|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
34-978 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 884.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 34 GAAVRDAFLSFFRDRhGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVVNSQKCVRAGGRHNDL 113
Cdd:PLN02900 13 GDRIRRTFLSFFESK-GHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 114 EDVGRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtGLDPDLETRDIWLSLgVPAS 193
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFG-DYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDE--KQAPDDEARAIWLDY-LPEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 194 RVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGSPQLV--------ELWNLVFMQHYREADGSLQLLPQRHVDTGMGL 265
Cdd:PLN02900 168 RVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVnnddprfiEIWNLVFIQFNREADGSLKPLPAKHVDTGMGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 266 ERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSGRVGAADEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLVL 345
Cdd:PLN02900 248 ERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 346 RRILRRAVRYSTEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLGPSD 425
Cdd:PLN02900 328 RRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 426 --LFPAEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQlAQKEAQHRAQQAEADQED-RLCLDVHALEELHRQGI 502
Cdd:PLN02900 408 gpVLSGKDAFLLYDT--YGFPVDLTELMAEERGVTVDMEGFEA-AMEEARERSRAAHLKAGGgAIELAAEATSWLQKQGV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 503 PTTDDSPKYNYTLHPngdyefglcEARVLQLYSETGtAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLvrTGQQDML 582
Cdd:PLN02900 485 AATDDFLKYDWLSDH---------EAVVKAILTGGG-FVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVL--EGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 583 FPVAGAQLCGGFILHEAMAPE-RLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFDV 661
Cdd:PLN02900 553 VEVSDVQKAGGFVLHIGTVTEgSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDF 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 662 ATQTLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLRSL-DEVYPDPVRVVsvgvpvahALGPasqaamHTS 740
Cdd:PLN02900 633 SHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVfGEKYPDPVRVV--------SVGG------VYS 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 741 VELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGEQAQQAREVGQSLSQEVEAASErlsqgsrdlPEAHRLSKDIG 820
Cdd:PLN02900 699 MELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALK---------VEGSDLEKKVA 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 821 RLTEVAESAVIPQWQRQELQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSEgplIVDTVSAESLSVLV-------- 892
Cdd:PLN02900 770 SLKSRVDAAVIPAAKKEEIRARVSALQKE----LRAAQKEAAALRAKLAVAKATE---LASKALSAGKSVLVarldvgvd 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 893 -----KVVRQLCKQAPSISVLLLSPQP-TGSVLCACQVAQDATPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTGHTAD- 964
Cdd:PLN02900 843 aaalkEAAEKVIAKLGDPAAVVLSSDEeKGKVSLVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEk 922
|
970
....*....|....
gi 115502845 965 LEAALGTARAYALS 978
Cdd:PLN02900 923 LDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
34-980 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 754.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 34 GAAVRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPrsemaGFRRVVNSQKCVRAGGRHNDL 113
Cdd:COG0013 4 SAEIRQKFLDFFE-SKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 114 EDVGRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDsqtgldpDlETRDIWLSL-GVPA 192
Cdd:COG0013 78 ENVGYTARHHTFFEMLGNFSFG-DYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDD-------D-EAYDIWKKEiGVPE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 193 SRVLSFGPQENFWEMGDTGPCGPCTEIHYDL----AGGV-GSP-----QLVELWNLVFMQHYREADGSLQLLPQRHVDTG 262
Cdd:COG0013 149 ERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeyGGGPpGSPgedgdRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 263 MGLERLVAVLQGKRSTYDTDLFSPLLDAIHQscgappYSGRVGAADEgRIDTAYRVVADHIRTLSVCIADGVSPGMSGAP 342
Cdd:COG0013 229 MGLERIAAVLQGVHSNYETDLFRPLIEAAAE------LTGVKYGADE-EDDVSLRVIADHIRAVAFLIADGVLPSNEGRG 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 343 LVLRRILRRAVRYSTEV-LQAPpgFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRL 421
Cdd:COG0013 302 YVLRRILRRAVRHGRLLgIKEP--FLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 422 --GPSDLFPAEVAWslslsgNL----GIPLDLVELMLEEKGVKLDTAGLEQL--AQKEaqhRAQQAEADQEDRLCLDVha 493
