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Conserved domains on  [gi|1723414515|gb|QED89927|]
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acyl transferase luxD [Cloning vector pBAC_Fission]

Protein Classification

alpha/beta hydrolase; lipase family alpha/beta hydrolase( domain architecture ID 10014291)

uncharacterized alpha/beta hydrolase; may catalyze the cleavage and formation of ester bonds; lipase family alpha/beta hydrolase similar to triacylglycerol lipase that catalyzes the hydrolysis of triacylglycerol

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
luxD PRK13604
acyl transferase; Provisional
1-307 0e+00

acyl transferase; Provisional


:

Pssm-ID: 184175  Cd Length: 307  Bit Score: 588.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515   1 MENESKYKTIDHVICVEGNKKIHVWETLPEENSPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHVGLSS 80
Cdd:PRK13604    1 MKNESSFKTIDHVICLENGQSIRVWETLPKENSPKKNNTILIASGFARRMDHFAGLAEYLSSNGFHVIRYDSLHHVGLSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  81 GTIDEFTMSIGKQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASFLITAVGVVNLRYSLERALGFDYLSLPI 160
Cdd:PRK13604   81 GTIDEFTMSIGKNSLLTVVDWLNTRGINNLGLIAASLSARIAYEVINEIDLSFLITAVGVVNLRDTLERALGYDYLSLPI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 161 NELPDNLDFEGHKLGAEVFARDCLDFGWEDLASTINNMMYLDIPFIAFTANNDNWVKQDEVITLLSNIRSNRCKIYSLLG 240
Cdd:PRK13604  161 DELPEDLDFEGHNLGSEVFVTDCFKHGWDTLDSTINKMKGLDIPFIAFTANNDSWVKQSEVIDLLDSIRSEQCKLYSLIG 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1723414515 241 SSHDLSENLVVLRNFYQSVTKAAIAMDNDHLDIDVDITEPSFEHLTIATVNERRMRIEIENQAISLS 307
Cdd:PRK13604  241 SSHDLGENLVVLRNFYQSVTKAAIALDNGSLDLDVDIIEPSFEDLTSATVKERRLKNEIENEALELA 307
 
Name Accession Description Interval E-value
luxD PRK13604
acyl transferase; Provisional
1-307 0e+00

acyl transferase; Provisional


Pssm-ID: 184175  Cd Length: 307  Bit Score: 588.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515   1 MENESKYKTIDHVICVEGNKKIHVWETLPEENSPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHVGLSS 80
Cdd:PRK13604    1 MKNESSFKTIDHVICLENGQSIRVWETLPKENSPKKNNTILIASGFARRMDHFAGLAEYLSSNGFHVIRYDSLHHVGLSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  81 GTIDEFTMSIGKQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASFLITAVGVVNLRYSLERALGFDYLSLPI 160
Cdd:PRK13604   81 GTIDEFTMSIGKNSLLTVVDWLNTRGINNLGLIAASLSARIAYEVINEIDLSFLITAVGVVNLRDTLERALGYDYLSLPI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 161 NELPDNLDFEGHKLGAEVFARDCLDFGWEDLASTINNMMYLDIPFIAFTANNDNWVKQDEVITLLSNIRSNRCKIYSLLG 240
Cdd:PRK13604  161 DELPEDLDFEGHNLGSEVFVTDCFKHGWDTLDSTINKMKGLDIPFIAFTANNDSWVKQSEVIDLLDSIRSEQCKLYSLIG 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1723414515 241 SSHDLSENLVVLRNFYQSVTKAAIAMDNDHLDIDVDITEPSFEHLTIATVNERRMRIEIENQAISLS 307
Cdd:PRK13604  241 SSHDLGENLVVLRNFYQSVTKAAIALDNGSLDLDVDIIEPSFEDLTSATVKERRLKNEIENEALELA 307
Acyl_transf_2 pfam02273
Acyl transferase; This bacterial family of Acyl transferases (or myristoyl-acp-specific ...
8-301 0e+00

Acyl transferase; This bacterial family of Acyl transferases (or myristoyl-acp-specific thioesterases) catalyze the first step in the bioluminescent fatty acid reductase system.


