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Conserved domains on  [gi|1910804110|gb|QOD97357|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Nestor notabilis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.67e-152

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 431.55  E-value: 2.67e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1910804110 321 TSVLASILTSLSILLLPLSPMILIAT 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.67e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 431.55  E-value: 2.67e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1910804110 321 TSVLASILTSLSILLLPLSPMILIAT 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 16-298 1.38e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 106.74  E-value: 1.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLF-SSMTNAWcTGQWDITQL---- 89
Cdd:COG1007   114 GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIaaal 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  90 ----TNPP----SCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTV---------MKLppTIILFLTSHSLNST 152
Cdd:COG1007   193 aaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATApkiaafaalLRL--LVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 153 LLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTL--LAFY--IYVMMTTSIFLTLNTTNTLNLS 228
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNLGAFAVILLLSRKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1910804110 229 MLTTS-----WTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAY 298
Cdd:COG1007   351 AEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 4.65e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 97.00  E-value: 4.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  23 SNHWVTMWAGLEINTLAIIPLI-SKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPSC------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 -----LLLTTAVAIKLGLAPFHFWFPEVLQGTSL-ITAMLLSTVMKLPPTII-----LFLTSHSLNSTLLTSLAIVSTAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 165 GGWMGLNQTQTRKILAFSSISHLGWMTIII----IYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLS-----MLTTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHtrnirDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1910804110 236 KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 16-297 2.84e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.16  E-value: 2.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPS 94
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  95 C------------LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIIL-------FLTSHSLNSTLLT 155
Cdd:TIGR01770 194 NgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyiLFGFSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 156 SLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLA--FY--IYVMMTTSIFLTLNTTNTL------ 225
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYifIYALMSLGAFGVLSLLRSYkdewie 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1910804110 226 NLSMLTTSWTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.67e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 431.55  E-value: 2.67e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 1910804110 321 TSVLASILTSLSILLLPLSPMILIAT 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-324 6.89e-123

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 356.92  E-value: 6.89e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                  ....
gi 1910804110 321 TSVL 324
Cdd:MTH00070  321 TNNL 324
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 2.50e-120

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 350.64  E-value: 2.50e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPtIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAP-FALILQIAPTNPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                  ....
gi 1910804110 321 TSVL 324
Cdd:MTH00135  320 QLTL 323
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-325 3.49e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 327.19  E-value: 3.49e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFK-- 318
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFEnt 320


                  ....*..
gi 1910804110 319 KPTSVLA 325
Cdd:MTH00105  321 KPMTLLP 327
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-315 2.36e-88

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 269.15  E-value: 2.36e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   1 MNPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWC 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIV 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 161 STALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1910804110 241 NTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQW 315
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 16-324 2.01e-84

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 259.09  E-value: 2.01e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPSC 95
Cdd:MTH00041   16 GTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIVSTALGGWMGLNQTQT 175
Cdd:MTH00041   96 IIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQT 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 176 RKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTLNTTLMLTLLSLAGLP 255
Cdd:MTH00041  176 RKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLP 255

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1910804110 256 PLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFKKPTSVL 324
Cdd:MTH00041  256 PLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVY 324
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 16-313 5.53e-56

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 185.41  E-value: 5.53e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWctgqwdITQLTNPPSC 95
Cdd:MTH00160   17 GTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NLMLFNNISS 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPtiiLFLTSHSLNSTLLTSLAIVSTALGGWMGLNQTQT 175
Cdd:MTH00160   91 MLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIILSAIIGAIGGLNQTSL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 176 RKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTLNTTLMLTLLSLAGLP 255
Cdd:MTH00160  168 RKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLP 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1910804110 256 PLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMK 313
Cdd:MTH00160  248 PFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLK 305
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 16-318 2.02e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 170.84  E-value: 2.02e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITqltnppsc 95
Cdd:MTH00144   16 GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM-------- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPP--TIILFLTSHSLNSTLLTsLAIVSTALGGWMGLNQT 173
Cdd:MTH00144   88 SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPlfLLSNFLDLYWLAYLLCV-ISVLSALVGSIGGLNQT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 174 QTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSwTKTPTLNTTLMLTLLSLAG 253
Cdd:MTH00144  167 QVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSLGG 245

