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Conserved domains on  [gi|1332439622|gb|PNO36509|]
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single-stranded DNA-binding protein [Salmonella enterica subsp. houtenae serovar 50:g,z51:-]

Protein Classification

single-stranded DNA-binding protein( domain architecture ID 10793128)

single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 1-159 3.79e-94

single-stranded DNA-binding protein; Provisional


:

Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 270.18  E-value: 3.79e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80
Cdd:PRK09010    1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  81 EGQLRTRKWTDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGN--------------QPQAGQQFSG---QPQATGTA 143
Cdd:PRK09010   81 EGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGniggqqqggwgqpqQPQGGNQFSGgaqSRPQQSAP 160

                         170
                  ....*....|....*..
gi 1332439622 144 AAAGNEPP-PFDDDIPF 159
Cdd:PRK09010  161 AAPSNEPPmDFDDDIPF 177
 
Name Accession Description Interval E-value
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 1-159 3.79e-94

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 270.18  E-value: 3.79e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80
Cdd:PRK09010    1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  81 EGQLRTRKWTDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGN--------------QPQAGQQFSG---QPQATGTA 143
Cdd:PRK09010   81 EGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGniggqqqggwgqpqQPQGGNQFSGgaqSRPQQSAP 160

                         170
                  ....*....|....*..
gi 1332439622 144 AAAGNEPP-PFDDDIPF 159
Cdd:PRK09010  161 AAPSNEPPmDFDDDIPF 177
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 3-159 4.42e-71

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 211.12  E-value: 4.42e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   3 SRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQtGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEG 82
Cdd:TIGR00621   1 MRMVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQD-GEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  83 QLRTRKWTDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGNQPQAGQQFSGQPQATGTAAAAGNEPPP--------FD 154
Cdd:TIGR00621  80 RLRTRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQGGEFSGGGGSGNRPQGGQEQSATGKDPAQSAPQSgsadpidgDD 159


                  ....*
gi 1332439622 155 DDIPF 159
Cdd:TIGR00621 160 DEIPF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
6-123 2.25e-60

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 182.35  E-value: 2.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:COG0629     1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKD-QDGEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLR 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQP 123
Cdd:COG0629    80 TRSWEDKDGQKRYTTEVVAD---EIQFLGSRPSGGGGG 114
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 6-113 1.52e-49

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 154.70  E-value: 1.52e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGEGD--EETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQ 78

                          90       100
                  ....*....|....*....|....*...
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQML 113
Cdd:pfam00436  79 TRKYEDQEGQKRYVTEIVAD---EVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 9-105 2.39e-44

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 141.21  E-value: 2.39e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   9 VILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKqtGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRK 88
Cdd:cd04496     1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDR--DEEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRS 78

                          90
                  ....*....|....*..
gi 1332439622  89 WTDQAGVEKYTTEVVVN 105
Cdd:cd04496    79 WEDKDGQKRYGTEVVAD 95
 
Name Accession Description Interval E-value
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 1-159 3.79e-94

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 270.18  E-value: 3.79e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80
Cdd:PRK09010    1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  81 EGQLRTRKWTDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGN--------------QPQAGQQFSG---QPQATGTA 143
Cdd:PRK09010   81 EGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGniggqqqggwgqpqQPQGGNQFSGgaqSRPQQSAP 160

                         170
                  ....*....|....*..
gi 1332439622 144 AAAGNEPP-PFDDDIPF 159
Cdd:PRK09010  161 AAPSNEPPmDFDDDIPF 177
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 1-159 5.44e-77

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 226.54  E-value: 5.44e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   1 MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80
Cdd:PRK13732    1 MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDKQTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  81 EGQLRTRKWTDQaGVEKYTTEVVVNVGGTMQMLGGRPQNASqpgnQPQAGQQFSGQPQATGTA------------AAAGN 148
Cdd:PRK13732   81 EGQLRTRSWEDN-GITRYVTEILVKTTGTMQMLGRAPQQNA----QPQPGPQQNGQPQSADATkkggaktkgrgrKAAQP 155

