|
Name |
Accession |
Description |
Interval |
E-value |
| ND2 |
MTH00160 |
NADH dehydrogenase subunit 2; Provisional |
1-336 |
7.60e-48 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214442 [Multi-domain] Cd Length: 335 Bit Score: 163.84 E-value: 7.60e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 1 MNLMKILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMILTKF 80
Cdd:MTH00160 3 MNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 81 SMNwekSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFsLMVVILSITIGA 160
Cdd:MTH00160 83 MLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFI-IIIIILSAIIGA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 161 MGGLNQTS************************************************************************ 240
Cdd:MTH00160 159 IGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 241 ********-****************************VLTCITLYYYLRLSFSSIVLTNNELSWSTDIKMWKFKMIVPIT 319
Cdd:MTH00160 239 NLLSLGGLpPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFL 318
|
330
....*....|....*..
gi 1707765489 320 VMISSLGLMFSTSLTSY 336
Cdd:MTH00160 319 SFISLFGLILSSLLFLL 335
|
|
| Proton_antipo_M |
pfam00361 |
Proton-conducting membrane transporter; This is a family of membrane transporters that ... |
22-168 |
1.46e-10 |
|
Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.
Pssm-ID: 425636 [Multi-domain] Cd Length: 291 Bit Score: 61.18 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 22 SNSWFGVWMGLEINLLSFIPLM-VNDKNLMINESSIKYFIVQAMASTMLLFSILMILT--------------KFSMNWEK 86
Cdd:pfam00361 1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNytgtlsfdelskalTGGLNSSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 87 SMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMN-CFILMTWQKIAPMLVM-------SYCISTNLFSLMVVILSITI 158
Cdd:pfam00361 81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160
|
170
....*....|
gi 1707765489 159 GAMGGLNQTS 168
Cdd:pfam00361 161 GSLAALVQTD 170
|
|
| NuoN |
COG1007 |
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ... |
6-114 |
4.61e-05 |
|
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase
Pssm-ID: 440631 [Multi-domain] Cd Length: 473 Bit Score: 44.72 E-value: 4.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMmGSFISISSNSWFGVWMGLEinLLSfIPLMV----NDKNLMINESSIKYFIVQAMASTMLLFSILM------ 75
Cdd:COG1007 106 ALLLFATL-GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatg 181
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1707765489 76 ------ILTKFSMNWEKS---MISSMMINSSLLIKIGATPFHFWFPEV 114
Cdd:COG1007 182 slnlagIAAALAAGGANSpllLLGLVLVLAGLAFKLSAVPFHMWTPDV 229
|
|
| NDH_I_N |
TIGR01770 |
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ... |
6-168 |
4.72e-04 |
|
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]
Pssm-ID: 273795 [Multi-domain] Cd Length: 468 Bit Score: 41.86 E-value: 4.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMmGSFISISSNSWFGVWMGLEINLLSFIPLM-VNDKNLMINESSIKYFIVQAMASTMLLFSILMI-------- 76
Cdd:TIGR01770 106 ILLLFALL-GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgsln 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 77 ---LTKFSMNWEKS----MISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAP----MLVMSYCIST- 144
Cdd:TIGR01770 185 fedLLLFLSNGMLNisllLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGf 264
|
170 180
....*....|....*....|....*...
gi 1707765489 145 ----NLFSLMVVILSITIGAMGGLNQTS 168
Cdd:TIGR01770 265 seawQIFLAIIAFLSMLIGNFGALAQKK 292
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| ND2 |
MTH00160 |
NADH dehydrogenase subunit 2; Provisional |
1-336 |
7.60e-48 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214442 [Multi-domain] Cd Length: 335 Bit Score: 163.84 E-value: 7.60e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 1 MNLMKILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMILTKF 80
Cdd:MTH00160 3 MNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 81 SMNwekSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFsLMVVILSITIGA 160
Cdd:MTH00160 83 MLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFI-IIIIILSAIIGA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 161 MGGLNQTS************************************************************************ 240
Cdd:MTH00160 159 IGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 241 ********-****************************VLTCITLYYYLRLSFSSIVLTNNELSWSTDIKMWKFKMIVPIT 319
Cdd:MTH00160 239 NLLSLGGLpPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFL 318
|
330
....*....|....*..