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1910804110 254 LPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWLFK 318
Cdd:MTH00144  246 LPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNS 310
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 16-310 4.94e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 159.56  E-value: 4.94e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSmtnawcTGQWDITQLTNPPSC 95
Cdd:MTH00011   18 GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNITA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTSLAIVSTALGGWMGLNQTQT 175
Cdd:MTH00011   92 LMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 176 RKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTLNTTLMLTLLSLAGLP 255
Cdd:MTH00011  172 RPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLP 251

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1910804110 256 PLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYcSTITLPPNPSN 310
Cdd:MTH00011  252 PFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 16-313 4.19e-41

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 146.36  E-value: 4.19e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAwctgqwdITQLTNPPSC 95
Cdd:MTH00197   10 GVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF-------SNLYLSLLSV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHslNSTLLTSLAIVSTALGGWMGLNQTQT 175
Cdd:MTH00197   83 VLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGGMNQSNI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 176 RKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWTKTPTLNTTLMLTLLSLAGLP 255
Cdd:MTH00197  161 RQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLP 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1910804110 256 PLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAYCSTITLPPNPSNKMK 313
Cdd:MTH00197  241 PLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMK 298
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-296 4.43e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 106.65  E-value: 4.43e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLI-SKSHHPRAIEATIKYFLVQAMASTLVLFS-------------SMTNAWCT 81
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  82 GQWDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFltSHSLNSTLLTSLAIVS 161
Cdd:MTH00196   85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 162 TALGGWMGLNQTQTRKILAFSSISHLGWMTIII----IYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTS--WT 235
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSglSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1910804110 236 KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRL 296
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 16-298 1.38e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 106.74  E-value: 1.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLF-SSMTNAWcTGQWDITQL---- 89
Cdd:COG1007   114 GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIaaal 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  90 ----TNPP----SCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTV---------MKLppTIILFLTSHSLNST 152
Cdd:COG1007   193 aaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATApkiaafaalLRL--LVEAFPGLAADWQL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 153 LLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTL--LAFY--IYVMMTTSIFLTLNTTNTLNLS 228
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNLGAFAVILLLSRKGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1910804110 229 MLTTS-----WTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAY 298
Cdd:COG1007   351 AEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
16-296 9.80e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.44  E-value: 9.80e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPS 94
Cdd:PRK05777  115 GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKALA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  95 ------------CLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIIL-------FLTSHSLNSTLLT 155
Cdd:PRK05777  195 dgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvaFGGLSEDWQQVLA 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 156 SLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTL--LAFY--IYVMMTTSIFLTLNTTNTLNLSMLT 231
Cdd:PRK05777  275 IIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYllAYLFMTLGAFGVISLLRRKGGEAES 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 232 -TSWT----KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRL 296
Cdd:PRK05777  355 iSDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 4.65e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 97.00  E-value: 4.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  23 SNHWVTMWAGLEINTLAIIPLI-SKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPSC------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  96 -----LLLTTAVAIKLGLAPFHFWFPEVLQGTSL-ITAMLLSTVMKLPPTII-----LFLTSHSLNSTLLTSLAIVSTAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 165 GGWMGLNQTQTRKILAFSSISHLGWMTIII----IYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLS-----MLTTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHtrnirDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1910804110 236 KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 16-297 2.84e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.16  E-value: 2.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPS 94
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  95 C------------LLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIIL-------FLTSHSLNSTLLT 155
Cdd:TIGR01770 194 NgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyiLFGFSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 156 SLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLA--FY--IYVMMTTSIFLTLNTTNTL------ 225
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYifIYALMSLGAFGVLSLLRSYkdewie 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1910804110 226 NLSMLTTSWTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLA 297
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-296 3.65e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.15  E-value: 3.65e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDI----TQLT 90
Cdd:MTH00199  109 GSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginSILT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  91 NPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNSTLLTslAIVSTALGGWMGL 170
Cdd:MTH00199  189 GDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAIGAL 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 171 NQTQTRKILAFSSISHLGW----MTIIIIYNPKLTLLAFYIYVMMTTSIFLTlnttntlnlsMLTTSWTKTPT------- 239
Cdd:MTH00199  267 NQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFSI----------ILSLKLTKGLIvevsgls 336