Pssm-ID: 111194  Cd Length: 294  Bit Score: 519.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515   8 KTIDHVICVEGNKKIHVWETLPEENSPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHVGLSSGTIDEFT 87
Cdd:pfam02273   1 KTIDHVIRVNNNREIHVWETPPKENVPKRNNTIVIASGFARRMDHFAGLAEYLSTNGFHVIRYDSLHHVGLSSGEIDEFT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  88 MSIGKQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASFLITAVGVVNLRYSLERALGFDYLSLPINELPDNL 167
Cdd:pfam02273  81 MSVGKNSLLTVIDWLKTRGINNIGLIASSLSARIAYEVISEINLSFLITAVGVVNLRDTLEKALGFDYLSLPIDELPEDL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 168 DFEGHKLGAEVFARDCLDFGWEDLASTINNMMYLDIPFIAFTANNDNWVKQDEVITLLSNIRSNRCKIYSLLGSSHDLSE 247
Cdd:pfam02273 161 DFEGHKLGSEVFVRDCFENNWDTLDSTINKVANLDIPFIAFTANNDDWVKQHEVYDLLSNIRSDKCKIYSLLGSSHDLGE 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1723414515 248 NLVVLRNFYQSVTKAAIAMDNDHLDIDVDITEPSFEHLTIATVNERRMRIEIEN 301
Cdd:pfam02273 241 NLVVLRNFYQSVTKAAIAMDGGLLEIDVDIIEPDFEQLTIATVNERRLKNEIEN 294
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
28-144 1.04e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 54.92  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  28 LPEENSPKRKnAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHvGLSSGTIDEFTmSIGKQSLLAVVDWLTTRKI 107
Cdd:COG1073    29 LPAGASKKYP-AVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGY-GESEGEPREEG-SPERRDARAAVDYLRTLPG 105
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1723414515 108 ---NNFGMLASSLSAriAYA-SLSEI--NASFLITAVGVVNLR 144
Cdd:COG1073   106 vdpERIGLLGISLGG--GYAlNAAATdpRVKAVILDSPFTSLE 146
 
Name Accession Description Interval E-value
luxD PRK13604
acyl transferase; Provisional
1-307 0e+00

acyl transferase; Provisional


Pssm-ID: 184175  Cd Length: 307  Bit Score: 588.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515   1 MENESKYKTIDHVICVEGNKKIHVWETLPEENSPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHVGLSS 80
Cdd:PRK13604    1 MKNESSFKTIDHVICLENGQSIRVWETLPKENSPKKNNTILIASGFARRMDHFAGLAEYLSSNGFHVIRYDSLHHVGLSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  81 GTIDEFTMSIGKQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASFLITAVGVVNLRYSLERALGFDYLSLPI 160
Cdd:PRK13604   81 GTIDEFTMSIGKNSLLTVVDWLNTRGINNLGLIAASLSARIAYEVINEIDLSFLITAVGVVNLRDTLERALGYDYLSLPI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 161 NELPDNLDFEGHKLGAEVFARDCLDFGWEDLASTINNMMYLDIPFIAFTANNDNWVKQDEVITLLSNIRSNRCKIYSLLG 240
Cdd:PRK13604  161 DELPEDLDFEGHNLGSEVFVTDCFKHGWDTLDSTINKMKGLDIPFIAFTANNDSWVKQSEVIDLLDSIRSEQCKLYSLIG 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1723414515 241 SSHDLSENLVVLRNFYQSVTKAAIAMDNDHLDIDVDITEPSFEHLTIATVNERRMRIEIENQAISLS 307
Cdd:PRK13604  241 SSHDLGENLVVLRNFYQSVTKAAIALDNGSLDLDVDIIEPSFEDLTSATVKERRLKNEIENEALELA 307
Acyl_transf_2 pfam02273
Acyl transferase; This bacterial family of Acyl transferases (or myristoyl-acp-specific ...
8-301 0e+00

Acyl transferase; This bacterial family of Acyl transferases (or myristoyl-acp-specific thioesterases) catalyze the first step in the bioluminescent fatty acid reductase system.