gi 1707765489 320 VMISSLGLMFSTSLTSY 336
Cdd:MTH00160 319 SFISLFGLILSSLLFLL 335
|
|
| ND2 |
MTH00112 |
NADH dehydrogenase subunit 2; Provisional |
1-167 |
1.74e-32 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214423 [Multi-domain] Cd Length: 346 Bit Score: 123.78 E-value: 1.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 1 MNLM-KILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSIlMILTK 79
Cdd:MTH00112 1 MNPHaKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAW 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 80 FSMNWEKSM----ISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPM---LVMSYCISTNLFSLMvV 152
Cdd:MTH00112 80 NTGQWDITQltnpTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLtllLMTSNSLNPTLLLTL-A 158
|
170
....*....|....*
gi 1707765489 153 ILSITIGAMGGLNQT 167
Cdd:MTH00112 159 ILSTLIGGWGGLNQT 173
|
|
| ND2 |
MTH00105 |
NADH dehydrogenase subunit 2; Provisional |
6-167 |
1.97e-30 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177167 [Multi-domain] Cd Length: 347 Bit Score: 118.02 E-value: 1.97e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSI---LMILTKFSM 82
Cdd:MTH00105 7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIiinLMYSGQWTI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 83 NWEKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVM---SYCISTNLFsLMVVILSITIG 159
Cdd:MTH00105 87 TKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINPNLL-LTLAILSILIG 165
|
....*...
gi 1707765489 160 AMGGLNQT 167
Cdd:MTH00105 166 GWGGLNQT 173
|
|
| ND2 |
MTH00041 |
NADH dehydrogenase subunit 2; Validated |
6-168 |
4.55e-30 |
|
NADH dehydrogenase subunit 2; Validated
Pssm-ID: 177116 [Multi-domain] Cd Length: 349 Bit Score: 117.34 E-value: 4.55e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSIL---MILTKFSM 82
Cdd:MTH00041 7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALiqaWLSGSWSI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 83 NWEKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVV--ILSITIGA 160
Cdd:MTH00041 87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILcgILSVLVGG 166
|
....*...
gi 1707765489 161 MGGLNQTS 168
Cdd:MTH00041 167 WGGLNQTQ 174
|
|
| ND2 |
MTH00070 |
NADH dehydrogenase subunit 2; Provisional |
8-167 |
7.88e-29 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177142 [Multi-domain] Cd Length: 346 Bit Score: 113.86 E-value: 7.88e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 8 FLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILM---ILTKFSMNW 84
Cdd:MTH00070 9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 85 EKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPM---LVMSYCISTNLFSLMvVILSITIGAM 161
Cdd:MTH00070 89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMallIQISHLLNSNLLIIM-GLLSTLIGGW 167
|
....*.
gi 1707765489 162 GGLNQT 167
Cdd:MTH00070 168 GGLNQT 173
|
|
| ND2 |
MTH00144 |
NADH dehydrogenase subunit 2; Provisional |
1-168 |
1.52e-26 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214432 [Multi-domain] Cd Length: 328 Bit Score: 107.28 E-value: 1.52e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 1 MNLMKILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMiltkf 80
Cdd:MTH00144 2 SSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLI----- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 81 SMNWEKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVVILSI---T 157
Cdd:MTH00144 77 MYNLSFSWFSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVlsaL 156
|
170
....*....|.
gi 1707765489 158 IGAMGGLNQTS 168
Cdd:MTH00144 157 VGSIGGLNQTQ 167
|
|
| ND2 |
MTH00135 |
NADH dehydrogenase subunit 2; Provisional |
7-167 |
4.94e-25 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177193 [Multi-domain] Cd Length: 347 Bit Score: 103.35 E-value: 4.94e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 7 LFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILM---ILTKFSMN 83
Cdd:MTH00135 8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTnawLTGQWDIQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 84 WEKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMsYCISTNLFSLMVV--ILSITIGAM 161
Cdd:MTH00135 88 QMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALI-LQIAPTNPTLLITlgLTSTLVGGW 166
|
....*.