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1910804110 240 -----LNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRL 296
Cdd:MTH00199  337 rknpvIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-296 1.33e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 83.75  E-value: 1.33e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAI---------EATIKYFLVQAMASTLVLFSSMTNAWCTGQ--- 83
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  84 -----------WDITQLTNPPSCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMKLppTIILFLTSHSLNST 152
Cdd:MTH00198  280 lgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITSK 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 153 LLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYVM--MTTSIFLTLNTTNTLNLSML 230
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVtyLVSALASFTVICTLEEFGTR 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 231 TTSWTK-----------------------TPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSL 287
Cdd:MTH00198  438 TPTSRQrdgsfgnynlvrrlvdltilsrgQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIYYLVAL 517

                         330
                  ....*....|....*.
gi 1910804110 288 LGL-------FFYLRL 296
Cdd:MTH00198  518 FAIictcisaFYYIRI 533
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 16-296 9.41e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.58  E-value: 9.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  16 GTTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLT----- 90
Cdd:COG0651   119 GMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAarlae 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  91 -NPP----SCLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVM-KLPP-------TIILFLTSHSLNSTLLTSL 157
Cdd:COG0651   199 lDPGlllaAFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVyailrvlTLLFGADPALFLGTLLLVL 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 158 AIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIII-IYNPKLTLLAFYIYV---MMTTSIF----LTLNTTNTLNLSM 229
Cdd:COG0651   279 GLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLgLGTPLGLAGALFHLLnhaLAKALLFlaagAIERATGTRDLDK 358

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1910804110 230 LTTSWTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRL 296
Cdd:COG0651   359 LGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-209 8.77e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 62.71  E-value: 8.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  51 RAIEATIKYFLVQAMASTLVLFS-SMTNAWCTGQWDI---------TQLTNPPSCLL----LTTAVAIKLGLAPFHFWFP 116
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELqeivnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 117 EVLQG-----------TSLITAMLLSTVMKlppTIILFLTSHSLNStLLTSLAIVSTALGGWMGLNQTQTRKILAFSSIS 185
Cdd:CHL00049  239 DVYEGsptpvvaflsvTSKVAASALATRIF---DIPFYFSSNEWHL-LLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1910804110 186 HLGWMTIIII-------YNPKLTLLAFYIYV 209
Cdd:CHL00049  315 QIGYVIIGIIvgdsndgYASMITYMLFYIFM 345
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 2.98e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 57.97  E-value: 2.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  33 LEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFS-SMTNAwCTGQWDITQLTN--PPSCLLLT------TAVA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAGalAENPTVVTafgfvlLALA 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 104 IKLGLAPFHFWFPEVLQGTS-LITAMLLSTVMKLP--PTIILFLT-------SHSLNSTLLTSLAIVSTALGGWMGLNQT 173
Cdd:PRK08375  214 LKAAVFPLHTWLPRAYPAAPpVVTALLSGLVTKVAvyALIRIYFTvfggdfrFALGLGWLLAVLALLSMLVGSLAALGQD 293

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 174 QTRKILAFSSISHLGWMTIIIIYNPKLTLLA--FYI--YVMMTTSIFLTLNTTNTLNLSMLTTSWTKTP----TLNTTLM 245
Cdd:PRK08375  294 DVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAGAIEVTYGTRRLSELSGLGrrmpLTAAAFA 373

