NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|75220701|sp|Q38845|]
View 

RecName: Full=Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Short=AtA alpha; Short=PP2A, subunit A, alpha isoform; Short=PR-65 A; AltName: Full=Protein ROOTS CURL IN NAPHTHYLPHTHALAMIC ACID 1; AltName: Full=Protein enhancer of ethylene-response 1

Protein Classification

HEAT repeat domain-containing protein( domain architecture ID 11444215)

HEAT repeat domain-containing protein may function as a scaffold, anchoring and/or adaptor protein

CATH:  1.25.10.110
Gene Ontology:  GO:0005515
PubMed:  35552740|10378263
SCOP:  4001283

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
170-301 1.18e-08

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.86  E-value: 1.18e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 170 QLCKDDMPMVRRAAASNLGKFATTVESTFLIaeimtmfdDLTKDDQDSVRLLAVEgcaALGKLLEPqdcvaRILPVIVNF 249
Cdd:COG1413  23 AALADEDPDVRAAAARALGRLGDPRAVPALL--------EALKDPDPEVRAAAAE---ALGRIGDP-----EAVPALIAA 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 75220701 250 SQDKSWRVRYMVANQLYELceavgpdcTRTDLVPAYVRLLRDNEAEVRIAAA 301
Cdd:COG1413  87 LKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAA 130
HEAT COG1413
HEAT repeat [General function prediction only];
257-419 9.13e-06

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 45.39  E-value: 9.13e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 257 VRYMVANQLYELCEAvgpdctrtDLVPAYVRLLRDNEAEVRIAAAgkvtKFCRLLNPELAIQHILpcvkELSSDSSQHVR 336
Cdd:COG1413   1 VRRAAARALGRLGDP--------AAVPALIAALADEDPDVRAAAA----RALGRLGDPRAVPALL----EALKDPDPEVR 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 337 SALASVIMGMAPilgkdstiEHLLPIFLSLLKDEFPDVRLNIISKLDQVNqvigidllSQSLLPAIVELAEDRHWRVRLA 416
Cdd:COG1413  65 AAAAEALGRIGD--------PEAVPALIAALKDEDPEVRRAAAEALGRLG--------DPAAVPALLEALKDPDWEVRRA 128


                ...
gi 75220701 417 IIE 419
Cdd:COG1413 129 AAR 131
HEAT COG1413
HEAT repeat [General function prediction only];
350-503 1.25e-04

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 42.31  E-value: 1.25e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 350 LGKDSTIEHLLPiflsLLKDEFPDVRLNIIskldqvnQVIGiDLLSQSLLPAIVELAEDRHWRVRLAIIEyvplLASQLG 429
Cdd:COG1413  12 LGDPAAVPALIA----ALADEDPDVRAAAA-------RALG-RLGDPRAVPALLEALKDPDPEVRAAAAE----ALGRIG 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75220701 430 igffDDKLGALCMQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISLMA 503
Cdd:COG1413  76 ----DPEAVPALIAALKDEDPEVRRAAAEALGRLGDP--------AAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
442-580 1.71e-03

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 1.71e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 442 MQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISlmapvmgsEITCSKFLPVVVE 521
Cdd:COG1413  22 IAALADEDPDVRAAAARALGRLGDP--------RAVPALLEALKDPDPEVRAAAAEALG--------RIGDPEAVPALIA 85

