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Conserved domains on  [gi|21542325|sp|Q9UII5|]
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RecName: Full=Zinc finger protein 107; AltName: Full=Zinc finger protein 588; AltName: Full=Zinc finger protein ZFD25

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
438-750 2.06e-12

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.11  E-value: 2.06e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 513
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 514 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 593
Cdd:COG5048 112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 594 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 673
Cdd:COG5048 189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 674 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 740
Cdd:COG5048 265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                       330
                ....*....|
gi 21542325 741 IHTGEKPYKC 750
Cdd:COG5048 345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
130-508 1.57e-10

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.33  E-value: 1.57e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 130 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKC--EECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQA------- 200
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 201 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 263
Cdd:COG5048 112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 264 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 340
Cdd:COG5048 192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 341 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 407
Cdd:COG5048 268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 408 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 476
Cdd:COG5048 348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                       410       420       430
                ....*....|....*....|....*....|..
gi 21542325 477 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 508
Cdd:COG5048 428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
438-750 2.06e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.11  E-value: 2.06e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 513
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 514 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 593
Cdd:COG5048 112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 594 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 673
Cdd:COG5048 189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 674 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 740
Cdd:COG5048 265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                       330
                ....*....|
gi 21542325 741 IHTGEKPYKC 750
Cdd:COG5048 345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
130-508 1.57e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.33  E-value: 1.57e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 130 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKC--EECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQA------- 200
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 201 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 263
Cdd:COG5048 112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 264 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 340
Cdd:COG5048 192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 341 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 407
Cdd:COG5048 268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 408 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 476
Cdd:COG5048 348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                       410       420       430
                ....*....|....*....|....*....|..
gi 21542325 477 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 508
Cdd:COG5048 428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-479 4.15e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.15e-04
                          10        20
                  ....*....|....*....|....*.
gi 21542325   454 NLTEHKKIHTGEKPYKCEECGKAFNR 479
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
147-171 6.09e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 6.09e-04
                          10        20
                  ....*....|....*....|....*
gi 21542325   147 LTKHKRIHTGEKPYKCEECGKAFNQ 171
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
438-750 2.06e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.11  E-value: 2.06e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 513
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 514 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 593
Cdd:COG5048 112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 594 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 673
Cdd:COG5048 189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 674 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 740
Cdd:COG5048 265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                       330
                ....*....|
gi 21542325 741 IHTGEKPYKC 750
Cdd:COG5048 345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
186-655 1.17e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.80  E-value: 1.17e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 186 KPNKCEECGKAFKQASHLTIHKIIHTGEKPY--KYEECGKVFSQSSHLTTQKILHTGENLYKC-KECGKAFNLFSNLTNH 262
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSqcSYSGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 263 KRIHAGEKPYKCKECGrafnISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKltAHKKILMEEKPYKCEECGKVFNQFST 342
Cdd:COG5048 112 SSSSNSNDNNLLSSHS----LPPSSRDPQLPDLLSISNLRNNPLPGNNSSSV--NTPQSNSLHPPLPANSLSKDPSSNLS 185

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 343 LTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFN 422
Cdd:COG5048 186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 423 RSSTLTRHKKIHTGE-------KPYKCEECDRAFSQSSNLTEHK--KIHTGE--KPYKCEE--CGKAFNRFSTLTKHKRI 489
Cdd:COG5048 266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 490 HTGEKPYKCeecgkafnqsyqltrhKIVHTKEKLNKCEEfGKAFKQSSHRTIHKIIHTGEKPYKCEEhgKVFNQSSNLTT 569
Cdd:COG5048 346 HTSISPAKE----------------KLLNSSSKFSPLLN-NEPPQSLQQYKDLKNDKKSETLSNSCI--RNFKRDSNLSL 406

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 570 QKIIHTGENLYKFeehgkafnlfsnitnhkiiytgekphKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSS 649
Cdd:COG5048 407 HIITHLSFRPYNC--------------------------KNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460


                ....*.
gi 21542325 650 TLNRHK 655
Cdd:COG5048 461 LSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
311-761 1.89e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.03  E-value: 1.89e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 311 RSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKC--KECGKAFNQSSNLTEHKKIHTAEKSYKCE- 387
Cdd:COG5048  17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSk 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 388 ECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEkp 467
Cdd:COG5048  97 SLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN-- 174

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 468 ykcEECGKAFNRFSTLTKHKRIHTGEKPYKCEECgkafNQSYQLTRHKIVHTKEklnkceefgkafKQSSHRTIHKIIHT 547
Cdd:COG5048 175 ---SLSKDPSSNLSLLISSNVSTSIPSSSENSPL----SSSYSIPSSSSDQNLE------------NSSSSLPLTTNSQL 235

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 548 GEKPYKCEEHGKVFNQSSNLTTQKiihTGENLYKFEEHGKAFNLFSNITNHKIIYTgekPHKCEECGKAYNRFSNLTIHK 627
Cdd:COG5048 236 SPKSLLSQSPSSLSSSDSSSSASE---SPRSSLPTASSQSSSPNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHL 309

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 628 R--IHTGE--KPYQCAE--CGKAFNCSSTLNRHKIIHTGEKPYKCKEC-------GKAFNLSSTLTAHKKIHTGEKPYKC 694
Cdd:COG5048 310 RsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSET 389

