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Conserved domains on  [gi|46576685|sp|P60986|]
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RecName: Full=Prolactin-inducible protein homolog; AltName: Full=Prolactin-induced protein; Flags: Precursor

Protein Classification

SVA domain-containing protein( domain architecture ID 10526373)

SVA domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SVA pfam05326
Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and ...
 3-127 5.46e-55

Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and prolactin-inducible (PIP) proteins. Seminal vesicle autoantigen (SVA) is specifically present in the seminal plasma of mice. This 19-kDa secretory glycoprotein suppresses the motility of spermatozoa by interacting with phospholipid. PIP, has several known functions. In saliva, this protein plays a role in host defence by binding to microorganizms such as Streptococcus. PIP is an aspartyl proteinase and it acts as a factor capable of suppressing T-cell apoptosis through its interaction with CD4.


:

Pssm-ID: 398804  Cd Length: 124  Bit Score: 168.35  E-value: 5.46e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46576685     3 SLHLLLRASPAALLLILCLQLGTTKAQEDTtsRQLMTMDLQMLQI-DTSEEATVVLEVSTDLRECMVVKAYLLSNIPIEG 81
Cdd:pfam05326   1 SLQLLFQPSAATLLLILCLQLETAKGQDNR--NKPLSLDLKVPSTaKKNNEVTVTLTVKTNVKECMVVKAYLESNPPIKG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 46576685    82 NFNYKFTSCLCNNYPRRFFWDLQTNSTVRITAVVDVIRELGICPDD 127
Cdd:pfam05326  79 SFNYIYTACLCNDYPRTFFWDIQVNRTVTLAAVVDIVREKNICPDD 124
 
Name Accession Description Interval E-value
SVA pfam05326
Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and ...
 3-127 5.46e-55

Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and prolactin-inducible (PIP) proteins. Seminal vesicle autoantigen (SVA) is specifically present in the seminal plasma of mice. This 19-kDa secretory glycoprotein suppresses the motility of spermatozoa by interacting with phospholipid. PIP, has several known functions. In saliva, this protein plays a role in host defence by binding to microorganizms such as Streptococcus. PIP is an aspartyl proteinase and it acts as a factor capable of suppressing T-cell apoptosis through its interaction with CD4.


Pssm-ID: 398804  Cd Length: 124  Bit Score: 168.35  E-value: 5.46e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46576685     3 SLHLLLRASPAALLLILCLQLGTTKAQEDTtsRQLMTMDLQMLQI-DTSEEATVVLEVSTDLRECMVVKAYLLSNIPIEG 81
Cdd:pfam05326   1 SLQLLFQPSAATLLLILCLQLETAKGQDNR--NKPLSLDLKVPSTaKKNNEVTVTLTVKTNVKECMVVKAYLESNPPIKG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 46576685    82 NFNYKFTSCLCNNYPRRFFWDLQTNSTVRITAVVDVIRELGICPDD 127
Cdd:pfam05326  79 SFNYIYTACLCNDYPRTFFWDIQVNRTVTLAAVVDIVREKNICPDD 124
 
Name Accession Description Interval E-value
SVA pfam05326
Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and ...
 3-127 5.46e-55

Seminal vesicle autoantigen (SVA); This family consists of seminal vesicle autoantigen and prolactin-inducible (PIP) proteins. Seminal vesicle autoantigen (SVA) is specifically present in the seminal plasma of mice. This 19-kDa secretory glycoprotein suppresses the motility of spermatozoa by interacting with phospholipid. PIP, has several known functions. In saliva, this protein plays a role in host defence by binding to microorganizms such as Streptococcus. PIP is an aspartyl proteinase and it acts as a factor capable of suppressing T-cell apoptosis through its interaction with CD4.


Pssm-ID: 398804  Cd Length: 124  Bit Score: 168.35  E-value: 5.46e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46576685     3 SLHLLLRASPAALLLILCLQLGTTKAQEDTtsRQLMTMDLQMLQI-DTSEEATVVLEVSTDLRECMVVKAYLLSNIPIEG 81
Cdd:pfam05326   1 SLQLLFQPSAATLLLILCLQLETAKGQDNR--NKPLSLDLKVPSTaKKNNEVTVTLTVKTNVKECMVVKAYLESNPPIKG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 46576685    82 NFNYKFTSCLCNNYPRRFFWDLQTNSTVRITAVVDVIRELGICPDD 127
Cdd:pfam05326  79 SFNYIYTACLCNDYPRTFFWDIQVNRTVTLAAVVDIVREKNICPDD 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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