Cdd:COG0013 380 kaAGGKVLSGEDAF------KLydtyGFPLDLTEEIARERGLTVDEEGFEAAmeEQRE---RARAAAKFSGDAAVDGV-- 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 494 LEELHRQGIPTTddspkynYTlhpnGdYEFGLCEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYL 573
Cdd:COG0013 449 WRELLEEGGPTE-------FV----G-YDTLEAEAKVLALVKD-GELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTI 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 574 VRTGQQdmlFPVAGAQ-LCGGFILHEA-MAPERLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSH 651
Cdd:COG0013 516 EGDGGV---FEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 652 LNPERLRFDVATQTLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAhTARIPGLRSL-DEVYPDpvrvvsvgvpvahalg 730
Cdd:COG0013 593 VAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLD-EAKALGAMALfGEKYGD---------------- 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 731 pasqaamhT---------SVELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGEqaqQAREVGQSLSQEVEAASER 801
Cdd:COG0013 656 --------EvrvvsigdfSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGE---AALEYLREQEALLKELAEL 724
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 802 LSQGSRDLPEahRLSKdigrltevaesavipqwqrqeLQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSE--G-PL 878
Cdd:COG0013 725 LKAPPEELPE--RVEA---------------------LLEELKELEKE----LEQLKAKLASAAADDLLAQAEEigGvKV 777
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 879 IVDTVSAESLSVLVKVVRQLCKQAPSISVLLLSPQPtGSVLCACQVAQDATP-TFTAEAWALAVCSHMGGKAWGSRVVAQ 957
Cdd:COG0013 778 LAARVEGVDAKDLRDLADDLKDKLGSGVVVLASVAD-GKVSLVAGVTKDLVKkGLKAGDLVKEVAKIVGGGGGGRPDMAQ 856
|
970 980
....*....|....*....|....
gi 115502845 958 GTG-HTADLEAALGTARAYALSQL 980
Cdd:COG0013 857 AGGkDPSKLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
37-960 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 654.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRDRhGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVVNSQKCVRAggrhNDLEDV 116
Cdd:TIGR00344 2 IRQTFLDFFKEK-GHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtgldpdlETRDIWLSLGVPASRVL 196
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDE--------EAYKIWEKIGIPADRII 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 197 SFGPQENFWEMGDtGPCGPCTEIHYDLAGG-VGSP-----QLVELWNLVFMQHYREADGSLQLLPQRHVDTGMGLERLVA 270
Cdd:TIGR00344 143 KCDAKDNFWDMGD-GPCGPCTEIYYDFVGGkPGEPleendRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVA 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 271 VLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSGRVGAADEGRIDT--AYRVVADHIRTLSVCIADGVSPGMSGAPLVLRRI 348
Cdd:TIGR00344 222 VLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEDlrSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 349 LRRAVRYStEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLGpSDLFP 428
Cdd:TIGR00344 302 IRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTG-KKELD 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 429 AEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQLAQkEAQHRAQQAEADQEDrlcldvhaLEELHRqgIPTTDDS 508
Cdd:TIGR00344 380 GEDAFKLYDT--YGFPVELTKEIAEERGLTVDMPGFEALMA-EQRERSKQNSQFQEQ--------EIALVN--VYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 509 PKYNYTlhpngdyEFglcEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLVrtgQQDMLFPVAGA 588
Cdd:TIGR00344 447 LGYDDL-------EF---EAKVIGLFDD-GYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI---ANDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 589 QLCGGFILHEA-MAPERLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFDVATQTLL 667
Cdd:TIGR00344 513 QKPNGVVFHFGeVEGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 668 TTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLRSLDEVYPDPVRVVSVGVPVAhalgpasqaamhtSVELCCGT 747
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYVPGEKVRVVSVGDF-------------SVELCGGT 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 748 HLLSTGAVGDLVIIGERQLVKGITRLLAITGEQAQQArevgqslsqeVEAASERLSQgsrdlpEAHRLSKDIGRLTEVAE 827
Cdd:TIGR00344 660 HVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEY----------LNEQEDKLKE------LADILKVTPNELPKKVE 723
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 828 SavipqwqrqeLQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSE---GPLIVDTVSAESLSVLVKVVRQLCKQAPS 904
Cdd:TIGR00344 724 R----------FFEEWKALQKE----LESLKLKIADQKIDELKDKAETingVKVLVEVVDAKDMKSLKTMADRLKSKLGS 789
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*..
