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Conserved domains on  [gi|1391641313|gb|PWN51854|]
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hypothetical protein IE53DRAFT_385779 [Violaceomyces palustris]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Prefoldin_UXT cd23158
protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in ...
 42-170 1.90e-29

protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in the cytoplasmic assembly of RNA polymerase I and can interact with other chaperone complexes, like R2TP, to form the PAQosome. UXT has an important role in the activation of the NF-kappaB pathway. UXT is also a component of the centrosome and is associated with gamma-tubulin. Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits being evolutionarily related.


:

Pssm-ID: 467474  Cd Length: 128  Bit Score: 105.27  E-value: 1.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391641313  42 RKFLVDRLLPDLETAQRRLDSIATEIQELEKLRVALRELDLQSDKEGVKdglYLSDLGEGVALQAGFSNQADPIISIGRG 121
Cdd:cd23158     2 EAFLNEVLKPDLKKVLEERDKLYEEISEYEQLKNTIETLQENDGLKPLK---TLVDLGCNFYVQAKVPDTSKIFVDVGLG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1391641313 122 NFLQLTNKEARAFISSKLKILERRKEAAYEKVAQIEAHVHLTSTSISQL 170
Cdd:cd23158    79 FYVEMTLDEALKFIDKKEKLLEKKADKLTKKAAKIKAHIKLVLEAIREL 127
 
Name Accession Description Interval E-value
Prefoldin_UXT cd23158
protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in ...
 42-170 1.90e-29

protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in the cytoplasmic assembly of RNA polymerase I and can interact with other chaperone complexes, like R2TP, to form the PAQosome. UXT has an important role in the activation of the NF-kappaB pathway. UXT is also a component of the centrosome and is associated with gamma-tubulin. Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits being evolutionarily related.


Pssm-ID: 467474  Cd Length: 128  Bit Score: 105.27  E-value: 1.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391641313  42 RKFLVDRLLPDLETAQRRLDSIATEIQELEKLRVALRELDLQSDKEGVKdglYLSDLGEGVALQAGFSNQADPIISIGRG 121
Cdd:cd23158     2 EAFLNEVLKPDLKKVLEERDKLYEEISEYEQLKNTIETLQENDGLKPLK---TLVDLGCNFYVQAKVPDTSKIFVDVGLG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1391641313 122 NFLQLTNKEARAFISSKLKILERRKEAAYEKVAQIEAHVHLTSTSISQL 170
Cdd:cd23158    79 FYVEMTLDEALKFIDKKEKLLEKKADKLTKKAAKIKAHIKLVLEAIREL 127
 
Name Accession Description Interval E-value
Prefoldin_UXT cd23158
protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in ...
 42-170 1.90e-29

protein UXT; UXT is an alpha subunit of the prefoldin-like complex (PFDL). PFDL is involved in the cytoplasmic assembly of RNA polymerase I and can interact with other chaperone complexes, like R2TP, to form the PAQosome. UXT has an important role in the activation of the NF-kappaB pathway. UXT is also a component of the centrosome and is associated with gamma-tubulin. Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits being evolutionarily related.


Pssm-ID: 467474  Cd Length: 128  Bit Score: 105.27  E-value: 1.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391641313  42 RKFLVDRLLPDLETAQRRLDSIATEIQELEKLRVALRELDLQSDKEGVKdglYLSDLGEGVALQAGFSNQADPIISIGRG 121
Cdd:cd23158     2 EAFLNEVLKPDLKKVLEERDKLYEEISEYEQLKNTIETLQENDGLKPLK---TLVDLGCNFYVQAKVPDTSKIFVDVGLG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1391641313 122 NFLQLTNKEARAFISSKLKILERRKEAAYEKVAQIEAHVHLTSTSISQL 170
Cdd:cd23158    79 FYVEMTLDEALKFIDKKEKLLEKKADKLTKKAAKIKAHIKLVLEAIREL 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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