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1910804110 246 LTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFFYLRLAY 298
Cdd:PRK08375  374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 6.94e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 53.95  E-value: 6.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  33 LEINTLAIIPLIS-KSHHPRAIEATIKYFLVQAMASTLVLFSSmtnAWCTGQWDI-------TQLTNPPSCL------LL 98
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTlnmaylaVKMSENPTVVakialaLF 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  99 TTAVAIKLGLAPFHFWFPEVL-QGTSLITAMLLstVMKLPPTIILFLTSHSLNSTLLTS---------LAIVSTALGGWM 168
Cdd:PRK08376  227 IAGLAMKSGAVPVHMWLPDAYpAAPSSISAMLL--VIKQAGLYALARVLFSIYGPAINLatvgwviiiLGCLTMFVGVAM 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 169 GLNQTQTRKILAFSSISHLGWMTI---IIIYNPKLTLLAFYIYVMMTTSIFLTLNTTNTLNLSMLTTSWT---------- 235
Cdd:PRK08376  305 AVVQKDVKRLLAYHSVSQIGYMLLglgVGLAALGDPAMASYGEIALAGGIYHIVNHALYKALLFLTAGAViyetgtrnln 384

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1910804110 236 -------KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLI 266
Cdd:PRK08376  385 elgglarTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 7.73e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 53.79  E-value: 7.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  50 PRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQ-WDITQLTNPPSCLLLTT--------AVAIKLGLAPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGVQTwlflaffiAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 120 QGTSLITAMLLSTVMKLPP------TIILFLTSHSLNSTLLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTII 193
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTygflrfNLPLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLG 311


                  .
gi 1910804110 194 I 194
Cdd:TIGR01972 312 I 312
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-192 1.30e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.13  E-value: 1.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  50 PRAIEATIKYFLVQAMASTLVLF-SSMTNAWCTGQWDIT----QLTNPPSCLLLTTAV------AIKLGLAPFHFWFPEV 118
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALALVfviagiAFKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 119 LQGTSLITAMLLSTVMK---LPPTIILFLTSHSLNST----LLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMT 191
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKaagFALAIRLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316


                  .
gi 1910804110 192 I 192
Cdd:PRK02504  317 I 317
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-194 3.29e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 51.68  E-value: 3.29e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  17 TTITISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMA------STLVLFSSMTNAWCTGQWDITQLT 90
Cdd:PRK08676  115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWTELA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  91 N-----PPSCLLLT-----TAVAIKLGLAPFHFWFPEV-LQGTSLITAMLLSTVMKLPPTIILFLTS-------HSLNST 152
Cdd:PRK08676  195 AhasllSPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSAllrqsgaAEQFSN 274

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1910804110 153 LLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIII 194
Cdd:PRK08676  275 VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-204 9.78e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 50.69  E-value: 9.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  81 TGQWDITQL-TNPPSCLLLTTAVAI-------KLGLAPFHFWFPEVLQGTSLITAMLLSTVM---------KLPPTiilF 143
Cdd:PRK12644  184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMvkagiylvaRLAPG---F 260

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1910804110 144 LTSHSLNSTLLTsLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLA 204
Cdd:PRK12644  261 ADVPVWRPTVLV-LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALA 320
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-298 1.55e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 49.61  E-value: 1.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110   2 NPHAKLILILSLLLGTTITISSNHWVTMWAGLEINTLA---IIPLISKshhpRAIEATIKYFLVQAMASTLVLFSSMTNA 78
Cdd:PRK08668   96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIY 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  79 WCTGQWDITQ----LTNPPS-------CLLLTTAVAIKLGLAPFHFWFPE-----------VLQGT-SLITAMLLSTVMK 135
Cdd:PRK08668  172 AKTGTFDFADisqgLINDTStgfalivFLFLLAFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQlSKLGAYGFLLVLY 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 136 LPPTIILFLT-----SHSLNSTLLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWmtiIIIYNPKLTLLAFY--IY 208
Cdd:PRK08668  252 VLPGTKLFSEfgtyrGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGY---ILVGLGLGTSLGFAggLF 328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 209 VMMTTSIFLTLNTTNTLNLSMLTTSWT---------KTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTA 279
Cdd:PRK08668  329 HVFNHALFKGLFFLIFAAVIYRTGTTKisemgglieKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITA 408

