|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
16-268 |
8.66e-103 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
:
Pssm-ID: 214532 Cd Length: 238 Bit Score: 329.71 E-value: 8.66e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 16 QCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVehvpGRPVRNPQCRICDGNsaNPRERHPISHAIDGTN----N 91
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCDAR--NPRRSHPAENLTDGNNpnnpT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 92 WWQSPSIQNGReyHWVTITLDLRQVFQVAYVIIKAAnAPRPGNWILERSLDGTTFSPWQYYAvsdSECLSRYNITPRRGP 171
Cdd:smart00136 75 WWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 172 PTYrADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLShrepkel 249
Cdd:smart00136 149 TKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELMDDR------- 220
|
250
....*....|....*....
gi 281185471 250 dPIVTRRYYYSIKDISVGG 268
Cdd:smart00136 221 -PEVTRRYYYAISDIAVGG 238
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
1575-1830 |
9.35e-100 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
:
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 322.05 E-value: 9.35e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1575 VLSLN-LTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK---LEGVAEETDNLQKKLTRMLASTQKVNRATERI 1650
Cdd:pfam06008 1 LLSLNsLTGALPAPYKINYNLENLTKQLQEYLSPENAHKIQIEILekeLSSLAQETEELQKKATQTLAKAQQVNAESERT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1651 FKESQDLAIAIERLQMSITEIMEKT-TLNQtldEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLL 1729
Cdd:pfam06008 81 LGHAKELAEAIKNLIDNIKEINEKVaTLGE---NDFALPSSDLSRMLAEAQRMLGEIRSRDFGTQLQNAEAELKAAQDLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1730 SQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSEL 1809
Cdd:pfam06008 158 SRIQTWFQSPQEENKALANALRDSLAEYEAKLSDLRELLREAAAKTRDANRLNLANQANLREFQRKKEEVSEQKNQLEET 237
|
250 260
....*....|....*....|.
gi 281185471 1810 IVQGRGLIDAAAAQTDAVQDA 1830
Cdd:pfam06008 238 LKTARDSLDAANLLLQEIDDA 258
|
|
| Laminin_II |
pfam06009 |
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 ... |
2011-2145 |
8.12e-57 |
|
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
:
Pssm-ID: 368703 [Multi-domain] Cd Length: 138 Bit Score: 193.86 E-value: 8.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2011 TKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKM 2090
Cdd:pfam06009 1 SKELAREANETAKEVLEQLAPLSQNLENTSEKLSGINRSLEETNELVNDANKALDDAGRSVKKLEELAPDLLDKLKPLKQ 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2091 LEEN---LSRNLSEIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLN 2145
Cdd:pfam06009 81 LEVNsssLSDNISRIKELIAQARKAANSIKVSVSFDGDSIVELRPPISVTDLAAYTSL 138
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
1218-1344 |
1.00e-50 |
|
Laminin B (Domain IV);
:
Pssm-ID: 459652 Cd Length: 136 Bit Score: 176.31 E-value: 1.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYf 1297
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 281185471 1298 nsVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Cdd:pfam00052 80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV 124
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2743-2872 |
4.30e-47 |
|
Laminin G domain;
:
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 165.95 E-value: 4.30e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2743 IRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVT 2822
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSVDGEARPTGE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 2823 VVGDGTM-LDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLD 2872
Cdd:pfam00054 81 SPLGATTdLDVDGPLYVGGLPSLGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| LamB |
smart00281 |
Laminin B domain; |
563-695 |
3.88e-45 |
|
Laminin B domain;
:
Pssm-ID: 214597 Cd Length: 127 Bit Score: 160.12 E-value: 3.88e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 563 LAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTLSTQAEGlSLQPYEEYLNVVRLVP 642
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFRE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 643 ENFQDFHsKRQIDRDQLMTVLANVTHLLIRANYnSAKMALYRLESVSLDIASS 695
Cdd:smart00281 77 ENWQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2307-2463 |
2.32e-39 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
:
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 144.48 E-value: 2.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2307 SFHFDGSGY-SVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNG 2385
Cdd:cd00110 1 GVSFSGSSYvRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLNDG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2386 TWYKIAFQRNRKQGVLaVIDAYntsnketKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEI 2463
Cdd:cd00110 81 QWHSVSVERNGRSVTL-SVDGE-------RVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKV 150
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2892-3043 |
1.03e-35 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
:
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 134.08 E-value: 1.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2892 GTYFDGSGYAALVKEGYKVQSDvNITLEFRTSSQNGVLLGISTA-KVDAIGLELVDGKVLFHVNNGAGRITAAYEpktaT 2970
Cdd:cd00110 1 GVSFSGSSYVRLPTLPAPRTRL-SISFSFRTTSPNGLLLYAGSQnGGDFLALELEDGRLVLRYDLGSGSLVLSSK----T 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2971 VLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:cd00110 76 PLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDL 148
|
|
| LamG |
smart00282 |
Laminin G domain; |
2141-2280 |
1.31e-31 |
|
Laminin G domain;
:
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 121.68 E-value: 1.31e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2141 TLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVkem 2220
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSV--- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2221 ssNQKSPTKTSkSPGTANVLDVNnsTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
Cdd:smart00282 78 --DGGNRVSGE-SPGGLTILNLD--GPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2514-2658 |
1.48e-29 |
|
Laminin G domain;
:
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 115.49 E-value: 1.48e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2514 FATTNSSGIILaaLGGDVEKRgdreeahvPFFSVMLIGGNIEVHVNPGDGtglrKALLHAPTgTCSDGQAHSISLVRNRR 2593
Cdd:pfam00054 1 FRTTEPSGLLL--YNGTQTER--------DFLALELRDGRLEVSYDLGSG----AAVVRSGD-KLNDGKWHSVELERNGR 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2594 IITVQLDENNPV--EMKLGTLVesrTINVSN-LYVGGIPE-GEGTSLLTMRRSFHGCIKNLIFNLELLD 2658
Cdd:pfam00054 66 SGTLSVDGEARPtgESPLGATT---DLDVDGpLYVGGLPSlGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
902-948 |
5.44e-15 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 71.23 E-value: 5.44e-15
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL--DSGHGC 948
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
454-500 |
3.72e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 3.72e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
Cdd:pfam00053 1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1044-1092 |
4.66e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 4.66e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 1044 CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDC 1092
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1090-1147 |
3.66e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 63.14 E-value: 3.66e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 1090 CDCDLRGTSGDACNLEqglcgcveeTGACPCKENVFGPQCNECREGTFALRADNPLGC 1147
Cdd:pfam00053 1 CDCNPHGSLSDTCDPE---------TGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1509-1546 |
1.17e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.17e-11
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
951-998 |
1.39e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.39e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 951 CNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
Cdd:pfam00053 1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
397-456 |
2.90e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.44 E-value: 2.90e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 397 CNCDPVGSLSSVCikdDLHSdlhngkqpGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGC 456
Cdd:pfam00053 1 CDCNPHGSLSDTC---DPET--------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
848-900 |
8.81e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 59.29 E-value: 8.81e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 848 PCDCSGNvdPSEAGHCDSVTGECLkCLGNTDGAHCERCADGFYGDAVTAKNCR 900
Cdd:cd00055 1 PCDCNGH--GSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1403-1449 |
1.74e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 58.52 E-value: 1.74e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 1403 CSCNNH---SDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYGKVTGSASDC 1449
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
998-1041 |
2.59e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.75 E-value: 2.59e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 998 CDCPH---TQNTCDPETGECVCPPHTQGVKCEECEDGHWGY--DAEVGC 1041
Cdd:pfam00053 1 CDCNPhgsLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
741-789 |
6.60e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.98 E-value: 6.60e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 741 PCECHGHAA---ECN-VHGVCIaCAHNTTGVHCEQCLPGFYGEPSRgtPGDCQ 789
Cdd:cd00055 1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
791-846 |
2.39e-08 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 52.36 E-value: 2.39e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 281185471 791 CACPLTIASnnfSPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNPTVPGESC 846
Cdd:pfam00053 1 CDCNPHGSL---SDTCDPETG---QCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
270-317 |
1.34e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.43 E-value: 1.34e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 270 CICYGHAS---SCpwDETTkkLQCQCEHNTCGESCNRCCPGYHQQPWRPGT 317
Cdd:cd00055 2 CDCNGHGSlsgQC--DPGT--GQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1452-1506 |
1.58e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 50.04 E-value: 1.58e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 1452 CACPHSppASFSPTCVLEGdhdFRCDaCLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
Cdd:pfam00053 1 CDCNPH--GSLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Tar super family |
cl43297 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
1763-2102 |
3.46e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
The actual alignment was detected with superfamily member COG0840:
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 46.17 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1763 AAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLL 1842
Cdd:COG0840 28 ALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1843 LWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARD 1922
Cdd:COG0840 108 ALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAA 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1923 AHRTVTETSLLSESLVSNGKAAVQRSSRFLKE--GNNLSRKLP-GIALELSELRNKTNRFQENAVEITRQTNESLLILRA 1999
Cdd:COG0840 188 LLALVALAIILALLLSRSITRPLRELLEVLERiaEGDLTVRIDvDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVAS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2000 IPKGIRdkgAKTKELATSASQSAvSTLRDVAGLSQELlntSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQAN 2079
Cdd:COG0840 268 ASEELA---ASAEELAAGAEEQA-ASLEETAAAMEEL---SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIE 340
|
330 340
....*....|....*....|....*..
gi 281185471 2080 LLFDRLKPL----KMLEENlSRNLSEI 2102
Cdd:COG0840 341 EIRESVEETaetiEELGES-SQEIGEI 366
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
16-268 |
8.66e-103 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
Pssm-ID: 214532 Cd Length: 238 Bit Score: 329.71 E-value: 8.66e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 16 QCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVehvpGRPVRNPQCRICDGNsaNPRERHPISHAIDGTN----N 91
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCDAR--NPRRSHPAENLTDGNNpnnpT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 92 WWQSPSIQNGReyHWVTITLDLRQVFQVAYVIIKAAnAPRPGNWILERSLDGTTFSPWQYYAvsdSECLSRYNITPRRGP 171
Cdd:smart00136 75 WWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 172 PTYrADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLShrepkel 249
Cdd:smart00136 149 TKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELMDDR------- 220
|
250
....*....|....*....
gi 281185471 250 dPIVTRRYYYSIKDISVGG 268
Cdd:smart00136 221 -PEVTRRYYYAISDIAVGG 238
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
1575-1830 |
9.35e-100 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 322.05 E-value: 9.35e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1575 VLSLN-LTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK---LEGVAEETDNLQKKLTRMLASTQKVNRATERI 1650
Cdd:pfam06008 1 LLSLNsLTGALPAPYKINYNLENLTKQLQEYLSPENAHKIQIEILekeLSSLAQETEELQKKATQTLAKAQQVNAESERT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1651 FKESQDLAIAIERLQMSITEIMEKT-TLNQtldEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLL 1729
Cdd:pfam06008 81 LGHAKELAEAIKNLIDNIKEINEKVaTLGE---NDFALPSSDLSRMLAEAQRMLGEIRSRDFGTQLQNAEAELKAAQDLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1730 SQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSEL 1809
Cdd:pfam06008 158 SRIQTWFQSPQEENKALANALRDSLAEYEAKLSDLRELLREAAAKTRDANRLNLANQANLREFQRKKEEVSEQKNQLEET 237
|
250 260
....*....|....*....|.
gi 281185471 1810 IVQGRGLIDAAAAQTDAVQDA 1830
Cdd:pfam06008 238 LKTARDSLDAANLLLQEIDDA 258
|
|
| Laminin_N |
pfam00055 |
Laminin N-terminal (Domain VI); |
22-268 |
1.26e-87 |
|
Laminin N-terminal (Domain VI);
Pssm-ID: 459653 Cd Length: 230 Bit Score: 286.02 E-value: 1.26e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 22 LFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGrpvrnPQCRICDgnSANPRERHPISHAIDGTNN----WWQSPS 97
Cdd:pfam00055 1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSGLEGG-----KKCFICD--SRDPHNSHPPSNLTDSNNGtnetWWQSET 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 98 IQngREYHWVTITLDLRQVFQVAYVIIKAAnAPRPGNWILERSLD-GTTFSPWQYYAvsdSECLSRYNITPRrgPPTYRA 176
Cdd:pfam00055 74 GV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRPSG--PSRGIK 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 177 DDEVICTSYYSRLVPLEHGEIHTSLINGRPSA--DDLSPKLLEFTSARYIRLRLQRIRTLNADLMTlshrepkelDPIVT 254
Cdd:pfam00055 146 DDEVICTSEYSDISPLTGGEVIFSTLEGRPSAniFDYSPELQDWLTATNIRIRLLRLHTLGDELLD---------DPSVL 216
|
250
....*....|....
