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Conserved domains on  [gi|1890196819|gb|QNC69560|]
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L polymerase [Mammarenavirus lassaense]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arena_RNA_pol pfam06317
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 178-2212 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


:

Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3061.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  178 FEESEYSRLCESLSMTSGRLSGIESINVLKDNRTDHFTEIIANCHQGINNKMTSHEVKTMIEEEYQIFRNDLRQGVIESQ 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELEGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  258 FVATDKENLLSRFSKLYEgEIADYDDNLDQLVHQFKRASPLLRFLYAGLnEDAGRVRPADCDEQMQCWRSFLNKIKSLRI 337
Cdd:pfam06317   81 FLKVNKSQLLNELNNLYE-DKVTSDDIIEHLTFQAKRASPILRFLYANT-QDRERGNSTIGECQYQCWLSFLNKVKSLKI 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  338 LNTRRKLLLIFDAIILLASRFDLSKSKQ----RFPSGWLGSSFESVNDRLVSLESTKRDVKKWIEGRLTKNdgkkprgVN 413
Cdd:pfam06317  159 LNTRRKLLLILDALILLASKHDLFKQKAlkglRRSGLWLGQCFTSVNDRLVSFEATKEDLVKWVENRKRSK-------IL 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  414 RLYDRNETLLSIIKKTLDKAISTLKDVSIEITMYKVNMAIFDCDVFDTIMGFEMSGIVPTMSYQKTQSEMFPYTLGVVDL 493
Cdd:pfam06317  232 RSVSKNQILNSIFSKTISKAQTALLDVGISVDHYKIDMEVICHIPYDLIMDFDVSGVHPIMSYQRTKEETFPYMMGDEQL 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  494 EETIDLKRLSVVCLALINSMKTSSTVRLRQNEFGPARYQQVRCKEAYCQGFTIDGIEFKLLYQKTGECSKCYAINNNEVG 573
Cdd:pfam06317  312 LNTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARYQVVRCKEAYCQEFSLDGTEVQLIYQKTGECSKCYSINDNEDG 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  574 EVCSFYADPKRFFPAIFSDSVLQSVVDIMMSWIEDCIELKAKLKTVKLLTKMILVMVLVHPSKRCQKFLQNLRYFIMAFV 653
Cdd:pfam06317  392 ELCSFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLEDQLVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYV 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  654 SDFHHKDLMDKIKEDLITEAELILYKLVRFLLETLLSSDISSMMTNRFKFILNVSYMCHFITKETPDRLTDQIKCFEKFL 733
Cdd:pfam06317  472 SDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKSMMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFL 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  734 EPKLDFGHVSVNPRDQPEEEELEDMIHSIRRFL-KKDTCTDgkgikFKKPGVSKKYLSLLTSSFNNGSLFKEKEVKRELK 812
Cdd:pfam06317  552 EPKVDFGHVSVNPADTATEEEEDDMVYNAKKFLsKTLDCTD-----YKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIK 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  813 DPLITSGcATALDLASNKSVVINKYTDGTRVLDYDFNKLTALAVTQLTEVFSRKGKYLLNKQDYDYKIQQAMSNLVLGPD 892
Cdd:pfam06317  627 DPLITSG-STALDLASNKSVVVNKYTDGSRVLNYDFNKLTASAVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVIGSK 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  893 QQKVGVEDGDLDDILFEG-GASEYFERLRATVDKIVSQYREPNVEKNSLIGEGH-----PSVADLERVIDNKF-YIRLIK 965
Cdd:pfam06317  706 QEKTDRDEADLDEILFDGlEASEYFNQLKETVEKIVDQYREPVKGGSGNNGDGRvksstPSLNDLDEIVSGKFgYIRLIK 785

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  966 GELSNHMVEDFDYEILPEEFYKSFCDSIYDNSDLQKKYFYSGPMNSCPIGELTKAVVTRTYLEAEYFQCFKSILLVMNAN 1045
Cdd:pfam06317  786 GELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSLKPKYFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNAN 865

