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Conserved domains on  [gi|61214509|sp|Q9B8T9|]
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RecName: Full=NADH-ubiquinone oxidoreductase chain 4L; AltName: Full=NADH dehydrogenase subunit 4L

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 6.35e-38

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 122.35  E-value: 6.35e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 61214509  81 VSNTYGLDYIKNLSLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 6.35e-38

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 122.35  E-value: 6.35e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 61214509  81 VSNTYGLDYIKNLSLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 2.90e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.18  E-value: 2.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509    3 SIFTNIILAFATALLGtLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 61214509   83 NTYGLDYIKNLSLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 6.35e-38

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 122.35  E-value: 6.35e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 61214509  81 VSNTYGLDYIKNLSLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 11-98 5.23e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 76.93  E-value: 5.23e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509  11 AFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGLDYI 90
Cdd:MTH00126 11 AFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVATARTHGTDRL 90


                ....*...
gi 61214509  91 KNLSLLQC 98
Cdd:MTH00126 91 QNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 9.80e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 76.42  E-value: 9.80e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 61214509  81 VSNTYGLDYIKNLSLLQC 98
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 8-98 7.40e-16

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 66.55  E-value: 7.40e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   8 IILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGL 87
Cdd:MTH00067  8 FYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVATTRTHGT 87

                        90
                ....*....|.
gi 61214509  88 DYIKNLSLLQC 98
Cdd:MTH00067 88 DHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 9-96 1.05e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 53.02  E-value: 1.05e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   9 ILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGLD 88
Cdd:MTH00181  6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                ....*...
gi 61214509  89 YIKNLSLL 96
Cdd:MTH00181 86 HLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 2.90e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.18  E-value: 2.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509    3 SIFTNIILAFATALLGtLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 61214509   83 NTYGLDYIKNLSLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 5.11e-09

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 48.76  E-value: 5.11e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 61214509  81 VSNTYGLDYIKNLSLLQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 3-98 2.20e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 44.58  E-value: 2.20e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   3 SIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLtmSFMMPILLLVFAACEAAIGLALLVMVS 82
Cdd:MTH00188  4 SMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEK--ELYLSLVLLTFAACEASVGLALLVSLI 81

                        90
                ....*....|....*.
gi 61214509  83 NTYGLDYIKNLSLLQC 98
Cdd:MTH00188 82 RSHGSDYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 1.16e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 42.91  E-value: 1.16e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   9 ILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLstLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGLD 88
Cdd:MTH00149 10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVM--MFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                        90
                ....*....|
gi 61214509  89 YIKNLSLLQC 98
Cdd:MTH00149 88 YVSSLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-98 1.44e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 40.12  E-value: 1.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHlTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00013  1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAN-QVNGMLAIVLLTFGACEASLGLSLLVL 79

                        90
                ....*....|....*...
gi 61214509  81 VSNTYGLDYIKNLSLLQC 98
Cdd:MTH00013 80 MTRSYGNDMLKSLTSNKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 8-92 2.37e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 39.37  E-value: 2.37e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   8 IILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLstLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGL 87
Cdd:MTH00162  7 FLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFL--LFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSHGN 84


                ....*
gi 61214509  88 DYIKN 92
Cdd:MTH00162 85 DYFSS 89
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 1-97 4.39e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 33.47  E-value: 4.39e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61214509   1 MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVM 80
Cdd:MTH00180  2 YYEYLTVGIILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVA 81

                        90
                ....*....|....*..
gi 61214509  81 VSNTYGLDYIKNLSLLQ 97
Cdd:MTH00180 82 YYRIRGTIAVKSLNLLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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