gi 281185471 255 RRYYYSIKDISVGG 268
Cdd:pfam00055 217 RKYYYAISDISVGG 230
|
|
| Laminin_II |
pfam06009 |
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 ... |
2011-2145 |
8.12e-57 |
|
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 368703 [Multi-domain] Cd Length: 138 Bit Score: 193.86 E-value: 8.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2011 TKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKM 2090
Cdd:pfam06009 1 SKELAREANETAKEVLEQLAPLSQNLENTSEKLSGINRSLEETNELVNDANKALDDAGRSVKKLEELAPDLLDKLKPLKQ 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2091 LEEN---LSRNLSEIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLN 2145
Cdd:pfam06009 81 LEVNsssLSDNISRIKELIAQARKAANSIKVSVSFDGDSIVELRPPISVTDLAAYTSL 138
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
1218-1344 |
1.00e-50 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 176.31 E-value: 1.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYf 1297
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 281185471 1298 nsVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Cdd:pfam00052 80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV 124
|
|
| LamB |
smart00281 |
Laminin B domain; |
1213-1344 |
1.76e-49 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 172.45 E-value: 1.76e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1213 RAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGvGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEqeVAMREN 1292
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRG-GTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVE--VRFREE 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 281185471 1293 FWKYFNsvsEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Cdd:smart00281 78 NWQYYG---GRPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAV 126
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2743-2872 |
4.30e-47 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 165.95 E-value: 4.30e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2743 IRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVT 2822
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSVDGEARPTGE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 2823 VVGDGTM-LDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLD 2872
Cdd:pfam00054 81 SPLGATTdLDVDGPLYVGGLPSLGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| LamB |
smart00281 |
Laminin B domain; |
563-695 |
3.88e-45 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 160.12 E-value: 3.88e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 563 LAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTLSTQAEGlSLQPYEEYLNVVRLVP 642
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFRE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 643 ENFQDFHsKRQIDRDQLMTVLANVTHLLIRANYnSAKMALYRLESVSLDIASS 695
Cdd:smart00281 77 ENWQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
568-707 |
2.52e-43 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 155.12 E-value: 2.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 568 YWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETvdSNLMSHADVIIKGNGLTLST-QAEGLSLQPYEEYLNVVRLVPENFQ 646
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSEPDVILEGNGLRLSYsSPDQPPPDPGQEQTYSVRLHEENWR 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281185471 647 DfHSKRQIDRDQLMTVLANVTHLLIRANYNSaKMALYRLESVSLDIASSNAIDLvVAADVE 707
Cdd:pfam00052 79 D-SDGAPVSREDFMMVLANLTAILIRATYST-GSGQVSLSNVSLDSAVPGGSGP-PASWVE 136
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2307-2463 |
2.32e-39 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 144.48 E-value: 2.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2307 SFHFDGSGY-SVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNG 2385
Cdd:cd00110 1 GVSFSGSSYvRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLNDG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2386 TWYKIAFQRNRKQGVLaVIDAYntsnketKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEI 2463
Cdd:cd00110 81 QWHSVSVERNGRSVTL-SVDGE-------RVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKV 150
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2892-3043 |
1.03e-35 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 134.08 E-value: 1.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2892 GTYFDGSGYAALVKEGYKVQSDvNITLEFRTSSQNGVLLGISTA-KVDAIGLELVDGKVLFHVNNGAGRITAAYEpktaT 2970
Cdd:cd00110 1 GVSFSGSSYVRLPTLPAPRTRL-SISFSFRTTSPNGLLLYAGSQnGGDFLALELEDGRLVLRYDLGSGSLVLSSK----T 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2971 VLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:cd00110 76 PLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDL 148
|
|
| LamG |
smart00282 |
Laminin G domain; |
2328-2465 |
1.34e-35 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 132.85 E-value: 1.34e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2328 QIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITL-LTDRRYNNGTWYKIAFQRNRKQGVLaVIDA 2406
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLtSDPTPLNDGQWHRVAVERNGRSVTL-SVDG 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2407 YNTSNketkqGETPGASSDLNRldKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISR 2465
Cdd:smart00282 80 GNRVS-----GESPGGLTILNL--DGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNG 131
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2920-3050 |
4.15e-34 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 128.59 E-value: 4.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2920 FRTSSQNGVLLGIST-AKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKtatvLCDGKWHTLQANKSKHRITLIVDGNAV 2998
Cdd:pfam00054 1 FRTTEPSGLLLYNGTqTERDFLALELRDGRLEVSYDLGSGAAVVRSGDK----LNDGKWHSVELERNGRSGTLSVDGEAR 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 281185471 2999 -GAESPHTQSTSVDTNNPIYVGGYP-AGVKQKCLRSQTSFRGCLRKLALIKSPQ 3050
Cdd:pfam00054 77 pTGESPLGATTDLDVDGPLYVGGLPsLGVKKRRLAISPSFDGCIRDVIVNGKPL 130
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2731-2867 |
1.90e-33 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 127.53 E-value: 1.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2731 SAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGF 2810
Cdd:cd00110 16 PAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLNDGQWHSVSVERNGRSVT 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 2811 ITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNiTHSIPACIGDVTVN 2867
Cdd:cd00110 96 LSVDGERVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPV-SPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2738-2869 |
6.55e-33 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 125.14 E-value: 6.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2738 SVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPAL-LSDGKWHTVKTDYVKRKGFITVDGR 2816
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTpLNDGQWHRVAVERNGRSVTLSVDGG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2817 ESPMVTVVGDGTMLDVEGLFYLGGLPSQyQARKIGNITHSIPACIGDVTVNSK 2869
Cdd:smart00282 81 NRVSGESPGGLTILNLDGPLYLGGLPED-LKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
smart00282 |
Laminin G domain; |
2141-2280 |
1.31e-31 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 121.68 E-value: 1.31e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2141 TLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVkem 2220
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSV--- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2221 ssNQKSPTKTSkSPGTANVLDVNnsTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
Cdd:smart00282 78 --DGGNRVSGE-SPGGLTILNLD--GPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2129-2278 |
2.32e-31 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 121.76 E-value: 2.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2129 AYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDfPIDDNRWHSIHVAR 2208
Cdd:cd00110 11 RLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKT-PLNDGQWHSVSVER 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2209 FGNIGSLSVKEMSSNQKSPTKTSkspgtanvLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLN 2278
Cdd:cd00110 90 NGRSVTLSVDGERVVESGSPGGS--------ALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2915-3043 |
5.14e-31 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 119.75 E-value: 5.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2915 NITLEFRTSSQNGVLLGISTA-KVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTatvLCDGKWHTLQANKSKHRITLIV 2993
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKgGGDYLALELRDGRLVLRYDLGSGPARLTSDPTP---LNDGQWHRVAVERNGRSVTLSV 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 2994 DG-NAVGAESPhTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:smart00282 78 DGgNRVSGESP-GGLTILNLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNL 127
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2146-2283 |
5.14e-30 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 117.03 E-value: 5.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2146 VKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDfPIDDNRWHSIHVARFGNIGSLSVkemssNQK 2225
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGD-KLNDGKWHSVELERNGRSGTLSV-----DGE 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2226 SPTKTSKSPGTANVLDVNnsTLMFVGGLGGQI-KKSPAVKVTHFKGCLGEAFLNGKSIG 2283
Cdd:pfam00054 75 ARPTGESPLGATTDLDVD--GPLYVGGLPSLGvKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2514-2658 |
1.48e-29 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 115.49 E-value: 1.48e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2514 FATTNSSGIILaaLGGDVEKRgdreeahvPFFSVMLIGGNIEVHVNPGDGtglrKALLHAPTgTCSDGQAHSISLVRNRR 2593
Cdd:pfam00054 1 FRTTEPSGLLL--YNGTQTER--------DFLALELRDGRLEVSYDLGSG----AAVVRSGD-KLNDGKWHSVELERNGR 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2594 IITVQLDENNPV--EMKLGTLVesrTINVSN-LYVGGIPE-GEGTSLLTMRRSFHGCIKNLIFNLELLD 2658
Cdd:pfam00054 66 SGTLSVDGEARPtgESPLGATT---DLDVDGpLYVGGLPSlGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2488-2653 |
4.36e-29 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 115.21 E-value: 4.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2488 SVSFLKGGYIELPPKSL-SPESEWLVTFATTNSSGIILAALGGDvekrgdreeaHVPFFSVMLIGGNIEVHVNPGDGTgl 2566
Cdd:cd00110 1 GVSFSGSSYVRLPTLPApRTRLSISFSFRTTSPNGLLLYAGSQN----------GGDFLALELEDGRLVLRYDLGSGS-- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2567 rkALLHAPTgTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINvSNLYVGGIPEGEGTSLLTMRRSFHGC 2646
Cdd:cd00110 69 --LVLSSKT-PLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALLNLD-GPLYLGGLPEDLKSPGLPVSPGFVGC 144
|
....*..
gi 281185471 2647 IKNLIFN 2653
Cdd:cd00110 145 IRDLKVN 151
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2333-2465 |
2.43e-27 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 109.33 E-value: 2.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2333 FNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVidayntSNK 2412
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSV------DGE 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 2413 ETKQGETP-GASSDLNrLDKdPIYVGGLPRSRVVRR-GVTTKSFVGCIKNLEISR 2465
Cdd:pfam00054 75 ARPTGESPlGATTDLD-VDG-PLYVGGLPSLGVKKRrLAISPSFDGCIRDVIVNG 127
|
|
| LamG |
smart00282 |
Laminin G domain; |
2512-2653 |
3.96e-25 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 103.19 E-value: 3.96e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2512 VTFATTNSSGIILAALGGDvekrgdreeaHVPFFSVMLIGGNIEVHVNPGDGTglrkALLHAPTGTCSDGQAHSISLVRN 2591
Cdd:smart00282 4 FSFRTTSPNGLLLYAGSKG----------GGDYLALELRDGRLVLRYDLGSGP----ARLTSDPTPLNDGQWHRVAVERN 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2592 RRIITVQLDENNPVEMKlgTLVESRTINV-SNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFN 2653
Cdd:smart00282 70 GRSVTLSVDGGNRVSGE--SPGGLTILNLdGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVN 130
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
902-948 |
5.44e-15 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 71.23 E-value: 5.44e-15
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL--DSGHGC 948
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
902-948 |
1.80e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 69.65 E-value: 1.80e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGlDSGHGC 948
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
901-949 |
1.85e-14 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 69.69 E-value: 1.85e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDS-GHGCR 949
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
454-500 |
3.72e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 3.72e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
Cdd:pfam00053 1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1044-1092 |
4.66e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 4.66e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 1044 CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDC 1092
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1090-1147 |
3.66e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 63.14 E-value: 3.66e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 1090 CDCDLRGTSGDACNLEqglcgcveeTGACPCKENVFGPQCNECREGTFALRADNPLGC 1147
Cdd:pfam00053 1 CDCNPHGSLSDTCDPE---------TGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1509-1546 |
1.17e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.17e-11
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
951-998 |
1.39e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.39e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 951 CNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
Cdd:pfam00053 1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1591-2122 |
1.65e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1591 LSNLENTTKYLQESLL-----KENMQKDLGKI--KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIER 1663
Cdd:TIGR02168 311 LANLERQLEELEAQLEeleskLDELAEELAELeeKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1664 LQMSITEIMEKTTLNQTLDEDFllpNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDL---LSQIQENYQKPL 1740
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLERL---EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELqeeLERLEEALEELR 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1741 EELEVLKEA---ASHVLSKHNNELKAAEALVREAEAKMQESNHLLLmvnaNLREFSD------KKLHVQEEQNLTSELIV 1811
Cdd:TIGR02168 468 EELEEAEQAldaAERELAQLQARLDSLERLQENLEGFSEGVKALLK----NQSGLSGilgvlsELISVDEGYEAAIEAAL 543
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1812 QGRglIDAAAAQT-DAVQDALEHLEDHQDKLLLWSA-------KIRhhIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLAD 1883
Cdd:TIGR02168 544 GGR--LQAVVVENlNAAKKAIAFLKQNELGRVTFLPldsikgtEIQ--GNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1884 VLYSGL---ENI--------------RNVSL---------------NATSAAYVHY-----NIQSLIEESEELARDAHRT 1926
Cdd:TIGR02168 620 YLLGGVlvvDDLdnalelakklrpgyRIVTLdgdlvrpggvitggsAKTNSSILERrreieELEEKIEELEEKIAELEKA 699
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1927 VTETSLLSESLVSNGKAAVqrssrflKEGNNLSRKLPGIALELSELRNKtnrfQENAVEITRQTNESLLILRAIPKGIRD 2006
Cdd:TIGR02168 700 LAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLEAE----VEQLEERIAQLSKELTELEAEIEELEE 768
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2007 KGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLK 2086
Cdd:TIGR02168 769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
570 580 590
....*....|....*....|....*....|....*.