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1046 KLMGRYSHYRTKCLNFKFDTGRLTDDVRISERESNSEALSKALSLTNCTTAMLKNLCFYSQESPQSYNSIGPDTGRLKFS 1125
Cdd:pfam06317  866 ALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSEALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFS 945

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1126 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEALTGQLTGSCLNNEKEFDNAILSMKLNVSLAHVSYSMDHSKWGPMMCP 1205
Cdd:pfam06317  946 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQLSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCP 1025

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1206 FLFLAVLQNLVLLSKDLQADVKGRDYLSTLLTWHIHKMVEIPFNVASAMMKSYIKSQLGLRKRTSRTVTEDFFYSNFQMG 1285
Cdd:pfam06317 1026 FLFLTFLQNLILLSKDLQADIKGRDYVSTLLMWHMHKMVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQVG 1105

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1286 VVPSHISSVLDMGQGILHNTSDFYALISERFINYAIKCVCGGQIDAYTSSDDQISLFDQNLTELLSRDPEEFRILLEFHH 1365
Cdd:pfam06317 1106 VVPSHISSILDMGQGILHNTSDFYGLITERFINYAISCICGGTPDAYTSSDDQITLFDQQLTDLLVRDPEEFLELLEFHY 1185

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1366 YMSDQLNKFISPKSVIGRFVAEFKSRFYVWGDEVPLMTKFVAAALHNIKCKEPHQLAETIDTIIDQSVANGVPVHLCNLI 1445
Cdd:pfam06317 1186 YLSDQLNKFVSPKSVAGRFVAEFKSRFFVWGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLI 1265

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1446 QSRTLALLHYSRYPLDPFLLNCDTDVRDWVDGNRSYRIMRQIERLTPDACKKVRSMLRILFNKLKTGELHEEFTTNYLSG 1525
Cdd:pfam06317 1266 QQRTLQLLKYARFPIDPFLLNCETDVKDWVDGNRGYRIQRQIEGLIPDATSKIRSMLRRLYNRLKTGQLHEEFTTNLLSR 1345

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1526 EHTASLRNLFKLLDVEPVSESDL----GYCWMNLAAHHPLRMVLRQKIVYSGAVNLDEEKVPTIVKTLQNKLSSAFTRGA 1601
Cdd:pfam06317 1346 DHLSALLNLCELLGVEPPSESDLmralEYSWLNLAAHHPLRMVLRQKIIYSGAVNLDDEKIPTLIKTLQNKLSSTFTRGA 1425

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1602 QKLLSEAINKSAFQSSIASGFIGLCRTLGSKCVRGPERETLYIKSVQAQVMSIEGIQLELDEQGIQLWKIPPGVRLDQNP 1681
Cdd:pfam06317 1426 QKLLSEAINKSAFQSSIASGFIGLCKTLGSKCVRGPNKENLYIKSIQDLITDVKGICLVCNSRGVQYWRVPLELRNESES 1505

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1682 ATSYLRPLMWDYMCIALSTAIELGAWVLGEPKEAKNLGFFKHNPCDYFPLRPTASKLLEDRVGANHIIHSLRRLYPSIFE 1761
Cdd:pfam06317 1506 IVSYFRPLLWDYMCISLSNAIELGAWVLGEPKTPKVLSFFKHNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFE 1585

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1762 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEAMSLVSHIVKWKREEHYIVLASELRNSHTRIHEPMVEERVV**** 1841
Cdd:pfam06317 1586 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSD 1665

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1842 VLDYFMRQIYFESYVRSFVATTGTLGSFTWFPHKSSVPEGEGLKRLGPFSSFVEKVIHKGIERPMLKFDLMMGYAWIDFD 1921
Cdd:pfam06317 1666 VCDNFMRQIYFESYVRPFVATTRTLGSFTWFPHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYAWIDFD 1745

