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Conserved domains on  [gi|1722559445|gb|QED43057|]
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TGB3 [Asparagus virus 3]

Protein Classification

movement TGBp3 family protein( domain architecture ID 10494730)

movement TGBp3 family protein similar to Tymovirales movement protein TGBp3 (triple gene block protein 3) that plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TGBp3 pfam02495
Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple ...
23-77 8.71e-10

Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple gene block 3 proteins (TGBp3) are involved in virus momvement. TGBp3 is an integral ER membrane protein with a single transmembrane domain, and a C-terminal region exposed to the cytosol. TGBp3 is able to target TGBp2 to the cortical ER tubules of the cell periphery through the sorting signal in the C-terminal region of TGBp3. Moreover, it plays a key role in virus cell-to-cell movement by enhancing the TGBp2- and TGBp3-dependent plasmodesmata (PD) localization of TGBp1; however, the enhancement is abolished when one of the two conserved Cys residues in the C-terminal region of TGBp3 is replaced with Ala.


:

Pssm-ID: 396861  Cd Length: 59  Bit Score: 49.19  E-value: 8.71e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1722559445 23 LNGLLALSVALCMFALIVPKPQPCLVIITGESVSISGCPDPSLILAHL-NLAPWNG 77
Cdd:pfam02495  4 LALIGLLLFLLALYLLNTPSSEGCTIVITGESVTITGCEFTPEFIEAVkGLKPLNH 59
 
Name Accession Description Interval E-value
TGBp3 pfam02495
Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple ...
23-77 8.71e-10

Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple gene block 3 proteins (TGBp3) are involved in virus momvement. TGBp3 is an integral ER membrane protein with a single transmembrane domain, and a C-terminal region exposed to the cytosol. TGBp3 is able to target TGBp2 to the cortical ER tubules of the cell periphery through the sorting signal in the C-terminal region of TGBp3. Moreover, it plays a key role in virus cell-to-cell movement by enhancing the TGBp2- and TGBp3-dependent plasmodesmata (PD) localization of TGBp1; however, the enhancement is abolished when one of the two conserved Cys residues in the C-terminal region of TGBp3 is replaced with Ala.


Pssm-ID: 396861  Cd Length: 59  Bit Score: 49.19  E-value: 8.71e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1722559445 23 LNGLLALSVALCMFALIVPKPQPCLVIITGESVSISGCPDPSLILAHL-NLAPWNG 77
Cdd:pfam02495  4 LALIGLLLFLLALYLLNTPSSEGCTIVITGESVTITGCEFTPEFIEAVkGLKPLNH 59
 
Name Accession Description Interval E-value
TGBp3 pfam02495
Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple ...
23-77 8.71e-10

Triple gene block 3; Family members include TGBp3 proteins found in many plant viruses. Triple gene block 3 proteins (TGBp3) are involved in virus momvement. TGBp3 is an integral ER membrane protein with a single transmembrane domain, and a C-terminal region exposed to the cytosol. TGBp3 is able to target TGBp2 to the cortical ER tubules of the cell periphery through the sorting signal in the C-terminal region of TGBp3. Moreover, it plays a key role in virus cell-to-cell movement by enhancing the TGBp2- and TGBp3-dependent plasmodesmata (PD) localization of TGBp1; however, the enhancement is abolished when one of the two conserved Cys residues in the C-terminal region of TGBp3 is replaced with Ala.


Pssm-ID: 396861  Cd Length: 59  Bit Score: 49.19  E-value: 8.71e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1722559445 23 LNGLLALSVALCMFALIVPKPQPCLVIITGESVSISGCPDPSLILAHL-NLAPWNG 77
Cdd:pfam02495  4 LALIGLLLFLLALYLLNTPSSEGCTIVITGESVTITGCEFTPEFIEAVkGLKPLNH 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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