gi 281185471 2087 PLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSA 2122
Cdd:TIGR02168 849 ELSEDIESLAAEIEELEELIEELESELEALLNERAS 884
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
397-456 |
2.90e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.44 E-value: 2.90e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 397 CNCDPVGSLSSVCikdDLHSdlhngkqpGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGC 456
Cdd:pfam00053 1 CDCNPHGSLSDTC---DPET--------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
951-995 |
3.87e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.02 E-value: 3.87e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 951 CNCSVAGSVSDGC-TDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
Cdd:smart00180 1 CDCDPGGSASGTCdPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1509-1546 |
5.40e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.06 E-value: 5.40e-11
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
848-900 |
8.81e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 59.29 E-value: 8.81e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 848 PCDCSGNvdPSEAGHCDSVTGECLkCLGNTDGAHCERCADGFYGDAVTAKNCR 900
Cdd:cd00055 1 PCDCNGH--GSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1403-1449 |
1.74e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 58.52 E-value: 1.74e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 1403 CSCNNH---SDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYGKVTGSASDC 1449
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
998-1041 |
2.59e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.75 E-value: 2.59e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 998 CDCPH---TQNTCDPETGECVCPPHTQGVKCEECEDGHWGY--DAEVGC 1041
Cdd:pfam00053 1 CDCNPhgsLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
997-1042 |
3.23e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.75 E-value: 3.23e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 997 PCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQ 1042
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGgGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1043-1086 |
4.46e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.36 E-value: 4.46e-10
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 281185471 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD 1086
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
849-895 |
4.76e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.36 E-value: 4.76e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 849 CDCSGNVDPSeaGHCDSVTGECLkCLGNTDGAHCERCADGFYGDAVT 895
Cdd:pfam00053 1 CDCNPHGSLS--DTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSD 44
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1509-1546 |
5.07e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 56.94 E-value: 5.07e-10
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
998-1041 |
5.12e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 56.94 E-value: 5.12e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 998 CDCP---HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEvGC 1041
Cdd:smart00180 1 CDCDpggSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPP-GC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
396-450 |
5.54e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.98 E-value: 5.54e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 396 PCNCDPVGSLSSVCIKDDlhsdlhngkqpGQCPCKEGYTGEKCDRCQLGYKDYPT 450
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGT-----------GQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
741-789 |
6.60e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.98 E-value: 6.60e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 741 PCECHGHAA---ECN-VHGVCIaCAHNTTGVHCEQCLPGFYGEPSRgtPGDCQ 789
Cdd:cd00055 1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
950-996 |
6.73e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.59 E-value: 6.73e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 950 PCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFY--AYQDGSCT 996
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGtGQCECKPNTTGRRCDRCAPGYYglPSQGGGCQ 50
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
397-451 |
3.52e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.52e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 397 CNCDPVGSLSSVCIKDDlhsdlhngkqpGQCPCKEGYTGEKCDRCQLGY--KDYPTC 451
Cdd:smart00180 1 CDCDPGGSASGTCDPDT-----------GQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1044-1087 |
3.80e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.80e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 1044 CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY--RDFPDC 1087
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
454-500 |
4.58e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.24 E-value: 4.58e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNlkeKNPRGC 500
Cdd:smart00180 1 CDCDPGGSASGtcDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1611-2125 |
5.06e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.26 E-value: 5.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1611 QKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKttLNQTLDEDFLLpNS 1690
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYEL-LA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1691 TLQNMQQNGTSLLEimQIRDFTQLHQNATLELKAAEDLLSQIQENyqkpLEELEVLKEAASHVLSKHNNELKAAEALVRE 1770
Cdd:COG1196 296 ELARLEQDIARLEE--RRRELEERLEELEEELAELEEELEELEEE----LEELEEELEEAEEELEEAEAELAEAEEALLE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1771 AEAKMQESNHLL-------LMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLL 1843
Cdd:COG1196 370 AEAELAEAEEELeelaeelLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1844 WSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAA--EFQRLADVLYSGLENIRNVSLNATSAAYVHyNIQSLIEESEELAR 1921
Cdd:COG1196 450 EEAELEEEEEALLELLAELLEEAALLEAALAELleELAEAAARLLLLLEAEADYEGFLEGVKAAL-LLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1922 DAHRTVTETSLLSESLVSNGKAAVQRSSR-------FLKEgNNLSRK--LP------------------------GIALE 1968
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaieYLKA-AKAGRAtfLPldkiraraalaaalargaigaavdLVASD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1969 LSELRNKTNRFQENAVEITRQTnESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNT 2048
Cdd:COG1196 608 LREADARYYVLGDTLLGRTLVA-ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 2049 TLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRD 2125
Cdd:COG1196 687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1090-1147 |
5.10e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.24 E-value: 5.10e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 1090 CDCDLRGTSGDACNLEqglcgcveeTGACPCKENVFGPQCNECREGTFalrADNPLGC 1147
Cdd:smart00180 1 CDCDPGGSASGTCDPD---------TGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
742-788 |
7.22e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 53.90 E-value: 7.22e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 742 CECHGHAA---ECNVH-GVCIaCAHNTTGVHCEQCLPGFYGEPSrGTPGDC 788
Cdd:pfam00053 1 CDCNPHGSlsdTCDPEtGQCL-CKPGVTGRHCDRCKPGYYGLPS-DPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
453-500 |
8.83e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 53.51 E-value: 8.83e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 453 SCGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEkNPRGC 500
Cdd:cd00055 1 PCDCNGHGSLSGQcdPGTGQCECKPNTTGRRCDRCAPGYYGLPS-QGGGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1089-1147 |
2.05e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.74 E-value: 2.05e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 1089 PCDCDLRGTSGDACNleqglcgcvEETGACPCKENVFGPQCNECREGTFALrADNPLGC 1147
Cdd:cd00055 1 PCDCNGHGSLSGQCD---------PGTGQCECKPNTTGRRCDRCAPGYYGL-PSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
791-846 |
2.39e-08 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 52.36 E-value: 2.39e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 281185471 791 CACPLTIASnnfSPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNPTVPGESC 846
Cdd:pfam00053 1 CDCNPHGSL---SDTCDPETG---QCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1593-1842 |
3.54e-08 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 59.08 E-value: 3.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1593 NLENTTKYLQESLlkENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIM 1672
Cdd:PRK04778 253 DIEKEIQDLKEQI--DENLALLEELDLDEAEEKNEEIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELK 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1673 EKTTLnqtLDEDFLLPNSTLQNMQQNGTSLLEIMqiRDFTQLHQNatleLKAAEDLLSQIQENYQKPLEELEVLKEaaSH 1752
Cdd:PRK04778 331 EEIDR---VKQSYTLNESELESVRQLEKQLESLE--KQYDEITER----IAEQEIAYSELQEELEEILKQLEEIEK--EQ 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1753 V-LSKHNNELKAAEALVREAEAKMQE--SNHLLLMVNANL----REFSDKKLHVQEE-QNLTSELiVQGRGLIDAAAAQT 1824
Cdd:PRK04778 400 EkLSEMLQGLRKDELEAREKLERYRNklHEIKRYLEKSNLpglpEDYLEMFFEVSDEiEALAEEL-EEKPINMEAVNRLL 478
|
250
....*....|....*...
gi 281185471 1825 DAVQDALEHLEDHQDKLL 1842
Cdd:PRK04778 479 EEATEDVETLEEETEELV 496
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1402-1440 |
6.32e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 51.20 E-value: 6.32e-08
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 281185471 1402 PCSCNNH---SDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYG 1440
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYG 41
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
270-317 |
1.34e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.43 E-value: 1.34e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 270 CICYGHAS---SCpwDETTkkLQCQCEHNTCGESCNRCCPGYHQQPWRPGT 317
Cdd:cd00055 2 CDCNGHGSlsgQC--DPGT--GQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1452-1506 |
1.58e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 50.04 E-value: 1.58e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 1452 CACPHSppASFSPTCVLEGdhdFRCDaCLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
Cdd:pfam00053 1 CDCNPH--GSLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
849-892 |
2.09e-07 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 49.62 E-value: 2.09e-07
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 281185471 849 CDCsgNVDPSEAGHCDSVTGECLkCLGNTDGAHCERCADGFYGD 892
Cdd:smart00180 1 CDC--DPGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1607-1828 |
3.07e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 55.61 E-value: 3.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1607 KENMQKDLGKI--KLEGVAEETDNLQKKLTRMlasTQKVNRATERIfKESQDlaiAIERLQmsiTEIMEkttLNQTLDED 1684
Cdd:COG3883 18 IQAKQKELSELqaELEAAQAELDALQAELEEL---NEEYNELQAEL-EALQA---EIDKLQ---AEIAE---AEAEIEER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1685 FLLPNSTLQNMQQNGTS---LLEIMQIRDFTQLHQNATLeLKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL 1761
Cdd:COG3883 85 REELGERARALYRSGGSvsyLDVLLGSESFSDFLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 1762 KAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQ 1828
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1403-1441 |
1.02e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 47.69 E-value: 1.02e-06
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 281185471 1403 CSCN---NHSDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYGK 1441
Cdd:smart00180 1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
742-783 |
1.21e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 47.31 E-value: 1.21e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 742 CECH--GHAAE-CN-VHGVCIaCAHNTTGVHCEQCLPGFYGEPSRG 783
Cdd:smart00180 1 CDCDpgGSASGtCDpDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1591-1855 |
2.48e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1591 LSNLENTTKYLQESLlkenmqkDLGKIKLEGVAEETDNLQKKL----TRMLASTQKVNRATE---RIFKESQDLAIAIER 1663
Cdd:TIGR02168 679 IEELEEKIEELEEKI-------AELEKALAELRKELEELEEELeqlrKELEELSRQISALRKdlaRLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1664 LQMSITEIM-EKTTLNQTLDEDFLLPNSTLQNMQQngtslLEiMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEE 1742
Cdd:TIGR02168 752 LSKELTELEaEIEELEERLEEAEEELAEAEAEIEE-----LE-AQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1743 LEVLK------------------------EAASHVLS-------KHNNELKAAEALVREAEAKMQESNHLLLMVNANLRE 1791
Cdd:TIGR02168 826 LESLErriaaterrledleeqieelsediESLAAEIEeleelieELESELEALLNERASLEEALALLRSELEELSEELRE 905
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 1792 FSDKKL-----------HVQEEQNLTSELIVQGRGLIDAAAAQtdaVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855
Cdd:TIGR02168 906 LESKRSelrreleelreKLAQLELRLEGLEVRIDNLQERLSEE---YSLTLEEAEALENKIEDDEEEARRRLKRL 977
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
790-844 |
5.47e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 45.81 E-value: 5.47e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 790 PCACPLTIASNnfsPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNPTVPGE 844
Cdd:cd00055 1 PCDCNGHGSLS---GQCDPGTG---QCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
791-839 |
2.48e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.84 E-value: 2.48e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 791 CACPLtiaSNNFSPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNP 839
Cdd:smart00180 1 CDCDP---GGSASGTCDPDTG---QCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| BAR |
smart00721 |
BAR domain; |
1609-1841 |
3.63e-05 |
|
BAR domain;
Pssm-ID: 214787 [Multi-domain] Cd Length: 239 Bit Score: 47.76 E-value: 3.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1609 NMQKDLGKIK---LE--GVAEET------DNLQKKLTRMLASTQKVNRATERiFKESQDLAIAIERLQMSITEIMEKTTL 1677
Cdd:smart00721 1 GFKKQFNRAKqkvGEkvGKAEKTkldedfEELERRFDTTEAEIEKLQKDTKL-YLQPNPAVRAKLASQKKLSKSLGEVYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1678 NQTLDEDFLLPNSTLQNMQQNGTSLLEIMQI-RDFTQLHQNATLEL-KAAEDLLSQIQENYQKpLEELEVLKEAASHVLS 1755
Cdd:smart00721 80 GGDDGEGLGADSSYGKALDKLGEALKKLLQVeESLSQVKRTFILPLlNFLLGEFKEIKKARKK-LERKLLDYDSARHKLK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1756 KH--------NNELKAAEALVREAEAKMQESNHLLLmvnANLREFSDKK--LHVQEEQNLtselivqgrglidaAAAQTD 1825
Cdd:smart00721 159 KAkkskekkkDEKLAKAEEELRKAKQEFEESNAQLV---EELPQLVASRvdFFVNCLQAL--------------IEAQLN 221
|
250
....*....|....*.
gi 281185471 1826 AVQDALEHLEDHQDKL 1841
Cdd:smart00721 222 FHRESYKLLQQLQQQL 237
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
1763-2102 |
3.46e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 46.17 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1763 AAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLL 1842
Cdd:COG0840 28 ALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1843 LWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARD 1922
Cdd:COG0840 108 ALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAA 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1923 AHRTVTETSLLSESLVSNGKAAVQRSSRFLKE--GNNLSRKLP-GIALELSELRNKTNRFQENAVEITRQTNESLLILRA 1999
Cdd:COG0840 188 LLALVALAIILALLLSRSITRPLRELLEVLERiaEGDLTVRIDvDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVAS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2000 IPKGIRdkgAKTKELATSASQSAvSTLRDVAGLSQELlntSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQAN 2079
Cdd:COG0840 268 ASEELA---ASAEELAAGAEEQA-ASLEETAAAMEEL---SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIE 340
|
330 340
....*....|....*....|....*..
gi 281185471 2080 LLFDRLKPL----KMLEENlSRNLSEI 2102
Cdd:COG0840 341 EIRESVEETaetiEELGES-SQEIGEI 366
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
289-313 |
3.81e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.37 E-value: 3.81e-04
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1595-2131 |
3.88e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1595 ENTTKYLQ-----ESLLKENmQKDLGKI---------KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIA 1660
Cdd:PRK03918 179 ERLEKFIKrteniEELIKEK-EKELEEVlreineissELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1661 IERLQMSITEIMEKTTLNQTLDEDFllpnSTLQNMQQNGTSLLEIMQIRD-FTQLHQNATLELKAAEDLLSQIQ------ 1733
Cdd:PRK03918 258 EEKIRELEERIEELKKEIEELEEKV----KELKELKEKAEEYIKLSEFYEeYLDELREIEKRLSRLEEEINGIEerikel 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1734 ENYQKPLEELEVLKEAashvLSKHNNELKAAEALVREAEAKMQESNHL--------LLMVNANLREFSDKKLHVQEE-QN 1804
Cdd:PRK03918 334 EEKEERLEELKKKLKE----LEKRLEELEERHELYEEAKAKKEELERLkkrltgltPEKLEKELEELEKAKEEIEEEiSK 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1805 LTSElivqgRGLIDAAAAQtdaVQDALEHLEDHQDKLLLWSAKI-RHHIDDLvmhMSQrnavdlvYRAE--DHAAEFQRL 1881
Cdd:PRK03918 410 ITAR-----IGELKKEIKE---LKKAIEELKKAKGKCPVCGRELtEEHRKEL---LEE-------YTAElkRIEKELKEI 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1882 ADVLYSGLENIRNVS--LNATSAAYVHYNIQSLIEE---------SEELARDA--HRTVTETSLLSESLVSNGKAAVQRS 1948
Cdd:PRK03918 472 EEKERKLRKELRELEkvLKKESELIKLKELAEQLKEleeklkkynLEELEKKAeeYEKLKEKLIKLKGEIKSLKKELEKL 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1949 SRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESL-------LILRAIPKGIRDKGAKTKELATSASQS 2021
Cdd:PRK03918 552 EELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELepfyneyLELKDAEKELEREEKELKKLEEELDKA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2022 avstLRDVAGLSQELLNTSASLSRVNTTL-RETHQLLQDSTM--ATLLAGrkvKDVEIQAnlLFDRLKPLKMLEENLSRN 2098
Cdd:PRK03918 632 ----FEELAETEKRLEELRKELEELEKKYsEEEYEELREEYLelSRELAG---LRAELEE--LEKRREEIKKTLEKLKEE 702
|
570 580 590
....*....|....*....|....*....|....*.
gi 281185471 2099 LSEIKllisQARKQAASIKVA---VSADRDCIRAYQ 2131
Cdd:PRK03918 703 LEERE----KAKKELEKLEKAlerVEELREKVKKYK 734
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1452-1507 |
1.07e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 39.26 E-value: 1.07e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 281185471 1452 CACPhsPPASFSPTCVlegDHDFRCDaCLLGYEGKHCERCSSSYYGNPQTPGGsCQ 1507
Cdd:cd00055 2 CDCN--GHGSLSGQCD---PGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG-CQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
270-316 |
2.75e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.10 E-value: 2.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 270 CICYGHAS---SCpwDETTkkLQCQCEHNTCGESCNRCCPGYHQQPWRPG 316
Cdd:pfam00053 1 CDCNPHGSlsdTC--DPET--GQCLCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
16-268 |
8.66e-103 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
Pssm-ID: 214532 Cd Length: 238 Bit Score: 329.71 E-value: 8.66e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 16 QCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVehvpGRPVRNPQCRICDGNsaNPRERHPISHAIDGTN----N 91
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLV----GHTEQGKKCDYCDAR--NPRRSHPAENLTDGNNpnnpT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 92 WWQSPSIQNGReyHWVTITLDLRQVFQVAYVIIKAAnAPRPGNWILERSLDGTTFSPWQYYAvsdSECLSRYNITPRRGP 171
Cdd:smart00136 75 WWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGPI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 172 PTYrADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLShrepkel 249
Cdd:smart00136 149 TKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDFdnSPVLQEWVTATNIRVRLTRLRTLGDELMDDR------- 220
|
250
....*....|....*....
gi 281185471 250 dPIVTRRYYYSIKDISVGG 268
Cdd:smart00136 221 -PEVTRRYYYAISDIAVGG 238
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
1575-1830 |
9.35e-100 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 322.05 E-value: 9.35e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1575 VLSLN-LTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK---LEGVAEETDNLQKKLTRMLASTQKVNRATERI 1650
Cdd:pfam06008 1 LLSLNsLTGALPAPYKINYNLENLTKQLQEYLSPENAHKIQIEILekeLSSLAQETEELQKKATQTLAKAQQVNAESERT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1651 FKESQDLAIAIERLQMSITEIMEKT-TLNQtldEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLL 1729
Cdd:pfam06008 81 LGHAKELAEAIKNLIDNIKEINEKVaTLGE---NDFALPSSDLSRMLAEAQRMLGEIRSRDFGTQLQNAEAELKAAQDLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1730 SQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSEL 1809
Cdd:pfam06008 158 SRIQTWFQSPQEENKALANALRDSLAEYEAKLSDLRELLREAAAKTRDANRLNLANQANLREFQRKKEEVSEQKNQLEET 237
|
250 260
....*....|....*....|.
gi 281185471 1810 IVQGRGLIDAAAAQTDAVQDA 1830
Cdd:pfam06008 238 LKTARDSLDAANLLLQEIDDA 258
|
|
| Laminin_N |
pfam00055 |
Laminin N-terminal (Domain VI); |
22-268 |
1.26e-87 |
|
Laminin N-terminal (Domain VI);
Pssm-ID: 459653 Cd Length: 230 Bit Score: 286.02 E-value: 1.26e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 22 LFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGrpvrnPQCRICDgnSANPRERHPISHAIDGTNN----WWQSPS 97
Cdd:pfam00055 1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSGLEGG-----KKCFICD--SRDPHNSHPPSNLTDSNNGtnetWWQSET 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 98 IQngREYHWVTITLDLRQVFQVAYVIIKAAnAPRPGNWILERSLD-GTTFSPWQYYAvsdSECLSRYNITPRrgPPTYRA 176
Cdd:pfam00055 74 GV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRPSG--PSRGIK 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 177 DDEVICTSYYSRLVPLEHGEIHTSLINGRPSA--DDLSPKLLEFTSARYIRLRLQRIRTLNADLMTlshrepkelDPIVT 254
Cdd:pfam00055 146 DDEVICTSEYSDISPLTGGEVIFSTLEGRPSAniFDYSPELQDWLTATNIRIRLLRLHTLGDELLD---------DPSVL 216
|
250
....*....|....
gi 281185471 255 RRYYYSIKDISVGG 268
Cdd:pfam00055 217 RKYYYAISDISVGG 230
|
|
| Laminin_II |
pfam06009 |
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 ... |
2011-2145 |
8.12e-57 |
|
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 368703 [Multi-domain] Cd Length: 138 Bit Score: 193.86 E-value: 8.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2011 TKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKM 2090
Cdd:pfam06009 1 SKELAREANETAKEVLEQLAPLSQNLENTSEKLSGINRSLEETNELVNDANKALDDAGRSVKKLEELAPDLLDKLKPLKQ 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2091 LEEN---LSRNLSEIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLN 2145
Cdd:pfam06009 81 LEVNsssLSDNISRIKELIAQARKAANSIKVSVSFDGDSIVELRPPISVTDLAAYTSL 138
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
1218-1344 |
1.00e-50 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 176.31 E-value: 1.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYf 1297
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSLNSEPDVILEGNGLRLSYSSPDQPPPDPGQEQTYSVRLHEENWRD- 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 281185471 1298 nsVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Cdd:pfam00052 80 --SDGAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAV 124
|
|
| LamB |
smart00281 |
Laminin B domain; |
1213-1344 |
1.76e-49 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 172.45 E-value: 1.76e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1213 RAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGvGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEqeVAMREN 1292
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRG-GTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVE--VRFREE 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 281185471 1293 FWKYFNsvsEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
Cdd:smart00281 78 NWQYYG---GRPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAV 126
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2743-2872 |
4.30e-47 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 165.95 E-value: 4.30e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2743 IRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVT 2822
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSVDGEARPTGE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 2823 VVGDGTM-LDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLD 2872
Cdd:pfam00054 81 SPLGATTdLDVDGPLYVGGLPSLGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| LamB |
smart00281 |
Laminin B domain; |
563-695 |
3.88e-45 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 160.12 E-value: 3.88e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 563 LAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPvetVDSNLMSHADVIIKGNGLTLSTQAEGlSLQPYEEYLNVVRLVP 642
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGR---RGGTHVSAPDVILEGNGLRISHPAEG-PPLPDELTTVEVRFRE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 643 ENFQDFHsKRQIDRDQLMTVLANVTHLLIRANYnSAKMALYRLESVSLDIASS 695
Cdd:smart00281 77 ENWQYYG-GRPVTREDLMMVLANLTAILIRATY-SQQMAGSRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
568-707 |
2.52e-43 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 155.12 E-value: 2.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 568 YWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETvdSNLMSHADVIIKGNGLTLST-QAEGLSLQPYEEYLNVVRLVPENFQ 646
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSEPDVILEGNGLRLSYsSPDQPPPDPGQEQTYSVRLHEENWR 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281185471 647 DfHSKRQIDRDQLMTVLANVTHLLIRANYNSaKMALYRLESVSLDIASSNAIDLvVAADVE 707
Cdd:pfam00052 79 D-SDGAPVSREDFMMVLANLTAILIRATYST-GSGQVSLSNVSLDSAVPGGSGP-PASWVE 136
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2307-2463 |
2.32e-39 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 144.48 E-value: 2.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2307 SFHFDGSGY-SVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNG 2385
Cdd:cd00110 1 GVSFSGSSYvRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLNDG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 2386 TWYKIAFQRNRKQGVLaVIDAYntsnketKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEI 2463
Cdd:cd00110 81 QWHSVSVERNGRSVTL-SVDGE-------RVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKV 150
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2892-3043 |
1.03e-35 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 134.08 E-value: 1.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2892 GTYFDGSGYAALVKEGYKVQSDvNITLEFRTSSQNGVLLGISTA-KVDAIGLELVDGKVLFHVNNGAGRITAAYEpktaT 2970
Cdd:cd00110 1 GVSFSGSSYVRLPTLPAPRTRL-SISFSFRTTSPNGLLLYAGSQnGGDFLALELEDGRLVLRYDLGSGSLVLSSK----T 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2971 VLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:cd00110 76 PLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDL 148
|
|
| LamG |
smart00282 |
Laminin G domain; |
2328-2465 |
1.34e-35 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 132.85 E-value: 1.34e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2328 QIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITL-LTDRRYNNGTWYKIAFQRNRKQGVLaVIDA 2406
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLtSDPTPLNDGQWHRVAVERNGRSVTL-SVDG 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2407 YNTSNketkqGETPGASSDLNRldKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISR 2465
Cdd:smart00282 80 GNRVS-----GESPGGLTILNL--DGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNG 131
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2920-3050 |
4.15e-34 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 128.59 E-value: 4.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2920 FRTSSQNGVLLGIST-AKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKtatvLCDGKWHTLQANKSKHRITLIVDGNAV 2998