gi 115502845 905 iSVLLLSPQPTGSVLCACQVAQDA-TPTFTAEAWALAVCSHMGGKAWGSRVVAQGTG 960
Cdd:TIGR00344 790 -AIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
37-619 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 627.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagFRRVVNSQKCVRAGgrhnDLEDV 116
Cdd:pfam01411 2 IRQTFLDFFE-KKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAKPP----YNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtgldpdlETRDIWLSL-GVPASRV 195
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFG-DYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 196 LSFGPQENFWEMGDTGPCGPCTEIHYD--LAGGVGSPQ---------LVELWNLVFMQHYREADGSLQLLPQRHVDTGMG 264
Cdd:pfam01411 144 LRFGDKDNFWEMGDTGPCGPCSEIDYDrgEEIGGWDSGgtptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 265 LERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSgrvgaadEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLV 344
Cdd:pfam01411 224 LERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYV 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 345 LRRILRRAVRYStEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLG-P 423
Cdd:pfam01411 297 LRRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkG 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 424 SDLFPAEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQlAQKEAQHRAQQAEadQEDRLCLDVHALEELhrqgiP 503
Cdd:pfam01411 376 KKTLPGEDAFKLYDT--YGFPVDLTKEIAEERGLKVDMPGFEY-AMVEQRERSKQAV--KEKGEKLDVSALKEL-----P 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 504 TTDDSPKYNYTlhpngdyefgLCEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLVRTGQqdmLF 583
Cdd:pfam01411 446 ATTEFLGYDDL----------ESEAKILALPKD-GEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGG---EF 511
|
570 580 590
....*....|....*....|....*....|....*..
gi 115502845 584 PVAGAQLCGGFILHEAMAPE-RLQVGDQVQLYVDKAW 619
Cdd:pfam01411 512 RVTDVQKYGGVVVHKGKLESgKLKVGDKVIAVIDEDR 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
37-275 |
1.15e-111 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 343.96 E-value: 1.15e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVVNSQKCVRAGGRHNdledV 116
Cdd:cd00673 4 IRETFLSFFE-KKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN----V 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDsqtgldpDLETRDIWLSLGVPASRVL 196
Cdd:cd00673 74 GKTGRHHTFFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 197 SFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGS--------PQLVELWNLVFMQHYREADGSLQLLPQRHVDTGMGLERL 268
Cdd:cd00673 146 RIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAaslpneddDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 115502845 269 VAVLQGK 275
Cdd:cd00673 226 VWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
740-773 |
3.73e-07 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 47.38 E-value: 3.73e-07
10 20 30
....*....|....*....|....*....|....
gi 115502845 740 SVELCCGTHLLSTGAVGDLVIIGERQLVKGITRL 773
Cdd:smart00863 10 SVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
34-978 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 884.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 34 GAAVRDAFLSFFRDRhGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVVNSQKCVRAGGRHNDL 113
Cdd:PLN02900 13 GDRIRRTFLSFFESK-GHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 114 EDVGRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtGLDPDLETRDIWLSLgVPAS 193
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFG-DYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDE--KQAPDDEARAIWLDY-LPEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 194 RVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGSPQLV--------ELWNLVFMQHYREADGSLQLLPQRHVDTGMGL 265
Cdd:PLN02900 168 RVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVnnddprfiEIWNLVFIQFNREADGSLKPLPAKHVDTGMGL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 266 ERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSGRVGAADEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLVL 345
Cdd:PLN02900 248 ERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 346 RRILRRAVRYSTEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLGPSD 425
Cdd:PLN02900 328 RRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAAAKANG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 426 --LFPAEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQlAQKEAQHRAQQAEADQED-RLCLDVHALEELHRQGI 502
Cdd:PLN02900 408 gpVLSGKDAFLLYDT--YGFPVDLTELMAEERGVTVDMEGFEA-AMEEARERSRAAHLKAGGgAIELAAEATSWLQKQGV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 503 PTTDDSPKYNYTLHPngdyefglcEARVLQLYSETGtAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLvrTGQQDML 582
Cdd:PLN02900 485 AATDDFLKYDWLSDH---------EAVVKAILTGGG-FVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVL--EGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 583 FPVAGAQLCGGFILHEAMAPE-RLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFDV 661
Cdd:PLN02900 553 VEVSDVQKAGGFVLHIGTVTEgSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDF 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 662 ATQTLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLRSL-DEVYPDPVRVVsvgvpvahALGPasqaamHTS 740
Cdd:PLN02900 633 SHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVfGEKYPDPVRVV--------SVGG------VYS 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 741 VELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGEQAQQAREVGQSLSQEVEAASErlsqgsrdlPEAHRLSKDIG 820
Cdd:PLN02900 699 MELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALK---------VEGSDLEKKVA 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 821 RLTEVAESAVIPQWQRQELQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSEgplIVDTVSAESLSVLV-------- 892
Cdd:PLN02900 770 SLKSRVDAAVIPAAKKEEIRARVSALQKE----LRAAQKEAAALRAKLAVAKATE---LASKALSAGKSVLVarldvgvd 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 893 -----KVVRQLCKQAPSISVLLLSPQP-TGSVLCACQVAQDATPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTGHTAD- 964
Cdd:PLN02900 843 aaalkEAAEKVIAKLGDPAAVVLSSDEeKGKVSLVAAVPPGVVKKgLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEk 922
|
970
....*....|....
gi 115502845 965 LEAALGTARAYALS 978
Cdd:PLN02900 923 LDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
34-980 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 754.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 34 GAAVRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPrsemaGFRRVVNSQKCVRAGGRHNDL 113
Cdd:COG0013 4 SAEIRQKFLDFFE-SKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 114 EDVGRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDsqtgldpDlETRDIWLSL-GVPA 192
Cdd:COG0013 78 ENVGYTARHHTFFEMLGNFSFG-DYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDD-------D-EAYDIWKKEiGVPE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 193 SRVLSFGPQENFWEMGDTGPCGPCTEIHYDL----AGGV-GSP-----QLVELWNLVFMQHYREADGSLQLLPQRHVDTG 262
Cdd:COG0013 149 ERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeyGGGPpGSPgedgdRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 263 MGLERLVAVLQGKRSTYDTDLFSPLLDAIHQscgappYSGRVGAADEgRIDTAYRVVADHIRTLSVCIADGVSPGMSGAP 342
Cdd:COG0013 229 MGLERIAAVLQGVHSNYETDLFRPLIEAAAE------LTGVKYGADE-EDDVSLRVIADHIRAVAFLIADGVLPSNEGRG 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 343 LVLRRILRRAVRYSTEV-LQAPpgFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRL 421
Cdd:COG0013 302 YVLRRILRRAVRHGRLLgIKEP--FLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 422 --GPSDLFPAEVAWslslsgNL----GIPLDLVELMLEEKGVKLDTAGLEQL--AQKEaqhRAQQAEADQEDRLCLDVha 493
Cdd:COG0013 380 kaAGGKVLSGEDAF------KLydtyGFPLDLTEEIARERGLTVDEEGFEAAmeEQRE---RARAAAKFSGDAAVDGV-- 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 494 LEELHRQGIPTTddspkynYTlhpnGdYEFGLCEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYL 573
Cdd:COG0013 449 WRELLEEGGPTE-------FV----G-YDTLEAEAKVLALVKD-GELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTI 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 574 VRTGQQdmlFPVAGAQ-LCGGFILHEA-MAPERLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSH 651
Cdd:COG0013 516 EGDGGV---FEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 652 LNPERLRFDVATQTLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAhTARIPGLRSL-DEVYPDpvrvvsvgvpvahalg 730
Cdd:COG0013 593 VAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLD-EAKALGAMALfGEKYGD---------------- 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 731 pasqaamhT---------SVELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGEqaqQAREVGQSLSQEVEAASER 801
Cdd:COG0013 656 --------EvrvvsigdfSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGE---AALEYLREQEALLKELAEL 724
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 802 LSQGSRDLPEahRLSKdigrltevaesavipqwqrqeLQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSE--G-PL 878
Cdd:COG0013 725 LKAPPEELPE--RVEA---------------------LLEELKELEKE----LEQLKAKLASAAADDLLAQAEEigGvKV 777
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 879 IVDTVSAESLSVLVKVVRQLCKQAPSISVLLLSPQPtGSVLCACQVAQDATP-TFTAEAWALAVCSHMGGKAWGSRVVAQ 957
Cdd:COG0013 778 LAARVEGVDAKDLRDLADDLKDKLGSGVVVLASVAD-GKVSLVAGVTKDLVKkGLKAGDLVKEVAKIVGGGGGGRPDMAQ 856
|
970 980
....*....|....*....|....