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 75220701 522 ASKDRVPNIKFNVAKLLQSLipivdqsvVDKTIRQCLVDLSEDPDVDVRYFANQALNSI 580
Cdd:COG1413  86 ALKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAARALGRL 136
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
170-301 1.18e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.86  E-value: 1.18e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 170 QLCKDDMPMVRRAAASNLGKFATTVESTFLIaeimtmfdDLTKDDQDSVRLLAVEgcaALGKLLEPqdcvaRILPVIVNF 249
Cdd:COG1413  23 AALADEDPDVRAAAARALGRLGDPRAVPALL--------EALKDPDPEVRAAAAE---ALGRIGDP-----EAVPALIAA 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 75220701 250 SQDKSWRVRYMVANQLYELceavgpdcTRTDLVPAYVRLLRDNEAEVRIAAA 301
Cdd:COG1413  87 LKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAA 130
HEAT COG1413
HEAT repeat [General function prediction only];
257-419 9.13e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 45.39  E-value: 9.13e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 257 VRYMVANQLYELCEAvgpdctrtDLVPAYVRLLRDNEAEVRIAAAgkvtKFCRLLNPELAIQHILpcvkELSSDSSQHVR 336
Cdd:COG1413   1 VRRAAARALGRLGDP--------AAVPALIAALADEDPDVRAAAA----RALGRLGDPRAVPALL----EALKDPDPEVR 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 337 SALASVIMGMAPilgkdstiEHLLPIFLSLLKDEFPDVRLNIISKLDQVNqvigidllSQSLLPAIVELAEDRHWRVRLA 416
Cdd:COG1413  65 AAAAEALGRIGD--------PEAVPALIAALKDEDPEVRRAAAEALGRLG--------DPAAVPALLEALKDPDWEVRRA 128


                ...
gi 75220701 417 IIE 419
Cdd:COG1413 129 AAR 131
HEAT COG1413
HEAT repeat [General function prediction only];
350-503 1.25e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 42.31  E-value: 1.25e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 350 LGKDSTIEHLLPiflsLLKDEFPDVRLNIIskldqvnQVIGiDLLSQSLLPAIVELAEDRHWRVRLAIIEyvplLASQLG 429
Cdd:COG1413  12 LGDPAAVPALIA----ALADEDPDVRAAAA-------RALG-RLGDPRAVPALLEALKDPDPEVRAAAAE----ALGRIG 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75220701 430 igffDDKLGALCMQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISLMA 503
Cdd:COG1413  76 ----DPEAVPALIAALKDEDPEVRRAAAEALGRLGDP--------AAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 356-461 7.11e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.86  E-value: 7.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701   356 IEHLLPIflsLLKDEFPDVRLNIISKLDQVNqvigidllSQSLLPAIVELAEDRHWRVRLAIIEYvpllasqlgIGFFDD 435
Cdd:pfam13646   1 LPALLQA---LLRDPDPEVRAAAIRALGRIG--------DPEAVPALLELLKDEDPAVRRAAAEA---------LGKIGD 60

                          90       100
                  ....*....|....*....|....*...
gi 75220701   436 K--LGALCMQWLQDKVYSIREAAANNLK 461
Cdd:pfam13646  61 PeaLPALLELLRDDDDDVVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
442-580 1.71e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 1.71e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 442 MQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISlmapvmgsEITCSKFLPVVVE 521
Cdd:COG1413  22 IAALADEDPDVRAAAARALGRLGDP--------RAVPALLEALKDPDPEVRAAAAEALG--------RIGDPEAVPALIA 85

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 75220701 522 ASKDRVPNIKFNVAKLLQSLipivdqsvVDKTIRQCLVDLSEDPDVDVRYFANQALNSI 580
Cdd:COG1413  86 ALKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 210-301 2.56e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 37.32  E-value: 2.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701   210 LTKDDQDSVRLLAVEgcaALGKLLEPQdcvarILPVIVNFSQDKSWRVRYMVANQLYELCEAvgpdctrtDLVPAYVRLL 289
Cdd:pfam13646   8 LLRDPDPEVRAAAIR---ALGRIGDPE-----AVPALLELLKDEDPAVRRAAAEALGKIGDP--------EALPALLELL 71

                          90
                  ....*....|...
gi 75220701   290 R-DNEAEVRIAAA 301
Cdd:pfam13646  72 RdDDDDVVRAAAA 84
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
170-301 1.18e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 53.86  E-value: 1.18e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 170 QLCKDDMPMVRRAAASNLGKFATTVESTFLIaeimtmfdDLTKDDQDSVRLLAVEgcaALGKLLEPqdcvaRILPVIVNF 249
Cdd:COG1413  23 AALADEDPDVRAAAARALGRLGDPRAVPALL--------EALKDPDPEVRAAAAE---ALGRIGDP-----EAVPALIAA 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 75220701 250 SQDKSWRVRYMVANQLYELceavgpdcTRTDLVPAYVRLLRDNEAEVRIAAA 301
Cdd:COG1413  87 LKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAA 130
HEAT COG1413
HEAT repeat [General function prediction only];
102-265 3.14e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 3.14e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 102 VREKAVESLCKIGSQmkendlvESFVPLVKRLAGGEWFAARVSACGIFHVAYQGCTDVLKtelratysQLCKDDMPMVRR 181
Cdd:COG1413   1 VRRAAARALGRLGDP-------AAVPALIAALADEDPDVRAAAARALGRLGDPRAVPALL--------EALKDPDPEVRA 65