                         170       180
                  ....*....|....*....|
gi 1332439622 149 EPPP---------FDDDIPF 159
Cdd:PRK13732  156 EPQPqppegedygFSDDIPF 175
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 3-159 1.62e-76

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 225.19  E-value: 1.62e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   3 SRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEG 82
Cdd:PRK05733    2 ARGVNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDKQSGQKVERTEWHRVSLFGKVAEIAGEYLRKGSQVYIEG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  83 QLRTRKWtDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGN-----------QPQAGQQFSGQPQATGTAAAAGNEPP 151
Cdd:PRK05733   82 KLQTREW-EKDGIKRYTTEIVVDMQGTMQLLGGRPQGDDQGGQgggnynqsaprQQAQRPQQAAQQQSRPAPQQPAPQPA 160

                         170
                  ....*....|..
gi 1332439622 152 P----FDDDIPF 159
Cdd:PRK05733  161 AdfdsFDDDIPF 172
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 3-159 4.42e-71

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 211.12  E-value: 4.42e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   3 SRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQtGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEG 82
Cdd:TIGR00621   1 MRMVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQD-GEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  83 QLRTRKWTDQAGVEKYTTEVVVNVGGTMQMLGGRPQNASQPGNQPQAGQQFSGQPQATGTAAAAGNEPPP--------FD 154
Cdd:TIGR00621  80 RLRTRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQGGEFSGGGGSGNRPQGGQEQSATGKDPAQSAPQSgsadpidgDD 159


                  ....*
gi 1332439622 155 DDIPF 159
Cdd:TIGR00621 160 DEIPF 164
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 5-159 1.08e-66

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 200.19  E-value: 1.08e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   5 GVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQL 84
Cdd:PRK06863    3 GINKVIIVGHLGNDPEIRTMPNGEAVANISVATSESWTDKNTGERREVTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  85 RTRKWTDQAGVEKYTTEVvvnVGGTMQMLGGRPQ-NASQPGNQPQAGQQFSGQPQATGTAAAAGNEPPP----------- 152
Cdd:PRK06863   83 KTRKWQDQNGQDRYTTEI---QGDVLQMLGGRNQrNAGGYGNSGPAPQQSYQAGQTNNGNSQQASRPAPqqaapqaeppm 159


                  ....*....
gi 1332439622 153 --FDDDIPF 159
Cdd:PRK06863  160 dgFDDDIPF 168
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
6-123 2.25e-60

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 182.35  E-value: 2.25e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:COG0629     1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKD-QDGEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLR 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQP 123
Cdd:COG0629    80 TRSWEDKDGQKRYTTEVVAD---EIQFLGSRPSGGGGG 114
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 1-159 1.33e-58

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 180.38  E-value: 1.33e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   1 MASrgVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYI 80
Cdd:PRK06958    1 MAS--VNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKASGEFKEATEWHRVAFFGRLAEIVGEYLKKGSSVYI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  81 EGQLRTRKWTDQAGVEKYTTEVVVNvggTMQMLGGR-------------------PQNASQPGNQPQA---GQQFSGQPQ 138
Cdd:PRK06958   79 EGRIRTRKWQGQDGQDRYSTEIVAD---QMQMLGGRggsgggggggdeggyggggGGGGGGYGGESRSgggGGRASGGGG 155

                         170       180
                  ....*....|....*....|....*..
gi 1332439622 139 ATGTAAAAGNEPPP------FDDDIPF 159
Cdd:PRK06958  156 GGAGGGASRPSAPAgggfdeMDDDIPF 182
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 6-159 3.83e-54

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 168.44  E-value: 3.83e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGK-LAEVAGEYLRKGSQVYIEGQL 84
Cdd:PRK06341    5 VNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNSGERKEKTEWHRVVIFNEgLCKVAEQYLKKGAKVYIEGQL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  85 RTRKWTDQAGVEKYTTEVVV-NVGGTMQMLGGRPQN--ASQPGNQPQAGQQFSGQPQATGTAAAAGNEPPPF----DDDI 157
Cdd:PRK06341   85 QTRKWTDQSGVERYSTEVVLqGFNSTLTMLDGRGEGggGGGGGDDGGGGDFGSSGPSRGGPRPASSGGGGNFsrdmDDDI 164


