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Conserved domains on  [gi|47606223|sp|Q9Y5Q9|]
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RecName: Full=General transcription factor 3C polypeptide 3; AltName: Full=Transcription factor IIIC 102 kDa subunit; Short=TFIIIC 102 kDa subunit; Short=TFIIIC102; AltName: Full=Transcription factor IIIC subunit gamma; Short=TF3C-gamma

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 146-351 8.99e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 96.34  E-value: 8.99e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG2956  73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPsdgeRFMQLARDMAKSYYEAND 305
Cdd:COG2956 153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE-QDP----DYLPALPRLAELYEKLGD 227

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 47606223 306 VTSAINIIDEAFSKHQGLvsmEDVNIAAELYISNKQYDKALEIITD 351
Cdd:COG2956 228 PEEALELLRKALELDPSD---DLLLALADLLERKEGLEAALALLER 270
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 408-514 1.54e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.54e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 408 LLTTLVEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAP 487
Cdd:COG3914 100 LYRRALALNPDN-AEALFNLGNLLLALGRLEEALAALRRAL-ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177

                        90       100
                ....*....|....*....|....*..
gi 47606223 488 LHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYR 204
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 729-842 1.15e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 1.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 729 NPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHmasqkyvLRRHAlivQGFSFLNRYLSLRG 808
Cdd:COG3914 108 NPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR-------LGRLE---EAIAALRRALELDP 177

                        90       100       110
                ....*....|....*....|....*....|....
gi 47606223 809 PCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 146-351 8.99e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 96.34  E-value: 8.99e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG2956  73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPsdgeRFMQLARDMAKSYYEAND 305
Cdd:COG2956 153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE-QDP----DYLPALPRLAELYEKLGD 227

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 47606223 306 VTSAINIIDEAFSKHQGLvsmEDVNIAAELYISNKQYDKALEIITD 351
Cdd:COG2956 228 PEEALELLRKALELDPSD---DLLLALADLLERKEGLEAALALLER 270
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 408-514 1.54e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.54e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 408 LLTTLVEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAP 487
Cdd:COG3914 100 LYRRALALNPDN-AEALFNLGNLLLALGRLEEALAALRRAL-ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177

                        90       100
                ....*....|....*....|....*..
gi 47606223 488 LHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYR 204
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-514 1.78e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   145 LPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLA 224
Cdd:TIGR02917 529 DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLG 608

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   225 EMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLlspsdGERFMQLARDMAKSYYEAN 304
Cdd:TIGR02917 609 RAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALEL-----KPDNTEAQIGLAQLLLAAK 683

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   305 DVTSAINIIDEAFSKHQGlvSMEDVNIAAELYISNKQYDKALeiitdfsgIVLEKKTSEEGTSeenkapenvtctipdgv 384
Cdd:TIGR02917 684 RTESAKKIAKSLQKQHPK--AALGFELEGDLYLRQKDYPAAI--------QAYRKALKRAPSS----------------- 736

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   385 piDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLdVAEAFLDVGEYNSALPLLSALVCSERYNLAVV----WL 460
Cdd:TIGR02917 737 --QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTA-LAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLnnlaWL 813

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 47606223   461 RH-AECLKALGYMERAAEsygkvvdLAPLHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:TIGR02917 814 YLeLKDPRALEYAERALK-------LAPNIPAILDTLGWLLVEKGEADRALPLLR 861
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 201-351 6.84e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 46.34  E-value: 6.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223  201 KSLQFELiaAHLnpsdteeWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNl 280
Cdd:PRK11788 173 DSLRVEI--AHF-------YCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEE- 242

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47606223  281 LSPSdgerFMQLARDMAKSYYEA-NDVTSAINIIDEAFSKHQGLVSMedvNIAAELYISNKQYDKALEIITD 351
Cdd:PRK11788 243 QDPE----YLSEVLPKLMECYQAlGDEAEGLEFLRRALEEYPGADLL---LALAQLLEEQEGPEAAQALLRE 307
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 729-842 1.15e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 1.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 729 NPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHmasqkyvLRRHAlivQGFSFLNRYLSLRG 808
Cdd:COG3914 108 NPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR-------LGRLE---EAIAALRRALELDP 177