                         330
                  ....*....|....*....
gi 1910804110 280 TVISMLSLLGLFFYLRLAY 298
Cdd:PRK08668  409 FMAFFGSIGSFLYVFRPLA 427
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-192 4.32e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 48.39  E-value: 4.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  20 TISSNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLV------QAMASTLVLFSSMTNAWCTGQWDI--TQLTN 91
Cdd:PRK06458  124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIIcsvgvaFALFGTILVYANAATVMGDGEMAIlwTELLK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  92 PPSCL---LLTTAVAI-------KLGLAPFHFWFPEV-LQGTSLITAMLLSTVMKLPPTIIL---FLTSHSLNS----TL 153
Cdd:PRK06458  204 HASLLdptLMKLAFVFlligfgtKVGLFPMHAWLPDAhSEAPSPVSALLSGVLLNVALYAVLryyILIDAAIGSdfpgRL 283

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1910804110 154 LTSLAIVSTALGGWMGLNQTQTRKILAFSSISHLGWMTI 192
Cdd:PRK06458  284 LLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-311 6.97e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 47.38  E-value: 6.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  38 LAIIP---LISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQW--DITQLTN---PPS-----CLLLTTAVAI 104
Cdd:COG1008   142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplPLTaqlllFLAFFIAFAV 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 105 KLGLAPFHFWFPEVLQGTSLITAMLLSTVMK-----------LPptiiLFLTSHSLNSTLLTSLAIVSTALGGWMGLNQT 173
Cdd:COG1008   222 KVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLkmggygllrfaLP----LFPEASAYFAPLLAALGVIGIIYGALVALAQT 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 174 QTRKILAFSSISHLGWMTI-IIIYNPK------------------LTLLAFYIYVMM-TTSIfltlnttntlnlSMLTTS 233
Cdd:COG1008   298 DLKRLIAYSSVSHMGFVLLgIFALNPLglqgavlqmvshglitaaLFLLVGVLYDRThTRDI------------ADLGGL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 234 WTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKqemttTATVISMLSLLGLFF---YLRLAYCSTITLPPNPSN 310
Cdd:COG1008   366 AKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQ-----VNPWLAILAALGLILtaaYLLWMYQRVFFGPLKEEL 440


                  .
gi 1910804110 311 K 311
Cdd:COG1008   441 A 441
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
38-204 4.94e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 45.08  E-value: 4.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  38 LAIIPL---ISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTG----QWDITQLTNPP--SCLLLTTAV----AI 104
Cdd:PRK06473  138 LELIPLyllIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGassfDYEPLRSHTLPlsTQLLLLAPIlvgfGI 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 105 KLGLAPFHFWFPEV-LQGTSLITAMLLSTVMKLPP------TIILFLTSHSLNSTLLTSLAIVSTALGGWMGLNQTQTRK 177
Cdd:PRK06473  218 KIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTygllrfGVGLFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKK 297

                         170       180
                  ....*....|....*....|....*..
gi 1910804110 178 ILAFSSISHLGWMTIIIIYNPKLTLLA 204
Cdd:PRK06473  298 MVAYSSIGHMGYILLAAAAATPLSILA 324
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-196 9.05e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 44.43  E-value: 9.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  48 HHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQWDITQLTNPPSC--------LLLTTAVAIKLGLA------PFHF 113
Cdd:PRK12649  156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghpLFLITLILIFIGAAaksaqgPFYI 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 114 WFPEVLQGTSLITAMLLSTVMkLPPTIILFLTSHSLNS------TLLTSLAIVSTALGGWMGLNQTQTRKILAFSSISHL 187
Cdd:PRK12649  236 WLPNAMEAPTPVSAFLHSATM-VKAGVYLVARIHPIFSgteawfILVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQL 314


                  ....*....
gi 1910804110 188 GWMTIIIIY 196
Cdd:PRK12649  315 AYLMTMYGY 323
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-194 1.50e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 43.27  E-value: 1.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  50 PRAIEATIKYFLVQAMASTLVLFSSMTNAWC----TGQWDITQLTNPPSCLLLTT--------AVAIKLGLAPFHFWFPE 117
Cdd:PRK05846  157 KNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLLNLPLPPGVQYwlflaffiAFAVKMPMFPLHTWLPD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 118 VLQGTSLITAMLLSTVM-----------KLPptiiLF-LTSHSLnSTLLTSLAIVSTALGGWMGLNQTQTRKILAFSSIS 185
Cdd:PRK05846  237 AHVQAPTAGSVLLAGILlkmgaygllrfSLP----LFpDASHEF-APIIITLGVIAIIYGALVALAQTDIKKLIAYSSIS 311