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 182 AAASNLGKFATTVESTFLIAeimtmfddLTKDDQDSVRLLAVEgcaALGKLLEPqdcvaRILPVIVNFSQDKSWRVRYMV 261
Cdd:COG1413  66 AAAEALGRIGDPEAVPALIA--------ALKDEDPEVRRAAAE---ALGRLGDP-----AAVPALLEALKDPDWEVRRAA 129


                ....
gi 75220701 262 ANQL 265
Cdd:COG1413 130 ARAL 133
HEAT COG1413
HEAT repeat [General function prediction only];
257-419 9.13e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 45.39  E-value: 9.13e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 257 VRYMVANQLYELCEAvgpdctrtDLVPAYVRLLRDNEAEVRIAAAgkvtKFCRLLNPELAIQHILpcvkELSSDSSQHVR 336
Cdd:COG1413   1 VRRAAARALGRLGDP--------AAVPALIAALADEDPDVRAAAA----RALGRLGDPRAVPALL----EALKDPDPEVR 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 337 SALASVIMGMAPilgkdstiEHLLPIFLSLLKDEFPDVRLNIISKLDQVNqvigidllSQSLLPAIVELAEDRHWRVRLA 416
Cdd:COG1413  65 AAAAEALGRIGD--------PEAVPALIAALKDEDPEVRRAAAEALGRLG--------DPAAVPALLEALKDPDWEVRRA 128


                ...
gi 75220701 417 IIE 419
Cdd:COG1413 129 AAR 131
HSH155 COG5181
U2 snRNP spliceosome subunit [RNA processing and modification];
253-568 1.62e-05

U2 snRNP spliceosome subunit [RNA processing and modification];


Pssm-ID: 227508 [Multi-domain]  Cd Length: 975  Bit Score: 48.02  E-value: 1.62e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 253 KSWRVRYMVANQLYELCEAVGpdCTR----TDLVPAYVRLLRDNEAEVRIAAAGKVTKFCRLLNPeLAIQHILPCVKELS 328
Cdd:COG5181 329 KSWEARHTGIRIAQQICELLG--RSRlshlGPLLKCISKLLKDRSRFVRIDTANALSYLAELVGP-YGIEQFDEVLCPLW 405

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 329 SDSSQHVRSALASVIMGMAPI--------LGKDSTiEHLlPIFLSLLK---DEFPDVRLNIISKLDQVNQVIGIDLLSQs 397
Cdd:COG5181 406 EGASQHRGKELVSFLKAMGFIiplmspeyACHDTR-EHM-EIVFREFKspdEEMKKDLLVVERICDKVGTDTPWKLRDQ- 482

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 398 LLPAIVElaedRHWRVRLA--------IIEYVPLLASQLGIGFFDDKLgalcMQWLQDKVYSIREAAANNLKRLAEEFGP 469
Cdd:COG5181 483 VSPEFFS----PFWRRRSAgdrrsykqVVLTTVILAKMGGDPRVSRKI----LEYYSDEPEPYRKMNAGLVSRIFSRLGR 554

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 470 EWAMQHLVPQVLDMVNNPhYLHRMMVLRAI--SLMAPVMGSEITCSKFLPVVVEAS----KDRVPNIKFNVAKLLQSLIP 543
Cdd:COG5181 555 LGFDERLEERLYDSILNA-FQEQDTTVGLIlpCFSTVLVSLEFRGKPHLSMIVSTIlkllRSKPPDVRIRAADLMGSLAK 633