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1922 IEPARMNFNQLIASGLTEEMKLDSLETFLDCMSELPIGSIKFTQTIRYRIKSQDASFKETFSIHLNMSGFIDQQGRYVVC 2001
Cdd:pfam06317 1746 IEDVRFNQNQLIAQGLVDPKHFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTCSLNQQAVYLVH 1825

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2002 DVQPMYSGPVCTSVLVDCWRLAASSPVFKGKSTWFINSEVVNEFLDHTEQMGDVIPIDLVIEADKLQFHEYDFVMVGPEV 2081
Cdd:pfam06317 1826 DVTQMYSGAVSPCVLSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLGHVTPVELILDMERLQFDEYDFTLVGPCD 1905

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2082 EPVPLVVCRGSLWEGDKKLASFSPTIHDQDLDMFIKEAGD----------------SSRDLLVGALKSMISDRLRQRMQW 2145
Cdd:pfam06317 1906 EPVPLVVRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDpedvnallnqlwpylkTTSDLLLGALSDMILDRLGLDMHR 1985

                         2010      2020      2030      2040      2050      2060
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1890196819 2146 TGvdivavltrqrpddhkdvLSTLLEGLDDWVEFRGYSLCYSKSRKSVMVQSSIGSLRLKGRTCVEL 2212
Cdd:pfam06317 1986 SG------------------LSAVLELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEEL 2034
ArenaCapSnatch super family cl29053
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 1.39e-88

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


The actual alignment was detected with superfamily member pfam17296:

Pssm-ID: 355929  Cd Length: 171  Bit Score: 285.97  E-value: 1.39e-88
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819    2 EEDIAQVKDLVSRYLVDNERLTKQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCRANGCEHNTEDKSVEIILNENGILTP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819   82 ALCFVVPDGYKLTGNVLILLECFVRSSSANFEQKYLEDFKKLEQLKSDLESVNINLIPLIDGRTTFYNDQIPDWVNDKLR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 1890196819  162 DTLFSLLKFSQ 172
Cdd:pfam17296  161 DLLFELLRYSR 171
 
Name Accession Description Interval E-value
Arena_RNA_pol pfam06317
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 178-2212 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3061.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  178 FEESEYSRLCESLSMTSGRLSGIESINVLKDNRTDHFTEIIANCHQGINNKMTSHEVKTMIEEEYQIFRNDLRQGVIESQ 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELEGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  258 FVATDKENLLSRFSKLYEgEIADYDDNLDQLVHQFKRASPLLRFLYAGLnEDAGRVRPADCDEQMQCWRSFLNKIKSLRI 337
Cdd:pfam06317   81 FLKVNKSQLLNELNNLYE-DKVTSDDIIEHLTFQAKRASPILRFLYANT-QDRERGNSTIGECQYQCWLSFLNKVKSLKI 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  338 LNTRRKLLLIFDAIILLASRFDLSKSKQ----RFPSGWLGSSFESVNDRLVSLESTKRDVKKWIEGRLTKNdgkkprgVN 413
Cdd:pfam06317  159 LNTRRKLLLILDALILLASKHDLFKQKAlkglRRSGLWLGQCFTSVNDRLVSFEATKEDLVKWVENRKRSK-------IL 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  414 RLYDRNETLLSIIKKTLDKAISTLKDVSIEITMYKVNMAIFDCDVFDTIMGFEMSGIVPTMSYQKTQSEMFPYTLGVVDL 493
Cdd:pfam06317  232 RSVSKNQILNSIFSKTISKAQTALLDVGISVDHYKIDMEVICHIPYDLIMDFDVSGVHPIMSYQRTKEETFPYMMGDEQL 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  494 EETIDLKRLSVVCLALINSMKTSSTVRLRQNEFGPARYQQVRCKEAYCQGFTIDGIEFKLLYQKTGECSKCYAINNNEVG 573
Cdd:pfam06317  312 LNTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARYQVVRCKEAYCQEFSLDGTEVQLIYQKTGECSKCYSINDNEDG 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  574 EVCSFYADPKRFFPAIFSDSVLQSVVDIMMSWIEDCIELKAKLKTVKLLTKMILVMVLVHPSKRCQKFLQNLRYFIMAFV 653
Cdd:pfam06317  392 ELCSFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLEDQLVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYV 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  654 SDFHHKDLMDKIKEDLITEAELILYKLVRFLLETLLSSDISSMMTNRFKFILNVSYMCHFITKETPDRLTDQIKCFEKFL 733
Cdd:pfam06317  472 SDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKSMMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFL 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  734 EPKLDFGHVSVNPRDQPEEEELEDMIHSIRRFL-KKDTCTDgkgikFKKPGVSKKYLSLLTSSFNNGSLFKEKEVKRELK 812
Cdd:pfam06317  552 EPKVDFGHVSVNPADTATEEEEDDMVYNAKKFLsKTLDCTD-----YKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIK 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  813 DPLITSGcATALDLASNKSVVINKYTDGTRVLDYDFNKLTALAVTQLTEVFSRKGKYLLNKQDYDYKIQQAMSNLVLGPD 892
Cdd:pfam06317  627 DPLITSG-STALDLASNKSVVVNKYTDGSRVLNYDFNKLTASAVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVIGSK 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  893 QQKVGVEDGDLDDILFEG-GASEYFERLRATVDKIVSQYREPNVEKNSLIGEGH-----PSVADLERVIDNKF-YIRLIK 965
Cdd:pfam06317  706 QEKTDRDEADLDEILFDGlEASEYFNQLKETVEKIVDQYREPVKGGSGNNGDGRvksstPSLNDLDEIVSGKFgYIRLIK 785

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  966 GELSNHMVEDFDYEILPEEFYKSFCDSIYDNSDLQKKYFYSGPMNSCPIGELTKAVVTRTYLEAEYFQCFKSILLVMNAN 1045
Cdd:pfam06317  786 GELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSLKPKYFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNAN 865

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1046 KLMGRYSHYRTKCLNFKFDTGRLTDDVRISERESNSEALSKALSLTNCTTAMLKNLCFYSQESPQSYNSIGPDTGRLKFS 1125
Cdd:pfam06317  866 ALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSEALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFS 945

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1126 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEALTGQLTGSCLNNEKEFDNAILSMKLNVSLAHVSYSMDHSKWGPMMCP 1205
Cdd:pfam06317  946 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQLSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCP 1025

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1206 FLFLAVLQNLVLLSKDLQADVKGRDYLSTLLTWHIHKMVEIPFNVASAMMKSYIKSQLGLRKRTSRTVTEDFFYSNFQMG 1285
Cdd:pfam06317 1026 FLFLTFLQNLILLSKDLQADIKGRDYVSTLLMWHMHKMVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQVG 1105

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1286 VVPSHISSVLDMGQGILHNTSDFYALISERFINYAIKCVCGGQIDAYTSSDDQISLFDQNLTELLSRDPEEFRILLEFHH 1365
Cdd:pfam06317 1106 VVPSHISSILDMGQGILHNTSDFYGLITERFINYAISCICGGTPDAYTSSDDQITLFDQQLTDLLVRDPEEFLELLEFHY 1185

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1366 YMSDQLNKFISPKSVIGRFVAEFKSRFYVWGDEVPLMTKFVAAALHNIKCKEPHQLAETIDTIIDQSVANGVPVHLCNLI 1445
Cdd:pfam06317 1186 YLSDQLNKFVSPKSVAGRFVAEFKSRFFVWGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLI 1265

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1446 QSRTLALLHYSRYPLDPFLLNCDTDVRDWVDGNRSYRIMRQIERLTPDACKKVRSMLRILFNKLKTGELHEEFTTNYLSG 1525
Cdd:pfam06317 1266 QQRTLQLLKYARFPIDPFLLNCETDVKDWVDGNRGYRIQRQIEGLIPDATSKIRSMLRRLYNRLKTGQLHEEFTTNLLSR 1345

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1526 EHTASLRNLFKLLDVEPVSESDL----GYCWMNLAAHHPLRMVLRQKIVYSGAVNLDEEKVPTIVKTLQNKLSSAFTRGA 1601
Cdd:pfam06317 1346 DHLSALLNLCELLGVEPPSESDLmralEYSWLNLAAHHPLRMVLRQKIIYSGAVNLDDEKIPTLIKTLQNKLSSTFTRGA 1425

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1602 QKLLSEAINKSAFQSSIASGFIGLCRTLGSKCVRGPERETLYIKSVQAQVMSIEGIQLELDEQGIQLWKIPPGVRLDQNP 1681
Cdd:pfam06317 1426 QKLLSEAINKSAFQSSIASGFIGLCKTLGSKCVRGPNKENLYIKSIQDLITDVKGICLVCNSRGVQYWRVPLELRNESES 1505

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1682 ATSYLRPLMWDYMCIALSTAIELGAWVLGEPKEAKNLGFFKHNPCDYFPLRPTASKLLEDRVGANHIIHSLRRLYPSIFE 1761
Cdd:pfam06317 1506 IVSYFRPLLWDYMCISLSNAIELGAWVLGEPKTPKVLSFFKHNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFE 1585

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1762 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEAMSLVSHIVKWKREEHYIVLASELRNSHTRIHEPMVEERVV**** 1841
Cdd:pfam06317 1586 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSD 1665

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1842 VLDYFMRQIYFESYVRSFVATTGTLGSFTWFPHKSSVPEGEGLKRLGPFSSFVEKVIHKGIERPMLKFDLMMGYAWIDFD 1921
Cdd:pfam06317 1666 VCDNFMRQIYFESYVRPFVATTRTLGSFTWFPHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYAWIDFD 1745

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1922 IEPARMNFNQLIASGLTEEMKLDSLETFLDCMSELPIGSIKFTQTIRYRIKSQDASFKETFSIHLNMSGFIDQQGRYVVC 2001
Cdd:pfam06317 1746 IEDVRFNQNQLIAQGLVDPKHFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTCSLNQQAVYLVH 1825

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2002 DVQPMYSGPVCTSVLVDCWRLAASSPVFKGKSTWFINSEVVNEFLDHTEQMGDVIPIDLVIEADKLQFHEYDFVMVGPEV 2081
Cdd:pfam06317 1826 DVTQMYSGAVSPCVLSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLGHVTPVELILDMERLQFDEYDFTLVGPCD 1905

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2082 EPVPLVVCRGSLWEGDKKLASFSPTIHDQDLDMFIKEAGD----------------SSRDLLVGALKSMISDRLRQRMQW 2145
Cdd:pfam06317 1906 EPVPLVVRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDpedvnallnqlwpylkTTSDLLLGALSDMILDRLGLDMHR 1985

                         2010      2020      2030      2040      2050      2060
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1890196819 2146 TGvdivavltrqrpddhkdvLSTLLEGLDDWVEFRGYSLCYSKSRKSVMVQSSIGSLRLKGRTCVEL 2212
Cdd:pfam06317 1986 SG------------------LSAVLELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEEL 2034
ArenaCapSnatch pfam17296
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 1.39e-88

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


Pssm-ID: 340012  Cd Length: 171  Bit Score: 285.97  E-value: 1.39e-88
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819    2 EEDIAQVKDLVSRYLVDNERLTKQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCRANGCEHNTEDKSVEIILNENGILTP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819   82 ALCFVVPDGYKLTGNVLILLECFVRSSSANFEQKYLEDFKKLEQLKSDLESVNINLIPLIDGRTTFYNDQIPDWVNDKLR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 1890196819  162 DTLFSLLKFSQ 172
Cdd:pfam17296  161 DLLFELLRYSR 171
capSnatchArena TIGR04202
RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature ...
 86-145 1.34e-24

RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature region from an RNA endonuclease region associated with cap-snatching for mRNA production by RNA viruses. This domain usually is part of a multifunctional protein, the L protein responsible for RNA-dependent RNA polymerase activity. Cap-snatching is a viral alternative to synthesizing a eukaryotic-like mRNA cap itself.