                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21542325 695 E--ECGKAFNQSSNLTTHKKIHTSEKP--YKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSS 761
Cdd:COG5048 390 LsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
130-508 1.57e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.33  E-value: 1.57e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 130 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKC--EECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQA------- 200
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 201 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 263
Cdd:COG5048 112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 264 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 340
Cdd:COG5048 192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 341 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 407
Cdd:COG5048 268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 408 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 476
Cdd:COG5048 348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                       410       420       430
                ....*....|....*....|....*....|..
gi 21542325 477 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 508
Cdd:COG5048 428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
410-779 1.14e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 61.25  E-value: 1.14e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 410 KPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKC--EECDRAFSQSSNLTEHKKIHTGEKPYkcEECGKAFNRFSTLTKHK 487
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSS 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 488 RIHTGEKPYKCE-ECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHgkvFNQSSN 566
Cdd:COG5048 110 LSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDP---SSNLSL 186

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 567 LTTQKIIHTGENLYKFEEHGKaFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 646
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 647 CSSTLNRHKIIHTGE-------KPYKCKECGKAFNLSSTLTAHK--KIHTGE--KPYKCEE--CGKAFNQSSNLTTHKKI 713
Cdd:COG5048 266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 714 HTSEKPYKC--EECGKSFNQFS------SLNIHKIIHT-------------------------------GEKPYKCGDYG 754
Cdd:COG5048 346 HTSISPAKEklLNSSSKFSPLLnneppqSLQQYKDLKNdkksetlsnscirnfkrdsnlslhiithlsfRPYNCKNPPCS 425

                       410       420
                ....*....|....*....|....*
gi 21542325 755 RAFNLSSNLTTHKKIHTGEKPYKCE 779
Cdd:COG5048 426 KSFNRHYNLIPHKKIHTNHAPLLCS 450
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-479 4.15e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.15e-04
                          10        20
                  ....*....|....*....|....*.
gi 21542325   454 NLTEHKKIHTGEKPYKCEECGKAFNR 479
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
483-507 6.09e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 6.09e-04
                          10        20
                  ....*....|....*....|....*
gi 21542325   483 LTKHKRIHTGEKPYKCEECGKAFNQ 507
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
147-171 6.09e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 6.09e-04
                          10        20
                  ....*....|....*....|....*
gi 21542325   147 LTKHKRIHTGEKPYKCEECGKAFNQ 171
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
343-367 8.10e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 8.10e-04
                          10        20
                  ....*....|....*....|....*
gi 21542325   343 LTRHKIIHTGEKPYKCKECGKAFNQ 367
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
651-674 9.38e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 9.38e-04
                          10        20
                  ....*....|....*....|....
gi 21542325   651 LNRHKIIHTGEKPYKCKECGKAFN 674
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
427-451 9.66e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 9.66e-04
                          10        20
                  ....*....|....*....|....*
gi 21542325   427 LTRHKKIHTGEKPYKCEECDRAFSQ 451
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
706-731 1.34e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.34e-03
                          10        20
                  ....*....|....*....|....*.
gi 21542325   706 NLTTHKKIHTSEKPYKCEECGKSFNQ 731
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
622-647 1.46e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.46e-03
                          10        20
                  ....*....|....*....|....*.
gi 21542325   622 NLTIHKRIHTGEKPYQCAECGKAFNC 647
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 352-432 2.13e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.13e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 352 GEKPYKCK--ECGKAFNQSSNLTEHKKiHTaeksykceECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTR 429
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHML-HG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                ...
gi 21542325 430 HKK 432
Cdd:COG5189 417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
679-703 2.79e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.79e-03
                          10        20
                  ....*....|....*....|....*
gi 21542325   679 LTAHKKIHTGEKPYKCEECGKAFNQ 703
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 436-515 3.07e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 3.07e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 436 GEKPYKCE--ECDRAFSQSSNLTEHKKiHTGEKPYKCEECGKafnrfstlTKHKRIHTGEKPYKCEECGKAFNQSYQLTR 513
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                ..
gi 21542325 514 HK 515
Cdd:COG5189 417 HR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 688-739 3.12e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 3.12e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 21542325 688 GEKPYKCE--ECGKAFNQSSNLTTHKK-------------------IHTSEKPYKCEECGKSFNQFSSLNIHK 739
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 408-487 3.29e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 3.29e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 408 GEKPYKCE--ECGKAFNRSSTLTRHKKiHTGEKPYKCEECDRafsqssnlTEHKKIHTGEKPYKCEECGKAFNRFSTLTK 485
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                ..
gi 21542325 486 HK 487
Cdd:COG5189 417 HR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
704-782 3.51e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 3.51e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 704 SSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLS--SNLTTHKKIHTGEKPYKCEYG 781
Cdd:COG5048  18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKS 97


                .
gi 21542325 782 K 782
Cdd:COG5048  98 L 98
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
102-266 6.30e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.68  E-value: 6.30e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 102 KHFKCKECSKSFCVLSQLTQHRR--IHTRVNSYKCEE----CGKAFNWFSTLTKHKRIHTGEKPYKCEecgkafnqssqL 175
Cdd:COG5048 288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGESLKPFSCpyslCGKLFSRNDALKRHILLHTSISPAKEK-----------L 356

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21542325 176 TRHKIIHTEEKPNkceecgkafKQASHLTIHKIIHTGEKPYK-YEECGKVFSQSSHLTTQKILHTGEN--LYKCKECGKA 252
Cdd:COG5048 357 LNSSSKFSPLLNN---------EPPQSLQQYKDLKNDKKSETlSNSCIRNFKRDSNLSLHIITHLSFRpyNCKNPPCSKS 427

                       170
                ....*....|....
gi 21542325 253 FNLFSNLTNHKRIH 266
Cdd:COG5048 428 FNRHYNLIPHKKIH 441
zf-H2C2_2 pfam13465
Zinc-finger double domain;
370-395 6.96e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 6.96e-03
                          10        20
                  ....*....|....*....|....*.
gi 21542325   370 NLTEHKKIHTAEKSYKCEECGKAFNQ 395
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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