NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|296452893|sp|Q96CW6|]
View 

RecName: Full=Probable RNA polymerase II nuclear localization protein SLC7A6OS; AltName: Full=ADAMS proteinase-related protein; AltName: Full=Solute carrier family 7 member 6 opposite strand transcript

Protein Classification

Iwr1 domain-containing protein( domain architecture ID 10554160)

Iwr1 domain-containing protein such as yeast RNA polymerase II nuclear localization protein Iwr1 which binds RNAP II and regulates nuclear import

Gene Ontology:  GO:0006606|GO:0005634|GO:0005737
PubMed:  21504834|21695216

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.33e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


:

Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.56  E-value: 1.33e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 296452893  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNDDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.33e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.56  E-value: 1.33e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 296452893  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNDDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.33e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.56  E-value: 1.33e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 296452893  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNDDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH