-value: 3.13e-34
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BtuE | COG0386 | Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides [Defense mechanisms, Lipid ... |
15-84 | 4.62e-28 | ||
Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides [Defense mechanisms, Lipid transport and metabolism]; Pssm-ID: 440155 [Multi-domain] Cd Length: 161 Bit Score: 99.38 E-value: 4.62e-28
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gpx7 | TIGR02540 | putative glutathione peroxidase Gpx7; This model represents one of several families of known ... |
15-90 | 1.15e-18 | ||
putative glutathione peroxidase Gpx7; This model represents one of several families of known and probable glutathione peroxidases. This family is restricted to animals and designated GPX7. Pssm-ID: 131592 [Multi-domain] Cd Length: 153 Bit Score: 75.26 E-value: 1.15e-18
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PTZ00056 | PTZ00056 | glutathione peroxidase; Provisional |
15-84 | 6.12e-18 | ||
glutathione peroxidase; Provisional Pssm-ID: 240248 [Multi-domain] Cd Length: 199 Bit Score: 74.50 E-value: 6.12e-18
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Name | Accession | Description | Interval | E-value | ||
GSHPx | pfam00255 | Glutathione peroxidase; |
16-84 | 6.31e-36 | ||
Glutathione peroxidase; Pssm-ID: 395197 Cd Length: 108 Bit Score: 117.84 E-value: 6.31e-36
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GSH_Peroxidase | cd00340 | Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a ... |
15-84 | 3.13e-34 | ||
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes. Pssm-ID: 238207 [Multi-domain] Cd Length: 152 Bit Score: 114.92 E-value: 3.13e-34
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BtuE | COG0386 | Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides [Defense mechanisms, Lipid ... |
15-84 | 4.62e-28 | ||
Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides [Defense mechanisms, Lipid transport and metabolism]; Pssm-ID: 440155 [Multi-domain] Cd Length: 161 Bit Score: 99.38 E-value: 4.62e-28
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gpx7 | TIGR02540 | putative glutathione peroxidase Gpx7; This model represents one of several families of known ... |
15-90 | 1.15e-18 | ||
putative glutathione peroxidase Gpx7; This model represents one of several families of known and probable glutathione peroxidases. This family is restricted to animals and designated GPX7. Pssm-ID: 131592 [Multi-domain] Cd Length: 153 Bit Score: 75.26 E-value: 1.15e-18
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PTZ00056 | PTZ00056 | glutathione peroxidase; Provisional |
15-84 | 6.12e-18 | ||
glutathione peroxidase; Provisional Pssm-ID: 240248 [Multi-domain] Cd Length: 199 Bit Score: 74.50 E-value: 6.12e-18
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btuE | PRK10606 | putative glutathione peroxidase; Provisional |
27-84 | 2.81e-16 | ||
putative glutathione peroxidase; Provisional Pssm-ID: 182585 [Multi-domain] Cd Length: 183 Bit Score: 69.80 E-value: 2.81e-16
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PLN02412 | PLN02412 | probable glutathione peroxidase |
14-84 | 4.18e-16 | ||
probable glutathione peroxidase Pssm-ID: 166053 [Multi-domain] Cd Length: 167 Bit Score: 68.86 E-value: 4.18e-16
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PLN02399 | PLN02399 | phospholipid hydroperoxide glutathione peroxidase |
14-84 | 6.48e-16 | ||
phospholipid hydroperoxide glutathione peroxidase Pssm-ID: 178021 [Multi-domain] Cd Length: 236 Bit Score: 69.54 E-value: 6.48e-16
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PTZ00256 | PTZ00256 | glutathione peroxidase; Provisional |
15-84 | 4.67e-14 | ||
glutathione peroxidase; Provisional Pssm-ID: 173495 [Multi-domain] Cd Length: 183 Bit Score: 64.01 E-value: 4.67e-14
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Blast search parameters | ||||
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