gi 115502845 958 GTG-HTADLEAALGTARAYALSQL 980
Cdd:COG0013 857 AGGkDPSKLDEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
37-960 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 654.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRDRhGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVVNSQKCVRAggrhNDLEDV 116
Cdd:TIGR00344 2 IRQTFLDFFKEK-GHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtgldpdlETRDIWLSLGVPASRVL 196
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDE--------EAYKIWEKIGIPADRII 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 197 SFGPQENFWEMGDtGPCGPCTEIHYDLAGG-VGSP-----QLVELWNLVFMQHYREADGSLQLLPQRHVDTGMGLERLVA 270
Cdd:TIGR00344 143 KCDAKDNFWDMGD-GPCGPCTEIYYDFVGGkPGEPleendRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVA 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 271 VLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSGRVGAADEGRIDT--AYRVVADHIRTLSVCIADGVSPGMSGAPLVLRRI 348
Cdd:TIGR00344 222 VLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEDlrSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 349 LRRAVRYStEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLGpSDLFP 428
Cdd:TIGR00344 302 IRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTG-KKELD 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 429 AEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQLAQkEAQHRAQQAEADQEDrlcldvhaLEELHRqgIPTTDDS 508
Cdd:TIGR00344 380 GEDAFKLYDT--YGFPVELTKEIAEERGLTVDMPGFEALMA-EQRERSKQNSQFQEQ--------EIALVN--VYPATEF 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 509 PKYNYTlhpngdyEFglcEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLVrtgQQDMLFPVAGA 588
Cdd:TIGR00344 447 LGYDDL-------EF---EAKVIGLFDD-GYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLI---ANDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 589 QLCGGFILHEA-MAPERLQVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFDVATQTLL 667
Cdd:TIGR00344 513 QKPNGVVFHFGeVEGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 668 TTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLRSLDEVYPDPVRVVSVGVPVAhalgpasqaamhtSVELCCGT 747
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYVPGEKVRVVSVGDF-------------SVELCGGT 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 748 HLLSTGAVGDLVIIGERQLVKGITRLLAITGEQAQQArevgqslsqeVEAASERLSQgsrdlpEAHRLSKDIGRLTEVAE 827
Cdd:TIGR00344 660 HVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEY----------LNEQEDKLKE------LADILKVTPNELPKKVE 723
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 828 SavipqwqrqeLQTTLKMLQRRantaIRKLEKGQATEKSQELLKRHSE---GPLIVDTVSAESLSVLVKVVRQLCKQAPS 904
Cdd:TIGR00344 724 R----------FFEEWKALQKE----LESLKLKIADQKIDELKDKAETingVKVLVEVVDAKDMKSLKTMADRLKSKLGS 789
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*..
gi 115502845 905 iSVLLLSPQPTGSVLCACQVAQDA-TPTFTAEAWALAVCSHMGGKAWGSRVVAQGTG 960
Cdd:TIGR00344 790 -AIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
37-619 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 627.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagFRRVVNSQKCVRAGgrhnDLEDV 116
Cdd:pfam01411 2 IRQTFLDFFE-KKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAKPP----YNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDSqtgldpdlETRDIWLSL-GVPASRV 195
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFG-DYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 196 LSFGPQENFWEMGDTGPCGPCTEIHYD--LAGGVGSPQ---------LVELWNLVFMQHYREADGSLQLLPQRHVDTGMG 264
Cdd:pfam01411 144 LRFGDKDNFWEMGDTGPCGPCSEIDYDrgEEIGGWDSGgtptadddrFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 265 LERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAPPYSgrvgaadEGRIDTAYRVVADHIRTLSVCIADGVSPGMSGAPLV 344
Cdd:pfam01411 224 LERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYV 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 345 LRRILRRAVRYStEVLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLG-P 423
Cdd:pfam01411 297 LRRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkG 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 424 SDLFPAEVAWSLSLSgnLGIPLDLVELMLEEKGVKLDTAGLEQlAQKEAQHRAQQAEadQEDRLCLDVHALEELhrqgiP 503
Cdd:pfam01411 376 KKTLPGEDAFKLYDT--YGFPVDLTKEIAEERGLKVDMPGFEY-AMVEQRERSKQAV--KEKGEKLDVSALKEL-----P 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 504 TTDDSPKYNYTlhpngdyefgLCEARVLQLYSEtGTAVASVGAGQRCGLLLDRTNFYAEQGGQASDRGYLVRTGQqdmLF 583
Cdd:pfam01411 446 ATTEFLGYDDL----------ESEAKILALPKD-GEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGG---EF 511
|
570 580 590
....*....|....*....|....*....|....*..