                        90       100       110
                ....*....|....*....|....*....|....
gi 47606223 809 PCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 218-293 2.25e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 2.25e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 47606223 218 EEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDG-ERFMQLA 293
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIE-LDPDGGyEKYLYLG 76
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 812-842 2.44e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 2.44e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 47606223    812 ESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
812-840 8.58e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 8.58e-03
                          10        20
                  ....*....|....*....|....*....
gi 47606223   812 ESFYNLGRGLHQLGLIHLAIHYYQKALEL 840
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR_19 pfam14559
Tetratricopeptide repeat;
473-530 9.95e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.25  E-value: 9.95e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   473 ERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALE--PMYDPDTLAQDANAAQ 530
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAalPAADPDDPRYAALLAK 64
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 146-351 8.99e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 96.34  E-value: 8.99e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG2956  73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPsdgeRFMQLARDMAKSYYEAND 305
Cdd:COG2956 153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE-QDP----DYLPALPRLAELYEKLGD 227

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 47606223 306 VTSAINIIDEAFSKHQGLvsmEDVNIAAELYISNKQYDKALEIITD 351
Cdd:COG2956 228 PEEALELLRKALELDPSD---DLLLALADLLERKEGLEAALALLER 270
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-448 8.79e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.62  E-value: 8.79e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 151 GLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQ 230
Cdd:COG2956  10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 231 DNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARDmaksYYEANDVTSAI 310
Cdd:COG2956  90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK-LGPENAHAYCELAEL----YLEQGDYDEAI 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 311 NIIDEAFSKHQGLVsmeDVNIA-AELYISNKQYDKALEIITDFsgivlekktseegtseENKAPENVtctipdgvpiDIT 389
Cdd:COG2956 165 EALEKALKLDPDCA---RALLLlAELYLEQGDYEEAIAALERA----------------LEQDPDYL----------PAL 215

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 47606223 390 VKLMVCLVHLNILEPLNPLLTTLVEQNPEDmgDLYLDVAEAFLDVGEYNSALPLLSALV 448
Cdd:COG2956 216 PRLAELYEKLGDPEEALELLRKALELDPSD--DLLLALADLLERKEGLEAALALLERQL 272
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
156-316 1.09e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 1.09e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 156 ANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQ 235
Cdd:COG0457  15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 236 AIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARdmakSYYEANDVTSAINIIDE 315
Cdd:COG0457  95 ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALE-LDPDDADALYNLGI----ALEKLGRYEEALELLEK 169


                .
gi 47606223 316 A 316
Cdd:COG0457 170 L 170
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 167-297 2.29e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.72  E-value: 2.29e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 167 EAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKY 246
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 47606223 247 EPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMA 297
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 220-514 9.75e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 9.75e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 220 WVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLlSPSDGERFMQLARDmaks 299
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER-DPDRAEALLELAQD---- 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 300 YYEANDVTSAINIIDEAFSKHQGLVSMedVNIAAELYISNKQYDKALEIitdfsgivlekktseegtseenkapenvtct 379
Cdd:COG2956  86 YLKAGLLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEV------------------------------- 132

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 380 ipdgvpiditvklmvclvhlnileplnplLTTLVEQNPEDMgDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVW 459
Cdd:COG2956 133 -----------------------------LERLLKLGPENA-HAYCELAELYLEQGDYDEAIEALEKAL-KLDPDCARAL 181

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 47606223 460 LRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG2956 182 LLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLR 236
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 154-299 1.16e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.56  E-value: 1.16e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 154 GEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNI 233
Cdd:COG3914  83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRL 162

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47606223 234 KQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARDMAKS 299
Cdd:COG3914 163 EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE-LDPDNADAHSNLLFALRQA 227
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
176-347 1.53e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.49  E-value: 1.53e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 176 IRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLW 255
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 256 ERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARdmakSYYEANDVTSAINIIDEAFSKHQGLVsmEDVNIAAEL 335
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALE-LDPDDAEALYNLGL----ALLELGRYDEAIEAYERALELDPDDA--DALYNLGIA 153

                       170
                ....*....|..
gi 47606223 336 YISNKQYDKALE 347
Cdd:COG0457 154 LEKLGRYEEALE 165
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 147-280 4.19e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.44  E-value: 4.19e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 147 RALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQF--ELIAahLNPSDTEEWVRLA 224
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLlhEALE--LDPDEPEARLNLG 79

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 47606223 225 EMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNL 280
Cdd:COG4783  80 LALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
146-279 1.09e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.80  E-value: 1.09e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG0457  39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGL 118

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILN 279
Cdd:COG0457 119 ALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 140-320 3.42e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 3.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 140 RPRSKLPRALRGLMGEANIRFARGEREEAILMCM----EIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
Cdd:COG3914  31 ELEAAALAAALGLALLLLAALAEAAAAALLALAAgeaaAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPD 110

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARd 295
Cdd:COG3914 111 NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE-LDPDNAEALNNLGN- 188

                       170       180
                ....*....|....*....|....*
gi 47606223 296 makSYYEANDVTSAINIIDEAFSKH 320
Cdd:COG3914 189 ---ALQDLGRLEEAIAAYRRALELD 210
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 146-250 1.53e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 1.53e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLmgeANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG4783  38 PEAFALL---GEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                        90       100
                ....*....|....*....|....*
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTN 250
Cdd:COG4783 115 AYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 408-514 1.54e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.54e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 408 LLTTLVEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAP 487
Cdd:COG3914 100 LYRRALALNPDN-AEALFNLGNLLLALGRLEEALAALRRAL-ALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177

                        90       100
                ....*....|....*....|....*..
gi 47606223 488 LHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYR 204
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-514 1.78e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   145 LPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLA 224
Cdd:TIGR02917 529 DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLG 608

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   225 EMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLlspsdGERFMQLARDMAKSYYEAN 304
Cdd:TIGR02917 609 RAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALEL-----KPDNTEAQIGLAQLLLAAK 683

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   305 DVTSAINIIDEAFSKHQGlvSMEDVNIAAELYISNKQYDKALeiitdfsgIVLEKKTSEEGTSeenkapenvtctipdgv 384
Cdd:TIGR02917 684 RTESAKKIAKSLQKQHPK--AALGFELEGDLYLRQKDYPAAI--------QAYRKALKRAPSS----------------- 736

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   385 piDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLdVAEAFLDVGEYNSALPLLSALVCSERYNLAVV----WL 460
Cdd:TIGR02917 737 --QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTA-LAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLnnlaWL 813

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 47606223   461 RH-AECLKALGYMERAAEsygkvvdLAPLHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:TIGR02917 814 YLeLKDPRALEYAERALK-------LAPNIPAILDTLGWLLVEKGEADRALPLLR 861
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 189-320 3.04e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 3.04e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 189 LAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHK 268
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 47606223 269 MAMDGYRRILNlLSPSDGERFMQLARdmakSYYEANDVTSAINIIDEAFSKH 320
Cdd:COG4783  90 EALALLEKALK-LDPEHPEAYLRLAR----AYRALGRPDEAIAALEKALELD 136
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 408-514 3.28e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 3.28e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 408 LLTTLVEQNPEDMgDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAP 487
Cdd:COG4783  26 LLEKALELDPDNP-EAFALLGEILLQLGDLDEAIVLLHEAL-ELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP 103

                        90       100
                ....*....|....*....|....*..
gi 47606223 488 LHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG4783 104 EHPEAYLRLARAYRALGRPDEAIAALE 130
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
192-280 3.79e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 3.79e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 192 IYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFcYTKALKYEPTNVRYLWERSSLYEQMGDHKMAM 271
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                ....*....
gi 47606223 272 DGYRRILNL 280
Cdd:COG3063  80 AYLERALEL 88
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 174-280 4.58e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 4.58e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 174 EIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRY 253
Cdd:COG5010  45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNA 124

                        90       100
                ....*....|....*....|....*..
gi 47606223 254 LWERSSLYEQMGDHKMAMDGYRRILNL 280
Cdd:COG5010 125 YSNLAALLLSLGQDDEAKAALQRALGT 151
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 409-534 4.92e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 4.92e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 409 LTTLVEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNlAVVWLRHAECLKALGYMERAAESYGKVVDLAPL 488
Cdd:COG4235   6 LRQALAANPND-AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN-ADALLDLAEALLAAGDTEEAEELLERALALDPD 83

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 47606223 489 HLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELK 534
Cdd:COG4235  84 NPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIA 129
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
158-252 6.30e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.94  E-value: 6.30e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 158 IRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELiAAHLNPSDTEEWVRLAEMSLEQDNIKQAI 237
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|....*
gi 47606223 238 FCYTKALKYEPTNVR 252
Cdd:COG3063  80 AYLERALELDPSALR 94
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 412-548 2.76e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.23  E-value: 2.76e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 412 LVEQNPEDMGDLYLDVAEAFLDVGEYNSALPLLSALVcsERY-NLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHL 490
Cdd:COG3914  69 AAAAALLLLAALLELAALLLQALGRYEEALALYRRAL--ALNpDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFA 146

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 47606223 491 DARISLSTLQQQLGQPEKALEALEPMydpdtLAQDANAAQqelkLLLHRSTLLFSQGK 548
Cdd:COG3914 147 EAYLNLGEALRRLGRLEEAIAALRRA-----LELDPDNAE----ALNNLGNALQDLGR 195
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 215-347 5.67e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 5.67e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 215 SDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGErfmqLAR 294
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE-LDPDEPE----ARL 76

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 47606223 295 DMAKSYYEANDVTSAINIIDEAFSKHQGlvSMEDVNIAAELYISNKQYDKALE 347
Cdd:COG4783  77 NLGLALLKAGDYDEALALLEKALKLDPE--HPEAYLRLARAYRALGRPDEAIA 127
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
146-281 6.80e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.55  E-value: 6.80e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAE 225
Cdd:COG0457  73 PDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI 152

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 47606223 226 MSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLL 281
Cdd:COG0457 153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 136-248 9.40e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 9.40e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 136 MKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
Cdd:COG5010  41 ELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD 120

                        90       100       110
                ....*....|....*....|....*....|...
gi 47606223 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEP 248
Cdd:COG5010 121 NPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
413-539 1.03e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 1.03e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 413 VEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDA 492
Cdd:COG0457  69 LELDPDD-AEALNNLGLALQALGRYEEALEDYDKAL-ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA 146

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 47606223 493 RISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHR 539
Cdd:COG0457 147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 185-515 3.24e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   185 PFSTLAMIYEDQGDMEKS-LQFELiAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQ 263
Cdd:TIGR02917 467 LHNLLGAIYLGKGDLAKArEAFEK-ALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLR 545

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   264 MGDHKMAMDGYRRiLNLLSPSDGERFMQLARdmakSYYEANDVTSAINIIDEAFSKHQGlvSMEDVNIAAELYISNKQYD 343
Cdd:TIGR02917 546 TGNEEEAVAWLEK-AAELNPQEIEPALALAQ----YYLGKGQLKKALAILNEAADAAPD--SPEAWLMLGRAQLAAGDLN 618

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   344 KALEIITDFSGIV--------------LEKKTSEEGTSEENKAPENVtctiPDGVpiDITVKLMVCLVHLNILEPLNPLL 409
Cdd:TIGR02917 619 KAVSSFKKLLALQpdsalalllladayAVMKNYAKAITSLKRALELK----PDNT--EAQIGLAQLLLAAKRTESAKKIA 692

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   410 TTLVEQNPED------MGDLYLDVAEAFLDVGEYNSALP----------LLSALVCSERYNLAV----VWLR----HAEC 465
Cdd:TIGR02917 693 KSLQKQHPKAalgfelEGDLYLRQKDYPAAIQAYRKALKrapssqnaikLHRALLASGNTAEAVktleAWLKthpnDAVL 772

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47606223   466 LKALG--YMER-----AAESYGKVVDLAPLHLDARISLSTLQQQLGQP------EKALEaLEP 515
Cdd:TIGR02917 773 RTALAelYLAQkdydkAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPraleyaERALK-LAP 834
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 146-245 4.63e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 4.63e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEeWVRLAE 225
Cdd:COG2956 175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALAD 253

                        90       100
                ....*....|....*....|
gi 47606223 226 MSLEQDNIKQAIFCYTKALK 245
Cdd:COG2956 254 LLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
413-514 1.25e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.69  E-value: 1.25e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 413 VEQNPEDmGDLYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDA 492
Cdd:COG0457  35 LELDPDD-AEALYNLGLAYLRLGRYEEALADYEQAL-ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEA 112

                        90       100
                ....*....|....*....|..
gi 47606223 493 RISLSTLQQQLGQPEKALEALE 514
Cdd:COG0457 113 LYNLGLALLELGRYDEAIEAYE 134
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
228-316 3.21e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 3.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 228 LEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDgYRRILNlLSPSDGERFMQLARdmakSYYEANDVT 307
Cdd:COG3063   3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK-LDPNNAEALLNLAE----LLLELGDYD 76


                ....*....
gi 47606223 308 SAINIIDEA 316
Cdd:COG3063  77 EALAYLERA 85
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 173-316 3.55e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 3.55e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 173 MEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVR 252
Cdd:COG5010  10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE 89

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47606223 253 YLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARdmakSYYEANDVTSAINIIDEA 316
Cdd:COG5010  90 LYYNLALLYSRSGDKDEAKEYYEKALA-LSPDNPNAYSNLAA----LLLSLGQDDEAKAALQRA 148
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 430-536 4.29e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.44  E-value: 4.29e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 430 AFLDVGEYNSALPLLSALVcsERY----NLAVVWLRHAECLKALGYMERAAESYGKVVDLAP---LHLDARISLSTLQQQ 502
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFL--KRYpnspLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPdspKAPDALLKLGLSYLE 79

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 47606223 503 LGQPEKALEALEPMYD--PDTLAqdANAAQQELKLL 536
Cdd:COG1729  80 LGDYDKARATLEELIKkyPDSEA--AKEARARLARL 113
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
209-347 6.52e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 6.52e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 209 AAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGER 288
Cdd:COG4785  65 RALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALE-LDPDYAYA 143

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47606223 289 FMQLARdmakSYYEANDVTSAINIIDEAFSKHQglvsmEDVNIAAELYISNKQ--YDKALE 347
Cdd:COG4785 144 YLNRGI----ALYYLGRYELAIADLEKALELDP-----NDPERALWLYLAERKldPEKALA 195
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 201-351 6.84e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 46.34  E-value: 6.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223  201 KSLQFELiaAHLnpsdteeWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNl 280
Cdd:PRK11788 173 DSLRVEI--AHF-------YCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEE- 242

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47606223  281 LSPSdgerFMQLARDMAKSYYEA-NDVTSAINIIDEAFSKHQGLVSMedvNIAAELYISNKQYDKALEIITD 351
Cdd:PRK11788 243 QDPE----YLSEVLPKLMECYQAlGDEAEGLEFLRRALEEYPGADLL---LALAQLLEEQEGPEAAQALLRE 307
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 136-548 9.49e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 9.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   136 MKEKRPRSKLPRALRGLmgeanIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQ-FELIAAHLnP 214
Cdd:TIGR02917 253 LLKKAPNSPLAHYLKAL-----VDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQyLNQILKYA-P 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   215 SDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRIlNLLSPSDGERFMQLar 294
Cdd:TIGR02917 327 NSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKA-TELDPENAAARTQL-- 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   295 dmAKSYYEANDVTSAINIIDEAfskhqglVSMEDVNIAAEL-----YISNKQYDKALEIITDF--------------SGI 355
Cdd:TIGR02917 404 --GISKLSQGDPSEAIADLETA-------AQLDPELGRADLllilsYLRSGQFDKALAAAKKLekkqpdnaslhnllGAI 474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   356 VLEKKTSEEGTSEENKA----PENVTCTIpdgvpiditvklmvclvhlnileplNPLLTTLVEQNPEDMGDLYLDVaeaf 431
Cdd:TIGR02917 475 YLGKGDLAKAREAFEKAlsiePDFFPAAA-------------------------NLARIDIQEGNPDDAIQRFEKV---- 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   432 ldVGEYNSALPLLSAlvcserynLAVVWLRHAECLKALGYMERAAESYGKvvDLAPlhldaRISLSTLQQQLGQPEKALE 511
Cdd:TIGR02917 526 --LTIDPKNLRAILA--------LAGLYLRTGNEEEAVAWLEKAAELNPQ--EIEP-----ALALAQYYLGKGQLKKALA 588