gi 1707765489 162 GGLNQT 167
Cdd:MTH00135 167 GGLNQT 172
|
|
| ND2 |
MTH00197 |
NADH dehydrogenase subunit 2; Provisional |
7-168 |
4.22e-23 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177244 [Multi-domain] Cd Length: 323 Bit Score: 97.44 E-value: 4.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 7 LFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMILtkfsMNWEK 86
Cdd:MTH00197 2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF----SNLYL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 87 SMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVVILSITIGAMGGLNQ 166
Cdd:MTH00197 78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157
|
..
gi 1707765489 167 TS 168
Cdd:MTH00197 158 SN 159
|
|
| ND2 |
MTH00011 |
NADH dehydrogenase subunit 2; Validated |
7-167 |
3.61e-22 |
|
NADH dehydrogenase subunit 2; Validated
Pssm-ID: 164587 [Multi-domain] Cd Length: 330 Bit Score: 95.23 E-value: 3.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 7 LFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMILTKFSMnweK 86
Cdd:MTH00011 10 LFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL---L 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 87 SMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVVI--LSITIGAMGGL 164
Cdd:MTH00011 87 KNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMaaMSALAGGLGGM 166
|
...
gi 1707765489 165 NQT 167
Cdd:MTH00011 167 NQT 169
|
|
| ND2 |
MTH00200 |
NADH dehydrogenase subunit 2; Provisional |
3-167 |
6.85e-22 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177246 [Multi-domain] Cd Length: 347 Bit Score: 94.65 E-value: 6.85e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 3 LMKILFLSSLMMGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMILT---K 79
Cdd:MTH00200 4 LILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWtsgQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 80 FSMNWEKSMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAP--MLVMSYCISTNLFSLMVVILSIT 157
Cdd:MTH00200 84 WGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPfaLLIQLAPALNSNILLLLGLLSVL 163
|
170
....*....|
gi 1707765489 158 IGAMGGLNQT 167
Cdd:MTH00200 164 VGGWGGLNQT 173
|
|
| Proton_antipo_M |
pfam00361 |
Proton-conducting membrane transporter; This is a family of membrane transporters that ... |
22-168 |
1.46e-10 |
|
Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.
Pssm-ID: 425636 [Multi-domain] Cd Length: 291 Bit Score: 61.18 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 22 SNSWFGVWMGLEINLLSFIPLM-VNDKNLMINESSIKYFIVQAMASTMLLFSILMILT--------------KFSMNWEK 86
Cdd:pfam00361 1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNytgtlsfdelskalTGGLNSSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 87 SMISSMMINSSLLIKIGATPFHFWFPEVMKASSWMN-CFILMTWQKIAPMLVM-------SYCISTNLFSLMVVILSITI 158
Cdd:pfam00361 81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160
|
170
....*....|
gi 1707765489 159 GAMGGLNQTS 168
Cdd:pfam00361 161 GSLAALVQTD 170
|
|
| ND2 |
MTH00196 |
NADH dehydrogenase subunit 2; Provisional |
14-167 |
8.27e-10 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214453 [Multi-domain] Cd Length: 365 Bit Score: 59.27 E-value: 8.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 14 MGSFISISSNSWFGVWMGLEINLLSFIPLMVNDKN-LMINESSIKYFIVQAMASTMLLFSILMI----------LTKFSM 82
Cdd:MTH00196 4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGsGYSAEAGLKYFVLGALSSGLFLFGCALLcgttgglhlsYINLVL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 83 NWEKSM------ISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVVILSI 156
Cdd:MTH00196 84 NSGQSFssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163
|
170
....*....|.