Pssm-ID: 111194  Cd Length: 294  Bit Score: 519.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515   8 KTIDHVICVEGNKKIHVWETLPEENSPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHVGLSSGTIDEFT 87
Cdd:pfam02273   1 KTIDHVIRVNNNREIHVWETPPKENVPKRNNTIVIASGFARRMDHFAGLAEYLSTNGFHVIRYDSLHHVGLSSGEIDEFT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  88 MSIGKQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASFLITAVGVVNLRYSLERALGFDYLSLPINELPDNL 167
Cdd:pfam02273  81 MSVGKNSLLTVIDWLKTRGINNIGLIASSLSARIAYEVISEINLSFLITAVGVVNLRDTLEKALGFDYLSLPIDELPEDL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 168 DFEGHKLGAEVFARDCLDFGWEDLASTINNMMYLDIPFIAFTANNDNWVKQDEVITLLSNIRSNRCKIYSLLGSSHDLSE 247
Cdd:pfam02273 161 DFEGHKLGSEVFVRDCFENNWDTLDSTINKVANLDIPFIAFTANNDDWVKQHEVYDLLSNIRSDKCKIYSLLGSSHDLGE 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1723414515 248 NLVVLRNFYQSVTKAAIAMDNDHLDIDVDITEPSFEHLTIATVNERRMRIEIEN 301
Cdd:pfam02273 241 NLVVLRNFYQSVTKAAIAMDGGLLEIDVDIIEPDFEQLTIATVNERRLKNEIEN 294
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
28-144 1.04e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 54.92  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  28 LPEENSPKRKnAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHvGLSSGTIDEFTmSIGKQSLLAVVDWLTTRKI 107
Cdd:COG1073    29 LPAGASKKYP-AVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGY-GESEGEPREEG-SPERRDARAAVDYLRTLPG 105
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1723414515 108 ---NNFGMLASSLSAriAYA-SLSEI--NASFLITAVGVVNLR 144
Cdd:COG1073   106 vdpERIGLLGISLGG--GYAlNAAATdpRVKAVILDSPFTSLE 146
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
12-133 5.64e-07

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 49.62  E-value: 5.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  12 HVICVEGNKKIHVWETLPEensPKRKNAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDsLHHVGLSS---GTIDEFTM 88
Cdd:COG2267     6 VTLPTRDGLRLRGRRWRPA---GSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFD-LRGHGRSDgprGHVDSFDD 81
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1723414515  89 SIgkQSLLAVVDWLTTRKINNFGMLASSLSARIAYASLSEINASF 133
Cdd:COG2267    82 YV--DDLRAALDALRARPGLPVVLLGHSMGGLIALLYAARYPDRV 124
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
38-212 7.09e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 40.18  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515  38 NAIIIASGFARRMDHFAGLAEYLSRNGFHVIRYDSLHHvGLSSGTIDEFTMSIGkqSLLAVVDWLTTRKIN-NFGMLASS 116
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGF-GKSSRPKAQDDYRTD--DLAEDLEYILEALGLeKVNLVGHS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723414515 117 LSARIA--YASL--SEINAsflITAVGVVNLRYSLERALG---------FDYLSLPINELPDNlDFEGHKLGAeVFARDC 183
Cdd:pfam00561  78 MGGLIAlaYAAKypDRVKA---LVLLGALDPPHELDEADRfilalfpgfFDGFVADFAPNPLG-RLVAKLLAL-LLLRLR 152
                         170       180
                  ....*....|....*....|....*....
gi 1723414515 184 LDFGWEDLASTINNMMYLDIPFIAFTANN 212
Cdd:pfam00561 153 LLKALPLLNKRFPSGDYALAKSLVTGALL 181
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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