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Conserved domains on  [gi|81865662|sp|Q80T21|]
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RecName: Full=ADAMTS-like protein 4; Short=ADAMTSL-4; AltName: Full=Thrombospondin repeat-containing protein 1; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 450-563 4.41e-31

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


:

Pssm-ID: 461796  Cd Length: 115  Bit Score: 118.06  E-value: 4.41e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    450 LVSGNLTdRGGPLGYQKILWIPAGASHLHISQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYTAIGTVFQYNRPPREe 528
Cdd:pfam05986    1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 81865662    529 gkGESLSAEGPTTQPVDVYMIFQED---NPGVFYQYVI 563
Cdd:pfam05986   79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 691-747 1.82e-15

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 71.33  E-value: 1.82e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    691 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQPCQLHLC 747
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 876-932 1.64e-13

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 65.94  E-value: 1.64e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    876 WFTGPWSECSSECGSGTQHRDIICVSKLGAEfnVTSPSNCSHLPRPPALQPCQGQAC 932
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNLKPC 55
PLAC pfam08686
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ...
 995-1024 8.62e-11

PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.


:

Pssm-ID: 462560  Cd Length: 31  Bit Score: 57.55  E-value: 8.62e-11
                           10        20        30
                   ....*....|....*....|....*....|
gi 81865662    995 CKDSSPHCPLVVQARLCVYPYYTTTCCRSC 1024
Cdd:pfam08686    1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 809-870 2.78e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.78e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81865662    809 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 870
Cdd:pfam19030    1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 936-987 5.45e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 5.45e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 81865662    936 WFSTLWSPCSRSCQGGMQTREVQC---LSGNQTLSSRCPPHLRPSRKRPCNSQPC 987
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCvqkGGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 755-805 5.76e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 50.14  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 81865662    755 PWSQCSVRCGRGQRSRQVRCVGSNGDEVDKQECASGPPPPPSREACDMGPC 805
Cdd:pfam19030    5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 161-360 2.71e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.94  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   161 PLHRSRRHphRPGQPKNSSTGE------GMVPSQPPSTELASEKHGPHMQPPEPRSHSAETPRSGTAQTEVLPRTSSAPS 234
Cdd:PHA03247 2580 PAVTSRAR--RPDAPPQSARPRapvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPA 2657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   235 YTGTPAPTSSFGDSRSFQGSL---GPRMPPSPGSWSSPQGAERRHPPPFSPVPRSQQ-SRRHWRPPGPHRSPDGWLPLTR 310
Cdd:PHA03247 2658 PGRVSRPRRARRLGRAAQASSppqRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHAlVSATPLPPGPAAARQASPALPA 2737

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 81865662   311 DSSPLWSIFAPSIPAPNCSGESEQMRACSQEPCPPEQP---DPRALQCAAFDS 360
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPaagPPRRLTRPAVAS 2790
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 46-70 8.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


:

Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.03  E-value: 8.16e-05
                            10        20
                    ....*....|....*....|....*
gi 81865662      46 WGPWGRWASCSQPCGVGVQRRSRTC 70
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSC 25
ADAMTS_CR_3 super family cl41950
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 354-448 2.10e-04

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


The actual alignment was detected with superfamily member pfam19236:

Pssm-ID: 437068  Cd Length: 115  Bit Score: 42.00  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    354 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGRCL 421
Cdd:pfam19236    9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88

                           90       100
                   ....*....|....*....|....*..
gi 81865662    422 SPGCDGVLGSGRRPDGCGVCGGDGSTC 448
Cdd:pfam19236   89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 638-687 2.59e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 39.74  E-value: 2.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 81865662    638 SECSASCGKGVWHPIFLCISRESGEELDEQSCAVGARPPASpEPCHGPPC 687
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
 
Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 450-563 4.41e-31

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


Pssm-ID: 461796  Cd Length: 115  Bit Score: 118.06  E-value: 4.41e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    450 LVSGNLTdRGGPLGYQKILWIPAGASHLHISQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYTAIGTVFQYNRPPREe 528
Cdd:pfam05986    1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 81865662    529 gkGESLSAEGPTTQPVDVYMIFQED---NPGVFYQYVI 563
Cdd:pfam05986   79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 691-747 1.82e-15

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 71.33  E-value: 1.82e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    691 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQPCQLHLC 747
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 876-932 1.64e-13

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 65.94  E-value: 1.64e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    876 WFTGPWSECSSECGSGTQHRDIICVSKLGAEfnVTSPSNCSHLPRPPALQPCQGQAC 932
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNLKPC 55
PLAC pfam08686
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ...
 995-1024 8.62e-11

PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.