gi 115502845 584 PVAGAQLCGGFILHEAMAPE-RLQVGDQVQLYVDKAW 619
Cdd:pfam01411 512 RVTDVQKYGGVVVHKGKLESgKLKVGDKVIAVIDEDR 548
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
37-779 |
4.90e-114 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 363.32 E-value: 4.90e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRDRhGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMagfrrVVNSQKCVRAGgrhnDLEDV 116
Cdd:PRK01584 6 LRKKYIDFFKSK-GHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTR-----LVDVQKCLRTG----DIDEV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GrDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLT--QVYGIPEDRLWVSYFSGDSQtgLDPDLETRDIWLSLGVPASR 194
Cdd:PRK01584 76 G-DLSHLTFFEMLGNWSLG-AYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEE--IPRDEETASVWESLGIPKDR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 195 VLSFGPQENFW-EMGDTGPCGPCTEIHYDLAG---------GVGSPQLVELWNLVFMQHYREADGSLQLLPQRHVDTGMG 264
Cdd:PRK01584 152 IFYLSREHNWWgPVGETGPCGPDTEIFVDTGKpkcsvncrpTCSCGKYFEIWNNVFMQYNKDEDGNYEELKRKCVDTGMG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 265 LERLVAVLQGKRSTYDTDLFSPLLDAIHQSCGAppysgRVGAADEGriDTAYRVVADHIRTLSVCIAD--GVSPGMSGAP 342
Cdd:PRK01584 232 IERTIAFLQGKSSVYDTEAFTPIIKRIEKISGK-----IYGQNEED--DRSIRIIADHIRAACFILGDpfVVLPSNVGQG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 343 LVLRRILRRAVRYSTEvLQAPPGFLGSLVPVVVETLGSAYPELEKNSVKIASLVSEDEAAFLASLQRGRRIIDRTVKRLG 422
Cdd:PRK01584 305 YVLRRLIRRSIRHAKK-LGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLG 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 423 PSDLFPAEVAWslSLSGNLGIPLDLVELMLEEKGVKLDTAGLEQLAQKeaqHRaqqaeadqedrlcldvhaleELHRQGi 502
Cdd:PRK01584 384 SSKIIPGDIAF--KLYDTYGFPYEITEELASEYGFTVDREGFDEHFKK---HQ--------------------KVSKKG- 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 503 pttddspkynytlhpnGDYEF--GLCEarvlqlYSETGTAVasvgagqrcgllldrtnfyaeqggqasdrgylvrtgqqd 580
Cdd:PRK01584 438 ----------------ADKVFkgGLAD------HSYETTKL--------------------------------------- 456
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 581 mlfpvagaqlcggfilheamaperlqvgdqvqlyvdkawrmgcmvkHTATHLLSWALRQTLGPTTEQRGSHLNPERLRFD 660
Cdd:PRK01584 457 ----------------------------------------------HTATHLLHKALRLVLGDHVRQKGSNITAERLRFD 490
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 661 VATQTLLTTEQLRTVESYVQEVVGQDKPVFMEEVPLAHTARIPGLRSLDEVYPDpvrvvsvgVPVAHALGpasqaamHTS 740
Cdd:PRK01584 491 FSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKEVMSLEEAREKGAMALFGEKYED--------IVKVYEID-------GFS 555
|
730 740 750
....*....|....*....|....*....|....*....