Cdd:pfam00054 1 FRTTEPSGLLLYNGTqTERDFLALELRDGRLEVSYDLGSGAAVVRSGDK----LNDGKWHSVELERNGRSGTLSVDGEAR 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 281185471 2999 -GAESPHTQSTSVDTNNPIYVGGYP-AGVKQKCLRSQTSFRGCLRKLALIKSPQ 3050
Cdd:pfam00054 77 pTGESPLGATTDLDVDGPLYVGGLPsLGVKKRRLAISPSFDGCIRDVIVNGKPL 130
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2731-2867 |
1.90e-33 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 127.53 E-value: 1.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2731 SAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGF 2810
Cdd:cd00110 16 PAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLNDGQWHSVSVERNGRSVT 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 2811 ITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNiTHSIPACIGDVTVN 2867
Cdd:cd00110 96 LSVDGERVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPV-SPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2738-2869 |
6.55e-33 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 125.14 E-value: 6.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2738 SVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPAL-LSDGKWHTVKTDYVKRKGFITVDGR 2816
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTpLNDGQWHRVAVERNGRSVTLSVDGG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2817 ESPMVTVVGDGTMLDVEGLFYLGGLPSQyQARKIGNITHSIPACIGDVTVNSK 2869
Cdd:smart00282 81 NRVSGESPGGLTILNLDGPLYLGGLPED-LKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
smart00282 |
Laminin G domain; |
2141-2280 |
1.31e-31 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 121.68 E-value: 1.31e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2141 TLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVkem 2220
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSV--- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2221 ssNQKSPTKTSkSPGTANVLDVNnsTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
Cdd:smart00282 78 --DGGNRVSGE-SPGGLTILNLD--GPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2129-2278 |
2.32e-31 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 121.76 E-value: 2.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2129 AYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDfPIDDNRWHSIHVAR 2208
Cdd:cd00110 11 RLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKT-PLNDGQWHSVSVER 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2209 FGNIGSLSVKEMSSNQKSPTKTSkspgtanvLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLN 2278
Cdd:cd00110 90 NGRSVTLSVDGERVVESGSPGGS--------ALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2915-3043 |
5.14e-31 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 119.75 E-value: 5.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2915 NITLEFRTSSQNGVLLGISTA-KVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTatvLCDGKWHTLQANKSKHRITLIV 2993
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSKgGGDYLALELRDGRLVLRYDLGSGPARLTSDPTP---LNDGQWHRVAVERNGRSVTLSV 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 2994 DG-NAVGAESPhTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:smart00282 78 DGgNRVSGESP-GGLTILNLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNL 127
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2146-2283 |
5.14e-30 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 117.03 E-value: 5.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2146 VKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDfPIDDNRWHSIHVARFGNIGSLSVkemssNQK 2225
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGD-KLNDGKWHSVELERNGRSGTLSV-----DGE 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2226 SPTKTSKSPGTANVLDVNnsTLMFVGGLGGQI-KKSPAVKVTHFKGCLGEAFLNGKSIG 2283
Cdd:pfam00054 75 ARPTGESPLGATTDLDVD--GPLYVGGLPSLGvKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2514-2658 |
1.48e-29 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 115.49 E-value: 1.48e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2514 FATTNSSGIILaaLGGDVEKRgdreeahvPFFSVMLIGGNIEVHVNPGDGtglrKALLHAPTgTCSDGQAHSISLVRNRR 2593
Cdd:pfam00054 1 FRTTEPSGLLL--YNGTQTER--------DFLALELRDGRLEVSYDLGSG----AAVVRSGD-KLNDGKWHSVELERNGR 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 2594 IITVQLDENNPV--EMKLGTLVesrTINVSN-LYVGGIPE-GEGTSLLTMRRSFHGCIKNLIFNLELLD 2658
Cdd:pfam00054 66 SGTLSVDGEARPtgESPLGATT---DLDVDGpLYVGGLPSlGVKKRRLAISPSFDGCIRDVIVNGKPLD 131
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2488-2653 |
4.36e-29 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 115.21 E-value: 4.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2488 SVSFLKGGYIELPPKSL-SPESEWLVTFATTNSSGIILAALGGDvekrgdreeaHVPFFSVMLIGGNIEVHVNPGDGTgl 2566
Cdd:cd00110 1 GVSFSGSSYVRLPTLPApRTRLSISFSFRTTSPNGLLLYAGSQN----------GGDFLALELEDGRLVLRYDLGSGS-- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2567 rkALLHAPTgTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINvSNLYVGGIPEGEGTSLLTMRRSFHGC 2646
Cdd:cd00110 69 --LVLSSKT-PLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALLNLD-GPLYLGGLPEDLKSPGLPVSPGFVGC 144
|
....*..
gi 281185471 2647 IKNLIFN 2653
Cdd:cd00110 145 IRDLKVN 151
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2333-2465 |
2.43e-27 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 109.33 E-value: 2.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2333 FNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVidayntSNK 2412
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSV------DGE 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 2413 ETKQGETP-GASSDLNrLDKdPIYVGGLPRSRVVRR-GVTTKSFVGCIKNLEISR 2465
Cdd:pfam00054 75 ARPTGESPlGATTDLD-VDG-PLYVGGLPSLGVKKRrLAISPSFDGCIRDVIVNG 127
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2920-3043 |
2.78e-27 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 109.05 E-value: 2.78e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2920 FRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTatvLCDGKWHTLQANKSKHRITLIVDGNAVG 2999
Cdd:pfam02210 1 FRTRQPNGLLLYAGGGGSDFLALELVNGRLVLRYDLGSGPESLLSSGKN---LNDGQWHSVRVERNGNTLTLSVDGQTVV 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 281185471 3000 AESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKL 3043
Cdd:pfam02210 78 SSLPPGESLLLNLNGPLYLGGLPPLLLLPALPVRAGFVGCIRDV 121
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2333-2463 |
1.50e-25 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 104.04 E-value: 1.50e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2333 FNTFSPNGLLLYLGSyGTKDFLSIELFRGRVKVMTDLGSGPITLL-TDRRYNNGTWYKIAFQRNRKQGVLAViDayntsN 2411
Cdd:pfam02210 1 FRTRQPNGLLLYAGG-GGSDFLALELVNGRLVLRYDLGSGPESLLsSGKNLNDGQWHSVRVERNGNTLTLSV-D-----G 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 281185471 2412 KETKQGETPGASSDLNrlDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEI 2463
Cdd:pfam02210 74 QTVVSSLPPGESLLLN--LNGPLYLGGLPPLLLLPALPVRAGFVGCIRDVRV 123
|
|
| LamG |
smart00282 |
Laminin G domain; |
2512-2653 |
3.96e-25 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 103.19 E-value: 3.96e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2512 VTFATTNSSGIILAALGGDvekrgdreeaHVPFFSVMLIGGNIEVHVNPGDGTglrkALLHAPTGTCSDGQAHSISLVRN 2591
Cdd:smart00282 4 FSFRTTSPNGLLLYAGSKG----------GGDYLALELRDGRLVLRYDLGSGP----ARLTSDPTPLNDGQWHRVAVERN 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281185471 2592 RRIITVQLDENNPVEMKlgTLVESRTINV-SNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFN 2653
Cdd:smart00282 70 GRSVTLSVDGGNRVSGE--SPGGLTILNLdGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVN 130
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2146-2280 |
2.76e-22 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 94.79 E-value: 2.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2146 VKTQEPDNLLFYLGSSTaSDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVkemssnQK 2225
Cdd:pfam02210 1 FRTRQPNGLLLYAGGGG-SDFLALELVNGRLVLRYDLGSGPESLLSSGKNLNDGQWHSVRVERNGNTLTLSV------DG 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 2226 SPTKTSKSPGTANVLDVNNStlMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
Cdd:pfam02210 74 QTVVSSLPPGESLLLNLNGP--LYLGGLPPLLLLPALPVRAGFVGCIRDVRVNGE 126
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2743-2869 |
4.13e-21 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 91.33 E-value: 4.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2743 IRTFASSGLIYYmAHQNQADYAVLQLHGGRLHFMFDLGKGRTKV-SHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMV 2821
Cdd:pfam02210 1 FRTRQPNGLLLY-AGGGGSDFLALELVNGRLVLRYDLGSGPESLlSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSS 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 281185471 2822 TVVGDGTMLDVEGLFYLGGLPSQYQARKIGNiTHSIPACIGDVTVNSK 2869
Cdd:pfam02210 80 LPPGESLLLNLNGPLYLGGLPPLLLLPALPV-RAGFVGCIRDVRVNGE 126
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2514-2653 |
1.49e-18 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 84.01 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2514 FATTNSSGIILAALGGdvekRGDreeahvpFFSVMLIGGNIEVHVNPGDGTglrkALLHAPTGTCSDGQAHSISLVRNRR 2593
Cdd:pfam02210 1 FRTRQPNGLLLYAGGG----GSD-------FLALELVNGRLVLRYDLGSGP----ESLLSSGKNLNDGQWHSVRVERNGN 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2594 IITVQLDENNPVEMKLGTLVESRTINvSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFN 2653
Cdd:pfam02210 66 TLTLSVDGQTVVSSLPPGESLLLNLN-GPLYLGGLPPLLLLPALPVRAGFVGCIRDVRVN 124
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
902-948 |
5.44e-15 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 71.23 E-value: 5.44e-15
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL--DSGHGC 948
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
902-948 |
1.80e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 69.65 E-value: 1.80e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGlDSGHGC 948
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
901-949 |
1.85e-14 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 69.69 E-value: 1.85e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDS-GHGCR 949
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
454-500 |
3.72e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 3.72e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
Cdd:pfam00053 1 CDCNPHGSLSDtcDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1044-1092 |
4.66e-13 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 65.84 E-value: 4.66e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 1044 CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDC 1092
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1090-1147 |
3.66e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 63.14 E-value: 3.66e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 1090 CDCDLRGTSGDACNLEqglcgcveeTGACPCKENVFGPQCNECREGTFALRADNPLGC 1147
Cdd:pfam00053 1 CDCNPHGSLSDTCDPE---------TGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1509-1546 |
1.17e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.17e-11
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
951-998 |
1.39e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 61.60 E-value: 1.39e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 951 CNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
Cdd:pfam00053 1 CDCNPHGSLSDTCDPEtGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1591-2122 |
1.65e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1591 LSNLENTTKYLQESLL-----KENMQKDLGKI--KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIER 1663
Cdd:TIGR02168 311 LANLERQLEELEAQLEeleskLDELAEELAELeeKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1664 LQMSITEIMEKTTLNQTLDEDFllpNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDL---LSQIQENYQKPL 1740
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLERL---EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELqeeLERLEEALEELR 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1741 EELEVLKEA---ASHVLSKHNNELKAAEALVREAEAKMQESNHLLLmvnaNLREFSD------KKLHVQEEQNLTSELIV 1811
Cdd:TIGR02168 468 EELEEAEQAldaAERELAQLQARLDSLERLQENLEGFSEGVKALLK----NQSGLSGilgvlsELISVDEGYEAAIEAAL 543
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1812 QGRglIDAAAAQT-DAVQDALEHLEDHQDKLLLWSA-------KIRhhIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLAD 1883
Cdd:TIGR02168 544 GGR--LQAVVVENlNAAKKAIAFLKQNELGRVTFLPldsikgtEIQ--GNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1884 VLYSGL---ENI--------------RNVSL---------------NATSAAYVHY-----NIQSLIEESEELARDAHRT 1926
Cdd:TIGR02168 620 YLLGGVlvvDDLdnalelakklrpgyRIVTLdgdlvrpggvitggsAKTNSSILERrreieELEEKIEELEEKIAELEKA 699
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1927 VTETSLLSESLVSNGKAAVqrssrflKEGNNLSRKLPGIALELSELRNKtnrfQENAVEITRQTNESLLILRAIPKGIRD 2006
Cdd:TIGR02168 700 LAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLEAE----VEQLEERIAQLSKELTELEAEIEELEE 768
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2007 KGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLK 2086
Cdd:TIGR02168 769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
570 580 590
....*....|....*....|....*....|....*.