                       330       340
                ....*....|....*....|....*
gi 75220701 544 IVDQSVVDKTIRQCLVDLSEDPDVD 568
Cdd:COG5181 634 VLKACGETKELAKLGNILYENLGED 658
HEAT COG1413
HEAT repeat [General function prediction only];
350-503 1.25e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 42.31  E-value: 1.25e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 350 LGKDSTIEHLLPiflsLLKDEFPDVRLNIIskldqvnQVIGiDLLSQSLLPAIVELAEDRHWRVRLAIIEyvplLASQLG 429
Cdd:COG1413  12 LGDPAAVPALIA----ALADEDPDVRAAAA-------RALG-RLGDPRAVPALLEALKDPDPEVRAAAAE----ALGRIG 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75220701 430 igffDDKLGALCMQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISLMA 503
Cdd:COG1413  76 ----DPEAVPALIAALKDEDPEVRRAAAEALGRLGDP--------AAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 356-461 7.11e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.86  E-value: 7.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701   356 IEHLLPIflsLLKDEFPDVRLNIISKLDQVNqvigidllSQSLLPAIVELAEDRHWRVRLAIIEYvpllasqlgIGFFDD 435
Cdd:pfam13646   1 LPALLQA---LLRDPDPEVRAAAIRALGRIG--------DPEAVPALLELLKDEDPAVRRAAAEA---------LGKIGD 60

                          90       100
                  ....*....|....*....|....*...
gi 75220701   436 K--LGALCMQWLQDKVYSIREAAANNLK 461
Cdd:pfam13646  61 PeaLPALLELLRDDDDDVVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
296-464 1.48e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 39.23  E-value: 1.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 296 VRIAAAGKVTKfcrlLNPELAIQHILPCVKelssDSSQHVRSALASVImGMapiLGKDSTIEHLLpiflSLLKDEFPDVR 375
Cdd:COG1413   1 VRRAAARALGR----LGDPAAVPALIAALA----DEDPDVRAAAARAL-GR---LGDPRAVPALL----EALKDPDPEVR 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 376 LNIISKLdqvnqvigIDLLSQSLLPAIVELAEDRHWRVRLAIIEyvpllasqlGIGFFDDK--LGALcMQWLQDKVYSIR 453
Cdd:COG1413  65 AAAAEAL--------GRIGDPEAVPALIAALKDEDPEVRRAAAE---------ALGRLGDPaaVPAL-LEALKDPDWEVR 126

                       170
                ....*....|.
gi 75220701 454 EAAANNLKRLA 464
Cdd:COG1413 127 RAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
442-580 1.71e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 1.71e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701 442 MQWLQDKVYSIREAAANNLKRLAEEfgpewamqHLVPQVLDMVNNPHYLHRMMVLRAISlmapvmgsEITCSKFLPVVVE 521
Cdd:COG1413  22 IAALADEDPDVRAAAARALGRLGDP--------RAVPALLEALKDPDPEVRAAAAEALG--------RIGDPEAVPALIA 85

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 75220701 522 ASKDRVPNIKFNVAKLLQSLipivdqsvVDKTIRQCLVDLSEDPDVDVRYFANQALNSI 580
Cdd:COG1413  86 ALKDEDPEVRRAAAEALGRL--------GDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 210-301 2.56e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 37.32  E-value: 2.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75220701   210 LTKDDQDSVRLLAVEgcaALGKLLEPQdcvarILPVIVNFSQDKSWRVRYMVANQLYELCEAvgpdctrtDLVPAYVRLL 289
Cdd:pfam13646   8 LLRDPDPEVRAAAIR---ALGRIGDPE-----AVPALLELLKDEDPAVRRAAAEALGKIGDP--------EALPALLELL 71

                          90
                  ....*....|...
gi 75220701   290 R-DNEAEVRIAAA 301
Cdd:pfam13646  72 RdDDDDVVRAAAA 84
HEAT pfam02985
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see ...
 242-272 5.00e-03

HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514).


Pssm-ID: 460773  Cd Length: 31  Bit Score: 34.81  E-value: 5.00e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 75220701   242 ILPVIVNFSQDKSWRVRYMVANQLYELCEAV 272
Cdd:pfam02985   1 LLPLLLKLLNDPSPEVREAAAEALGELAEVL 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH