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Conserved domains on  [gi|1624818111|gb|QCF58630|]
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myristylated tegument protein [human gammaherpesvirus 4]

Protein Classification

PHA03358 family protein( domain architecture ID 10010536)

PHA03358 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03358 PHA03358
Alkaline exonuclease; Provisional
 1-75 4.01e-41

Alkaline exonuclease; Provisional


:

Pssm-ID: 177596  Cd Length: 75  Bit Score: 128.89  E-value: 4.01e-41
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1624818111  1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFNLETTKLIAVEEGRACGETNEGLEYDEDSENDELLFLPNKKPN 75
Cdd:PHA03358   1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFSLETTKLIAAEEGRACGETNEGLEYDDDSENDELLFLPNKKPN 75
 
Name Accession Description Interval E-value
PHA03358 PHA03358
Alkaline exonuclease; Provisional
 1-75 4.01e-41

Alkaline exonuclease; Provisional


Pssm-ID: 177596  Cd Length: 75  Bit Score: 128.89  E-value: 4.01e-41
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1624818111  1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFNLETTKLIAVEEGRACGETNEGLEYDEDSENDELLFLPNKKPN 75
Cdd:PHA03358   1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFSLETTKLIAAEEGRACGETNEGLEYDDDSENDELLFLPNKKPN 75
Herpesvir_UL11 pfam10813
Herpesvirus UL11 homolog; This entry contains viral proteins that are involved in virion ...
 1-32 6.18e-15

Herpesvirus UL11 homolog; This entry contains viral proteins that are involved in virion envelopment and egress. It includes Epstein-Barr virus (EBV) BBLF1 protein (also known as cytoplasmic envelopment protein 3), which is present in the tegument layer of EBV and is involved in virion maturation. BBLF1 also participates in viral entry at the fusion step probably by regulating the core fusion machinery. BBLF1 has been shown to localize to the trans-Golgi network along with gp350/220, a site where final envelopment of EBV particles takes place. BBLF1 shares 13 to 15% amino acid sequence identity with the herpes simplex virus 1 UL11 and cytomegalovirus UL99 tegument proteins, and like these it is a myristoylated and palmitoylated protein.


Pssm-ID: 287750  Cd Length: 32  Bit Score: 61.64  E-value: 6.18e-15
                         10        20        30
                 ....*....|....*....|....*....|..
gi 1624818111  1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEF 32
Cdd:pfam10813  1 MGFLLSICKRRSNPVKDVDGEPINVVEDFEEF 32
 
Name Accession Description Interval E-value
PHA03358 PHA03358
Alkaline exonuclease; Provisional
 1-75 4.01e-41

Alkaline exonuclease; Provisional


Pssm-ID: 177596  Cd Length: 75  Bit Score: 128.89  E-value: 4.01e-41
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1624818111  1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFNLETTKLIAVEEGRACGETNEGLEYDEDSENDELLFLPNKKPN 75
Cdd:PHA03358   1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFSLETTKLIAAEEGRACGETNEGLEYDDDSENDELLFLPNKKPN 75
Herpesvir_UL11 pfam10813
Herpesvirus UL11 homolog; This entry contains viral proteins that are involved in virion ...
 1-32 6.18e-15

Herpesvirus UL11 homolog; This entry contains viral proteins that are involved in virion envelopment and egress. It includes Epstein-Barr virus (EBV) BBLF1 protein (also known as cytoplasmic envelopment protein 3), which is present in the tegument layer of EBV and is involved in virion maturation. BBLF1 also participates in viral entry at the fusion step probably by regulating the core fusion machinery. BBLF1 has been shown to localize to the trans-Golgi network along with gp350/220, a site where final envelopment of EBV particles takes place. BBLF1 shares 13 to 15% amino acid sequence identity with the herpes simplex virus 1 UL11 and cytomegalovirus UL99 tegument proteins, and like these it is a myristoylated and palmitoylated protein.


Pssm-ID: 287750  Cd Length: 32  Bit Score: 61.64  E-value: 6.18e-15
                         10        20        30
                 ....*....|....*....|....*....|..
gi 1624818111  1 MGALWSLCRRRVNSIGDVDGGIINLYNDYEEF 32
Cdd:pfam10813  1 MGFLLSICKRRSNPVKDVDGEPINVVEDFEEF 32
PHA03149 PHA03149
hypothetical protein; Provisional
 1-55 4.57e-07

hypothetical protein; Provisional


Pssm-ID: 165420  Cd Length: 66  Bit Score: 42.33  E-value: 4.57e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1624818111  1 MGALWSLCRRRVNSIgDVDGGIINLYNDYEEFNLETTKLIAVEEGRACGETNEGL 55
Cdd:PHA03149   1 MGTLCSICKRRPNPL-DTEGKVINLPDDFEELSETEIMLACPHDKKLCKKNKESM 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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