gi 281185471 2087 PLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSA 2122
Cdd:TIGR02168 849 ELSEDIESLAAEIEELEELIEELESELEALLNERAS 884
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
397-456 |
2.90e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.44 E-value: 2.90e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 397 CNCDPVGSLSSVCikdDLHSdlhngkqpGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGC 456
Cdd:pfam00053 1 CDCNPHGSLSDTC---DPET--------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
951-995 |
3.87e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.02 E-value: 3.87e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 951 CNCSVAGSVSDGC-TDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
Cdd:smart00180 1 CDCDPGGSASGTCdPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1509-1546 |
5.40e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.06 E-value: 5.40e-11
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
848-900 |
8.81e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 59.29 E-value: 8.81e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 848 PCDCSGNvdPSEAGHCDSVTGECLkCLGNTDGAHCERCADGFYGDAVTAKNCR 900
Cdd:cd00055 1 PCDCNGH--GSLSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1403-1449 |
1.74e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 58.52 E-value: 1.74e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 1403 CSCNNH---SDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYGKVTGSASDC 1449
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
998-1041 |
2.59e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.75 E-value: 2.59e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 998 CDCPH---TQNTCDPETGECVCPPHTQGVKCEECEDGHWGY--DAEVGC 1041
Cdd:pfam00053 1 CDCNPhgsLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLpsDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
997-1042 |
3.23e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.75 E-value: 3.23e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 997 PCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQ 1042
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGgGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1043-1086 |
4.46e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.36 E-value: 4.46e-10
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 281185471 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD 1086
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
849-895 |
4.76e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.36 E-value: 4.76e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 849 CDCSGNVDPSeaGHCDSVTGECLkCLGNTDGAHCERCADGFYGDAVT 895
Cdd:pfam00053 1 CDCNPHGSLS--DTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSD 44
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1509-1546 |
5.07e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 56.94 E-value: 5.07e-10
10 20 30
....*....|....*....|....*....|....*...
gi 281185471 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
998-1041 |
5.12e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 56.94 E-value: 5.12e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 281185471 998 CDCP---HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEvGC 1041
Cdd:smart00180 1 CDCDpggSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPP-GC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
396-450 |
5.54e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.98 E-value: 5.54e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 396 PCNCDPVGSLSSVCIKDDlhsdlhngkqpGQCPCKEGYTGEKCDRCQLGYKDYPT 450
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGT-----------GQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
741-789 |
6.60e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.98 E-value: 6.60e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 281185471 741 PCECHGHAA---ECN-VHGVCIaCAHNTTGVHCEQCLPGFYGEPSRgtPGDCQ 789
Cdd:cd00055 1 PCDCNGHGSlsgQCDpGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQ--GGGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
950-996 |
6.73e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.59 E-value: 6.73e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 950 PCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFY--AYQDGSCT 996
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGtGQCECKPNTTGRRCDRCAPGYYglPSQGGGCQ 50
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
397-451 |
3.52e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.52e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 397 CNCDPVGSLSSVCIKDDlhsdlhngkqpGQCPCKEGYTGEKCDRCQLGY--KDYPTC 451
Cdd:smart00180 1 CDCDPGGSASGTCDPDT-----------GQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1044-1087 |
3.80e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.80e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 1044 CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY--RDFPDC 1087
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
454-500 |
4.58e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.24 E-value: 4.58e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNlkeKNPRGC 500
Cdd:smart00180 1 CDCDPGGSASGtcDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1611-2125 |
5.06e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.26 E-value: 5.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1611 QKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKttLNQTLDEDFLLpNS 1690
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYEL-LA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1691 TLQNMQQNGTSLLEimQIRDFTQLHQNATLELKAAEDLLSQIQENyqkpLEELEVLKEAASHVLSKHNNELKAAEALVRE 1770
Cdd:COG1196 296 ELARLEQDIARLEE--RRRELEERLEELEEELAELEEELEELEEE----LEELEEELEEAEEELEEAEAELAEAEEALLE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1771 AEAKMQESNHLL-------LMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLL 1843
Cdd:COG1196 370 AEAELAEAEEELeelaeelLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1844 WSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAA--EFQRLADVLYSGLENIRNVSLNATSAAYVHyNIQSLIEESEELAR 1921
Cdd:COG1196 450 EEAELEEEEEALLELLAELLEEAALLEAALAELleELAEAAARLLLLLEAEADYEGFLEGVKAAL-LLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1922 DAHRTVTETSLLSESLVSNGKAAVQRSSR-------FLKEgNNLSRK--LP------------------------GIALE 1968
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaieYLKA-AKAGRAtfLPldkiraraalaaalargaigaavdLVASD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1969 LSELRNKTNRFQENAVEITRQTnESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNT 2048
Cdd:COG1196 608 LREADARYYVLGDTLLGRTLVA-ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 2049 TLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRD 2125
Cdd:COG1196 687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1090-1147 |
5.10e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.24 E-value: 5.10e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 281185471 1090 CDCDLRGTSGDACNLEqglcgcveeTGACPCKENVFGPQCNECREGTFalrADNPLGC 1147
Cdd:smart00180 1 CDCDPGGSASGTCDPD---------TGQCECKPNVTGRRCDRCAPGYY---GDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
742-788 |
7.22e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 53.90 E-value: 7.22e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 742 CECHGHAA---ECNVH-GVCIaCAHNTTGVHCEQCLPGFYGEPSrGTPGDC 788
Cdd:pfam00053 1 CDCNPHGSlsdTCDPEtGQCL-CKPGVTGRHCDRCKPGYYGLPS-DPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
453-500 |
8.83e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 53.51 E-value: 8.83e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 453 SCGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEkNPRGC 500
Cdd:cd00055 1 PCDCNGHGSLSGQcdPGTGQCECKPNTTGRRCDRCAPGYYGLPS-QGGGC 49
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1615-2118 |
9.38e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 61.67 E-value: 9.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1615 GKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQ-DLAIAIERLQM---SITEIMEKTTLNQtldEDfllpns 1690
Cdd:pfam15921 72 GKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSViDLQTKLQEMQMerdAMADIRRRESQSQ---ED------ 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1691 tLQNmqqngtslleimqirdftQLhQNATLELKAAEDLLSQIQENYQKPLEELEvlKEAASHvlskhnnelkaaealvre 1770
Cdd:pfam15921 143 -LRN------------------QL-QNTVHELEAAKCLKEDMLEDSNTQIEQLR--KMMLSH------------------ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1771 aEAKMQESNHLLLmvnaNLREFSDKKLHVQEE------QNLTSELIVQGRGL---IDAAAAQTDAVQDALEHLE-DHQDK 1840
Cdd:pfam15921 183 -EGVLQEIRSILV----DFEEASGKKIYEHDSmstmhfRSLGSAISKILRELdteISYLKGRIFPVEDQLEALKsESQNK 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1841 LLLWSAKIRHHIDDLVmhmsQRNAVDLVYRAEDhAAEFQRLADVLYSGLENIRNVSLNATSAAYVHY-NIQSLIEESEEL 1919
Cdd:pfam15921 258 IELLLQQHQDRIEQLI----SEHEVEITGLTEK-ASSARSQANSIQSQLEIIQEQARNQNSMYMRQLsDLESTVSQLRSE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1920 ARDAHRTVTET--SLLSESLVSNGKAAVQRSSR--FLKEGNNLSRKLPGI---------ALELSELRNKT--NRFQENAV 1984
Cdd:pfam15921 333 LREAKRMYEDKieELEKQLVLANSELTEARTERdqFSQESGNLDDQLQKLladlhkrekELSLEKEQNKRlwDRDTGNSI 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1985 EITR------QTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQ 2058
Cdd:pfam15921 413 TIDHlrreldDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE 492
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281185471 2059 DS--TMATLLAGRKVKDVEIQA------------NLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKV 2118
Cdd:pfam15921 493 SSerTVSDLTASLQEKERAIEAtnaeitklrsrvDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEI 566
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1089-1147 |
2.05e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.74 E-value: 2.05e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 1089 PCDCDLRGTSGDACNleqglcgcvEETGACPCKENVFGPQCNECREGTFALrADNPLGC 1147
Cdd:cd00055 1 PCDCNGHGSLSGQCD---------PGTGQCECKPNTTGRRCDRCAPGYYGL-PSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
791-846 |
2.39e-08 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 52.36 E-value: 2.39e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 281185471 791 CACPLTIASnnfSPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNPTVPGESC 846
Cdd:pfam00053 1 CDCNPHGSL---SDTCDPETG---QCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1593-1842 |
3.54e-08 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 59.08 E-value: 3.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1593 NLENTTKYLQESLlkENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIM 1672
Cdd:PRK04778 253 DIEKEIQDLKEQI--DENLALLEELDLDEAEEKNEEIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELK 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1673 EKTTLnqtLDEDFLLPNSTLQNMQQNGTSLLEIMqiRDFTQLHQNatleLKAAEDLLSQIQENYQKPLEELEVLKEaaSH 1752
Cdd:PRK04778 331 EEIDR---VKQSYTLNESELESVRQLEKQLESLE--KQYDEITER----IAEQEIAYSELQEELEEILKQLEEIEK--EQ 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1753 V-LSKHNNELKAAEALVREAEAKMQE--SNHLLLMVNANL----REFSDKKLHVQEE-QNLTSELiVQGRGLIDAAAAQT 1824
Cdd:PRK04778 400 EkLSEMLQGLRKDELEAREKLERYRNklHEIKRYLEKSNLpglpEDYLEMFFEVSDEiEALAEEL-EEKPINMEAVNRLL 478
|
250
....*....|....*...
gi 281185471 1825 DAVQDALEHLEDHQDKLL 1842
Cdd:PRK04778 479 EEATEDVETLEEETEELV 496
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1402-1440 |
6.32e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 51.20 E-value: 6.32e-08
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 281185471 1402 PCSCNNH---SDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYG 1440
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYG 41
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
270-317 |
1.34e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.43 E-value: 1.34e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 281185471 270 CICYGHAS---SCpwDETTkkLQCQCEHNTCGESCNRCCPGYHQQPWRPGT 317
Cdd:cd00055 2 CDCNGHGSlsgQC--DPGT--GQCECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1452-1506 |
1.58e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 50.04 E-value: 1.58e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 1452 CACPHSppASFSPTCVLEGdhdFRCDaCLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
Cdd:pfam00053 1 CDCNPH--GSLSDTCDPET---GQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
849-892 |
2.09e-07 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 49.62 E-value: 2.09e-07
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 281185471 849 CDCsgNVDPSEAGHCDSVTGECLkCLGNTDGAHCERCADGFYGD 892
Cdd:smart00180 1 CDC--DPGGSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1607-1828 |
3.07e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 55.61 E-value: 3.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1607 KENMQKDLGKI--KLEGVAEETDNLQKKLTRMlasTQKVNRATERIfKESQDlaiAIERLQmsiTEIMEkttLNQTLDED 1684