                  ..
gi 1332439622 158 PF 159
Cdd:PRK06341  165 PF 166
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 3-159 3.22e-50

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 158.56  E-value: 3.22e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   3 SRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQtGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEG 82
Cdd:PRK08763    2 ARGINKVILVGNLGNDPDIKYTQSGMTITRISLATTSVRKDRE-GNTQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  83 QLRTRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNAS------QPGNQPQAGQQFSGQPQATGTAAAAGNEPPPF--- 153
Cdd:PRK08763   81 SIRYDKFTGQDGQERYVTEIVAD---EMQMLGGRGEGGGgggggiRPQRQPAPRQNNGQDYAPRRQQPAPQQSAPPMddf 157


                  ....*..
gi 1332439622 154 -DDDIPF 159
Cdd:PRK08763  158 aDDDIPF 164
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 6-113 1.52e-49

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 154.70  E-value: 1.52e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGEGD--EETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQ 78

                          90       100
                  ....*....|....*....|....*...
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQML 113
Cdd:pfam00436  79 TRKYEDQEGQKRYVTEIVAD---EVQFL 103
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 6-159 2.53e-45

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 145.63  E-value: 2.53e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKEQTEWHRVVLFGK-LAEVAGEYLRKGSQVYIEGQL 84
Cdd:PRK06642    5 LNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDRITSERKERTEWHRVVIFSEgLVSVVERYVTKGSKLYIEGSL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1332439622  85 RTRKWTDQAGVEKYTTEVVV-NVGGTMQMLGGRPQNASqpgnqpqagQQFSGQPQATGTAAAAGN-EPPPFDDDIPF 159
Cdd:PRK06642   85 QTRKWNDNSGQEKYTTEVVLqNFNSQLILLDSKNSNNH---------NQDSGHSEYKHPETKNHSfDHSDLDDEIPF 152
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 9-105 2.39e-44

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 141.21  E-value: 2.39e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   9 VILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKqtGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRK 88
Cdd:cd04496     1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDR--DEEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRS 78

                          90
                  ....*....|....*..
gi 1332439622  89 WTDQAGVEKYTTEVVVN 105
Cdd:cd04496    79 WEDKDGQKRYGTEVVAD 95
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 7-159 9.23e-37

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 124.57  E-value: 9.23e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   7 NKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRdKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRT 86
Cdd:PRK08486    3 NKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFK-KQDGEKGEEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLTF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  87 RKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQPG--------------NQPQAGQQFSG-------QPQATGTAAA 145
Cdd:PRK08486   82 ESWMDQNGQKRSKHTITAE---SMQMLDSKSDNPQANAmqdnsfhenfnnnyPGNYNNPSQDPymnqaqsYNQNAYAKEN 158

                         170       180
                  ....*....|....*....|....
gi 1332439622 146 AGNEPPPF----------DDDIPF 159
Cdd:PRK08486  159 QQAQPPKYensvpeididEEEIPF 182
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 5-125 3.29e-22

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 85.51  E-value: 3.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   5 GVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkqtgemkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQL 84
Cdd:PRK07459    2 SLNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNRRSRD-------DEPDWFNLEIWGKTAQVAADYVKKGSLIGITGSL 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1332439622  85 RTRKWTD-QAGVEKYTTEVVVNvggTMQMLGGR--PQNASQPGN 125
Cdd:PRK07459   75 KFDRWTDrNTGEDRSKPVIRVD---RLELLGSKrdSEGNANPSN 115
PRK07274 PRK07274
single-stranded DNA-binding protein; Provisional
 7-125 2.32e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180914  Cd Length: 131  Bit Score: 81.34  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   7 NKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRT 86
Cdd:PRK07274    3 NKVILIGRLTATPELVKTANDKSVARVTLAVNRRFKN-QNGE--READFINVVLWGKLAETLASYASKGSLISIDGELRT 79

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1332439622  87 RKWtDQAGVEKYTTEVvvnVGGTMQMLGGRPQNASQPGN 125
Cdd:PRK07274   80 RKY-EKDGQTHYVTEV---LCQSFQLLESRAQRAMRENN 114
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 6-136 1.99e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 77.53  E-value: 1.99e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQtGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:PRK06751    2 MNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQ-GE--READFINCVIWRKQAENVANYLKKGSLAGVDGRLQ 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQPG--NQPQAGQQFSGQ 136
Cdd:PRK06751   79 TRNYEGQDGKRVYVTEVLAE---SVQFLEPRNGGGEQRGsfNQQPSGAGFGNQ 128
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 6-159 1.50e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 74.92  E-value: 1.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:PRK07275    2 INNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKS-QNGE--READFINCVIWRQQAENLANWAKKGALIGVTGRIQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQPGNQPQAG-QQFSGQPQATGTAAAAGN---EPPPF-------- 153
Cdd:PRK07275   79 TRNYENQQGQRVYVTEVVAD---NFQMLESRATREGGSGGSYNGGfNNAPSANSYSAPAQQTPNfgrDESPFgnsnpmdi 155


                  ....*..
gi 1332439622 154 -DDDIPF 159
Cdd:PRK07275  156 sDDDLPF 162
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 6-122 2.66e-16

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 70.06  E-value: 2.66e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEmkEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
Cdd:PRK06752    2 MNRVVLIGRLTKEPELYYTKQGVAYARVCVAVNRGFRN-SLGE--QQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIH 78

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1332439622  86 TRKWTDQAGVEKYTTEVVVNvggTMQMLGGRPQNASQ 122
Cdd:PRK06752   79 TRNYEDDQGKRIYITEVVIE---SITFLERRREGASQ 112
PRK07772 PRK07772
single-stranded DNA-binding protein; Provisional
 11-136 2.79e-14

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236092 [Multi-domain]  Cd Length: 186  Bit Score: 66.60  E-value: 2.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  11 LVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQTGEMKE-QTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRKW 89
Cdd:PRK07772    9 VVGNLTADPELRFTPSGAAVANFTVASTPRTFDRQTNEWKDgEALFLRCSIWRQAAENVAESLTKGMRVIVTGRLKQRSY 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1332439622  90 TDQAGVEKYTTEVVVN-VGGTMQMLGGRPQNASQPGNQPQAGQQFSGQ 136
Cdd:PRK07772   89 ETREGEKRTVVELEVDeIGPSLRYATAKVTRASRGGGGGGGGGGFGGG 136
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
 9-134 3.30e-12

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 60.69  E-value: 3.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622   9 VILVGNLGQDPEVRYMPNGGAVANITLATseswrdKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRK 88
Cdd:PRK06293    4 GYIVGRLGADPEERMTSKGKRVVVLRLGV------KSRVGSKDETVWCRCNIWGNRYDKMLPYLKKGSGVIVAGEMSPES 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1332439622  89 WTDQAGVEKYTTEVVVNvggTMQMLG-GRPQNASQPGNQPQAGQQFS 134
Cdd:PRK06293   78 YVDKDGSPQSSLVVSVD---TIKFSPfGRNEGSRQPSAGEDEGQQRG 121
PRK08182 PRK08182
single-stranded DNA-binding protein; Provisional
 13-137 2.44e-05

single-stranded DNA-binding protein; Provisional


Pssm-ID: 169261  Cd Length: 148  Bit Score: 41.98  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1332439622  13 GNLGQDPEVRYMPNGG----AVANITLATSESWRDKQtGEMKEQTE-WHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTR 87
Cdd:PRK08182    9 GNIGSAPEYREFPNGNdeprRLLRLNVYFDNPVPTKD-GEYEDRGGfWAPVELWHRDAEHWARLYQKGMRVLVEGRMERD 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1332439622  88 KWTDQAGVEKYTTEVVVNVGGTMQ------MLGGRPQNASQPGNQPQAGQQFSGQP 137
Cdd:PRK08182   88 EWTDNEDNERVTFKVEARRVGILPyriesvTLSPKPAATEPEAEPKPQAAQESTAP 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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