Pssm-ID: 462560  Cd Length: 31  Bit Score: 57.55  E-value: 8.62e-11
                           10        20        30
                   ....*....|....*....|....*....|
gi 81865662    995 CKDSSPHCPLVVQARLCVYPYYTTTCCRSC 1024
Cdd:pfam08686    1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 809-870 2.78e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.78e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81865662    809 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 870
Cdd:pfam19030    1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 936-987 5.45e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 5.45e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 81865662    936 WFSTLWSPCSRSCQGGMQTREVQC---LSGNQTLSSRCPPHLRPSRKRPCNSQPC 987
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCvqkGGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 755-805 5.76e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 50.14  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 81865662    755 PWSQCSVRCGRGQRSRQVRCVGSNGDEVDKQECASGPPPPPSREACDMGPC 805
Cdd:pfam19030    5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
PHA03247 PHA03247
large tegument protein UL36; Provisional
 161-360 2.71e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.94  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   161 PLHRSRRHphRPGQPKNSSTGE------GMVPSQPPSTELASEKHGPHMQPPEPRSHSAETPRSGTAQTEVLPRTSSAPS 234
Cdd:PHA03247 2580 PAVTSRAR--RPDAPPQSARPRapvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPA 2657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   235 YTGTPAPTSSFGDSRSFQGSL---GPRMPPSPGSWSSPQGAERRHPPPFSPVPRSQQ-SRRHWRPPGPHRSPDGWLPLTR 310
Cdd:PHA03247 2658 PGRVSRPRRARRLGRAAQASSppqRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHAlVSATPLPPGPAAARQASPALPA 2737

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 81865662   311 DSSPLWSIFAPSIPAPNCSGESEQMRACSQEPCPPEQP---DPRALQCAAFDS 360
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPaagPPRRLTRPAVAS 2790
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 941-987 2.12e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.96  E-value: 2.12e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 81865662     941 WSPCSRSCQGGMQTREVQCLSGNQTLS-SRCPPHLRpsRKRPCNSQPC 987
Cdd:smart00209    7 WSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 46-70 8.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.03  E-value: 8.16e-05
                            10        20
                    ....*....|....*....|....*
gi 81865662      46 WGPWGRWASCSQPCGVGVQRRSRTC 70
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSC 25
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 747-805 1.66e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 40.26  E-value: 1.66e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*....
gi 81865662     747 CGHWeisSPWSQCSVRCGRGQRSRQVRCVGSNGDeVDKQECasgPPPPPSREACDMGPC 805
Cdd:smart00209    1 WSEW---SEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
ADAMTS_CR_3 pfam19236
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 354-448 2.10e-04

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 42.00  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    354 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGRCL 421
Cdd:pfam19236    9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88

                           90       100
                   ....*....|....*....|....*..
gi 81865662    422 SPGCDGVLGSGRRPDGCGVCGGDGSTC 448
Cdd:pfam19236   89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 638-687 2.59e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 39.74  E-value: 2.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 81865662    638 SECSASCGKGVWHPIFLCISRESGEELDEQSCAVGARPPASpEPCHGPPC 687
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 747-795 1.76e-03

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 42.26  E-value: 1.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 81865662   747 CGHWEissPWSQCSVRCGRGQRSRQ-----VRCVGSNGDEVDKQECASGPPPPP 795
Cdd:PTZ00441  240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEECPVEPEPLP 290
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 47-69 2.59e-03

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 36.87  E-value: 2.59e-03
                           10        20
                   ....*....|....*....|...
gi 81865662     47 GPWGRWASCSQPCGVGVQRRSRT 69
Cdd:pfam19028    4 SEWSEWSECSVTCGGGVQTRTRT 26
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 691-747 6.93e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 35.64  E-value: 6.93e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662     691 WEAGEWTSCSRSCGPGTQHRQLLCRqefgGGGSSVPPERCGHLPRpnITQPCQLHLC 747
Cdd:smart00209    2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
 
Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 450-563 4.41e-31

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


Pssm-ID: 461796  Cd Length: 115  Bit Score: 118.06  E-value: 4.41e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    450 LVSGNLTdRGGPLGYQKILWIPAGASHLHISQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYTAIGTVFQYNRPPREe 528
Cdd:pfam05986    1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 81865662    529 gkGESLSAEGPTTQPVDVYMIFQED---NPGVFYQYVI 563
Cdd:pfam05986   79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 691-747 1.82e-15

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 71.33  E-value: 1.82e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    691 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQPCQLHLC 747
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 876-932 1.64e-13

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 65.94  E-value: 1.64e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662    876 WFTGPWSECSSECGSGTQHRDIICVSKLGAEfnVTSPSNCSHLPRPPALQPCQGQAC 932
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNLKPC 55
PLAC pfam08686
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ...
 995-1024 8.62e-11

PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.


Pssm-ID: 462560  Cd Length: 31  Bit Score: 57.55  E-value: 8.62e-11
                           10        20        30
                   ....*....|....*....|....*....|
gi 81865662    995 CKDSSPHCPLVVQARLCVYPYYTTTCCRSC 1024
Cdd:pfam08686    1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 809-870 2.78e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.78e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81865662    809 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 870
Cdd:pfam19030    1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 936-987 5.45e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 5.45e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 81865662    936 WFSTLWSPCSRSCQGGMQTREVQC---LSGNQTLSSRCPPHLRPSRKRPCNSQPC 987
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCvqkGGGSIVPDSECSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 755-805 5.76e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 50.14  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 81865662    755 PWSQCSVRCGRGQRSRQVRCVGSNGDEVDKQECASGPPPPPSREACDMGPC 805
Cdd:pfam19030    5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
PHA03247 PHA03247
large tegument protein UL36; Provisional
 161-360 2.71e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.94  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   161 PLHRSRRHphRPGQPKNSSTGE------GMVPSQPPSTELASEKHGPHMQPPEPRSHSAETPRSGTAQTEVLPRTSSAPS 234
Cdd:PHA03247 2580 PAVTSRAR--RPDAPPQSARPRapvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPA 2657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   235 YTGTPAPTSSFGDSRSFQGSL---GPRMPPSPGSWSSPQGAERRHPPPFSPVPRSQQ-SRRHWRPPGPHRSPDGWLPLTR 310
Cdd:PHA03247 2658 PGRVSRPRRARRLGRAAQASSppqRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHAlVSATPLPPGPAAARQASPALPA 2737

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 81865662   311 DSSPLWSIFAPSIPAPNCSGESEQMRACSQEPCPPEQP---DPRALQCAAFDS 360
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPaagPPRRLTRPAVAS 2790
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 941-987 2.12e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.96  E-value: 2.12e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 81865662     941 WSPCSRSCQGGMQTREVQCLSGNQTLS-SRCPPHLRpsRKRPCNSQPC 987
Cdd:smart00209    7 WSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 46-70 8.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.03  E-value: 8.16e-05
                            10        20
                    ....*....|....*....|....*
gi 81865662      46 WGPWGRWASCSQPCGVGVQRRSRTC 70
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSC 25
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 747-805 1.66e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 40.26  E-value: 1.66e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*....
gi 81865662     747 CGHWeisSPWSQCSVRCGRGQRSRQVRCVGSNGDeVDKQECasgPPPPPSREACDMGPC 805
Cdd:smart00209    1 WSEW---SEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
ADAMTS_CR_3 pfam19236
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 354-448 2.10e-04

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 42.00  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    354 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGRCL 421
Cdd:pfam19236    9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88

                           90       100
                   ....*....|....*....|....*..
gi 81865662    422 SPGCDGVLGSGRRPDGCGVCGGDGSTC 448
Cdd:pfam19236   89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 638-687 2.59e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 39.74  E-value: 2.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 81865662    638 SECSASCGKGVWHPIFLCISRESGEELDEQSCAVGARPPASpEPCHGPPC 687
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 941-987 2.85e-04

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 39.57  E-value: 2.85e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 81865662    941 WSPCSRSCQGGMQTREVQCLSGNQTLSSRCPPHLrpsRKRPCNSQPC 987
Cdd:pfam19028    9 WSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELL---ERRPCNLPPC 52
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 747-795 1.76e-03