Cdd:COG3883 18 IQAKQKELSELqaELEAAQAELDALQAELEEL---NEEYNELQAEL-EALQA---EIDKLQ---AEIAE---AEAEIEER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1685 FLLPNSTLQNMQQNGTS---LLEIMQIRDFTQLHQNATLeLKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL 1761
Cdd:COG3883 85 REELGERARALYRSGGSvsyLDVLLGSESFSDFLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281185471 1762 KAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQ 1828
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1403-1441 |
1.02e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 47.69 E-value: 1.02e-06
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 281185471 1403 CSCN---NHSDTCDPNTGKCLnCGDNTAGDHCDVCTSGYYGK 1441
Cdd:smart00180 1 CDCDpggSASGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
742-783 |
1.21e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 47.31 E-value: 1.21e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 281185471 742 CECH--GHAAE-CN-VHGVCIaCAHNTTGVHCEQCLPGFYGEPSRG 783
Cdd:smart00180 1 CDCDpgGSASGtCDpDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1594-1935 |
1.41e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 54.34 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1594 LENTTKYL--QESLLKENMQkdlgkikLEGVAEETDNLQKKLTRMLASTQKvnraterifkESQDLAIaierlQMSITEI 1671
Cdd:pfam05483 407 LEELKKILaeDEKLLDEKKQ-------FEKIAEELKGKEQELIFLLQAREK----------EIHDLEI-----QLTAIKT 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1672 MEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAAS 1751
Cdd:pfam05483 465 SEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEM 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1752 HVL-----------------------SKHNNELKAAEALVREAEAKMQES--NHLLLMV---NANLREFSD-----KKLH 1798
Cdd:pfam05483 545 NLRdelesvreefiqkgdevkckldkSEENARSIEYEVLKKEKQMKILENkcNNLKKQIenkNKNIEELHQenkalKKKG 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1799 VQEEQNLTS-ELIVQGRGLIDAAAAQ-----TDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS------QRNAVD 1866
Cdd:pfam05483 625 SAENKQLNAyEIKVNKLELELASAKQkfeeiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKeidkrcQHKIAE 704
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1867 LVYRAEDHAAEFQRLAD---------------------VLYSGLENIRNVSLNatsaayVHYNIQSLIEESEELARDAHR 1925
Cdd:pfam05483 705 MVALMEKHKHQYDKIIEerdselglyknkeqeqssakaALEIELSNIKAELLS------LKKQLEIEKEEKEKLKMEAKE 778
|
410
....*....|
gi 281185471 1926 TvteTSLLSE 1935
Cdd:pfam05483 779 N---TAILKD 785
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1591-1855 |
2.48e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1591 LSNLENTTKYLQESLlkenmqkDLGKIKLEGVAEETDNLQKKL----TRMLASTQKVNRATE---RIFKESQDLAIAIER 1663
Cdd:TIGR02168 679 IEELEEKIEELEEKI-------AELEKALAELRKELEELEEELeqlrKELEELSRQISALRKdlaRLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1664 LQMSITEIM-EKTTLNQTLDEDFLLPNSTLQNMQQngtslLEiMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEE 1742
Cdd:TIGR02168 752 LSKELTELEaEIEELEERLEEAEEELAEAEAEIEE-----LE-AQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1743 LEVLK------------------------EAASHVLS-------KHNNELKAAEALVREAEAKMQESNHLLLMVNANLRE 1791
Cdd:TIGR02168 826 LESLErriaaterrledleeqieelsediESLAAEIEeleelieELESELEALLNERASLEEALALLRSELEELSEELRE 905
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 1792 FSDKKL-----------HVQEEQNLTSELIVQGRGLIDAAAAQtdaVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855
Cdd:TIGR02168 906 LESKRSelrreleelreKLAQLELRLEGLEVRIDNLQERLSEE---YSLTLEEAEALENKIEDDEEEARRRLKRL 977
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1728-2094 |
4.50e-06 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 51.83 E-value: 4.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1728 LLSQIQENYQKPLEELEVLKEAashvLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREfsdkklhVQEEQNLTS 1807
Cdd:COG4372 25 LIAALSEQLRKALFELDKLQEE----LEQLREELEQAREELEQLEEELEQARSELEQLEEELEE-------LNEQLQAAQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1808 ELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNavdlvyraedhaaefQRLADvLYS 1887
Cdd:COG4372 94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAERE---------------EELKE-LEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1888 GLENIRNvSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKL-PGIA 1966
Cdd:COG4372 158 QLESLQE-ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLgLALS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1967 LELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRV 2046
Cdd:COG4372 237 ALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDA 316
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 281185471 2047 NTTLRETHQL-LQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEEN 2094
Cdd:COG4372 317 LLAALLELAKkLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEA 365
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
790-844 |
5.47e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 45.81 E-value: 5.47e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 281185471 790 PCACPLTIASNnfsPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNPTVPGE 844
Cdd:cd00055 1 PCDCNGHGSLS---GQCDPGTG---QCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1607-2114 |
1.02e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1607 KENMQKDLG--KIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEImeKTTLNQTLDED 1684
Cdd:TIGR02169 338 IEELEREIEeeRKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL--KRELDRLQEEL 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1685 FLLpNSTLQNMQQNGTSLLEimQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHV---LSKHNNEL 1761
Cdd:TIGR02169 416 QRL-SEELADLNAAIAGIEA--KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQREL 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1762 KAAEALVREAEAKMQESNHLLLMVNANLRefsdkKLH--------VQEEQNLTSELIVQGRglIDAAAAQTDAV-QDALE 1832
Cdd:TIGR02169 493 AEAEAQARASEERVRGGRAVEEVLKASIQ-----GVHgtvaqlgsVGERYATAIEVAAGNR--LNNVVVEDDAVaKEAIE 565
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1833 HLEDHQ-------------DKLLLWSAKIRHHIDDLvmhmsqrnAVDLV-YRAEDHAAEFQRLAD-VLYSGLE------- 1890
Cdd:TIGR02169 566 LLKRRKagratflplnkmrDERRDLSILSEDGVIGF--------AVDLVeFDPKYEPAFKYVFGDtLVVEDIEaarrlmg 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1891 NIRNVSL---------------NATSAAYVHYniqslIEESEELARDAHRtVTETSLLSESLVSNGKAAVQRSSRFLKEG 1955
Cdd:TIGR02169 638 KYRMVTLegelfeksgamtggsRAPRGGILFS-----RSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLDELSQEL 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1956 NNLSRKLPGIALELSELRNKTNRFQENAVEITRQtneslliLRAIPKGIRDKGAKTKELAT--SASQSAVSTLRD-VAGL 2032
Cdd:TIGR02169 712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEED-------LSSLEQEIENVKSELKELEAriEELEEDLHKLEEaLNDL 784
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2033 SQELL-----NTSASLSRVNTT-------LRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS 2100
Cdd:TIGR02169 785 EARLShsripEIQAELSKLEEEvsriearLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864
|
570
....*....|....
gi 281185471 2101 EIKLLIsqARKQAA 2114
Cdd:TIGR02169 865 ELEEEL--EELEAA 876
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
706-1018 |
1.51e-05 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 50.35 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 706 VEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAH------NTTGvHCEQCLPGFYge 779
Cdd:pfam03302 25 TENCKACSNDKREVCEECNSNNYLTPTSQCIDDCAKIGNYYYTTNANNKKICKECTVancktcEDQG-QCQACNDGFY-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 780 psrgTPGD-CQPCACPLTIASNNFSPTC----------HLNDGDEVVC-DWCAPGYSGAWCERCAdgyygnPTVPGES-C 846
Cdd:pfam03302 102 ----KSGDaCSPCHESCKTCSGGTASDCtecltgkalrYGNDGTKGTCgEGCTTGTGAGACKTCG------LTIDGTSyC 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 847 VPCDCSGNVdpSEAGHCDSVTGECLKCLGNTDGAH--CERCADGFY-------------GDAV--TAKNCRACECHVKGS 909
Cdd:pfam03302 172 SECATETEY--PQNGVCTSTAARATATCKASSVANgmCSSCANGYFrmnggcyettkfpGKSVceEANSGGTCQKEAPGY 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 910 HSAVCHLETGLCDCKPNVTGQQCDQCLHGYygLDSGHGCRPCNCSVAgsvsdGCTDEGQchcvpgvagkRCDRCAHGFY- 988
Cdd:pfam03302 250 KLNNGDLVTCSPGCKTCTSNTVCTTCMDGY--VKTSDSCTKCDSSCE-----TCTGATT----------TCKTCATGYYk 312
|
330 340 350
....*....|....*....|....*....|.
gi 281185471 989 -AYQDGSCTPCDcphTQNTCDPETGECVCPP 1018
Cdd:pfam03302 313 sGTGCVSCTSSE---SDNGITGVKGCLNCAP 340
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1564-1828 |
2.33e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 50.60 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1564 LLNDLDEIGDavlslnlTGIIPVPYGILSNLENTT-KYLQESL--LKENMQKDLGKIKLEGVAEETDNLQKKLTRMLAST 1640
Cdd:PTZ00440 2334 LINDLDNYQD-------ENYGKDKNIELNNENNSYiIKTKEKInnLKEEFSKLLKNIKRNNTLCNNNNIKDFISNIGKSV 2406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1641 QKVNRATERIFKESQDLaIAIERLQMSITEIMEKTTLNQTLDEdflLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATL 1720
Cdd:PTZ00440 2407 ETIKQRFSSNLPEKEKL-HQIEENLNEIKNIMNETKRISNVDA---FTNKILQDIDNEKNKENNNMNAEKIDDLIENVTS 2482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1721 -------ELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFS 1793
Cdd:PTZ00440 2483 hnekiksELLIINDALRRVKEKKDEMNKLFNSLTENNNNNNNSAKNIVDNSTYIINELESHVSKLNELLSYIDNEIKELE 2562
|
250 260 270
....*....|....*....|....*....|....*
gi 281185471 1794 DKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQ 1828
Cdd:PTZ00440 2563 NEKLKLLEKAKIEESRKERERIESETQEDNTDEEQ 2597
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
791-839 |
2.48e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.84 E-value: 2.48e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 281185471 791 CACPLtiaSNNFSPTCHLNDGdevVCDwCAPGYSGAWCERCADGYYGNP 839
Cdd:smart00180 1 CDCDP---GGSASGTCDPDTG---QCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1618-1826 |
2.85e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 2.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1618 KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEI--------MEKTTLNQTLDEDFLLPN 1689
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeaelaeleKEIAELRAELEAQKEELA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1690 STLQNMQQNG--TSLLEIMQIRDFTQLHQNATLeLKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEAL 1767
Cdd:COG4942 108 ELLRALYRLGrqPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 281185471 1768 VREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDA 1826
Cdd:COG4942 187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1598-2016 |
3.24e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.06 E-value: 3.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1598 TKYLQ---ESLLK-ENMQKDLgkIKLEGVAEETDNLQKKLTRmlastQKvnRATERiFKESQDlaiAIERLQMSITeIME 1673
Cdd:TIGR02168 168 SKYKErrkETERKlERTRENL--DRLEDILNELERQLKSLER-----QA--EKAER-YKELKA---ELRELELALL-VLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1674 KTTLNQTLDEdfllpnstLQnmqqngtslleiMQIRDFTQLHQNATLELKAAEDLLSQI----------QENYQKPLEEL 1743
Cdd:TIGR02168 234 LEELREELEE--------LQ------------EELKEAEEELEELTAELQELEEKLEELrlevseleeeIEELQKELYAL 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1744 evlkeaashvlskhNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQ 1823
Cdd:TIGR02168 294 --------------ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1824 TDAVQDALEHLEDHQDKLllwsakiRHHIDdlvmhmSQRNAVDLVYRAEDhaaefqrladvlysglenirnvSLNATsaa 1903
Cdd:TIGR02168 360 LEELEAELEELESRLEEL-------EEQLE------TLRSKVAQLELQIA----------------------SLNNE--- 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1904 yvhynIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQrssrflkegnnlsRKLPGIALELSELRNKTNRFQENA 1983
Cdd:TIGR02168 402 -----IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ-------------AELEELEEELEELQEELERLEEAL 463
|
410 420 430
....*....|....*....|....*....|...
gi 281185471 1984 VEITRQTNESLLILRAIPKGIRDKGAKTKELAT 2016
Cdd:TIGR02168 464 EELREELEEAEQALDAAERELAQLQARLDSLER 496
|
|
| BAR |
smart00721 |
BAR domain; |
1609-1841 |
3.63e-05 |
|
BAR domain;
Pssm-ID: 214787 [Multi-domain] Cd Length: 239 Bit Score: 47.76 E-value: 3.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1609 NMQKDLGKIK---LE--GVAEET------DNLQKKLTRMLASTQKVNRATERiFKESQDLAIAIERLQMSITEIMEKTTL 1677
Cdd:smart00721 1 GFKKQFNRAKqkvGEkvGKAEKTkldedfEELERRFDTTEAEIEKLQKDTKL-YLQPNPAVRAKLASQKKLSKSLGEVYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1678 NQTLDEDFLLPNSTLQNMQQNGTSLLEIMQI-RDFTQLHQNATLEL-KAAEDLLSQIQENYQKpLEELEVLKEAASHVLS 1755
Cdd:smart00721 80 GGDDGEGLGADSSYGKALDKLGEALKKLLQVeESLSQVKRTFILPLlNFLLGEFKEIKKARKK-LERKLLDYDSARHKLK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1756 KH--------NNELKAAEALVREAEAKMQESNHLLLmvnANLREFSDKK--LHVQEEQNLtselivqgrglidaAAAQTD 1825
Cdd:smart00721 159 KAkkskekkkDEKLAKAEEELRKAKQEFEESNAQLV---EELPQLVASRvdFFVNCLQAL--------------IEAQLN 221
|
250
....*....|....*.
gi 281185471 1826 AVQDALEHLEDHQDKL 1841
Cdd:smart00721 222 FHRESYKLLQQLQQQL 237
|
|
| Laminin_G_3 |
pfam13385 |
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin ... |
2895-3024 |
6.19e-05 |
|
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.