gi 115502845 741 VELCCGTHLLSTGAVGDLVIIGERQLVKGITRLLAITGE 779
Cdd:PRK01584 556 KEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAILID 594
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
37-275 |
1.15e-111 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 343.96 E-value: 1.15e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 37 VRDAFLSFFRdRHGHRLVPSATVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSemagfRRVVNSQKCVRAGGRHNdledV 116
Cdd:cd00673 4 IRETFLSFFE-KKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN----V 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 117 GRDLSHHTFFEMLGNWAFGgEYFKEEACSMAWELLTQVYGIPEDRLWVSYFSGDsqtgldpDLETRDIWLSLGVPASRVL 196
Cdd:cd00673 74 GKTGRHHTFFEMLGNFSFG-DYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 197 SFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGS--------PQLVELWNLVFMQHYREADGSLQLLPQRHVDTGMGLERL 268
Cdd:cd00673 146 RIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAaslpneddDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 115502845 269 VAVLQGK 275
Cdd:cd00673 226 VWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
526-773 |
1.24e-32 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 126.85 E-value: 1.24e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 526 CEARVlqlysetgtavasVGAGQRCGLLLDRTNFYAEQGGQASDRGYLVRTGQQdmlFPVAGAQLCGGFILHEAMAPERL 605
Cdd:COG2872 15 FEATV-------------TAVTEEGGVVLDRTAFYPTGGGQPGDTGTLVWDGKE---IRVVDVRKEDGEIVHVLEGAPLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 606 QVGDQVQLYVDKAWRMGCMVKHTATHLLSWALRQTLG-PTTeqrGSHLNPERLR--FDVATqtlLTTEQLRTVESYVQEV 682
Cdd:COG2872 79 EVGDEVTGEIDWERRYRHMRLHTALHLLSAVVYREYGaPVT---GGQIGEDRARidFDLPE---FDEEDLEEIEAEANEL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 683 VGQDKPVFMEEVPLAHTARIPGLRSLDEVYPDPVrvvsvgvpvahaLGPA---------SQAamhtsvelCCGTHLLSTG 753
Cdd:COG2872 153 IAADLPVRIYWITREELEAIPGLVRTMSVLPPPG------------VGRVriveiggvdLQP--------CGGTHVANTG 212
|
250 260
....*....|....*....|.
gi 115502845 754 AVGDLVIIG-ERQlVKGITRL 773
Cdd:COG2872 213 EIGRIKITKiEKK-GKGNRRV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
740-773 |
3.73e-07 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 47.38 E-value: 3.73e-07
10 20 30
....*....|....*....|....*....|....
gi 115502845 740 SVELCCGTHLLSTGAVGDLVIIGERQLVKGITRL 773
Cdd:smart00863 10 SVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
549-651 |
1.26e-06 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 50.47 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 549 RCGLLLDRTNFYAEQGGQASDRGYLVRTGqQDMLFPVAGAQLCGGFILH----------EAMAPERlqvGDQVQLYVDKA 618
Cdd:PLN02961 2 RIALVLDRTIFHPQGGGQPSDTGRIVISG-GDTKFSVQDVRRKDGVVYHygvfegsnpeSASPFEA---GDEVTVTVDES 77
|
90 100 110
....*....|....*....|....*....|....
gi 115502845 619 WRMGCMVKHTATHLLSWALRQT-LGPTTEQRGSH 651
Cdd:PLN02961 78 RRKLHSRLHSAGHLLDVCMARVgLGPLEPGKGYH 111
|
|
| class_II_aaRS-like_core |
cd00768 |
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ... |
92-268 |
2.05e-05 |
|
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain] Cd Length: 211 Bit Score: 46.73 E-value: 2.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 92 AGFRRVVNSQKCVRAGGRHndledvgRDLSHHTFFEMLGNWAFGGE----YFKEEACSMAWELLtQVYGIPEDRLWVsyf 167
Cdd:cd00768 73 KLPLRLAEIGPAFRNEGGR-------RGLRRVREFTQLEGEVFGEDgeeaSEFEELIELTEELL-RALGIKLDIVFV--- 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115502845 168 sgdsqtgldpdletrdiwlslgvpasrvlsfgpqENFWEMGDTGPCGPCTEIHYDLAGGVGspqlVELWNLVFMQH---- 243
Cdd:cd00768 142 ----------------------------------EKTPGEFSPGGAGPGFEIEVDHPEGRG----LEIGSGGYRQDeqar 183
|
170 180 190
....*....|....*....|....*....|
gi 115502845 244 -----YREADGSLQLLPqrHVDTGMGLERL 268
Cdd:cd00768 184 aadlyFLDEALEYRYPP--TIGFGLGLERL 211
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
740-773 |
1.77e-04 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 39.74 E-value: 1.77e-04
10 20 30
....*....|....*....|....*....|....
gi 115502845 740 SVELCCGTHLLSTGAVGDLVIIGERQLVKGITRL 773
Cdd:pfam07973 10 DVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| |