Pssm-ID: 275049  Cd Length: 61  Bit Score: 98.42  E-value: 1.34e-24
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819   86 VVPDGYKLTGNVLILLECFVRSSSANFEQKYLEDFKKLEQLKSDLESVNINLIPLIDGRT 145
Cdd:TIGR04202    1 VTPDNYKLTGNVLILLEVFVRVDPESFEKKYKEKYEKLLSLKGDLLSPGITLVPVVDGRT 60
 
Name Accession Description Interval E-value
Arena_RNA_pol pfam06317
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 178-2212 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3061.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  178 FEESEYSRLCESLSMTSGRLSGIESINVLKDNRTDHFTEIIANCHQGINNKMTSHEVKTMIEEEYQIFRNDLRQGVIESQ 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELEGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  258 FVATDKENLLSRFSKLYEgEIADYDDNLDQLVHQFKRASPLLRFLYAGLnEDAGRVRPADCDEQMQCWRSFLNKIKSLRI 337
Cdd:pfam06317   81 FLKVNKSQLLNELNNLYE-DKVTSDDIIEHLTFQAKRASPILRFLYANT-QDRERGNSTIGECQYQCWLSFLNKVKSLKI 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  338 LNTRRKLLLIFDAIILLASRFDLSKSKQ----RFPSGWLGSSFESVNDRLVSLESTKRDVKKWIEGRLTKNdgkkprgVN 413
Cdd:pfam06317  159 LNTRRKLLLILDALILLASKHDLFKQKAlkglRRSGLWLGQCFTSVNDRLVSFEATKEDLVKWVENRKRSK-------IL 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  414 RLYDRNETLLSIIKKTLDKAISTLKDVSIEITMYKVNMAIFDCDVFDTIMGFEMSGIVPTMSYQKTQSEMFPYTLGVVDL 493
Cdd:pfam06317  232 RSVSKNQILNSIFSKTISKAQTALLDVGISVDHYKIDMEVICHIPYDLIMDFDVSGVHPIMSYQRTKEETFPYMMGDEQL 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  494 EETIDLKRLSVVCLALINSMKTSSTVRLRQNEFGPARYQQVRCKEAYCQGFTIDGIEFKLLYQKTGECSKCYAINNNEVG 573
Cdd:pfam06317  312 LNTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARYQVVRCKEAYCQEFSLDGTEVQLIYQKTGECSKCYSINDNEDG 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  574 EVCSFYADPKRFFPAIFSDSVLQSVVDIMMSWIEDCIELKAKLKTVKLLTKMILVMVLVHPSKRCQKFLQNLRYFIMAFV 653
Cdd:pfam06317  392 ELCSFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLEDQLVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYV 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  654 SDFHHKDLMDKIKEDLITEAELILYKLVRFLLETLLSSDISSMMTNRFKFILNVSYMCHFITKETPDRLTDQIKCFEKFL 733
Cdd:pfam06317  472 SDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKSMMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFL 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  734 EPKLDFGHVSVNPRDQPEEEELEDMIHSIRRFL-KKDTCTDgkgikFKKPGVSKKYLSLLTSSFNNGSLFKEKEVKRELK 812
Cdd:pfam06317  552 EPKVDFGHVSVNPADTATEEEEDDMVYNAKKFLsKTLDCTD-----YKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIK 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  813 DPLITSGcATALDLASNKSVVINKYTDGTRVLDYDFNKLTALAVTQLTEVFSRKGKYLLNKQDYDYKIQQAMSNLVLGPD 892
Cdd:pfam06317  627 DPLITSG-STALDLASNKSVVVNKYTDGSRVLNYDFNKLTASAVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVIGSK 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  893 QQKVGVEDGDLDDILFEG-GASEYFERLRATVDKIVSQYREPNVEKNSLIGEGH-----PSVADLERVIDNKF-YIRLIK 965
Cdd:pfam06317  706 QEKTDRDEADLDEILFDGlEASEYFNQLKETVEKIVDQYREPVKGGSGNNGDGRvksstPSLNDLDEIVSGKFgYIRLIK 785

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819  966 GELSNHMVEDFDYEILPEEFYKSFCDSIYDNSDLQKKYFYSGPMNSCPIGELTKAVVTRTYLEAEYFQCFKSILLVMNAN 1045
Cdd:pfam06317  786 GELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSLKPKYFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNAN 865

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1046 KLMGRYSHYRTKCLNFKFDTGRLTDDVRISERESNSEALSKALSLTNCTTAMLKNLCFYSQESPQSYNSIGPDTGRLKFS 1125
Cdd:pfam06317  866 ALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSEALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFS 945

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1126 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEALTGQLTGSCLNNEKEFDNAILSMKLNVSLAHVSYSMDHSKWGPMMCP 1205
Cdd:pfam06317  946 LSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQLSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCP 1025

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1206 FLFLAVLQNLVLLSKDLQADVKGRDYLSTLLTWHIHKMVEIPFNVASAMMKSYIKSQLGLRKRTSRTVTEDFFYSNFQMG 1285
Cdd:pfam06317 1026 FLFLTFLQNLILLSKDLQADIKGRDYVSTLLMWHMHKMVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQVG 1105

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1286 VVPSHISSVLDMGQGILHNTSDFYALISERFINYAIKCVCGGQIDAYTSSDDQISLFDQNLTELLSRDPEEFRILLEFHH 1365
Cdd:pfam06317 1106 VVPSHISSILDMGQGILHNTSDFYGLITERFINYAISCICGGTPDAYTSSDDQITLFDQQLTDLLVRDPEEFLELLEFHY 1185

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1366 YMSDQLNKFISPKSVIGRFVAEFKSRFYVWGDEVPLMTKFVAAALHNIKCKEPHQLAETIDTIIDQSVANGVPVHLCNLI 1445
Cdd:pfam06317 1186 YLSDQLNKFVSPKSVAGRFVAEFKSRFFVWGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLI 1265

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1446 QSRTLALLHYSRYPLDPFLLNCDTDVRDWVDGNRSYRIMRQIERLTPDACKKVRSMLRILFNKLKTGELHEEFTTNYLSG 1525
Cdd:pfam06317 1266 QQRTLQLLKYARFPIDPFLLNCETDVKDWVDGNRGYRIQRQIEGLIPDATSKIRSMLRRLYNRLKTGQLHEEFTTNLLSR 1345

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1526 EHTASLRNLFKLLDVEPVSESDL----GYCWMNLAAHHPLRMVLRQKIVYSGAVNLDEEKVPTIVKTLQNKLSSAFTRGA 1601
Cdd:pfam06317 1346 DHLSALLNLCELLGVEPPSESDLmralEYSWLNLAAHHPLRMVLRQKIIYSGAVNLDDEKIPTLIKTLQNKLSSTFTRGA 1425

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1602 QKLLSEAINKSAFQSSIASGFIGLCRTLGSKCVRGPERETLYIKSVQAQVMSIEGIQLELDEQGIQLWKIPPGVRLDQNP 1681
Cdd:pfam06317 1426 QKLLSEAINKSAFQSSIASGFIGLCKTLGSKCVRGPNKENLYIKSIQDLITDVKGICLVCNSRGVQYWRVPLELRNESES 1505