gi 1707765489 157 TIGAMGGLNQT 167
Cdd:MTH00196 164 FVGAIGALNQT 174
|
|
| ND2 |
MTH00199 |
NADH dehydrogenase subunit 2; Provisional |
14-168 |
2.68e-09 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 177245 [Multi-domain] Cd Length: 460 Bit Score: 58.10 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 14 MGSFISISSNSWFGVWMGLEINLLS-FIPLMVNDKNLMINESSIKYFIVQAMASTMLLF------------SILMILTKF 80
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFgcallygltgetSIQGINSIL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 81 SMNWEKSMISSmminsSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLFSLMVVILSITIGA 160
Cdd:MTH00199 188 TGDVGKILITI-----SLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGA 262
|
....*...
gi 1707765489 161 MGGLNQTS 168
Cdd:MTH00199 263 IGALNQTK 270
|
|
| ND2 |
MTH00198 |
NADH dehydrogenase subunit 2; Provisional |
14-167 |
1.72e-06 |
|
NADH dehydrogenase subunit 2; Provisional
Pssm-ID: 214454 [Multi-domain] Cd Length: 607 Bit Score: 49.47 E-value: 1.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 14 MGSFISISSNSWFGVWMGLEINLLSFIPL---------MVNDKNLMINESSIKYFIVQAMASTMLLFSIL---------- 74
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFGCAlyfgftgneg 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 75 MILTKFSMNWEKSMIS-------SMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAPMLVMSYCISTNLF 147
Cdd:MTH00198 279 MLGTILSATLETTNIElrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358
|
170 180
....*....|....*....|
gi 1707765489 148 SLMVVILSITIGAMGGLNQT 167
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQT 378
|
|
| PRK05777 |
PRK05777 |
NADH-quinone oxidoreductase subunit NuoN; |
6-114 |
1.91e-05 |
|
NADH-quinone oxidoreductase subunit NuoN;
Pssm-ID: 235603 [Multi-domain] Cd Length: 476 Bit Score: 45.97 E-value: 1.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMmGSFISISSNSWFGVWMGLEI-NLLSFIPLMVNDKNLMINESSIKYFIVQAMASTMLLFSILMI-------- 76
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgsls 185
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1707765489 77 LTKFSMNWEKSMISSM-------MINSSLLIKIGATPFHFWFPEV 114
Cdd:PRK05777 186 FAGIAKALADGSGNSLlllfglvFLLVGLAFKLSAVPFHMWTPDV 230
|
|
| NuoN |
COG1007 |
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ... |
6-114 |
4.61e-05 |
|
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase
Pssm-ID: 440631 [Multi-domain] Cd Length: 473 Bit Score: 44.72 E-value: 4.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMmGSFISISSNSWFGVWMGLEinLLSfIPLMV----NDKNLMINESSIKYFIVQAMASTMLLFSILM------ 75
Cdd:COG1007 106 ALLLFATL-GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatg 181
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1707765489 76 ------ILTKFSMNWEKS---MISSMMINSSLLIKIGATPFHFWFPEV 114
Cdd:COG1007 182 slnlagIAAALAAGGANSpllLLGLVLVLAGLAFKLSAVPFHMWTPDV 229
|
|
| NDH_I_N |
TIGR01770 |
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ... |
6-168 |
4.72e-04 |
|
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]
Pssm-ID: 273795 [Multi-domain] Cd Length: 468 Bit Score: 41.86 E-value: 4.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 6 ILFLSSLMmGSFISISSNSWFGVWMGLEINLLSFIPLM-VNDKNLMINESSIKYFIVQAMASTMLLFSILMI-------- 76
Cdd:TIGR01770 106 ILLLFALL-GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgsln 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707765489 77 ---LTKFSMNWEKS----MISSMMINSSLLIKIGATPFHFWFPEVMKASSWMNCFILMTWQKIAP----MLVMSYCIST- 144
Cdd:TIGR01770 185 fedLLLFLSNGMLNisllLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGf 264
|
170 180
....*....|....*....|....*...
gi 1707765489 145 ----NLFSLMVVILSITIGAMGGLNQTS 168
Cdd:TIGR01770 265 seawQIFLAIIAFLSMLIGNFGALAQKK 292
|
|
|