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 47606223   512 ALEPmydpdtlAQDANAAQQELKLLLHRSTLLFSQGK 548
Cdd:TIGR02917 589 ILNE-------AADAAPDSPEAWLMLGRAQLAAGDLN 618
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 144-347 3.55e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 3.55e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 144 KLPRALRGLMGEANIRFARGEREEAILMcmeIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRL 223
Cdd:COG3914   8 ALAALAAAALLAAAAAAELALAAELEAA---ALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 224 AEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDGERFMQLARdmakSYYEA 303
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALA-LNPDFAEAYLNLGE----ALRRL 159

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 47606223 304 NDVTSAINIIDEAFSKHQGLVSMeDVNIAAeLYISNKQYDKALE 347
Cdd:COG3914 160 GRLEEAIAALRRALELDPDNAEA-LNNLGN-ALQDLGRLEEAIA 201
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
454-514 1.04e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.92  E-value: 1.04e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47606223 454 NLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYE 66
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 729-842 1.15e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 1.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 729 NPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHmasqkyvLRRHAlivQGFSFLNRYLSLRG 808
Cdd:COG3914 108 NPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR-------LGRLE---EAIAALRRALELDP 177

                        90       100       110
                ....*....|....*....|....*....|....
gi 47606223 809 PCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 423-523 1.73e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 1.73e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 423 LYLDVAEAFLDVGEYNSALPLLSALVcSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQ 502
Cdd:COG5010  56 IESPSDNLYNKLGDFEESLALLEQAL-QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLS 134

                        90       100
                ....*....|....*....|.
gi 47606223 503 LGQPEKALEALEPMYDPDTLA 523
Cdd:COG5010 135 LGQDDEAKAALQRALGTSPLK 155
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 218-293 2.25e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 2.25e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 47606223 218 EEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNlLSPSDG-ERFMQLA 293
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIE-LDPDGGyEKYLYLG 76
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 812-842 2.44e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 2.44e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 47606223    812 ESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDP 32
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 720-842 2.69e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 2.69e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 720 RFCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLtfIHMASQKYVlrrhalivQGFSF 799
Cdd:COG4783  25 ALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL--ALLKAGDYD--------EALAL 94

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 47606223 800 LNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPP 842
Cdd:COG4783  95 LEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 422-514 4.41e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 4.41e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 422 DLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQ 501
Cdd:COG5010  20 LRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYS 99

                        90
                ....*....|...
gi 47606223 502 QLGQPEKALEALE 514
Cdd:COG5010 100 RSGDKDEAKEYYE 112
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 456-514 7.17e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 7.17e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 47606223 456 AVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALE 514
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLH 62
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 144-282 8.01e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.51  E-value: 8.01e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 144 KLPRALRgLMGEANIRFAR-----GEREEAilmcMEIIRQApLAYEPFSTLAMIYEDQGDMEKSLQFELI--AAHLNPSD 216
Cdd:COG3071 184 ALPRAER-RDPELAAAYARalialGDHDEA----ERLLREA-LKRQWDPRLVRLYGRLQGGDPAKQLKRAekWLKKHPND 257

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47606223 217 TEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWErSSLYEQMGDHKMAMDGYRRILNLLS 282
Cdd:COG3071 258 PDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAEL-ARLLEQLGDPEEAAEHYRKALALAL 322
TPR_1 pfam00515
Tetratricopeptide repeat;
812-840 8.58e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 8.58e-03
                          10        20
                  ....*....|....*....|....*....
gi 47606223   812 ESFYNLGRGLHQLGLIHLAIHYYQKALEL 840
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 146-226 9.17e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.29  E-value: 9.17e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223 146 PRALRGLmgeANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDtEEWVRLAE 225
Cdd:COG4235  51 ADALLDL---AEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD-APARLLEA 126


                .
gi 47606223 226 M 226
Cdd:COG4235 127 S 127
TPR_19 pfam14559
Tetratricopeptide repeat;
473-530 9.95e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.25  E-value: 9.95e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47606223   473 ERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALE--PMYDPDTLAQDANAAQ 530
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAalPAADPDDPRYAALLAK 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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