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1682 ATSYLRPLMWDYMCIALSTAIELGAWVLGEPKEAKNLGFFKHNPCDYFPLRPTASKLLEDRVGANHIIHSLRRLYPSIFE 1761
Cdd:pfam06317 1506 IVSYFRPLLWDYMCISLSNAIELGAWVLGEPKTPKVLSFFKHNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFE 1585

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1762 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEAMSLVSHIVKWKREEHYIVLASELRNSHTRIHEPMVEERVV**** 1841
Cdd:pfam06317 1586 KHLLPFMSDLASTKMKWSPRIKFLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSD 1665

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1842 VLDYFMRQIYFESYVRSFVATTGTLGSFTWFPHKSSVPEGEGLKRLGPFSSFVEKVIHKGIERPMLKFDLMMGYAWIDFD 1921
Cdd:pfam06317 1666 VCDNFMRQIYFESYVRPFVATTRTLGSFTWFPHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYAWIDFD 1745

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 1922 IEPARMNFNQLIASGLTEEMKLDSLETFLDCMSELPIGSIKFTQTIRYRIKSQDASFKETFSIHLNMSGFIDQQGRYVVC 2001
Cdd:pfam06317 1746 IEDVRFNQNQLIAQGLVDPKHFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTCSLNQQAVYLVH 1825

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2002 DVQPMYSGPVCTSVLVDCWRLAASSPVFKGKSTWFINSEVVNEFLDHTEQMGDVIPIDLVIEADKLQFHEYDFVMVGPEV 2081
Cdd:pfam06317 1826 DVTQMYSGAVSPCVLSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLGHVTPVELILDMERLQFDEYDFTLVGPCD 1905

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819 2082 EPVPLVVCRGSLWEGDKKLASFSPTIHDQDLDMFIKEAGD----------------SSRDLLVGALKSMISDRLRQRMQW 2145
Cdd:pfam06317 1906 EPVPLVVRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDpedvnallnqlwpylkTTSDLLLGALSDMILDRLGLDMHR 1985

                         2010      2020      2030      2040      2050      2060
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1890196819 2146 TGvdivavltrqrpddhkdvLSTLLEGLDDWVEFRGYSLCYSKSRKSVMVQSSIGSLRLKGRTCVEL 2212
Cdd:pfam06317 1986 SG------------------LSAVLELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEEL 2034
ArenaCapSnatch pfam17296
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 1.39e-88

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


Pssm-ID: 340012  Cd Length: 171  Bit Score: 285.97  E-value: 1.39e-88
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819    2 EEDIAQVKDLVSRYLVDNERLTKQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCRANGCEHNTEDKSVEIILNENGILTP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819   82 ALCFVVPDGYKLTGNVLILLECFVRSSSANFEQKYLEDFKKLEQLKSDLESVNINLIPLIDGRTTFYNDQIPDWVNDKLR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 1890196819  162 DTLFSLLKFSQ 172
Cdd:pfam17296  161 DLLFELLRYSR 171
capSnatchArena TIGR04202
RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature ...
 86-145 1.34e-24

RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature region from an RNA endonuclease region associated with cap-snatching for mRNA production by RNA viruses. This domain usually is part of a multifunctional protein, the L protein responsible for RNA-dependent RNA polymerase activity. Cap-snatching is a viral alternative to synthesizing a eukaryotic-like mRNA cap itself.


Pssm-ID: 275049  Cd Length: 61  Bit Score: 98.42  E-value: 1.34e-24
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890196819   86 VVPDGYKLTGNVLILLECFVRSSSANFEQKYLEDFKKLEQLKSDLESVNINLIPLIDGRT 145
Cdd:TIGR04202    1 VTPDNYKLTGNVLILLEVFVRVDPESFEKKYKEKYEKLLSLKGDLLSPGITLVPVVDGRT 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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