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 42.26  E-value: 1.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 81865662   747 CGHWEissPWSQCSVRCGRGQRSRQ-----VRCVGSNGDEVDKQECASGPPPPP 795
Cdd:PTZ00441  240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEECPVEPEPLP 290
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 47-69 2.59e-03

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 36.87  E-value: 2.59e-03
                           10        20
                   ....*....|....*....|...
gi 81865662     47 GPWGRWASCSQPCGVGVQRRSRT 69
Cdd:pfam19028    4 SEWSEWSECSVTCGGGVQTRTRT 26
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
90-324 4.93e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    90 RPRGQGSRpQTPRDPQSLYRPQPRGRGGPLRAPASQVGREETQEPQGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRHP 169
Cdd:PRK12323  364 RPGQSGGG-AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASAR 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   170 HRPGQPKNSSTGEGM-VPSQPPSTELASEKHGPHMQPPEPRSHSAETprsgTAQTEVLPRTSSAPSYTGTPAPTSSFGDS 248
Cdd:PRK12323  443 GPGGAPAPAPAPAAApAAAARPAAAGPRPVAAAAAAAPARAAPAAAP----APADDDPPPWEELPPEFASPAPAQPDAAP 518

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 81865662   249 RSFQGSLGPRmppSPGSWSSPQGAERRHPPPFSPVPRSQQSRRHWRPPGPHRSPDGWLPLTRDSSplWSIFAPSIP 324
Cdd:PRK12323  519 AGWVAESIPD---PATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGD--WPALAARLP 589
PHA03247 PHA03247
large tegument protein UL36; Provisional
 35-352 5.40e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662    35 PSEEGQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALPLPPRPPRHPEAHRPRGQGSRPQTPRDPQSLYRPQPRG 114
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   115 RGGPLRAPASQVGREETQEPQGAQRFRVRDPIKPGMFGYGRVPFALPLHRSrrhPHRPGQPKNSSTGEGMVPSQPPSTEL 194
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG---PPAPAPPAAPAAGPPRRLTRPAVASL 2791

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   195 ASEKHGPHMqPPEPRSHSAE-TPRSGTAQTEVLPRTSSAPSYTGTPA----PTSSFGDSRSFQGSLGPrmppspgswssp 269
Cdd:PHA03247 2792 SESRESLPS-PWDPADPPAAvLAPAAALPPAASPAGPLPPPTSAQPTapppPPGPPPPSLPLGGSVAP------------ 2858

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   270 QGAERRHPPPFSPV-----PRSQQSRRHWRPPgPHRSPDGwLPLTRDSSPlwSIFAPSIPAPNCSGESEQMRACSQePCP 344
Cdd:PHA03247 2859 GGDVRRRPPSRSPAakpaaPARPPVRRLARPA-VSRSTES-FALPPDQPE--RPPQPQAPPPPQPQPQPPPPPQPQ-PPP 2933


                  ....*...
gi 81865662   345 PEQPDPRA 352
Cdd:PHA03247 2934 PPPPRPQP 2941
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 110-303 6.87e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 6.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   110 PQPRGRGGPLRAPASQVGREETQEPQGAQRfrvrdPIKPGMFGYGRVPFALPLHRSRRHPHRPGQPKNSSTGEGMVPSQP 189
Cdd:PRK07764  603 PASSGPPEEAARPAAPAAPAAPAAPAPAGA-----AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA 677

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81865662   190 PSTElasekhGPHMQPPEPRSHSAETPRSGTAQTEVLPRTSSAPSYTGTPAPTSSFGDSRSFQGSLGPRMPPSPGSWSSP 269
Cdd:PRK07764  678 PAAP------PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDP 751

                         170       180       190
                  ....*....|....*....|....*....|....
gi 81865662   270 QGAERRHPPPFSPVPRSQQSRrhwRPPGPHRSPD 303
Cdd:PRK07764  752 AGAPAQPPPPPAPAPAAAPAA---APPPSPPSEE 782
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 691-747 6.93e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 35.64  E-value: 6.93e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 81865662     691 WEAGEWTSCSRSCGPGTQHRQLLCRqefgGGGSSVPPERCGHLPRpnITQPCQLHLC 747
Cdd:smart00209    2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
47-70 9.20e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 35.09  E-value: 9.20e-03
                           10        20
                   ....*....|....*....|....
gi 81865662     47 GPWGRWASCSQPCGVGVQRRSRTC 70
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGIQVRQRTC 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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