                  ....*....
gi 1910804110 186 HLGWMTIII 194
Cdd:PRK05846  312 HMGFVTLGI 320
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 23-292 3.10e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 42.41  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  23 SNHWVTMWAGLEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFS-----------SMTNAWCTGQWDITQLTN 91
Cdd:PRK12662  129 SNDVFNIYVFLEISSISSYVLVAMGRDKKALVAAFEYLIIGTIGATFYLIGigflyaitgtlNMGDMFLIIQDLPTNRAI 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  92 PPSCLLLTTAVAIKLGLAPFHFWFPEVL-QGTSLITAMLLSTVMKLPPTII-----------LFLTSHSLNSTLLTsLAI 159
Cdd:PRK12662  209 QIGVLFIMVGLFIKAALFPFHKWLIQAYsEAPSFISVFFSGTSTKVMIYLIirivydvfkanFVFTTLPFNNVFMI-LAA 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110 160 VSTALGGWMGLNQTQTRKILAFSSISHLGWMTIIIIYNPKLTLLAFYIYV----MMTTSIFLTLNTTN----TLNLSMLT 231
Cdd:PRK12662  288 LAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIvnhsIVKSALFMVSGSISyhfgTTKLEDCL 367

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1910804110 232 TSWTKTPTLNTTLMLTLLSLAGLPPLSGFLPKWLIIQELIKQEMTTTATVISMLSLLGLFF 292
Cdd:PRK12662  368 NLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIY 428
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 29-194 1.01e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 40.79  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  29 MWaglEINTLAIIPLISKSHHPRAIEATIKYFLVQAMASTLVLFSSMTNAWCTGQ--WDITQLT--NPPSCLLL------ 98
Cdd:PRK12561  115 MW---ELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSGDTftFDLAELGakSYPLALELllyagf 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  99 TTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVMK-------LPPTIILFLTSHSLNSTLLTSLAIVSTALGGWMGLN 171
Cdd:PRK12561  192 LIAFGVKLPIFPLHTWLPDAHGEASAPVSMILAGVLLkmggyalIRFNVQMLPDAHVYFAPALAILGVVNIIYGALNAFA 271

                         170       180
                  ....*....|....*....|...
gi 1910804110 172 QTQTRKILAFSSISHLGWMTIII 194
Cdd:PRK12561  272 QDNVKRRLAYSSVSHMGFVLLGI 294
PRK12650 PRK12650
DUF4040 family protein;
98-194 1.36e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.80  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  98 LTTAVAIKLGLA--------PFHFWFPEVLQGTSLITAMLLSTVMKLPPTIILFLTSHSLNST-----LLTSLAIVSTAL 164
Cdd:PRK12650  206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVavwnwLLIIVGMITALM 285

                          90       100       110
                  ....*....|....*....|....*....|
gi 1910804110 165 GGWMGLNQTQTRKILAFSSISHLGWMTIII 194
Cdd:PRK12650  286 GAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 95-192 2.20e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 39.75  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1910804110  95 CLLLTTAVAIKLGLAPFHFWFPEVLQGTSLITAMLLSTVM---------KLPPtiiLFltshSLNSTLLTSLAIV--STA 163
Cdd:COG1009   214 LLLLLLGAFGKSAQFPLHFWLPDAMEGPTPVSALLHAATMvkagvyllaRLSP---LF----ALSPVWLTVVAIIgaITA 286

                          90       100       110
                  ....*....|....*....|....*....|
gi 1910804110 164 L-GGWMGLNQTQTRKILAFSSISHLGWMTI 192
Cdd:COG1009   287 LfAALIALAQTDIKRVLAYSTVSQLGYMFL 316
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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