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Conserved domains on  [gi|1896070333|gb|QNJ47322|]
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NADH dehydrogenase subunit 4L, partial (mitochondrion) [Atractomorpha sp. RINSinlTDFRAAPEI-84]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 8.19e-21

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 78.66  E-value: 8.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  4 FSLLTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILVCMIRS 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1896070333 84 CGNDFFNS 91
Cdd:MTH00162  82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 8.19e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 78.66  E-value: 8.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  4 FSLLTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILVCMIRS 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1896070333 84 CGNDFFNS 91
Cdd:MTH00162  82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 2.13e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 42.17  E-value: 2.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  4 FSLLTSLLIYLSGIYVFSSkRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDY--YFPVIFLVFSVCEGALGLGILVCMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1896070333 82 RSCGNDFFNSFCL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-91 8.19e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 78.66  E-value: 8.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  4 FSLLTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILVCMIRS 83
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 1896070333 84 CGNDFFNS 91
Cdd:MTH00162  82 HGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-97 6.01e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 56.52  E-value: 6.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  6 LLTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILVCMIRSCG 85
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                         90
                 ....*....|..
gi 1896070333 86 NDFFNSFCLSLC 97
Cdd:MTH00188  86 SDYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-97 6.81e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 53.70  E-value: 6.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  1 MLNFSLLTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILVCM 80
Cdd:MTH00149   1 SMFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSL 80

                         90
                 ....*....|....*..
gi 1896070333 81 IRSCGNDFFNSFCLSLC 97
Cdd:MTH00149  81 IRLHGNDYVSSLSSLKF 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-97 6.45e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 48.69  E-value: 6.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  1 MLNFSLLTSLLIYLSGiyvFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYF--PVIFLVFSVCEGALGLGILV 78
Cdd:MTH00125   3 PTHFSLYTAFMLSLLG---LSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTpmPIILLTFSACEAGTGLALLV 79

                         90
                 ....*....|....*....
gi 1896070333 79 CMIRSCGNDFFNSFCLSLC 97
Cdd:MTH00125  80 ATTRTHGSDHLKNLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 11-97 6.48e-09

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 48.59  E-value: 6.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333 11 LIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYL-FIVDYDYYFPVIFLVFSVCEGALGLGILVCMIRSCGNDFF 89
Cdd:MTH00013  10 ISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLmFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDML 89


                 ....*...
gi 1896070333 90 NSFCLSLC 97
Cdd:MTH00013  90 KSLTSNKC 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-97 1.63e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 42.28  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  1 MLNFSLLTSLLIYLSGIyvfSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYF--PVIFLVFSVCEGALGLGILV 78
Cdd:MTH00067   3 PTYFTFYSAFLLGLMGL---AFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFslPMFMLTFSACEASTGLALMV 79

                         90
                 ....*....|....*....
gi 1896070333 79 CMIRSCGNDFFNSFCLSLC 97
Cdd:MTH00067  80 ATTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 2.13e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 42.17  E-value: 2.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  4 FSLLTSLLIYLSGIYVFSSkRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDY--YFPVIFLVFSVCEGALGLGILVCMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1896070333 82 RSCGNDFFNSFCL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-97 2.68e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 41.87  E-value: 2.68e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1896070333 24 RKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYYF--PVIFLVFSVCEGALGLGILVCMIRSCGNDFFNSFCLSLC 97
Cdd:MTH00126  23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSaaPMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-97 7.74e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 37.99  E-value: 7.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  1 MLNFSLLTSLLIYLSGIYVFsskRKHLLIVLLSLEYVVLSLFMF--ILIYLFIVDYDYYFPVIFLVFSVCEGALGLGILV 78
Cdd:MTH00107   3 LIYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLV 79

                         90
                 ....*....|....*....
gi 1896070333 79 CMIRSCGNDFFNSFCLSLC 97
Cdd:MTH00107  80 MVSNTYGTDYVQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-95 2.45e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 34.15  E-value: 2.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  7 LTSLLIYLSGIYVFSSKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDY--DYYFPVIFLVFSVCEGALGLGILVCMIRSC 84
Cdd:MTH00181   3 FVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTH 82

                         90
                 ....*....|.
gi 1896070333 85 GNDFFNSFCLS 95
Cdd:MTH00181  83 GSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-91 4.61e-03

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 33.35  E-value: 4.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070333  1 MLNFSLLTSLLIYLSGIYVFSsKRKHLLIVLLSLEYVVLSLFMFILIYLFIVDYDYY--FPVIFLVFSVCEGALGLGILV 78
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILI-NRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMV 79

                         90
                 ....*....|...
gi 1896070333 79 CMIRSCGNDFFNS 91
Cdd:MTH00043  80 LLSRNHNSDLVAS 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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