Pssm-ID: 463865 [Multi-domain] Cd Length: 151 Bit Score: 45.84 E-value: 6.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2895 FDGSGYAALvkeGYKVQSDVNITLEF---RTSSQNGVLLGISTAKVDAIGLELV-DGKVLFHVNNGAGRITAAYEPKTAT 2970
Cdd:pfam13385 1 DGGSDYVTL---PDALLPTSDFTVSAwvkPDSLPGWARAIISSSGGGGYSLGLDgDGRLRFAVNGGNGGWDTVTSGASVP 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 281185471 2971 vlcDGKWHTLQANKSKHRITLIVDGNAVGaESPHTQSTSVDTNNPIYVGGYPAG 3024
Cdd:pfam13385 78 ---LGQWTHVAVTYDGGTLRLYVNGVLVG-SSTLTGGPPPGTGGPLYIGRSPGG 127
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
720-1047 |
6.94e-05 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 48.04 E-value: 6.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 720 CESCLSGYyrvdGILFGGICQPCechghAAECNVHGvCIACAHNTTGVhCEQCLPGFYGEPSRGTPGDCQPCAcpltias 799
Cdd:pfam03302 1 CDECKPGY----ELSADKTKCTS-----SAPCKTEN-CKACSNDKREV-CEECNSNNYLTPTSQCIDDCAKIG------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 800 nnfSPTCHLNDGDEVVCDWCAPGY-----SGAWCERCADGYYGNptvpGESCVPCD--CSGNVDPSEAGHCDSVTGECLK 872
Cdd:pfam03302 63 ---NYYYTTNANNKKICKECTVANcktceDQGQCQACNDGFYKS----GDACSPCHesCKTCSGGTASDCTECLTGKALR 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 873 cLGN--TDGAHCERCADGfygdaVTAKNCRACECHVKG-SHSAVCHLET-----GLCD---------CK-PNVTGQQCDQ 934
Cdd:pfam03302 136 -YGNdgTKGTCGEGCTTG-----TGAGACKTCGLTIDGtSYCSECATETeypqnGVCTstaaratatCKaSSVANGMCSS 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 935 CLHGYYGLDSG----------------HGCRPCNCSVAG-SVSDGCTDEGQCHCVPGVAGKRCDRCAHGfYAYQDGSCTP 997
Cdd:pfam03302 210 CANGYFRMNGGcyettkfpgksvceeaNSGGTCQKEAPGyKLNNGDLVTCSPGCKTCTSNTVCTTCMDG-YVKTSDSCTK 288
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 281185471 998 CDcphtqNTCDPETGecvcpphtQGVKCEECEDGHwgYDAEVGCQACNCS 1047
Cdd:pfam03302 289 CD-----SSCETCTG--------ATTTCKTCATGY--YKSGTGCVSCTSS 323
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
1763-2102 |
3.46e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 46.17 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1763 AAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLL 1842
Cdd:COG0840 28 ALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1843 LWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARD 1922
Cdd:COG0840 108 ALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAA 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1923 AHRTVTETSLLSESLVSNGKAAVQRSSRFLKE--GNNLSRKLP-GIALELSELRNKTNRFQENAVEITRQTNESLLILRA 1999
Cdd:COG0840 188 LLALVALAIILALLLSRSITRPLRELLEVLERiaEGDLTVRIDvDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVAS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2000 IPKGIRdkgAKTKELATSASQSAvSTLRDVAGLSQELlntSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQAN 2079
Cdd:COG0840 268 ASEELA---ASAEELAAGAEEQA-ASLEETAAAMEEL---SATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIE 340
|
330 340
....*....|....*....|....*..
gi 281185471 2080 LLFDRLKPL----KMLEENlSRNLSEI 2102
Cdd:COG0840 341 EIRESVEETaetiEELGES-SQEIGEI 366
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
289-313 |
3.81e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.37 E-value: 3.81e-04
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1595-2131 |
3.88e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1595 ENTTKYLQ-----ESLLKENmQKDLGKI---------KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIA 1660
Cdd:PRK03918 179 ERLEKFIKrteniEELIKEK-EKELEEVlreineissELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1661 IERLQMSITEIMEKTTLNQTLDEDFllpnSTLQNMQQNGTSLLEIMQIRD-FTQLHQNATLELKAAEDLLSQIQ------ 1733
Cdd:PRK03918 258 EEKIRELEERIEELKKEIEELEEKV----KELKELKEKAEEYIKLSEFYEeYLDELREIEKRLSRLEEEINGIEerikel 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1734 ENYQKPLEELEVLKEAashvLSKHNNELKAAEALVREAEAKMQESNHL--------LLMVNANLREFSDKKLHVQEE-QN 1804
Cdd:PRK03918 334 EEKEERLEELKKKLKE----LEKRLEELEERHELYEEAKAKKEELERLkkrltgltPEKLEKELEELEKAKEEIEEEiSK 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1805 LTSElivqgRGLIDAAAAQtdaVQDALEHLEDHQDKLLLWSAKI-RHHIDDLvmhMSQrnavdlvYRAE--DHAAEFQRL 1881
Cdd:PRK03918 410 ITAR-----IGELKKEIKE---LKKAIEELKKAKGKCPVCGRELtEEHRKEL---LEE-------YTAElkRIEKELKEI 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1882 ADVLYSGLENIRNVS--LNATSAAYVHYNIQSLIEE---------SEELARDA--HRTVTETSLLSESLVSNGKAAVQRS 1948
Cdd:PRK03918 472 EEKERKLRKELRELEkvLKKESELIKLKELAEQLKEleeklkkynLEELEKKAeeYEKLKEKLIKLKGEIKSLKKELEKL 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1949 SRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESL-------LILRAIPKGIRDKGAKTKELATSASQS 2021
Cdd:PRK03918 552 EELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELepfyneyLELKDAEKELEREEKELKKLEEELDKA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 2022 avstLRDVAGLSQELLNTSASLSRVNTTL-RETHQLLQDSTM--ATLLAGrkvKDVEIQAnlLFDRLKPLKMLEENLSRN 2098
Cdd:PRK03918 632 ----FEELAETEKRLEELRKELEELEKKYsEEEYEELREEYLelSRELAG---LRAELEE--LEKRREEIKKTLEKLKEE 702
|
570 580 590
....*....|....*....|....*....|....*.
gi 281185471 2099 LSEIKllisQARKQAASIKVA---VSADRDCIRAYQ 2131
Cdd:PRK03918 703 LEERE----KAKKELEKLEKAlerVEELREKVKKYK 734
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1703-1841 |
4.18e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 4.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1703 LEIMQIRdftqlHQNATL--ELKAAEDLLSQIQENYQKPLEELEVLKEAashvLSKHNNELKAAEALVREAEAKmqesnh 1780
Cdd:COG1579 17 SELDRLE-----HRLKELpaELAELEDELAALEARLEAAKTELEDLEKE----IKRLELEIEEVEARIKKYEEQ------ 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281185471 1781 llLMVNANLREFSD--KKLHVQE-EQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKL 1841
Cdd:COG1579 82 --LGNVRNNKEYEAlqKEIESLKrRISDLEDEILELMERIEELEEELAELEAELAELEAELEEK 143
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
816-1112 |
1.06e-03 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 44.19 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 816 CDWCAPGYSGAwCERCADGYYGNPTvpgESCVP-CDCSGNVDPSEAGHCDSVTGECL--KCLGNTDGAHCERCADGFY-- 890
Cdd:pfam03302 28 CKACSNDKREV-CEECNSNNYLTPT---SQCIDdCAKIGNYYYTTNANNKKICKECTvaNCKTCEDQGQCQACNDGFYks 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 891 GDAVTA--KNCRAC---------EChVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSV---A 956
Cdd:pfam03302 104 GDACSPchESCKTCsggtasdctEC-LTGKALRYGNDGTKGTCGEGCTTGTGAGACKTCGLTIDGTSYCSECATETeypQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 957 GSVSDGCTDEGQCHCVPG-VAGKRCDRCAHGFYAyQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEE-----CED 1030
Cdd:pfam03302 183 NGVCTSTAARATATCKASsVANGMCSSCANGYFR-MNGGCYETTKFPGKSVCEEANSGGTCQKEAPGYKLNNgdlvtCSP 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1031 GHWGYDAEVGCQAC---------NCSLVGSThhrCDVVTGHCQckskfggrACDQCSLG-YRDFPDCVPCdcdlrgTSGD 1100
Cdd:pfam03302 262 GCKTCTSNTVCTTCmdgyvktsdSCTKCDSS---CETCTGATT--------TCKTCATGyYKSGTGCVSC------TSSE 324
|
330
....*....|..
gi 281185471 1101 ACNLEQGLCGCV 1112
Cdd:pfam03302 325 SDNGITGVKGCL 336
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1452-1507 |
1.07e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 39.26 E-value: 1.07e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 281185471 1452 CACPhsPPASFSPTCVlegDHDFRCDaCLLGYEGKHCERCSSSYYGNPQTPGGsCQ 1507
Cdd:cd00055 2 CDCN--GHGSLSGQCD---PGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG-CQ 50
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1641-2010 |
1.40e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1641 QKVNRATERIFKESQDLAIAIERLQMSITEIMEKttlnqtldedfllpnstLQNMQQngtslleimQIRDFTQLHQNATL 1720
Cdd:COG4372 6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFE-----------------LDKLQE---------ELEQLREELEQARE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1721 ELKAAEDLLSQIQENYQKPLEELEVLKE---AASHVLSKHNNELKAAEALVREAEAKMQEsnhlllmVNANLREFSDKKL 1797
Cdd:COG4372 60 ELEQLEEELEQARSELEQLEEELEELNEqlqAAQAELAQAQEELESLQEEAEELQEELEE-------LQKERQDLEQQRK 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1798 HVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEdhQDKLLLWSAKIRHHIDDLVMHmSQRNAVDLVYRAEDHAAE 1877
Cdd:COG4372 133 QLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE--QELQALSEAEAEQALDELLKE-ANRNAEKEEELAEAEKLI 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 1878 FQrLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL--------SESLVSNGKAAVQRSS 1949
Cdd:COG4372 210 ES-LPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELElailvekdTEEEELEIAALELEAL 288
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281185471 1950 RFLKEGNNLSRKLPGIALELSELRNKTNrFQENAVEITRQTNESLLILRAIPKGIRDKGAK 2010
Cdd:COG4372 289 EEAALELKLLALLLNLAALSLIGALEDA-LLAALLELAKKLELALAILLAELADLLQLLLV 348
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
270-316 |
2.75e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.10 E-value: 2.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 281185471 270 CICYGHAS---SCpwDETTkkLQCQCEHNTCGESCNRCCPGYHQQPWRPG 316
Cdd:pfam00053 1 CDCNPHGSlsdTC--DPET--GQCLCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| TNFRSF4 |
cd13406 |
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; ... |
872-957 |
6.14e-03 |
|
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; TNFRSF4 (also known as OX40, ACT35, CD134, IMD16, TXGP1L) activates NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. It also promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. It is primarily expressed on activated CD4+ and CD8+ T cells, where it is transiently expressed and upregulated on the most recently antigen-activated T cells within inflammatory lesions. This makes it an attractive target to modulate immune responses, i.e. TNFRSF4 (OX40) blocking agents to inhibit adverse inflammation or agonists to enhance immune responses. An artificially created biologic fusion protein, OX40-immunoglobulin (OX40-Ig), prevents OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Some single nucleotide polymorphisms (SNPs) of its natural ligand OX40 ligand (OX40L, CD252), which is also found on activated T cells, have been associated with systemic lupus erythematosus.
Pssm-ID: 276911 [Multi-domain] Cd Length: 142 Bit Score: 39.69 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 872 KCLGNTDgAHCERCADGFYGDAVTAKNCRAC-EC-HVKGSH--SAVCHLETGLCDCKPNVT-------GQQCDQCLHGYY 940
Cdd:cd13406 27 RCTGTQD-TVCSPCEPGFYNEAVNYEPCKPCtQCnQRSGSEekQKCTKTSDTVCRCRPGTQpldsykpGVDCVPCPPGHF 105
|
90
....*....|....*...
gi 281185471 941 GLDSGHGCRP-CNCSVAG 957
Cdd:cd13406 106 SRGDNQACKPwTNCSLAG 123
|
|
| TNFRSF4 |
cd13406 |
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; ... |
979-1052 |
6.19e-03 |
|
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134 or OXO40; TNFRSF4 (also known as OX40, ACT35, CD134, IMD16, TXGP1L) activates NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. It also promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. It is primarily expressed on activated CD4+ and CD8+ T cells, where it is transiently expressed and upregulated on the most recently antigen-activated T cells within inflammatory lesions. This makes it an attractive target to modulate immune responses, i.e. TNFRSF4 (OX40) blocking agents to inhibit adverse inflammation or agonists to enhance immune responses. An artificially created biologic fusion protein, OX40-immunoglobulin (OX40-Ig), prevents OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Some single nucleotide polymorphisms (SNPs) of its natural ligand OX40 ligand (OX40L, CD252), which is also found on activated T cells, have been associated with systemic lupus erythematosus.
Pssm-ID: 276911 [Multi-domain] Cd Length: 142 Bit Score: 39.69 E-value: 6.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281185471 979 RCDRCAHGFYA-----YQDGSCTPCD---CPHTQNTCDPETGE-CVCPPHTQ-------GVKCEECEDGHWgydAEVGCQ 1042
Cdd:cd13406 35 VCSPCEPGFYNeavnyEPCKPCTQCNqrsGSEEKQKCTKTSDTvCRCRPGTQpldsykpGVDCVPCPPGHF---SRGDNQ 111
|
90
....*....|....
gi 281185471 1043 AC----NCSLVGST 1052
Cdd:cd13406 112 ACkpwtNCSLAGKR 125
|
|
| |
